F. Mseeh

发表

Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655

J. W. Campbell, J. W. Campbell, A. Barabasi, 2003, Journal of bacteriology.

NOTUM inhibition increases endocortical bone formation and bone strength

F. Mseeh, S. Movérare-Skrtic, C. Ohlsson, 2019, Bone Research.

LX4211 Increases Serum GLP-1 and PYY Levels by Reducing SGLT-1-mediated Absorption of Intestinal Glucose

F. Mseeh, D. Powell, A. Sands, 2013 .

Inactivation of platelet PDE2 by an affinity label: 8-[(4-bromo-2, 3-dioxobutyl)thio]cAMP.

R. Colman, F. Mseeh, R. Colman, 2000, Thrombosis research.

Improved glycemic control in mice lacking Sglt1 and Sglt2.

F. Mseeh, Z. Ding, D. Powell, 2013, American journal of physiology. Endocrinology and metabolism.

LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Effect of LX4211 on Glucose Homeostasis and Body Composition in Preclinical Models

F. Mseeh, P. Yalamanchili, A. Nouraldeen, 2014 .

Effect of LX 4211 on Glucose Homeostasis and Body Composition in Preclinical Models s

Alan G. E. Wilson, F. Mseeh, Z. Ding, 2014 .

Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme.

P. Mandal, Jason P. Burke, F. Mseeh, 2021, Journal of medicinal chemistry.

LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2015, Pharmacology research & perspectives.

Discovery of 6-[(3S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor.

P. Mandal, Jason P. Burke, F. Mseeh, 2021, Journal of medicinal chemistry.

Inhibition of dual leucine zipper kinase prevents chemotherapy-induced peripheral neuropathy and cognitive impairments

S. Kesler, Bo Peng, F. Mseeh, 2021, Pain.

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.

R. DePinho, M. Warmoes, F. Mseeh, 2019, Cell reports.

Lrp5 functions in bone to regulate bone mass

F. Mseeh, A. Robling, M. Warman, 2011, Nature Medicine.

Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

Justin K. Huang, P. Mandal, Jason P. Burke, 2020, Cancer Research.

Novel L-xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2009, Journal of medicinal chemistry.

Crystal structure of human riboflavin kinase reveals a beta barrel fold and a novel active site arch.

N. Grishin, A. Osterman, F. Mseeh, 2003, Structure.

From Genetic Footprinting to Antimicrobial Drug Targets: Examples in Cofactor Biosynthetic Pathways

Mark D'Souza, J. W. Campbell, Axel Bernal, 2002, Journal of bacteriology.

Discovery of IACS-9439, a potent, exquisitely selective and orally bioavailable inhibitor of CSF1R.

P. Mandal, Jason P. Burke, F. Mseeh, 2020, Journal of medicinal chemistry.

Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655

J. W. Campbell, J. W. Campbell, A. Barabasi, 2003, Journal of Bacteriology.

Identification of potent and selective MTH1 inhibitors.

F. Mseeh, C. Toniatti, G. Draetta, 2005, Bioorganic & medicinal chemistry letters.

LX4211 Increases Serum Glucagon-Like Peptide 1 and Peptide YY Levels by Reducing Sodium/Glucose Cotransporter 1 (SGLT1)–Mediated Absorption of Intestinal Glucose

F. Mseeh, Z. Ding, D. Powell, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Identification of cysteines involved in ligand binding to the human melatonin MT(2) receptor.

F. Mseeh, Matthew J Gerdin, Faika Mseeh, 2002, European journal of pharmacology.

Identification of Small Molecules That Selectively Inhibit Diacylglycerol Lipase–α Activity

Nghi Nguyen, Barbara J. Robertson, David G. Harden, 2014, Journal of biomolecular screening.

LX4211, a Dual SGLT1/SGLT2 Inhibitor, Improved Glycemic Control in Patients With Type 2 Diabetes in a Randomized, Placebo-Controlled Trial

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2012, Clinical pharmacology and therapeutics.

Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes.

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2017, Journal of medicinal chemistry.

Mutagenesis studies of the human MT2 melatonin receptor.

M. Dubocovich, F. Mseeh, Margarita L Dubocovich, 2003, Biochemical pharmacology.

Effect of LX4211 on Glucose Homeostasis and Body Composition in Preclinical Models

Alan G. E. Wilson, F. Mseeh, Z. Ding, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Abstract 3277: IACS-9779, a development candidate that inhibits 2,3-dioxygenase (IDO) activity by blocking heme incorporation into IDO apoenzyme

F. Mseeh, T. Heffernan, Ningping Feng, 2019, Clinical Research (Excluding Clinical Trials).

Improved glycemic control in mice lacking Sglt1 and Sglt2.

F. Mseeh, Z. Ding, D. Powell, 2013, American journal of physiology. Endocrinology and metabolism.

LX4211 Increases Serum Glucagon-Like Peptide 1 and Peptide YY Levels by Reducing Sodium/Glucose Cotransporter 1 (SGLT1)–Mediated Absorption of Intestinal Glucose

F. Mseeh, Z. Ding, D. Powell, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Identification of potent and selective MTH1 inhibitors.

F. Mseeh, C. Toniatti, G. Draetta, 2005, Bioorganic & Medicinal Chemistry Letters.