S. Iyer

发表

An Integrated Encyclopedia of DNA Elements in the Human Genome

Raymond K. Auerbach, William Stafford Noble, Stephen C. J. Parker, 2012, Nature.

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

William Stafford Noble, Melissa C. Greven, E. Birney, 2012, Genome research.

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

Martin J. Aryee, J. Joung, C. Lareau, 2019, Nature.

Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain

M. Rivera, Nicolò Riggi, I. Stamenkovic, 2017, Cell.

Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer

Martin J. Aryee, Luli S. Zou, Sarah E. Johnstone, 2020, Cell.

The deacylase SIRT5 supports melanoma viability by regulating chromatin dynamics

Erika L. Varner, M. Rivera, Ho-Joon Lee, 2020, bioRxiv.

A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing

Martin J. Aryee, Jonathan Y. Hsu, J. Joung, 2020, Nature Biotechnology.

OTX2 Activity at Distal Regulatory Elements Shapes the Chromatin Landscape of Group 3 Medulloblastoma.

Martin J. Aryee, J. Mesirov, P. Tamayo, 2017, Cancer discovery.

The Impact of Big Data on the Physician

Ron C. Li, Jonathan H. Chen, S. Iyer, 2018 .

EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma

Martin J. Aryee, M. Rivera, Nicolò Riggi, 2022, Nature Communications.

Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia

Vasco M. Barreto, S. Iyer, Alexandra Veloso, 2022, Leukemia.

LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma.

M. Rivera, M. Suvà, Nicolò Riggi, 2020, Cell reports.

CD4+ T helper 2 cells suppress breast cancer by inducing terminal differentiation

M. Rivera, S. Iyer, W. Haas, 2022, The Journal of experimental medicine.

The macrophage‐expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish

S. Iyer, D. Langenau, V. Wittamer, 2019, bioRxiv.

The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies

M. Rivera, Nicolò Riggi, P. Provero, 2020, Life Science Alliance.

Analysis of genomic data to derive biological conclusions on (1) transcriptional regulation in the human genome and (2) antibody resistance in hepatitis C virus

S. Iyer, Sowmya Iyer, 2015 .

High-Throughput Sequencing Analysis of Post-Liver Transplantation HCV E2 Glycoprotein Evolution in the Presence and Absence of Neutralizing Monoclonal Antibody

Z. Weng, B. Pierce, P. Zamore, 2014, PloS one.

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates

Nicole M. Gaudelli, Christopher J. Cheng, K. G. Rajeev, 2021, Nature.

Regions Bound by 119 Human Transcription Factors Sequence Features and Chromatin Structure around the Genomic Material Supplemental

William Stafford Noble, Nathan C. Sheffield, Eurie L. Hong, 2012 .

Combination therapies to inhibit LCK tyrosine kinase and mTOR signaling in T-cell Acute Lymphoblastic Leukemia.

S. Iyer, M. Kelliher, C. Heckman, 2022, Blood.

Factorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium

Jie Wang, Zhiping Weng, Ewan Birney, 2012, Nucleic Acids Res..

The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics.

Erika L. Varner, M. Rivera, Ho-Joon Lee, 2021, The Journal of clinical investigation.

A (fire)cloud-based DNA methylation data preprocessing and quality control platform

Andrew Dunford, Martin J. Aryee, Gad Getz, 2019, BMC Bioinformatics.

Augmenting and directing long-range CRISPR-mediated activation in human cells

Martin J. Aryee, Luli S. Zou, J. Joung, 2021, Nature Methods.

CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells

J. Keith Joung, Sowmya Iyer, Sara P. Garcia, 2020, Nature Biotechnology.

PRL3 enhances T cell acute lymphoblastic leukemia growth through suppressing T cell signaling pathways and apoptosis

F. Speleman, S. Iyer, W. Haas, 2020, Leukemia.

Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors

Jeffry D. Sander, J. Joung, M. Rivera, 2022, Cell genomics.

Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing

McKenzie L. Shaw, Martin J. Aryee, C. Ceol, 2017, The Journal of experimental medicine.

Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia

F. Speleman, R. Sadreyev, S. Iyer, 2018, Leukemia.

Single-cell imaging of T cell immunotherapy responses in vivo

S. Iyer, M. Cobbold, Alexandra Veloso, 2021, The Journal of experimental medicine.

Epigenome editing of microsatellite repeats defines tumor-specific enhancer functions and dependencies

M. Rivera, Nicolò Riggi, I. Stamenkovic, 2018, Genes & development.

Global-scale CRISPR gene editor specificity profiling by ONE-seq identifies population-specific, variant off-target effects

Martin J. Aryee, Matthew C. Canver, David R. Liu, 2021, bioRxiv.

LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability.

M. Rivera, Nicolò Riggi, P. Provero, 2020, Cell reports.

Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma.

M. van de Rijn, J. Khan, S. Iyer, 2018, Cell stem cell.

CRISPR DNA base editors with reduced RNA off-target and self-editing activities

Martin J. Aryee, Martin J Aryee, Caleb A Lareau, 2019, Nature Biotechnology.