B. Blom

发表

Human arm weight compensation in rehabilitation robotics: efficacy of three distinct methods

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2020, Journal of NeuroEngineering and Rehabilitation.

Additional file 3

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2012 .

The Transcription Factor Encyclopedia

Debra L. Fulton, Henriette O'Geen, Elodie Portales-Casamar, 2012, Genome Biology.

STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression

B. Blom, H. Spits, F. Scheeren, 2005, Nature Immunology.

Interleukin-12 and -23 Control Plasticity of CD127(+) Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria.

C. Buskens, W. Bemelman, B. Blom, 2015, Immunity.

DAP12-deficient mice fail to develop autoimmunity due to impaired antigen priming.

B. Blom, L. Lanier, A. Cerwenka, 2000, Immunity.

Developmental origin of pre-DC2.

B. Blom, H. Spits, R. Schotte, 2002, Human immunology.

The Plasmacytoid Dendritic Cell as the Swiss Army Knife of the Immune System: Molecular Regulation of Its Multifaceted Functions

J. Karrich, B. Blom, L. Jachimowski, 2014, The Journal of Immunology.

Modulation of Signal Strength Switches Notch from an Inducer of T Cells to an Inducer of ILC2

B. Blom, H. Spits, C. Helbig, 2013, Front. Immunol..

IL-23 as a Cancer Vaccine Adjuvant Immunological and Antitumor Effects of

Anna M. Keller, B. Blom, R. Kastelein, 2013 .

Immunological and Antitumor Effects of IL-23 as a Cancer Vaccine Adjuvant1

Anna M. Keller, B. Blom, R. Kastelein, 2006, The Journal of Immunology.

Synergy between IL-15 and Id2 Promotes the Expansion of Human NK Progenitor Cells, Which Can Be Counteracted by the E Protein HEB Required To Drive T Cell Development

B. Blom, A. Bakker, H. Spits, 2010, The Journal of Immunology.

TCR gene rearrangements and expression of the pre-T cell receptor complex during human T-cell differentiation.

J. V. van Dongen, B. Blom, M. Heemskerk, 1999, Blood.

IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis.

K. Karube, R. Bende, L. Smit, 2008, Blood.

Mesenchymal Stromal Cells Stimulate the Proliferation and IL-22 Production of Group 3 Innate Lymphoid Cells

B. Blom, C. Voermans, J. Bernink, 2018, The Journal of Immunology.

Innate Lymphoid Cells Proliferation and IL-22 Production of Group Mesenchymal Stromal Cells Stimulate the Hazenberg

Jochem, B. Blom, C. Voermans, 2018 .

Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates

Åsa K. Björklund, B. Blom, H. Spits, 2017, Cell reports.

Early Effects of HTLV-1 Infection on the Activation, Exhaustion, and Differentiation of T-Cells in Humanized NSG Mice

B. Berkhout, B. Blom, J. Villaudy, 2021, Cells.

that activated STAT5 is required for Hodgkin lymphomagenesis IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence

K. Karube, L. Smit, K. Ohshima, 2008 .

Cloning and expression of murine CD27: comparison with 4‐1BB, another lymphocyte‐specific member of the nerve growth factor receptor family

B. Blom, W. Loenen, E. de Vries, 1993, European journal of immunology.

Peripheral T Cell Homeostasis Mice without Affecting - / - c g IL-2R - / - Rag2 Development in ''Human Immune System'' IL-7 Enhances Thymic Human T Cell

B. Blom, A. Bakker, H. Spits, 2009 .

IL-7 Enhances Thymic Human T Cell Development in “Human Immune System” Rag2−/−IL-2Rγc−/− Mice without Affecting Peripheral T Cell Homeostasis1

B. Blom, J. D. Di Santo, A. Bakker, 2009, The Journal of Immunology.

Pim1 Reconstitutes Thymus Cellularity in Interleukin 7–And Common γ Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not Cd3γ-Deficient Mice

B. Blom, A. Berns, H. Spits, 1999, The Journal of experimental medicine.

Downregulation of CD1 Marks Acquisition of Functional Maturation of Human Thymocytes and Defines a Control Point in Late Stages of Human T Cell Development

