M. Lan

发表

Human arm weight compensation in rehabilitation robotics: efficacy of three distinct methods

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2020, Journal of NeuroEngineering and Rehabilitation.

Additional file 3

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2012 .

The Transcription Factor Encyclopedia

Debra L. Fulton, Henriette O'Geen, Elodie Portales-Casamar, 2012, Genome Biology.

Detection of neuroendocrine tumors using promoter-specific secreted Gaussia luciferase.

M. Breslin, M. Lan, A. Tseng, 2016, International journal of oncology.

IA-2, a transmembrane protein tyrosine phosphatase, is expressed in human lung cancer cell lines with neuroendocrine phenotype.

M. Lan, A. Notkins, H. Xie, 1996, Cancer Research.

Identification of three genomic haplotypes 5' to the human CD1D gene and their distribution in four ethnic groups.

Q. Y. Chen, M. Batzer, M. Lan, 2003, Tissue antigens.

Coupling of glucose response element from L-type pyruvate kinase and G6Pase promoter enhances glucose responsive activity in hepatoma cells

M. Breslin, M. Lan, Hong-wei Wang, 2007, Molecular and Cellular Biochemistry.

Immunological heterogeneity in Type I diabetes: presence of distinct autoantibody patterns in patients with acute onset and slowly progressive disease

R. Heine, W. Scherbaum, N. Morgenthaler, 1998, Diabetologia.

Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequence.

M. Breslin, M. Lan, A. Notkins, 2002, Nucleic acids research.

INSM1 increases N-myc stability and oncogenesis via a positive-feedback loop in neuroblastoma

M. Breslin, M. Lan, Chiachen Chen, 2015, Oncotarget.

INSM1 promoter-driven adenoviral herpes simplex virus thymidine kinase cancer gene therapy for the treatment of primitive neuroectodermal tumors.

M. Breslin, M. Lan, Hong-wei Wang, 2009, Human gene therapy.

Cloning and sequencing of a human pancreatic tumor mucin cDNA.

S. Batra, M. Lan, M. Hollingsworth, 1990, The Journal of biological chemistry.

Value of Antibodies to Islet Protein Tyrosine Phosphatase–Like Molecule in Predicting Type 1 Diabetes

M. Lan, P. Pozzilli, R. Leslie, 1997, Diabetes.

Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells.

M. Lan, T. Reh, B. Nelson, 2007, Developmental biology.

Insulinoma-Associated-1: From Neuroendocrine Tumor Marker to Cancer Therapeutics

M. Lan, A. Notkins, Chiachen Chen, 2019, Molecular Cancer Research.

Tumor-specific promoter-driven adenoviral therapy for insulinoma

M. Breslin, M. Lan, A. Tseng, 2016, Cellular Oncology.

Characterization and chromosomal localization of a new protein disulfide isomerase, PDIp, highly expressed in human pancreas.

M. Lan, W. Modi, G. Donadel, 1996, DNA and cell biology.

An effective alternate cloning strategy for unstable mouse genomic sequences.

M. Lan, Michelle Muguira, 2005, Biochemical and Biophysical Research Communications - BBRC.

The human leukocyte antigen HLA DRB3*020/DQA1*0501 haplotype is associated with Graves' disease in African Americans.

M. Lan, Y. Tomer, N. Maclaren, 2000, The Journal of clinical endocrinology and metabolism.

Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment.

M. Lan, N. Maclaren, A. Notkins, 1996, Proceedings of the National Academy of Sciences of the United States of America.

IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.

M. Lan, N. Maclaren, C. Wasserfall, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Targeted disruption of the protein tyrosine phosphatase-like molecule IA-2 results in alterations in glucose tolerance tests and insulin secretion.

M. Lan, A. Kubosaki, K. Saeki, 2002, Diabetes.

Autoantibodies against IA-2, GAD, and topoisomerase II in type 1 diabetic patients.

