J. Luban

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The yeast two-hybrid system for studying protein-protein interactions.

J. Luban, S. Goff, Stephen Goff, 1995, Current opinion in biotechnology.

TRIM 5 retroviral restriction activity correlates with the ability to 2 induce innate immune signaling 3 4 5

J. Luban, Josefina Lascanoa, Pradeep Uchilb, 2017 .

TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling

P. Uchil, J. Luban, W. Mothes, 2015, Journal of Virology.

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

Jeremy Luban, J. Luban, C. Aiken, 2013, Retrovirology.

SARS-CoV-2

J. Luban, 2020 .

Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1

J. Luban, L. Berthoux, D. Sayah, 2004, Nature.

TRIM5α selectively binds a restriction-sensitive retroviral capsid

J. Luban, S. Sebastian, Sarah Sebastian, 2005, Retrovirology.

TRIM22 Inhibits HIV-1 Transcription Independently of Its E3 Ubiquitin Ligase Activity, Tat, and NF-κB-Responsive Long Terminal Repeat Elements

P. Uchil, J. Luban, A. Kajaste-Rudnitski, 2011, Journal of Virology.

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

Jeremy Luban, Caterina Strambio-De-Castillia, Walther Mothes, 2011, Nature.

HIV-1 unmasks the plasticity of innate lymphoid cells

T. Greenough, J. Luban, Alper Kucukural, 2017, bioRxiv.

Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon.

N. Yosef, B. Tabak, Xiaopeng Zhu, 2018, Cell systems.

The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5α

J. Luban, B. Schuler, M. Grütter, 2017, Journal of Virology.

The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5α

J. Luban, B. Schuler, M. Grütter, 2017, Journal of Virology.

ATPγS Disrupts Human Immunodeficiency Virus Type 1 Virion Core Integrity

J. Luban, S. Höglund, Anders Höglund, 2005, Journal of Virology.

The role of lysine 186 in HIV-1 integrase multimerization.

J. Luban, L. Berthoux, M. Muesing, 2007, Virology.

Disruption of Human TRIM5α Antiviral Activity by Nonhuman Primate Orthologues

J. Luban, L. Berthoux, D. Sayah, 2005, Journal of Virology.

Lv1 Inhibition of Human Immunodeficiency Virus Type 1 Is Counteracted by Factors That Stimulate Synthesis or Nuclear Translocation of Viral cDNA

J. Luban, L. Berthoux, Elena Sokolskaja, 2004, Journal of Virology.

- 1001 End Sequence Analysis Toolkit ( ESAT ) expands the extractable information from single-cell RNA-seq data

Rita, Allon M. Klein, D. Harlan, 2019 .

End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data

Maxim N. Artyomov, Allon M. Klein, D. Harlan, 2016, Genome research.

TRIM Protein-Mediated Regulation of Inflammatory and Innate Immune Signaling and Its Association with Antiretroviral Activity

P. Uchil, J. Luban, W. Mothes, 2012, Journal of Virology.

The Use of Variable Q1 Isolation Windows Improves Selectivity in LC-SWATH-MS Acquisition.

Ying Zhang, Frédérique Lisacek, Jeremy Luban, 2015, Journal of proteome research.

Vif Counteracts a Cyclophilin A-Imposed Inhibition of Simian Immunodeficiency Viruses in Human Cells

J. Luban, M. Khan, Thomas Pertel, 2007, Journal of Virology.

ActivityIts Association with Antiretroviral Inflammatory and Innate Immune Signaling TRIM Protein-Mediated Regulation of

P. Uchil, J. Luban, Thomas Pertel, 2013 .

Covalent Modification of Human Immunodeficiency Virus Type 1 p6 by SUMO-1

J. Luban, L. Berthoux, C. Gurer, 2005, Journal of Virology.

Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia

Changlian Zhu, K. Blomgren, P. Eriksson, 2007, The Journal of experimental medicine.

