Aseem Kumar

发表

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*

K. Wood, Anand Kumar, D. Roberts, 2006, Critical care medicine.

Cytokine modulation in sepsis and septic shock

Anand Kumar, Anand Kumar, S. Zanotti, 2002, Expert opinion on investigational drugs.

Cationic glyconanoparticles: their complexation with DNA, cellular uptake, and transfection efficiencies.

Aseem Kumar, R. Narain, Shiyong Liu, 2009, Bioconjugate chemistry.

Bacterial RNA induces myocyte cellular dysfunction through the activation of PKR.

Anand Kumar, J. Parrillo, Aseem Kumar, 2012, Journal of thoracic disease.

2-5A-Antisense: A Novel Approach to Cancer Therapy

B. Williams, R. Silverman, Aseem Kumar, 1995 .

Pathway mapping of leukocyte transcriptome in influenza patients reveals distinct pathogenic mechanisms associated with progression to severe infection

K. Schughart, M. Nalos, Anand Kumar, 2020, BMC Medical Genomics.

Transcriptional Regulation of Fas Gene Expression by GA-binding Protein and AP-1 in T Cell Antigen Receptor·CD3 Complex-stimulated T Cells*

J. Parrillo, Aseem Kumar, R. Kimberly, 1999, The Journal of Biological Chemistry.

The effect of daily bathing with chlorhexidine on the acquisition of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and healthcare-associated bloodstream infections: Results of a quasi-experimental multicenter trial

Aseem Kumar, S. Kethireddy, 2010 .

Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection

Stephen J. Huang, K. Schughart, R. Geffers, 2019, Nature Communications.

Cloning and Characterization of the Human Heparanase-1 (HPR1) Gene Promoter

J. Parrillo, Aseem Kumar, J. Platt, 2002, The Journal of Biological Chemistry.

Protective effects of methyl gallate on H2O2-induced apoptosis in PC12 cells.

Aseem Kumar, J. Eibl, I. Tai, 2010, Biochemical and biophysical research communications.

Novel therapies for sepsis: antiendotoxin therapies

D. Feinstein, Aseem Kumar, Amit Kumar, 2002, Expert opinion on investigational drugs.

Transforming growth factor-&bgr;1 blocks in vitro cardiac myocyte depression induced by tumor necrosis factor-&agr;, interleukin-1&bgr;, and human septic shock serum

Anand Kumar, J. Parrillo, Aseem Kumar, 2007 .

BACTERIAL DNA AND RNA INDUCE RAT CARDIAC MYOCYTE CONTRACTION DEPRESSION IN VITRO

Anand Kumar, J. Parrillo, Aseem Kumar, 2004, Shock.

Nitric oxide and inflammatory cytokines in the heart: the presence of positive feedback loops.

Anand Kumar, Aseem Kumar, 2005, Critical care medicine.

Interleukin-1 gene cluster polymorphisms: all in the family.

Anand Kumar, J. Parrillo, Aseem Kumar, 2002, Critical care medicine.

Not only a toll for viruses: the role of toll-like receptor 3 in nonviral sepsis-induced cardiac depression.

Anand Kumar, Aseem Kumar, Farag A Bleiblo, 2012, Critical care medicine.

Relationship of Blood Transfusion and Clinical Outcomes in Patients With Acute Coronary SyndromesRao SV, Jollis JG, Harrington RA, et al (Duke Univ, Durham, NC; Univ of Alberta, Edmonton, Canada; Univ of Kentucky, Lexington; et al) JAMA 292:1555–1562, 2004§

C. Bekes, Aseem Kumar, S. Topalian, 2006 .

Dexamethasone and length of hospital stay in patients with community-acquired pneumonia: a randomised, double-blind, placebo-controlled trial

Aseem Kumar, S. Kethireddy, M. Blouw, 2012 .

Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection

Aseem Kumar, S. Kethireddy, 2012 .

Timing of Oseltamivir Administration and Outcomes in Hospitalized Adults With Pandemic 2009 Influenza A(H1N1) Virus Infection

Aseem Kumar, S. Kethireddy, 2012 .

Role of alveolar epithelial early growth response-1 (Egr-1) in CD8+ T cell-mediated lung injury.

Aseem Kumar, C. Ramana, H. Kwon, 2009, Molecular immunology.