B. Blom, H. Spits, T. Hori, 1997, The Journal of experimental medicine.

IFN-α Is Constitutively Expressed in the Human Thymus, but Not in Peripheral Lymphoid Organs

B. Blom, L. Jachimowski, C. Uittenbogaart, 2011, PloS one.

PIM1 Reconstitutes Thymus Cellularity in Interleukin 7– and Common (cid:103) Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not CD3 (cid:103) -deﬁcient Mice

B. Blom, A. Berns, H. Spits, 1999 .

The Transcription Factor Encyclopedia The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2012 .

Disruption of αβ but not of γδ T cell development by overexpression of the helix–loop–helix protein Id3 in committed T cell progenitors

J. V. van Dongen, B. Blom, M. Heemskerk, 1999 .

Isolation and in vitro generation of gene-manipulated human plasmacytoid and conventional dendritic cells.

J. Karrich, B. Blom, H. Spits, 2010, Methods in molecular biology.

Required To Drive T Cell Development Which Can Be Counteracted by the E Protein Expansion of Human NK Progenitor Cells , Synergy between IL-15 and Id 2 Promotes the Yasuda

B. Blom, A. Bakker, H. Spits, 2010 .

IL-6 triggers IL-21 production by human CD4+ T cells to drive STAT3-dependent plasma cell differentiation in B cells

B. Blom, H. Spits, S. Diehl, 2012, Immunology and cell biology.

A doxycycline-dependent human immunodeficiency virus type 1 replicates in vivo without inducing CD4+ T-cell depletion.

A. Das, B. Berkhout, B. Blom, 2012, The Journal of general virology.

CD31, a Valuable Marker to Identify Early and Late Stages of T Cell Differentiation in the Human Thymus

B. Blom, B. Jamieson, M. Nagasawa, 2017, The Journal of Immunology.

TCR Gene Rearrangements and Expression of the Pre-T Cell Receptor Complex During Human T-Cell Differentiation

B. Blom, M. Heemskerk, J. Dongen, 1999 .

The Role of the Common Gamma Chain of the IL-2, IL-4, IL-7 and IL-15 Receptors in Development of Lymphocytes. Constitutive Expression of Bcl-2 does not Rescue the Developmental Defects in Gamma Common-Deficient Mice

B. Blom, H. Spits, P. Krimpenfort, 1997 .

Profiling the fungal microbiome after FMT for graft-versus-host disease: insights from a phase 1 interventional study.

T. Rolling, T. Hohl, B. Blom, 2022, Transplantation and cellular therapy.

Fetal liver contains committed NK progenitors, but is not a site for development of CD34+ cells into T cells.

B. Blom, L. Lanier, J. Phillips, 1997, Journal of immunology.

seven IFN-α REGULATES T CELL DIFFERENTIATION IN THE HUMAN THYMUS BY SETTING THE THRESHOLD FOR THYMIC EGRESS

B. Blom, L. Jachimowski, C. Uittenbogaart, 2015 .

PJA-BP expression and TCR delta deletion during human T cell differentiation.

J. V. van Dongen, B. Blom, A. Bogers, 1998, International immunology.

PJA-BP expression and TCR δ deletion during human T cell differentiation

B. Blom, A. Bogers, J. Dongen, 1998 .

Cell-fate decisions in early T cell development: regulation by cytokine receptors and the pre-TCR.

B. Blom, H. Spits, M. Oosterwegel, 1999, Seminars in immunology.

Thymic stromal lymphopoietin induces early human B‐cell proliferation and differentiation

B. Blom, H. Spits, F. Scheeren, 2010, European journal of immunology.

Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix‐loop‐helix factor E2‐2 and the Ets factor Spi‐B

B. Blom, M. Hazekamp, R. Schotte, 2008, European journal of immunology.

Endogenous IFN-alpha production by plasmacytoid dendritic cells exerts an antiviral effect on thymic HIV-1 infection.

B. Blom, H. Spits, C. Uittenbogaart, 2004, Journal of immunology.

Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease.

