D. Koshland

发表

A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae

V. Guacci, D. Koshland, A. Strunnikov, 1997, Cell.

Cse4p Is a Component of the Core Centromere of Saccharomyces cerevisiae

D. Koshland, P. Meluh, Peirong Yang, 1998, Cell.

Non-genetic individuality: chance in the single cell

D. Koshland, J. Spudich, D. Koshland, 1976, Nature.

Genome-Wide Mapping of the Cohesin Complex in the Yeast Saccharomyces cerevisiae

Earl F. Glynn, Joseph L DeRisi, J. Derisi, 2004, PLoS biology.

Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation

I R Gibbons, D. Koshland, I. Gibbons, 1995, The Journal of cell biology.

Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s)

V. Guacci, D. Koshland, A. Yamamoto, 1996, The Journal of cell biology.

Back to the Future: Mutant Hunts Are Still the Way To Go

Fred Winston, Douglas Koshland, F. Winston, 2016, Genetics.

Analysis of chromosome segregation in Saccharomyces cerevisiae.

F. Spencer, P. Hieter, D. Koshland, 1991, Methods in enzymology.

Mitotic chromosome condensation.

D. Koshland, A. Strunnikov, 1996, Annual review of cell and developmental biology.

SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family

D. Koshland, A. Strunnikov, V. Larionov, 1993, The Journal of cell biology.

Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p.

M. Kirschner, J. Peters, D. Koshland, 1996, Genes & development.

The anaphase inhibitor of Saccharomyces cerevisiae Pds1p is a target of the DNA damage checkpoint pathway.

D. Koshland, O. Cohen-Fix, D Koshland, 1997, Proceedings of the National Academy of Sciences of the United States of America.

SMC Complexes--Wrapped Up in Controversy

D. Koshland, M. Milutinovich, Mark Milutinovich, 2003, Science.

Evidence for posttranslational translocation of β-lactamase across the bacterial inner membrane

D. Botstein, D. Koshland, 1982, Cell.

Cohesin residency determines chromatin loop patterns

X. Darzacq, D. Koshland, Lorenzo Costantino, 2020, bioRxiv.

Cohesin residency determines chromatin loop patterns

X. Darzacq, D. Koshland, Lorenzo Costantino, 2020, eLife.

Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae

D. Koshland, T. Huffaker, R. Palmer, 1992, The Journal of cell biology.

Relation of protein subunit interactions to the molecular species observed during cooperative binding of ligands.

J. Haber, D. Koshland, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Polewards chromosome movement driven by microtubule depolymerization in vitro

M. Kirschner, T. Mitchison, D. Koshland, 1988, Nature.

Desiccation tolerance: an unusual window into stress biology

D. Koshland, Hugo Tapia, 2019, Molecular biology of the cell.

Differential roles of the RNases H in preventing chromosome instability

Anjali D. Zimmer, D. Koshland, 2016, Proceedings of the National Academy of Sciences.

Genetic Evidence that the Acetylation of the Smc3p Subunit of Cohesin Modulates Its ATP-Bound State to Promote Cohesion Establishment in Saccharomyces cerevisiae

D. Koshland, I. Onn, Jill M Heidinger-Pauli, 2010, Genetics.

Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast.

S. Emr, D. Koshland, A. Yamamoto, 1995, Molecular biology of the cell.

architecture and clustering in vivo.

D. Koshland, Siheng Xiang, 2021 .

Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae.

D. Koshland, E. Hogan, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae

D. Koshland, Michael Koval, R. Palmer, 1989, The Journal of cell biology.

Mitotic transmission of artificial chromosomes in cdc mutants of the yeast, Saccharomyces cerevisiae.

D. Koshland, R. Palmer, E. Hogan, 1990, Genetics.

Chromosome condensation and sister chromatid pairing in budding yeast

V. Guacci, D. Koshland, E. Hogan, 1994, The Journal of cell biology.

Centromere-dependent binding of yeast minichromosomes to microtubules in vitro

D. Koshland, J. Kingsbury, 1991, Cell.

Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae

V. Guacci, D. Koshland, A. Yamamoto, 1996, The Journal of cell biology.

Structure and function of chromosomes in mitosis of budding yeast.

V. Guacci, D. Koshland, A. Strunnikov, 1993, Cold Spring Harbor symposia on quantitative biology.

Centromere position in budding yeast: evidence for anaphase A.

V. Guacci, D. Koshland, V Guacci, 1997, Molecular biology of the cell.

Distinct targets of the Eco1 acetyltransferase modulate cohesion in S phase and in response to DNA damage.

