A. Hinney

发表

J. Hebebrand, A. Hinney, 2009, Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie.

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Tanya M. Teslovich, Ayellet V. Segrè, P. Elliott, 2010 .

A Common Genetic Variant Is Associated with Adult and Childhood Obesity

F. Hu, N. Laird, J. Hirschhorn, 2006, Science.

Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach

J. Nigg, S. Faraone, S. McWeeney, 2016, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Lack of Support for the Association between GAD2 Polymorphisms and Severe Human Obesity

P. Kwok, L. Pennacchio, W. Rief, 2005, PLoS biology.

Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index

Henrik, Tanya M. Teslovich, Jennie, 2012 .

A genome-wide association study of anorexia nervosa

I. Ntalla, E. Zeggini, D. Pinto, 2011, Molecular Psychiatry.

Epidemic obesity: are genetic factors involved via increased rates of assortative mating?

J. Hebebrand, A. Hinney, H. Remschmidt, 2000, International Journal of Obesity.

DCLK1 Variants Are Associated across Schizophrenia and Attention Deficit/Hyperactivity Disorder

Ole A. Andreassen, Vidar M. Steen, Manuel Mattheisen, 2012, PloS one.

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Subhajyoti De, Inês Barroso, Philippe Froguel, 2008, Nature Genetics.

Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups

Raimund Erbel, Barbara Heude, Mark I. McCarthy, 2010, PLoS genetics.

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Christian Gieger, Jianxin Shi, Inês Barroso, 2013, Nature Genetics.

The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study

J. Hebebrand, A. Hinney, J. Antel, 2020, Frontiers in Genetics.

Mutation screen of the brain derived neurotrophic factor gene (BDNF): Identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention‐deficit/hyperactivity disorder

B. Herpertz-Dahlmann, K. Konrad, J. Hebebrand, 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa

E. Zeggini, K. Stirrups, D. Collier, 2017, Molecular Psychiatry.

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

Hunna J. Watson, I. Ntalla, E. Zeggini, 2018, bioRxiv.

University of Groningen Investigation of common , low-frequency and rare genome-wide variation in anorexia nervosa Kas

E. Zeggini, K. Stirrups, D. Collier, 2017 .

Alterations in B cell subsets correlate with body composition parameters in female adolescents with anorexia nervosa

V. Arolt, U. Dannlowski, B. Baune, 2021, Scientific reports.

Correction: Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

C. Gieger, F. Kronenberg, A. Peters, 2008, PLoS ONE.

Synaptic processes and immune-related pathways implicated in Tourette syndrome

N. Freimer, M. Nöthen, B. Leventhal, 2020, Translational Psychiatry.

Synaptic processes and immune-related pathways implicated in Tourette syndrome

N. Freimer, M. Nöthen, B. Leventhal, 2020, Translational Psychiatry.

Bipolar disorder risk alleles in children with ADHD

S. Cichon, K. Lesch, S. Schreiber, 2013, Journal of Neural Transmission.

Further lack of association between the 5-HT2A gene promoter polymorphism and susceptibility to eating disorders and a meta-analysis pertaining to anorexia nervosa

B. Herpertz-Dahlmann, J. Hebebrand, A. Hinney, 1999, Molecular Psychiatry.

A Heterozygous Mutation in the Third Transmembrane Domain Causes a Dominant-Negative Effect on Signalling Capability of the MC4R

J. Hebebrand, A. Hinney, K. Widhalm, 2008, Obesity Facts.

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Hunna J. Watson, I. Ntalla, E. Zeggini, 2019, Nature Genetics.

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2017, Scientific Reports.

Comparison of metabolic profiles of acutely ill and short-term weight recovered patients with anorexia nervosa reveals alterations of 33 out of 163 metabolites.

T. Illig, B. Herpertz-Dahlmann, K. Suhre, 2012, Journal of psychiatric research.

Indications for Potential Parent-of-Origin Effects within the FTO Gene

P. Stadler, M. Stumvoll, M. Scholz, 2015, PloS one.

Case-control genome-wide association study of persistent attention-deficit hyperactivity disorder identifies FBXO33 as a novel susceptibility gene for the disorder.

L. Kiemeney, B. Franke, K. Lesch, 2015, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

Assessing causal links between metabolic traits, inflammation and schizophrenia: a univariable and multivariable, bidirectional Mendelian-randomization study

W. Cahn, R. Adan, J. Hebebrand, 2019, International journal of epidemiology.

Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants

H. Wichmann, T. Illig, H. Grallert, 2012, BMC Medical Genomics.

Aggravating effect of INSIG2 and FTO on overweight reduction in a one-year lifestyle intervention

J. Hebebrand, A. Hinney, T. Reinehr, 2009, Archives of Disease in Childhood.

Sympathetic function in human carriers of melanocortin-4 receptor gene mutations.

J. Hebebrand, A. Hinney, H. Lehnert, 2010, The Journal of clinical endocrinology and metabolism.

Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes.

J. Hebebrand, A. Hinney, H. Remschmidt, 1998, The Journal of clinical endocrinology and metabolism.

Association of the rs10830963 Polymorphism in MTNR1B with Fasting Glucose Levels in Chinese Children and Adolescents

J. Hebebrand, A. Hinney, Jun Ma, 2011, Obesity Facts.

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

E. Zeggini, D. Collier, H. Hakonarson, 2017, Molecular Psychiatry.

Is Information on Genetic Determinants of Obesity Helpful or Harmful for Obese People?—A Randomized Clinical Trial

W. Rief, J. Hebebrand, A. Hinney, 2007, Journal of General Internal Medicine.

Relationship between MTNR1B (melatonin receptor 1B gene) polymorphism rs10830963 and glucose levels in overweight children and adolescents †

M. Kleber, J. Hebebrand, A. Hinney, 2011, Pediatric diabetes.

PTBP2 – a gene with relevance for both Anorexia nervosa and body weight regulation

S. Ehrlich, B. Herpertz-Dahlmann, J. Hebebrand, 2022, Translational Psychiatry.

Causal Effect of Age at Menarche on the Risk for Depression: Results From a Two-Sample Multivariable Mendelian Randomization Study

J. Hebebrand, A. Hinney, C. Grasemann, 2022, Frontiers in Genetics.

pathway in eating disorders

J. González, X. Estivill, G. Escaramís, 2008 .

Meta-analysis on the effect of the N363S polymorphism of the glucocorticoid receptor gene (GRL) on human obesity

