D. Hoyer

B. Dean, D. Hoyer, A. Gibbons, 2020, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Localization and pharmacological characterization of somatostatin sst2 sites in the rat cerebellum

D. Hoyer, C. Piwko, V. Silke Thoss, 1995, Naunyn-Schmiedeberg's Archives of Pharmacology.

Somatostatin receptors in the developing rat brain.

D. Hoyer, V. Thoss, D. Duc, 1996, European journal of pharmacology.

Identification and SAR of potent and selective non-peptide obeline somatostatin sst1 receptor antagonists.

D. Hoyer, T. Troxler, P. Schoeffter, 2007, Bioorganic & medicinal chemistry letters.

The β-adrenergic receptor in human lymphocytes: Subclassification by the use of a new radio-ligand, (±)−125iodocyanopindolol

D. Hoyer, O. Brodde, K. Bock, 1981 .

The beta-adrenergic receptor in human lymphocytes: subclassification by the use of a new radio-ligand, (+/-)-125 Iodocyanopindolol.

D. Hoyer, O. Brodde, K. Bock, 1981, Life sciences.

Presence of somatostatin sst2 receptors in the developing rat auditory system.

E. Friauf, D. Hoyer, V. Thoss, 1996, Brain research. Developmental brain research.

Design and synthesis of potent thiol-based inhibitors of endothelin converting enzyme-1.

David J. Symonsbergen, D. Hoyer, D. Hoyer, 2000, Bioorganic & medicinal chemistry letters.

Interaction of psychotropic drugs with central 5-HT3 recognition sites: fact or artifact?

D. Hoyer, M. Hamon, L. Schechter, 1989, European journal of pharmacology.

CNS mediated effects of FTY720 (Fingolimod) in EAE

M. Rausch, D. Hoyer, K. Dev, 2007 .

Non-specific uptake of the radioligand 125I-IHYP by intact human lymphocytes: Reversal of the uptake process

D. Hoyer, E. Paietta, J. Schwarzmeier, 1982, Molecular and Cellular Endocrinology.

Linear, Peptidase-Resistantβ2/β3-Di- andα/β3-Tetrapeptide Derivatives with Nanomolar Affinities to a Human Somatostatin Receptor, Preliminary Communication

D. Hoyer, D. Seebach, P. Arvidsson, 2001 .

The cyclo-β-tetrapeptide (β-HPhe-β-HThr-β-HLys-β-HTrp): synthesis, NMR structure in methanol solution, and affinity for human somatostatin receptors

D. Hoyer, D. Seebach, K. Gademann, 2000 .

Somatostatin sst2 receptor knock-out mice: localisation of sst1–5 receptor mRNA and binding in mouse brain by semi-quantitative RT–PCR, in situ hybridisation histochemistry and receptor autoradiography

D. Hoyer, J. Epelbaum, C. Viollet, 2002, Neuropharmacology.

Embryonic and postnatal mRNA distribution of five somatostatin receptor subtypes in the rat brain

D. Hoyer, V. Thoss, D. Duc, 1995, Neuropharmacology.

Pharmacological identity between somatostatin SS-2 binding sites and SSTR-1 receptors.

D. Hoyer, J. Reubi, H. Lübbert, 1995, European journal of pharmacology.

Is the sumatriptan (GR 43175)-induced endothelium-dependent relaxation of pig coronary arteries mediated by 5-HT1D receptors?

D. Hoyer, P. Schoeffter, 1989, European journal of pharmacology.

Characterisation of human recombinant somatostatin receptors. 4. Modulation of phospholipase C activity

D. Hoyer, S. Siehler, D. Hoyer, 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.

5‐HT1‐like receptors mediate 5‐hydroxytryptamine‐induced contraction of guinea‐pig isolated iliac artery

D. Hoyer, P. Schoeffter, A. Stoll, 1991, British journal of pharmacology.

Subtypes of alpha 1-adrenoceptors in hippocampus of pigs, guinea-pigs, calves and humans: regional differences.

J. Palacios, D. Hoyer, W. Ford, 1990, European journal of pharmacology.

Serotonin increases the production of inositol phosphates and mobilises calcium via the 5-HT2 receptor in A7r5 smooth muscle cells

D. Hoyer, U. Rüegg, J. Creba, 1986, Naunyn-Schmiedeberg's Archives of Pharmacology.

Agonist/antagonist interactions with cloned human 5-HT1A receptors: variations in intrinsic activity studied in transfected HeLa cells

D. Hoyer, A. Fargin, P. Schoeffter, 1992, Naunyn-Schmiedeberg's Archives of Pharmacology.

Therapeutic Possibilities with Serotonergic Drugs

A. Ford, D. Hoyer, D. Clarke, 1995 .

Effect of somatostatin on nitric oxide production in human retinal pigment epithelium cell cultures.

D. Hoyer, M. Tsilimbaris, G. Kolios, 2004, Investigative ophthalmology & visual science.

Evidence for the presence of 5-HT1B receptor messenger RNA in neurons of the rat trigeminal ganglia.