STAT1 and STAT2 Null Cells Are Resistant to RNA-Induced Apoptosis Due to Deficiency in Constitutive and Inducible Apoptosis-Regulating Genes

Anand Kumar, J. Parrillo, Aseem Kumar, 2020, American Journal of Molecular Biology.

Methicillin-Resistant Staphylococcus aureus Central Line–Associated Bloodstream Infections in US Intensive Care Units, 1997-2007

Aseem Kumar, S. Kethireddy, 2010 .

Cardiac phenylethanolamine N-methyltransferase: localization and regulation of gene expression in the spontaneously hypertensive rat.

Aseem Kumar, N. Khaper, T. Tai, 2016, Canadian journal of physiology and pharmacology.

Draft 1 Cardiac Phenylethanolamine N-methyltransferase : Localization and Regulation of Gene Expression in the Spontaneously Hypertensive Rat

Aseem Kumar, N. Khaper, T. Tai, 2015 .

Abstract # 105: A Parturient with TTP Complicated with Severe Pre-Eclampsia

Aseem Kumar, M. D. Li, 2011 .

Inflammatory impact of IFN-γ in CD8+ T cell-mediated lung injury is mediated by both Stat1-dependent and -independent pathways.

Aseem Kumar, C. Ramana, J. Durbin, 2015, American journal of physiology. Lung cellular and molecular physiology.

CALL PAPERS Translational Research in Acute Lung Injury and Pulmonary Fibrosis Inﬂammatory impact of IFN- (cid:2) in CD8 (cid:3) T cell-mediated lung injury is mediated by both Stat1-dependent and -independent pathways

Aseem Kumar, C. Ramana, J. Durbin, 2015 .

Community-Acquired Respiratory Coinfection in Critically III Patients With Pandemic 2009 Influenza A(H1N1) Virus

Aseem Kumar, S. Kethireddy, M. Blouw, 2012 .

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF‐1 and NF‐κB

B. Williams, Aseem Kumar, L. Reis, 1997, The EMBO journal.

Design and Evaluation of Gastro-retentive Drug Delivery System for Glimepiride using Design of Experiment

Aseem Kumar, R. Dutt, Anil K. Sharma, 2022, International Journal of Pharmaceutical Sciences and Drug Research.

Liposomal bismuth-ethanedithiol formulation enhances antimicrobial activity of tobramycin.

Aseem Kumar, Abdelwahab Omri, Z. Suntres, 2008, International journal of pharmaceutics.

CHAPTER 57 ■ SEPSIS AND SEPTIC SHOCK

Anand Kumar, Aseem Kumar, Anand Kumar, 2008 .

Myocardial Dysfunction in Sepsis and Septic Shock

Anand Kumar, J. Parrillo, Aseem Kumar, 2008 .

Myocardial dysfunction in the patient with sepsis

Anand Kumar, J. Parrillo, Aseem Kumar, 2002, Current opinion in critical care.

Clinical review: Myocardial depression in sepsis and septic shock

Anand Kumar, J. Parrillo, Aseem Kumar, 2002, Critical care.

Inflammatory Signaling in Hypertension: Regulation of Adrenal Catecholamine Biosynthesis

Aseem Kumar, T. Tai, S. Khurana, 2018, Front. Endocrinol..

Epidemiology, management, and risk factors for death of invasive Candida infections in critical care: A multicenter, prospective, observational study in France (2005–2006)

Aseem Kumar, S. Kethireddy, Aseem Kumar, 2010 .

Impact of Vancomycin Exposure on Outcomes in Patients With Methicillin-Resistant Staphylococcus aureus Bacteremia: Support for Consensus Guidelines Suggested Targets

Aseem Kumar, S. Kethireddy, 2012 .

β-d-Glucan Assay for the Diagnosis of Invasive Fungal Infections: A Meta-analysis

Aseem Kumar, S. Kethireddy, 2012 .

Bactericidal efficacy of liposomal aminoglycosides against Burkholderia cenocepacia.

Aseem Kumar, Abdelwahab Omri, R. Lafrenie, 2007, The Journal of antimicrobial chemotherapy.

Stat1-independent induction of SOCS-3 by interferon-gamma is mediated by sustained activation of Stat3 in mouse embryonic fibroblasts.

Aseem Kumar, C. Ramana, R. Enelow, 2005, Biochemical and biophysical research communications.

Characterization of human septic sera induced gene expression modulation in human myocytes.