B. Blom, H. Spits, M. V. van Oers, 2014, Blood.

susceptibility to graft-versus-host disease Activated innate lymphoid cells are associated with a reduced

B. Blom, H. Spits, J. Mjösberg, 2014 .

Early stages in the development of human T, natural killer and thymic dendritic cells

B. Blom, M. Heemskerk, J. Dongen, 1998, Immunological reviews.

Prethymic CD34+ progenitors capable of developing into T cells are not committed to the T cell lineage.

B. Blom, H. Spits, P. Res, 1997, Journal of immunology.

and Spi-B dendritic cell versus T-cell lineage decision through control of GATA-3 Delta-like1-induced Notch1 signaling regulates the human plasmacytoid

B. Blom, H. Spits, F. Scheeren, 2012 .

Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B.

B. Blom, H. Spits, F. Scheeren, 2006, Blood.

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

J Wagner, B. Blom, R. Kastelein, 2000, Immunity.

Down-regulation of the macrophage lineage through interaction with OX2 (CD200).

B. Blom, W. Streit, A. Barclay, 2000, Science.

Human CD5+ Innate Lymphoid Cells Are Functionally Immature and Their Development from CD34+ Progenitor Cells Is Regulated by Id2

B. Blom, H. Spits, M. Nagasawa, 2017, Front. Immunol..

Single-Cell Transcriptomics Reveals Discrete Steps in Regulatory T Cell Development in the Human Thymus

B. Blom, R. V. van Lier, A. Mahfouz, 2021, The Journal of Immunology.

GATA2 haploinsufficient patients lack innate lymphoid cells that arise after hematopoietic cell transplantation

B. Blom, H. Spits, L. Krabbendam, 2022, Frontiers in Immunology.

Introduction: TH2-inducing DC2 for immunotherapy.

B. Blom, Y. Liu, Yong‐jun Liu, 2000, Blood.

cell precursors in vivo Intrathymic and extrathymic development of human plasmacytoid dendritic

B. Blom, J. Seppen, H. Spits, 2013 .

Factors Contributing to HIV-1 Induced Pathogenesis in the Human Thymus

B. Blom, C. Uittenbogaart, M. Epeldegui, 2011 .

Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo.

B. Blom, J. Seppen, H. Spits, 2002, Blood.

Generation of Interferon α–Producing Predendritic Cell (Pre-Dc)2 from Human Cd34+ Hematopoietic Stem Cells

B. Blom, S. Ho, S. Antonenko, 2000, The Journal of experimental medicine.

Pathogens Use and Abuse MicroRNAs to Deceive the Immune System

B. Blom, Thomas B Flór, 2016, International journal of molecular sciences.

Allogeneic hematopoietic cell transplantation, the microbiome, and graft-versus-host disease

B. Blom, M. Hazenberg, Y. V. van Lier, 2023, Gut microbes.

The ETS Transcription Factor Spi-B Is Required for Human Plasmacytoid Dendritic Cell Development

B. Blom, H. Spits, R. Schotte, 2004, The Journal of experimental medicine.

New Insights in the Development of Human B Lymphocytes

B. Blom, 2012 .

Development of human lymphoid cells.

B. Blom, H. Spits, 2006, Annual review of immunology.

Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

G. Nolan, B. Blom, A. Bakker, 1997, The Journal of experimental medicine.

Innate lymphoid cells in treatment-induced gastrointestinal pathogenesis.

B. Blom, M. Hazenberg, Said Z. Omar, 2020, Current opinion in supportive and palliative care.

The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells.

Hergen Spits, Wytske J Fokkens, W. Fokkens, 2012, Immunity.

Human ectoenzyme-expressing ILC3: immunosuppressive innate cells that are depleted in graft-versus-host disease.

C. Buskens, W. Bemelman, B. Blom, 2019, Blood advances.

ILCs in hematologic malignancies: Tumor cell killers and tissue healers.

B. Blom, M. Hazenberg, V. van Hoeven, 2019, Seminars in immunology.

Human thymus regeneration and T cell reconstitution.