D. Koshland, Elçin Unal, Jill M Heidinger-Pauli, 2009, Molecular cell.

Molecular biology. SMC complexes--wrapped up in controversy.

D. Koshland, Mark Milutinovich, 2003, Science.

Diverse effects of mutations in the signal sequence on the secretion of β-lactamase in Salmonella typhimurium

D. Botstein, R. Sauer, D. Koshland, 1982, Cell.

Genome-wide Map of R-Loop-Induced Damage Reveals How a Subset of R-Loops Contributes to Genomic Instability.

D. Koshland, Lorenzo Costantino, 2018, Molecular cell.

Centromere function on minichromosomes isolated from budding yeast.

D. Koshland, J. Kingsbury, 1993, Molecular biology of the cell.

A genetic analysis of dicentric minichromosomes in saccharomyces cerevisiae

L. Hartwell, D. Koshland, M. Fitzgerald‐Hayes, 1987, Cell.

Secretion of beta-lactamase requires the carboxy end of the protein

D. Botstein, D. Koshland, 1980, Cell.

Evidence for β-β interactions during the binding of oxygen to hemoglobin

J. Haber, D. Koshland, 1969 .

The Yin and Yang of R-loop biology.

D. Koshland, Lorenzo Costantino, 2015, Current opinion in cell biology.

RNase H enables efficient repair of R-loop induced DNA damage

D. Koshland, J. Amon, 2016, bioRxiv.

Trehalose Is a Versatile and Long-Lived Chaperone for Desiccation Tolerance

D. Koshland, Hugo Tapia, 2014, Current Biology.

Role of flexibility in the specificity, control and evolution of enzymes

D. Koshland, 1976, FEBS letters.

Competitive Repair by Naturally Dispersed Repetitive DNA during Non-Allelic Homologous Recombination

Maitreya J. Dunham, S. Celniker, R. Hoskins, 2010, PLoS genetics.

The Kinetochore Is an Enhancer of Pericentric Cohesin Binding

J. Derisi, D. Koshland, J. Gerton, 2004, PLoS biology.

The centromeric sister chromatid cohesion site directs Mcd1p binding to adjacent sequences.

V. Guacci, D. Koshland, P. Megee, 1999, Molecular cell.

Budding yeast centromere composition and assembly as revealed by in vivo cross-linking.

D. Koshland, P. Meluh, 1997, Genes & development.

A Conserved Domain in the Scc3 Subunit of Cohesin Mediates the Interaction with Both Mcd1 and the Cohesin Loader Complex

V. Guacci, D. Koshland, Thomas Eng, 2015, PLoS genetics.

Sister chromatid cohesion: a simple concept with a complex reality.

V. Guacci, D. Koshland, Elçin Unal, 2008, Annual review of cell and developmental biology.

In vivo dissection of the chromosome condensation machinery

D. Koshland, B. Lavoie, E. Hogan, 2002, The Journal of cell biology.

RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability.

D. Koshland, Lamia Wahba, Milena Vuica-Ross, 2011, Molecular cell.

Increasing intracellular trehalose is sufficient to confer desiccation tolerance to Saccharomyces cerevisiae

C. Bertozzi, D. Koshland, Douglas Fox, 2015, Proceedings of the National Academy of Sciences.

Segment-directed mutagenesis: construction in vitro of point mutations limited to a small predetermined region of a circular DNA molecule.

D. Botstein, G. Weinstock, D. Shortle, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery.

P. Hieter, D. Koshland, L. Corson, 1999, Genes & development.

SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family.

D. Koshland, A. Strunnikov, E. Hogan, 1995, Genes & development.

Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae

F. Spencer, P. Hieter, D. Koshland, 1996, Molecular and cellular biology.

Mitotic chromosome condensation requires Brn1p, the yeast homologue of Barren.

D. Koshland, C. Holm, S. Oh, 2000, Molecular biology of the cell.

Chromosomal Addresses of the Cohesin Component Mcd1p

V. Guacci, D. Koshland, S. Laloraya, 2000, The Journal of cell biology.

Ctf19p: A Novel Kinetochore Protein in Saccharomyces cerevisiae and a Potential Link between the Kinetochore and Mitotic Spindle

P. Hieter, D. Koshland, K. M. Hyland, 1999, The Journal of cell biology.

Pdslp Is Required for Faithful Execution of Anaphase in the Yeast

V. Guacci, D. Koshland, A. Yamamoto, 1996 .

Sister chromatid cohesion: the beginning of a long and beautiful relationship.

