P. Fossa

发表

Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at adrenergic α₁- and serotonine 5-HT1A receptors.

A. Prandi, S. Franchini, Leda Ivanova Manasieva, 2012, Journal of medicinal chemistry.

New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment.

L. Milanesi, E. Fedele, P. Fossa, 2016, European journal of medicinal chemistry.

Synthesis, biological evaluation, and molecular modeling of new 3-(cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) Oxime (GEBR-7b) related phosphodiesterase 4D (PDE4D) inhibitors.

E. Fedele, P. Fossa, C. Brullo, 2014, Journal of medicinal chemistry.

Chemometric Study and Validation Strategies in the Structure-Activity Relationships of New Cardiotonic Agents

Michele Forina, Paola Fossa, Luisa Mosti, 1997 .

Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives.

A. Prandi, S. Franchini, P. Fossa, 2016, European journal of medicinal chemistry.

Fluorometric detection of protein‐ligand engagement: The case of phosphodiesterase5

M. Giorgi, S. Franchini, P. Fossa, 2018, Journal of pharmaceutical and biomedical analysis.

Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure-activity relationship studies on O-[2-(hetero)arylethyl]-N-phenylthiocarbamates.

P. Fossa, R. Loddo, G. Sanna, 2008, Bioorganic & medicinal chemistry.

Novel angular furo and thieno-quinolinones: synthesis and preliminary photobiological studies.

P. Fossa, C. Marzano, L. Mosti, 2002, Bioorganic & medicinal chemistry.

Activity of 3-carbethoxyangelicin photolysis products.

P. Fossa, C. Marzano, S. Caffieri, 1997, Journal of photochemistry and photobiology. B, Biology.

Ligand-based homology modelling of the human CB2 receptor SR144528 antagonist binding site: a computational approach to explore the 1,5-diaryl pyrazole scaffold

P. Fossa, E. Cichero, Sara Guariento, 2015 .

New Insights into the Binding Features of F508del CFTR Potentiators: A Molecular Docking, Pharmacophore Mapping and QSAR Analysis Approach

M. Casale, P. Fossa, E. Cichero, 2020, Pharmaceuticals.

Exploring the QSAR of Pyrazolo[3,4‐b]Pyridine, Pyrazolo[3,4‐b]Pyridone and Pyrazolo[3,4‐b]Pyrimidine Derivatives as Antagonists for A1 Adenosine Receptor

Chiara Casolino, Paola Fossa, Elena Cichero, 2009 .

Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors.

M. Trincavelli, C. Martini, P. Fossa, 2005, Journal of medicinal chemistry.

Ionization behaviour and tautomerism-dependent lipophilicity of pyridine-2(1H)-one cardiotonic agents.

P. Fossa, A. Carotti, L. Mosti, 2000, Bioorganic & medicinal chemistry.

Identification of a high affinity binding site for abscisic acid on human lanthionine synthetase component C-like protein 2.

P. Fossa, E. Cichero, L. Sturla, 2018, The international journal of biochemistry & cell biology.

Affinity prediction on A1 adenosine receptor agonists: the chemometric approach.

M. Forina, P. Fossa, S. Schenone, 2006, Bioorganic & medicinal chemistry.

Quinolinedione nucleus as a novel scaffold for A1 and A2A adenosine receptor antagonists

P. Fossa, M. Floreani, L. Mosti, 2008, Medicinal Chemistry Research.

Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of A1-adenosine receptor (A1AR) ligands.

C. Martini, P. Fossa, S. Schenone, 2001, Bioorganic & medicinal chemistry letters.

New arylsparteine derivatives as positive inotropic drugs

P. Fossa, E. Cichero, F. Novelli, 2017, Journal of enzyme inhibition and medicinal chemistry.

Impaired Chaperone Activity of Human Heat Shock Protein Hsp27 Site-Specifically Modified with Argpyrimidine.

