J. Testa

J. Siegfried, J. Testa, P. Keohavong, 1997, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Detection of low‐fraction K‐ras mutations in primary lung tumors using a sensitive method

J. Luketich, J. Siegfried, J. Testa, 1997, International journal of cancer.

The human calcitonin gene is located on the short arm of chromosome 11.

S. Baylin, J. Testa, O. Mcbride, 1984, Biochemical and biophysical research communications.

Homozygous deletions within 9p21-p22 identify a small critical region of chromosomal loss in human malignant mesotheliomas.

J. Cheng, S. Jhanwar, J. Testa, 1993, Cancer research.

Philadelphia Chromosome Symposium: commemoration of the 50th anniversary of the discovery of the Ph chromosome.

P. Nowell, J. Rowley, N. Heisterkamp, 2011, Cancer genetics.

The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential.

J. Testa, T. Franke, P. Tsichlis, 1993, Oncogene.

Mesothelioma Mouse Models with Mixed Genomic States of Chromosome and Microsatellite Instability

R. Shoemaker, J. Testa, S. Difilippantonio, 2022, Cancers.

ANNOUNCEMENTS

S. Franceschi, N. Kamada, J. Testa, 1985 .

Exfoliative cytologic evaluation of primary cultured lung carcinomas

J. Testa, J. Resau, I. Miura, 1991, Cytotechnology.

Chromosome alterations in human small cell lung cancer: frequent involvement of 5q.

J. Testa, L. Doyle, I. Miura, 1992, Cancer research.

Expression of GPC3, an X-linked recessive overgrowth gene, is silenced in malignant mesothelioma

S. Jhanwar, J. Testa, A. Rienzo, 2000, Oncogene.

Murine mantle cell lymphoma model cell line

J. Testa, F. Jin, M. Slifker, 2013, Leukemia.

Chromosome alterations in 21 non‐small cell lung carcinomas

J. Siegfried, J. Testa, J. Resau, 1990, Genes, chromosomes & cancer.

Neurofibromatosis 2 and malignant mesothelioma.

L. Pitts, J. Testa, A. De Rienzo, 2002, Neurology.

Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells.

D. Bell, J. Testa, K. Tew, 1998, Cancer research.

AKT signaling in normal and malignant cells

J. Testa, P. Tsichlis, 2005, Oncogene.

Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene.

J. Testa, C. Kozak, D. Altomare, 1996, Cytogenetics and Cell Genetics.

Mapping of AKT3, encoding a member of the Akt/protein kinase B family, to human and rodent chromosomes by fluorescence in situ hybridization

J. Testa, T. Taguchi, A. Tosolini, 2000, Cytogenetic and Genome Research.

Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts.

J. Testa, S. Kasayama, S. Sumitani, 2002, Endocrinology.

Activation of Akt2 Inhibits anoikis and apoptosis induced by myogenic differentiation

J. Testa, Y. Fujio, K. Walsh, 2001, Cell Death and Differentiation.

Molecular cloning and localization of the human GAX gene to 7p21.

J. Testa, K. Walsh, D. Altomare, 1994, Genomics.

Losses of Both Products of the Cdkn2a/Arf Locus Contribute to Asbestos-Induced Mesothelioma Development and Cooperate to Accelerate Tumorigenesis

J. Testa, Jinfei Xu, M. Carbone, 2011, PloS one.

Isolated BAP1 loss in malignant pleural mesothelioma predicts immunogenicity with implications for immunotherapeutic response

J. Testa, H. Osmanbeyoglu, E. Sementino, 2022, bioRxiv.

Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma

S. Jhanwar, J. Testa, R. Flores, 2020, Clinical Cancer Research.

BAP1, a tumor suppressor gene driving malignant mesothelioma.

J. Testa, M. Cheung, 2017, Translational lung cancer research.

In fl ammation-Related IL 1 b / IL 1 R Signaling Promotes the Development of Asbestos-Induced Malignant Mesothelioma

J. Testa, B. Mossman, A. Shukla, 2016 .

J. Testa, B. Mossman, A. Shukla, 2016, Cancer Prevention Research.

An asbestos-exposed family with multiple cases of pleural malignant mesothelioma without inheritance of a predisposing BAP1 mutation.

P. Visca, J. Testa, F. Facciolo, 2015, Cancer genetics.

Germline BAP1 mutation in a family with high incidence of multiple primary cancers and a potential gene-environment interaction.

J. Testa, J. Ohar, Yuwaraj Kadariya, 2015, Cancer letters.

c-Met Axis − miR-34 a − Mesotheliomas with Enriched Cancer Stem Cells via a p 53 Tumor Suppressor Alterations Cooperate to Drive Aggressive

Yue Wu, J. Testa, V. Kolev, 2014 .

Germline Mutation of Bap 1 in a Mouse Model Accelerates Development of Asbestos-Induced Malignant Mesothelioma

J. Testa, S. Litwin, Yinfei Tan, 2014 .

Tumor suppressor alterations cooperate to drive aggressive mesotheliomas with enriched cancer stem cells via a p53-miR-34a-c-Met axis.

Yue Wu, J. Testa, V. Kolev, 2014, Cancer research.

Further evidence for germline BAP1 mutations predisposing to melanoma and malignant mesothelioma.

J. Testa, M. Cheung, L. Penney, 2013, Cancer genetics.

Deletion mapping of the short arm of chromosome 3 in human malignant mesothelioma

J. Cheng, S. Jhanwar, J. Testa, 1994, Genes, chromosomes & cancer.

Malignant Mesothelioma: An Asbestos Legacy

J. Testa, 2017 .

Serine/Threonine Kinase AKT Is Frequently Activated in Human Bile Duct Cancer and Is Associated with Increased Radioresistance

T. Okumura, J. Testa, Y. Kohgo, 2004, Cancer Research.

DLX Genes: Roles in Development and Cancer

J. Testa, Yinfei Tan, 2021, Cancers.

Absence of post‐transcriptional RNA modifications of BCL10 in human malignant mesothelioma and colorectal cancer

S. Jhanwar, J. Testa, S. Apostolou, 2001, Genes, chromosomes & cancer.

Wnt signaling mediates oncogenic synergy between Akt and Dlx5 in T-cell lymphomagenesis by enhancing cholesterol synthesis

J. Testa, Yinfei Tan, E. Sementino, 2020, Scientific Reports.

FAS-Associated Factor 1 (FAF1): Diverse functions and implications for oncogenesis

J. Testa, D. Altomare, C. Menges, 2009, Cell cycle.

Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer.

A. Knudson, J. Testa, O. Hino, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene.

A. Knudson, J. Testa, G. Xiao, 1994, Proceedings of the National Academy of Sciences of the United States of America.

High molecular weight DNA from fixed cytogenetic preparations.

J. Testa, P. Barker, N. Parsa, 1986, American journal of human genetics.

Membrane translocation and activation of the Akt kinase in growth factor-stimulated hematopoietic cells.

J. Testa, A. Bellacosa, 1997, Leukemia research.

Loss of heterozygosity analysis of 13q and 14q in human malignant mesothelioma

S. Jhanwar, J. Testa, A. De Rienzo, 2000, Genes, chromosomes & cancer.

The AKT1 proto-oncogene maps to human chromosome 14, band q32.

C. Croce, K. Huebner, J. Testa, 1988, Genomics.

Chromosomal localization of a gene, GF1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents.

C. Gilks, N. Copeland, D. Gilbert, 1995, Cytogenetics and cell genetics.

GIPC Is Recruited by APPL to Peripheral TrkA Endosomes and Regulates TrkA Trafﬁcking and Signaling (cid:1)

J. Yates, M. Dong, J. Testa, 2006 .

Translocation and activation of AKT2 in response to stimulation by insulin

Steven W. Johnson, J. Testa, Y. Mitsuuchi, 1998, Journal of cellular biochemistry.

