C. Werner

发表

The impact of structure dimensions on initial bacterial adhesion.

R. Helbig, D. Günther, J. Friedrichs, 2016, Biomaterials science.

Hollow fibers made from a poly(3-hydroxybutyrate)/poly-ε-caprolactone blend

C. Werner, H. Brünig, C. Hinüber, 2011 .

3D extracellular matrix interactions modulate tumour cell growth, invasion and angiogenesis in engineered tumour microenvironments.

Anna V. Taubenberger, J. Guck, C. Werner, 2016, Acta biomaterialia.

Amphiphilic Copolymers for Versatile, Facile, and In Situ Tunable Surface Biofunctionalization

J. Friedrichs, C. Werner, L. Renner, 2021, Advanced materials.

Multilayer hydrogel coatings to combine hemocompatibility and antimicrobial activity.

M. Maitz, J. Friedrichs, C. Werner, 2015, Biomaterials.

Standardized microgel beads as elastic cell mechanical probes

Anna V. Taubenberger, J. Guck, C. Werner, 2018, bioRxiv.

3D Microenvironment Stiffness Regulates Tumor Spheroid Growth and Mechanics via p21 and ROCK

J. Guck, C. Werner, T. Kurth, 2019, Advanced biosystems.

3D microenvironment stiffness regulates tumor spheroid growth and mechanics via p21 and ROCK

Anna V. Taubenberger, J. Guck, C. Werner, 2019, bioRxiv.

Combined influence of biophysical and biochemical cues on maintenance and proliferation of hematopoietic stem cells.

C. Werner, E. Müller, M. Bornhäuser, 2017, Biomaterials.

Customizing biohybrid cryogels to serve as ready-to-use delivery systems of signaling proteins.

J. Friedrichs, C. Werner, R. Zimmermann, 2021, Biomaterials.

Biomaterial based strategies to reconstruct the nigrostriatal pathway in organotypic slice co-cultures.

B. Newland, C. Werner, C. Humpel, 2020, Acta biomaterialia.

Tackling Cell Transplantation Anoikis: An Injectable, Shape Memory Cryogel Microcarrier Platform Material for Stem Cell and Neuronal Cell Growth.

B. Newland, C. Werner, A. Rosser, 2015, Small.

Magnetically Controllable Polymer Nanotubes from a Cyclized Crosslinker for Site-Specific Delivery of Doxorubicin

B. Newland, Wenxin Wang, M. Steinhart, 2015, Scientific Reports.

The KIDSTEM European Research Training Network

G. Remuzzi, C. Werner, G. Camussi, 2007, Organogenesis.

Investigation of Sustained BMP Delivery in the Prevention of Medication-Related Osteonecrosis of the Jaw (MRONJ) in a Rat Model.

D. Hutmacher, M. Woodruff, C. Werner, 2019, Macromolecular bioscience.

Periosteum tissue engineering in an orthotopic in vivo platform.

D. Hutmacher, B. Holzapfel, C. Werner, 2017, Biomaterials.

Techniques for RNA extraction from cells cultured in starPEG–heparin hydrogels

L. Haupt, L. Griffiths, C. Werner, 2021, Open Biology.

Macromolecular crowding for tailoring tissue-derived fibrillated matrices.

J. Friedrichs, C. Werner, V. Magno, 2017, Acta biomaterialia.

Cellular reporter systems for high-throughput screening of interactions between bioactive matrices and human mesenchymal stromal cells.

M. Maitz, C. Werner, K. Anastassiadis, 2014, Tissue engineering. Part C, Methods.

Functional Interference in the Bone Marrow Microenvironment by Disseminated Breast Cancer Cells

C. Werner, L. Hofbauer, M. Wobus, 2016, Stem cells.

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

J. Steinbach, C. Werner, Jens Pietzsch, 2017, Oncotarget.

Biomaterials trigger endothelial cell activation when co-incubated with human whole blood.

M. Maitz, C. Werner, Juliane Drichel, 2016, Biomaterials.

Well-Defined Polyethylene Glycol Microscale Hydrogel Blocks Containing Gold Nanorods for Dual Photothermal and Chemotherapeutic Therapy

B. Newland, C. Werner, L. Bray, 2022, Pharmaceutics.

Preclinical Testing of New Hydrogel Materials for Cartilage Repair: Overcoming Fixation Issues in a Large Animal Model

C. Werner, W. Richter, J. Groll, 2021, International journal of biomaterials.

Glycosaminoglycan-based hydrogels with programmable host reactions.