D. Hoyer, B. Landwehrmeyer, A. Bruinvels, 1992, European journal of pharmacology.

Characterization of functional responses in A9 cells transfected with cloned rat 5-HT1C receptors

J. Palacios, D. Hoyer, H. Boddeke, 1993, Naunyn-Schmiedeberg's Archives of Pharmacology.

Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.

D. Hoyer, R. Cappai, G. Ciccotosto, 2018, ACS chemical neuroscience.

Differential expression of five somatostatin receptor subtypes, SSTR1-5, in the CNS and peripheral tissue.

D. Hoyer, F. Raulf, J. Pérez, 1994, Digestion.

Cloning, expression and pharmacological characterisation of the mouse somatostatin sst5 receptor

D. Hoyer, K. Seuwen, R. Bouhelal, 2000, Neuropharmacology.

CNS mediated effects of Fingolimod (FTY720) in EAE

M. Rausch, D. Hoyer, K. Dev, 2007 .

[125I]SCH 23982, a 'selective' D-1 receptor antagonist, labels with high affinity 5-HT1C sites in pig choroid plexus.

D. Hoyer, A. Karpf, 1988, European journal of pharmacology.

Localisation by autoradiography of neuronal 5-HT3 receptors in the mouse CNS.

J. Palacios, D. Hoyer, C. Waeber, 1988, European journal of pharmacology.

International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

B. Roth, E. Lambe, M. Camilleri, 2020, Pharmacological Reviews.

International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. IX. Recommendations on terms and symbols in quantitative pharmacology.

D. Jenkinson, D. Hoyer, E. Barnard, 1995, Pharmacological reviews.

Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine

D. Hoyer, T. Bártfai, M. C. Morale, 2007, Molecular Psychiatry.

Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites

E. Schlicker, D. Hoyer, E. Schlicker, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Involvement of the Sst 1 Somatostatin Receptor Subtype in the Intrahypothalamic Neuronal Network Regulating Growth Hormone Secretion : An in Vitro and in Vivo Antisense Study

D. Hoyer, Z. Csaba, P. Dournaud, 2000 .

Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.

D. Hoyer, Y. Satoh, D. Hoyer, 2000, Journal of medicinal chemistry.

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

P P Humphrey, P R Saxena, G. Martin, 1994, Pharmacological reviews.

Molecular biology of 5-HT receptors

Daniel Hoyer, D. Hoyer, Jason Hannon, 2008, Behavioural Brain Research.

Molecular, pharmacological and functional diversity of 5-HT receptors

Daniel Hoyer, G. Martin, D. Hoyer, 2002, Pharmacology Biochemistry and Behavior.

Classification and nomenclature of 5-HT receptors: a comment on current issues

G. Martin, D. Hoyer, 1995, Behavioural Brain Research.

Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia.

M. Fendt, S. Hintermann, D. Hoyer, 2013, Journal of medicinal chemistry.

Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues.

Horst Kessler, Raz Jelinek, Jayanta Chatterjee, 2008, Angewandte Chemie.

New Open‐Chain and Cyclic Tetrapeptides, Consisting of α‐, β2‐, and β3‐Amino‐Acid Residues, as Somatostatin Mimics – A Survey

D. Hoyer, B. Jaun, D. Seebach, 2008 .

Neuropeptides and Neuropeptide Receptors: Drug Targets, and Peptide and Non‐Peptide Ligands: a Tribute to Prof. Dieter Seebach

D. Hoyer, T. Bártfai, 2012, Chemistry & biodiversity.

Synthesis and Biological Evaluation of a Cyclo-β-tetrapeptide as a Somatostatin Analogue.

D. Hoyer, D. Seebach, K. Gademann, 1999, Angewandte Chemie.

Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (-)[125I]iodocyanopindolol, [3H]mesulergine and [3H]ketanserin.

D. Hoyer, H. Kalkman, G. Engel, 1985, European journal of pharmacology.

Synthesis and structure−activity relationships of teixobactin

D. Hoyer, J. Li, R. Payne, 2019, Annals of the New York Academy of Sciences.

The impact of backbone N‐methylation on the structure‐activity relationship of Leu10‐teixobactin

D. Hoyer, J. Li, T. Velkov, 2019, Journal of peptide science : an official publication of the European Peptide Society.

Lemborexant. Dual orexin receptor antagonist, Treatment of insomnia

D. Hoyer, L. Jacobson, 2018 .

Excitatory Amino Acids and Their Antagonists

P. Shizgal, S. Nieuwenhuis, Sarah L Parylak, 2015 .

A proposed new nomenclature for 5-HT receptors.

D. Hoyer, P. Hartig, P. Humphrey, 1993, Trends in pharmacological sciences.

The somatostatin sst1 receptor: an autoreceptor for somatostatin in brain and retina?