Translation Elongation Factor 1-Alpha Interacts Specifically with the Human Immunodeficiency Virus Type 1 Gag Polyprotein

J. Luban, A. Cimarelli, 1999, Journal of Virology.

Specific Incorporation of Heat Shock Protein 70 Family Members into Primate Lentiviral Virions

J. Luban, A. Cimarelli, C. Gurer, 2002, Journal of Virology.

Context-Dependent Phenotype of a Human Immunodeficiency Virus Type 1 Nucleocapsid Mutation

J. Luban, A. Cimarelli, 2001, Journal of Virology.

Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B

J. Luban, F Re, D Braaten, 1995, Journal of virology.

Primate immunodeficiency virus Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex

J. Luban, Kyusik Q Kim, Leonid A Yurkovetskiy, 2018, bioRxiv.

Primate immunodeficiency virus Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex

J. Luban, Kyusik Q Kim, Leonid A Yurkovetskiy, 2018, bioRxiv.

Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration

J. Luban, Baek Kim, Christian Reinhard, 2014, Retrovirology.

Isolation, characterization and targeted disruption of mouse ppia: cyclophilin A is not essential for mammalian cell viability.

J. Luban, J. Colgan, M. Asmal, 2000, Genomics.

Optimization by infusion of multiple reaction monitoring transitions for sensitive quantification of peptides by liquid chromatography/mass spectrometry.

T. Stricker, F. Lisacek, J. Luban, 2017, Rapid communications in mass spectrometry : RCM.

Single Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis [preprint]

Lawrence M. Lifshitz, Jiandie D. Lin, Jingyi, 2020 .

Single Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis

Lawrence M. Lifshitz, Jiandie D. Lin, J. Luban, 2020, bioRxiv.

Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis

Lawrence M. Lifshitz, Jiandie D. Lin, J. Luban, 2020, Cell reports.

Ranking Fragment Ions Based on Outlier Detection for Improved Label-Free Quantification in Data-Independent Acquisition LC-MS/MS.

Frédérique Lisacek, Jeremy Luban, Caterina Strambio-De-Castillia, 2015, Journal of proteome research.

Diabetes by Inhibition of the Receptor for Blockade of Late Stages of Autoimmune

J. Luban, K. Herold, J. Colgan, 2004 .

Blockade of Late Stages of Autoimmune Diabetes by Inhibition of the Receptor for Advanced Glycation End Products1

J. Luban, K. Herold, J. Colgan, 2004, The Journal of Immunology.

TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs.

B. Bisikirska, J. Bluestone, J. Luban, 2005, The Journal of clinical investigation.

HIV-1 and Ebola virus: The getaway driver nabbed

J. Luban, 2001, Nature Medicine.

Human Anti–HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1

J. Luban, L. Cavacini, D. Greiner, 2018, The Journal of Immunology.

Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication

R. Steinman, J. Luban, W. C. Voorhis, 1983, The Journal of experimental medicine.

Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity

J. Luban, S. Goff, I. Lowy, 1995, Journal of virology.

Cyclosporine A-Sensitive, Cyclophilin B-Dependent Endoplasmic Reticulum-Associated Degradation

J. Luban, Riccardo Bernasconi, M. Molinari, 2010, PloS one.

Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework

Lily A. Chylek, Belinda B. Flynn, Katherine C DeRuff, 2022, Med.

More than one way to TRIM a capsid

J. Luban, 2012, Proceedings of the National Academy of Sciences.

Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon

J. Luban, Thomas Pertel, Christian Reinhard, 2011, Retrovirology.

Selection for Loss of Ref1 Activity in Human Cells Releases Human Immunodeficiency Virus Type 1 from Cyclophilin A Dependence during Infection

J. Luban, D. Sayah, 2004, Journal of Virology.

Vaccine breakthrough infection leads to distinct profiles of neutralizing antibody responses by SARS-CoV-2 variant

J. Luban, M. Siedner, M. Goldberg, 2022, JCI Insight.

HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded

J. Luban, Shixia Wang, Shan Lu, 2017, Journal of Virology.

Cyclophilin binding to the human immunodeficiency virus type 1 Gag polyprotein is mimicked by an anti-cyclosporine antibody

J. Luban, B. Erlanger, E. K. Franke, 1995, Journal of virology.

ATPgammaS disrupts human immunodeficiency virus type 1 virion core integrity.