C. Werner, U. Freudenberg, M. Tsurkan, 2019, Biomaterials.

Three-Dimensional In Vitro Hydro- and Cryogel-Based Cell-Culture Models for the Study of Breast-Cancer Metastasis to Bone

C. Werner, L. Bray, M. Binner, 2018, Cancers.

Treatment of Focal Cartilage Defects in Minipigs with Zonal Chondrocyte/Mesenchymal Progenitor Cell Constructs

C. Werner, W. Richter, J. Groll, 2019, International journal of molecular sciences.

A Novel, Low-Volume Method for Organ Culture of Embryonic Kidneys That Allows Development of Cortico-Medullary Anatomical Organization

C. Werner, J. Davies, A. Ofenbauer, 2010, PloS one.

Heparin-based hydrogels induce human renal tubulogenesis in vitro.

C. Werner, V. Magno, U. Freudenberg, 2017, Acta biomaterialia.

Cryogel scaffolds for regionally constrained delivery of lysophosphatidylcholine to central nervous system slice cultures: a model of focal demyelination for multiple sclerosis research.

B. Newland, C. Werner, Anna C. Williams, 2019, Acta biomaterialia.

Altered Structure and Function of Mesenchymal Stromal Cell-Derived Extracellular Matrix in MDS Can be Restored By Luspatercept

C. Werner, M. Wobus, U. Platzbecker, 2019, Blood.

Engineered extracellular matrix components do not alter the immunomodulatory properties of mesenchymal stromal cells in vitro

K. Schäkel, C. Werner, T. Tonn, 2013, Journal of tissue engineering and regenerative medicine.

Tuning the network charge of biohybrid hydrogel matrices to modulate the release of SDF-1

C. Werner, J. Rademann, U. Freudenberg, 2021, Biological chemistry.

Gene‐Expression Profiling of CD34+ Hematopoietic Cells Expanded in a Collagen I Matrix

C. Werner, G. Ehninger, K. Salchert, 2006, Stem cells.

Hierarchically structured nerve guidance channels based on poly-3-hydroxybutyrate enhance oriented axonal outgrowth.

C. Werner, H. Brünig, C. Hinüber, 2014, Acta biomaterialia.

Mesenchymal Stem Cells Can Be Differentiated Into Endothelial Cells In Vitro

Gerhard Ehninger, Martin Bornhäuser, C. Werner, 2004, Stem cells.

Selective vulnerability of inhibitory networks in multiple sclerosis

P. Kind, B. Newland, C. Werner, 2021, Acta Neuropathologica.

Demyelination induces selective vulnerability of inhibitory networks in multiple sclerosis

P. Kind, B. Newland, C. Werner, 2020 .

Sulfonated cryogel scaffolds for focal delivery in ex-vivo brain tissue cultures.

Laura C. Andreae, B. Newland, W. Huttner, 2021, Biomaterials.

Highly Conductive, Stretchable, and Cell-Adhesive Hydrogel by Nanoclay Doping.

V. Busskamp, C. Werner, I. Minev, 2019, Small.

3D Quantification of Vascular-Like Structures in z Stack Confocal Images

C. Werner, E. De‐Juan‐Pardo, L. Bray, 2020, STAR protocols.

Impact of oral astringent stimuli on surface charge and morphology of the protein-rich pellicle at the tooth-saliva interphase.

J. Friedrichs, C. Werner, C. Hannig, 2019, Colloids and surfaces. B, Biointerfaces.

Impact of the springtail's cuticle nanotopography on bioadhesion and biofilm formation in vitro and in the oral cavity

R. Helbig, C. Werner, C. Hannig, 2018, Royal Society Open Science.

Combining Microscopy Assays of Bacteria-Surface Interactions To Better Evaluate Antimicrobial Polymer Coatings

C. Werner, L. Renner, A. Ruland, 2022, Applied and environmental microbiology.

Polymer Hydrogels to Enable New Medical Therapies

C. Werner, M. Nitschke, U. Freudenberg, 2009 .

Intrafibrillar, bone-mimetic collagen mineralization regulates breast cancer cell adhesion and migration.

J. Friedrichs, C. Werner, L. Estroff, 2019, Biomaterials.

Cryogel biomaterials for neuroscience applications

B. Newland, C. Werner, Dimitri Eigel, 2021, Neurochemistry International.

Hybrid Hairy Janus Particles as Building Blocks for Antibiofouling Surfaces.