D. Hoyer, P. Bagnoli, J. Epelbaum, 2006, Pharmacology & therapeutics.

The pharmacological properties of the presynaptic serotonin autoreceptor in the pig brain cortex conform to the 5-HT1D receptor subtype

D. Hoyer, K. Fink, E. Schlicker, 1989, Naunyn-Schmiedeberg's Archives of Pharmacology.

Interfering with the brain: use of RNA interference for understanding the pathophysiology of psychiatric and neurological disorders.

D. Hoyer, J. Cryan, D. Thakker, 2006, Pharmacology & therapeutics.

Molecular cloning and pharmacological characterization of a somatostatin receptor subtype in the gymnotiform fish Apteronotus albifrons.

E. M. Jones, D. Hoyer, K. Seuwen, 1999, General and comparative endocrinology.

Recovery of emotional behaviour in neural cell adhesion molecule (NCAM) null mutant mice through transgenic expression of NCAM180

K. Obata, D. Hoyer, M. Schachner, 2000, The European journal of neuroscience.

Anxiety and increased 5-HT1A receptor response in NCAM null mutant mice.

D. Hoyer, M. Schachner, C. Wotjak, 1999, Journal of neurobiology.

Distribution of 5-HT receptors in the central nervous system: an update

G. Mengod, D. Hoyer, M. Vilaró, 2020 .

Distribution of 5-HT Receptors in the Central Nervous System

Daniel Hoyer, G. Mengod, D. Hoyer, 2010 .

5-HT-3B Receptor

D. Hoyer, 2008 .

Selective effects of benzodiazepines on the acquisition of conditioned taste aversion compared to attenuation of neophobia in C57BL/6 mice

P. Kelly, D. Hoyer, Z. Callaerts-Vegh, 2009, Psychopharmacology.

mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity

M. Fendt, P. Kelly, F. Natt, 2008, Molecular Psychiatry.

Personality: Neurobehavioural Foundation and Pharmacological Protocols

Stephanie A. Carmack, C. McDougle, D. Posey, 2014 .

A Comparative Study of Outer Membrane Proteome between Paired Colistin-Susceptible and Extremely Colistin-Resistant Klebsiella pneumoniae Strains.

D. Hoyer, T. Velkov, M. Baker, 2018, ACS infectious diseases.

Global Down-Regulation of Gene Expression in the Brain Using RNA Interference, with Emphasis on Monoamine Transporters and GPCRs: Implications for Target Characterization in Psychiatric and Neurological Disorders

Dieter Huesken, F. Natt, D. Hoyer, 2006, Journal of receptor and signal transduction research.

Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference.

F. Natt, D. Hoyer, J. Cryan, 2004, Proceedings of the National Academy of Sciences of the United States of America.

RNA interference as a therapeutic strategy for treating CNS disorders

D. Hoyer, K. Dev, 2006, Drug Discovery Today: Therapeutic Strategies.

The selective nicotinic acetylcholine receptor α7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain

D. Hoyer, G. Bilbe, K. Lingenhoehl, 2009, Neuropharmacology.

5-Hydroxytryptamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

G. Martin, J. Hensler, R. Hen, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Serotonin receptors and systems: endless diversity?

D. Hoyer, J. Hannon, 2002 .

Fish somatostatin sst3 receptor: comparison of radioligand and GTPgammaS binding, adenylate cyclase and phospholipase C activities reveals different agonist-dependent pharmacological signatures.

D. Hoyer, S. Siehler, C. Nunn, 2005, Autonomic & autacoid pharmacology.

Identification and characterization of a type five-like somatostatin receptor in goldfish pituitary

D. Hoyer, J. Rivier, Xin-wei Lin, 2002, Molecular and Cellular Endocrinology.

Serotonin receptors in the human brain. II. Characterization and autoradiographic localization of 5-HT1C and 5-HT2 recognition sites

J. Palacios, D. Hoyer, Á. Pazos, 1986, Brain Research.

Three distinct subtypes of serotonergic receptors mediate the triphasic blood pressure response to serotonin in rats.

D. Hoyer, H. Kalkman, G. Engel, 1984, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampus

D. Hoyer, R. Markstein, G. Engel, 1986, Naunyn-Schmiedeberg's Archives of Pharmacology.

Serotonin receptors in the human brain. I. Characterization and autoradiographic localization of 5-HT1A recognition sites. Apparent absence of 5-HT1B recognition sites

J. Palacios, D. Hoyer, Á. Pazos, 1986, Brain Research.

5-HT1D receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in calf substantia nigra.

D. Hoyer, P. Schoeffter, 1988, European journal of pharmacology.

The binding of serotonergic ligands to the porcine choroid plexus: characterization of a new type of serotonin recognition site.

J. Palacios, D. Hoyer, Á. Pazos, 1984, European journal of pharmacology.

Brain somatostatin: a candidate inhibitory role in seizures and epileptogenesis

D. Hoyer, A. Vezzani, 1999, The European journal of neuroscience.

5-Hydroxytryptamine (5-HT)-induced endothelium-dependent relaxation of pig coronary arteries is mediated by 5-HT receptors similar to the 5-HT1D receptor subtype.

