C. Rubio

发表

Embryonic cell-free DNA versus trophectoderm biopsy for aneuploidy testing: concordance rate and clinical implications.

D. Valbuena, C. Simón, C. Rubio, 2019, Fertility and sterility.

FISH screening of aneuploidies in preimplantation embryos to improve IVF outcome.

A. Mercader, C. Simón, C. Rubio, 2005, Reproductive biomedicine online.

Preimplantation genetic testing for aneuploidy in patients with partial X monosomy using their own oocytes: is this a suitable indication?

A. Mercader, M. Meseguer, C. Rubio, 2020, Fertility and sterility.

Diagnosis of human preimplantation embryo viability.

David K Gardner, Marcos Meseguer, M. Meseguer, 2015, Human reproduction update.

Prospective cohort study in high responder oocyte donors using two hormonal stimulation protocols: impact on embryo aneuploidy and development.

A. Mercader, C. Rubio, J. Remohi, 2010, Human reproduction.

Testicular sperm from patients with obstructive and nonobstructive azoospermia: aneuploidy risk and reproductive prognosis using testicular sperm from fertile donors as control samples.

V. Peinado, C. Simón, C. Rubio, 2011, Fertility and sterility.

Prognostic factors for preimplantation genetic screening in repeated pregnancy loss.

V. Peinado, A. Mercader, C. Simón, 2009, Reproductive biomedicine online.

In vitro fertilization with preimplantation genetic diagnosis for aneuploidies in advanced maternal age: a randomized, controlled study.

C. Simón, C. Rubio, J. Bellver, 2017, Fertility and sterility.

Cost-effectiveness of preimplantation genetic testing for aneuploidies.

C. Rubio, A. Capalbo, P. Viganò, 2019, Fertility and sterility.

Sperm chromosomal abnormalities and their contribution to human embryo aneuploidy

V. Peinado, A. Mercader, M. Meseguer, 2019, Biology of Reproduction.

Advanced paternal age does not affect embryo aneuploidy following blastocyst biopsy in egg donor cycles

C. Rubio, C. Cinnioğlu, R. Carrasquillo, 2019, Journal of Assisted Reproduction and Genetics.

The Bisphenol A Experience: A Primer for the Analysis of Environmental Effects on Mammalian Reproduction1

P. Hunt, C. Rubio, T. Hassold, 2009, Biology of reproduction.

Clinical reassessment of human embryo ploidy status between cleavage and blastocyst stage by Next Generation Sequencing

C. Rubio, B. Lawrenz, A. Liñán, 2018, PloS one.

The effect of pronuclear morphology on early development and chromosomal abnormalities in cleavage-stage embryos.

A. Mercader, C. Simón, C. Rubio, 2003, Human reproduction.

The Patient Evaluation of the Future: Genetics, New Diagnostics, and Prediction Modeling

C. Rubio, A. Capalbo, M. Poli, 2020 .

BACs-on-Beads Technology: A Reliable Test for Rapid Detection of Aneuploidies and Microdeletions in Prenatal Diagnosis

C. Simón, C. Rubio, V. Serra, 2014, BioMed research international.

In vitro production of haploid cells after coculture of CD49f+ with Sertoli cells from testicular sperm extraction in nonobstructive azoospermic patients.

C. Simón, C. Rubio, A. Pellicer, 2012, Fertility and sterility.

The role of thrombophilia and thyroid autoimmunity in unexplained infertility, implantation failure and recurrent spontaneous abortion.

C. Rubio, V. Serra, J. Bellver, 2007, Human reproduction.

Implications of Sperm Chromosome Abnormalities in Recurrent Miscarriage

C. Simón, C. Rubio, J. Remohi, 1999, Journal of Assisted Reproduction and Genetics.

FISH Preimplantation Diagnosis of Chromosome Aneuploidy in Recurrent Pregnancy Wastage

C. Simón, C. Rubio, C. Giménez, 1998, Journal of Assisted Reproduction and Genetics.

Origin of tripronucleate zygotes after intracytoplasmic sperm injection.

C. Rubio, A. Pellicer, J. Egozcue, 1997, Human reproduction.

Redefining advanced maternal age as an indication for preimplantation genetic screening.