Susceptibility to renal carcinoma in the Eker rat involves a tumor suppressor gene on chromosome 10.

A. Knudson, K. Buetow, J. Testa, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Localization of the interferon-α gene cluster to rat chromosome bands 5q31→q33 by fluorescence in situ hybridization

A. Knudson, J. Testa, T. Taguchi, 1992 .

Localization of the interferon-alpha gene cluster to rat chromosome bands 5q31----q33 by fluorescence in situ hybridization.

A. Knudson, J. Testa, T. Taguchi, 1992, Cytogenetics and cell genetics.

Cyclin T2A Gene Maps on Human Chromosome 2q21

J. Testa, A. Giordano, A. Baldi, 2001, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Recurrent lymphangiomyomatosis after transplantation: genetic analyses reveal a metastatic mechanism.

J. Testa, T. Colby, E. Henske, 2003, American journal of respiratory and critical care medicine.

HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway.

H. Pass, J. Testa, M. Carbone, 2008, American journal of respiratory cell and molecular biology.

Identification and mapping of human histone acetylation modifier gene homologues.

A. Feinberg, D. Bell, J. Testa, 1998, Genomics.

Cloning of a Putative Ligand for the T1/ST2 Receptor (*)

M. Gayle, J. Testa, S. Dower, 1996, The Journal of Biological Chemistry.

Loss of heterozygosity analysis defines a 3-cM region of 15q commonly deleted in human malignant mesothelioma

S. Jhanwar, J. Testa, A. Rienzo, 2001, Oncogene.

Prolonged subcutaneous administration of recombinant α2b interferon in patients with previously untreated Philadelphia chromosome-positive chronic-phase chronic myelogenous leukemia: Effect on remission duration and survival: Cancer and leukemia group B study 8583

C. Bloomfield, J. Testa, S. George, 1993 .

Hypereosinophilic syndrome with evolution to myeloproliferative disorder: temporal relationship to loss of Y chromosome and c-N-ras activation.

S. Mane, J. Testa, J. Gutheil, 1990, Hematologic pathology.

Genomic Copy Number Alterations in Renal Cell Carcinoma with Sarcomatoid Features.

J. Testa, R. Uzzo, Philip H. Abbosh, 2015, The Journal of urology.

A multi-institutional study confirms the presence and expression of simian virus 40 in human malignant mesotheliomas.

V. Rusch, J. Testa, K. Khalili, 1998, Cancer research.

Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model

H. Pass, J. Testa, M. Carbone, 2010, Annals of the New York Academy of Sciences.

Spontaneous transformation of the ovarian surface epithelium and the biology of ovarian cancer

R. Ozols, A. Godwin, J. Testa, 1995 .

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells

J. Testa, S. Albelda, Yuwaraj Kadariya, 2022, International journal of molecular sciences.

Genetic-susceptibility factor and malignant mesothelioma in the Cappadocian region of Turkey

J. Testa, S. Emri, M. Carbone, 2001, The Lancet.

BAP1 maintains HIF-dependent interferon beta induction to suppress tumor growth in clear cell renal cell carcinoma.

B. Leiby, J. Testa, R. Uzzo, 2022, Cancer letters.

Frequent activation of AKT2 kinase in human pancreatic carcinomas

J. Testa, A. De Rienzo, J. Hoffman, 2002, Journal of cellular biochemistry.

Potential Role of mTORC2 as a Therapeutic Target in Clear Cell Carcinoma of the Ovary

J. Testa, S. Mabuchi, H. Kurachi, 2013, Molecular Cancer Therapeutics.

Companion Diagnostics and Cancer Biomarkers Potential Role of mTORC 2 as a Therapeutic Target in Clear Cell Carcinoma of the Ovary

J. Testa, S. Mabuchi, H. Kurachi, 2013 .

A Clue to the Therapy of Neurofibromatosis Type 2: NF2/Merlin Is a PAK1 Inhibitor

J. Testa, M. Giovannini, G. Xiao, 2004, Cancer journal.

HighMolecular WeightDNA fromFixed Cytogenetic Preparations

J. Testa, P. Barker, N. Parsa, 1986 .

Co-targeting of Akt and Myc inhibits viability of lymphoma cells from Lck-Dlx5 mice

J. Testa, Yinfei Tan, Yuwaraj Kadariya, 2015, Cancer biology & therapy.

Upregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling.

A. Godwin, J. Testa, Yinfei Tan, 2010, Cancer research.

The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells

James S. Duncan, J. Testa, A. Bellacosa, 2022, Science Signaling.

The pattern and clinical significance of karyotypic abnormalities in patients with idiopathic and postpolycythemic myelofibrosis

J. Rowley, J. Testa, J. Miller, 1985, Cancer.

Chromosomal DNA cytophotometry in 20q- nonspecific myeloid disorders.

J. Rowley, A. Carrano, L. Ashworth, 1979, Cancer research.

Chromosomal alterations in acute leukemia patients studied with improved culture methods.

J. Testa, S. Misawa, P. Wiernik, 1985, Cancer research.

Advances in Brief Loss of Heterozygosity Analysis Defines a Critical Region in Chromosome Ip 22 Commonly Deleted in Human Malignant Mesothelioma 1

S. Jhanwar, J. Testa, B. Balsara, 2006 .

Evolution of karyotypes in acute nonlymphocytic leukemia.

J. Rowley, J. Testa, J. Vardiman, 1979, Cancer research.

Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma.

J. Testa, D. Wiest, Shuyun Rao, 2016, Cancer research.

Absence of BCL10 Mutations in Human Malignant Mesothelioma

S. Jhanwar, J. Testa, A. Rienzo, 1999, Cell.

Localization of the proto-oncogene MOS to 8q11-q12 by in situ chromosomal hybridization.

M. L. Le Beau, G. V. Vande Woude, J. Testa, 1988, Genomics.

Promyelocytic blast crisis in chronic granulocytic leukemia with 15;17 translocation.

J. Testa, S. Misawa, C. Schiffer, 1984, Leukemia research.

B cells malignantly transformed by human immunodeficiency virus are polyclonal.

J. Testa, S. Astrin, G. Sonoda, 1998, Virology.

Perturbations of the AKT signaling pathway in human cancer

J. Testa, Deborah A Altomare, Joseph R Testa, 2005, Oncogene.

AKT3 (v-akt murine thymoma viral oncogene homolog 3, Protein Kinase B gamma)

J. Testa, M. Cheung, 2011 .

GSK690693 Delays Tumor Onset and Progression in Genetically Defined Mouse Models Expressing Activated Akt

J. Testa, Rakesh Kumar, A. Di Cristofano, 2010, Clinical Cancer Research.

Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E.

K. Shokat, M. Feldman, A. Hsieh, 2010, Cancer cell.

Activation of p21-Activated Kinase 2 by Human Immunodeficiency Virus Type 1 Nef Induces Merlin Phosphorylation

J. Testa, V. Arora, J. Garcia, 2005, Journal of Virology.

Retroviral-like sequences specifically expressed in the rat ovary detect genetic differences between normal and transformed rat ovarian surface epithelial cells.

A. Godwin, J. Testa, T. Hamilton, 1995, Endocrinology.

RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer.

J. Testa, S. Litwin, S. Mabuchi, 2007, Cancer research.

egulation of DLX5 Promotes Ovarian Cancer Cell

A. Godwin, J. Testa, M. Cheung, 2010 .

Induction of terminal differentiation and nuclear appendage(s) formation in a human myeloid leukaemia cell line (HL-60).

J. Testa, N. Parsa, A. B. Mukherjee, 1985, Cytobios.

Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways.