M. Lan, S. Tsai, Yih-Hsin Chang, 2004, Biochemical and biophysical research communications.

Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential

M. Lan, D. Lu, Xin Gao, 2008, Diabetologia.

Functional role of an islet transcription factor, INSM1/IA‐1, on pancreatic acinar cell trans‐differentiation

M. Breslin, M. Lan, Nicolle A Saunée, 2012, Journal of cellular physiology.

Expression of a Novel Zinc-Finger cDNA, IA-1, Is Associated with Rat AR42J Cells Differentiation into Insulin-Positive Cells

M. Breslin, M. Lan, Min Zhu, 2002, Pancreas.

Comparison of IA-2 with IA-2beta and with six other members of the protein tyrosine phosphatase family: recognition of antigenic determinants by IDDM sera.

M. Lan, A. Notkins, Y. Matsumoto, 1997, Journal of Autoimmunity.

Co‐expression of human cancer‐associated epitopes on mucin molecules

R. Bast, R. Knapp, M. Lan, 1987, International journal of cancer.

Functional Domains of Autoimmune Regulator (AIRE) Modulate INS-VNTR Transcription in Human Thymic Epithelial Cells*

M. Breslin, M. Lan, Chiachen Chen, 2016, Journal of Biological Chemistry.

The zinc-finger transcription factor INSM1 is expressed during embryo development and interacts with the Cbl-associated protein.

M. Lan, T. Cai, A. Notkins, 2002, Genomics.

Isolation and properties of a human pancreatic adenocarcinoma-associated antigen, DU-PAN-2.

M. Lan, R. Metzgar, O. Finn, 1985, Cancer Research.

Both Polymorphic VNTR and AIRE Modulate Differential Expression of Insulin in Human Thymic Epithelial Cells

M. Breslin, M. Lan, M. Giraud, 2010 .

The relationship between humoral and cellular immunity to IA-2 in IDDM.

J. She, M. Lan, M. Atkinson, 1998, Diabetes.

5′-Iodotubercidin represses insulinoma-associated-1 expression, decreases cAMP levels, and suppresses human neuroblastoma cell growth

M. Breslin, M. Lan, J. Guidry, 2019, Journal of Biological Chemistry.

Expression of biologically active TAT-fused recombinant islet transcription factors.

M. Breslin, M. Lan, Nicolle A Saunée, 2014, Life sciences.

Molecular characterization of a mucin-type antigen associated with human pancreatic cancer. The DU-PAN-2 antigen.

M. Lan, R. Metzgar, A. Khorrami, 1987, The Journal of biological chemistry.

Pax4 paired domain mediates direct protein transduction into mammalian cells.

M. Lan, Hongwei Wang, Shuyu Zhang, 2007, Endocrinology.

Pdx-1 Modulates Histone H4 Acetylation and Insulin Gene Expression in Terminally Differentiated &agr;-TC-1 Cells

M. Breslin, M. Lan, Hong-wei Wang, 2007, Pancreas.

The Transcription Factor Encyclopedia The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2012 .

Islet cell autoimmunity in youth onset diabetes mellitus in Northern India.

M. Lan, R. Goswami, N. Maclaren, 2001, Diabetes research and clinical practice.

Assignment of the IA-2 gene encoding an autoantigen in IDDM to chromosome 2q35

M. Lan, 1996, Diabetologia.

Ectopic expression of a small cell lung cancer transcription factor, INSM1 impairs alveologenesis in lung development

M. Breslin, M. Lan, Chiachen Chen, 2016, BMC Pulmonary Medicine.

Materials and methods for detection and treatment of insulin-dependent diabetes

M. Lan, N. Maclaren, A. Notkins, 1997 .

Ia-2 and IA-2β : The immune response in IDDM

M. Lan, R. Leslie, A. Notkins, 1998 .

IA-2 and IA-2beta: the immune response in IDDM.

M. Lan, R. Leslie, A. Notkins, 1998, Diabetes Metabolism Reviews.

Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells.

M. Lan, R. Metzgar, D. Barnd, 1989, Proceedings of the National Academy of Sciences of the United States of America.

IA-2 and IA-2 beta are major autoantigens in IDDM and the precursors of the 40 kDa and 37 kDa tryptic fragments.