V. Peinado, A. Mercader, C. Simón, 2010, Reproductive biomedicine online.

The importance of good practice in preimplantation genetic screening: critical viewpoints.

C. Rubio, C. Giménez, L. Rodrigo, 2009, Human reproduction.

Parameters impacting the live birth rate per transfer after frozen single euploid blastocyst transfer

C. Rubio, N. Findikli, M. Bahçeci, 2020, PloS one.

Preimplantation genetic screening using fluorescence in situ hybridization in patients with repetitive implantation failure and advanced maternal age: two randomized trials.

A. Mercader, C. Simón, C. Rubio, 2013, Fertility and sterility.

Use of array comparative genomic hybridization (array-CGH) for embryo assessment: clinical results.

V. Peinado, C. Simón, C. Rubio, 2013, Fertility and sterility.

Update on preimplantation genetic diagnosis for chromosomal abnormalities

C. Rubio, 2010, Expert review of molecular diagnostics.

Variables associated with mitochondrial copy number in human blastocysts: what can we learn from trophectoderm biopsies?

A. Mercader, M. Meseguer, C. Rubio, 2018, Fertility and sterility.

Pre-implantation Genetic Testing

C. Rubio, N. Treff, 2017 .

The dawn of the future: 30 years from the first biopsy of a human embryo. The detailed history of an ongoing revolution.

C. Rubio, L. Rienzi, D. Cimadomo, 2020, Human reproduction update.

ESHRE survey results and good practice 1 recommendations on Chromosomal 2 Mosaicism 3

J. Vermeesch, C. Rubio, A. Capalbo, 2022 .

ESHRE PGT Consortium good practice recommendations for the organisation of PGT†

C. Rubio, C. Moutou, V. Goossens, 2020, Human reproduction open.

Use of fluorescence in situ hybridization to assess the chromosomal status of embryos obtained from cryopreserved oocytes.

C. Rubio, J. Remohi, A. Pellicer, 2001, Fertility and sterility.

High frequency of chromosomal abnormalities in embryos obtained from oocyte donation cycles.

C. Rubio, J. Remohi, A. Pellicer, 2003, Fertility and sterility.

Characteristics of the IVF Cycle that Contribute to the Incidence of Mosaicism

V. Peinado, C. Simón, C. Rubio, 2020, Genes.

Assessing the true incidence of mosaicism in preimplantation embryos.

M. Vera-Rodríguez, C. Rubio, M. Vera-Rodriguez, 2017, Fertility and sterility.

Optimizing the culture environment and embryo manipulation to help maintain embryo developmental potential.

M. Meseguer, C. Rubio, Gary D. Smith, 2016, Fertility and sterility.

Clinical Study New Tools for Embryo Selection : Comprehensive Chromosome Screening by Array Comparative Genomic Hybridization

A. Mercader, C. Rubio, Vanessa, 2015 .

New Tools for Embryo Selection: Comprehensive Chromosome Screening by Array Comparative Genomic Hybridization

V. Peinado, A. Mercader, C. Simón, 2014, BioMed research international.

Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis

M. Vera-Rodríguez, C. Simón, C. Rubio, 2015, Nature Communications.

Spontaneous in vitro maturation and artificial activation of human germinal vesicle oocytes recovered from stimulated cycles

A. Mercader, C. Rubio, A. Pellicer, 2011, Journal of Assisted Reproduction and Genetics.

ESHRE PGT Consortium data collection XVI–XVIII: cycles from 2013 to 2015†

C. Rubio, C. Rubio, C. Moutou, 2020, Human reproduction open.

ESHRE survey results and good practice recommendations on managing chromosomal mosaicism

J. Vermeesch, C. Rubio, A. Capalbo, 2022, Human reproduction open.

ESHRE PGT Consortium good practice recommendations for the detection of structural and numerical chromosomal aberrations

F. Spinella, C. Rubio, V. Goossens, 2020, Human reproduction open.

Mosaic human preimplantation embryos and their developmental potential in a prospective, non-selection clinical trial

C. Rubio, L. Rienzi, D. Cimadomo, 2021, American journal of human genetics.

A prospective double-blinded non-selection trial of reproductive outcomes and chromosomal normalcy of newborns derived from putative low/moderate-degree mosaic IVF embryos

A. Farcomeni, C. Simón, C. Rubio, 2021, medRxiv.

Mitochondrial DNA content as a viability score in human euploid embryos: less is better.