G. V. Vande Woude, J. Testa, G. Woude, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Identification and Characterization of Putative Tumor Suppressor NGB, a GTP-Binding Protein That Interacts with the Neurofibromatosis 2 Protein

D. Coppola, S. Nicosia, J. Cheng, 2007, Molecular and Cellular Biology.

Spontaneous transformation of rat ovarian surface epithelial cells results in well to poorly differentiated tumors with a parallel range of cytogenetic complexity.

A. Godwin, J. Testa, T. Hamilton, 1994, Cancer research.

Disregulated expression of the transcription factor ThPOK during T-cell development leads to high incidence of T-cell lymphomas

A. Ferrando, M. Sulis, J. Testa, 2015, Proceedings of the National Academy of Sciences.

Coexisting myelodysplasia and myeloproliferative features in a single clone containing 5q-, Ph and i(17q).

J. Testa, T. Al-Saleem, M. Smith, 1999, Leukemia research.

Loss of chromosomes 1 and X in a renal oncocytoma: implications for a possible pseudoautosomal tumor suppressor locus.

J. Testa, R. Greenberg, S. Apostolou, 2000, Cancer genetics and cytogenetics.

Cytogenetic findings in a breast stromal sarcoma. Application of fluorescence in situ hybridization to characterize the breakpoint regions in an 11;19 translocation.

J. Palazzo, J. Testa, T. Taguchi, 1992, Cancer genetics and cytogenetics.

Amplification of the c-myc oncogene is associated with an abnormally banded region on chromosome 8 or double minute chromosomes in two HL-60 human leukemia sublines.

J. Testa, S. Misawa, S. Staal, 1987, Cancer genetics and cytogenetics.

Fluorescent bodies in lymphocytes in chronic lymphocytic leukemia.

J. Testa, M. Murtha, D. Hogge, 1985, Cancer genetics and cytogenetics.

Unusual karyotypic changes and B cell involvement in a case of lymph node blast crisis of chronic myelogenous leukemia.

J. Testa, S. Misawa, C. Schiffer, 1984, Blood.

BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance

G. Gupta, J. Testa, X. Hua, 2018, Cell reports.

Isolation, characterization, and mapping to human chromosome 11q24-25 of a cDNA encoding a highly conserved putative transmembrane protein, TMC.

J. Testa, A. Bellacosa, N. A. Lissy, 1996, Biochimica et biophysica acta.

Acute eosinophilic leukemia with a (10;11) chromosomal translocation.

J. Testa, C. Schiffer, S. Fischkoff, 1988, Leukemia.

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.

J. Cheng, J. Testa, D. Watson, 1996, Proceedings of the National Academy of Sciences of the United States of America.

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.

J. Cheng, A. Godwin, J. Testa, 1992, Proceedings of the National Academy of Sciences of the United States of America.

SV40 and cell cycle perturbations in malignant mesothelioma.

J. Testa, A. Giordano, Joseph R. Testa, 2001, Seminars in cancer biology.

Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis

J. Cheng, J. Testa, G. Kruh, 1997, Oncogene.

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

J. Cheng, D. Bell, A. Godwin, 1995, International journal of cancer.

Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas

J. Cheng, J. Testa, B. Ruggeri, 1998, Molecular carcinogenesis.

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region.

J. Testa, P. Tsichlis, A. Bellacosa, 1991, Science.

Genetic alterations in mesothelioma pathogenesis

S. Jhanwar, J. Testa, 2008 .

Detection of SV40 DNA sequences in malignant mesothelioma specimens from the United States, but not from Turkey

J. Testa, A. De Rienzo, D. Sterman, 2002, Journal of cellular biochemistry.

Data supporting the roles of BAP1, STING, and IFN-β in ISGF3 activation in ccRCC

Wei Jiang, J. Testa, Z. Zhong, 2022, Data in brief.

p53 mutations, ras mutations, and p53-heat shock 70 protein complexes in human lung carcinoma cell lines.

R. Metcalf, E. Appella, J. Testa, 1991, Cancer research.

Dicentric chromosome 17 in patients with leukemia.

J. Testa, B. C. Cohen, 1986, Cancer genetics and cytogenetics.

Erratum: BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance (Cell reports (2018) 24 13 (3513-3527.e7) PII: S2211-1247(18)31572-9)

G. Gupta, J. Testa, X. Hua, 2018 .

Genetic susceptibility and familial malignant mesothelioma

J. Testa, M. Carbone, 2001, The Lancet.

Correlation of occupation and karyotype in adults with acute nonlymphocytic leukemia.

J. Rowley, J. Testa, J. Vardiman, 1982, Blood.

Prolonged subcutaneous administration of recombinant alpha 2b interferon in patients with previously untreated Philadelphia chromosome-positive chronic-phase chronic myelogenous leukemia: effect on remission duration and survival: Cancer and Leukemia Group B study 8583.

C. Bloomfield, J. Testa, S. George, 1993, Blood.

The significance of CD34 and TdT determinations in patients with untreated de novo acute myeloid leukemia.

J. Testa, J. Yang, C. Schiffer, 1992, Leukemia.

Emerging translational therapies for mesothelioma.

H. Pass, J. Testa, M. Carbone, 1999, Chest.

Cytogenetic patterns in polycythemia vera

J. Testa, 1980 .

leukemia The bcr gene in Philadelphia chromosome positive acute lymphoblastic

S. Thibodeau, J. Groffen, J. Testa, 2005 .

The bcr Gene in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

S. Thibodeau, N. Heisterkamp, J. Groffen, 1989 .

The bcr gene in Philadelphia chromosome positive acute lymphoblastic leukemia.

S. Thibodeau, N. Heisterkamp, J. Groffen, 1989, Blood.

Application of ethidium bromide for high-resolution banding analysis of chromosomes from human malignant cells.

J. Testa, T. Tomiyasu, 1988, Stain technology.

Cancer esearch cular and Cellular Pathobiology egulation of DLX 5 Promotes Ovarian Cancer Cell R liferation by Enhancing IRS-2-AKT Signaling

A. Godwin, J. Testa, M. Cheung, 2010 .

Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells

J. Testa, B. Tang, W. Kruger, 2012, Cancer biology & therapy.

Human annexin 31 genetic mapping and origin.

D. Bell, J. Testa, M. P. Fernández, 1999, Gene.

Genomic locations of ANX11 and ANX13 and the evolutionary genetics of human annexins.

D. Bell, J. Testa, M. P. Fernández, 1998, Genomics.

Asbestos and Other Hazardous Fibrous Minerals: Potential Exposure Pathways and Associated Health Risks

J. Testa, E. Belluso, R. Gieré, 2022, International journal of environmental research and public health.

Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice

J. Testa, W. Hwang, S. Albelda, 2015, Carcinogenesis.

Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B.

A. Look, J. Testa, Rugang Zhang, 2012, Blood.

Recent advances in the molecular analysis of human malignant mesothelioma.

J. Testa, A. De Rienzo, 2000, La Clinica terapeutica.

Asbestos, chromosomal deletions, and tumor suppressor gene alterations in human malignant mesothelioma

J. Testa, S S Murthy, J R Testa, 1999, Journal of cellular physiology.

Diverse mechanisms of AKT pathway activation in human malignancy.

J. Testa, M. Cheung, Joseph R Testa, 2013, Current cancer drug targets.

The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas.

S. Thorgeirsson, D. Bell, J. Testa, 2000, The American journal of pathology.

Methods of processing marrow samples may affect the frequency of detectable aneuploid cells

J. Rowley, J. Testa, M. Waghray, 1981, American journal of hematology.

Cellular and molecular parameters of mesothelioma

H. Pass, J. Testa, M. Carbone, 2006, Journal of cellular biochemistry.

Chromosome abnormalities in malignant hematologic diseases.

J. Rowley, J. Testa, Joseph R. Testa, 1982, Advances in cancer research.

Correlation of clinical findings with quinacrine-banded chromosomes in 90 adults with acute nonlymphocytic leukemia: an eight-year study (1970-1977).