P. Fossa, E. Cichero, C. Becker, 2016, Angewandte Chemie.

A new milrinone analog: role of binding to A1 adenosine receptor in its positive inotropic effect on isolated guinea pig and rat atria.

P. Fossa, S. Gessi, P. Borea, 1997, The Journal of pharmacology and experimental therapeutics.

Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1

A. Chiò, P. Fossa, E. Cichero, 2016, Human mutation.

Clinical features and molecular modelling of novel MPZ mutations in demyelinating and axonal neuropathies

P. Fossa, A. Geroldi, E. Bellone, 2009, European Journal of Human Genetics.

Further Insights in the Binding Mode of Selective Inhibitors to Human PDE4D Enzyme Combining Docking and Molecular Dynamics

L. Milanesi, P. Fossa, E. Cichero, 2016, Molecular informatics.

Matrine modulates HSC70 levels and rescues ΔF508‐CFTR

P. Fossa, M. Turco, M. Mazzei, 2012, Journal of cellular physiology.

Synthesis, molecular modeling and SAR study of novel pyrazolo[5,1-f][1,6]naphthyridines as CB2 receptor antagonists/inverse agonists.

P. Fossa, E. Cichero, S. Merighi, 2016, Bioorganic & medicinal chemistry.

New milrinone analogues: in vitro study of structure-activity relationships for positive inotropic effect, antagonism towards endogenous adenosine, and inhibition of cardiac type III phosphodiesterase

P. Fossa, S. Gessi, P. Borea, 2003, Naunyn-Schmiedeberg's Archives of Pharmacology.

Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing

P. Fossa, N. Pedemonte, M. Rusnati, 2022, International journal of molecular sciences.

A complex phenotype in a child with familial HDL deficiency due to a novel frameshift mutation in APOA1 gene (apoA-IGuastalla).

P. Fossa, R. Fresa, E. Favari, 2015, Journal of clinical lipidology.

Hit-to-Lead Optimization of Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists with a Diphenylmethane-Scaffold: Design, Synthesis, and Biological Study.

R. Gainetdinov, P. Fossa, E. Cichero, 2016, Journal of medicinal chemistry.

Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists.

R. Gainetdinov, P. Fossa, E. Cichero, 2015, Journal of medicinal chemistry.

Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties.

M. García-Arencibia, P. Fossa, E. Cichero, 2016, European journal of medicinal chemistry.

Homology Modeling, Docking Studies and Molecular Dynamic Simulations Using Graphical Processing Unit Architecture to Probe the Type‐11 Phosphodiesterase Catalytic Site: A Computational Approach for the Rational Design of Selective Inhibitors

L. Milanesi, P. Fossa, E. Cichero, 2013, Chemical biology & drug design.

ω‐Dialkylaminoalkyl ethers of phenyl‐(5‐substituted 1‐phenyl‐1H‐pyrazol‐4‐yl)methanols with analgesic and anti‐inflammatory activity

P. Fossa, M. Ghia, F. Mattioli, 1997 .

Fast course ALS presenting with vocal cord paralysis: Clinical features, bioinformatic and modelling analysis of the novel SOD1 Gly147Ser mutation

P. Fossa, E. Cichero, A. Geroldi, 2012, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

Synthesis and pharmacological characterization of functionalized 2-pyridones structurally related to the cardiotonic agent milrinone.

P. Fossa, M. Floreani, L. Mosti, 2003, Bioorganic & medicinal chemistry.

Inotropic agents. Synthesis and structure-activity relationships of new milrinone related cAMP PDE III inhibitors.

R. Boggia, P. Fossa, M. Floreani, 1997, Farmaco.

Insights into structure-activity relationships from lipophilicity profiles of pyridin-2(1H)-one analogs of the cardiotonic agent milrinone.

P. Fossa, M. de Candia, A. Carotti, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Toward the identification of the cardiac cGMP inhibited-phosphodiesterase catalytic site

Paola Fossa, Luisa Mosti, Raffaella Boggia, 1998, J. Comput. Aided Mol. Des..