A. Martí, J. Martínez, J. Hebebrand, 2006, BMC Medical Genetics.

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

J. Gulcher, U. Thorsteinsdóttir, A. Kong, 2007, Nature Genetics.

obesity in melanocortin-4 receptor knockout mice Hyperphagia, not hypometabolism, causes early onset

T. Trouard, R. Cone, A. Hinney, 2015 .

Rescue of Melanocortin 4 Receptor (MC4R) Nonsense Mutations by Aminoglycoside‐Mediated Read‐Through

J. Hebebrand, A. Hinney, A. Grüters, 2012, Obesity.

A NOVEL MUTATION Thr 162 Arg OF THE MELANOCORTIN 4 RECEPTOR GENE IN A SPANISH CHILDREN AND ADOLESCENTS POPULATION

A. Martí, J. Hebebrand, A. Hinney, 2010 .

A novel mutation Thr162Arg of the melanocortin 4 receptor gene in a Spanish children and adolescent population

A. Martí, J. Martínez, J. Hebebrand, 2007, Clinical endocrinology.

Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia

J. Hebebrand, A. Hinney, A. Scherag, 2008, BMC Cancer.

Several mutations in the melanocortin 4 receptor gene are associated with obesity in Chinese children and adolescents

J. Hebebrand, A. Hinney, L. Liang, 2006, Journal of endocrinological investigation.

Hyperphagia, not hypometabolism, causes early onset obesity in melanocortin-4 receptor knockout mice.

A. Hinney, N. Christ, K. Moar, 2003, Physiological genomics.

Dysfunctionof lipid sensorGPR120 leads to obesity in both mouse and human

M. Jarvelin, F. Horber, B. Balkau, 2020 .

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

P. Elliott, M. Jarvelin, F. Horber, 2012, Nature.

Glucose transporter 4 gene: association studies pertaining to alleles of two polymorphisms in extremely obese children and adolescents and in normal and underweight controls.

W. Grassl, J. Hebebrand, A. Hinney, 2002, Annals of the New York Academy of Sciences.

Detailed stratified GWAS analysis for severe COVID-19 in four European populations

Francisco J. Medrano, S. Brunak, V. Moreno, 2022, Human molecular genetics.

Missense variants in the human peroxisome proliferator-activated receptor-gamma2 gene in lean and obese subjects.

H. Münzberg, J. Hebebrand, A. Hinney, 1999, European journal of endocrinology.

Will leptin provide an insight into weight regulation of patients with anorexia nervosa

J. Hebebrand, A. Hinney, H. Remschmidt, 1997 .

The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits

A. Hinney, P. Fischer-Posovszky, A. Körner, 2022, Nature Reviews Endocrinology.

Lack of association between the –759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals

J. Hebebrand, A. Hinney, H. Remschmidt, 2004, Psychiatric genetics.

A role for β-melanocyte-stimulating hormone in human body-weight regulation

M. Tschöp, J. Hebebrand, A. Hinney, 2006 .

expression in brown and white adipocytes in rat pups Mechanisms for LEPR-mediated regulation of leptin

L. Weissfeld, A. Hinney, N. Christ, 2015 .

Successful Treatment with Atomoxetine of an Adolescent Boy with Attention Deficit/Hyperactivity Disorder, Extreme Obesity, and Reduced Melanocortin 4 Receptor Function

J. Hebebrand, A. Hinney, Ö. Albayrak, 2013, Obesity Facts.

Rapid amelioration of anorexia nervosa in a male adolescent during metreleptin treatment including recovery from hypogonadotropic hypogonadism

J. Hebebrand, A. Hinney, N. Barth, 2021, European Child & Adolescent Psychiatry.

Lack of Association of CD36 SNPs With Early Onset Obesity: A Meta‐Analysis in 9,973 European Subjects

M. Jarvelin, B. Balkau, D. Meyre, 2011, Obesity.

A role for b-melanocyte-stimulating hormone in human bodyweight regulation

M. Tschöp, J. Hebebrand, A. Hinney, 2022 .

Analysis of the uncoupling protein-1 (UCP1) gene in obese and lean subjects: Identification of four amino acid variants

H. Münzberg, J. Hebebrand, A. Hinney, 1998, International Journal of Obesity.

A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder

J. Hebebrand, A. Hinney, J. Antel, 2020, European Journal of Nutrition.

A novel non-synonymous mutation in the melanocortin-4 receptor gene (MC4R) in a 2-year-old Austrian girl with extreme obesity.

D. Prayer, J. Hebebrand, A. Hinney, 2007, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Evidence for correlations between BMI-associated SNPs and circRNAs

C. Dieterich, J. Hebebrand, A. Hinney, 2022, Scientific Reports.

Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity.

K. Clément, J. Kere, A. Hamsten, 2011, The Journal of clinical endocrinology and metabolism.

Effect of vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients: results of a randomized controlled trial

J. Hebebrand, A. Hinney, D. Führer, 2020, European Journal of Nutrition.

The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits

A. Hinney, P. Fischer-Posovszky, A. Körner, 2022, Nature Reviews Endocrinology.

Absence of leptin deficiency mutation in extremely obese German children and adolescents

J. Hebebrand, A. Hinney, H. Remschmidt, 1997, International Journal of Obesity.

Selection of unrelated bone marrow donors by PCR-SSP typing and subsequent nonradioactive sequence-based typing for HLA DRB1/3/4/5, DQB1, and DPB1 alleles.

P. Wernet, A. Hinney, M. Uhrberg, 1994, Tissue antigens.

Analysis of the HLA‐DR gene locus by temperature gradient gel electrophoresis and its application for the rapid selection of unrelated bone marrow donors

P. Wernet, A. Hinney, M. Uhrberg, 1994, Electrophoresis.

Genome-wide analysis of rare copy number variations reveals PARK2 as a candidate gene for attention-deﬁcit/hyperactivity disorder

S. Cichon, H. Wichmann, K. Jöckel, 2013 .

A genome-wide association meta-analysis identifies new childhood obesity loci

Inês Barroso, Mark I. McCarthy, Philippe Froguel, 2012, Nature Genetics.

Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin.

T. Illig, H. Grallert, J. Hebebrand, 2010, European journal of endocrinology.

Expression of CXCR4 on CD4+ T cells predicts body composition parameters in female adolescents with anorexia nervosa

V. Arolt, U. Dannlowski, B. Baune, 2022, Frontiers in Psychiatry.

Association of the melanocortin 4 receptor with feed intake and daily gain in F2 Mangalitsa x Piétrain pigs.