V. Guacci, D. Koshland, 2000, Current opinion in cell biology.

Pds1p of budding yeast has dual roles: inhibition of anaphase initiation and regulation of mitotic exit.

D. Koshland, O. Cohen-Fix, Doug Koshland, 1999, Genes & development.

Mitosis: Back to the basics

D. Koshland, 1994, Cell.

The metaphase-to-anaphase transition: avoiding a mid-life crisis.

D. Koshland, O. Cohen-Fix, 1997, Current opinion in cell biology.

Pds5p Is an Essential Chromosomal Protein Required for Both Sister Chromatid Cohesion and Condensation in Saccharomyces cerevisiae

V. Guacci, D. Koshland, K. Stead, 2000, The Journal of cell biology.

Cohesin architecture and clustering in vivo

D. Koshland, Siheng Xiang, 2021, eLife.

Cohesin in space and time: architecture and oligomerization in vivo

D. Koshland, Siheng Xiang, 2020, bioRxiv.

Communication between distinct subunit interfaces of the cohesin complex promotes its topological entrapment of DNA

V. Guacci, D. Koshland, Brett Robison, 2019, bioRxiv.

Cohesin Function in Cohesion, Condensation, and DNA Repair Is Regulated by Wpl1p via a Common Mechanism in Saccharomyces cerevisiae

V. Guacci, D. Koshland, Michelle S. Bloom, 2017, Genetics.

A role for the Smc3 hinge domain in the maintenance of sister chromatid cohesion

V. Guacci, D. Koshland, Brett Robison, 2017, bioRxiv.

Interallelic complementation provides functional evidence for cohesin–cohesin interactions on DNA

V. Guacci, D. Koshland, Thomas Eng, 2015, Molecular biology of the cell.

A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase

V. Guacci, D. Koshland, Michelle S. Bloom, 2015, Molecular biology of the cell.

ROCC, a conserved region in cohesin's Mcd1 subunit, is essential for the proper regulation of the maintenance of cohesion and establishment of condensation

V. Guacci, D. Koshland, Thomas Eng, 2014, Molecular biology of the cell.

Cohesin-independent segregation of sister chromatids in budding yeast

V. Guacci, D. Koshland, 2012, Molecular biology of the cell.

Systematic Reduction of Cohesin Differentially Affects Chromosome Segregation, Condensation, and DNA Repair

V. Guacci, D. Koshland, Jill M Heidinger-Pauli, 2010, Current Biology.

The zinc finger of Eco1 enhances its acetyltransferase activity during sister chromatid cohesion

V. Guacci, D. Koshland, I. Onn, 2009, Nucleic acids research.

The zinc finger of Eco 1 enhances its acetyltransferase activity during sister chromatid cohesion

V. Guacci, D. Koshland, I. Onn, 2009 .

A Molecular Determinant for the Establishment of Sister Chromatid Cohesion

Steven P. Gygi, Woong Kim, S. Gygi, 2008, Science.

The kleisin subunit of cohesin dictates damage-induced cohesion.

V. Guacci, D. Koshland, Elçin Unal, 2008, Molecular cell.

DNA Double-Strand Breaks Trigger Genome-Wide Sister-Chromatid Cohesion Through Eco1 (Ctf7)

D. Koshland, E. Ünal, Jill M Heidinger-Pauli, 2007, Science.

A Multi-Step Pathway for the Establishment of Sister Chromatid Cohesion

D. Koshland, R. Skibbens, E. Ünal, 2006, PLoS genetics.

The structure of sister minichromosome DNA before anaphase in Saccharomyces cerevisiae.

L. Hartwell, D. Koshland, 1987, Science.

Visual assay for chromosome ploidy.

P. Hieter, D. Koshland, 1987, Methods in enzymology.

S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation

Anjali D. Zimmer, D. Koshland, Lorenzo Costantino, 2016, Genes & development.

DNA Resection at Chromosome Breaks Promotes Genome Stability by Constraining Non-Allelic Homologous Recombination

D. Koshland, F. Tan, M. Hoang, 2012, PLoS genetics.

In vivo requirements for rDNA chromosome condensation reveal two cell-cycle-regulated pathways for mitotic chromosome folding.

D. Koshland, B. Lavoie, E. Hogan, 2004, Genes & development.

Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin.