J. Parrillo, Aseem Kumar, K. Passi, 2009, International journal of clinical and experimental medicine.

Identification and characterization of interferon and double-stranded RNA signal transduction pathways

Aseem Kumar, 1997 .

Reversible myocardial dysfunction: an ubiquitous phenomenon in the critically ill?

Anand Kumar, J. Parrillo, Aseem Kumar, 2002, Critical care medicine.

Elevated lipid peroxidants in breast cancer patients

Aseem Kumar, R. Sinha, 2014 .

The role of immunostimulatory nucleic acids in septic shock.

J. Parrillo, Aseem Kumar, C. Ramana, 2012, International journal of clinical and experimental medicine.

Reverse-phase High-Performance Liquid Chromatography Method Development and Validation for Estimation of Glimepiride in Bulk and Tablet Dosage Form

Aseem Kumar, A. Sharma, R. Dutt, 2020 .

Regulation of gene expression in RAW 264.7 macrophage cell line by interferon-γ

Aseem Kumar, K. Gohil, C. Ramana, 2006 .

Defective TNF-α-Induced Apoptosis in STAT1-Null Cells Due to Low Constitutive Levels of Caspases

Aseem Kumar, C. Horvath, G. Stark, 1997 .

Culture-Negative Septic Shock Compared With Culture-Positive Septic Shock: A Retrospective Cohort Study

J. Parrillo, Aseem Kumar, H. Kirchner, 2018, Critical care medicine.

Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock.

Anand Kumar, D. Roberts, B. Light, 2009, Chest.

Influenza A induced cellular signal transduction pathways.

Aseem Kumar, C. Ramana, S. Khurana, 2013, Journal of thoracic disease.

A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection

Stephen J. Huang, K. Schughart, R. Geffers, 2017, European Respiratory Journal.

Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study

Daniel Feinstein, Kenneth E Wood, K. Wood, 2013, Critical Care.

Mycobacterium tuberculosis septic shock.

S. Lapinsky, Anand Kumar, J. Parrillo, 2013, Chest.

Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: A propensity-matched analysis*

S. Lapinsky, Anand Kumar, B. Light, 2010, Critical care medicine.

Fulminant Clostridium difficile Colitis: Patterns of Care and Predictors of Mortality

Aseem Kumar, S. Kethireddy, 2010 .

Survival in Human Septic Shock Therapy Results in a Fivefold Reduction of Initiation of Inappropriate Antimicrobial

D. Roberts, B. Light, J. Parrillo, 2009 .

Human Serum from Patients with Septic Shock Activates Transcription Factors STAT1, IRF1, and NF-κB and Induces Apoptosis in Human Cardiac Myocytes*

J. Parrillo, Aseem Kumar, C. Ramana, 2005, Journal of Biological Chemistry.

Nitric oxide-dependent and -independent mechanisms are involved in TNF-alpha -induced depression of cardiac myocyte contractility.

Anand Kumar, J. Parrillo, Aseem Kumar, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Association between source of infection and hospital mortality in patients who have septic shock.

Anand Kumar, Aseem Kumar, P. Dodek, 2014, American journal of respiratory and critical care medicine.

The impact of obesity in cirrhotic patients with septic shock: A retrospective cohort study

S. Keenan, Anand Kumar, Aseem Kumar, 2018, Liver international : official journal of the International Association for the Study of the Liver.

Septic sera induces apoptosis and DNA fragmentation factor 40 activation in fibroblasts.

J. Parrillo, Aseem Kumar, C. Ramana, 2011, Biochemical and biophysical research communications.

Procalcitonin and C-Reactive Protein in Hospitalized Adult Patients With Community-Acquired Pneumonia or Exacerbation of Asthma or COPD

Aseem Kumar, S. Kethireddy, M. Blouw, 2012 .

JAK kinases are required for the bacterial RNA and poly I:C induced tyrosine phosphorylation of PKR.

J. Parrillo, Aseem Kumar, C. Ramana, 2013, International journal of clinical and experimental medicine.

The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels.