J. Friedrichs, C. Werner, A. Synytska, 2016, ACS applied materials & interfaces.

Bioresponsive starPEG-heparin hydrogel coatings on vascular stents for enhanced hemocompatibility.

M. Maitz, C. Werner, M. Nitschke, 2021, Materials science & engineering. C, Materials for biological applications.

Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice

C. Werner, J. Simon, U. Freudenberg, 2017, Science Translational Medicine.

Chemokine‐Capturing Wound Contact Layer Rescues Dermal Healing

C. Werner, U. Freudenberg, Lucas Schirmer, 2021, Advanced science.

3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues Aβ42-Induced Loss of Human Neural Stem Cell Plasticity.

J. Friedrichs, C. Werner, T. Kurth, 2018, Developmental cell.

Biofabricated soft network composites for cartilage tissue engineering

Ernst Rank, Stefan Kollmannsberger, Onur Bas, 2017, Biofabrication.

Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments

J. Friedrichs, C. Werner, B. Hoflack, 2013, Nature Methods.

Modular peptide-functionalized gold nanorods for effective glioblastoma multicellular tumor spheroid targeting.

Deric M. Park, C. Werner, C. Werner, 2018, Biomaterials science.

Enhanced targeting of invasive glioblastoma cells by peptide-functionalized gold nanorods in hydrogel-based 3D cultures.

C. Werner, T. Kurth, S. Poser, 2017, Acta biomaterialia.

Static and dynamic 3D culture of neural precursor cells on macroporous cryogel microcarriers

B. Newland, C. Werner, G. Kempermann, 2020, MethodsX.

Stromal fibroblasts regulate microvascular-like network architecture in a bioengineered breast tumour angiogenesis model.

D. Hutmacher, L. Haupt, C. Werner, 2020, Acta biomaterialia.

Neurotropic growth factors and glycosaminoglycan based matrices to induce dopaminergic tissue formation.

C. Werner, A. Storch, U. Freudenberg, 2015, Biomaterials.

Mapping Tumor Spheroid Mechanics in Dependence of 3D Microenvironment Stiffness and Degradability by Brillouin Microscopy

Anna V. Taubenberger, J. Guck, C. Werner, 2021, bioRxiv.

Cryogel-supported stem cell factory for customized sustained release of bispecific antibodies for cancer immunotherapy

Jörg Steinbach, Ralf Bergmann, Nicole Berndt, 2017, Scientific Reports.

A three-dimensional ex vivo tri-culture model mimics cell-cell interactions between acute myeloid leukemia and the vascular niche

C. Werner, M. Bornhäuser, L. Bray, 2017, Haematologica.

three-dimensional vivo model mimics cell-cell

C. Werner, L. Bray, M. Binner, 2017 .

Multi-parametric hydrogels support 3D in vitro bioengineered microenvironment models of tumour angiogenesis.

Jens Friedrichs, Dietmar W Hutmacher, Laura J Bray, 2015, Biomaterials.

Phenotypic, Morphological and Adhesive Differences of Human Hematopoietic Progenitor Cells Cultured on Murine versus Human Mesenchymal Stromal Cells

J. Friedrichs, C. Werner, D. Corbeil, 2015, Scientific Reports.

Soft and flexible poly(ethylene glycol) nanotubes for local drug delivery

B. Newland, M. Steinhart, C. Werner, 2018, Nanoscale.

Polyacrylamide Bead Sensors for in vivo Quantification of Cell-Scale Stress in Zebrafish Development

J. Guck, J. Friedrichs, C. Werner, 2018, Scientific Reports.

Microenvironment-mediated cancer dormancy: Insights from metastability theory

P. Fratzl, C. Werner, A. Cipitria, 2021, Proceedings of the National Academy of Sciences.

Conformational changes of GDNF-derived peptide induced by heparin, heparan sulfate, and sulfated hyaluronic acid - Analysis by circular dichroism spectroscopy and molecular dynamics simulation.

C. Werner, Madhurima Jana, M. Tsurkan, 2021, International journal of biological macromolecules.

Heparin-based, injectable microcarriers for controlled delivery of interleukin-13 to the brain.

B. Newland, C. Werner, A. Rosser, 2020, Biomaterials science.

Synthesis of ROS scavenging microspheres from a dopamine containing poly(β-amino ester) for applications for neurodegenerative disorders.

Hong Zhang, B. Newland, C. Werner, 2016, Biomaterials science.

A hyperbranched dopamine-containing PEG-based polymer for the inhibition of α-synuclein fibrillation

Hong Zhang, B. Newland, Wenxin Wang, 2016, Biochemical and biophysical research communications.

