D. Bok

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A brief review of retinitis pigmentosa and the identified retinitis pigmentosa genes.

J. Phelan, D. Bok, James K. Phelan, 2000, Molecular vision.

The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited

Don H. Anderson, M. Hauser, D. Bok, 2010, Progress in retinal and eye research.

Bipolar assembly of caveolae in retinal pigment epithelium.

D. Bok, Jane G Hu, B. Shin, 2006, American journal of physiology. Cell physiology.

Degenerative changes in a retina affected with autosomal dominant retinitis pigmentosa.

J. Flannery, A. Bird, D. Bok, 1989, Investigative ophthalmology & visual science.

Localization of cellular retinol-binding protein and retinol-binding protein in cells comprising the blood-brain barrier of rat and human.

D. Bok, P. N. MacDonald, D. Ong, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Processing and transport of retinoids by the retinal pigment epithelium

D. Bok, 1990, Eye.

Ocular disease mechanisms elucidated by genetics of human fetal retinal pigment epithelium gene expression

Nathan S. Abell, Michael J. Gloudemans, B. Balliu, 2018, bioRxiv.

Membrane receptors for retinol-binding protein in cultured human retinal pigment epithelium.

J. Flannery, D. Bok, V. Clark, 1986, Investigative ophthalmology & visual science.

The renewal of diffusely distributed protein in the outer segments of rods and cones.

D. Bok, R. W. Young, Dean Bok, 1972, Vision research.

THE OSMOTIC BEHAVIOR OF ROD PHOTORECEPTOR OUTER SEGMENT DISCS

D. Bok, T. Ostwald, J. Heller, 1971, The Journal of cell biology.

Effect of illumination on the membrane permeability of rod photoreceptor discs.

D. Bok, T. Ostwald, J. Heller, 1970, Biochemistry.

Biosynthesis and assembly of the rod outer segment membrane system. Formation and fate of visual pigment in the frog retina.

D. Bok, M. Hall, A. D. Bacharach, 1969, Journal of Molecular Biology.

Effects of adeno-associated virus-vectored ciliary neurotrophic factor on retinal structure and function in mice with a P216L rds/peripherin mutation.

W. Hauswirth, M. Lavail, J. Duncan, 2002, Experimental eye research.

Proceedings: Autoradiographic and radiobiochemical studies on the incorporation of (6-3H)glucosamine into frog rhodopsin.

D. Bok, S. Basinger, M. Hall, 1974, Experimental eye research.

Visual Pigment Renewal in the Mature Frog Retina

D. Bok, M. Hall, A. D. Bacharach, 1968, Science.

Deficiency of rds/peripherin causes photoreceptor death in mouse models of digenic and dominant retinitis pigmentosa

R. Mcinnes, D. Bok, D. Birch, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Understanding RPE lipofuscin.

J. Dowling, D. Bok, J. Sparrow, 2013, Investigative ophthalmology & visual science.

mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice.

Xiyan Li, M. Lavail, D. Bok, 2011, The Journal of clinical investigation.

Transgenic Analysis of Rds/Peripherin N‐Glycosylation

D. Bok, G. Travis, W. Kedzierski, 1999, Journal of neurochemistry.

Dietary restriction retards age-related loss of gamma crystallins in the mouse lens.

R. Weindruch, D. Bok, R. Walford, 1984, Science.

Immunocytochemical localization of the lens main intrinsic polypeptide (MIP26) in communicating junctions

D. Bok, J. Horwitz, J. Dockstader, 1982, The Journal of cell biology.

A third form of the G protein beta subunit. 1. Immunochemical identification and localization to cone photoreceptors.

D. Bok, H. Yamane, B. K. Fung, 1992, The Journal of biological chemistry.

Low docosahexaenoic acid levels in rod outer segment membranes of mice with rds/peripherin and P216L peripherin mutations.

D. Bok, R. E. Anderson, M. Maude, 2001, Investigative ophthalmology & visual science.

Esterification of all-trans-retinol in normal human epithelial cell strains and carcinoma lines from oral cavity, skin and breast: reduced expression of lecithin:retinol acyltransferase in carcinoma lines.