D. Hoyer, P. Schoeffter, 1990, The Journal of pharmacology and experimental therapeutics.

Molecular pharmacology and biology of 5-HT1C receptors.

D. Hoyer, 1988, Trends in pharmacological sciences.

5-Hydroxytryptamine Receptor Histochemistry: Comparison of Receptor mRNA Distribution and Radioligand Autoradiography in the Brain

J. Palacios, G. Mengod, D. Hoyer, 2000 .

Alignment of receptor nomenclature with the human genome: classification of 5-HT1B and 5-HT1D receptor subtypes.

G. Martin, D. Hoyer, P. Hartig, 1996, Trends in pharmacological sciences.

Contemporary Anti-Ebola Drug Discovery Approaches and Platforms.

J. Baell, D. Hoyer, T. Velkov, 2018, ACS infectious diseases.

Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse

D. Hoyer, J. Cryan, D. Thakker, 2013, Neuropharmacology.

Partial agonists, full agonists, antagonists: dilemmas of definition.

D. Hoyer, H. Boddeke, Hendrikus Boddeke, 1993, Trends in pharmacological sciences.

Toxic Epidermal Necrolysis Caused by Allopurinol: A Serious but Still Underestimated Adverse Reaction

D. Hoyer, D. Sedding, S. Nuding, 2021, The American journal of case reports.

Hyperdopaminergia and altered locomotor activity in GABAB1‐deficient mice

D. Hoyer, P. Pévet, M. Gassmann, 2006, Journal of neurochemistry.

Inhibition of 5-carboxamidotryptamine-induced relaxation of guinea-pig ileum correlates with [125I]LSD binding.

D. Hoyer, H. Kalkman, G. Engel, 1986, European journal of pharmacology.

Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain

D. Hoyer, K. Seuwen, H. Lübbert, 1993, FEBS letters.

siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

F. Natt, D. Hoyer, J. Cryan, 2005, Molecular Psychiatry.

Interaction of the alpha-adrenoceptor agonist oxymetazoline with serotonin 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors.

D. Hoyer, P. Schoeffter, 1991, European journal of pharmacology.

Somatostatin-28 modulates prepulse inhibition of the acoustic startle response, reward processes and spontaneous locomotor activity in rats

M. Geyer, D. Hoyer, A. Markou, 2010, Neuropeptides.

Increased exploratory activity of APP23 mice in a novel environment is reversed by siRNA

P. Kelly, F. Natt, M. Staufenbiel, 2008, Brain Research.

AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation

D. Hoyer, G. Bilbe, K. Lingenhoehl, 2015, British journal of pharmacology.

Hypnotics with novel modes of action

D. Hoyer, L. Jacobson, Andrew Allen, 2019, British journal of clinical pharmacology.

Hypocretins (orexins): The ultimate translational neuropeptides

D. Hoyer, L. de Lecea, L. Jacobson, 2022, Journal of internal medicine.

Molecular Mechanisms of Neurotoxicity Induced by Polymyxins and Chemoprevention.

Jianzhong Shen, D. Hoyer, R. Cappai, 2018, ACS chemical neuroscience.

Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis.

D. Hoyer, G. Bilbe, K. Dev, 2008, Pharmacology & therapeutics.

Species differences in the pharmacology of terminal 5-HT autoreceptors in mammalian brain.

D. Middlemiss, D. Hoyer, 1989, Trends in pharmacological sciences.

The potentially beneficial central nervous system activity profile of ivacaftor and its metabolites

D. Hoyer, B. Button, J. Li, 2018, ERJ Open Research.

Characterisation of the fish sst3 receptor, a member of the SRIF1 receptor family: atypical pharmacological features

D. Hoyer, K. Seuwen, S. Siehler, 1999, Neuropharmacology.

Molecular pharmacology of somatostatin receptors

D. Hoyer, H. Lübbert, C. Bruns, 1994, Naunyn-Schmiedeberg's Archives of Pharmacology.

Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst 1 receptor.

D. Hoyer, T. Troxler, A. Enz, 2008, Bioorganic & medicinal chemistry letters.

SAR of the arylpiperazine moiety of obeline somatostatin sst1 receptor antagonists.

D. Hoyer, T. Troxler, A. Enz, 2007, Bioorganic & medicinal chemistry letters.

The somatostatin receptor (sst1) modulates the release of somatostatin in the nucleus accumbens of the rat

D. Hoyer, K. Thermos, A. Vasilaki, 2004, Neuropharmacology.

Somatostatin receptor subtypes 2 and 4 affect seizure susceptibility and hippocampal excitatory neurotransmission in mice

P. Dutar, J. Billard, D. Hoyer, 2002, The European journal of neuroscience.

Distribution and characterisation of somatostatin receptor mRNA and binding sites in the brain and periphery

D. Hoyer, S. Siehler, D. Feuerbach, 2000, Journal of Physiology-Paris.

Cloning, expression and pharmacological characterisation of the mouse somatostatin sst(5) receptor.