J. Rowley, J. Testa, J. Vardiman, 1978, The New England journal of medicine.

GIPC Is Recruited by APPL to Peripheral TrkA Endosomes and Regulates TrkA Trafficking and Signaling

John R. Yates, Meng-Qiu Dong, J. Yates, 2006, Molecular and Cellular Biology.

Cytotoxic and cytodifferentiative components of 6-thioguanine resistance in HL-60 cells containing acquired double minute chromosomes.

J. Testa, R. Gallagher, A. Ferrari, 1984, Cancer research.

Factors that Impact Susceptibility to Fiber-Induced Health Effects

J. Testa, J. Below, N. Fukagawa, 2011, Journal of toxicology and environmental health. Part B, Critical reviews.

The pathogenesis of mesothelioma.

J. Testa, R. Kratzke, M. Carbone, 2002, Seminars in oncology.

The promyelocytic leukemia zinc finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival

S. Jhanwar, H. Pass, J. Testa, 2009, Oncogene.

Loss of Methylthioadenosine Phosphorylase and Elevated Ornithine Decarboxylase Is Common in Pancreatic Cancer

J. Testa, H. Cooper, N. Meropol, 2004, Clinical Cancer Research.

Evaluation of techniques for increasing mitotic yield and chromosome length in leukemic cells.

J. Rowley, J. Testa, P. Rapoza, 1984, Acta cytologica.

Detecting MYB and MYBL1 Fusion Genes in Tracheobronchial Adenoid Cystic Carcinoma by Targeted RNA-Sequencing

A. Patchefsky, D. Flieder, J. Testa, 2019, Modern Pathology.

Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions.

J. Testa, Y. Mitsuuchi, B. Balsara, 2004, Carcinogenesis.

Genomic events associated with progression of pleural malignant mesothelioma

R. Lucito, H. Pass, J. Testa, 2009, International journal of cancer.

Universal mapping probes and the origin of human chromosome 3.

K. Buetow, J. Testa, T. Taguchi, 1993, Proceedings of the National Academy of Sciences of the United States of America.

A genetic, physical, and comparative map of rat chromosome 10

K. Buetow, D. Bell, J. Testa, 2009, Mammalian Genome.

BRCA1 Mutational Complementation Induces Synthetic Viability.

G. Gupta, J. Testa, X. Hua, 2020, Molecules and Cells.

Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome

B. Weber, Lin Zhang, P. Gimotty, 2011, Genes, chromosomes & cancer.

Activation of AKT kinases in cancer: implications for therapeutic targeting.

J. Testa, C. Kumar, A. Di Cristofano, 2005, Advances in cancer research.

AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth

Andrew K Godwin, A. Godwin, J. Testa, 2004, Oncogene.

Chromosomes in Lung Cancer

D. Bell, J. Testa, 1997 .

Whole-genome profiling in liposarcomas reveals genetic alterations common to specific telomere maintenance mechanisms.

J. Testa, S. Litwin, M. von Mehren, 2007, Cancer research.

Structure, expression and chromosomal mapping of c-akt: relationship to v-akt and its implications.

J. Testa, T. Franke, A. Bellacosa, 1993, Oncogene.

The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling

J. Testa, Yinfei Tan, Jinfei Xu, 2017, Oncotarget.

Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia

D. Neuberg, A. Look, M. Harris, 2011, The Journal of experimental medicine.

Chromothripsis in a Case of TP53-Deficient Chronic Lymphocytic Leukemia.

S. Jhanwar, J. Testa, J. Pei, 2012, Leukemia research reports.

Advances in the analysis of chromosome alterations in human lung carcinomas.

D. Bell, J. Testa, T. Taguchi, 1997, Cancer genetics and cytogenetics.

Cytogenetic abnormalities in non‐small cell lung carcinoma: Similarity of findings in conventional and feeder cell layer cultures

J. Testa, S. Keller, J. Hunt, 1993, Genes, chromosomes & cancer.

Loss of GATA6 Leads to Nuclear Deformation and Aneuploidy in Ovarian Cancer

A. Godwin, J. Testa, Xiang-Xi Xu, 2009, Molecular and Cellular Biology.

Somatic genetic alterations in human malignant mesothelioma (review).

J. Testa, W. C. Lee, J. R. Testa, 1999, International journal of oncology.

Multiple regions of allelic loss from chromosome arm 6q in malignant mesothelioma.

S. Jhanwar, D. Bell, J. Testa, 1997, Cancer research.

Characterization of unconventional MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice.

N. Copeland, N. Jenkins, C. Morton, 1997, Human molecular genetics.

New markers, D16FC1 and Tp12, differentiate between rat chromosomes 16 and 17.

A. Knudson, J. Testa, P. Tsichlis, 1993, Cytogenetics and cell genetics.

PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth

J. Testa, R. Uzzo, Zongzhi Z. Liu, 2019, Nature Communications.

Inhibition of mesothelioma cancer stem‐like cells with adenovirus‐mediated NK4 gene therapy

Yue Wu, J. Testa, G. Xiao, 2015, International journal of cancer.

Prognostic impact of cytogenetic abnormalities in patients with de novo acute nonlymphocytic leukemia.

Edward J. Lee, J. Testa, C. Schiffer, 1989, Blood.

Cytogenetic studies of a human medullary thyroid carcinoma cell line.

S. Baylin, J. Testa, K. Tanaka, 1987, Cancer genetics and cytogenetics.

Recurrent chromosomal rearrangements implicate oncogenes contributing to T‐cell lymphomagenesis in Lck‐MyrAkt2 transgenic mice

J. Testa, Yinfei Tan, D. Wiest, 2009, Genes, chromosomes & cancer.

Characterization of MOAT-C and MOAT-D, New Members of the MRP/cMOAT Subfamily of Transporter Proteins

J. Testa, L. Bain, G. Kruh, 1999 .

Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.

J. Testa, L. Bain, G. Kruh, 1998, Journal of the National Cancer Institute.

OCI-5/GPC3, a Glypican Encoded by a Gene That Is Mutated in the Simpson-Golabi-Behmel Overgrowth Syndrome, Induces Apoptosis in a Cell Line–specific Manner

J. Testa, L. Penn, J. Filmus, 1998, The Journal of cell biology.

Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22

J. Testa, E. Golemis, I. Serebriiskii, 1997, Oncogene.

Cytogenetics of Malignant Mesothelioma

J. Testa, B. Balsara, S. Apostolou, 2005 .

Comparative genomic hybridization and loss of heterozygosity analyses identify a common region of deletion at 15q11.1-15 in human malignant mesothelioma.

S. Jhanwar, S. Manoir, D. Bell, 1999, Cancer research.

Comparative Genomic Hybridization and Loss of Heterozygosity Analyses Identify a Common Region of Deletion at 15 q 11 . 1 – 15 in Human Malignant Mesothelioma 1

S. Jhanwar, S. Manoir, D. Bell, 1999 .

Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Malignant Mesothelioma

James S. Duncan, J. Testa, Yinfei Tan, 2020, bioRxiv.

High-resolution analysis of 9p loss in human cancer cells using single nucleotide polymorphism-based mapping arrays.

J. Testa, W. Kruger, J. Pei, 2006, Cancer genetics and cytogenetics.

Clinical relevance of chromosome abnormalities in non-small cell lung cancer.

J. Siegfried, J. Testa, S. Litwin, 1998, Cancer genetics and cytogenetics.

Comparative genomic hybridization analysis.

J. Testa, B. Balsara, J. Pei, 2002, Methods in molecular medicine.

Human hepatocellular carcinoma is characterized by a highly consistent pattern of genomic imbalances, including frequent loss of 16q23.1–24.1

K. Buetow, J. Testa, A. De Rienzo, 2001, Genes, chromosomes & cancer.

The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4.