D. Koshland, E. Greene, Johannes Stigler, 2016, Cell reports.

Rings, bracelet or snaps: fashionable alternatives for Smc complexes

D. Koshland, Catherine E. Huang, Mark Milutinovich, 2005, Philosophical Transactions of the Royal Society B: Biological Sciences.

The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability

D. Koshland, Steven K Gore, Lamia Wahba, 2013, eLife.

Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation.

D. Koshland, G. Pielak, L. Rebecchi, 2017, Molecular cell.

Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C.

D. Koshland, P. Meluh, 1995, Molecular biology of the cell.

CEP3 encodes a centromere protein of Saccharomyces cerevisiae

D. Koshland, A. Strunnikov, J. Kingsbury, 1995, The Journal of cell biology.

Genetic analysis of the mitotic transmission of minichromosomes

L. Hartwell, D. Koshland, J. Kent, 1985, Cell.

DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain.

Michael Lichten, Ulrike Sattler, James E Haber, 2004, Molecular cell.

The Rs of biology: R-loops and the regulation of regulators.

D. Koshland, Lamia Wahba, 2013, Molecular cell.

A functional assay for centromere-associated sister chromatid cohesion.

D. Koshland, P. Megee, Douglas Koshland, 1999, Science.

TOR and RAS pathways regulate desiccation tolerance in Saccharomyces cerevisiae

D. Botstein, D. Koshland, P. Gibney, 2013, Molecular biology of the cell.

Chromosome integrity in Saccharomyces cerevisiae: the interplay of DNA replication initiation factors, elongation factors, and origins.

D. Koshland, Dongli Huang, 2003, Genes & development.

Chromosome Morphogenesis: Condensin-Dependent Cohesin Removal during Meiosis

D. Koshland, Hong-Guo Yu, 2005, Cell.

Meiotic condensin is required for proper chromosome compaction, SC assembly, and resolution of recombination-dependent chromosome linkages

D. Koshland, Hong-Guo Yu, 2003, The Journal of cell biology.

The CDC20 gene product of Saccharomyces cerevisiae, a beta-transducin homolog, is required for a subset of microtubule-dependent cellular processes

D. Koshland, D. Burke, D J Burke, 1991, Molecular and cellular biology.

Intermediate step of cohesin’s ATPase cycle allows cohesin to entrap DNA

D. Koshland, Kristian K. Carlborg, Gamze Ö. Çamdere, 2018, Proceedings of the National Academy of Sciences.

Budding yeast Wpl1p regulates cohesin functions in cohesion, condensation and DNA repair by a common mechanism

V. Guacci, D. Koshland, Michelle S. Bloom, 2017, bioRxiv.

A role for the Smc 3 hinge domain in the maintenance of sister chromatid 1 cohesion 2 3

V. Guacci, D. Koshland, Brett Robison, 2017 .

The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering

V. Guacci, D. Koshland, Gamze Ö. Çamdere, 2015, eLife.

In vitro assembly of physiological cohesin/DNA complexes

D. Koshland, I. Onn, 2011, Proceedings of the National Academy of Sciences.

The Aurora kinase Ipl1 maintains the centromeric localization of PP2A to protect cohesin during meiosis

D. Koshland, Hong-Guo Yu, 2007, The Journal of cell biology.

Unifying forces for chromosomes in mitosis

D. Koshland, 1992, Current Biology.

Genetic Analysis of Desiccation Tolerance in Saccharomyces cerevisiae

D. Koshland, M. Dunham, Christopher G. DeSevo, 2011, Genetics.

An evaluation of the relatedness of proteins based on comparison of amino acid sequences.

J. Haber, D. Koshland, D. E. Koshland, 1970, Journal of molecular biology.

Synergy between the small intrinsically disordered protein Hsp12 and trehalose sustain viability after severe desiccation

D. Koshland, Xuchen Hu, Hugo Tapia, 2018, eLife.

A simple colony‐formation assay in liquid medium, termed ‘tadpoling’, provides a sensitive measure of Saccharomyces cerevisiae culture viability

D. Koshland, Aaron Z. Welch, 2013, Yeast.

Author response: The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability

D. Koshland, Steven K Gore, Lamia Wahba, 2013 .

Synergism between a simple sugar and a small intrinsically disordered protein mitigate the lethal stresses of severe water loss

D. Koshland, Xuchen Hu, Hugo Tapia, 2017, bioRxiv.

The spatial regulation of condensin activity in chromosome condensation

D. Koshland, Lorenzo Costantino, R. Lamothe, 2019, bioRxiv.