G. Booker

发表

Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase.

I. Campbell, G. Booker, A. Breeze, 1992, Nature.

Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance

L. Llewellyn, G. Booker, J. Carver, 2004, Peptides.

The subtle side to hypoxia inducible factor (HIFα) regulation

G. Booker, R. Bilton, 2003 .

The subtle side to hypoxia inducible factor (HIFalpha) regulation.

G. Booker, R. Bilton, 2003, European journal of biochemistry.

A Novel Approach to Identify Two Distinct Receptor Binding Surfaces of Insulin-like Growth Factor II*

G. Booker, J. Wallace, B. Forbes, 2009, Journal of Biological Chemistry.

Letter to the Editor: 1H, 13C and 15 N resonance assignments of the third spectrin repeat of α-actinin-4

G. Booker, A. L. Merkel, K. Kowalski, 2004 .

CBFA2T3-ZNF652 Corepressor Complex Regulates Transcription of the E-box Gene HEB*

G. Booker, P. Neilsen, D. Callen, 2008, Journal of Biological Chemistry.

Optimising in situ click chemistry: the screening and identification of biotin protein ligase inhibitors

G. Booker, M. Wilce, J. Wallace, 2013 .

An Investigation of the Ligand Binding Properties and Negative Cooperativity of Soluble Insulin-like Growth Factor Receptors*

K. Siddle, G. Booker, J. Wallace, 2008, Journal of Biological Chemistry.

The Rat Pyruvate Carboxylase Gene Structure

G. Booker, J. Wallace, A. Cassady, 1997, The Journal of Biological Chemistry.

Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR.

G. Booker, J. Wallace, A. Denley, 2004, Molecular endocrinology.

Production and characterization of monoclonal antibodies against insulin-like growth factor type 1 receptor.

G. Booker, J. Wallace, B. Forbes, 2006, Hybridoma.

The Solution Structure and Intramolecular Associations of the Tec Kinase Src Homology 3 Domain*

G. Booker, J. Mackay, M. Hinds, 2002, The Journal of Biological Chemistry.

Assignment of the 1H, 13C and 15N resonances of the calponin homology-2 domain of α-actinin-4

G. Booker, Huang-Hui Chen, Iain Murchland, 2008, Biomolecular NMR assignments.

A third fibronectin-type-III domain in the insulin-family receptors.

G. Booker, T. Mulhern, L. Cosgrove, 1998, Trends in biochemical sciences.

A novel molecular mechanism to explain biotin-unresponsive holocarboxylase synthetase deficiency

G. Booker, J. Wallace, S. Polyak, 2011, Journal of Molecular Medicine.

Inhibition of Mycobacterium tuberculosis Dethiobiotin Synthase (MtDTBS): Toward Next-Generation Antituberculosis Agents.

G. Booker, J. Bruning, A. P. Thompson, 2021, ACS chemical biology.

Conserved Glu40 and Glu433 of the biotin carboxylase domain of yeast pyruvate carboxylase I isoenzyme are essential for the association of tetramers.

G. Booker, W. Cleland, J. Wallace, 2007, The international journal of biochemistry & cell biology.

A template guided approach to generating cell permeable inhibitors of Staphylococcus aureus biotin protein ligase

G. Booker, M. Cooper, A. Abell, 2017 .

New Series of BPL Inhibitors To Probe the Ribose-Binding Pocket of Staphylococcus aureus Biotin Protein Ligase.

G. Booker, A. Abell, William Tieu, 2016, ACS medicinal chemistry letters.

Selective inhibition of Biotin Protein Ligase from Staphylococcus aureus*

G. Booker, J. Turnidge, N. R. Pendini, 2012, The Journal of Biological Chemistry.

Identification and functional characterization of two novel mutations in the α‐helical loop (residues 484–503) of CYBB/gp91phox resulting in the rare X91+ variant of chronic granulomatous disease

S. Choo, Joanne M. Smart, G. Booker, 2012, Human mutation.

A Novel Tool for Studying Auxin-Metabolism: The Inhibition of Grapevine Indole-3-Acetic Acid-Amido Synthetases by a Reaction Intermediate Analogue

G. Booker, P. Boss, C. Davies, 2012, PloS one.

Cloning, sequencing and expression of rat liver pyruvate carboxylase.

G. Booker, J. Wallace, A. Cassady, 1996, The Biochemical journal.

Biotin-mediated growth and gene expression in Staphylococcus aureus is highly responsive to environmental biotin

G. Booker, K. Shearwin, J. Satiaputra, 2018, Applied Microbiology and Biotechnology.

Sulfonamide-based inhibitors of biotin protein ligase as new antibiotic leads.