D. Hoyer, K. Seuwen, R. Bouhelal, 2000, Neuropharmacology.

Localization and pharmacological characterization of somatostatin recognition sites in the human cerebellum

D. Hoyer, V. Thoss, A. Probst, 1996, Neuropharmacology.

Co-expression of somatostatin SSTR-3 and SSTR-4 receptor messenger RNAs in the rat brain

D. Hoyer, J. Pérez, 1995, Neuroscience.

Somatostatin receptor 1 selective analogues: 2. N(alpha)-Methylated scan.

D. Hoyer, J. Rivier, J. Reubi, 2005, Journal of medicinal chemistry.

Characterization of the 5-HT1B recognition site in rat brain: binding studies with (-)[125I]iodocyanopindolol.

D. Hoyer, H. Kalkman, G. Engel, 1985, European journal of pharmacology.

Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues.

R. Riek, D. Hoyer, J. Rivier, 2009, Journal of medicinal chemistry.

The serotonin 5-HT1D receptor: A progress review

J. Palacios, D. Hoyer, C. Waeber, 1990, Neurochemical Research.

Autoradiography of 5-HT receptors: A critical appraisal

J. Palacios, G. Mengod, D. Hoyer, 1991, Neurochemistry International.

The Rostral Anterior Cingulate Cortex Modulates the Efficiency of Amygdala-Dependent Fear Learning

A. Grace, S. Bissière, D. Hoyer, 2008, Biological Psychiatry.

5-HT-2A Receptor

D. Hoyer, 2008 .

5-HT-1B Receptor

D. Hoyer, 2008 .

The role of α2‐adrenoceptor antagonism in the anti‐cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat

D. Hoyer, M. Tricklebank, H. Kalkman, 1998, British journal of pharmacology.

Calcineurin inhibits desensitization of cloned rat 5-HT1C receptors

J. Palacios, D. Hoyer, H. Boddeke, 1993, Naunyn-Schmiedeberg's Archives of Pharmacology.

Orexin OX2 Receptor Antagonists as Sleep Aids.

D. Hoyer, L. Jacobson, Suio Chen, 2017, Current topics in behavioral neurosciences.

Orexin in sleep, addiction and more: Is the perfect insomnia drug at hand?

D. Hoyer, L. Jacobson, 2013, Neuropeptides.

Withdrawal from chronic amphetamine induces Depressive-Like behavioral effects in rodents

D. Hoyer, J. Cryan, A. Markou, 2003, Biological Psychiatry.

5-Hydroxytryptamine Receptors

D. Hoyer, 2008 .

Hippocampal 5‐HT7 receptors signal phosphorylation of the GluA1 subunit to facilitate AMPA receptor mediated‐neurotransmission in vitro and in vivo

D. Hoyer, N. Barnes, L. Carboni, 2016, British journal of pharmacology.

Interactions of agonists with beta-adrenergic receptors on S49 lymphoma cells.

P. Molinoff, D. Hoyer, E. Reynolds, 1985, Advances in cyclic nucleotide and protein phosphorylation research.

Somatostatin, Alzheimer's disease and cognition: An old story coming of age?

D. Hoyer, J. Guillou, F. Gastambide, 2009, Progress in Neurobiology.

Curcumin attenuates colistin-induced peripheral neurotoxicity in mice.

Jianzhong Shen, D. Hoyer, T. Velkov, 2020, ACS infectious diseases.

Astrocytes: Adhesion Molecules and Immunomodulation.

D. Hoyer, S. Liddelow, 2016, Current drug targets.

Manipulation of REM sleep via orexin and GABAA receptor modulators differentially affects fear extinction in mice: effect of stable versus disrupted circadian rhythm.

Jeremy A. Metha, S. Drummond, D. Hoyer, 2021, Sleep.

Animal Models of Addiction and Neuropsychiatric Disorders and Their Role in Drug Discovery: Honoring the Legacy of Athina Markou

G. Koob, D. Hoyer, P. Kenny, 2018, Biological Psychiatry.

Separating Probability and Reversal Learning in a Novel Probabilistic Reversal Learning Task for Mice

Peter Bossaerts, Carsten Murawski, Daniel Hoyer, 2020, Frontiers in Behavioral Neuroscience.

α1-adrenoceptors in the mammalian brain: similar pharmacology but different distribution in rodents and primates

J. Palacios, D. Hoyer, R. Cortės, 1987, Brain Research.

Centrally acting hypotensive agents with affinity for 5‐HT1A binding sites inhibit forskolin‐stimulated adenylate cyclase activity in calf hippocampus

D. Hoyer, P. Schoeffter, Philippe Schoeffter, 1988, British journal of pharmacology.

Interaction of arylpiperazines with 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors: do discriminatory 5-HT1B receptor ligands exist?