Skin epithelial cells change their mechanics and proliferation upon Snail-mediated EMT signalling

C. Werner, E. Fischer-Friedrich, Annika Frenzel, 2022, bioRxiv.

EMT‐Induced Cell‐Mechanical Changes Enhance Mitotic Rounding Strength

Anna V. Taubenberger, C. Werner, E. Fischer-Friedrich, 2019, bioRxiv.

Tissue-engineered 3D tumor angiogenesis models: potential technologies for anti-cancer drug discovery.

Carsten Werner, Karolina Chwalek, Laura J Bray, 2014, Advanced drug delivery reviews.

Breast cancer cells compete with hematopoietic stem and progenitor cells for intercellular adhesion molecule 1-mediated binding to the bone marrow microenvironment.

J. Friedrichs, C. Werner, M. Wobus, 2016, Carcinogenesis.

StarPEG‐Heparin Hydrogels to Protect and Sustainably Deliver IL‐4

C. Werner, U. Freudenberg, Lucas Schirmer, 2016, Advanced healthcare materials.

Polarization of human hematopoietic progenitors during contact with multipotent mesenchymal stromal cells: effects on proliferation and clonogenicity.

C. Werner, D. Freund, G. Ehninger, 2006, Stem cells and development.

Monoclonal Antibodies 13A4 and AC133 Do Not Recognize the Canine Ortholog of Mouse and Human Stem Cell Antigen Prominin-1 (CD133)

W. Huttner, C. Werner, D. Corbeil, 2016, PloS one.

Bone marrow niche-mimetics modulate HSPC function via integrin signaling

J. Guck, C. Werner, O. Otto, 2017, Scientific Reports.

Space constraints govern fate of hematopoietic stem and progenitor cells in vitro.

C. Werner, E. Müller, C. Waskow, 2015, Biomaterials.

A customizable microfluidic platform for medium-throughput modeling of neuromuscular circuits

Volker Busskamp, Salvatore Girardo, Jessica Bellmann, 2019, Biomaterials.

Cell-derived Bone marrow-mimetics induce erythroid lineage commitment of hematopoietic stem and progenitor cells ex-vivo

C. Werner, A. Jacobi, M. Wobus, 2017 .

Macroporous biohybrid cryogels for co-housing pancreatic islets with mesenchymal stromal cells.

E. Bonifacio, J. Friedrichs, C. Werner, 2016, Acta biomaterialia.

Extracellular matrix deposition of bone marrow stroma enhanced by macromolecular crowding.

J. Friedrichs, C. Werner, M. Bornhäuser, 2015, Biomaterials.

Availability of extracellular matrix biopolymers and differentiation state of human mesenchymal stem cells determine tissue-like growth in vitro.

Cécile M. Bidan, J. Dunlop, P. Fratzl, 2015, Biomaterials.

Overexpression of Jagged-1 and its intracellular domain in human mesenchymal stromal cells differentially affect the interaction with hematopoietic stem and progenitor cells.

C. Werner, K. Anastassiadis, M. Wobus, 2013, Stem cells and development.

MiR-134-mediated β1 integrin expression and function in mesenchymal stem cells.

D. Docheva, M. Schieker, J. Friedrichs, 2013, Biochimica et biophysica acta.

In situ-forming, cell-instructive hydrogels based on glycosaminoglycans with varied sulfation patterns.

C. Werner, R. Zimmermann, U. Freudenberg, 2018, Biomaterials.

Comprehensive characterization of well-defined silk fibroin surfaces: Toward multitechnique studies of surface modification effects.

J. Friedrichs, C. Werner, R. Zimmermann, 2015, Biointerphases.

Cell-instructive starPEG-heparin-collagen composite matrices.

J. Friedrichs, C. Werner, L. Bray, 2017, Acta biomaterialia.

Fabrication of multifunctional titanium surfaces by producing hierarchical surface patterns using laser based ablation methods

R. Helbig, A. Lasagni, C. Werner, 2019, Scientific Reports.

StarPEG/heparin-hydrogel based in vivo engineering of stable bizonal cartilage with a calcified bottom layer

C. Werner, W. Richter, U. Freudenberg, 2018, Biofabrication.

Hollow Poly(3‐hydroxybutyrate) Fibers Produced by Melt Spinning

Harald Brünig, C. Werner, H. Brünig, 2010 .

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds.

M. Maitz, C. Werner, K. Levental, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Focal drug administration via heparin-containing cryogel microcarriers reduces cancer growth and metastasis.