F. Kaye, J. Testa, M. Kelley, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Characterization of 9q;15q whole-arm translocation derivatives in non-small cell lung carcinomas by fluorescence in situ hybridization.

S. Jhanwar, J. Siegfried, J. Testa, 1993, Cancer genetics and cytogenetics.

Techniques for Identifying Cancer Genes

J. Testa, Wen‐Ching Lee, 2000 .

Thymine DNA glycosylase as a novel target for melanoma

M. Einarson, J. Jelinek, Hongmao Sun, 2019, Oncogene.

Involvement of the RAFI locus, at band 3p25, in the 3p deletion of small‐cell lung cancer

H. Brauch, B. Zbar, A. Pfeifer, 1991, Genes, chromosomes & cancer.

Combined chromosome microdissection and comparative genomic hybridization detect multiple sites of amplified DNA in a human lung carcinoma cell line

J. Siegfried, D. Bell, J. Testa, 1997, Genes, chromosomes & cancer.

Correlation of model chromosome number of cultured non-small cell lung carcinomas with DNA index of solid tumor tissue.

J. Siegfried, J. Testa, J. Resau, 1991, Cancer research.

Isochromosome (8q) in four patients with adenocarcinoma of the lung.

J. Testa, J. Resau, I. Miura, 1990, Cancer genetics and cytogenetics.

TNF-α inhibits asbestos-induced cytotoxicity via a NF-κB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis

H. Pass, J. Testa, M. Carbone, 2006, Proceedings of the National Academy of Sciences.

Chromosomal localization of the Ox-44 (CD53) leukocyte antigen gene in man and rodents.

N. Copeland, D. Gilbert, N. Jenkins, 1993, Cytogenetics and cell genetics.

The Vpreb1 and Comt genes are closely linked and sublocalized to rat Chromosome 11q23

D. Bell, J. Testa, R. Yeung, 1996, Mammalian Genome.

A microdissection library of the rat renal carcinoma gene region.

S. Bohlander, D. Bell, J. Testa, 1995, Cytogenetics and cell genetics.

In vitro hypoxia-conditioned colon cancer cell lines derived from HCT116 and HT29 exhibit altered apoptosis susceptibility and a more angiogenic profile in vivo

J. Testa, P. O'dwyer, K. Yao, 2005, British Journal of Cancer.

DLX5 (Distal-less Homeobox 5) Promotes Tumor Cell Proliferation by Transcriptionally Regulating MYC*

J. Testa, Jinfei Xu, 2009, The Journal of Biological Chemistry.

Targeting MYC sensitizes malignant mesothelioma cells to PAK blockage-induced cytotoxicity.

J. Testa, Yinfei Tan, J. Chernoff, 2017, American journal of cancer research.

Detection of DNA gains and losses in primary endometrial carcinomas by comparative genomic hybridization

D. Bell, A. Godwin, J. Testa, 1997, Genes, chromosomes & cancer.

Renal oncocytoma with loss of chromosomes Y and 1 evolving to papillary carcinoma in connection with gain of chromosome 7. Coincidence or progression?

J. Testa, Hong Wu, R. Greenberg, 2005, Cancer genetics and cytogenetics.

Copy neutral loss of heterozygosity in 20q in chronic lymphocytic leukemia/small lymphocytic lymphoma.

M. Millenson, J. Testa, V. Robu, 2014, Cancer genetics.

Cloning and chromosomal localization of a gene encoding a novel serine/threonine kinase belonging to the subfamily of testis-specific kinases.

J. Testa, G. Kopf, P. Visconti, 2001, Genomics.

Comparative genomic hybridization detects frequent overrepresentation of chromosomal material from 3q26, 8q24, and 20q13 in human ovarian carcinomas

A. Godwin, J. Testa, M. Yakushiji, 1997, Genes, chromosomes & cancer.

Association of Lbc Rho Guanine Nucleotide Exchange Factor with α-Catenin-related Protein, α-Catulin/CTNNAL1, Supports Serum Response Factor Activation*

J. Testa, D. Toksoz, K. Merdek, 2002, The Journal of Biological Chemistry.

A novel mechanism of late gene silencing drives SV40 transformation of human mesothelial cells.

J. Testa, M. Carbone, M. Bocchetta, 2008, Cancer research.

Human mesothelial cells are unusually susceptible to simian virus 40-mediated transformation and asbestos cocarcinogenicity.

H. Pass, J. Testa, M. Carbone, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells

J. Testa, P. Poulikakos, F. Kuhajda, 2005, Oncogene.

AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells.

J. Testa, Y. Mitsuuchi, G. Xiao, 2001, Cancer research.

Tumor suppressor genes and the two‐hit model of recessive oncogenesis: Celebrating Alfred Knudson's 80th birthday

J. Testa, O. Hino, 2003, Genes, chromosomes & cancer.

NF2: The wizardry of merlin

Jonathan Chernoff, J. Testa, J. Chernoff, 2003, Genes, chromosomes & cancer.

Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis.

H. Pass, J. Testa, M. Bosenberg, 2009, The American journal of pathology.

Haploinsufficiency in tumor predisposition syndromes: altered genomic transcription in morphologically normal cells heterozygous for VHL or TSC mutation

A. Knudson, W. Linehan, C. Ricketts, 2016, Oncotarget.

The roles of chromatin-remodelers and epigenetic modifiers in kidney cancer.

J. Testa, Haifeng Yang, L. Liao, 2015, Cancer genetics.

NF-κB Inhibition by Bortezomib Permits IFN-γ–Activated RIP1 Kinase–Dependent Necrosis in Renal Cell Carcinoma

J. Testa, M. Cheung, J. Pei, 2013, Molecular Cancer Therapeutics.

NF-kB Inhibition by Bortezomib Permits IFN-g–Activated RIP1 Kinase–Dependent Necrosis in Renal Cell Carcinoma

J. Testa, M. Cheung, J. Pei, 2013 .

Dependent Necrosis in Renal Cell Carcinoma − Kinase Activated RIP 1 − γ B Inhibition by Bortezomib Permits IFN

J. Testa, M. Cheung, J. Pei, 2013 .

NF-k B Inhibition by Bortezomib Permits IFN-g – Activated RIP 1 Kinase – Dependent Necrosis in Renal Cell Carcinoma

J. Testa, M. Cheung, J. Pei, 2013 .

High density DNA array analysis reveals distinct genomic profiles in a subset of gastrointestinal stromal tumors

A. Godwin, J. Testa, B. Eisenberg, 2009, Genes, chromosomes & cancer.

Genome-wide analysis of abdominal and pleural malignant mesothelioma with DNA arrays reveals both common and distinct regions of copy number alteration

A. Borczuk, J. Testa, B. Levy, 2016, Cancer biology & therapy.

The genetics of renal oncocytosis: a possible model for neoplastic progression.

J. Testa, R. Uzzo, P. Cairns, 2004, Cancer genetics and cytogenetics.

Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth

S. Jhanwar, J. Testa, A. Kane, 2005, Oncogene.

An extracellular signal-regulated kinase 2 survival pathway mediates resistance of human mesothelioma cells to asbestos-induced injury.

H. Pass, K. O'Byrne, J. Testa, 2011, American journal of respiratory cell and molecular biology.

Bap1 Is a Bona Fide Tumor Suppressor: Genetic Evidence from Mouse Models Carrying Heterozygous Germline Bap1 Mutations.

J. Testa, Jinfei Xu, Yuwaraj Kadariya, 2016, Cancer research.

Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer.

J. Testa, T. Howard, J. Ohar, 2016, Cancer research.

Germline mutation of Bap1 accelerates development of asbestos-induced malignant mesothelioma.