A. Diez-Juan, S. Martínez, D. Valbuena, 2015, Fertility and sterility.

PREIMPLANTATION GENETIC TESTING: Chromosome abnormalities in human embryos

C. Simón, C. Rubio, L. Rodrigo, 2020, Reproduction.

Impact of chromosomal abnormalities on preimplantation embryo development

A. Mercader, C. Simón, C. Rubio, 2007, Prenatal diagnosis.

Bisphenol A Effects on the Growing Mouse Oocyte Are Influenced by Diet1

P. Hunt, C. Rubio, T. Hassold, 2009, Biology of reproduction.

8 Human Male Meiosis and Sperm Aneuploidies

V. Peinado, C. Rubio, T. Hassold, 2018 .

Human Male Meiosis and Sperm Aneuploidies

V. Peinado, C. Rubio, T. Hassold, 2012 .

Aneuploidies in embryos and spermatozoa from patients with Y chromosome microdeletions.

V. Peinado, C. Rubio, J. Remohi, 2010, Fertility and sterility.

Impact of different patterns of sperm chromosomal abnormalities on the chromosomal constitution of preimplantation embryos.

V. Peinado, C. Simón, C. Rubio, 2010, Fertility and sterility.

Increased incidence of disomic sperm nuclei in a 47,XYY male assessed by fluorescent in situ hybridization (FISH)

C. Simón, C. Rubio, J. Egozcue, 1997, Human Genetics.

The impact of patient, embryo, and translocation characteristics on the ploidy status of young couples undergoing preimplantation genetic testing for structural rearrangements (PGT-SR) by next generation sequencing (NGS)

C. Rubio, L. Rodrigo, N. Findikli, 2021, Journal of Assisted Reproduction and Genetics.

High incidence of chromosomal abnormalities in large-headed and multiple-tailed spermatozoa.

C. Rubio, J. Remohi, A. Pellicer, 2006, Journal of andrology.

Clinical application of embryo aneuploidy testing by next-generation sequencing

V. Peinado, C. Simón, C. Rubio, 2019, Biology of Reproduction.

Molecular analysis of products of conception obtained by hysteroembryoscopy from infertile couples

C. Simón, C. Rubio, J. A. Martínez-Conejero, 2015, Journal of Assisted Reproduction and Genetics.

Moderate ovarian stimulation does not increase the incidence of human embryo chromosomal abnormalities in in vitro fertilization cycles.

C. Rubio, A. Pellicer, L. Rodrigo, 2012, The Journal of clinical endocrinology and metabolism.

Chromosomal Analysis of the Embryo: Preimplantation Genetic Screening

C. Rubio, 2014 .

The heparin-glutathione test: an alternative to the hypo-osmotic swelling test to select viable sperm for intracytoplasmic sperm injection.

C. Rubio, J. Tarín, F. Vendrell, 1998, Fertility and sterility.

Intracytoplasmic sperm injection (ICSI).

C. Rubio, M. J. de los Santos, A. Ruiz, 1997, Frontiers in bioscience : a journal and virtual library.

Reply: Hepatitis B virus in human oocytes and embryos

C. Rubio, N. Garrido, A. Pellicer, 2012 .

Cytological Studies of Human Meiosis: Sex-Specific Differences in Recombination Originate at, or Prior to, Establishment of Double-Strand Breaks

K. Broman, P. Hunt, C. Rubio, 2013, PloS one.

Embryo Aneuploidy Screening for Unexplained Recurrent Miscarriage: A Minireview

C. Simón, C. Rubio, J. Remohi, 2005, American journal of reproductive immunology.

Overcoming Challenges in Reproductive Health Applications by Deploying More Sensitive and Accurate Molecular Technologies

D. Behar, C. Rubio, C. Brasch-Andersen, 2019, EMJ Reproductive Health.

Chromosomal abnormalities in embryos from couples with a previous aneuploid miscarriage.

