A. Pautsch

发表

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

S. Rasmussen, Brian T DeVree, T. S. Kobilka, 2010, Nature.

Structure of the outer membrane protein A transmembrane domain

G. Schulz, A. Pautsch, 1998, Nature Structural Biology.

High-resolution structure of the OmpA membrane domain.

G. Schulz, A. Pautsch, G E Schulz, 2000, Journal of molecular biology.

Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis

Alexander Pautsch, Gisela Schnapp, A. Pautsch, 2015, European Respiratory Journal.

Crystal structure of glucokinase regulatory protein.

A. Pautsch, H. Nar, S. Kauschke, 2013, Biochemistry.

Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism

A. Pautsch, H. Brandstetter, G. Schnapp, 2022, ACS chemical biology.

Nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X‐ray crystallography

P Schelling, A Prota, G Folkers, 2000, Proteins.

Crystal structure of the Clostridium limosum C3 exoenzyme

A. Pautsch, C. Herrmann, K. Aktories, 2008, FEBS letters.

Inhibiteurs de la PI3 kinase

A. Pautsch, F. Kalkbrenner, Steffen Breitfelder, 2005 .

Covalent inhibitor reactivity prediction by the electrophilicity index—in and out of scope

Alexander Weber, A. Pautsch, C. Tautermann, 2020, Journal of Computer-Aided Molecular Design.

PolyQ expansion does not alter the Huntingtin-HAP40 complex

W. Baumeister, A. Pautsch, S. Kochanek, 2021, bioRxiv.

Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy

S. T. A. Shah, M. Caffrey, A. Pautsch, 2014, Crystal growth & design.

Fast native-SAD phasing for routine macromolecular structure determination

Ezequiel Panepucci, Meitian Wang, Oliver Weichenrieder, 2014, Nature Methods.

Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists.

R. Cheng, A. Pautsch, C. Tautermann, 2019, Structure.

Crystal structure of bisphosphorylated IGF-1 receptor kinase: insight into domain movements upon kinase activation.

A. Pautsch, H. Ahorn, H. Nar, 2001, Structure.

The cryo-electron microscopy structure of huntingtin

Stefan Kochanek, Wolfgang Baumeister, Qiang Guo, 2018, Nature.

A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems.

Alexander Pautsch, Volker Dötsch, Gisela Schnapp, 2012, Protein expression and purification.

Crystal structure of the C3bot–RalA complex reveals a novel type of action of a bacterial exoenzyme

A. Pautsch, C. Herrmann, K. Aktories, 2005, The EMBO journal.

Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib.

Alexander Pautsch, Stefan Knapp, Roman Fischer, 2016, ACS chemical biology.

High-Throughput Crystallography and Its Applications in Drug Discovery

Alexander Pautsch, Herbert Nar, D. Fiegen, 2017 .

Discovery and Development of Nintedanib: A Novel Antiangiogenic and Antifibrotic Agent

R. Kaiser, A. Pautsch, F. Hilberg, 2016 .

Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex.

W. Baumeister, A. Pautsch, S. Kochanek, 2021, Structure.

C3 exoenzymes, novel insights into structure and action of Rho-ADP-ribosylating toxins

A. Pautsch, K. Aktories, M. Vogelsgesang, 2007, Naunyn-Schmiedeberg's Archives of Pharmacology.

Strategy for membrane protein crystallization exemplified with OmpA and OmpX

G. Schulz, A. Pautsch, C. Siebold, 1999, Proteins.

Molecular Recognition of the Protein Phosphatase 1 Glycogen Targeting Subunit by Glycogen Phosphorylase*

A. Pautsch, R. Streicher, N. Stadler, 2008, Journal of Biological Chemistry.

BIreactive: A Machine-Learning Model to Estimate Covalent Warhead Reactivity

Alexander Weber, Ferruccio Palazzesi, Marc A Grundl, 2020, J. Chem. Inf. Model..

A Fast Ab Initio Predictor Tool for Covalent Reactivity Estimation of Acrylamides

Ferruccio Palazzesi, Marc A Grundl, Alexander Pautsch, 2019, J. Chem. Inf. Model..

The Implication of the First Agonist Bound Activated GPCR X-ray Structure on GPCR in Silico Modeling.

Alexander Pautsch, Christofer S Tautermann, A. Pautsch, 2011, ACS medicinal chemistry letters.

CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812

A. Pautsch, C. Tautermann, Anna-Katharina Apel, 2019 .

Corrigendum: Fast native-SAD phasing for routine macromolecular structure determination

J. Rose, M. Steinmetz, M. Caffrey, 2015, Nature Methods.

Structural basis of the mechanism and inhibition of a human ceramide synthase

A. Pautsch, C. Tautermann, E. Carpenter, 2023, bioRxiv.