D. Peet

发表

Human arm weight compensation in rehabilitation robotics: efficacy of three distinct methods

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2020, Journal of NeuroEngineering and Rehabilitation.

Additional file 3

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2012 .

The Transcription Factor Encyclopedia

Debra L. Fulton, Henriette O'Geen, Elodie Portales-Casamar, 2012, Genome Biology.

Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch

D. Peet, M. Whitelaw, D. Lando, 2002, Science.

Turn me on: regulating HIF transcriptional activity

D. Peet, K. Lisy, 2008, Cell Death and Differentiation.

Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1

R. Wenger, D. Peet, W. Wolski, 2019, Redox biology.

Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2.

A. E. Sullivan, P. Froguel, D. Peet, 2014, The Biochemical journal.

bHLH–PAS proteins in cancer

Daniel J. Peet, A. E. Sullivan, D. Peet, 2013, Nature Reviews Cancer.

Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR.

D. Corey, D. Peet, D. Mangelsdorf, 1998, Chemistry & biology.

Asparagine hydroxylation is likely to be a reversible post-translational modification

L. K. Nguyen, A. von Kriegsheim, D. Peet, 2020, bioRxiv.

Asparagine Hydroxylation is a Reversible Post-translational Modification

L. K. Nguyen, A. von Kriegsheim, D. Peet, 2020, Molecular & Cellular Proteomics.

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.

D. Peet, M. Whitelaw, D. Lando, 2002, Genes & development.

When is a target not a target?

D. Peet, D. Bersten, 2019, eLife.

Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway

D. Peet, A. Mercer, J. Gorman, 2016, Journal of Virology.

Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel

D. Peet, M. Dallas, Johana Chicher, 2015, Journal of Cell Science.

The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism.

D. Peet, L. Poellinger, G. Haddad, 2010, Cell metabolism.

From Polyps to People

D. Peet, R. J. Hampton-Smith, R.J. Hampton‐Smith, 2009, Annals of the New York Academy of Sciences.

Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).

D. Peet, Johana Chicher, J. Gorman, 2009, The international journal of biochemistry & cell biology.

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

U. Lendahl, D. Peet, L. Poellinger, 2008, Proceedings of the National Academy of Sciences.

Hypoxia Inducible Factor

D. Peet, R. J. Hampton-Smith, Rachel J. Hampton-Smith, 2007 .

Characterization of ankyrin repeat-containing proteins as substrates of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible transcription factor.

D. Peet, S. Linke, R. J. Hampton-Smith, 2007, Methods in enzymology.

Oxygen-dependent asparagine hydroxylation.

D. Peet, M. Whitelaw, D. Lando, 2004, Methods in enzymology.

Defining the Role for XAP2 in Stabilization of the Dioxin Receptor*

D. Peet, M. Whitelaw, M. Lees, 2003, Journal of Biological Chemistry.

Activity of Hypoxia-inducible Factor 2α Is Regulated by Association with the NF-κB Essential Modulator*

C. Bracken, D. Peet, M. Whitelaw, 2005, Journal of Biological Chemistry.

Oxygen-regulated gene expression in murine cumulus cells.

D. Peet, D. Russell, K. Kind, 2015, Reproduction, fertility, and development.

Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells

A. Zannettino, A. Harris, D. Peet, 2010, Haematologica.

Modulation of TRP Channel Activity by Hydroxylation and Its Therapeutic Potential

D. Peet, Yagnesh Nagarajan, G. Rychkov, 2017, Pharmaceuticals.

Regulation of gene expression by the hypoxia-inducible factors.

D. Peet, M. Whitelaw, A. Fedele, 2002, Molecular interventions.

Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment.

C. Bracken, D. Peet, M. Whitelaw, 2006, The Journal of biological chemistry.

HIF-2α Promotes Dissemination of Plasma Cells in Multiple Myeloma by Regulating CXCL12/CXCR4 and CCR1.

K. Mrozik, C. Cheong, A. Zannettino, 2017, Cancer research.

Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes

D. Peet, J. Bruning, M. Whitelaw, 2022, The Biochemical journal.

The Transcription Factor Encyclopedia The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2012 .

Regulation of HIF: asparaginyl hydroxylation.

D. Peet, S. Linke, 2006, Novartis Foundation symposium.

Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα

R. Hammer, D. Peet, D. Mangelsdorf, 1998, Cell.

The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma

A. Zannettino, D. Peet, S. Gronthos, 2011, Leukemia.

Human Variants in the Neuronal Basic Helix-Loop-Helix/Per-Arnt-Sim (bHLH/PAS) Transcription Factor Complex NPAS4/ARNT2 Disrupt Function

D. Peet, J. Bruning, M. Whitelaw, 2014, PloS one.

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features.

Beverley Balkau, Philippe Froguel, David Meyre, 2013, The Journal of clinical investigation.

Rare variants in single-minded 1 (SIM1) are associated with severe obesity.

Mehul Dattani, Sumedha Garg, Soren Brage, 2013, The Journal of clinical investigation.

The conservation and functionality of the oxygen-sensing enzyme Factor Inhibiting HIF (FIH) in non-vertebrates

D. Peet, Yagnesh Nagarajan, R. J. Hampton-Smith, 2019, PloS one.

Hormonally regulated follicle differentiation and luteinization in the mouse is associated with hypoxia inducible factor activity

Daniel J. Peet, Karen L. Kind, C. Bracken, 2010, Molecular and Cellular Endocrinology.