M. Lan, N. Maclaren, C. Wasserfall, 1996, Journal of autoimmunity.

Modifications to the INSM1 promoter to preserve specificity and activity for use in adenoviral gene therapy of neuroendocrine carcinomas

M. Breslin, M. Lan, V. Akerstrom, 2012, Cancer Gene Therapy.

Extra-nuclear activity of INSM1 transcription factor enhances insulin receptor signaling pathway and Nkx6.1 expression through RACK1 interaction.

M. Breslin, M. Lan, K. Song, 2014, Cellular signalling.

Molecular Cloning and Characterization of a Highly Basic Protein, IA-4, Expressed in Pancreatic Islets and Brain

M. Lan, G. Donadel, A. Notkins, 1998, Neuroendocrinology.

Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance

M. Lan, Zhongsheng Sun, Guanjie Chen, 2018, Journal of Translational Medicine.

Isolation and Properties of a Human Pancreatic Adenocarcinoma-associated Antigen, DU-PAN-21

M. Lan, R. Metzgar, O. Finn, 2006 .

Aberrant expression of monoclonal antibody-defined colonic mucosal antigens in inflammatory bowel disease.

M. Lan, M. Borowitz, R. Metzgar, 1988, Gastroenterology.

Autoantibodies to IA-2 in IDDM: Location of Major Antigenic Determinants

M. Lan, A. Notkins, B. Zhang, 1997, Diabetes.

The pancreas-specific protein disulphide-isomerase PDIp interacts with a hydroxyaryl group in ligands.

M. Lan, L. Ruddock, G. Robinson, 2001, Biochemical Journal.

L-arginine regulates the expression of the T-cell receptor ζ chain (CD3ζ) in Jurkat cells

M. Lan, J. Ochoa, A. Ochoa, 2001 .

Interplay: The Essential Role between INSM1 and N-Myc in Aggressive Neuroblastoma

M. Lan, Chiachen Chen, 2022, Biology.

Neurogenin 3 recruits CBP co‐activator to facilitate histone H3/H4 acetylation in the target gene INSM1

M. Breslin, M. Lan, Hong-wei Wang, 2007, FEBS letters.

Autoantibodies to IA-2 not detected in NOD mice or BB rats

M. Lan, H. Jun, A. Notkins, 1996, Diabetologia.

Genomic organization, 5'-upstream sequence, and chromosomal localization of an insulinoma-associated intronless gene, IA-1.

M. Lan, W. Modi, A. Notkins, 1994, The Journal of biological chemistry.

Isolation, sequence and expression of a novel mouse brain cDNA, mIA-2, and its relatedness to members of the protein tyrosine phosphatase family.

M. Lan, A. Notkins, J. Lu, 1994, Biochemical and biophysical research communications.

A promoter-driven assay for INSM1-associated signaling pathway in neuroblastoma.

M. Lan, Chiachen Chen, 2020, Cellular signalling.

Genomic structure and promoter sequence of the insulin-dependent diabetes mellitus autoantigen, IA-2 (PTPRN).

M. Lan, A. Notkins, B. Zhang, 1998, Genomics.

Detection of a pancreatic cancer-associated antigen (DU-PAN-2 antigen) in serum and ascites of patients with adenocarcinoma.

W. Meyers, R. Sandler, M. Lan, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Detection of an oncofetal antigen (DU‐PAN‐2) in sera of patients with non‐malignant hepatobiliary diseases and hepatomas

M. Lan, M. Borowitz, R. Metzgar, 1988, International journal of cancer.

The gene responsible for autoimmune polyglandular syndrome type 1 maps to chromosome 21q22.3 in US patients.