J. Luban, S. Höglund, Anders Höglund, 2005, Journal of virology.

Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness

Pardis C Sabeti, S. Schaffner, Nikolaos Barkas, 2022, Science.

Optimization of Nuclear Localization Signal Composition Improves CRISPR-Cas12a Editing Rates in Human Primary Cells.

J. Luban, L. Zhu, S. Wolfe, 2022, GEN biotechnology.

TRIM5α and TRIM22 Are Differentially Regulated According to HIV-1 Infection Phase and Compartment

M. Altfeld, T. Ndung’u, J. Luban, 2014, Journal of Virology.

Cyclophilin A and TRIM5 (cid:2) Independently Regulate Human Immunodeﬁciency Virus Type 1 Infectivity in Human Cells

J. Luban, L. Berthoux, Elena Sokolskaja, 2006 .

The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein

J. Luban, D. Braaten, H. Ansari, 1997, Journal of virology.

TRIM22 Inhibits HIV-1 Transcription Independently of Its E3-Ubiquitin Ligase 1

J. Luban, A. Kajaste-Rudnitski, W. Mothes, 2011 .

Specific binding of human immunodeficiency virus type 1 gag polyprotein and nucleocapsid protein to viral RNAs detected by RNA mobility shift assays

J. Luban, S. Goff, R. Berkowitz, 1993, Journal of virology.

Global profiling of human blood ILC subtypes reveals that NK cells produce homeostatic cytokine amphiregulin and sheds light on HIV-1 pathogenesis

Lawrence M. Lifshitz, J. Luban, S. Wolfe, 2022, bioRxiv.

Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein

J. Luban, S. Goff, W. Haseltine, 1993, Journal of virology.

p62/Sequestosome-1 Associates with and Sustains the Expression of Retroviral Restriction Factor TRIM5α

J. Luban, E. Campbell, Thomas Pertel, 2010, Journal of Virology.

Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1

R. Glockshuber, A. Heck, J. Luban, 2009, Proceedings of the National Academy of Sciences.

The retroviral restriction factor TRIM5α

J. Luban, Sarah Sebastian, 2007 .

Human cellular restriction factors that target HIV-1 replication

K. Jeang, J. Luban, K. Strebel, 2009, BMC medicine.

The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines

S. Peltz, J. Luban, C. Strambio-De-Castillia, 2020, Virus Research.

The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines

S. Peltz, J. Luban, C. Strambio-De-Castillia, 2020, bioRxiv.

Cyclophilin B Interacts with Sodium-Potassium ATPase and Is Required for Pump Activity in Proximal Tubule Cells of the Kidney

J. Luban, A. Meseguer, Thomas Pertel, 2010, PloS one.

Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

R. Bartenschlager, J. Luban, V. Lohmann, 2009, PLoS pathogens.

Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant

Pardis C Sabeti, S. Schaffner, J. Luban, 2020, Cell.

Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant

Pardis C Sabeti, S. Schaffner, J. Luban, 2020, bioRxiv.

Overcoming current limitations in humanized mouse research.

Jeremy Luban, J. Luban, D. Greiner, 2013, The Journal of infectious diseases.

Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.

Melis N. Anahtar, Katherine C DeRuff, Pardis C Sabeti, 2020, medRxiv.

Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages

R. Steinman, J. Luban, Z. Cohn, 1983, The Journal of experimental medicine.

Cyclophilin A, TRIM5, and Resistance to Human Immunodeficiency Virus Type 1 Infection

J. Luban, 2006, Journal of Virology.

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

Jeremy Luban, J. Luban, S. Goff, 1993, Cell.

Specific incorporation of cyclophilin A into HIV-1 virions

J. Luban, H. Yuan, E. K. Franke, 1994, Nature.

Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk.

A. Andreotti, J. Luban, J. Colgan, 2004, Immunity.

Cyclophilin A Peptidyl-Prolyl Isomerase Activity Promotes Zpr1 Nuclear Export

J. Luban, G. Greco, H. Ansari, 2002, Molecular and Cellular Biology.

Absconding with the Chaperone: Essential Cyclophilin–Gag Interaction in HIV-1 Virions

J. Luban, 1996, Cell.

Cyclophilin and gag in HIV-1 replication and pathogenesis.

