C. Mattos

发表

All-atom empirical potential for molecular modeling and dynamics studies of proteins.

Alexander D. MacKerell, M. Karplus, D. Nguyen, 1998, The journal of physical chemistry. B.

Locating and characterizing binding sites on proteins

D. Ringe, C. Mattos, 1996, Nature Biotechnology.

Shift in the equilibrium between on and off states of the allosteric switch in Ras-GppNHp affected by small molecules and bulk solvent composition.

C. Mattos, G. Holzapfel, G. Buhrman, 2012, Biochemistry.

Multiple solvent crystal structures of ribonuclease A: An assessment of the method

Carla Mattos, C. Mattos, M. Dechene, 2009, Proteins.

Protein-water interactions in a dynamic world.

Carla Mattos, C. Mattos, 2002, Trends in biochemical sciences.

Multiple solvent crystal structures: probing binding sites, plasticity and hydration.

G. Petsko, D. Vitkup, D. Ringe, 2006, Journal of molecular biology.

Proteins in organic solvents.

D. Ringe, C. Mattos, Carla Mattos, 2001, Current opinion in structural biology.

Allosteric effects of the oncogenic RasQ61L mutant on Raf-RBD.

R. Nussinov, B. Ma, C. Mattos, 2015, Structure.

Allosteric modulation of Ras positions Q61 for a direct role in catalysis

C. Mattos, G. Holzapfel, G. Buhrman, 2010, Proceedings of the National Academy of Sciences.

An Experimental Approach to Mapping the Binding Surfaces of Crystalline Proteins

Karen N. Allen, G. Petsko, D. Ringe, 1996 .

Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP γ-Phosphate*

Carla Mattos, Flora Meilleur, Ryan Knihtila, 2015, The Journal of Biological Chemistry.

The Ras–Membrane Interface: Isoform-Specific Differences in the Catalytic Domain

C. Mattos, J. Parker, 2015, Molecular Cancer Research.

Direct Attack on RAS: Intramolecular Communication and Mutation-Specific Effects

Kendra Marcus, Carla Mattos, C. Mattos, 2015, Clinical Cancer Research.

DRoP: a water analysis program identifies Ras-GTP-specific pathway of communication between membrane-interacting regions and the active site.

C. Mattos, P. Swartz, B. Kearney, 2014, Journal of molecular biology.

Analogous inhibitors of elastase do not always bind analogously

Dagmar Ringe, Carla Mattos, Gregory A. Petsko, 1994, Nature Structural Biology.

Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor.

C. Mattos, K. Verba, Mychal Smith, 2020, Acta crystallographica. Section D, Structural biology.

'Pathway drug cocktail': targeting Ras signaling based on structural pathways.

Ruth Nussinov, Chung-Jung Tsai, Carla Mattos, 2013, Trends in molecular medicine.

Neutron scattering in the biological sciences: progress and prospects.

Christopher B. Stanley, Jeremy C. Smith, M. Weinrich, 2018, Acta crystallographica. Section D, Structural biology.

Allosteric modulation of caspase 3 through mutagenesis

C. Mattos, P. Swartz, A. C. Clark, 2012, Bioscience reports.

Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors.

G A Petsko, G. Petsko, D. Ringe, 1995, Biochemistry.

Minimizing frustration by folding in an aqueous environment.

C. Mattos, A. C. Clark, A. Clark, 2008, Archives of biochemistry and biophysics.

Predicting X‐ray solution scattering from flexible macromolecules

C. Mattos, L. Makowski, H. Guterres, 2018, Protein science : a publication of the Protein Society.

Titration of ionizable groups in proteins using multiple neutron data sets from a single crystal: application to the small GTPase Ras.

C. Mattos, F. Meilleur, Ryan Knihtila, 2019, Acta crystallographica. Section F, Structural biology communications.

Raf promotes dimerization of the Ras G-domain with increased allosteric connections

J. Groves, C. Mattos, M. Buck, 2020, Proceedings of the National Academy of Sciences.

Expression, purification, crystallization and X-ray data collection for RAS and its mutants

C. Mattos, G. Buhrman, J. Colicelli, 2015, Data in brief.

Analysis of binding site hot spots on the surface of Ras GTPase.

Dima Kozakov, Sandor Vajda, Carla Mattos, 2011, Journal of molecular biology.

Rapid folding and unfolding of Apaf-1 CARD.

C. Mattos, N. Nicely, B. Feeney, 2007, Journal of molecular biology.

Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3.

C. Mattos, P. Swartz, C. Pop, 2006, Biochemistry.

Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.