D. Bok, L. Gudas, R. Rando, 2000, Carcinogenesis.

Cellular mechanisms of retinal degenerations: RPE65, ABCA4, RDS, and bicarbonate transporter genes as examples.

D. Bok, 2005, Retina.

Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration

S. Sarfare, D. Bok, M. Radeke, 2018, Proceedings of the National Academy of Sciences.

Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases.

D. Bok, K. Widder, R. Radu, 2005, Investigative ophthalmology & visual science.

Reduced Lecithin

S. Boorjian, S. Tickoo, D. Bok, 2004, Clinical Cancer Research.

Molecular Cloning and Characterization of the G Protein γ Subunit of Cone Photoreceptors (*)

D. Bok, H. Yamane, B. K. Fung, 1995, The Journal of Biological Chemistry.

Somatic ablation of the Lrat gene in the mouse retinal pigment epithelium drastically reduces its retinoid storage.

P. Chambon, D. Bok, N. Ghyselinck, 2007, Investigative ophthalmology & visual science.

Immunocytochemical localization of cellular retinol binding protein in the rat retina.

D. Bok, F. Chytil, D. Ong, 1984, Investigative ophthalmology & visual science.

The distribution and renewal of RNA in retinal rods.

D. Bok, 1970, Investigative ophthalmology.

The use of cultured human fetal retinal pigment epithelium in studies of the classical retinoid visual cycle and retinoid-based disease processes.

D. Bok, Jane G Hu, Jane Hu, 2014, Experimental eye research.

Time course of auditory impairment in mice lacking the electroneutral sodium bicarbonate cotransporter NBC3 (slc4a7).

A. Ishiyama, I. Lopez, D. Bok, 2005, Brain research. Developmental brain research.

Polarity of ll-cis Retinal Release from Cultured Retinal Pigment Epithelium

D. Bok, A. Carlson, 2005 .

Animal Model Inducible Expression of Vascular Endothelial Growth Factor in Adult Mice Causes Severe Proliferative Retinopathy and Retinal Detachment

P. Campochiaro, D. Zack, D. Bok, 2002 .

An autoradiographic analysis of postnatal cell proliferation in the normal and degenerative mouse retina

D. Bok, J. Blanks, J. C. Blanks, 1977, The Journal of comparative neurology.

Transplantation of retinal pigment epithelial cells and immune response in the subretinal space.

D. Bok, Xiaoyan Zhang, X. Zhang, 1998, Investigative ophthalmology & visual science.

Phagocytosis of outer segments by retinal pigment epithelium: phagosome-lysosome interaction.

D. Bok, J. Horwitz, E. Bosch, 1993, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged culture.

P. Bernstein, D. Bok, R. Hunt, 1995, Investigative ophthalmology & visual science.

Synthesis and secretion of retinol-binding protein and transthyretin by cultured retinal pigment epithelium.

D. Bok, James T. Davis, D. Ong, 1994, Biochemistry.

TIMP-3 is expressed in the human retinal pigment epithelium.

D. Bok, P. Brett, A. Ruiz, 1996, Biochemical and biophysical research communications.

Structural and functional characterization of recombinant human cellular retinaldehyde‐binding protein

D. Bok, J. Horwitz, L. Luck, 1998, Protein science : a publication of the Protein Society.

Lipoprotein (a) displays increased accumulation compared with low-density lipoprotein in the murine arterial wall.

D. Bok, A. Lusis, A. Scanu, 1994, Chemistry and physics of lipids.

Three homologs of rds/peripherin in Xenopus laevis photoreceptors that exhibit covalent and non-covalent interactions.

D. Bok, G. Travis, W. Moghrabi, 1996, Journal of cell science.

Immunoferritin localization of actin in retinal photoreceptors.

D. Bok, M. Chaitin, 1986, Investigative ophthalmology & visual science.

Generation and analysis of transgenic mice expressing P216L-substituted rds/peripherin in rod photoreceptors.

D. Bok, D. Birch, G. Travis, 1997, Investigative ophthalmology & visual science.

Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia.

D. Bok, Jane G Hu, E. Rodriguez-Boulan, 2005, Proceedings of the National Academy of Sciences of the United States of America.