J. Luban, E. K. Franke, 1995, Advances in experimental medicine and biology.

Cyclophilin A-Deficient Mice Are Resistant to Immunosuppression by Cyclosporine1

J. Luban, J. Colgan, M. Asmal, 2005, The Journal of Immunology.

HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency

Jeremy Luban, J. Luban, F. Santoni, 2012, Retrovirology.

Translation Elongation Factor 1-Alpha Interacts Specifically with the Human Immunodeficiency Virus Type 1 Gag Polyprotein

J. Luban, A. Cimarelli, 1999, Journal of Virology.

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

Sushovan Guha, Jeremy Luban, Paul A. Khavari, 1994, Cell.

AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma

A. Khvorova, J. Luban, K. Fitzgerald, 2021, The Journal of experimental medicine.

Deciphering the Code for Retroviral Integration Target Site Selection

Federico Andrea Santoni, Oliver Hartley, Jeremy Luban, 2010, PLoS Comput. Biol..

Production of ribosome components in effector CD4+ T cells is accelerated by TCR stimulation and coordinated by ERK-MAPK.

M. Magnasco, F. Naef, J. Luban, 2003, Immunity.

Optimization of NLS Composition Improves CRISPR-Cas12a Editing Rates in Human Primary Cells

J. Luban, L. Zhu, S. Wolfe, 2022, bioRxiv.

Enhanced Cas12a editing in mammalian cells and zebrafish

Lihua Julie Zhu, Jeremy Luban, Masahiro Shin, 2019, Nucleic acids research.

Optimization of human dendritic cell sample preparation for mass spectrometry-based proteomic studies.

F. Lisacek, Ying Zhang, J. Luban, 2015, Analytical biochemistry.

Innate immune sensing of HIV-1 by dendritic cells.

J. Luban, 2012, Cell host & microbe.

The piRNA Response to Retroviral Invasion of the Koala Genome

Z. Weng, J. Luban, W. Theurkauf, 2019, Cell.

Clarification of human blood ILC subtype interrelatedness and discovery of amphiregulin production by human NK cells shed light on HIV-1 pathogenesis

Lawrence M. Lifshitz, J. Luban, S. Wolfe, 2021, SSRN Electronic Journal.

Cyclophilin A and TRIM5α Independently Regulate Human Immunodeficiency Virus Type 1 Infectivity in Human Cells

J. Luban, L. Berthoux, Elena Sokolskaja, 2006, Journal of Virology.

Target Cell Cyclophilin A Modulates Human Immunodeficiency Virus Type 1 Infectivity

Jeremy Luban, J. Luban, D. Sayah, 2004, Journal of Virology.

Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription

J. Luban, D. Braaten, E. K. Franke, 1996, Journal of virology.

G2 cell cycle arrest and cyclophilin A in lentiviral gene transfer.

K. Cornetta, J. Luban, L. Sastry, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Mutational analysis of cis-acting packaging signals in human immunodeficiency virus type 1 RNA

J. Luban, S. Goff, 1994, Journal of virology.

Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein

J. Luban, S. Goff, 1991, Journal of virology.

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

S. Antonarakis, J. Luban, V. Sanctis, 2015, Nature.

Rescue of Multiple Viral Functions by a Second-Site Suppressor of a Human Immunodeficiency Virus Type 1 Nucleocapsid Mutation

J. Luban, S. Höglund, A. Cimarelli, 2000, Journal of Virology.

The Carboxyl-Terminus of Human Immunodeficiency Virus Type 2 Circulating Recombinant form 01_AB Capsid Protein Affects Sensitivity to Human TRIM5α

J. Luban, W. Sugiura, T. Miyamoto, 2012, PloS one.

Human Immunodeficiency Virus Type 1 Gag Polyprotein Multimerization Requires the Nucleocapsid Domain and RNA and Is Promoted by the Capsid-Dimer Interface and the Basic Region of Matrix Protein

J. Luban, J. Colgan, A. Cimarelli, 1999, Journal of Virology.

Specificity and sequence requirements for interactions between various retroviral Gag proteins

J. Luban, S. Goff, H. Yuan, 1994, Journal of virology.

Envelope-Dependent, Cyclophilin-Independent Effects of Glycosaminoglycans on Human Immunodeficiency Virus Type 1 Attachment and Infection