G. Booker, M. Wilce, J. Bruning, 2019, ACS chemical biology.

Biotin Protein Ligase Is a Target for New Antibacterials

G. Booker, A. Abell, S. Polyak, 2016, Antibiotics.

Dual roles of F123 in protein homodimerization and inhibitor binding to biotin protein ligase from Staphylococcus aureus

G. Booker, Matthew C.J. Wilce, M. Perugini, 2014, Molecular microbiology.

Improved Synthesis of Biotinol-5'-AMP: Implications for Antibacterial Discovery.

R. Lumb, G. Booker, J. Turnidge, 2015, ACS medicinal chemistry letters.

Heterocyclic acyl-phosphate bioisostere-based inhibitors of Staphylococcus aureus biotin protein ligase.

G. Booker, J. Wallace, A. Abell, 2014, Bioorganic & medicinal chemistry letters.

Purification, crystallization and preliminary crystallographic analysis of biotin protein ligase from Staphylococcus aureus.

G. Booker, N. R. Pendini, M. Wilce, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure of an SH2 domain of the p85α subunit of phosphatidylinositol-3-OH kinase

I. Campbell, G. Booker, A. Breeze, 1994, Nature.

Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase.

G. Booker, J. Bruning, A. P. Thompson, 2018, Acta crystallographica. Section D, Structural biology.

Synthesis of 5-, 6- and 7-substituted-2-aminoquinolines as SH3 domain ligands.

G. Booker, S. Pyke, D. Fritz, 2005, Organic & biomolecular chemistry.

Splice variants of the mouse Tec gene are differentially expressed in vivo

A. Merkel, G. Booker, P. Rathjen, 1999, Cytogenetic and Genome Research.

Assignment of 1H and 15N resonances of murine Tec SH3 domain

G. Booker, R. Norton, M. Hinds, 1998, Journal of biomolecular NMR.

Mechanisms of biotin-regulated gene expression in microbes

G. Booker, K. Shearwin, J. Satiaputra, 2016, Synthetic and systems biotechnology.

Synthesis of N-benzylated-2-aminoquinolines as ligands for the Tec SH3 domain.

G. Booker, S. Pyke, S. Inglis, 2006, Bioorganic & medicinal chemistry letters.

Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus.

G. Booker, M. Wilce, A. Abell, 2017, ACS infectious diseases.

Identification and specificity studies of small-molecule ligands for SH3 protein domains.

Daniel Fritz, G. Booker, S. Pyke, 2004, Journal of medicinal chemistry.

Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes

G. Booker, J. Bruning, A. P. Thompson, 2018, ACS Catalysis.

5-benzylidenerhodanine and 5-benzylidene-2-4-thiazolidinedione based antibacterials.

G. Booker, A. Abell, R. Morona, 2012, Bioorganic & medicinal chemistry letters.

Identification and targeted management of a neurodegenerative disorder caused by biallelic mutations in SLC5A6

G. Booker, K. Kassahn, J. Fletcher, 2019, npj Genomic Medicine.

Microbial biotin protein ligases aid in understanding holocarboxylase synthetase deficiency.

G. Booker, N. R. Pendini, M. Wilce, 2008, Biochimica et biophysica acta.

Mechanisms of Biotin Transport

G. Booker, S. Polyak, A. Azhar, 2015 .

Mechanisms Governing Precise Protein Biotinylation.

G. Booker, J. Bruning, K. Wegener, 2017, Trends in biochemical sciences.

Precise mapping of an IGF-I-binding site on the IGF-1R.

G. Booker, J. Wallace, B. Forbes, 2007, The Biochemical journal.

Molecular interactions of the IGF system.

G. Booker, J. Wallace, A. Denley, 2005, Cytokine & growth factor reviews.

The Role of Biotin in Bacterial Physiology and Virulence: a Novel Antibiotic Target for Mycobacterium tuberculosis.

G. Booker, S. Polyak, W. Salaemae, 2016, Microbiology spectrum.

The GTPase dynamin binds to and is activated by a subset of SH3 domains

I. Campbell, G. Booker, G. Panayotou, 1993, Cell.

New insights into protein‐tyrosine kinase receptor signaling complexes

G. Booker, G. Panayotou, M. Waterfield, 1993, Protein science : a publication of the Protein Society.

Solution structure and ligand-binding site of the SH3 domain of the p85α subunit of phosphatidylinositol 3-kinase

I. Campbell, G. Booker, I. Gout, 1993, Cell.

Biochemical characterisation of class III biotin protein ligases from Botrytis cinerea and Zymoseptoria tritici.

G. Booker, N. R. Pendini, P. Barran, 2020, Archives of biochemistry and biophysics.

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit.

Anna L. Brown, G. Booker, Angel F. Lopez, 2010, Blood.

The solution structure of the cytokine-binding domain of the common beta-chain of the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5.

M. Vadas, G. Booker, T. Mulhern, 2000, Journal of molecular biology.

Differential activation of insulin receptor isoforms by insulin-like growth factors is determined by the C domain.