25 - Transgenic Rescue of the Photoreceptor Dysplasia and Degeneration in Retinal Degeneration Slow (rds) Mutant Mice

D. Bok, G. Travis, 1993 .

A Molecular Characterization of the Retinal Degeneration Slow (rds) Mouse Mutation

D. Bok, G. Travis, 1993 .

Diacylglycerol O-Acyltransferase Type-1 Synthesizes Retinyl Esters in the Retina and Retinal Pigment Epithelium

D. Bok, Jane G Hu, J. Kaylor, 2015, PloS one.

Title Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epithelium

D. Bok, Jane G Hu, J. Kaylor, 2015 .

Retinoid X receptor beta (RXRB) expression in Sertoli cells controls cholesterol homeostasis and spermiation.

D. Bok, M. Mark, N. Ghyselinck, 2008, Reproduction.

cholesterol homeostasis and spermiation

D. Bok, M. Mark, N. Ghyselinck, 2008 .

RXR beta expression in Sertoli cells controls cholesterol homeostasis and spermiation

D. Bok, M. Mark, N. Ghyselinck, 2008 .

A specific receptor for retinol binding protein as detected by the binding of human and bovine retinol binding protein to pigment epithelial cells.

D. Bok, M. Heller, 1976, American journal of ophthalmology.

Pigment epithelium-photoreceptor interactions in the normal and dystrophic rat retina.

D. Bok, N. Custer, 1975, Experimental eye research.

A novel form of transducin-dependent retinal degeneration: accelerated retinal degeneration in the absence of rod transducin.

D. Bok, Zhongyan Wang, M. Obin, 2007, Investigative ophthalmology & visual science.

The basolateral targeting signal of CD147 (EMMPRIN) consists of a single leucine and is not recognized by retinal pigment epithelium.

D. Bok, Jane G Hu, G. Kreitzer, 2004, Molecular biology of the cell.

Uptake, processing and release of retinoids by cultured human retinal pigment epithelium.

J. Flannery, D. Bok, J. Horwitz, 1990, Experimental eye research.

Retinal Pigment Epithelium-Retinal G Protein Receptor-Opsin Mediates Light-dependent Translocation of All-trans-retinyl Esters for Synthesis of Visual Chromophore in Retinal Pigment Epithelial Cells*

D. Bok, Jane G Hu, R. Radu, 2008, Journal of Biological Chemistry.

Peropsin modulates transit of vitamin A from retina to retinal pigment epithelium

J. Nathans, D. Bok, R. Radu, 2017, The Journal of Biological Chemistry.

Title Peropsin modulates transit of vitamin A from retina to retinal pigment epithelium Permalink

J. Nathans, D. Bok, R. Radu, 2017 .

Glycosaminoglycan synthesis and secretion by the retinal pigment epithelium: polarized delivery of hyaluronan from the apical surface.

D. Bok, J. Hollyfield, A. Calabro, 2001, Journal of cell science.

Glutathione transport in human retinal pigment epithelial (HRPE) cells: apical localization of sodium-dependent gsh transport.

D. Bok, R. Kannan, D. Tang, 2001, Experimental eye research.

Immunolocalization of electrogenic sodium-bicarbonate cotransporters pNBC1 and kNBC1 in the rat eye.

D. Bok, I. Kurtz, A. Pushkin, 2001, American journal of physiology. Renal physiology.

Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas

D. Bok, J. ten Hoeve, K. Reue, 2022, bioRxiv.

Why the macula?

A. Bird, D. Bok, 2017, Eye.

Transport of retinol from the blood to the retina: an autoradiographic study of the pigment epithelial cell surface receptor for plasma retinol-binding protein.

D. Bok, J. Heller, 1976, Experimental eye research.

Genomic organization and mutation analysis of the gene encoding lecithin retinol acyltransferase in human retinal pigment epithelium.

E. Stone, D. Bok, G. Hageman, 2001, Investigative ophthalmology & visual science.

Lecithin retinol acyltransferase contains cysteine residues essential for catalysis.

D. Bok, R. Rando, A. Ruiz, 2000, Biochemistry.

Differential expression and function of ABCG1 and ABCG4 during development and aging.

Greg D. Gale, Paul T. Tarr, Desmond J. Smith, 2010, Journal of lipid research.