V. Peinado, C. Simón, C. Rubio, 2012, Fertility and sterility.

Heteroparental blastocyst production from microsurgically corrected tripronucleated human embryos.

D. Valbuena, C. Simón, C. Rubio, 2006, Fertility and sterility.

Self-correction in tripronucleated human embryos.

C. Rubio, A. Pellicer, M. Escribà, 2011, Fertility and sterility.

The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists.

J. Vermeesch, M. Meseguer, C. Simón, 2016, Molecular human reproduction.

Improved clinical utility of preimplantation genetic testing through the integration of ploidy and common pathogenic microdeletions analyses.

J. Jimenez-Almazan, C. Rubio, L. Rienzi, 2023, Human reproduction.

Embryonic Chromosomal Abnormalities Obtained After Rescue Intracytoplasmic Sperm Injection of 1-Day-Old Unfertilized Oocytes

C. Rubio, J. Remohi, A. Pellicer, 2004, Journal of Assisted Reproduction and Genetics.

False positive rate of an arrayCGH platform for single-cell preimplantation genetic screening and subsequent clinical application on day-3

V. Peinado, A. Mercader, C. Simón, 2012, Journal of Assisted Reproduction and Genetics.

mtDNA dynamics between cleavage-stage embryos and blastocysts

C. Rubio, B. Lawrenz, N. Garrido, 2019, Journal of Assisted Reproduction and Genetics.

Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos.

C. Simón, C. Rubio, L. Rienzi, 2020, American journal of human genetics.

Genome wide analysis of rare copy number variations in alcohol abuse or dependence.

J. Bobes, P. Sáiz, J. Costas, 2018, Journal of psychiatric research.

Distribution patterns of segmental aneuploidies in human blastocysts identified by next-generation sequencing.

Alex J. Bladon, F. Kokocinski, D. Blesa, 2016, Fertility and sterility.

Next-generation sequencing: challenges in reproductive genetics.

C. Rubio, 2014, Fertility and sterility.

Optimized NGS Approach for Detection of Aneuploidies and Mosaicism in PGT-A and Imbalances in PGT-SR

R. Navarro, C. Simón, C. Rubio, 2020, Genes.

The origin of biochemical pregnancies: lessons learned from preimplantation genetic diagnosis.

C. Rubio, A. Pellicer, E. Bosch, 2003, Fertility and sterility.

The morphokinetic signature of mosaic embryos: evidence in support of their own genetic identity.

A. Mercader, M. Meseguer, C. Rubio, 2021, Fertility and sterility.

Non-invasive PGT-A: An update

C. Rubio, C. García-Pascual, C. Simon, 2022, Reproductive BioMedicine Online.

Multicenter prospective study of concordance between embryo cell-free DNA and trophectoderm biopsies from 1,301 human blastocysts.

R. Navarro, D. Valbuena, C. Simón, 2020, American journal of obstetrics and gynecology.

Correlations between Synaptic Initiation and Meiotic Recombination: A Study of Humans and Mice.

K. Broman, P. Hunt, V. Peinado, 2016, American journal of human genetics.

Non-invasive preimplantation genetic testing for aneuploidies: an update.

C. Simón, C. Rubio, C. García-Pascual, 2022, Reproductive biomedicine online.

Noninvasive preimplantation genetic testing for aneuploidy: Is the glass half-empty or half-full?

C. Rubio, C. Simon, 2021, Fertility and sterility.

PGT-A (preimplantational genetic screening) in patients with partial X monosomy using own oocytes: is a suitable indication?

A. Mercader, M. Meseguer, C. Rubio, 2019, Fertility and Sterility.

Is there a relationship between time-lapse parameters and embryo sex?

M. Meseguer, C. Rubio, J. García-Velasco, 2015, Fertility and sterility.

Preimplantation Genetic Diagnosis by Fluorescence In Situ Hybridization: Clinical Possibilities and Pitfalls

C. Simón, C. Rubio, A. Pellicer, 2003, Journal of the Society for Gynecologic Investigation.

Noninvasive preimplantation genetic testing for aneuploidy in spent culture medium as a substitute for trophectoderm biopsy.