G. Booker, C. Roberts, J. Wallace, 2006, Endocrinology.

Biotin protein ligase from Candida albicans: expression, purification and development of a novel assay.

G. Booker, N. R. Pendini, M. Wilce, 2008, Archives of biochemistry and biophysics.

Native mass spectrometry identifies an alternative DNA-binding pathway for BirA from Staphylococcus aureus

G. Booker, T. Pukala, K. Shearwin, 2019, Scientific Reports.

Native mass spectrometry identifies an alternative DNA-binding pathway for BirA from Staphylococcus aureus

G. Booker, T. Pukala, K. Shearwin, 2019, Scientific Reports.

Structural characterization of Staphylococcus aureus biotin protein ligase and interaction partners: An antibiotic target

G. Booker, N. R. Pendini, N. Cowieson, 2013, Protein science : a publication of the Protein Society.

Substrate Requirements of the Oxygen-sensing Asparaginyl Hydroxylase Factor-inhibiting Hypoxia-inducible Factor*

G. Booker, D. Peet, M. Whitelaw, 2004, Journal of Biological Chemistry.

Structure, function and selective inhibition of bacterial acetyl-coa carboxylase

G. Booker, M. Wilce, A. Abell, 2011, Applied Microbiology and Biotechnology.

Localization of inhibitory antibodies to the biotin domain of human pyruvate carboxylase.

G. Booker, J. Wallace, S. Polyak, 2012, Hybridoma.

AqF026 is a pharmacologic agonist of the water channel aquaporin-1.

G. Booker, J. Verbavatz, O. Devuyst, 2013, Journal of the American Society of Nephrology : JASN.

Phosphopeptide binding to the N‐terminal SH2 domain of the p85α subunit of PI 3′‐kinase: A heteronuclear NMR study

I. Campbell, G. Booker, G. Panayotou, 1994, Protein science : a publication of the Protein Society.

Advanced Resistance Studies Identify Two Discrete Mechanisms in Staphylococcus aureus to Overcome Antibacterial Compounds that Target Biotin Protein Ligase

G. Booker, T. Pukala, K. Shearwin, 2020, Antibiotics.

Structure guided design of biotin protein ligase inhibitors for antibiotic discovery.

G. Booker, M. Wilce, A. Abell, 2013, Current topics in medicinal chemistry.

Letter to the Editor: 1H and 15N chemical shift assignments for domain 4 of the common β-chain of the IL-3, IL-5 and GM-CSF receptors

M. Vadas, G. Booker, T. Mulhern, 1999 .

Escherichia coli biotin protein ligase: characterization and development of a high-throughput assay.

G. Booker, J. Wallace, S. Polyak, 2008, Analytical biochemistry.

In silico screening and biological evaluation of inhibitors of Src-SH3 domain interaction with a proline-rich ligand.

G. Booker, C. Dive, R. Bryce, 2008, Bioorganic & medicinal chemistry letters.

Biotin analogues with antibacterial activity are potent inhibitors of biotin protein ligase.

G. Booker, J. Turnidge, M. Wilce, 2012, ACS medicinal chemistry letters.

Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase.

I. Campbell, G. Booker, A. Downing, 1993, Cell.

Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochemistry and molecular intervention

G. Booker, S. Polyak, W. Salaemae, 2011, Protein & Cell.

A novel molecular mechanism to explain biotin-unresponsive holocarboxylase synthetase deficiency

G. Booker, J. Wallace, S. Polyak, 2011, Journal of Molecular Medicine.

Understanding the Mechanism of Insulin and Insulin-Like Growth Factor (IGF) Receptor Activation by IGF-II

G. Booker, J. Wallace, B. Forbes, 2011, PloS one.

Sequential and selective Buchwald-Hartwig amination reactions for the controlled functionalization of 6-bromo-2-chloroquinoline: synthesis of ligands for the Tec Src homology 3 domain.

G. Booker, S. Pyke, Jessica A. Smith, 2008, The Journal of organic chemistry.

Tuberculosis control in Jiangsu province, China

G. Booker, S. Polyak, Y. Hao, 2016 .

Structure, function and selective inhibition of bacterial acetyl-coa carboxylase

G. Booker, M. Wilce, A. Abell, 2012, Applied Microbiology and Biotechnology.

Anuran host-defense peptides that complex with Ca2+ calmodulin and inhibit the synthesis of the cell signalling agent nitric oxide by neuronal nitric oxide synthase

L. Llewellyn, G. Booker, T. Pukala, 2009 .

The key position: influence of staple location on constrained peptide conformation and binding.

G. Booker, A. Abell, K. Wegener, 2016, Organic & biomolecular chemistry.

The Role of Biotin in Bacterial Physiology and Virulence: a Novel Antibiotic Target for Mycobacterium tuberculosis

G. Booker, S. Polyak, W. Salaemae, 2016, Microbiology spectrum.