Claudin localization in cilia of the retinal pigment epithelium

D. Bok, H. Sakaguchi, Jane G Hu, 2002, The Anatomical record.

Function of MYO7A in the human RPE and the validity of shaker1 mice as a model for Usher syndrome 1B.

David S. Williams, D. Bok, Jane G Hu, 2010, Investigative ophthalmology & visual science.

Immunocytochemical localization of the main intrinsic polypeptide (MIP) in ultrathin frozen sections of rat lens

D. Bok, J. Horwitz, P. Fitzgerald, 1983, The Journal of cell biology.

Transport of retinol from the blood to the retina: involvement of high molecular weight lipoproteins as intracellular carriers.

D. Bok, J. Heller, 1976, Experimental eye research.

Ciliary neurotrophic factor therapy for inherited retinal diseases: pros and cons.

D. Bok, 2005, Retina.

The role of RPE65 in inherited retinal diseases.

D. Bok, 2005, Retina.

Immunocytochemical localization of the main intrinsic polypeptide (MIP) in ultrathin frozen sections of rat lens

D. Bok, P. Fitzgerald, Joseph HORWlTZ, 1983, The Journal of cell biology.

Focus on molecules: lecithin retinol acyltransferase.

D. Bok, A. Ruiz, 2010, Experimental eye research.

Reduced Lecithin:Retinol Acyltransferase Expression Correlates with Increased Pathologic Tumor Stage in Bladder Cancer

S. Boorjian, S. Tickoo, D. Bok, 2004 .

Detection of interphotoreceptor retinoid binding protein (IRBP) mRNA in human and cone-dominant squirrel retinas by in situ hybridization.

D. Bok, S. Bhat, K. Porrello, 1991, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Rescue of enzymatic function for disease-associated RPE65s containing various missense mutations in non-active sites*

D. Bok, T. Izumi, Songhua Li, 2014 .

Practical Remarks on Gout, Rheumatic Fever, and Chonic Rheumatism of the Joints; Being the Substance of the Croonian Lectures for the Present Year, Delivered at the College of Physicians

D. Bok, R. W. Young, Robert Bentley Todd, 1844, Edinburgh Medical and Surgical Journal.

Conformational properties of the main intrinsic polypeptide (MIP26) isolated from lens plasma membranes.

D. Bok, J. Horwitz, 1987, Biochemistry.

Blindness and auditory impairment caused by loss of the sodium bicarbonate cotransporter NBC3

A. Ishiyama, I. Lopez, D. Bok, 2003, Nature Genetics.

Hydroxyindole‐O‐Methyltransferase in Y‐79 Human Retinoblastoma Cells: Effect of Cell Attachment

D. Bok, G. Chader, A. Kyritsis, 1987, Journal of neurochemistry.

Molecular and cellular alterations induced by sustained expression of ciliary neurotrophic factor in a mouse model of retinitis pigmentosa.

W. Hauswirth, M. Lavail, J. Duncan, 2007, Investigative ophthalmology & visual science.

Peroxidase diffusion in the normal and laser-coagulated primate retina.

D. Bok, G. Peyman, 1972, Investigative ophthalmology.

Characterization of the 3' UTR sequence encoded by the AQP-1 gene in human retinal pigment epithelium.

D. Bok, A. Ruiz, 1996, Biochimica et biophysica acta.

Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement.

D. Bok, G. Jaffe, W. Stamer, 2003, Investigative ophthalmology & visual science.

A cell culture medium that supports the differentiation of human retinal pigment epithelium into functionally polarized monolayers.

D. Bok, D Bok, J Hu, 2001, Molecular vision.

Retinol metabolism and lecithin:retinol acyltransferase levels are reduced in cultured human prostate cancer cells and tissue specimens.

Dean Bok, David M Nanus, Beatrice S Knudsen, 2002, Cancer research.

THE ROLE OF THE PIGMENT EPITHELIUM IN THE ETIOLOGY OF INHERITED RETINAL DYSTROPHY IN THE RAT

D. Bok, M. Hall, 1971, The Journal of cell biology.

Autoradiographic studies on the metabolism of the retinal pigment epithelium.

D. Bok, R. W. Young, Dean Bok, 1970, Investigative ophthalmology.

Retinal photoreceptor-pigment epithelium interactions. Friedenwald lecture.

