Weining Lu

发表

Characterization of apparently balanced chromosomal rearrangements from the developmental genome anatomy project.

J. Shendure, M. MacDonald, S. Kulkarni, 2008, American journal of human genetics.

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Jing Zhou, Donald E. Ingber, Surya M. Nauli, 2003, Nature Genetics.

Integrin-Linked Kinase Deficiency in Collecting Duct Principal Cell Promotes Necroptosis of Principal Cell and Contributes to Kidney Inflammation and Fibrosis.

M. Huang, Weining Lu, Baoxue Yang, 2019, Journal of the American Society of Nephrology : JASN.

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

Kristen M. Laricchia, Thomas M. Kitzler, D. MacArthur, 2020, American journal of human genetics.

Blocking peptides and molecular mimicry as treatment for kidney disease.

Weining Lu, Zhiyong Wang, S. Borkan, 2017, American journal of physiology. Renal physiology.

Direct negative crosstalk between SLIT2 and BMP-Gremlin signaling 1 Identification of direct negative crosstalk between the SLIT2 and Bone Morphogenetic Protein– Gremlin signaling pathways

Weining Lu, P. Bajaj, S. Berasi, 2018 .

Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein–Gremlin signaling pathways

Weining Lu, P. Bajaj, S. Berasi, 2018, The Journal of Biological Chemistry.

Roundabout receptor 2 maintains inhibitory control of the adult midbrain

R. Wong, M. Hoon, Weining Lu, 2017, eLife.

Mutations of the SLIT 2-ROBO 2 pathway genes SLIT 2 and SRGAP 1 Confer Risk for Congenital Anomalies of the Kidney and Urinary Tract

Soliman, Weining Lu, V. Tasic, 2015 .

Regulation of Ureteric Bud Outgrowth and the Consequences of Disrupted Development

Weining Lu, S. Nigam, K. Bush, 2016 .

Lower urinary tract development and disease

Weining Lu, H. Rasouly, 2013, Wiley interdisciplinary reviews. Systems biology and medicine.

OF LOWER URINARY TRACT DEVELOPMENT Development of the Ureter and Ureteral Peristaltic Machinery

Weining Lu, H. Rasouly, 2013 .

PODO: Trial Design: Phase 2 Study of PF-06730512 in Focal Segmental Glomerulosclerosis

Donal N. Gorman, Weining Lu, D. Salant, 2021, Kidney international reports.

Noninvasive Assessment of Antenatal Hydronephrosis in Mice Reveals a Critical Role for Robo2 in Maintaining Anti-Reflux Mechanism

Weining Lu, D. Salant, C. Mendelsohn, 2011, PloS one.

Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux.

J. Lupski, C. Wijmenga, S. Kulkarni, 2007, American journal of human genetics.

Loss of Roundabout Guidance Receptor 2 (Robo2) in Podocytes Protects Adult Mice from Glomerular Injury by Maintaining Podocyte Foot Process Structure.

K. Coser, Weining Lu, D. Salant, 2020, The American journal of pathology.

Tissue-specific reduction in splicing efficiency of IKBKAP due to the major mutation associated with familial dysautonomia.

J. Gusella, Weining Lu, D. Zagzag, 2003, American journal of human genetics.

The fate of Notch-deficient nephrogenic progenitor cells during metanephric kidney development.

Weining Lu, D. Salant, L. Beck, 2011, Kidney international.

Copy Number Variation Analysis Facilitates Identification of Genetic Causation in Patients with Congenital Anomalies of the Kidney and Urinary Tract

Richard S. Lee, S. Mane, S. Bauer, 2022, European urology open science.

Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development.

Richard S. Lee, Amita Sharma, E. Mancini, 2015, American journal of human genetics.

Cloning and functional analysis of the mouse 5-lipoxygenase promoter.

Weining Lu, J. Hjoberg, E. Silverman, 2002, American journal of respiratory cell and molecular biology.