M. Lan, N. Maclaren, J. She, 1998, Journal of Autoimmunity.

Both Polymorphic Variable Number of Tandem Repeats and Autoimmune Regulator Modulate Differential Expression of Insulin in Human Thymic Epithelial Cells

M. Breslin, M. Lan, M. Giraud, 2010, Diabetes.

Mapping to Chromosomes 1 and 12 of mouse homologs of human protein tyrosine phosphatase, receptor-type, related genes encoding pancreatic beta cell autoantigens

M. Lan, E. Leiter, A. Notkins, 1997, Mammalian Genome.

Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance

M. Lan, Zhongsheng Sun, Guanjie Chen, 2018, Journal of Translational Medicine.

Expression of insulinoma-associated 2 (INSM2) in pancreatic islet cells is regulated by the transcription factors Ngn3 and NeuroD1.

M. Lan, T. Cai, A. Notkins, 2011, Endocrinology.

IA1 is NGN3‐dependent and essential for differentiation of the endocrine pancreas

R. F. Luco, M. Lan, D. Pipeleers, 2006, The EMBO journal.

Molecular characterization of the promoter region of a neuroendocrine tumor marker, IA-1.

M. Lan, A. Notkins, Q. Li, 1997, Biochemical and biophysical research communications.

Zinc Finger Transcription Factor INSM1 Interrupts Cyclin D1 and CDK4 Binding and Induces Cell Cycle Arrest*

M. Breslin, M. Lan, Nicolle A Saunée, 2009, Journal of Biological Chemistry.

INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases.

M. Breslin, M. Lan, Hong-wei Wang, 2006, The Biochemical journal.

IA-1, a new marker for neuroendocrine differentiation in human lung cancer cell lines.

M. Lan, E. Russell, B. Johnson, 1993, Cancer research.

[Corrigendum] Leptin stimulates ovarian cancer cell growth and inhibits apoptosis by increasing cyclin D1 and Mcl-1 expression via the activation of the MEK/ERK1/2 and PI3K/Akt signaling pathways.

M. Breslin, M. Lan, Chiachen Chen, 2013, International journal of oncology.

Leptin stimulates ovarian cancer cell growth and inhibits apoptosis by increasing cyclin D1 and Mcl-1 expression via the activation of the MEK/ERK1/2 and PI3K/Akt signaling pathways.

M. Breslin, M. Lan, Chiachen Chen, 2013, International Journal of Oncology.

Profile and Differential Expression of Protein Tyrosine Phosphatases in Mouse Pancreatic Islet Tumor Cell Lines

M. Lan, G. Donadel, A. Notkins, 1998, Pancreas.

Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology

M. Lan, A. McKee, P. Eisenhauer, 2004, Brain Research.

Immunization therapies in the prevention of diabetes.

M. Lan, N. Maclaren, C. Wasserfall, 1997, Journal of Autoimmunity.

Comparative analysis of the transduction efficiency of five adeno associated virus serotypes and VSV-G pseudotype lentiviral vector in lung cancer cells

M. Breslin, M. Lan, V. Akerstrom, 2013, Virology Journal.

Molecular characterization of a pancreas-specific protein disulfide isomerase, PDIp.

M. Lan, A. Notkins, M. Desilva, 1997, DNA and cell biology.

HERV-K10s and Immune-Mediated (Type 1) Diabetes

M. Lan, R. Garry, N. Maclaren, 1998, Cell.

Polypeptide core of a human pancreatic tumor mucin antigen.

M. Lan, M. Hollingsworth, R. Metzgar, 1990, Cancer research.

Structure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation

M. Breslin, M. Lan, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A novel human insulinoma-associated cDNA, IA-1, encodes a protein with "zinc-finger" DNA-binding motifs.

M. de Silva, M. Lan, A. Toscani, 1992, The Journal of biological chemistry.

Additional file 7

Debra L. Fulton, Wyeth W. Wasserman, Philip Bradley, 2012 .

Insulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation.

M. Breslin, M. Lan, Hongwei Wang, 2010, Endocrinology.

Autoantibodies to IA-2 and IA-2 beta in insulin-dependent diabetes mellitus recognize conformational epitopes: location of the 37- and 40-kDa fragments determined.

M. Lan, A. Notkins, Y. Matsumoto, 1997, Journal of immunology.

cDNA sequence and genomic organization of mouse secretin.