D. Bok, 1985, Investigative ophthalmology & visual science.

Localization of hydroxyindole-O-methyltransferase in the mammalian pineal gland and retina.

D. Bok, J. Horwitz, A. F. Wiechmann, 1985, Investigative ophthalmology & visual science.

Melatonin-binding in the frog retina: autoradiographic and biochemical analysis.

D. Bok, J. Horwitz, A. F. Wiechmann, 1986, Investigative ophthalmology & visual science.

Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity

D. Bok, J. Tombran-Tink, L. Johnson, 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Chloride transport in cultured fetal human retinal pigment epithelium.

D. Frambach, D. Bok, J G Hu, 1996, Experimental eye research.

Localization of NaK ATPase on cultured human retinal pigment epithelium.

D. Frambach, D. Bok, R. Gallemore, 1994, Investigative ophthalmology & visual science.

The retinal pigment epithelium: a versatile partner in vision

D. Bok, D Bok, 1993, Journal of Cell Science.

Promotion of the release of 11-cis-retinal from cultured retinal pigment epithelium by interphotoreceptor retinoid-binding protein.

D. Bok, A. Carlson, 1992, Biochemistry.

A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A

P. Ping, D. Bok, R. Kawaguchi, 2007, Science.

Borane dimethylamine reduction of the retinal--opsin linkage in rhodopsin.

D. Bok, M. Hall, 1982, Methods in enzymology.

Reduction of the retinal-opsin linkage in isolated frog retinas.

D. Bok, M. Hall, 1976, Experimental eye research.

Na,K-ATPase inhibition alters tight junction structure and permeability in human retinal pigment epithelial cells.

Dean Bok, D. Bok, A. Rajasekaran, 2003, American journal of physiology. Cell physiology.

Autoradiographic and biochemical analysis of photoreceptor membrane renewal inOctopus retina

D. Bok, L. J. Robles, Castor S. Cabebe, 1984, Journal of neurocytology.

Rhodopsin chromophore exchanges among opsin molecules in the dark.

D. Bok, D. Defoe, 1983, Investigative ophthalmology & visual science.

Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation.

D. Bok, Q. Yuan, R. Radu, 2008, Investigative ophthalmology & visual science.

Studies on the Assembly of Rod Outer Segment Disc Membranes

D. Bok, S. Basinger, M. Hall, 1973 .

Rhodopsin in the rod outer segment plasma membrane

D. Bok, S. Basinger, M. Hall, 1976, The Journal of cell biology.

Incorporation of (3H)vitamin A into rhodopsin in light- and dark-adapted frogs.

D. Bok, M. Hall, 1974, Experimental eye research.

Immunocytochemical localization of photopigments in cephalopod retinae

D. Bok, D. Bok, A. Watanabe, 1987, Journal of neurocytology.

Joram Heller 1934–1980

D. Bok, J. Horwitz, B. Straatsma, 1980, Vision Research.

Retinal Photorecepfor-Pigment Epithelium Interactions Friedenwold Lecture

D. Bok, 2005 .

The retinal degeneration slow (rds) gene product is a photoreceptor disc membrane-associated glycoprotein

J. Sutcliffe, D. Bok, G. Travis, 1991, Neuron.

GABA‐ergic pathways in the goldfish retina

W. Stell, R. Marc, D. Bok, 1978, The Journal of comparative neurology.

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle

D. Bok, D. Hamasaki, Jian-xing Ma, 1998, Nature Genetics.

Blood vascular abnormalities in the degenerative mouse retina (C57BL/6J-rd le).

D. Bok, M. Matthes, 1984, Investigative ophthalmology & visual science.

Properties of channels reconstituted from the major intrinsic protein of lens fiber membranes

G. Zampighi, D. Bok, J. Horwitz, 1990, The Journal of general physiology.

The Energy Expenditure of Tinikling : A Culturally Relevant Filipino Dance

A. Angosta, D. Bok, D. Heil, 2018 .

Molecular and Biochemical Characterization of Lecithin Retinol Acyltransferase*

D. Bok, R. Rando, Y. Lim, 1999, The Journal of Biological Chemistry.

Expression and synthesis of the Na,K-ATPase beta 2 subunit in human retinal pigment epithelium.