P. Bieniasz, J. Luban, S. Goff, 2002, Journal of Virology.

Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41

R. J. Lai, J. Luban, J. Heeney, 2011, PLoS pathogens.

Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA

J. Luban, A. De Iaco, 2014, Retrovirology.

Lentiviral Vector Gene Transfer Is Limited by the Proteasome at Postentry Steps in Various Types of Stem Cells

P. Cascio, M. Neri, J. Luban, 2008, Stem cells.

Cyclophilin A is required for TRIM5α-mediated resistance to HIV-1 in Old World monkey cells

J. Luban, L. Berthoux, Elena Sokolskaja, 2005 .

Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells.

J. Luban, L. Berthoux, Elena Sokolskaja, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors

P. Bieniasz, J. Luban, S. Goff, 2003, Nature Medicine.

Basic Residues in Human Immunodeficiency Virus Type 1 Nucleocapsid Promote Virion Assembly via Interaction with RNA

J. Luban, S. Höglund, A. Cimarelli, 2000, Journal of Virology.

Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein

J. Luban, S. Goff, W. Haseltine, 1993, Journal of virology.

Genetic assay for multimerization of retroviral gag polyproteins

J. Luban, S. Goff, K. Ålin, 1992, Journal of virology.

Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity

J. Luban, M. Pizzato, W. Diehl, 2019, bioRxiv.

Cyclophilin A regulates HIV‐1 infectivity, as demonstrated by gene targeting in human T cells

J. Luban, D. Braaten, 2001, The EMBO journal.

Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA

J. Luban, H. Bartels, 2014, Retrovirology.

A structural role for the PHP domain in E. coli DNA polymerase III A structural role for the PHP domain in E. coli DNA polymerase III Let us know how access to this document benefits you.

J. Luban, H. Bartels, 2019 .

The Retroviral Restriction Factor TRIM5 (cid:66)

J. Luban, Sarah Sebastian, 2007 .

Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization

J. Luban, J. Colgan, Han Yuan, 1996, Journal of virology.

Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration

J. Luban, L. Berthoux, Thomas Pertel, 2015, PLoS pathogens.

Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events

Melis N. Anahtar, Katherine C DeRuff, Pardis C Sabeti, 2020, Science.

Vaccine Breakthrough Infection with the SARS-CoV-2 Delta or Omicron (BA.1) Variant Leads to Distinct Profiles of Neutralizing Antibody Responses

Ashutosh Kumar Singh, J. Luban, M. Siedner, 2022, medRxiv.

As2O3 Enhances Retroviral Reverse Transcription and Counteracts Ref1 Antiviral Activity

P. Pandolfi, J. Luban, P. Salomoni, 2003, Journal of Virology.

TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

J. Luban, S. Sawyer, Kyusik Q Kim, 2019, bioRxiv.

Cyclophilin A protects HIV-1 from restriction by human TRIM5α

J. Luban, C. Strambio-De-Castillia, E. Campbell, 2019, Nature Microbiology.

2019-0611 TRIM 5 alpha Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

Fadila, J. Luban, S. Sawyer, 2019 .

The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Speciﬁc Binding Interface for TRIM5 (cid:2)

J. Luban, B. Schuler, Maximilian Mittelviefhaus, 2018 .

Closing the net on retroviruses

J. Luban, 2016, eLife.

HIV-1 capsid is involved in post-nuclear entry steps

G. Nicastro, I. Taylor, J. Luban, 2016, Retrovirology.

Cyclophilin A and HIV-1 Replication

J. Luban, 2014 .

The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating.

J. Luban, F. Diaz-Griffero, Yang Yang, 2014, Methods in molecular biology.

TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm

S. Antonarakis, J. Luban, F. Santoni, 2013, Retrovirology.

TRIM5 and the Regulation of HIV-1 Infectivity

J. Luban, 2012, Molecular biology international.

TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling.