J. Hebebrand, A. Hinney, H. Remschmidt, 2006, Animal genetics.

Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders

M. Gratacós, X. Estivill, S. Ehrlich, 2009, Pharmacogenetics and genomics.

Genetic studies of antithrombin III with IEF and ASO hybridization

A. Hinney, H. Ritter, C. Luckenbach, 1992, Human Genetics.

List of Contributors

R. Dalle Grave, B. Herpertz-Dahlmann, E. Stice, 2019, Eating Disorders and Obesity in Children and Adolescents.

DCLK1Variants Are Associated across Schizophrenia and Attention Deficit/Hyperactivity Disorder

Thomas W. Mühleisen, S. Cichon, T. Mühleisen, 2022 .

Subjective reward processing and catechol-O- methyltransferase Val158Met polymorphism as potential research domain criteria in addiction: A pilot study

I. Tendolkar, A. Hinney, U. Bonnet, 2022, Frontiers in Psychiatry.

Significant association between a silent polymorphism in the neuromedin B gene and body weight in German children and adolescents

K. Grzeschik, J. Hebebrand, A. Hinney, 2000, Acta Diabetologica.

The Fatty Acid Amide Hydrolase (FAAH) Gene Variant rs324420 AA/AC is not Associated with Weight Loss in a 1-Year Lifestyle Intervention for Obese Children and Adolescents

M. Kleber, J. Hebebrand, A. Hinney, 2011, Hormone and Metabolic Research.

Identification of a deletion variant in the gene encoding the human alpha(2A)-adrenergic receptor.

H. Münzberg, J. Hebebrand, A. Hinney, 2001, European journal of endocrinology.

Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease.

C. Gieger, F. Kronenberg, A. Peters, 2010, Atherosclerosis.

Systematic screening for mutations in the human necdin gene (NDN): identification of two naturally occurring polymorphisms and association analysis in body weight regulation

K. Grzeschik, J. Hebebrand, A. Hinney, 2001, International Journal of Obesity.

Abstract 1879: Genetic Variation at Chromosome 1p13.3 Affects Sortilin mRNA Expression, Cellular LDL Uptake and Serum LDL Levels Which Translates to the Risk of Coronary Artery Disease

C. Gieger, F. Kronenberg, A. Peters, 2009 .

Changes of peripheral alpha-melanocyte-stimulating hormone in childhood obesity.

J. Hebebrand, A. Hinney, T. Reinehr, 2010, Metabolism: clinical and experimental.

Association of the MC4R V103I Polymorphism With Obesity: A Chinese Case–control Study and Meta‐analysis in 55,195 Individuals

J. Hebebrand, A. Hinney, Jun Ma, 2010, Obesity.

A role for beta-melanocyte-stimulating hormone in human body-weight regulation.

A. von Deimling, M. Tschöp, J. Hebebrand, 2006, Cell metabolism.

Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene.

J. Hebebrand, A. Hinney, H. Remschmidt, 1999, American journal of human genetics.

Decreased melanocortin‐4 receptor function conferred by an infrequent variant at the human melanocortin receptor accessory protein 2 gene

J. Hebebrand, A. Hinney, H. Biebermann, 2016, Obesity.

The adrenal steroid profile in adolescent depression: a valuable bio-readout?

J. Hebebrand, A. Hinney, C. Grasemann, 2022, Translational Psychiatry.

22nd European Congress on Obesity (ECO2015), Prague, Czech Republic, May 6-9, 2015: Abstracts

J. N. Fidalgo, Jimmy D Bell, L. S. Silveira, 2015, Obesity Facts.

Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

C. Gieger, F. Kronenberg, A. Peters, 2008, PloS one.

New susceptibility loci for severe COVID-19 by detailed GWAS analysis in European populations

M. Nöthen, S. Brunak, V. Moreno, 2021, medRxiv.

Genetic variation at the CELF1 (CUGBP, elav‐like family member 1 gene) locus is genome‐wide associated with Alzheimer's disease and obesity

I. Heid, D. Harold, R. Sims, 2014, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genetic predisposition to obesity in bulimia nervosa: a mutation screen of the melanocortin-4 receptor gene

J. Hebebrand, A. Hinney, H. Remschmidt, 2002, Molecular Psychiatry.

The 5-HT transporter gene-linked polymorphic region (5-HTTLPR) in evolutionary perspective: Alternative biallelic variation in rhesus monkeys

Annemarie Poustka, Johannes Hebebrand, Klaus-Peter Lesch, 2005, Journal of Neural Transmission.

An instance of clinical radiation morbidity and cellular radiosensitivity, not associated with ataxia-telangiectasia.

A. Hinney, C. Arlett, B. Bridges, 1990, The British journal of radiology.

Meta‐analysis of genome‐wide linkage scans of attention deficit hyperactivity disorder

B. Franke, M. Gill, C. Freitag, 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

Hunna J. Watson, Ryan L. Collins, Dan J Stein, 2019, bioRxiv.

Increased constraints on MC4R during primate and human evolution

M. Stoneking, J. Hebebrand, A. Hinney, 2008, Human Genetics.

Common obesity risk alleles in childhood attention‐deficit/hyperactivity disorder

S. Cichon, M. Nöthen, B. Neale, 2013, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Hunna J. Watson, I. Ntalla, E. Zeggini, 2019, Nature Genetics.

Genome‐wide association study in German patients with attention deficit/hyperactivity disorder

S. Cichon, B. Franke, C. Freitag, 2011, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders.

J. González, M. Gratacós, X. Estivill, 2008, Human molecular genetics.

Family-based association study of serotonergic candidate genes and attention-deficit/hyperactivity disorder in a German sample

B. Herpertz-Dahlmann, K. Konrad, J. Hebebrand, 2006, Journal of Neural Transmission.

Prevalence estimates of putatively pathogenic leptin variants in the gnomAD database

J. Hebebrand, A. Hinney, P. Fischer-Posovszky, 2022, bioRxiv.

www.ssoar.info From monogenic to polygenic obesity: recent advances

J. Hebebrand, A. Hinney, C. Vogel, 2021 .

Estimated prevalence of potentially damaging variants in the leptin gene

A. Hinney, P. Fischer-Posovszky, M. Wabitsch, 2017, Molecular and Cellular Pediatrics.

Genes and the hypothalamic control of metabolism in humans.

A. Hinney, J. Antel, A. Volckmar, 2014, Best practice & research. Clinical endocrinology & metabolism.

Molecular genetic aspects of weight regulation.