D. Bok, S. Bhat, A. Ruiz, 1996, Gene.

Analysis and Quantitation of mRNAs Encoding the α- and β-Subunits of Rod Photoreceptor cGMP Phosphodiesterase in Neonatal Retinal Degeneration ( rd ) Mouse Retinas

J. Phelan, D. Bok, 2000 .

Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells.

Tamar Dvash, David S. Williams, D. Bok, 2010, Human molecular genetics.

Characterization and quantification of full-length and truncated Na, K-ATPase α1 and β1 RNA transcripts expressed in human retinal pigment epithelium

D. Bok, S. Bhat, A. Ruiz, 1995 .

Polarized budding of vesicular stomatitis and influenza virus from cultured human and bovine retinal pigment epithelium.

D. Bok, E. Rodriguez-Boulan, W. O'day, 1992, Experimental eye research.

Genetic analyses of human fetal retinal pigment epithelium gene expression suggest ocular disease mechanisms

Nathan S. Abell, Michael J. Gloudemans, B. Balliu, 2019, Communications Biology.

Evidence for an inflammatory process in age-related macular degeneration gains new support.

D. Bok, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Regulatory mechanism for the transmembrane receptor that mediates bidirectional vitamin A transport

D. Bok, F. Mancia, R. Kawaguchi, 2020, Proceedings of the National Academy of Sciences.

Secretory Defect and Cytotoxicity

D. Bok, W. Gordon, A. Haas, 2013, The Journal of Biological Chemistry.

Secretory Defect and Cytotoxicity THEPOTENTIALDISEASEMECHANISMSFORTHERETINITISPIGMENTOSA (RP)-ASSOCIATEDINTERPHOTORECEPTORRETINOID-BINDINGPROTEIN(IRBP) *

D. Bok, W. Gordon, A. Haas, 2013 .

The Role of Interphotoreceptor Retinoid-Binding Protein on the Translocation of Visual Retinoids and Function of Cone Photoreceptors

D. Bok, R. Radu, G. Travis, 2009, The Journal of Neuroscience.

Purification and characterization of a transmembrane domain-deleted form of lecithin retinol acyltransferase.

D. Bok, L. Xue, R. Rando, 2003, Biochemistry.

Restoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degeneration

D. Bok, M. Radeke, L. V. Johnson, 2015, Genome Medicine.

Evidence of complement dysregulation in outer retina of Stargardt disease donor eyes

D. Bok, J. Hollyfield, V. Bonilha, 2020, Redox biology.

Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease

Dean Bok, Zhichun Jiang, S. Sarfare, 2017, Proceedings of the National Academy of Sciences.

Bisretinoid-mediated Complement Activation on Retinal Pigment Epithelial Cells Is Dependent on Complement Factor H Haplotype*

D. Bok, R. Radu, Zhichun I. Jiang, 2014, The Journal of Biological Chemistry.

Complement System Dysregulation and Inflammation in the Retinal Pigment Epithelium of a Mouse Model for Stargardt Macular Degeneration*

D. Bok, R. Radu, G. Travis, 2011, The Journal of Biological Chemistry.

Culture of highly differentiated human retinal pigment epithelium for analysis of the polarized uptake, processing, and secretion of retinoids.

D. Bok, Jane Hu, 2010, Methods in molecular biology.

Contributions of genetics to our understanding of inherited monogenic retinal diseases and age-related macular degeneration.

D. Bok, 2007, Archives of ophthalmology.

Photoreceptor “Retinoid Pumps” in Health and Disease

D. Bok, 1999, Neuron.

Temperature-sensitive retinoid isomerase activity of RPE65 mutants associated with Leber Congenital Amaurosis.

S. Jacobson, D. Bok, A. Aiyar, 2015, Journal of biochemistry.

Rescue of Enzymatic Function for Disease-associated RPE65 Proteins Containing Various Missense Mutations in Non-active Sites*

S. Jacobson, D. Bok, T. Izumi, 2014, The Journal of Biological Chemistry.

Non-Cell-Autonomous Photoreceptor Degeneration in rdsMutant Mice Mosaic for Expression of a Rescue Transgene

D. Bok, G. Travis, W. Kedzierski, 1998, The Journal of Neuroscience.

Is the Duchenne muscular dystrophy gene also an X-linked retinitis pigmentosa locus?

