Lei Chang

发表

Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease.

C. Mirkin, E. Mufson, D. Georganopoulou, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Single-Molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations

David M. Rissin, D. Walt, D. Duffy, 2010, Nature Biotechnology.

Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss

C. Finch, Lei Chang, W. Klein, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Detection of a biomarker for Alzheimer's disease from synthetic and clinical samples using a nanoscale optical biosensor.

R. V. Van Duyne, Lei Chang, W. Klein, 2005, Journal of the American Chemical Society.

Monoclonal antibodies that target pathological assemblies of Aβ

E. Bigio, Lei Chang, W. Klein, 2007, Journal of neurochemistry.

Hypoxia Due to Cardiac Arrest Induces a Time-Dependent Increase in Serum Amyloid β Levels in Humans

Henrik Zetterberg, Kaj Blennow, David C. Duffy, 2011, PloS one.

Fully automated ultrasensitive digital immunoassay for cardiac troponin I based on single molecule array technology.

Lei Chang, V. Melenovský, P. Jarolim, 2015, Clinical chemistry.

Inhibitors of tissue-nonspecific alkaline phosphatase: design, synthesis, kinetics, biomineralization and cellular tests.

Lei Chang, F. Popowycz, D. Magne, 2013, Bioorganic & medicinal chemistry.

COMPARISON OF TWO PLATFORMS QUANTITATING FG/ML NEUROLOGICAL BIOMARKERS USING SINGLE MOLECULE ARRAYS AND DIGITAL ELISA: THE BENCHTOP READER SR-X™ AND THE FULLY AUTOMATED ANALYZER HD-1™

David M. Rissin, Lei Chang, J. Lambert, 2018, Alzheimer's & Dementia.

Per-6-substituted β-cyclodextrin libraries inhibit formation of β-amyloid-peptide (Aβ)-derived, soluble oligomers

Lei Chang, W. Klein, D. Venton, 2002, Journal of Molecular Neuroscience.

Survey of External Quality Assessment Scheme for Blood Bank Laboratories in Taiwan

Lei Chang, C. Kao, D. Lin, 2011 .

Antimicrobial efficacy of Propolis, Morinda citrifolia, Azadirachta indica (Neem) against Actinomyces Radicidentis: Invitro study

Lei Chang, Syed Sadaqat Shah, S. Pan, 2019, Biomedical Research.

Screening and characterization of a cellulase with endocellulase and exocellulase activity from yak rumen metagenome

Lei Chang, Qiang Huang, Jungang Zhou, 2011 .

Cloning and Characterization of Two β-Glucosidase/Xylosidase Enzymes from Yak Rumen Metagenome

Lei Chang, Qiang Huang, Jungang Zhou, 2011, Applied Biochemistry and Biotechnology.

Imidazopyridine- and purine-thioacetamide derivatives: potent inhibitors of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1).

C. Müller, P. Herdewijn, J. Rozenski, 2014, Journal of medicinal chemistry.

Characterization of a bifunctional xylanase/endoglucanase from yak rumen microorganisms

Lei Chang, Jungang Zhou, Hong Lu, 2011, Applied Microbiology and Biotechnology.

Biochemical and kinetic characterization of GH43 β-d-xylosidase/α-l-arabinofuranosidase and GH30 α-l-arabinofuranosidase/β-d-xylosidase from rumen metagenome

Lei Chang, Jungang Zhou, Hong Lu, 2011, Journal of Industrial Microbiology & Biotechnology.

Synaptic Targeting by Alzheimer's-Related Amyloid β Oligomers

C. Finch, E. Bigio, Lei Chang, 2004, The Journal of Neuroscience.

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

C. Finch, E. Bigio, Lei Chang, 2004, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Fifth-generation digital immunoassay for prostate-specific antigen by single molecule array technology.

Lori J Sokoll, David H Wilson, Alan W Partin, 2011, Clinical chemistry.

Synthesis and evaluation of benzo[b]thiophene derivatives as inhibitors of alkaline phosphatases.

Lei Chang, R. Buchet, M. Lemaire, 2009, Bioorganic & medicinal chemistry.

Synthesis and evaluation of thiophenyl derivatives as inhibitors of alkaline phosphatase.

Lei Chang, F. Popowycz, R. Buchet, 2011, Bioorganic & medicinal chemistry letters.