J. Hebebrand, A. Hinney, A. Scherag, 2013, Deutsches Arzteblatt international.

Chipping Away the ‘Missing Heritability’: GIANT Steps Forward in the Molecular Elucidation of Obesity – but Still Lots to Go

J. Hebebrand, A. Hinney, A. Volckmar, 2010, Obesity Facts.

From monogenic to polygenic obesity: recent advances

J. Hebebrand, A. Hinney, C. Vogel, 2010, European Child & Adolescent Psychiatry.

Environmental and genetic risk factors in obesity.

J. Hebebrand, A. Hinney, 2009, Child and adolescent psychiatric clinics of North America.

Analysis of sequence variations in the suppressor of cytokine signaling (SOCS)-3 gene in extremely obese children and adolescents

J. Hebebrand, A. Hinney, A. Scherag, 2007, BMC Medical Genetics.

Genetic Factors for Overweight and CAD

J. Erdmann, J. Hebebrand, A. Hinney, 2006, Herz Kardiovaskuläre Erkrankungen.

Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory Title Lack of Support for the Association Between GAD 2 Polymorphisms and Severe Human Obesity Permalink

P. Kwok, L. Pennacchio, W. Rief, 2005 .

Perspectives: molecular genetic research in human obesity

J. Hebebrand, A. Hinney, F. Geller, 2003, Obesity reviews : an official journal of the International Association for the Study of Obesity.

Genome scan for childhood and adolescent obesity in German families.

J. Hebebrand, A. Hinney, H. Remschmidt, 2003, Pediatrics.

The genetics of obesity: practical implications

J. Hebebrand, A. Hinney, F. Geller, 2001, International Journal of Obesity.

Candidate gene polymorphisms in eating disorders.

J. Hebebrand, A. Hinney, H. Remschmidt, 2000, European journal of pharmacology.

No evidence for involvement of the leptin gene in anorexia nervosa, bulimia nervosa, underweight or early onset extreme obesity: identification of two novel mutations in the coding sequence and a novel polymorphism in the leptin gene linked upstream region

F. Poustka, B. Herpertz-Dahlmann, J. Hebebrand, 1998, Molecular Psychiatry.

Transmission disequilibrium and sequence variants at the leptin receptor gene in extremely obese German children and adolescents

K. Grzeschik, J. Hebebrand, A. Hinney, 1998, Human Genetics.

Serotonin transporter gene-linked polymorphic region: allele distributions in relationship to body weight and in anorexia nervosa.

F. Poustka, K. Lesch, K. Grzeschik, 1997, Life sciences.

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

Alicia R. Martin, N. Eriksson, N. Wray, 2017, Biological Psychiatry.

The involvement of the canonical Wnt‐signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta‐analysis

K. Lesch, J. Hebebrand, A. Hinney, 2018, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

No evidence for intervention-associated DNA methylation changes in monocytes of patients with posttraumatic stress disorder or anorexia nervosa

H. Kessler, J. Hebebrand, A. Hinney, 2020, medRxiv.

Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa.

Raymond Walters, Stephan Ripke, Gerome Breen, 2017, The American journal of psychiatry.

A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity.

Christopher D. Brown, A. Uitterlinden, M. McCarthy, 2019, Human molecular genetics.

Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.

M. Fornage, M. McCarthy, H. Hakonarson, 2015, Human molecular genetics.

Melanocortin-4 receptor in energy homeostasis and obesity pathogenesis.

A. Hinney, A. Volckmar, N. Knoll, 2013, Progress in molecular biology and translational science.

Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany.

T. Meitinger, M. Platzer, T. Illig, 2006, The Journal of clinical endocrinology and metabolism.

Association of the 103I MC4R allele with decreased body mass in 7937 participants of two population based surveys

F. Kronenberg, A. Döring, T. Illig, 2005, Journal of Medical Genetics.

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity.

T. Gudermann, M. Platzer, T. Illig, 2004, American journal of human genetics.

Ghrelin receptor gene: identification of several sequence variants in extremely obese children and adolescents, healthy normal-weight and underweight students, and children with short normal stature.

K. Huse, T. Meitinger, P. Lichtner, 2004, The Journal of clinical endocrinology and metabolism.

Ghrelin gene: identification of missense variants and a frameshift mutation in extremely obese children and adolescents and healthy normal weight students.

J. Hebebrand, A. Hinney, H. Remschmidt, 2002, The Journal of clinical endocrinology and metabolism.

Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans.

J. Hebebrand, A. Hinney, H. Remschmidt, 1999, The Journal of clinical endocrinology and metabolism.

Common variants at 6q22 and 17q21 are associated with intracranial volume

Wiro J Niessen, Clifford R Jack, Reinhold Schmidt, 2012, Nature Genetics.

Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.

H. Stefánsson, N. Freimer, R. Ophoff, 2019, The American journal of psychiatry.

Mapping the human genetic architecture of COVID-19

Mattia G. Bergomi, Christopher M. DeBoever, Matthew A. Wiles, 2021, Nature.

Genetic evidence of assortative mating in humans

Tanya M. Teslovich, Ross M. Fraser, Brendan P. Zietsch, 2017, Nature Human Behaviour.

Increased constraints on MC4R during primate and human evolution

M. Stoneking, J. Hebebrand, A. Hinney, 2008, Human Genetics.

Successful methylphenidate treatment of early onset extreme obesity in a child with a melanocortin-4 receptor gene mutation and attention deficit/hyperactivity disorder.

J. Hebebrand, A. Hinney, S. Scherag, 2011, European journal of pharmacology.

The Association of a SNP Upstream of INSIG2 with Body Mass Index is Reproduced in Several but Not All Cohorts

Xiaofeng Zhu, Thomas Meitinger, Christoph Lange, 2007, PLoS genetics.

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2017, Scientific Reports.

β3-adrenergic-receptor allele distributions in children, adolescents and young adults with obesity, underweight or anorexia nervosa

F. Poustka, K. Grzeschik, J. Hebebrand, 1997, International Journal of Obesity.

Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations

Hunna J. Watson, I. Ntalla, E. Zeggini, 2016, bioRxiv.

Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing

S. Haas, H. Grallert, J. Hebebrand, 2016, PloS one.

Fine Mapping of a GWAS-Derived Obesity Candidate Region on Chromosome 16p11.2

T. Illig, H. Grallert, J. Hebebrand, 2015, PloS one.

Genome-wide analysis of rare copy number variations reveals PARK2 as a candidate gene for attention-deficit/hyperactivity disorder

S Cichon, S. Cichon, C. Freitag, 2012, Molecular Psychiatry.

Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p

Evan Z. Macosko, Jack M. Fu, Jessica B. Girault, 2022, Nature Genetics.