D. Hoyer, P. Schoeffter, 1989, Naunyn-Schmiedeberg's Archives of Pharmacology.

5-HT-2C Receptor

D. Hoyer, 2008 .

Extended Radioligand Binding Profile of Iloperidone: A Broad Spectrum Dopamine/Serotonin/Norepinephrine Receptor Antagonist for the Management of Psychotic Disorders

D. Hoyer, H. Kalkman, N. Subramanian, 2001, Neuropsychopharmacology.

Pharmacological characterisation of 5-HT receptors positively coupled to adenylyl cyclase in the rat hippocampus

D. Hoyer, C. Kohler, M. Yoshioka, 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.

Somatostatin receptors in the Rhesus monkey brain: localization and pharmacological characterization

Daniel Hoyer, D. Hoyer, C. Piwko, 1996, Naunyn-Schmiedeberg's Archives of Pharmacology.

Blunted 5-HT1A receptor-mediated responses and antidepressant-like behavior in mice lacking the GABAB1a but not GABAB1b subunit isoforms

D. Hoyer, J. Cryan, B. Bettler, 2017, Psychopharmacology.

Distribution of Serotonin Receptors

J. Palacios, G. Mengod, D. Hoyer, 1990, Annals of the New York Academy of Sciences.

Binding characteristics of (+)-, (±)- and (-)-[125Iodo] cyanopindolol to guinea-pig left ventricle membranes

D. Hoyer, G. Engel, R. Berthold, 1982, Naunyn-Schmiedeberg's Archives of Pharmacology.

Paroxetine combined with a 5-HT1A receptor antagonist reversed reward deficits observed during amphetamine withdrawal in rats

A. Harrison, D. Hoyer, A. Markou, 2005, Psychopharmacology.

5.HT1 receptors in the vertebrate brain

J. Palacios, D. Hoyer, C. Waeber, 1989, Naunyn-Schmiedeberg's Archives of Pharmacology.

Decreased Orexin Receptor 1 mRNA Expression in the Locus Coeruleus in Both Tau Transgenic rTg4510 and Tau Knockout Mice and Accompanying Ascending Arousal System Tau Invasion in rTg4510.

D. Hoyer, C. Nowell, L. Jacobson, 2020, Journal of Alzheimer's disease : JAD.

siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

F. Natt, D. Hoyer, J. Cryan, 2005, Molecular Psychiatry.

The novel 5‐HT1A receptor antagonist, SDZ 216–525, decreases 5‐HT release in rat hippocampus in vivo

J. Fozard, D. Hoyer, T. Sharp, 1993, British journal of pharmacology.

[125I]BE 2254, a new high affinity radioligand for alpha 1-adrenoceptors.

D. Hoyer, G. Engel, 1981, European journal of pharmacology.

Mesulergine, a selective serotonin-2 ligand in the rat cortex, does not label these receptors in porcine and human cortex: evidence for species differences in brain serotonin-2 receptors.

J. Palacios, D. Hoyer, Á. Pazos, 1984, European journal of pharmacology.

Autoradiographic characterisation and localisation of 5-HT1D compared to 5-HT1B binding sites in rat brain

J. Palacios, D. Hoyer, A. Bruinvels, 1993, Naunyn-Schmiedeberg's Archives of Pharmacology.

5-Hydroxytryptamine 5-HT1B and 5-HT1D receptors mediating inhibition of adenylate cyclase activity

D. Hoyer, P. Schoeffter, 1989, Naunyn-Schmiedeberg's Archives of Pharmacology.

Molecular pharmacology of 5-HT1D recognition sites: Radioligand binding studies in human, pig and calf brain membranes

J. Palacios, D. Hoyer, C. Waeber, 1988, Naunyn-Schmiedeberg's Archives of Pharmacology.

5-HT-4 Receptor

D. Hoyer, 2008 .

5-HT-2B Receptor

D. Hoyer, 2008 .

5-Hydroxytryptamine receptors in GtoPdb v.2023.1

G. Martin, J. Hensler, B. Roth, 2023, IUPHAR/BPS Guide to Pharmacology CITE.

Serotonin 5-HT3, 5-HT4, and 5-HT-M receptors.

D. Hoyer, 1990, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

Suvorexant for the treatment of insomnia

D. Hoyer, L. Jacobson, G. E. Callander, 2014, Expert review of clinical pharmacology.

DUAL OREXIN RECEPTOR ANTAGONIST ALMOREXANT INDUCES SLEEP The Dual Orexin Receptor Antagonist Almorexant Induces Sleep and Decreases Orexin-Induced Locomotion by Blocking Orexin 2 Receptors

M. Fendt, D. Hoyer, C. Gee, 2012 .

[125Iodo]BE 2254, a new radioligand for alpha 1-adrenoceptors.

