A. W. Schüttelkopf

发表

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes.

A. W. Schüttelkopf, D. V. van Aalten, 2004, Acta crystallographica. Section D, Biological crystallography.

Interactions of LY333531 and other bisindolyl maleimide inhibitors with PDK1.

A. W. Schüttelkopf, D. V. van Aalten, D. Alessi, 2004, Structure.

The structure of the ternary Eg5–ADP–ispinesib complex

A. W. Schüttelkopf, F. Kozielski, S. K. Talapatra, 2012, Acta crystallographica. Section D, Biological crystallography.

Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer.

M. Garnett, M. Drysdale, J. Bower, 2018, Cancer research.

Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope

A. W. Schüttelkopf, D. V. van Aalten, D. W. Brighty, 2008, Retrovirology.

Crystallization and X-ray diffraction measurements on recombinant molbindin, MopII, from Clostridium pasteurianum.

W. Hunter, A. W. Schüttelkopf, D. Boxer, 2001, Acta crystallographica. Section D, Biological crystallography.

Acetazolamide-based fungal chitinase inhibitors

Ian H. Gilbert, I. Gilbert, A. W. Schüttelkopf, 2010, Bioorganic & medicinal chemistry.

Structural insights into mechanism and specificity of O-GlcNAc transferase

A. W. Schüttelkopf, D. V. van Aalten, V. Borodkin, 2008, The EMBO journal.

Bisdionin C-a rationally designed, submicromolar inhibitor of family 18 chitinases.

A. W. Schüttelkopf, D. V. van Aalten, Francesco V Rao, 2011, ACS medicinal chemistry letters.

Screening-based Discovery and Structural Dissection of a Novel Family 18 Chitinase Inhibitor*

Clare Lloyd, A. W. Schüttelkopf, D. V. van Aalten, 2006, Journal of Biological Chemistry.

Structure and mechanism of chitin deacetylase from the fungal pathogen Colletotrichum lindemuthianum.

S. Withers, A. W. Schüttelkopf, D. V. van Aalten, 2006, Biochemistry.

Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins

A. W. Schüttelkopf, D. V. van Aalten, D. W. Brighty, 2011, PLoS pathogens.

Structures of Leishmania major pteridine reductase complexes reveal the active site features important for ligand binding and to guide inhibitor design.

Stephen M Beverley, L. Hardy, W. Hunter, 2005, Journal of molecular biology.

Natural product-guided discovery of a fungal chitinase inhibitor.

A. W. Schüttelkopf, D. V. van Aalten, I. Eggleston, 2010, Chemistry & biology.

Structure and metal-dependent mechanism of peptidoglycan deacetylase, a streptococcal virulence factor

A. W. Schüttelkopf, D. V. van Aalten, J. MacRae, 2005, Proceedings of the National Academy of Sciences of the United States of America.

A novel small-molecule MRCK inhibitor blocks cancer cell invasion

M. Drysdale, J. Bower, A. W. Schüttelkopf, 2014, Cell Communication and Signaling.

ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments.

Charles Simon Bond, Alexander Wolfgang Schüttelkopf, C. Bond, 2009, Acta crystallographica. Section D, Biological crystallography.

TAK1-binding protein 1 is a pseudophosphatase.

P. Cohen, A. W. Schüttelkopf, D. V. van Aalten, 2006, The Biochemical journal.

The active site of O-GlcNAc transferase imposes constraints on substrate sequence

A. W. Schüttelkopf, D. V. van Aalten, J. Alonso, 2015, Nature Structural &Molecular Biology.

Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

A. W. Schüttelkopf, D. V. van Aalten, I. Navratilova, 2013, Open Biology.

Structural Basis of Reduction-dependent Activation of Human Cystatin F*

A. W. Schüttelkopf, D. V. van Aalten, C. Watts, 2006, Journal of Biological Chemistry.

Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis

A. W. Schüttelkopf, D. V. van Aalten, D. Robinson, 2013, Open Biology.

O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis

A. W. Schüttelkopf, D. V. van Aalten, D. Robinson, 2012, Nature chemical biology.

Insight into the Role of Escherichia coli MobB in Molybdenum Cofactor Biosynthesis Based on the High Resolution Crystal Structure*

W. Hunter, A. W. Schüttelkopf, D. Boxer, 2003, Journal of Biological Chemistry.

Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites

Gordon A. Leonard, William N. Hunter, L. Hardy, 2001, Nature Structural Biology.

Human OGA binds substrates in a conserved peptide recognition groove

A. W. Schüttelkopf, D. V. van Aalten, V. Borodkin, 2010, The Biochemical journal.

Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents

M. Drysdale, J. Bower, A. W. Schüttelkopf, 2019, Bioorganic & medicinal chemistry letters.

Crystal structure of activated ModE reveals conformational changes involving both oxyanion and DNA-binding domains.

W. Hunter, A. W. Schüttelkopf, D. Boxer, 2003, Journal of molecular biology.

Passive acquisition of ligand by the MopII molbindin from Clostridium pasteurianum: structures of apo and oxyanion-bound forms.

W. Hunter, A. W. Schüttelkopf, D. Boxer, 2002, The Journal of biological chemistry.

Oxyanion Binding Alters Conformation and Quaternary Structure of the C-terminal Domain of the Transcriptional Regulator ModE

N. C. Price, W. Hunter, A. W. Schüttelkopf, 2001, The Journal of Biological Chemistry.

Molecular Mechanisms of Yeast Cell Wall Glucan Remodeling*

J. Latgé, A. W. Schüttelkopf, D. V. van Aalten, 2009, Journal of Biological Chemistry.

Biological Crystallography the Structure of the Ternary Eg5–adp–ispinesib Complex

A. W. Schüttelkopf, F. Kozielski, S. Talapatra, 2022 .

A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma.

M. Drysdale, J. Bower, A. W. Schüttelkopf, 2018, Cancer research.

MRCK prevents radiation-driven invasion in glioblastoma

J. Bower, A. W. Schüttelkopf, M. Olson, 2021 .

A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma.

M. Drysdale, J. Bower, A. W. Schüttelkopf, 2018, Cancer research.

Human OGA binds substrates in a conserved peptide recognition groove

A. W. Schüttelkopf, D. V. van Aalten, V. Borodkin, 2010, The Biochemical journal.