Child and adolescent psychiatric genetics

J. Hebebrand, A. Hinney, A. Scherag, 2010, European Child & Adolescent Psychiatry.

Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome

M. Daly, H. Stefánsson, R. Ophoff, 2022, Translational Psychiatry.

Genetic and epigenetic findings in anorexia nervosa

A. Hinney, Raphael Hirtz, R. Hirtz, 2020, Medizinische Genetik.

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

Hunna J. Watson, I. Ntalla, E. Zeggini, 2019, bioRxiv.

Genetics of Eating and Weight Disorders

A. Hinney, J. Giuranna, 2019, Eating Disorders and Obesity in Children and Adolescents.

The role of genetic variation of human metabolism for BMI, mental traits and mental disorders

I. König, I. Heid, R. Adan, 2018, Molecular metabolism.

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

E. Zeggini, D. Collier, H. Hakonarson, 2017, Molecular Psychiatry.

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

E. Zeggini, D. Collier, H. Hakonarson, 2017, Molecular Psychiatry.

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.

Thomas Gudermann, Helmut Remschmidt, Johannes Hebebrand, 2003, The Journal of clinical endocrinology and metabolism.

A Novel SP1/SP3 Dependent Intronic Enhancer Governing Transcription of the UCP3 Gene in Brown Adipocytes

H. Jarrett, A. Hinney, M. Klingenspor, 2013, PloS one.

Elevated Common Variant Genetic Risk for Tourette Syndrome in a Densely Affected Pedigree

Michael Okun, H. Stefánsson, R. Ophoff, 2021, Molecular Psychiatry.

Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies.

J. Hebebrand, A. Hinney, L. Gortner, 2006, Human molecular genetics.

Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations

D. Collier, M. Gratacós, X. Estivill, 2005, European Journal of Human Genetics.

Genetics of Eating Disorders

A. Hinney, A. Volckmar, 2013, Current Psychiatry Reports.

High-throughput DNA methylation analysis in anorexia nervosa confirms TNXB hypermethylation

E. Zeggini, D. Collier, T. Illig, 2018, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Genome Wide Association (GWA) Study for Early Onset Extreme Obesity Supports the Role of Fat Mass and Obesity Associated Gene (FTO) Variants

Harald Grallert, Thomas Illig, Winfried Rief, 2007, PloS one.

Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa

T. Meitinger, M. Platzer, B. Herpertz-Dahlmann, 2008, Child and adolescent psychiatry and mental health.

Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity

J. Hebebrand, A. Hinney, C. Grasemann, 2021, Frontiers in Psychiatry.

The 103I variant of the melanocortin 4 receptor is associated with low serum triglyceride levels.

J. Hebebrand, A. Hinney, F. Geller, 2006, The Journal of clinical endocrinology and metabolism.

Large quantitative effect of melanocortin-4 receptor gene mutations on body mass index

T. Gudermann, J. Hebebrand, A. Hinney, 2004, Journal of Medical Genetics.

Variants in the human β1‐,β2‐ and β3‐adrenergic receptor genes are not associated with morbid obesity in children and adolescents

J. Hebebrand, A. Hinney, A. Hamann, 2004 .

Gain‐of‐function variants in the melanocortin 4 receptor gene confer susceptibility to binge eating disorder in subjects with obesity: a systematic review and meta‐analysis

D. Meyre, J. Hebebrand, A. Hinney, 2018, Obesity reviews : an official journal of the International Association for the Study of Obesity.

Do Common Variants Separate between Obese Melanocortin-4 Receptor Gene Mutation Carriers and Non-Carriers? The Impact of Cryptic Relatedness

T. Illig, H. Grallert, J. Hebebrand, 2012, Hormone Research in Paediatrics.

Association of the MC4R V103I Polymorphism With the Metabolic Syndrome: The KORA Study

F. Kronenberg, H. Wichmann, D. Ankerst, 2008, Obesity.

Independent confirmation of a major locus for obesity on chromosome 10.

J. Hebebrand, A. Hinney, H. Remschmidt, 2000, The Journal of clinical endocrinology and metabolism.

Genetic findings in anorexia and bulimia nervosa.

J. Hebebrand, A. Hinney, S. Scherag, 2010, Progress in molecular biology and translational science.

Eating disorders: the current status of molecular genetic research

J. Hebebrand, A. Hinney, S. Scherag, 2009, European Child & Adolescent Psychiatry.

Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups

H. Völzke, H. Wichmann, D. Rosskopf, 2009, BMC Medical Genetics.

Association and Linkage Studies in Caucasians

J. Hebebrand, A. Hinney, 2007 .

Mutation screen and association studies in the Diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13

T. Meitinger, M. Platzer, J. Hebebrand, 2007, BMC Genetics.

Adiposity in the first half of life. Abstracts of the 27th Annual Meeting of the German Society for Obesity Research. October 6-8, 2011. Bochum, Germany.

Santiago de Compostela, J. Oppert, G. Chrousos, 2011, Obesity facts.

The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus

H. Grallert, J. Hebebrand, A. Hinney, 2018, Obesity Facts.

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis

André Scherag, Johannes Hebebrand, Helmut Schäfer, 2010, Human molecular genetics.

[Genetic determinants of obesity. Current issues].

J. Hebebrand, A. Hinney, K. Bammann, 2010, Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz.

Relevance of polymorphisms in MC4R and BDNF in short normal stature

S. Grant, J. Hebebrand, A. Hinney, 2018, BMC Pediatrics.

Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome: a systematic review and meta-analysis

M. McCarthy, K. Ewens, F. Grigorescu, 2012, Diabetologia.

Evaluation of the Obesity Genes FTO and MC4R and the Type 2 Diabetes Mellitus Gene TCF7L2 for Contribution to Stroke Risk: The Mannheim-Heidelberg Stroke Study

R. Dodel, J. Hebebrand, A. Hinney, 2011, Obesity Facts.

Common Variants Near MC4R: Exploring Gender Effects in Overweight and Obese Children and Adolescents Participating in a Lifestyle Intervention

J. Hebebrand, A. Hinney, A. Scherag, 2011, Obesity Facts.

Genetic Markers, Weight Reduction, and Behavioral Changes in Lifestyle

A. Hinney, T. Reinehr, 2011 .

Investigation of a Genome Wide Association Signal for Obesity: Synthetic Association and Haplotype Analyses at the Melanocortin 4 Receptor Gene Locus

J. Hebebrand, A. Hinney, A. Scherag, 2010, PloS one.

Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA

H. Wichmann, A. Döring, T. Illig, 2010, International Journal of Obesity.

Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS)

Harald Grallert, Thomas Illig, André Scherag, 2010, BMC Medical Genetics.