B. Blom, H. Spits, W. Dontje, 2007, Seminars in immunology.

Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells.

B. Blom, H. Spits, E. Wijnands, 2004, Blood.

Presence of Innate Lymphoid Cells in Allogeneic Hematopoietic Grafts Correlates with Reduced Graft-Versus-Host Disease

B. Blom, S. Gassen, C. Voermans, 2022, Transplantation and Cellular Therapy.

From interleukin‐23 to T‐helper 17 cells: human T‐helper cell differentiation revisited

B. Blom, R. de Waal Malefyt, K. Boniface, 2008, Immunological reviews.

Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2-/-γc-/-) mouse model

B. Berkhout, B. Blom, H. Spits, 2009, Gene Therapy.

Donor fecal microbiota transplantation ameliorates intestinal graft-versus-host disease in allogeneic hematopoietic cell transplant recipients

B. Blom, M. Nieuwdorp, M. Hazenberg, 2020, Science Translational Medicine.

development Stimulated plasmacytoid dendritic cells impair human T-cell

B. Blom, H. Spits, M. Spaargaren, 2013 .

Stimulated plasmacytoid dendritic cells impair human T-cell development.

B. Blom, H. Spits, M. Spaargaren, 2006, Blood.

Development and activation of regulatory T cells in the human fetus

B. Blom, H. Spits, T. Cupedo, 2005, European journal of immunology.

In vivo modulation of gene expression by lentiviral transduction in "human immune system" Rag2-/- gamma c -/- mice.

J. Karrich, B. Blom, H. Spits, 2010, Methods in molecular biology.

Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors.

B. Blom, S. Antonenko, B. Blazar, 2004, Blood.

The transcriptional regulator NAB2 reveals a two‐step induction of TRAIL in activated plasmacytoid DCs

J. Karrich, B. Blom, J. Medema, 2012, European journal of immunology.

four IL-21 STIMULATED HUMAN PLASMACYTOID DENDRITIC CELLS SECRETE GRANZYME B , WHICH IMPAIRS THEIR CAPACITY TO INDUCE T CELL PROLIFERATION

J. Karrich, B. Blom, L. Jachimowski, 2015 .

IL-21-stimulated human plasmacytoid dendritic cells secrete granzyme B, which impairs their capacity to induce T-cell proliferation.

J. Karrich, B. Blom, L. Jachimowski, 2013, Blood.

New insights into the regulation of human B-cell differentiation.

B. Blom, S. Diehl, H. Schmidlin, 2009, Trends in immunology.

Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression.

Hergen Spits, B. Blom, H. Spits, 2008, Blood.

Endogenous IFN-α Production by Plasmacytoid Dendritic Cells Exerts an Antiviral Effect on Thymic HIV-1 Infection1

B. Blom, H. Spits, C. Uittenbogaart, 2004, The Journal of Immunology.

Additional file 7

Debra L. Fulton, Wyeth W. Wasserman, Philip Bradley, 2012 .

dendritic cell precursors from human hematopoietic progenitors

B. Blom, S. Antonenko, B. Blazar, 2013 .

T cell precursors in man and mice.

B. Blom, H. Spits, P. Res, 1998, Critical reviews in immunology.

GPA33: A Marker to Identify Stable Human Regulatory T Cells

A. Scott, B. Blom, J. Borst, 2020, The Journal of Immunology.

Alternative splicing and differential expression of the islet autoantigen IGRP between pancreas and thymus contributes to immunogenicity of pancreatic islets but not diabetogenicity in humans

B. Blom, M. Engelse, F. Staal, 2013, Diabetologia.

Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human T cells from the thymus to the periphery.

B. Blom, L. Jachimowski, C. Uittenbogaart, 2016, The Journal of allergy and clinical immunology.

EXPRESSION OF THE C-TYPE LECTIN BDCA-2 ON PLASMACYTOID DENDRITIC CELLS IS DIRECTLY REGULATED BY THE TRANSCRIPTION FACTOR SPI-B

J. Karrich, B. Blom, Roos-Marijn Berbers, 2015 .

MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells.