J. Testa, S. Litwin, Yinfei Tan, 2014, Cancer research.

Eosinophilic differentiation of the human promyelocytic leukemia cell line, HL-60

J. Testa, S. Misawa, G. Gleich, 1984, The Journal of experimental medicine.

The predictive value of initial cytogenetic studies in 148 adults with acute nonlymphocytic leukemia: a 12-year study (1970-1982).

J. Rowley, R. Larson, M. L. Le Beau, 1983, Cancer genetics and cytogenetics.

Chromosome abnormalities in acute leukemia: a higher incidence than previously assumed.

J. Testa, S. Misawa, P. Wiernik, 1983, Cancer genetics and cytogenetics.

Near-tetraploid clones in acute leukemia.

J. Testa, P. Wiernik, N. Oguma, 1983, Blood.

Germline and Somatic Mutations in Human Mesothelioma and Lessons from Asbestos-Exposed Genetically Engineered Mouse Models

J. Testa, M. Cheung, C. Menges, 2017 .

Overall tumor genomic instability: an important predictor of recurrence-free survival in patients with localized clear cell renal cell carcinoma

J. Testa, R. Uzzo, M. Slifker, 2020, Cancer biology & therapy.

Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer

G. Stark, J. Testa, G. Jagannathan, 2018, eLife.

The correlation between gain of chromosome 8q and survival in patients with clear and papillary renal cell carcinoma

J. Testa, R. Uzzo, R. Mehrazin, 2018, Therapeutic advances in urology.

Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma

K. Devarajan, J. Testa, R. Uzzo, 2016, PloS one.

A review of neoplasms with MITF/MiT family translocations.

P. Argani, J. Testa, Shuanzeng Wei, 2022, Histology and histopathology.

A case of acute lymphoblastic leukemia with severe hypodiploidy.

J. Testa, S. Misawa, N. Oguma, 1985, Cancer genetics and cytogenetics.

Vascular Endothelial Growth Factor Is a Promising Therapeutic Target for the Treatment of Clear Cell Carcinoma of the Ovary

R. Burger, J. Testa, M. Ohmichi, 2010, Molecular Cancer Therapeutics.

Correlation of occupation and karyotype in adults with acute nonlymphocytic leukemia

J. Rowley, J. Testa, J. Vardiman, 1982 .

Trisomy 13: A New Recurring Chromosome Abnormality in Acute Leukemia

C. Bloomfield, H. Döhner, J. Testa, 1990 .

Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor.

Roland L. Dunbrack, R L Dunbrack, A. Godwin, 2000, Genomics.

Determination of chromosomal area of double minute chromosomes and a homogeneously staining region in HL-60 human leukemia cells by the use of a color image analyzer

J. Testa, S. Misawa, T. Takamatsu, 1986, Japanese Journal of Human Genetics.

Abnormalities of chromosome 16 in association with acute myelomonocytic leukemia and dysplastic bone marrow eosinophils.

J. Testa, S. Misawa, N. Parsa, 1984, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Unusual cytogenetic findings in two patients with t(4;11) acute leukemia

J. Testa, S. Misawa, R. Leavitt, 1986, International journal of cancer.

Trisomy 13: a new recurring chromosome abnormality in acute leukemia.

C. Bloomfield, H. Döhner, J. Testa, 1990, Blood.

Determination of the specificity of aphidicolin-induced breakage of the human 3p14.2 fragile site.

J. Testa, D. Smith, N. Wang, 1993, Genomics.

p21-activated Kinase Links Rac/Cdc42 Signaling to Merlin*

J. Testa, J. Chernoff, G. Xiao, 2002, The Journal of Biological Chemistry.

Evolution of Karyotypes in Acute Nonlymphocytic Leukemia 1

J. Rowley, J. Testa, J. Vardiman, 2006 .

Application of Chromosome Microarray Analysis for the Differential Diagnosis of Low-grade Renal Cell Carcinoma With Clear Cell and Papillary Features.

J. Testa, R. Uzzo, Shuanzeng Wei, 2020, Applied immunohistochemistry & molecular morphology : AIMM.

Clinical application of RNA sequencing in sarcoma diagnosis

A. Patchefsky, D. Flieder, J. Testa, 2019, Medicine.

Dysmyelopoietic syndrome: sequential clinical and cytogenetic studies.

J. Rowley, J. Testa, J. Vardiman, 1980, Blood.

Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide

Ivana K. Kim, S. Puig, N. Hayward, 2018, Journal of the National Cancer Institute.

Human Follicle-Stimulating Hormone (FSH) Receptor Interacts with the Adaptor Protein APPL1 in HEK 293 Cells: Potential Involvement of the PI3K Pathway in FSH Signaling1

J. Testa, P. Poulikakos, J. Dias, 2004, Biology of reproduction.

Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter.

D. Bell, J. Testa, G. Kruh, 1998, Cancer research.

Connecting molecular pathways to hereditary cancer risk syndromes.

J. Testa, J. Schiffman, D. Malkin, 2013, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.

Analysis of the Interaction of the Novel RNA Polymerase II (pol II) Subunit hsRPB4 with Its Partner hsRPB7 and with pol II

Erica A. Golemis, Vladimir Khazak, J. Testa, 1998, Molecular and Cellular Biology.

A Phosphotyrosine Proteomic Screen Identifies Multiple Tyrosine Kinase Signaling Pathways Aberrantly Activated in Malignant Mesothelioma.

J. Testa, J. Chernoff, B. Mossman, 2010, Genes & cancer.

Cancer stem‐like cell properties are regulated by EGFR/AKT/β–catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma

Ying Liu, Gong Zhang, Kai-Tai Yao, 2013, The FEBS journal.

induction of the stemness factor, Lin28B Inactivation of ribosomal protein L22 promotes transformation by

J. Testa, Rugang Zhang, S. Hunger, 2012 .

CD45-deficient severe combined immunodeficiency caused by uniparental disomy

Roland L. Dunbrack, J. Testa, X. Zhong, 2012, Proceedings of the National Academy of Sciences.

Genomic imbalances in peripheral blood confirm the diagnosis of myelodysplastic syndrome in a patient presenting with non-immune hemolytic anemia

J. Testa, E. Dulaimi, J. Pei, 2016, Leukemia research reports.

RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance

J. Testa, J. Hoffmann, D. Wiest, 2019, PloS one.

Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily.

J. Testa, G. Kruh, M. Belinsky, 2001, Cancer letters.

T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation.

L. Zon, R. White, D. Neuberg, 2010, Cancer cell.

Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary

J. Testa, S. Mabuchi, Kae Hashimoto, 2014, Molecular Cancer Research.

The biology of ovarian cancer development

A. Godwin, J. Testa, T. Hamilton, 2010, Cancer.

Clinical application of RNA sequencing in sarcoma diagnosis

A. Patchefsky, D. Flieder, J. Testa, 2019, Medicine.

Preclinical Models of Malignant Mesothelioma

A. Berns, J. Testa, 2020, Frontiers in Oncology.

Activated TNF-α/NF-κB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice

J. Testa, A. Kane, M. Carbone, 2009, Proceedings of the National Academy of Sciences.

A mouse model recapitulating molecular features of human mesothelioma.

S. Jhanwar, K. Devarajan, J. Testa, 2005, Cancer research.

Cells cultured from non-small cell lung carcinomas are representative of solid tumor tissue based on cytogenetic evidence

J. Siegfried, J. Testa, J. Resau, 1991 .

RAD001 Inhibits Human Ovarian Cancer Cell Proliferation, Enhances Cisplatin-Induced Apoptosis, and Prolongs Survival in an Ovarian Cancer Model

R. Ozols, J. Testa, S. Mabuchi, 2007, Clinical Cancer Research.

Application of Chromosome Microarray Analysis for the Differential Diagnosis of Low-grade Renal Cell Carcinoma With Clear Cell and Papillary Features.