Three at One Swoop!

J. Hebebrand, A. Hinney, 2009, Obesity Facts.

Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry

Harald Grallert, Thomas Illig, Iris M Heid, 2009, BMC Medical Genetics.

The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals

S. O’Rahilly, E. Young, M. Sandhu, 2007, International Journal of Obesity.

Familiality and molecular genetics of attention networks in ADHD

B. Herpertz-Dahlmann, K. Konrad, J. Hebebrand, 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genetic aspects in attention-deficit/hyperactivity disorder

J. Hebebrand, A. Hinney, Ö. Albayrak, 2008, Journal of Neural Transmission.

Association and linkage of allelic variants of the dopamine transporter gene in ADHD

K. Lesch, N. Hübner, B. Herpertz-Dahlmann, 2007, Molecular Psychiatry.

A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs

K Konrad, A Dempfle, H Remschmidt, 2006, Molecular Psychiatry.

Association study in eating disorders: TPH2 associates with anorexia nervosa and self‐induced vomiting

D. Boomsma, R. Adan, S. Ehrlich, 2011, Genes, brain, and behavior.

Serotonin transporter gene polymorphism (5-HTTLPR), environmental conditions, and developing negative emotionality and fear in early childhood

J. Hebebrand, A. Hinney, S. Friedel, 2009, Journal of Neural Transmission.

No evidence for preferential transmission of common valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor gene (BDNF) in ADHD

C. Freitag, K. Lesch, B. Herpertz-Dahlmann, 2007, Journal of Neural Transmission.

Gene Set of Nuclear-Encoded Mitochondrial Regulators Is Enriched for Common Inherited Variation in Obesity

C. Gieger, A. Peters, H. Wichmann, 2013, PloS one.

Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa

E. Zeggini, P. Sullivan, J. González, 2017, Psychiatric genetics.

Common Genetic Variation and Age of Onset of Anorexia Nervosa

Hunna J. Watson, D. Pinto, S. Scherer, 2021, Biological Psychiatry Global Open Science.

TCF7L2 Polymorphism rs7903146 and Predisposition for Type 2 Diabetes Mellitus in Obese Children

J. Hebebrand, A. Hinney, T. Reinehr, 2008, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Definable somatic disorders in overweight children and adolescents.

J. Hebebrand, A. Hinney, T. Reinehr, 2007, The Journal of pediatrics.

Vitamin D and the Risk of Depression: A Causal Relationship? Findings from a Mendelian Randomization Study

I. König, J. Hebebrand, A. Hinney, 2019, Nutrients.

Effect of an vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients – a randomized controlled trial: study protocol

J. Hebebrand, A. Hinney, D. Führer, 2018, BMC Psychiatry.

Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humans

T. Meitinger, D. Meyre, P. Froguel, 2008, European Journal of Human Genetics.

Association analyses for dopamine receptor gene polymorphisms and weight status in a longitudinal analysis in obese children before and after lifestyle intervention

A. Hinney, T. Reinehr, C. Roth, 2013, BMC Pediatrics.

Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity.

P. Dominguez-Salas, A. Prentice, F. Heppner, 2016, Cell metabolism.

Systematic mutation screening of the estrogen receptor beta gene in probands of different weight extremes: identification of several genetic variants.

J. Hebebrand, A. Hinney, J. K. Young, 1998, The Journal of clinical endocrinology and metabolism.

Screening for mutations in the neuropeptide Y Y5 receptor gene in cohorts belonging to different weight extremes

F. Poustka, J. Hebebrand, A. Hinney, 1998, International Journal of Obesity.

Common variants at 6q22 and 17q21 are associated with intracranial volume

Reinhold Schmidt, Stefan Ropele, Sudha Seshadri, 2013, Nature Genetics.

Nonradioactive Approach to Type DNA by Minisatellite Variant Repeats

A. Hinney, H. Ritter, C. Luckenbach, 1994 .

Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?

J. Hebebrand, A. Hinney, V. Steen, 2009, Molecular Psychiatry.

Erratum: Common variants at 6q22 and 17q21 are associated with intracranial volume

M. Jarvelin, L. Coin, M. Fornage, 2013, Nature Genetics.

Genetic Sum Score of Risk Alleles Associated with Body- Mass-Index Interacts with Socioeconomic Status in the Heinz Nixdorf Recall Study

A. Hinney, 2019 .

Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?

F. Kronenberg, M. McCarthy, F. Hu, 2009, PLoS genetics.

Polygenic Obesity in Humans

J. Hebebrand, A. Hinney, 2008, Obesity Facts.

5-HT2A promoter polymorphism −1438G/A in children and adolescents with obsessive-compulsive disorders

B. Herpertz-Dahlmann, J. Hebebrand, A. Hinney, 2002, Molecular Psychiatry.

Association Studies on Ghrelin and Ghrelin Receptor Gene Polymorphisms With Obesity

B. Heude, D. Meyre, P. Froguel, 2009, Obesity.

Lack of Evidence for a Relationship Between the Hypothalamus-Pituitary-Adrenal and the Hypothalamus-Pituitary-Thyroid Axis in Adolescent Depression

J. Hebebrand, A. Hinney, C. Grasemann, 2021, Frontiers in Endocrinology.

Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase (GOAT) is associated with anorexia nervosa.

S. Ehrlich, B. Herpertz-Dahlmann, P. Pfluger, 2011, Journal of psychiatric research.

Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects

Alexander Koller, J. Hebebrand, A. Hinney, 2020, Translational Psychiatry.

Sex differences in anxiety and depression in children with attention deficit hyperactivity disorder: Investigating genetic liability and comorbidity

Henrik, B. Franke, K. Lesch, 2021 .

Mutation analysis of the MCHR1 gene in human obesity.

K. Huse, O. Pedersen, K. Clément, 2005, European journal of endocrinology.

Suggestive Evidence for Causal Effect of Leptin Levels on Risk for Anorexia Nervosa: Results of a Mendelian Randomization Study

J. Hebebrand, A. Hinney, J. Antel, 2021, Frontiers in Genetics.

The association of serum leptin levels with food addiction is moderated by weight status in adolescent psychiatric inpatients

J. Hebebrand, A. Hinney, S. Dickson, 2018, European eating disorders review : the journal of the Eating Disorders Association.

Association between an agouti-related protein gene polymorphism and anorexia nervosa

H Remschmidt, H. Engeland, R. Adan, 2001, Molecular Psychiatry.