C. Mattos, P. Swartz, A. C. Clark, 2011, Archives of biochemistry and biophysics.

X‐ray structural and simulation analysis of a protein mutant: The value of a combined approach

M. Karplus, B. Tidor, C. Mattos, 2004, Proteins.

Fragment-based identification of druggable 'hot spots' of proteins using Fourier domain correlation techniques

Dima Kozakov, Ryan Brenke, Dmitri Beglov, 2009, Bioinform..

A comprehensive survey of Ras mutations in cancer.

Carla Mattos, C. Mattos, I. Prior, 2012, Cancer research.

The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects

Carla Mattos, Petr Kuzmic, Ryan Knihtila, 2017, The Journal of Biological Chemistry.

Transformation efficiency of RasQ61 mutants linked to structural features of the switch regions in the presence of Raf.

Carla Mattos, C. Mattos, G. Buhrman, 2007, Structure.

The K-Ras, N-Ras, and H-Ras Isoforms: Unique Conformational Preferences and Implications for Targeting Oncogenic Mutants.

Carla Mattos, C. Mattos, Jillian A Parker, 2018, Cold Spring Harbor perspectives in medicine.

Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding

T. Graeber, C. Mattos, J. Colicelli, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase*

Murat Cirit, Jason M Haugh, Carla Mattos, 2010, The Journal of Biological Chemistry.

Organic solvents order the dynamic switch II in Ras crystals.

Carla Mattos, C. Mattos, G. Buhrman, 2003, Structure.

Regulation of GTPase function by autophosphorylation

M. Ikura, D. Morrison, J. Paulo, 2021, bioRxiv.

Crystal Structure Reveals the Full Ras–Raf Interface and Advances Mechanistic Understanding of Raf Activation

C. Mattos, T. Cookis, 2020, bioRxiv.

Raf promotes dimerization of the Ras G‐domain

J. Groves, C. Mattos, M. Buck, 2020, The FASEB Journal.

The allosteric switch and conformational states in Ras GTPase affected by small molecules.

Carla Mattos, C. Mattos, Christian W. Johnson, 2013, The Enzymes.

Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D

C. Mattos, A. Aguirre, K. Haigis, 2019, Cell reports.

Targeting Cancer from a Structural Biology Perspective

C. Mattos, Derion Reid, 2019, Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach.

Isoform-Specific Destabilization of the Active Site Reveals Molecular Mechanism of Intrinsic Activation of KRas G13D

C. Mattos, K. Haigis, J. Parker, 2019, SSRN Electronic Journal.

K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D.

Carla Mattos, C. Mattos, Jillian A Parker, 2018, Structure.

A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis

C. Mattos, G. Salvesen, P. Swartz, 2009, The Biochemical journal.

An engineered protein antagonist of K-Ras/B-Raf interaction

K Dane Wittrup, Carla Mattos, Ryan Knihtila, 2017, Scientific Reports.

Water in Ras Superfamily Evolution

Kendra Marcus, Carla Mattos, C. Mattos, 2020, J. Comput. Chem..

Computational studies of the principle of dynamic-change-driven protein interactions.

C. Mattos, M. Buck, Zhen-lu Li, 2022, Structure.

Crystal structures of Ral-GppNHp and Ral-GDP reveal two binding sites that are also present in Ras and Rap.

C. Mattos, N. Nicely, V. de Serrano, 2004, Structure.

Ras: structural details to guide direct targeting

C. Mattos, 2015, Aging.

Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond.

Carla Mattos, Jungsan Sohn, J. Rudolph, 2005, Biochemistry.

DRoP: Automated detection of conserved solvent‐binding sites on proteins

C. Mattos, M. Dechene, P. Swartz, 2019, Proteins.

Allosteric site variants affect GTP hydrolysis on RAS

C. Mattos, S. Fetics, Kathleen P. Davis, 2023, bioRxiv.

Analysis of two-residue turns in proteins.

M Karplus, G A Petsko, M. Karplus, 1994, Journal of molecular biology.

The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin.

R. Nussinov, C. Mattos, L. Makowski, 2019, Structure.

Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features.

C. Mattos, G. Buhrman, E. Maxwell, 2011, Biochemistry.

Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding

T. Graeber, C. Mattos, J. Colicelli, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Commentary: Biochemistry and molecular biology educators launch national network

Margaret Johnson, Ellis Bell, Harold B White, 2010, Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology.

Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features.

C. Mattos, G. Buhrman, Keith T. Gagnon, 2011, Biochemistry.