J. Luban, M. Grütter, 2012, Current opinion in virology.

TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions

J. Luban, E. Campbell, Jaya Sastri, 2011, Retrovirology.

Association of TRIM22 with the Type 1 Interferon Response and Viral Control during Primary HIV-1 Infection

A. Brass, B. Walker, T. Ndung’u, 2010, Journal of Virology.

Association of TRIM 22 with the Type 1 Interferon Response and Viral Control during Primary HIV-1 Infection

A. Brass, B. Walker, J. Luban, 2010 .

Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components.

Jeremy Luban, Caterina Strambio-De-Castillia, L. Mazzucchelli, 2009, The Journal of clinical investigation.

Cyclophilin, TRIM5, and innate immunity to HIV-1.

J. Luban, Elena Sokolskaja, 2006, Current opinion in microbiology.

Arsenic Counteracts Human Immunodeficiency Virus Type 1 Restriction by Various TRIM5 Orthologues in a Cell Type-Dependent Manner

J. Luban, Elena Sokolskaja, Sarah Sebastian, 2006, Journal of Virology.

Disruption of Human TRIM5 (cid:2) Antiviral Activity by Nonhuman Primate Orthologues

J. Luban, L. Berthoux, D. Sayah, 2005 .

Cyclophilin A is required for the replication of group M human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus SIV(CPZ)GAB but not group O HIV-1 or other primate immunodeficiency viruses

J. Luban, D. Braaten, E. K. Franke, 1996, Journal of virology.

Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013–2016 Epidemic

Pardis C. Sabeti, Jeremy Luban, Andrew Rambaut, 2016, Cell.

The 2022 RSV surge was driven by multiple viral lineages

Pardis C Sabeti, S. Schaffner, J. Luban, 2023, medRxiv.

Lessons from a local effort to screen for SARS-CoV-2

J. Luban, N. J. Silverstein, Noah J. Silverstein, 2021, Proceedings of the National Academy of Sciences.

Innate lymphoid cells and disease tolerance in SARS-CoV-2 infection

B. Walker, Xu G. Yu, J. Luban, 2021, medRxiv.

Characterization of Simian Immunodeficiency Virus SIVSM/Human Immunodeficiency Virus Type 2 Vpx Function in Human Myeloid Cells

J. Luban, J. Darlix, C. Goujon, 2008, Journal of Virology.

Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness

Pardis C Sabeti, S. Schaffner, J. Luban, 2021, medRxiv.

Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111

Pardis C Sabeti, S. Schaffner, J. Kuhn, 2018, Viruses.

An emergent Ebola virus nucleoprotein variant influences virion budding, oligomerization, transcription and replication

Pardis C Sabeti, S. Schaffner, J. Kuhn, 2018, bioRxiv.

HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes.

J. Luban, S. Sazer, F. Chang, 2004, Molecular biology of the cell.

Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics

James B. Munro, K. Chandran, J. Luban, 2020, Viruses.

HIV-1 Vpr: G2 cell cycle arrest, macrophages and nuclear transport.

J. Luban, F. Re, 1997, Progress in cell cycle research.

TRIM34 acts with TRIM5 to restrict HIV and SIV capsids

M. Emerman, J. Luban, E. Campbell, 2019, bioRxiv.

HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells

Lawrence M. Lifshitz, T. Greenough, J. Brenchley, 2019, Nature Immunology.

End Sequence Analysis ToolKit ( ESAT ) expands the extractable from single cell RNA-seq experiments

Maxim N. Artyomov, Allon M. Klein, D. Harlan, 2016 .

HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation

J. Luban, Martin Lehmann, V. Piguet, 2009, PLoS pathogens.

TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner

M. Emerman, J. Luban, E. Campbell, 2020, PLoS pathogens.

Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike

James B. Munro, J. Luban, Yang Wang, 2021, bioRxiv.

HIV-1-induced cytokines deplete homeostatic ILCs and expand TCF7-dependent memory NK cells

Lawrence M. Lifshitz, T. Greenough, J. Luban, 2019 .

Constrained mutational sampling of amino acids in HIV-1 protease evolution

C. Schiffer, D. Bolon, T. Whitfield, 2018, bioRxiv.

Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines

J. Luban, A. Nowosielska, Kyusik Q Kim, 2017, Nature Communications.

Cyclophilin A Interacts with HIV-1 Vpr and Is Required for Its Functional Expression*

Jeremy Luban, Evelyn Schubert, Uwe Tessmer, 2003, Journal of Biological Chemistry.