5-HT2A receptor gene polymorphisms, anorexia nervosa, and obesity

M. Nöthen, J. Hebebrand, A. Hinney, 1997, The Lancet.

Transmission disequilibrium studies in children and adolescents with obsessive-compulsive disorders pertaining to polymorphisms of genes of the serotonergic pathway

B. Herpertz-Dahlmann, J. Hebebrand, A. Hinney, 2004, Journal of Neural Transmission.

No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents.

T. Meitinger, P. Lichtner, J. Hebebrand, 2007, Molecular genetics and metabolism.

Evaluation of a Cys23Ser mutation within the human 5-HT2C receptor gene: no evidence for an association of the mutant allele with obesity or underweight in children, adolescents and young adults.

K. Grzeschik, J. Hebebrand, A. Hinney, 1997, Life sciences.

No evidence for an involvement of alleles of polymorphisms in the serotonin1Dβ and 7 receptor genes in obesity, underweight or anorexia nervosa

F. Poustka, J. Hebebrand, A. Hinney, 1999, International Journal of Obesity.

Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity

T. Illig, H. Grallert, W. Rief, 2010, BMC Medical Genetics.

The 5-HT2A −1438G/A polymorphism in anorexia nervosa: a combined analysis of 316 trios from six European centres

H Remschmidt, D. Collier, M. Gratacós, 2001, Molecular Psychiatry.

No evidence for involvement of alleles of the 825-C/T polymorphism of the G-protein subunit beta 3 in body weight regulation.

J. Hebebrand, A. Hinney, H. Remschmidt, 2001, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Catechol-O-Methyltransferase Val158Met Polymorphism Is Associated with Somatosensory Amplification and Nocebo Responses

W. Rief, A. Hinney, H. Engler, 2014, PloS one.

Genetic Risk Factors in Eating Disorders

J. Hebebrand, A. Hinney, H. Remschmidt, 2004, American journal of pharmacogenomics : genomics-related research in drug development and clinical practice.

Estrogen Receptor 1 Gene (ESR1) is Associated with Restrictive Anorexia Nervosa

J. Guelfi, P. Gorwood, S. Ehrlich, 2010, Neuropsychopharmacology.

FTO Gene: Association to Weight Regain after Lifestyle Intervention in Overweight Children

A. Hinney, T. Reinehr, C. Roth, 2014, Hormone Research in Paediatrics.

Lifestyle Intervention in Obese Children With Variations in the Melanocortin 4 Receptor Gene

J. Hebebrand, A. Hinney, H. Biebermann, 2009, Obesity.

Evidence of an Influence of a Polymorphism Near the INSIG2 on Weight Loss During a Lifestyle Intervention in Obese Children and Adolescents

J. Hebebrand, A. Hinney, T. Reinehr, 2008, Diabetes.

Role of the neurotrophin network in eating disorders' subphenotypes: body mass index and age at onset of the disease.

J. González, M. Gratacós, X. Estivill, 2010, Journal of psychiatric research.

No Effect of Thyroid Dysfunction and Autoimmunity on Health-Related Quality of Life and Mental Health in Children and Adolescents: Results From a Nationwide Cross-Sectional Study

A. Hinney, C. Grasemann, B. Hauffa, 2020, Frontiers in Endocrinology.

Rapid amelioration of anorexia nervosa in a male adolescent during metreleptin treatment including recovery from hypogonadotropic hypogonadism

J. Hebebrand, A. Hinney, N. Barth, 2021, European Child & Adolescent Psychiatry.

Using ancestry-informative markers to identify fine structure across 15 populations of European origin

Graham M Lord, Günter P. Wagner, I. Ntalla, 2014, European Journal of Human Genetics.

Glucose Transporter 4 Gene

W. Grassl, J. Hebebrand, A. Hinney, 2002 .

Exploring the genetic link between RLS and ADHD.

K. Lesch, K. Konrad, J. Hebebrand, 2009, Journal of psychiatric research.

Food Addiction in Gambling Disorder: Frequency and Clinical Outcomes

A. Hinney, F. Casanueva, J. Menchón, 2017, Front. Psychol..

Klotho KL-VS haplotype does not improve cognition in a population-based sample of adults age 55–87 years

A. Stang, B. Müller, A. Hinney, 2021, Scientific Reports.

Lipocalin 2 – mutation screen and serum levels in patients with anorexia nervosa or obesity and in lean individuals

S. Ehrlich, B. Herpertz-Dahlmann, J. Hebebrand, 2023, Frontiers in Endocrinology.

Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations.

D. Collier, M. Gratacós, X. Estivill, 2004, Human molecular genetics.

Associations between ADHD and various eating disorders : A Swedish nationwide population study using multiple genetically informative approaches

Hunna J. Watson, I. Ntalla, E. Zeggini, 2019 .

SDCCAG8 Obesity Alleles and Reduced Weight Loss After a Lifestyle Intervention in Overweight Children and Adolescents

M. Kleber, T. Illig, I. Heid, 2012, Obesity.

Binge-eating episodes are not characteristic of carriers of melanocortin-4 receptor gene mutations

J. Hebebrand, A. Hinney, H. Remschmidt, 2004, Molecular Psychiatry.

Evidence for an influence of TCF7L2 polymorphism rs7903146 on insulin resistance and sensitivity indices in overweight children and adolescents during a lifestyle intervention

J. Hebebrand, A. Hinney, T. Reinehr, 2008, International Journal of Obesity.

Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa

S. Ehrlich, B. Herpertz-Dahlmann, J. Hebebrand, 2023, Frontiers in Genetics.

Waist-hip ratio related genetic loci are associated with risk of impaired fasting glucose in Chinese children: a case control study

A. Hinney, Jun Ma, Jie-Yun Song, 2018, Nutrition & Metabolism.

Confidence Intervals for Genotype Relative Risks and Allele Frequencies from the Case Parent Trio Design for Candidate-Gene Studies

J. Hebebrand, A. Hinney, A. Scherag, 2003, Human Heredity.

Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder.

Susanne Walitza, Andreas Warnke, Michael Simons, 2006, The international journal of neuropsychopharmacology.

'Fat mass and obesity associated' gene (FTO): No significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents

J. Hebebrand, A. Hinney, A. Scherag, 2008, BMC Medical Genetics.

Fat Mass and Obesity-Associated Gene (FTO) in Eating Disorders: Evidence for Association of the rs9939609 Obesity Risk Allele with Bulimia nervosa and Anorexia nervosa

M. Gratacós, X. Estivill, H. Wichmann, 2012, Obesity Facts.

Human galanin (GAL) and galanin 1 receptor (GALR1) variations are not involved in fat intake and early onset obesity.