J. Phelan, D. Bok, 2000, Molecular genetics and metabolism.

Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas

D. Bok, J. ten Hoeve, K. Reue, 2021, bioRxiv.

Tetracycline-inducible system for photoreceptor-specific gene expression.

D. Zack, R. DePinho, B. Conklin, 2000, Investigative ophthalmology & visual science.

Retinoid content, visual responses, and ocular morphology are compromised in the retinas of mice lacking the retinol-binding protein receptor, STRA6.

D. Bok, M. Mark, C. Tosha, 2012, Investigative ophthalmology & visual science.

The distribution of the main intrinsic membrane polypeptide in ocular lens.

D. Bok, J. Horwitz, P. Fitzgerald, 1985, Current eye research.

Bovine epidermal fatty acid-binding protein: determination of ligand specificity and cellular localization in retina and testis.

D. Bok, D. Ong, P. Kingma, 1998, Biochemistry.

Analysis and quantitation of mRNAs encoding the alpha- and beta-subunits of rod photoreceptor cGMP phosphodiesterase in neonatal retinal degeneration (rd) mouse retinas.

J. Phelan, D. Bok, 2000, Experimental eye research.

Complete rescue of photoreceptor dysplasia and degeneration in transgenic retinal degeneration slow (rds) mice

D. Bok, G. Travis, K. Groshan, 1992, Neuron.

Reduced levels of retinyl esters and vitamin A in human renal cancers.

D. Bok, D. Nanus, L. Gudas, 2001, Cancer research.

Repair and replacement to restore sight. Report from the Panel on Photoreceptor/Retinal Pigment Epithelium.

D. Bok, G. Hageman, R. Steinberg, 1993, Archives of ophthalmology.

Downregulation of splicing regulator RBFOX1 compromises visual depth perception

D. Bok, J. Caprioli, Lei Gu, 2018, PloS one.

Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment.

P. Campochiaro, D. Zack, D. Bok, 2002, The American journal of pathology.

Glucose utilization by the retinal pigment epithelium: evidence for rapid uptake and storage in glycogen, followed by glycogen utilization.

Aniq B. Darr, D. Bok, J. Hollyfield, 2006, Experimental eye research.

Differential expression and function of ABCG1 and ABCG4 during development and aging[S]

Greg D. Gale, Paul T. Tarr, Desmond J. Smith, 2010, Journal of Lipid Research.

Investigative Ophthalmology & Visual Science Autoradiographic Localization of Serum Retinol-binding Protein Receptors on the Pigment Epithelium of Dystrophic Rat Retinas

D. Bok, J. Heller, Dean Bok, 2022 .

The distribution of 3H‐Leucine labeled protein in the retinula cells of the crayfish retina

D. Bok, G. Hafner, 1977, The Journal of comparative neurology.

Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration

D. Bok, C. Spencer, M. Radeke, 2011, Proceedings of the National Academy of Sciences.

Restoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degeneration

D. Bok, M. Radeke, L. V. Johnson, 2015, Genome Medicine.

Differential expression of the enzyme that esterifies retinol, lecithin:retinol acyltransferase, in subtypes of human renal cancer and normal kidney.

S. Tickoo, D. Bok, D. Nanus, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Reduced lecithin:retinol acyltransferase expression in human breast cancer.

D. Bok, L. Gudas, R. Rando, 2006, International journal of oncology.

The retina and its disorders

Joseph C. Besharse, Dean Bok, J. Besharse, 2011 .

New insights and new approaches toward the study of age-related macular degeneration

D. Bok, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Neurotrophins enhance retinal pigment epithelial cell survival through neuroprotectin D1 signaling

D. Bok, P. Mukherjee, N. Bazan, 2007, Proceedings of the National Academy of Sciences.

Effect of phytanic acid on cultured retinal pigment epithelium: an in vitro model for Refsum's disease.

P. Bernstein, D. Bok, W. O'day, 1992, Experimental eye research.

Severe Neurologic Impairment in Mice with Targeted Disruption of the Electrogenic Sodium Bicarbonate Cotransporter NBCe2 (Slc4a5 Gene)*

M. Papadopoulos, D. Bok, Li Liu, 2011, The Journal of Biological Chemistry.

Lens-specific expression of recombinant ricin induces developmental defects in the eyes of transgenic mice.