J. Karrich, B. Blom, A. Iyer, 2013, Blood.

The transcription factor Spi-B regulates human plasmacytoid dendritic cell survival through direct induction of the antiapoptotic gene BCL2-A1.

J. Karrich, B. Blom, S. Kamihira, 2012, Blood.

and XBP-1 expression Spi-B inhibits human plasma cell differentiation by repressing BLIMP1

B. Blom, H. Spits, F. Scheeren, 2013 .

Notch Ligands Expressed by Follicular Dendritic Cells Protect Germinal Center B Cells from Apoptosis

B. Blom, Y. Choi, Xin Zhang, 2009, The Journal of Immunology.

Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation.

M. Goumans, B. Blom, I. Costa, 2021, Cell stem cell.

Autoregulatory lentiviral vectors allow multiple cycles of doxycycline-inducible gene expression in human hematopoietic cells in vivo

B. Berkhout, B. Blom, J. Seppen, 2010, Gene Therapy.

Hergen Spits—A legend at the top of his career

B. Blom, J. Mjösberg, Maria Grazia Roncarolo, 2021, Allergy.

Cells from Apoptosis Dendritic Cells Protect Germinal Center B Notch Ligands Expressed by Follicular

B. Blom, Y. Choi, Xin Zhang, 2009 .

BST2/Tetherin is constitutively expressed on human thymocytes with the phenotype and function of Treg cells

B. Blom, C. Uittenbogaart, M. Epeldegui, 2015, European journal of immunology.

six THE PLASMACYTOID DENDRITIC CELL SPECIFIC C-TYPE LECTIN BDCA-2 BINDS A NATURAL LIGAND ON HUMAN THYMOCYTES

B. Blom, Roos-Marijn Berbers, L. Jachimowski, 2015 .

Antiviral Effect on Thymic HIV-1 Infection Plasmacytoid Dendritic Cells Exerts an Production by a Endogenous IFN-Hergen

B. Blom, C. Uittenbogaart, Kevin B. Gurney, 2004 .

Use of a Novel Chimeric Mouse Model with a Functionally Active Human Immune System To Study Human Immunodeficiency Virus Type 1 Infection

B. Blom, H. Spits, I. Chen, 2007, Clinical and Vaccine Immunology.

transcriPtion factor sPi-b and nf-κb subunits regulates Plasmacytoid dendritic cell activation and survival

J. Karrich, B. Blom, M. Nagasawa, 2013 .

Drug exporter expression correlates with group 3 innate lymphoid cell resistance to immunosuppressive agents

B. Blom, M. Hazenberg, V. van Hoeven, 2023, Frontiers in Hematology.

Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors.

J. V. van Dongen, B. Blom, H. Spits, 1999, The EMBO journal.

IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis.

K. Karube, R. Bende, L. Smit, 2008, Blood.

Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease.

B. Blom, H. Spits, J. Mjösberg, 2014, Blood.

Synergy between IL-15 and Id2 Promotes the Expansion of Human NK Progenitor Cells, Which Can Be Counteracted by the E Protein HEB Required To Drive T Cell Development

B. Blom, A. Bakker, H. Spits, 2010, The Journal of Immunology.

IL-21-stimulated human plasmacytoid dendritic cells secrete granzyme B, which impairs their capacity to induce T-cell proliferation.

J. Karrich, B. Blom, L. Jachimowski, 2013, Blood.

Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression.

B. Blom, H. Spits, F. Scheeren, 2008, Blood.

The transcription factor Spi-B regulates human plasmacytoid dendritic cell survival through direct induction of the antiapoptotic gene BCL2-A1.

J. Karrich, B. Blom, S. Kamihira, 2012, Blood.

Preclinical In Vivo Evaluation of the Safety of a Multi-shRNA-based Gene Therapy Against HIV-1

B. Berkhout, B. Blom, C. Voermans, 2013, Molecular therapy. Nucleic acids.

Presence of innate lymphoid cells in allogeneic hematopoietic grafts correlates with reduced graft-versus-host disease.

B. Blom, C. Voermans, M. Hazenberg, 2022, Cytotherapy.