B. Newland, C. Werner, A. Brancale, 2020, Carbohydrate polymers.

Dewaxed ECM: A simple method for analyzing cell behaviour on decellularized extracellular matrices

C. Werner, P. Gruber, A. Ofenbauer, 2015, Journal of tissue engineering and regenerative medicine.

ECM modulated early kidney development in embryonic organ culture.

C. Werner, P. Gruber, A. Ofenbauer, 2013, Biomaterials.

Poly(2‐alkyl‐2‐oxazoline)‐Heparin Hydrogels—Expanding the Physicochemical Parameter Space of Biohybrid Materials

M. Maitz, C. Werner, R. Jordan, 2021, Advanced healthcare materials.

Evaluation of Three-Dimensional in Vitro Models to Study Tumor Angiogenesis.

C. Werner, L. Bray, 2017, ACS biomaterials science & engineering.

Multiphasic microgel-in-gel materials to recapitulate cellular mesoenvironments in vitro.

J. Friedrichs, C. Werner, J. Thiele, 2019, Biomaterials science.

Macroporous heparin-based microcarriers allow long-term 3D culture and differentiation of neural precursor cells.

B. Newland, C. Werner, G. Kempermann, 2019, Biomaterials.

Geometry-Driven Cell Organization Determines Tissue Growths in Scaffold Pores: Consequences for Fibronectin Organization

Georg N. Duda, Ansgar Petersen, C. Werner, 2013, PloS one.

Discriminant Principal Component Analysis of ToF‐SIMS Spectra for Deciphering Compositional Differences of MSC‐Secreted Extracellular Matrices

C. Werner, R. Zimmermann, M. Wobus, 2023, Small methods.

Poly(ethylene glycol) based nanotubes for tuneable drug delivery to glioblastoma multiforme

B. Newland, Wenxin Wang, C. Werner, 2020, Nanoscale advances.

Layer-by-Layer Assembly of Heparin and Peptide-Polyethylene Glycol Conjugates to Form Hybrid Nanothin Films of Biomatrices.

M. Bickle, J. Friedrichs, C. Werner, 2018, ACS applied materials & interfaces.

Sustained Release of Human Adipose Tissue Stem Cell Secretome from Star‐Shaped Poly(ethylene glycol) Glycosaminoglycan Hydrogels Promotes Motor Improvements after Complete Transection in Spinal Cord Injury Rat Model

A. Salgado, C. Werner, R. A. Sousa, 2023, Advanced Healthcare Materials.

Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi‐walled carbon nanotubes

B. Newland, Wenxin Wang, M. Steinhart, 2016, Journal of interdisciplinary nanomedicine.

Injectable Glycosaminoglycan-Based Cryogels from Well-Defined Microscale Templates for Local Growth Factor Delivery

B. Newland, Wenxin Wang, C. Werner, 2021, ACS chemical neuroscience.

Oxygen producing microscale spheres affect cell survival in conditions of oxygen-glucose deprivation in a cell specific manner: implications for cell transplantation† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8bm00490k

B. Newland, C. Werner, A. Rosser, 2018, Biomaterials science.

Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease

R. Mayeux, C. Werner, B. Vardarajan, 2023, NPJ Regenerative medicine.

Limbal stromal cells derived from porcine tissue demonstrate mesenchymal characteristics in vitro

C. Werner, Julia Fernández-Pérez, L. Bray, 2017, Scientific Reports.

Zwitterionic Peptides Reduce Accumulation of Marine and Freshwater Biofilm Formers.

A. Rosenhahn, C. Werner, J. Bandow, 2021, ACS applied materials & interfaces.

Peptide‐functionalized starPEG/heparin hydrogels direct mitogenicity, cell morphology and cartilage matrix distribution in vitro and in vivo

C. Werner, W. Richter, M. Binner, 2018, Journal of tissue engineering and regenerative medicine.

Providing the right cues in nerve guidance conduits: Biofunctionalization versus fiber profile to facilitate oriented neuronal outgrowth.

C. Werner, H. Brünig, C. Hinüber, 2016, Materials science & engineering. C, Materials for biological applications.

Oxygen-Producing Gellan Gum Hydrogels for Dual Delivery of Either Oxygen or Peroxide with Doxorubicin.

B. Newland, C. Werner, Dimitri Eigel, 2017, ACS biomaterials science & engineering.

Direct laser interference patterning for decreased bacterial attachment

Andrés F. Lasagni, Ralf Helbig, Carmen Gil, 2016, SPIE LASE.