J. Testa, R. Uzzo, Shuanzeng Wei, 2020 .

Inflammation as a chemoprevention target in asbestos-induced malignant mesothelioma.

N. Neamati, J. Testa, M. S. Miller, 2022, Carcinogenesis.

Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase

J. Testa, X. Graña, Yinfei Tan, 2020, Prostate cancer and prostatic diseases.

Detection of clonal karyotypic abnormalities in most patients with acute nonlymphocytic leukemia examined using short-term culture techniques.

J. Testa, S. Misawa, D. Hogge, 1986, Cancer genetics and cytogenetics.

Monosomy of Chromosome 9 Is Associated With Higher Grade, Advanced Stage, and Adverse Outcome in Clear-cell Renal Cell Carcinoma.

J. Testa, R. Uzzo, Shuanzeng Wei, 2020, Clinical genitourinary cancer.

Bap 1 Is a Bona Fide Tumor Suppressor : Genetic Evidence from Mouse Models Carrying Heterozygous Germline Bap 1 Mutations

J. Testa, Jinfei Xu, Yuwaraj Kadariya, 2016 .

Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors

D. Flieder, A. Godwin, J. Testa, 2008, Proceedings of the National Academy of Sciences.

Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma

Karthik Devarajan, Stephen C. Peiper, Wei Jiang, 2017, Oncotarget.

The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability

L. Aaltonen, A. Godwin, J. Testa, 1999, Nature Genetics.

Preclinical Ef fi cacy for AKT Targeting in Clear Cell Carcinoma of the Ovary

J. Testa, S. Mabuchi, Kae Hashimoto, 2015 .

mTOR Is a Promising Therapeutic Target Both in Cisplatin-Sensitive and Cisplatin-Resistant Clear Cell Carcinoma of the Ovary

J. Testa, M. Ohmichi, M. Hayashi, 2009, Clinical Cancer Research.

Cancer Therapy : Preclinical mTOR Is a Promising Therapeutic Target Both in Cisplatin-Sensitive and Cisplatin-Resistant Clear Cell Carcinoma of the Ovary

J. Testa, M. Ohmichi, M. Hayashi, 2009 .

"Microgranular" acute promyelocytic leukemia: a distinct clinical, ultrastructural, and cytogenetic entity.

J. Rowley, J. Testa, A. Butler, 1980, Blood.

Minimally differentiated acute nonlymphocytic leukemia: a distinct entity.

J. Testa, C. Schiffer, E. Lee, 1987, Blood.

Isolation of highly multidrug-resistant P388 cells from drug-sensitive P388/S cells by flow cytometric cell sorting.

J. Testa, J. Ordonez, D. Ross, 1988, Cytometry.

Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14.

J. Testa, S. Dower, T. Taguchi, 1996, Genomics.

Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation.

J. Testa, D. Toksoz, K. Merdek, 2002, The Journal of biological chemistry.

Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship

Andrea I. McClatchey, J. Testa, Qunli Xu, 2014, Science Translational Medicine.

51 Platinum sensitivity in mesothelioma cell lines: Relationship to cellular glutathione level

J. Testa, S. Johnson, P. Calvert, 1997 .

Molecular Cloning of the cDNA and Chromosome Localization of the Gene for Human Ubiquitin-conjugating Enzyme 9*

J. Testa, D. Callen, T. Shenk, 1996, The Journal of Biological Chemistry.

Association of the translocation (15;17) with malignant proliferation of promyelocytes in acute leukemia and chronic myelogenous leukemia at blastic crisis.

J. Testa, S. Misawa, C. Schiffer, 1986, Blood.

Cytogenetic patterns in acute nonlymphocytic leukemia

J. Rowley, J. Testa, 1978, Virchows Archiv. B, Cell pathology.

Chromosome translocations in human cancer.

J. Testa, 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Chromosomal banding patterns in patients with acute nonlymphocytic leukemia

J. Rowley, J. Testa, 1980 .

Hypergranular promyelocytic leukemia (APL): cytogenetic and ultrastructural specificity.

J. Rowley, J. Testa, J. Vardiman, 1978, Blood.

Cytogenetic and ultrastructural features of de novo acute promyelocytic leukemia; The university of Chicago experience (1973–1978)☆

J. Rowley, J. Testa, A. Butler, 1979 .

Molecular Cytogenetic Analysis of the Scleractinian Coral Acropora solitaryensis Veron & Wallace 1984

J. Testa, A. Tominaga, T. Taguchi, 2014, Zoological science.

Growth inhibition and induction of apoptosis in mesothelioma cells by selenium and dependence on selenoprotein SEP15 genotype

S. Jhanwar, J. Testa, Y. Mitsuuchi, 2004, Oncogene.

Mapping of guanylin to murine chromosome 4 and human chromosome 1p34-p35.

N. Copeland, D. Gilbert, N. Jenkins, 1995, Genomics.

APPL1 Associates with TrkA and GIPC1 and Is Required for Nerve Growth Factor-Mediated Signal Transduction

Mark L. Grimes, David R. Kaplan, Celia Quevedo, 2006, Molecular and Cellular Biology.

Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2

Erica A Golemis, Satoshi Tanno, Steven W. Johnson, 1999, Oncogene.

Constitutively Active Akt1 Cooperates with KRasG12D to Accelerate In Vivo Pancreatic Tumor Onset and Progression☆☆☆

J. Testa, Andres J Klein-Szanto, D. Altomare, 2015, Neoplasia.

The retinoblastoma-related gene, RB2, maps to human chromosome 16q12 and rat chromosome 19.

K. Klinga-Levan, A. Knudson, D. Bell, 1993, Oncogene.

Inactivation of Tp53 and Pten drives rapid development of pleural and peritoneal malignant mesotheliomas

J. Testa, Jinfei Xu, Yuwaraj Kadariya, 2018, Journal of cellular physiology.

Localization of human NQO1 gene to chromosome 16q22 and NQO2-6p25 and associated polymorphisms.

D. Bell, J. Testa, A. Jaiswal, 1999, Pharmacogenetics.

Identification of ArgBP1, an Arg protein tyrosine kinase binding protein that is the human homologue of a CNS-specific Xenopus gene.

D. Krainc, J. Testa, E. Golemis, 1996, Oncogene.

SV40 and human brain tumors

A. Gazdar, H. Pass, J. Testa, 1997, International journal of cancer.

Variation amongst K562 cell cultures.

J. Testa, D. Ross, I. Dimery, 1983, Experimental hematology.

Increased fatty acid synthase is a therapeutic target in mesothelioma.

E. Gabrielson, J. Testa, F. Kuhajda, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Protein Kinase C Phosphorylation Disrupts Na+/H+ Exchanger Regulatory Factor 1 Autoinhibition and Promotes Cystic Fibrosis Transmembrane Conductance Regulator Macromolecular Assembly*

J. Testa, P. Poulikakos, Poulikos I. Poulikakos, 2007, Journal of Biological Chemistry.

Response to 5‐azacytidine in patients with refractory acute nonlymphocytic leukemia and association with chromosome findings

J. Rowley, R. Larson, J. Testa, 1982, Cancer.

Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis

R. M. Simpson, J. Testa, W. Dubois, 2020, Molecular Cancer Therapeutics.

Combined classical cytogenetics and microarray‐based genomic copy number analysis reveal frequent 3;5 rearrangements in clear cell renal cell carcinoma

J. Testa, G. Hudes, Angen Liu, 2010, Genes, chromosomes & cancer.

Identification of Akt Interaction Protein PHF20/TZP That Transcriptionally Regulates p53*

J. Cheng, J. Testa, Donghwa Kim, 2012, The Journal of Biological Chemistry.

Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin

Arti Shukla, H. Pass, J. Testa, 2010, Molecular Cancer.