C. Rubio, C. Racowsky, D. Barad, 2021, Fertility and sterility.

Preimplantation Genetic Screening of Embryos for IVF

C. Rubio, J. Harper, 2019, How to Prepare the Egg and Embryo to Maximize IVF Success.

Preimplantation Genetic Diagnosis by Fluorescence In Situ Hybridiation: Clinical Possibliities and Pitfalls

C. Rubio, A. Pellicer, L. Rodrigo, 2003, Journal of the Society for Gynecologic Investigation.

Hepatitis B virus in human oocytes and embryos.

C. Rubio, J. Bellver, N. Garrido, 2012, Human reproduction.

The use of copy number loads to designate mosaicism in blastocyst stage PGT-A cycles: fewer is better.

R. Navarro, C. Rubio, A. Capalbo, 2023, Human reproduction.

Testing the mathematical model for PGT-A inefficiency with scientific sources demonstrates the efficacy of PGT-A.

C. Rubio, A. Capalbo, C. Simon, 2020, Human reproduction.

Clinical experience employing co-culture of human embryos with autologous human endometrial epithelial cells.

A. Mercader, C. Rubio, A. Pellicer, 2000, Human reproduction.

Non-invasive cell-free DNA-based approach for the diagnosis of clinical miscarriage: A retrospective study.

C. Rubio, L. Rodrigo, E. Mateu-Brull, 2023, BJOG : an international journal of obstetrics and gynaecology.

Chromosomal abnormalities and embryo development in recurrent miscarriage couples.

C. Rubio, C. Simón, C. Rubio, 2003, Human reproduction.

In vitro fertilization plus preimplantation genetic diagnosis in patients with recurrent miscarriage: an analysis of chromosome abnormalities in human preimplantation embryos.

C. Rubio, C. Simón, C. Rubio, 1999, Fertility and sterility.

Updates on preimplantation embryo research.

S. Bissière, C. Rubio, N. Plachta, 2023, Fertility and Sterility.

Cell-free DNA analysis in preimplantation genetic testing.

C. Rubio, C. García-Pascual, D. Bakalova, 2023, F&S Science.

Human embryo live imaging reveals nuclear DNA shedding during blastocyst expansion and biopsy

S. Bissière, C. Rubio, C. García-Pascual, 2023, Cell.

Increased chromosome abnormalities in human preimplantation embryos after in-vitro fertilization in patients with recurrent miscarriage.

C. Rubio, C. Simón, C. Rubio, 1998, Reproduction, fertility, and development.

Fertilization after intracytoplasmic sperm injection with cryopreserved testicular spermatozoa.

C. Rubio, C. Rubio, J. Remohi, 1996, Fertility and sterility.

Advanced paternal age does not affect embryo aneuploidy following blastocyst biopsy in egg donor cycles

C. Rubio, C. Cinnioğlu, R. Carrasquillo, 2019, Journal of Assisted Reproduction and Genetics.

The impact of endometriosis in couples undergoing intracytoplasmic sperm injection because of male infertility.

C. Rubio, C. Simón, C. Rubio, 1997, Human reproduction.

Origin and composition of cell-free DNA in spent medium from human embryo culture during preimplantation development

D. Blesa, M. Vera-Rodríguez, A. Diez-Juan, 2018, Human reproduction.

The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists.

J. Vermeesch, M. Meseguer, C. Simón, 2016, Molecular human reproduction.

mtDNA dynamics between cleavage-stage embryos and blastocysts

C. Rubio, B. Lawrenz, N. Garrido, 2019, Journal of Assisted Reproduction and Genetics.

The embryo mosaicism profile of next-generation sequencing PGT-A in different clinical conditions and their associations

C. Rubio, T. Ali, M. Riboldi, 2023, Frontiers in Reproductive Health.

Prospective cohort study in high responder oocyte donors using two hormonal stimulation protocols: impact on embryo aneuploidy and development.

A. Mercader, C. Rubio, A. Pellicer, 2010, Human reproduction.

Impact of preimplantation genetic diagnosis on IVF outcome in implantation failure patients.

C. Rubio, C. Simón, C. Rubio, 2003, Reproductive biomedicine online.