α1‐Adrenoceptor Antagonists. Rational Design, Synthesis and Biological Evaluation of New Trazodone‐Like Compounds.

P. Fossa, M. Botta, G. Giannaccini, 2002 .

Synthesis of new 5,6-dihydrobenzo[h]quinazoline 2,4-diamino substituted and antiplatelet/antiphlogistic activities evaluation.

P. Fossa, E. Cichero, C. Brullo, 2012, Bioorganic & medicinal chemistry letters.

4‐Substituted 1,5‐Diarylpyrazole, Analogues of Celecoxib: Synthesis and Preliminary Evaluation of Biological Properties.

P. Fossa, F. Mattioli, L. Mosti, 2004 .

Further Insights Into the Pharmacology of the Human Trace Amine‐Associated Receptors: Discovery of Novel Ligands for TAAR1 by a Virtual Screening Approach

R. Gainetdinov, S. Franchini, P. Fossa, 2014, Chemical biology & drug design.

alpha(1)-Adrenoceptor antagonists. Rational design, synthesis and biological evaluation of new trazodone-like compounds.

P. Fossa, M. Botta, G. Giannaccini, 2002, Bioorganic & medicinal chemistry letters.

Autoxidation Products of the Methanolic Extract of the Leaves of Combretum micranthum Exert Antiviral Activity against Tomato Brown Rugose Fruit Virus (ToBRFV)

P. Fossa, A. Bisio, V. Iobbi, 2022, Molecules.

Synthesis and in vitro antiplatelet activity of new 4-(1-piperazinyl)coumarin derivatives. Human platelet phosphodiesterase 3 inhibitory properties of the two most effective compounds described and molecular modeling study on their interactions with phosphodiesterase 3A catalytic site.

P. Fossa, G. Leoncini, L. Mosti, 2007, Journal of medicinal chemistry.

Docking-based 3D-QSAR analyses of pyrazole derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors

P. Fossa, E. Cichero, 2012, Journal of Molecular Modeling.

Rational design, synthesis and biological evaluation of new 1,5-diarylpyrazole derivatives as CB1 receptor antagonists, structurally related to rimonabant.

P. Fossa, E. Cichero, L. Mosti, 2008, European journal of medicinal chemistry.

New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation.

P. Fossa, C. Brullo, S. Schenone, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and cardiotonic activity of novel pyrimidine derivatives: crystallographic and quantum chemical studies.

P. Fossa, G. Santostasi, M. Floreani, 1996, Journal of medicinal chemistry.

Synthesis, in vitro antiplatelet activity and molecular modelling studies of 10-substituted 2-(1-piperazinyl)pyrimido[1,2-a]benzimidazol-4(10H)-ones.

G. Damonte, P. Fossa, E. Cichero, 2013, European journal of medicinal chemistry.

Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.

M. Modugno, P. Fossa, C. Tintori, 2006, Journal of medicinal chemistry.

Docking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors

P. Fossa, E. Cichero, O. Bruno, 2012, Journal of enzyme inhibition and medicinal chemistry.

Reaction of 2‐dimethylaminomethylene‐1,3‐diones with dinucleophiles. X. synthesis of 5‐substituted ethyl or methyl 4‐isoxazolecarboxylates and methyl 4‐(2,2‐dimethyl‐1‐oxopropyl)‐5‐isoxazolecarboxylate

P. Schenone, P. Fossa, G. Menozzi, 1991 .

4-substituted 1-methyl-1H-indazoles with analgesic, antiinflammatory and antipyretic activities.

P. Schenone, P. Fossa, L. Mosti, 1992, Farmaco.

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.

Annalisa Salis, Gianluca Damonte, Paola Fossa, 2015, European journal of medicinal chemistry.

Synthesis of N-substituted-N-acylthioureas of 4-substituted piperazines endowed with local anaesthetic, antihyperlipidemic, antiproliferative activities and antiarrythmic, analgesic, antiaggregating actions.