G. Evans, D. Bok, C. Landel, 1988, Genes & development.

Aspartoacylase deficiency affects early postnatal development of oligodendrocytes and myelination

D. Bok, R. Matalon, J. Vellis, 2010, Neurobiology of Disease.

Functional Rescue of Retinal Degeneration-Associated Mutant RPE65 Proteins.

S. Jacobson, D. Bok, Songhua Li, 2016, Advances in experimental medicine and biology.

CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Müller glial cells

D. Bok, S. Nusinowitz, Fei Yu, 2013, Proceedings of the National Academy of Sciences.

Osteonectin/SPARC secreted by RPE and localized to the outer plexiform layer of the monkey retina.

D. Bok, M. Kantorow, I. Rodriguez, 2000, Investigative ophthalmology & visual science.

Renewal of photoreceptor cells.

D. Bok, 1982, Methods in enzymology.

[100] Renewal of photoreceptor cells

D. Bok, 1982 .

Two histidine residues are essential for catalysis by lecithin retinol acyl transferase

D. Bok, R. Rando, M. Mondal, 2001, FEBS letters.

Retinal transplantation and gene therapy. Present realities and future possibilities.

D. Bok, 1993, Investigative ophthalmology & visual science.

Glucose Utilization by Human RPE Cultures

D. Bok, J. Hollyfield, A. Calabro, 2003 .

Functionally intact glutamate-mediated signaling in bipolar cells of the TRKB knockout mouse retina.

R. Marc, D. Schneeweis, D. Bok, 2004, Visual neuroscience.

Electron microscopic localization of [125I]α-bungarotoxin binding sites in the outer plexiform layer of the goldfish retina

D. Bok, I. Schwartz, 1979, Journal of neurocytology.

Genetic analyses of human fetal retinal pigment epithelium gene expression suggest ocular disease mechanisms

Nathan S. Abell, Michael J. Gloudemans, B. Balliu, 2019, Communications Biology.

Arginine‐427 in the Na+/glucose cotransporter (SGLT1) is involved in trafficking to the plasma membrane

E. Wright, D. Bok, B. Hirayama, 1995, FEBS letters.

The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited

Don H. Anderson, M. Hauser, D. Bok, 2010, Progress in Retinal and Eye Research.

Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells.

Tamar Dvash, David S. Williams, D. Bok, 2010, Human Molecular Genetics.

Procion yellow: a marker dye for outer segment disc patency and for rod renewal.

D. Bok, A. Laties, P. Liebman, 1976, Experimental eye research.

Light–dependent Regulation Of The Visual Cycle By Non–photoreceptor Opsins In The RPE Cells

D. Bok, R. Radu, G. Travis, 2004 .

Localization of hydroxyindole-O-methyltransferase in the mammalian pineal gland and retina.

D. Bok, J. Horwitz, A. F. Wiechmann, 1985, Investigative ophthalmology & visual science.

Molecular and cellular alterations induced by sustained expression of ciliary neurotrophic factor in a mouse model of retinitis pigmentosa.

W. Hauswirth, M. Lavail, J. Duncan, 2007, Investigative ophthalmology & visual science.

Diurnal variations in amino acid incorporation into inner segment opsin.

D. Bok, B. Matsumoto, 1984, Investigative ophthalmology & visual science.

A Third Form of the G Protein , 6 Subunit 1

Bernice, D. Bok, Bernard, 2001 .

Gene therapy of retinal dystrophies: achievements, challenges and prospects.

D. Bok, 2004, Novartis Foundation symposium.

Aspartoacylase deficiency affects early postnatal development of oligodendrocytes and myelination

D. Bok, R. Matalon, J. Vellis, 2010, Neurobiology of Disease.

Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease

S. Sarfare, D. Bok, R. Radu, 2017, Proceedings of the National Academy of Sciences.

Immunocytochemical localization of cellular retinol binding protein in the rat retina.

D. Bok, F. Chytil, D. Ong, 1984, Investigative ophthalmology & visual science.