A Localized Surface Plasmon Resonance Biosensor: First Steps toward an Assay for Alzheimer's Disease

W. P. Hall, R. V. Van Duyne, Lei Chang, 2004 .

Self-assembly of Aβ1-42 into globular neurotoxins

C. Finch, Lei Chang, W. Klein, 2003 .

Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1

M. Ohno, J. Disterhoft, Lei Chang, 2006, The European journal of neuroscience.

N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection

Joseph M. Johnson, Lei Chang, J. Nattermann, 2021, Nature Communications.

Selective Inhibitors of Cyclin G Associated Kinase (GAK) as Anti-Hepatitis C Agents.

S. Knapp, P. Herdewijn, Lei Chang, 2015, Journal of medicinal chemistry.

Rapid, Fully Automated Digital Immunoassay for p24 Protein with the Sensitivity of Nucleic Acid Amplification for Detecting Acute HIV Infection.

Lei Chang, M. Busch, M. Stone, 2015, Clinical chemistry.

Simple diffusion-constrained immunoassay for p24 protein with the sensitivity of nucleic acid amplification for detecting acute HIV infection.

David H Wilson, Linan Song, Cheuk W Kan, 2013, Journal of virological methods.

The Simoa HD-1 Analyzer

David H Wilson, Tomasz Piech, David M. Rissin, 2016, Journal of laboratory automation.

Single molecule measurements of tumor necrosis factor α and interleukin-6 in the plasma of patients with Crohn's disease.

David H Wilson, Linan Song, Cheuk W Kan, 2011, Journal of immunological methods.

Single molecule enzyme-linked immunosorbent assays: theoretical considerations.

David H Wilson, David M. Rissin, David M Rissin, 2012, Journal of immunological methods.

Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Aβ oligomerization

J. D. Figueroa-Villar, Lei Chang, S. Ferreira, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies

T. Morgan, C. Finch, Lei Chang, 2001, Journal of neurochemistry.

Per-6-substituted-per-6-deoxy β-cyclodextrins Inhibit the Formation of β-Amyloid Peptide Derived Soluble Oligomers

Lei Chang, W. Klein, D. Venton, 2004 .

Self-assembly of Abeta(1-42) into globular neurotoxins.

C. Finch, Lei Chang, W. Klein, 2003, Biochemistry.

PGH2‐derived levuglandin adducts increase the neurotoxicity of amyloid β1–42

T. Montine, O. Boutaud, J. Oates, 2006, Journal of neurochemistry.

Per-6-substituted-per-6-deoxy beta-cyclodextrins inhibit the formation of beta-amyloid peptide derived soluble oligomers.

Lei Chang, W. Klein, D. Venton, 2004, Journal of medicinal chemistry.

Per-6-substituted beta-cyclodextrin libraries inhibit formation of beta-amyloid-peptide (A beta)-derived, soluble oligomers.

Lei Chang, W. Klein, D. Venton, 2002, Journal of molecular neuroscience : MN.

Femtomole immunodetection of synthetic and endogenous amyloid-β oligomers and its application to Alzheimer’s disease drug candidate screening

Lei Chang, W. Klein, D. Venton, 2007, Journal of Molecular Neuroscience.

Development of an ultrasensitive multiplex assay for simultaneous detection of Aβ1‐42, Aβ1‐40, GFAP and NF‐L in blood

W. M. van der Flier, Lei Chang, C. Teunissen, 2020 .

Rapid, Fully Automated Digital Immunoassay for p24 Protein with the Sensitivity of Nucleic Acid Amplification for Detecting Acute HIV Infection.

Lei Chang, M. Busch, M. Stone, 2015, Clinical chemistry.

Synthesis and evaluation of benzo[b]thiophene derivatives as inhibitors of alkaline phosphatases.

Lei Chang, R. Buchet, M. Lemaire, 2009, Bioorganic & medicinal chemistry.

Highly enantioselective hydrolysis of phenyl-1,2-ethanediol cyclic carbonates by newly isolated Bacillus sp. ECU0015

Lei Chang, Jiang Pan, Jian‐He Xu, 2010 .

Synthesis and evaluation of thiophenyl derivatives as inhibitors of alkaline phosphatase.

Lei Chang, F. Popowycz, R. Buchet, 2011, Bioorganic & medicinal chemistry letters.