M. Platzer, W. Grassl, J. Hebebrand, 2005, The Journal of nutrition.

Nutrient-Gene Interactions Human Galanin ( GAL ) and Galanin 1 Receptor ( GALR 1 ) Variations Are Not Involved in Fat Intake and Early Onset Obesity 1 , 2

M. Platzer, W. Grassl, J. Hebebrand, 2005 .

Age at menarche relates to depression in adolescent girls: Comparing a clinical sample to the general pediatric population.

J. Hebebrand, A. Hinney, R. Kuhnert, 2022, Journal of affective disorders.

Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study

T. Illig, H. Grallert, J. Hebebrand, 2016, BMC Medical Genetics.

Causal attributions of obese men and women in genetic testing: Implications of genetic/biological attributions

W. Rief, J. Hebebrand, A. Hinney, 2009, Psychology & health.

A consultation with genetic information about obesity decreases self-blame about eating and leads to realistic weight loss goals in obese individuals.

W. Rief, J. Hebebrand, A. Hinney, 2009, Journal of psychosomatic research.

Procolipase Gene: No Association with Early-Onset Obesity or Fat Intake

T. Meitinger, M. Platzer, P. Lichtner, 2009, Obesity Facts.

A novel nonsense mutation in the melanocortin-4 receptor associated with obesity in a Spanish population

A. Martí, J. Hebebrand, A. Hinney, 2003, International Journal of Obesity.

No evidence for involvement of polymorphisms of the dopamine D4 receptor gene in anorexia nervosa, underweight, and obesity.

F. Poustka, J. Hebebrand, A. Hinney, 1999, American journal of medical genetics.

[Prevalence of melanocortin 4 receptor (MC4R) mutations and polymorphismsin consecutively ascertained obese children and adolescents from a pediatric health care utilization population].

J. Hebebrand, A. Hinney, L. Gortner, 2005, Klinische Padiatrie.

Brain-derived neurotrophic factor V66M polymorphism in childhood-onset obsessive-compulsive disorder.

K. Lesch, B. Herpertz-Dahlmann, A. Hinney, 2005, The international journal of neuropsychopharmacology.

Title : Association analyses for dopamine receptor gene polymorphisms and weight status : a cross-sectional case-control study and longitudinal analysis in obese children before and after lifestyle intervention Running title : Dopamine receptor polymorphisms and obesity

A. Hinney, T. Reinehr, C. Roth, 2013 .

TO JMG Large quantitative effect of melanocortin-4 receptor gene mutations on body mass index

T. Gudermann, A. Hinney, F. Geller, 2004 .

Serotonin transporter gene polymorphism (5-HTTLPR), environmental conditions, and developing negative emotionality and fear in early childhood

J. Hebebrand, A. Hinney, Susanne Friedl, 2009, Journal of Neural Transmission.

Combined family trio and case‐control analysis of the COMT Val158Met polymorphism in European patients with anorexia nervosa

M. Gratacós, X. Estivill, S. Sorbi, 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Evaluation of Metabolic Profiles of Patients with Anorexia Nervosa at Inpatient Admission, Short- and Long-Term Weight Regain—Descriptive and Pattern Analysis

J. Hebebrand, A. Hinney, J. Adamski, 2020, Metabolites.

Evaluation of the MC3R gene pertaining to body weight and height regulation and puberty development

J. Hebebrand, A. Hinney, A. Dempfle, 2023, Scientific reports.

No Relationship between Male Pubertal Timing and Depression: New Insights from Epidemiology and Mendelian Randomization

J. Hebebrand, A. Hinney, C. Grasemann, 2023, medRxiv.

No impact of obesity susceptibility loci on weight regain after a lifestyle intervention in overweight children

T. Illig, H. Grallert, J. Hebebrand, 2013, Journal of pediatric endocrinology & metabolism : JPEM.

[Genetic and epigenetic mechanisms in obesity].

A. Hinney, A. Volckmar, L. Schonnop, 2015, Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz.

Transmission disequilibrium studies in early onset of obsessive–compulsive disorder for polymorphisms in genes of the dopaminergic system

B. Herpertz-Dahlmann, K. Lange, A. Hinney, 2008, Journal of Neural Transmission.

No evidence for involvement of the promoter polymorphism -866 G/A of the UCP2 gene in childhood-onset obesity in humans.

J. Hebebrand, A. Hinney, H. Remschmidt, 2003, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

The 5-HT transporter genel inked polymorphic region ( 5H T T L P R ) in evolut ionary perspective : alternative biallelic variation in rhesus m o n k e y s Rapid Communication

S. Klauck, A. Poustka, F. Poustka, 2022 .

Case-control and combined family trios analysis of three polymorphisms in the ghrelin gene in European patients with anorexia and bulimia nervosa.

D. Collier, M. Gratacós, X. Estivill, 2006, Psychiatric genetics.

Screening for variability in the ciliary neurotrophic factor (CNTF) gene: No evidence for association with human obesity

H. Münzberg, J. Hebebrand, A. Hinney, 2009, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Further support for linkage of extreme obesity to the obese gene in a study group of obese children and adolescents.

K. Grzeschik, J. Hebebrand, A. Hinney, 2009, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Could leptin substitution therapy potentially terminate entrapment in anorexia nervosa?

J. Hebebrand, A. Hinney, J. Antel, 2023, Nature Reviews Endocrinology.

Common variants at 12q15 and 12q24 are associated with infant head circumference

Aad van der Lugt, Xavier Estivill, Sudha Seshadri, 2012, Nature Genetics.

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Alicia R. Martin, N. Eriksson, M. Daly, 2018, Nature Genetics.

A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

John J. Connolly, I. Ntalla, E. Zeggini, 2017, Scientific Reports.

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Thomas W. Mühleisen, David M. Evans, M. Jarvelin, 2013, Nature Genetics.

Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index

Henrik, Tanya M. Teslovich, Jennie, 2012 .

Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches

Hunna J. Watson, I. Ntalla, E. Zeggini, 2019, Biological Psychiatry.

Contents Vol. 77, 2012

F. Kronenberg, V. Tillmann, T. Stijnen, 2012, Hormone Research in Paediatrics.

Mapping the human genetic architecture of COVID-19

Mattia G. Bergomi, Christopher M. DeBoever, Matthew A. Wiles, 2021, Nature.

Allele frequencies of three 5-HT2A receptor gene polymorphisms in patients with anorexia nervosa, and in healthy underweight and obese individuals

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