V. Rao

发表

D. Oprian, V. Rao, 1996 .

Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.

David R. Anderson, S. Wright, V. Rao, 2017, Journal of medicinal chemistry.

Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling

V. Rao, E. Latz, S. Masters, 2018, The Journal of Biological Chemistry.

Interleukin 1 receptor–associated kinase 4 (IRAK4) plays a dual role in Myddosome formation and Toll-like receptor signalling

V. Rao, S. Masters, Katherine R. Balka, 2018 .

The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and Toll-like receptor agonists

P. Cohen, N. Gray, Tinghu Zhang, 2017, The Biochemical journal.

Interleukin 1/Toll-like Receptor-induced Autophosphorylation Activates Interleukin 1 Receptor-associated Kinase 4 and Controls Cytokine Induction in a Cell Type-specific Manner

J. Casanova, C. Picard, V. Rao, 2014, The Journal of Biological Chemistry.

Manner Controls Cytokine Induction in a Cell 1 Receptor-associated Kinase 4 and Autophosphorylation Activates Interleukin Interleukin 1 / Toll-like Receptor-induced Immunology :

J. Casanova, C. Picard, V. Rao, 2014 .

Expression Cloning of Protein Targets for 3-Phosphorylated Phosphoinositides*

G. Prestwich, Junying Yuan, V. Rao, 1999, The Journal of Biological Chemistry.

NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach.

V. Rao, Lih-Ling Lin, Y. Qiu, 2004, The Journal of biological chemistry.

hKSR-2 inhibits MEKK3-activated MAP kinase and NF-κB pathways in inflammation

V. Rao, Y. Zhang, Lih-Ling Lin, 2005 .

hKSR-2 inhibits MEKK3-activated MAP kinase and NF-kappaB pathways in inflammation.

V. Rao, Y. Zhang, Lih-Ling Lin, 2005, Biochemical and biophysical research communications.

Characterization of rhodopsin congenital night blindness mutant T94I.

D. Oprian, V. Rao, A. K. Gross, 2003, Biochemistry.

Activating mutations of rhodopsin and other G protein-coupled receptors.

D. Oprian, V. Rao, D. Oprian, 1996, Annual Review of Biophysics and Biomolecular Structure.

Mechanism of dysfunction of human variants of the IRAK4 kinase and a role for its kinase activity in interleukin-1 receptor signaling

J. Casanova, V. Rao, A. Puel, 2018, The Journal of Biological Chemistry.

The Interleukin‐1 Receptor–Associated Kinase 4 Inhibitor PF‐06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial

V. Pascual, V. Rao, M. Hegen, 2021, Arthritis & rheumatology.

NMDA and AMPA receptors: old channels, new tricks

Steven Finkbeiner, S. Finkbeiner, V. Rao, 2007, Trends in Neurosciences.

Splice Variants of the NR1 Subunit Differentially Induce NMDA Receptor-Dependent Gene Expression

S. Finkbeiner, V. Rao, Jun Wang, 2006, The Journal of Neuroscience.

SpliceVariantsoftheNR1SubunitDifferentiallyInduce NMDAReceptor-DependentGeneExpression

Sarah L Carter, V. Rao, 2006 .

AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc

S. Finkbeiner, V. Rao, J. Chin, 2006, Nature Neuroscience.

Heterozygous missense mutation in the rhodopsin gene as a cause of congenital stationary night blindness

D. Oprian, T. Dryja, E. Berson, 1993, Nature Genetics.

Epidermal Growth Factor Receptor-Dependent Regulation of Integrin-Mediated Signaling and Cell Cycle Entry in Epithelial Cells

V. Rao, S. Moores, J. Brugge, 2004, Molecular and Cellular Biology.

Entry in Epithelial Cells Integrin-Mediated Signaling and Cell Cycle Receptor-Dependent Regulation of Epidermal Growth Factor

Cindy., V. Rao, S. Moores, 2004 .

IRAK4 kinase activity controls Toll-like receptor–induced inflammation through the transcription factor IRF5 in primary human monocytes

V. Rao, R. Hawtin, Lih-Ling Lin, 2017, The Journal of Biological Chemistry.

Proteomic characterization of the dynamic KSR-2 interactome, a signaling scaffold complex in MAPK pathway.

V. Rao, Lih-Ling Lin, Y. Qiu, 2009, Biochimica et biophysica acta.

The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor

Junying Yuan, Or Gozani, Gerhard Wagner, 2003, Cell.

Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness

D. Oprian, V. Rao, G. B. Cohen, 1994, Nature.

Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice

P. Cohen, V. Rao, J. Arthur, 2019, Life Science Alliance.

Prevention and partial reversion of the lupus phenotype in ABIN1[D485N] mice by an IRAK4 inhibitor

Philip R. Cohen, V. Rao, C. Scudamore, 2021, Lupus Science & Medicine.

Characterization of (2R, 3S)-2-([[4-(2-butynyloxy)phenyl]sulfonyl]amino)-N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-alpha converting enzyme.

V. Rao, M. Hegen, J. Levin, 2004, International immunopharmacology.

Identification and optimization of indolo[2,3-c]quinoline inhibitors of IRAK4.

D. Boschelli, V. Rao, E. A. Murphy, 2014, Bioorganic & medicinal chemistry letters.

Protein Kinase D1 Regulates Synaptic Plasticity, Presenting a Novel Therapeutic Target for Neurological Disease.

S. Finkbeiner, V. Rao, Eva Ladow, 2013 .

Interleukin 1 receptor–associated kinase 4 (IRAK4) plays a dual role in Myddosome formation and Toll-like receptor signalling

V. Rao, S. Masters, D. Nardo, 2018 .