Power to see—Drivers of aerobic glycolysis in the mammalian retina: A review

D. Peet, Cameron D. Haydinger, T. Kittipassorn, 2020, Clinical & experimental ophthalmology.

Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation.

D. Peet, M. Whitelaw, D. Lando, 2003, European journal of biochemistry.

Cell-specific Regulation of Hypoxia-inducible Factor (HIF)-1α and HIF-2α Stabilization and Transactivation in a Graded Oxygen Environment*

Daniel J. Peet, C. Bracken, D. Peet, 2006, Journal of Biological Chemistry.

Hypoxic Induction of the Regulator of G-Protein Signalling 4 Gene Is Mediated by the Hypoxia-Inducible Factor Pathway

S. Olechnowicz, D. Peet, A. Fedele, 2012, PloS one.

Additional file 7

Debra L. Fulton, Wyeth W. Wasserman, Philip Bradley, 2012 .

Reciprocal regulation of the basic helix–loop–helix/Per–Arnt–Sim partner proteins, Arnt and Arnt2, during neuronal differentiation

D. Peet, Nan Hao, M. Whitelaw, 2013, Nucleic acids research.

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

A. von Kriegsheim, R. Wenger, D. Peet, 2016, PLoS biology.

Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH)

Melinda M. Mulvihill, E. Komives, D. Peet, 2010, FEBS letters.

Substrate Requirements of the Oxygen-sensing Asparaginyl Hydroxylase Factor-inhibiting Hypoxia-inducible Factor*

G. Booker, D. Peet, M. Whitelaw, 2004, Journal of Biological Chemistry.

Accelerated loss of hypoxia response in zebrafish with familial Alzheimer’s disease-like mutation of Presenilin 1

G. Halliday, D. Peet, S. Jayadev, 2019, bioRxiv.

Accelerated loss of hypoxia response in zebrafish with familial Alzheimer's disease-like mutation of Presenilin 1.

G. Halliday, D. Peet, S. Jayadev, 2020, Human molecular genetics.

Accelerated loss of hypoxia response in zebrafish with familial Alzheimer’s disease-like mutation of Presenilin 1

G. Halliday, D. Peet, S. Jayadev, 2019, bioRxiv.

The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses

C. Bracken, D. Peet, M. Whitelaw, 2003, Cellular and Molecular Life Sciences CMLS.

Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders

J. Rosenfeld, D. Peet, M. Whitelaw, 2021, Scientific Reports.

The LXRs: a new class of oxysterol receptors.

D. Peet, D. Mangelsdorf, B. A. Janowski, 1998, Current opinion in genetics & development.

Cancer‐like metabolism of the mammalian retina

D. Peet, R. Casson, G. Chidlow, 2015, Clinical & experimental ophthalmology.

M-Type Pyruvate Kinase Isoforms and Lactate Dehydrogenase A in the Mammalian Retina: Metabolic Implications.

D. Peet, R. Casson, G. Chidlow, 2016, Investigative ophthalmology & visual science.

A comparative study of covalently-bound fatty acids in keratinized tissues.

D. Peet, R. Wettenhall, D. Rivett, 1992, Comparative biochemistry and physiology. B, Comparative biochemistry.

Hairs from patients with maple syrup urine disease show a structural defect in the fiber cuticle.

D. Peet, D. Danks, A. Negri, 1996, The Journal of investigative dermatology.

The Chemistry of the Cuticle Surface of Keratin Fibers

D. Peet, D. Rivett, R.E.H. Wettenhall, 1995 .

Factor Inhibiting HIF (FIH) Recognizes Distinct Molecular Features within Hypoxia-inducible Factor-α (HIF-α) versus Ankyrin Repeat Substrates*

D. Peet, A. Chapman-Smith, Sarah E Wilkins, 2012, The Journal of Biological Chemistry.

Turn me on: regulating HIF transcriptional activity

D. Peet, K. Lisy, 2008, Cell Death and Differentiation.

The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia

D. Peet, R. Johnson, A. Cowburn, 2018, Cell metabolism.

Characterization of the novel spontaneously immortalized rat Müller cell line SIRMu‐1

D. Peet, R. Casson, J. Wood, 2019, Experimental eye research.

HIF signalling: The eyes have it.

D. Peet, R. Casson, G. Chidlow, 2017, Experimental cell research.

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.

M. Dyer, S. O’Rahilly, N. Wareham, 2009, The Journal of clinical investigation.

MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors

D. Peet, M. Whitelaw, Adrienne E. Sullivan, 2016, The FEBS journal.

Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator.

C. Bracken, D. Peet, M. Whitelaw, 2005, Journal of Biological Chemistry.

Cancer‐like metabolism of the mammalian retina

D. Peet, R. Casson, G. Chidlow, 2015, Clinical & experimental ophthalmology.

Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).

D. Peet, Johana Chicher, J. Gorman, 2009, The international journal of biochemistry & cell biology.

Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH)

Melinda M. Mulvihill, E. Komives, D. Peet, 2010, FEBS letters.

Covalently Bound Fatty Acids and Ceramides in Wool

D. Peet, H. Cornell, A. Negri, 1996 .

Hypoxia inducible factor single nucleotide polymorphisms: exploring the role of HIF polymorphisms in retinal disease

D. Peet, Thaksaon Kittipassorn, 2015, Clinical & experimental ophthalmology.