P. Fossa, S. Schenone, W. Filippelli, 2003, Farmaco.

Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line.

P. Fossa, S. Schenone, M. Botta, 2004, European journal of medicinal chemistry.

Labdane Diterpenoids from Salvia tingitana Etl. Synergize with Clindamycin against Methicillin-Resistant Staphylococcus aureus

P. Fossa, P. Brun, A. Bisio, 2021, Molecules.

In silico evaluation of human small heat shock protein HSP27: homology modeling, mutation analyses and docking studies.

P. Fossa, E. Cichero, 2015, Bioorganic & medicinal chemistry.

1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors.

Silvia Franchini, Paola Fossa, Elena Cichero, 2010, European journal of medicinal chemistry.

Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists.

C. Martini, P. Fossa, S. Schenone, 2002, Journal of medicinal chemistry.

In silico rationalization of the structural and physicochemical requirements for photobiological activity in angelicine derivatives and their heteroanalogues

Fabrizio Giordanetto, Paola Fossa, Giulia Menozzi, 2003, J. Comput. Aided Mol. Des..

New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking.

P. Fossa, E. Cichero, J. Fernández-Ruiz, 2017, European journal of medicinal chemistry.

Structure–Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma

S. Franchini, P. Fossa, E. Cichero, 2017, ChemMedChem.

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7

G. Rastelli, P. Fossa, A. Mangoni, 2020, Molecules.

HSPB1 and HSPB8 in inherited neuropathies: study of an Italian cohort of dHMN and CMT2 patients

P. Fossa, A. Geroldi, E. Bellone, 2011, Journal of the peripheral nervous system : JPNS.

CoMFA and CoMSIA analyses on 4-oxo-1,4-dihydroquinoline and 4-oxo-1,4-dihydro-1,5-, -1,6- and -1,8-naphthyridine derivatives as selective CB2 receptor agonists

P. Fossa, E. Cichero, L. Mosti, 2010, Journal of molecular modeling.

A novel mutation in the N-terminal acting-binding domain of Filamin C protein causing a distal myofibrillar myopathy

P. Fossa, A. Geroldi, A. Schenone, 2019, Journal of the Neurological Sciences.

Recent Strategic Advances in CFTR Drug Discovery: An Overview

Alessandro Orro, Pasqualina D'Ursi, Paola Fossa, 2020, International journal of molecular sciences.

In silico drug repositioning on F508del-CFTR: A proof-of-concept study on the AIFA library.

P. Fossa, E. Cichero, N. Pedemonte, 2021, European journal of medicinal chemistry.

Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.

Silvia Schenone, Alessandra Pani, Paola Fossa, 2005, Journal of medicinal chemistry.

Novel pyrrolocycloalkylpyrazole analogues as CB1 ligands

P. Fossa, E. Cichero, P. Lazzari, 2018, Chemical biology & drug design.

Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor.

Luciano Milanesi, Anna Marabotti, Pasqualina D'Ursi, 2011, European journal of medicinal chemistry.

New insights into PDE4B inhibitor selectivity: CoMFA analyses and molecular docking studies

P. Fossa, E. Cichero, Sara Guariento, 2016, Molecular Diversity.

Synthesis, biological evaluation and molecular modelling studies on benzothiadiazine derivatives as PDE4 selective inhibitors.

P. Fossa, A. Hatzelmann, L. Mosti, 2005, Bioorganic & medicinal chemistry.

Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation.

C. Martini, P. Fossa, S. Schenone, 2004, European journal of medicinal chemistry.

CoMFA and CoMSIA analyses on 1,2,3,4-tetrahydropyrrolo[3,4-b]indole and benzimidazole derivatives as selective CB2 receptor agonists

P. Fossa, E. Cichero, L. Mosti, 2010, Journal of molecular modeling.

Insights into the Structure and Pharmacology of the Human Trace Amine‐Associated Receptor 1 (hTAAR1): Homology Modelling and Docking Studies

R. Gainetdinov, P. Fossa, E. Cichero, 2013, Chemical biology & drug design.

Modelling the interaction of steroid receptors with endocrine disrupting chemicals

Luciano Milanesi, Erika Salvi, Pasqualina D'Ursi, 2005, BMC Bioinformatics.