The hidden cost of genetic resistance to HIV-1

J. Luban, 2019, Nature Network Boston.

HIV-1 capsid is involved in post-nuclear entry steps

I. Taylor, G. Nicastro, J. Luban, 2016, Retrovirology.

Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus

J. Luban, A. De Iaco, 2011, Retrovirology.

The HIV-1 capsid core is an opportunistic nuclear import receptor

S. Sarafianos, J. Luban, V. KewalRamani, 2021, bioRxiv.

Cyclosporine Blocks Incorporation of HIV-1 Envelope Glycoprotein into Virions

Jeremy Luban, Caterina Strambio-De-Castillia, J. Luban, 2010, Journal of Virology.

Cyclosporine blocks incorporation of HIV-1

J. Luban, S. Olivari, Elena Sokolskaja, 2010 .

Human Immunodeficiency Virus Type 1 Replication Is Modulated by Host Cyclophilin A Expression Levels

J. Luban, D. Braaten, Lei Yin, 1998, Journal of Virology.

Sequence Note: The HIV Type 1 Replication Block in Nonhuman Primates Is Not Explained by Differences in Cyclophilin A Primary Structure

J. Luban, J. Allan, L. Yin, 1998 .

Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A

J. Luban, W. Phares, D. Braaten, 1996, Journal of virology.

Effect of linker insertion mutations in the human immunodeficiency virus type 1 gag gene on activation of viral protease expressed in bacteria

J. Luban, S. Goff, C. Lee, 1993, Journal of Virology.

AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis

G. Kroemer, J. Luban, J. Penninger, 2004, Oncogene.

Global mRNA and chromatin accessibility profiling elucidate how HIV-1 perturbs ILC and NK cell subsets

Lawrence M. Lifshitz, J. Luban, S. Wolfe, 2021 .

Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection

B. Walker, Xu G. Yu, M. Betts, 2022, eLife.

Human Immunodeficiency Virus Type 1 Virion Density Is Not Determined by Nucleocapsid Basic Residues

J. Luban, A. Cimarelli, 2000, Journal of Virology.

An Invariant Surface Patch on the TRIM5α PRYSPRY Domain Is Required for Retroviral Restriction but Dispensable for Capsid Binding

Jeremy Luban, J. Luban, M. Grütter, 2009, Journal of Virology.

Inhibition of HIV-1 replication by cyclosporine A or related compounds correlates with the ability to disrupt the Gag-cyclophilin A interaction.

J. Luban, E. K. Franke, 1996, Virology.

The retroviral restriction factor TRIM5alpha.

J. Luban, Sarah Sebastian, 2007, Current infectious disease reports.

Assignment of cyclophilin A (PPIA) to human chromosome band 7p13by in situ hybridization.

J. Luban, D. Warburton, D. Braaten, 1996, Cytogenetics and Cell Genetics.

Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues.

J. Luban, L. Berthoux, D. Sayah, 2005, Journal of virology.

HIV-1 Infection: Going Nuclear with TNPO3/Transportin-SR2 and Integrase

J. Luban, 2008, Current Biology.

Regulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome

James B. Munro, J. Luban, Ramesh Govindan, 2023, bioRxiv.

Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding

James B. Munro, K. Chandran, J. Luban, 2020, PLoS biology.

gag polyproteins. Genetic assay for multimerization of retroviral

J. Luban, S. Goff, K. Ålin, 2013 .

Genetic AssayforMultimerization ofRetroviral gag Polyproteins

J. Luban, K. L. Bossolt, T. Humaran, 1992 .

Targeting of the Tec kinase ITK drives resolution of T cell-mediated colitis and emerges as potential therapeutic option in ulcerative colitis.

M. Neurath, M. Vieth, J. Luban, 2021, Gastroenterology.

Processing strategies and software solutions for data‐independent acquisition in mass spectrometry

Markus Müller, Frédérique Lisacek, Jeremy Luban, 2015, Proteomics.