W. Kajiyama, M. Lan, G. Donadel, 1994, Biochemical and biophysical research communications.

The insulinoma-associated 1: a novel promoter for targeted cancer gene therapy for small-cell lung cancer

M. Breslin, M. Lan, N. Pedersen, 2006, Cancer Gene Therapy.

Hypermethylation of hepatic glucokinase and L-type pyruvate kinase promoters in high-fat diet-induced obese rats.

M. Lan, D. Lu, Xin Gao, 2011, Endocrinology.

L-Arginine regulates the expression of the T-cell receptor zeta chain (CD3zeta) in Jurkat cells.

M. Lan, H. Park, J. Ochoa, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Multiple autoantibodies as predictors of Type 1 diabetes in a general population

J. Krischer, M. Lan, N. Maclaren, 2003, Diabetologia.

Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma.

M. Lan, A. Notkins, J. Lu, 1994, DNA and cell biology.

Sonic hedgehog signaling pathway promotes INSM1 transcription factor in neuroendocrine lung cancer.

M. Breslin, M. Lan, Chiachen Chen, 2018, Cellular signalling.

Human CD1D Gene Expression Is Regulated by LEF-1 through Distal Promoter Regulatory Elements

M. Lan, S. Pincus, N. Maclaren, 2010, The Journal of Immunology.

Regulatory Elements by LEF-1 through Distal Promoter Human CD 1 D Gene Expression Is Regulated and

M. Lan, S. Pincus, N. Maclaren, 2010 .

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription.

M. Breslin, M. Lan, Hong-wei Wang, 2008, The Journal of endocrinology.

NeuroD1/E47 Regulates the E-box Element of a Novel Zinc Finger Transcription Factor, IA-1, in Developing Nervous System*

M. Breslin, M. Lan, Min Zhu, 2003, Journal of Biological Chemistry.

Tumor-specific promoter-driven adenoviral therapy for insulinoma

M. Breslin, M. Lan, A. Tseng, 2016, Cellular Oncology.

DU-PAN-2, mucin type differentiation antigen of normal and malignant pancreatic ductal cells.

M. Lan, M. Hollingsworth, R. Metzgar, 1989, Progress in clinical and biological research.

Comparative analysis of the transduction efficiency of five adeno associated virus serotypes and VSV-G pseudotype lentiviral vector in lung cancer cells

M. Breslin, M. Lan, V. Akerstrom, 2013, Virology Journal.

Adenoviral insulinoma-associated protein 1 promoter-driven suicide gene therapy with enhanced selectivity for treatment of neuroendocrine cancers.

M. Breslin, M. Lan, V. Akerstrom, 2013, The Ochsner journal.

Cryptic epitope and autoimmunity.

M. Lan, N. Maclaren, 1998, Diabetes/metabolism reviews.

Repurposing a plant alkaloid homoharringtonine targets insulinoma associated-1 in N-Myc-activated neuroblastoma.

M. Lan, C. Hicks, Chiachen Chen, 2023, Cellular signalling.

328. Transcriptionally Targeted Cancer Gene Therapy for Small Cell Lung Cancer

M. Breslin, M. Lan, N. Pedersen, 2006 .

Small Molecules Targeting INSM1 for the Treatment of High-Risk Neuroblastoma

M. Lan, Chiachen Chen, 2023, Biology.

Recombinant MafA protein containing its own protein transduction domain stimulates insulin gene expression in IEC-6 cells.

M. Lan, D. Lu, Hui-ling Wu, 2011, Life sciences.

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription.

M. Breslin, M. Lan, Hong-wei Wang, 2008, The Journal of endocrinology.

Regulatory Elements by LEF-1 through Distal Promoter Human CD1D Gene Expression Is Regulated

M. Lan, S. Pincus, N. Maclaren, 2017 .

Defective Morphogenesis and Functional Maturation in Fetal Islet-Like Cell Clusters From OLETF Rat, A Model of NIDDM

M. Lan, T. Murakami, A. Mizuno, 2001, International journal of experimental diabetes research.