4-substituted 1,5-diarylpyrazole, analogues of celecoxib: synthesis and preliminary evaluation of biological properties.

P. Fossa, F. Mattioli, L. Mosti, 2003, Farmaco.

Acylthiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking studies and ligand-based CoMFA and CoMSIA analyses

P. Fossa, E. Cichero, L. Mosti, 2009, Journal of molecular modeling.

Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.

Annalisa Salis, Gianluca Damonte, Paola Fossa, 2018, European journal of medicinal chemistry.

Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT1A receptor agonists for CNS disorders and neuropathic pain.

S. Franchini, P. Fossa, E. Cichero, 2018, Future medicinal chemistry.

Early onset demyelinating Charcot‐Marie‐Tooth disease caused by a novel in‐frame isoleucine deletion in peripheral myelin protein 2

P. Lanteri, P. Fossa, A. Geroldi, 2020, Journal of the peripheral nervous system : JPNS.

Discovery of a new series of 5-HT1A receptor agonists.

Silvia Franchini, Paola Fossa, A. Prandi, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and Preliminary Biological Evaluation of Novel N-Substituted 1-Amino-3-[1-methyl(phenyl)-1H-indazol-4-yloxy]-propan-2-ols Interesting as Potential Antiarrhythmic, Local Anaesthetic and Analgesic Agents

P. Fossa, W. Filippelli, S. Gessi, 2000, Arzneimittelforschung.

Identification of a Potent and Selective 5-HT1A Receptor Agonist with In Vitro and In Vivo Antinociceptive Activity

S. Franchini, P. Fossa, E. Cichero, 2020, ACS chemical neuroscience.

Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation

P. Fossa, E. Cichero, D. Pareyson, 2020, Cells.

Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors.

A. Prandi, S. Franchini, P. Fossa, 2014, European journal of medicinal chemistry.

Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists.

S. Franchini, Leda Ivanova Manasieva, P. Fossa, 2017, European journal of medicinal chemistry.

T137A variant is a pathogenetic SOD1 mutation associated with a slowly progressive ALS phenotype

P. Fossa, E. Cichero, E. Bellone, 2012, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

Probing In Silico the Benzimidazole Privileged Scaffold for the Development of Drug-like Anti-RSV Agents

P. Fossa, E. Cichero, S. Schenone, 2021, Pharmaceuticals.

An Update on CFTR Drug Discovery: Opportunities and Challenges

P. Fossa, P. D’Ursi, 2022, Biomolecules.

Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance

Alessandro Orro, Luciano Milanesi, Gabriele Trombetti, 2018, Molecules.

Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors

P. Fossa, E. Cichero, F. Musumeci, 2023, International journal of molecular sciences.

Characterization of sulfur compounds and antiviral activity against Tomato brown rugose fruit virus (ToBRFV) of Italian “Vessalico” garlic compared to other cultivars and landrace

G. Drava, P. Fossa, N. Maggi, 2022, LWT.

Exhaustive 3D-QSAR analyses as a computational tool to explore the potency and selectivity profiles of thieno[3,2-d]pyrimidin-4(3H)-one derivatives as PDE7 inhibitors

P. Fossa, E. Cichero, C. Brullo, 2016 .

A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists

R. Gainetdinov, S. Franchini, P. Fossa, 2016 .

Exploitation of a novel biosensor based on the full-length human F508del-CFTR with computational studies, biochemical and biological assays for the characterization of a new Lumacaftor/Tezacaftor analogue

Paolo Bergese, Alessandro Orro, Luciano Milanesi, 2019 .

Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT6 receptor interaction.