Group I p21-Activated Kinases (PAKs) Promote Tumor Cell Proliferation and Survival through the AKT1 and Raf–MAPK Pathways

J. R. Peterson, J. Testa, Jinfei Xu, 2012, Molecular Cancer Research.

ArgBP2γ interacts with Akt and p21-activated kinase-1 and promotes cell survival.

Satoshi Kaneko, S. Nicosia, J. Cheng, 2016, The Journal of Biological Chemistry.

Clinical and cytogenetic correlations of abnormal megakaryocytopoiesis in patients with acute leukemia and chronic myelogenous leukemia in blast crisis.

J. Testa, C. Schiffer, E. Lee, 1990, Leukemia.

Localization of a candidate colon tumor-suppressor gene (DRA) to 7q22-q31.1 by fluorescence in situ hybridization.

J. Testa, T. Taguchi, T. Papas, 1994, Genomics.

Philadelphia chromosome‐positive acute leukemia: Morphologic and clinical correlations

J. Testa, C. Schiffer, G. Helenglass, 1987, American journal of hematology.

Metanephric adenofibroma: robotic partial nephrectomy of a large Wilms' tumor variant.

J. Testa, R. Uzzo, A. Kutikov, 2010, The Canadian journal of urology.

SWOG 0722: A phase II study of mTOR inhibitor everolimus (RAD001) in malignant pleural mesothelioma (MPM).

S. Ou, A. Wozniak, D. Gandara, 2012 .

Novel human and mouse annexin A10 are linked to the genome duplications during early chordate evolution.

N. Copeland, D. Gilbert, N. Jenkins, 1999, Genomics.

The human GATA-6 gene: structure, chromosomal location, and regulation of expression by tissue-specific and mitogen-responsive signals.

K Walsh, Jason A. Lowry, D. Bell, 1996, Genomics.

Isolated BAP1 Genomic Alteration in Malignant Pleural Mesothelioma Predicts Distinct Immunogenicity with Implications for Immunotherapeutic Response

M. Becich, J. Testa, H. Osmanbeyoglu, 2022, Cancers.

Molecular Medicine in Practice Molecular Cancer Therapeutics Vascular Endothelial Growth Factor Is a Promising Therapeutic Target for the Treatment of Clear Cell Carcinoma of the Ovary

R. Burger, J. Testa, M. Ohmichi, 2010 .

Chromosome 16 rearrangements in acute myelomonocytic leukemia with abnormal eosinophils.

J. Testa, S. Misawa, D. Hogge, 1984, The New England journal of medicine.

A variant 8;21 translocation in acute myeloblastic leukemia

J. Testa, S. Misawa, N. Oguma, 1983, American journal of hematology.

The human tyrosine kinase gene (FER) maps to chromosome 5 and is deleted in myeloid leukemias with a del(5q).

N. Heisterkamp, J. Groffen, J. Testa, 1990, Cytogenetics and cell genetics.

Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models.

J. Testa, Yinfei Tan, M. Slifker, 2019, Cancer research.

Acquired chromosome rearrangements, including fine interstitial deletions, in a patient with Down syndrome and monoblastic leukemia.

J. Testa, S. Misawa, R. Leavitt, 1984, Pediatrics.

BAP1 (BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase))

J. Testa, A. Rienzo, 2018, Atlas of Genetics and Cytogenetics in Oncology and Haematology.

APPL 1 Associates with TrkA and GIPC 1 and Is Required for Nerve Growth Factor-Mediated Signal Transduction

J. Testa, D. Kaplan, F. Miller, 2006 .

Insulin-like growth factor 1 receptor (IGF-1R): A potential therapeutic target for gastrointestinal stromal tumors (GIST)

D. Flieder, A. Godwin, J. Testa, 2008 .

Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas

J. Cheng, J. Testa, B. Ruggeri, 1998, Molecular carcinogenesis.

Identification of zinc finger mRNAs using domain-specific differential display.

R. Ozols, J. Testa, N. A. Lissy, 1996, Analytical biochemistry.

Cytogenetic abnormalities in non‐small cell lung carcinoma: Similarity of findings in conventional and feeder cell layer cultures

J. Siegfried, J. Testa, S. Keller, 1993, Genes, chromosomes & cancer.

Chromosome alterations in 21 non‐small cell lung carcinomas

J. Siegfried, J. Testa, J. Resau, 1990, Genes, chromosomes & cancer.

Karyotypic patterns and their clinical significance in polycythemia vera

J. Rowley, J. Testa, J. Vardiman, 1981, American journal of hematology.

The phosphatidylinositol 3-kinase/AKT signal transduction pathway plays a critical role in the expression of p21WAF1/CIP1/SDI1 induced by cisplatin and paclitaxel.

Stephen J. Williams, J. Testa, M. Selvakumaran, 2000, Cancer research.

Isochromosome 7p, i(7)(p10): A rare AML, myelodysplasia-related entity

J. Testa, R. Nejati, J. Pei, 2023, Leukemia research reports.

Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21.

U. Francke, N. Copeland, N. Jenkins, 1995, Cytogenetics and cell genetics.

Correlation of chromosome (Chr) 14 loss and 5q gain with outcomes of pazopanib treatment in patients (pts) with metastatic clear cell renal cell carcinoma (mRCC).

J. Testa, G. Hudes, J. Pei, 2012 .

Cytogenetic analysis of bone marrow and peripheral blood samples stored in fixative for several years.

J. Rowley, J. Testa, M. Waghray, 1981, Stain technology.

Involvement of the RAFI locus, at band 3p25, in the 3p deletion of small‐cell lung cancer

H. Brauch, B. Zbar, A. Pfeifer, 1991, Genes, chromosomes & cancer.

Genome Scanning Detects Amplification of the Cathepsin B Gene (CtsB) in Transformed Rat Ovarian Surface Epithelial Cells

A. Godwin, J. Testa, T. Taguchi, 1999, The Journal of the Society for Gynecologic Investigation: JSGI.

Prognostic significance of posttransfusion hepatitis and chromosomal abnormalities in adult acute nonlymphocytic leukemia.

J. Rowley, J. Testa, A. Baker, 1982, Cancer genetics and cytogenetics.

Genomic events associated with progression of pleural malignant mesothelioma

R. Lucito, H. Pass, J. Testa, 2009, International journal of cancer.

Appl1 Is Dispensable for Mouse Development, and Loss of Appl1 Has Growth Factor-selective Effects on Akt Signaling in Murine Embryonic Fibroblasts*

J. Testa, Yinfei Tan, Chao Wu, 2009, The Journal of Biological Chemistry.

OCI-5/GPC3, a Glypican Encoded by a Gene That Is Mutated in the Simpson-Golabi-Behmel Overgrowth Syndrome, Induces Apoptosis in a Cell Line–specific Manner

J. Testa, L. Penn, J. Filmus, 1998, The Journal of cell biology.

Centromere spreading in acute nonlymphocytic leukemia.

J. Testa, S. Misawa, J. Gallo, 1984, Cancer genetics and cytogenetics.

Variable differentiative response of 6-thioguanine-resistant HL60 sublines: possible relationship to double-minute chromosomes.

J. Testa, R. Gallagher, A. Ferrari, 1983, Progress in nucleic acid research and molecular biology.

Cloning and localization of a human diphthamide biosynthesis-like protein-2 gene, DPH2L2.

A. Godwin, J. Testa, D. C. Schultz, 1998, Genomics.

Protein Kinase C Phosphorylation Disrupts Na/H Exchanger Regulatory Factor 1 Autoinhibition and Promotes Cystic Fibrosis Transmembrane Conductance Regulator

J. Testa, Poulikos I. Poulikakos, Z. Bu, 2007 .

Localization of three novel hybrid breakpoints and refinement of 18 marker assignments in the human 3cen-p21.1 region.

J. Testa, N. Wang, D. Smith, 1992, Genomics.