D. Hoyer, G. Engel, 1982, Journal of cardiovascular pharmacology.

T-2 toxin neurotoxicity: role of oxidative stress and mitochondrial dysfunction

Jianzhong Shen, D. Hoyer, T. Velkov, 2019, Archives of Toxicology.

Serotonin 5‐HT1D Receptors

J. Palacios, D. Hoyer, C. Waeber, 1990, Annals of the New York Academy of Sciences.

Competitive interaction of agonists and antagonists with 5-HT3 recognition sites in membranes of neuroblastoma cells labelled with [3H]ICS 205-930.

D. Hoyer, H. Neijt, A. Karpf, 1989, Journal of receptor research.

Orexin Receptor Antagonists

D. Hoyer, L. Jacobson, 2017, Current Sleep Medicine Reports.

Emerging use of non-viral RNA interference in the brain.

D. Hoyer, J. Cryan, D. Thakker, 2007, Biochemical Society transactions.

Somatostatin receptors in GtoPdb v.2023.1

D. Hoyer, S. Schulz, S. Melmed, 2023, IUPHAR/BPS Guide to Pharmacology CITE.

Comparison of functional profiles at human recombinant somatostatin sst2 receptor: simultaneous determination of intracellular Ca2+ and luciferase expression in CHO‐K1 cells

D. Hoyer, D. Cervia, R. Bouhelal, 2004, British journal of pharmacology.

Reward motivation and cognitive flexibility in tau null-mutation mice

Jeremy A. Metha, D. Hoyer, A. Lawrence, 2020, Neurobiology of Aging.

Syntheses and biological activities of sandostatin analogs containing stereochemical changes in positions 6 or 8.

D. Hoyer, J. Taylor, B. Morgan, 2000, Biopolymers.

5-HT-1A Receptor

D. Hoyer, 2008 .

Changes of AMPA receptors in MPTP monkeys with levodopa-induced dyskinesias

L. Grégoire, D. Hoyer, B. Ouattara, 2010, Neuroscience.

5-HT-1D Receptor

D. Hoyer, 2008 .

Circadian disruption impairs fear extinction and memory of conditioned safety in mice

S. Drummond, D. Hoyer, A. Phillips, 2020, Behavioural Brain Research.

Sex differences in mouse models of fear inhibition: Fear extinction, safety learning, and fear–safety discrimination

S. Drummond, D. Hoyer, L. Jacobson, 2019, British journal of pharmacology.

Coupling of human nicotinic acetylcholine receptors α7 to calcium channels in GH3 cells

K. Lingenhöhl, D. Hoyer, J. Mosbacher, 2005, Neuropharmacology.

Receptor modification in the brains of spontaneously hypertensive and Wistar-Kyoto rats: regionally specific and selective increase in cerebellar beta 2-adrenoceptors.

J. Palacios, D. Hoyer, F. Bühler, 1990, British journal of clinical pharmacology.

Synthese und biologische Evaluation eines Cyclo‐β‐tetrapeptids als Somatostatin‐Analogon

D. Hoyer, D. Seebach, K. Gademann, 1999 .

Visualization of a novel serotonin recognition site (5-HT1D) in the human brain by autoradiography

J. Palacios, D. Hoyer, A. Probst, 1988, Neuroscience Letters.

A comparative autoradiographic study of 5-HT1D binding sites in human and guinea-pig brain using different radioligands.

J. Palacios, D. Hoyer, A. Probst, 1994, Brain research. Molecular brain research.

Homogeneous 5-HT1D recognition sites in the human substantia nigra identified with a new iodinated radioligand.

J. Palacios, D. Hoyer, C. Waeber, 1991, European journal of pharmacology.

Functional effects of d-Phe-c[Cys-Tyr-d-Trp-Lys-Val-Cys]-Trp-NH2 and differential changes in somatostatin receptor messenger RNAs, binding sites and somatostatin release in kainic acid-treated rats

D. Hoyer, A. Vezzani, G. Civenni, 1995, Neuroscience.

5-HT Receptor Nomenclature: Naming Names, Does It Matter? A Tribute to Maurice Rapport.

D. Hoyer, 2017, ACS chemical neuroscience.

5-Hydroxytryptamine1 recognition sites in rat brain: Heterogeneity of non-5-hydroxytryptamine1a/1c binding sites revealed by quantitative receptor autoradiography

J. Palacios, D. Hoyer, A. Bruinvels, 1993, Neuroscience.

5-HT1D binding sites in various species: similar pharmacological profile in dog, monkey, calf, guinea-pig and human brain membranes

J. Palacios, D. Hoyer, A. Bruinvels, 1992, Naunyn-Schmiedeberg's Archives of Pharmacology.

“5-HT1R” or 5-HT1D sites? Evidence for 5-HT 1D binding sites in rabbit brain

J. Palacios, D. Hoyer, C. Waeber, 1992, Naunyn-Schmiedeberg's Archives of Pharmacology.

Direct visualization of serotonin1D receptors in the human brain using a new iodinated radioligand.