J. Brea, P. Fossa, E. Cichero, 2023, Bioorganic & medicinal chemistry.

Synthesis, antimicrobial activity and molecular modeling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]-1,5-diphenyl-1H-pyrazoles.

P. Fossa, S. Schenone, R. Loddo, 2004, Bioorganic & medicinal chemistry.

Molecular Docking and QSAR Studies as Computational Tools Exploring the Rescue Ability of F508del CFTR Correctors

Annalisa Salis, Monica Casale, Paola Fossa, 2020, International journal of molecular sciences.

Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells.

P. Fossa, C. Brullo, S. Schenone, 2004, Journal of medicinal chemistry.

Computational studies of the binding mode and 3D-QSAR analyses of symmetric formimidoester disulfides: a new class of non-nucleoside HIV-1 reverse transcriptase inhibitor

P. Fossa, E. Cichero, L. Mosti, 2009, Journal of molecular modeling.

A Boron Delivery Antibody (BDA) with Boronated Specific Residues: New Perspectives in Boron Neutron Capture Therapy from an In Silico Investigation

L. Milanesi, P. Fossa, A. Orro, 2021, Cells.

Structure–Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma

S. Franchini, P. Fossa, E. Cichero, 2017, ChemMedChem.

Structural basis for selective PDE 3 inhibition: a docking study

P. Fossa, F. Giordanetto, L. Mosti, 2002 .

Exploring the effectiveness of novel benzimidazoles as CB2 ligands: synthesis, biological evaluation, molecular docking studies and ADMET prediction.

P. Fossa, E. Cichero, A. Ligresti, 2018, MedChemComm.

New pyrazolo[3,4-b]pyridones as selective A(1) adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies.

Silvia Schenone, Paola Fossa, Claudia Martini, 2005, Organic & biomolecular chemistry.

Exploring the molecular basis of selectivity in A1 adenosine receptors agonists: a case study

Fabrizio Giordanetto, Paola Fossa, Giulia Menozzi, 2003, J. Comput. Aided Mol. Des..

Design and synthesis of 4,5,6,7-tetrahydro-1H-1,2-diazepin-7-one derivatives as a new series of Phosphodiesterase 4 (PDE4) inhibitors.

P. Fossa, F. Giordanetto, Sara Guariento, 2017, Bioorganic & medicinal chemistry letters.

Docking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors

P. Fossa, E. Cichero, O. Bruno, 2012, Journal of enzyme inhibition and medicinal chemistry.

Exploring the binding features of rimonabant analogues and acyclic CB1 antagonists: docking studies and QSAR analysis

Paola Fossa, Elena Cichero, Giulia Menozzi, 2008, Journal of molecular modeling.

Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles

P. Fossa, E. Cichero, R. Loddo, 2017, Journal of enzyme inhibition and medicinal chemistry.

Novel sulfenamides and sulfonamides based on pyridazinone and pyridazine scaffolds as CB1 receptor ligand antagonists.

P. Fossa, E. Cichero, J. Fernández-Ruiz, 2018, Bioorganic & medicinal chemistry.

Exhaustive CoMFA and CoMSIA analyses around different chemical entities: a ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands

S. Franchini, P. Fossa, E. Cichero, 2017, Journal of enzyme inhibition and medicinal chemistry.

In Silico and In Vitro Evaluation of the Mechanism of Action of Three VX809-Based Hybrid Derivatives as Correctors of the F508del CFTR Protein

P. Fossa, E. Cichero, D. Baroni, 2023, Pharmaceuticals.

Scouting new molecular targets for CFTR therapy: the HSC70/BAG-1 complex. A computational study

P. Fossa, E. Cichero, M. Turco, 2012, Medicinal Chemistry Research.

Synthesis of 4-thiophen-2'-yl-1,4-dihydropyridines as potentiators of the CFTR chloride channel.

P. Fossa, N. Pedemonte, M. Zacchigna, 2009, Bioorganic & medicinal chemistry.