A Dual Task for the Xbp1-responsive OS-9 Variants in the Mammalian Endoplasmic Reticulum

J. Luban, Riccardo Bernasconi, M. Molinari, 2008, Journal of Biological Chemistry.

Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike

James B. Munro, J. Luban, Yang Wang, 2022, eLife.

Median bundle neurons coordinate behaviours during Drosophila male courtship

J. Luban, L. Berthoux, D. Sayah, 2017 .

Viral Lineages in the 2022 RSV Surge in the United States.

Katherine C DeRuff, S. Schaffner, J. Luban, 2023, The New England journal of medicine.

SARS-CoV-2 Reinfection in a Liver Transplant Recipient

J. Luban, P. Sabeti, D. Park, 2021, Annals of Internal Medicine.

Innate lymphoid cells and disease tolerance in SARS-CoV-2 infection [preprint]

J. Luban, Yetao Wang, Jonathan Z. Li, 2021 .

SARS-CoV-2 Spike protein variant D614G increases infectivity and retains sensitivity to antibodies that target the receptor binding domain

Pardis C Sabeti, S. Schaffner, J. Luban, 2020, bioRxiv.

S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness

James B. Munro, J. Luban, Xuping Xie, 2023, bioRxiv.

OMEGA: a software tool for the management, analysis, and dissemination of intracellular trafficking data that incorporates motion type classification and quality control

Ivo F. Sbalzarini, Tiziano Leidi, Jeremy Luban, 2018, bioRxiv.

Cytotoxic CD4 Development Requires CD4 Effectors to Concurrently Recognize Local Antigen and Encounter Infection-Induced IL-15

J. Luban, S. Swain, Allen M. Vong, 2022, bioRxiv.

SARS-CoV-2 Spike protein variant D614G increases infectivity and retains sensitivity to antibodies that target the receptor binding domain [preprint]

Pardis C Sabeti, S. Schaffner, J. Luban, 2020 .

Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV‐1 pathogenesis

Lawrence M. Lifshitz, J. Luban, S. Wolfe, 2023, The EMBO journal.

Reducing the inherent auto-inhibitory interaction within the pegRNA enhances prime editing efficiency

J. Luban, S. Wolfe, N. Lawson, 2023, Nucleic acids research.

Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination

James B. Munro, J. Luban, K. Shen, 2023, Nature communications.

Novel, accurate pathogen sensors for fast detection of SARS-CoV-2 in the aerosol in seconds for a breathalyzer platform

Sydney S. Cash, Ping Liu, U. Mitra, 2023, Biosensors and Bioelectronics: X.

Consulting the Oracle of SARS-CoV-2 Infection

J. Luban, J. Lemieux, 2021, The Journal of infectious diseases.

The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species- The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5alpha Specific Binding Interface for TRIM5alpha us you.

J. Luban, B. Schuler, Maximilian Mittelviefhaus, 2021 .

Cyclophilin A protects HIV-1 from restriction by human TRIM5α

J. Luban, E. Campbell, Kyusik Q Kim, 2019, Nature Microbiology.

TRIM 5 retroviral restriction activity correlates with the ability to 2 induce innate immune signaling 3 4 5

J. Luban, Josefina Lascanoa, Pradeep Uchilb, 2017 .

TRIM 5 retroviral restriction activity correlates with the ability to 2 induce innate immune signaling 3 4 5

J. Luban, Josefina Lascanoa, Pradeep Uchilb, 2015 .

Intron-containing RNA from the HIV-1 provirus activates type I Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines interferon and inflammatory cytokines us know how access to this document benefits you.

J. Luban, Kyusik Q Kim, Leonid A Yurkovetskiy, 2022 .

Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness

Pardis C Sabeti, S. Schaffner, Nikolaos Barkas, 2022, Science.

Overcoming current limitations in humanized mouse research.

J. Luban, D. Greiner, L. Shultz, 2013, The Journal of infectious diseases.

The Double-stranded RNA Binding Domain of the Vaccinia Virus E3L Protein Inhibits Both RNA- and DNA-induced Activation of Interferon β

J. Luban, D. Garcin, D. Kolakofsky, 2009, The Journal of Biological Chemistry.

Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus

J. Luban, C. Aiken, C. Dash, 2023, Journal of virology.