J. Palacios, D. Hoyer, C. Waeber, 1992, Brain research. Molecular brain research.

5-HT1DReceptor Subtypes

J. Palacios, D. Hoyer, A. Bruinvels, 1993 .

GR 43175: A preferential 5‐HT1D agent in monkey and human brains as shown by autoradiography

J. Palacios, D. Hoyer, C. Waeber, 1989, Synapse.

[3H]ketanserin labels serotonin 5-HT2 and alpha 1-adrenergic receptors in human brain cortex.

J. Palacios, D. Hoyer, P. Vos, 1987, Journal of cardiovascular pharmacology.

Medicinal chemistry of somatostatin analogs leading to the DTPA and DOTA conjugates of the multi-receptor-ligand SOM230.

D. Hoyer, R. Kneuer, C. Bruns, 2005, Journal of Endocrinological Investigation.

High affinity of SDZ HTF-919 related molecules for calf and human caudate 5-HT4 receptors.

D. Hoyer, A. Probst, H. Mattes, 1998, Annals of the New York Academy of Sciences.

A Reappraisal of 5-HT Receptor Classification

D. Hoyer, P. Hartig, P. Humphrey, 1993 .

Selective Agonists and Antagonists at 5-Hydroxytryptamine Receptor Subtypes

D. Hoyer, B. Richardson, 1990 .

Identification of a 5-HT1 recognition site in human brain membranes different from 5-HT1A, 5-HT1B and 5-HT1C sites

J. Palacios, D. Hoyer, Á. Pazos, 1988, Neuroscience Letters.

Neuropeptides and Neuropeptide Receptors: Drug Targets, and Peptide and Non‐Peptide Ligands: a Tribute to Prof. Dieter Seebach

D. Hoyer, T. Bártfai, 2012, Chemistry and Biodiversity.

siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

F. Natt, D. Hoyer, J. Cryan, 2005 .

SRA880, in vitro characterization of the first non-peptide somatostatin sst1 receptor antagonist

D. Hoyer, T. Troxler, R. Bouhelal, 2004, Neuroscience Letters.

Lack of evidence for cross-competition between vasoactive intestinal peptide and somatostatin at their respective receptors.

D. Hoyer, J. Reubi, B. Waser, 2001, European journal of pharmacology.

5-HT-1E Receptor

D. Hoyer, 2008 .

Editorial: Reporting guidelines for psychopharmacology

T. Robbins, I. Lucki, D. Hoyer, 2016, Psychopharmacology.

5-HT-1F Receptor

D. Hoyer, 2008 .

Visualization of Serotonin Receptor Binding and Their Messenger RNA’S in the Mammalian Brain: An Update

J. Palacios, G. Mengod, D. Hoyer, 1990 .

Animal Models of Addiction and Neuropsychiatric Disorders and Their Role in Drug Discovery: Honoring the Legacy of Athina Markou

G. Koob, D. Hoyer, P. Kenny, 2018, Biological Psychiatry.

Design, synthesis, and biological activities of potent and selective somatostatin analogues incorporating novel peptoid residues.

O. Ziv, D. Hoyer, J. Taylor, 1998, Journal of medicinal chemistry.

Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues.

J. Brueggen, D. Hoyer, H. Kessler, 2008, Angewandte Chemie.

Somatostatin-28 modulates prepulse inhibition of the acoustic startle response, reward processes and spontaneous locomotor activity in rats

M. Geyer, D. Hoyer, A. Markou, 2010, Neuropeptides.

The potentially beneficial central nervous system activity profile of ivacaftor and its metabolites

D. Hoyer, B. Button, J. Li, 2018, ERJ Open Research.

The serotonin 5-HT4 receptor. 1. Design of a new class of agonists and receptor map of the agonist recognition site.

K. Buchheit, D. Hoyer, H. Pfannkuche, 1995, Journal of Medicinal Chemistry.

[125I]LSD labels 5-HT1C recognition sites in pig choroid plexus membranes. Comparison with [3H]mesulergine and [3H]5-HT binding

J. Palacios, D. Hoyer, Á. Pazos, 1986, Neuroscience Letters.

Antidepressants Influence Somatostatin Levels and Receptor Pharmacology in Brain

D. Hoyer, C. Spyraki, A. Kastellakis, 2009, Neuropsychopharmacology.

Hippocampal 5-HT 7 receptors signal phosphorylation of the GluA 1 subunit to facilitate AMPA receptor mediated-neurotransmission in vitro and in vivo

D. Hoyer, N. Barnes, L. Carboni, 2016 .

Increased exploratory activity of APP23 mice in a novel environment is reversed by siRNA

P. Kelly, F. Natt, M. Staufenbiel, 2008, Brain Research.

Orexin 2 receptor antagonism sex‐dependently improves sleep/wakefulness and cognitive performance in tau transgenic mice

David K. Wright, Jeremy A. Metha, D. Hoyer, 2023, British journal of pharmacology.