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

Weining Lu, Jing Zhou, G. Brent, 1997, Nature Genetics.

ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis

Weining Lu, D. Salant, Xueping Fan, 2022, JCI insight.

Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis

M. Justice, R. Bronson, Weining Lu, 2002, Nature Genetics.

Disruption of diacylglycerol kinase delta (DGKD) associated with seizures in humans and mice.

M. Kelz, K. Ligon, J. Gusella, 2007, American journal of human genetics.

SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.

Mostafa E. Belghasem, Weining Lu, D. Salant, 2016, JCI insight.

NFIA Haploinsufficiency Is Associated with a CNS Malformation Syndrome and Urinary Tract Defects

C. Walsh, K. Devriendt, J. Gusella, 2007, PLoS genetics.

A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish

K. Dewar, Weining Lu, D. Beier, 2002, Development.

Disruption of ROBO2 Is Associated with Urinary Tract Anomalies and Confers Risk of Vesicoureteral Reflux

J. Lupski, C. Wijmenga, S. Kulkarni, 2007 .

Mutations of the SLIT2–ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract

Weining Lu, R. Lifton, V. Tasic, 2015, Human Genetics.

MATR3 disruption in human and mouse associated with bicuspid aortic valve, aortic coarctation and patent ductus arteriosus

Ronald Berezney, Kasper Lage, Raymond M. Anchan, 2015, Human molecular genetics.

MATR 3 disruption in human and mouse associated with bicuspid aortic valve , aortic coarctation and patent ductus arteriosus

K. Lage, J. Gusella, C. Morton, 2015 .

Models for microarray gene expression data

G A Whitmore, G. A. Whitmore, Mei-Ling Ting Lee, 2002, Journal of biopharmaceutical statistics.

Piezo mechanosensory channels regulate centrosome integrity

J. Shah, Weining Lu, R. Maas, 2022, bioRxiv.

Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract.

Kristen M. Laricchia, Thomas M. Kitzler, Richard S. Lee, 2018, Journal of the American Society of Nephrology : JASN.

Mutations of the SLIT2–ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract

Weining Lu, R. Lifton, V. Tasic, 2015, Human Genetics.

A homozygous missense variant in VWA2, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux

S. Mane, S. Bauer, Weining Lu, 2018, PloS one.

Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure.

M. Mclaughlin, Weining Lu, R. Kalluri, 2012, Cell reports.

A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling.

S. Bauer, Weining Lu, D. Magen, 2017, Journal of the American Society of Nephrology : JASN.

Late onset of renal and hepatic cysts in Pkd1-targeted heterozygotes

N. Rifai, Weining Lu, P. Harris, 1999, Nature Genetics.

Inhibition of HER-2(neu/ErbB2) restores normal function and structure to polycystic kidney disease (PKD) epithelia.

Weining Lu, P. Wilson, Jing Zhou, 2006, Biochimica et biophysica acta.

Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.

Weining Lu, R. Maas, D. Salant, 2016, Kidney international.

Mutations in NRIP 1 cause dominant urinary tract malformations via dysregulation of retinoic acid signaling

Yair, Weining Lu, D. Magen, 2017 .

Crim1 regulates integrin signaling in murine lens development

Joshua W. K. Ho, Wilhelmine N. de Vries, Richard A. Lang, 2016, Journal of Cell Science.

Crim1 regulates integrin signaling in murine lens development

Weining Lu, R. Maas, S. Lachke, 2016, Development.

Distribution and developmentally regulated expression of murine polycystin.

Weining Lu, Jing Zhou, A. Pavlova, 1997, The American journal of physiology.

ETV4 Mutation in a Patient with Congenital Anomalies of the Kidney and Urinary Tract

S. Bauer, R. Wenger, Weining Lu, 2016, International Journal of Pediatrics and Child Health.

SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.

Mostafa E. Belghasem, Weining Lu, D. Salant, 2016, JCI insight.