S. Opal, J. Parrillo, Leo Taiberg, 2006, The Journal of infectious diseases.

TRANFORMING GROWTH FACTOR (TGF)-beta INHIBITS HUMAN SEPTIC SERUM-INDUCED DEPRESSION OF CARDIAC MYOCYTE CONTRACTILITY

J. Parrillo, Aseem Kumar, Amit Kumar, 1999 .

Non-pulmonary infections but not specific pathogens are associated with increased risk of AKI in septic shock

S. Keenan, N. Tangri, Anand Kumar, 2014, Intensive Care Medicine.

Predicting in-hospital mortality in pneumonia-associated septic shock patients using a classification and regression tree: a nested cohort study

Aseem Kumar, Y. Mirzanejad, J. Speiser, 2018, Journal of Intensive Care.

Activated protein C and septic shock: A propensity-matched cohort study*

K. Wood, J. Marshall, Anand Kumar, 2012, Critical care medicine.

Involvement of Rho kinase (ROCK) in sepsis-induced acute lung injury.

J. Parrillo, Aseem Kumar, L. Tamer, 2012, Journal of thoracic disease.

Endotoxemic myocardial depression: a novel inducible nitric oxide synthase suppressant effect of albumin.

Anand Kumar, Aseem Kumar, Anand Kumar, 2003, Critical care medicine.

O R I G I N A L A R T I C L E Involvement of Rho kinase (ROCK) in sepsis-induced acute lung injury

Anand Kumar, J. Parrillo, Aseem Kumar, 2011 .

Oxidative Stress Mediates the Fetal Programming of Hypertension by Glucocorticoids

Aseem Kumar, N. Khaper, S. Lees, 2021, Antioxidants.

COMBINED ASSESSMENT OF LIPID PEROXIDATION, CEA AND CA19.9 BIO - MARKERS IN ADVANCED STAGE GALL BLADDER CANCER

Aseem Kumar, Manisha Singh, P. Das, 2015 .

Pathway mapping of leukocyte transcriptome in influenza patients reveals distinct pathogenic mechanisms associated with progression to severe infection

K. Schughart, M. Nalos, Aseem Kumar, 2020, BMC Medical Genomics.

Severity of Meningococcal Disease Associated with Genomic Bacterial Load

Aseem Kumar, S. Kethireddy, 2010 .

Procalcitonin-guided interventions against infections to increase early appropriate antibiotics and improve survival in the intensive care unit: A randomized trial

Aseem Kumar, S. Kethireddy, M. Blouw, 2012 .

Fungicidal versus fungistatic therapy of invasive Candida infection in non-neutropenic adults: a meta-analysis

Anand Kumar, Aseem Kumar, R. Zarychanski, 2018, Mycology.

Translational Research in Acute Lung Injury and Pulmonary Fibrosis Inflammatory impact of IFN-in CD 8 T cell-mediated lung injury is mediated by both Stat 1-dependent and-independent pathways

Aseem Kumar, C. Ramana, J. Durbin, 2015 .

Antiapoptotic Actions of Methyl Gallate on Neonatal Rat Cardiac Myocytes Exposed to H2O2

Aseem Kumar, T. Tai, K. Venkataraman, 2014, Oxidative medicine and cellular longevity.

Cloning and Characterization of the Human Heparanase-1 (HPR1) Gene Promoter ROLE OF GA-BINDING PROTEIN AND Sp1 IN REGULATING HPR1 BASAL PROMOTER ACTIVITY*

J. Parrillo, Aseem Kumar, J. Platt, 2002 .

Salvage Treatment for Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia: Efficacy of Linezolid With or Without Carbapenem

Aseem Kumar, S. Kethireddy, 2010 .

A Review of gastro-retentive drug delivery systems for antidiabetics and its present status

Aseem Kumar, A. Sharma, R. Dutt, 2021 .

Transforming growth factor-beta1 blocks in vitro cardiac myocyte depression induced by tumor necrosis factor-alpha, interleukin-1beta, and human septic shock serum.

Anand Kumar, J. Parrillo, Aseem Kumar, 2007, Critical care medicine.

Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase.

A. Aguzzi, Aseem Kumar, L. Reis, 1995, The EMBO journal.

Expression of intracellular interferon constitutively activates ISGF3 and confers resistance to EMC viral infection.

B. Coulombe, B. Williams, Aseem Kumar, 1996, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Myocardial dysfunction in septic shock: Part II. Role of cytokines and nitric oxide.

J. Parrillo, Aseem Kumar, A. Kumar, 2001, Journal of cardiothoracic and vascular anesthesia.

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

Aseem Kumar, A. Kumar, J. Hiscott, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A multicenter, prospective validation of disseminated intravascular coagulation diagnostic criteria for critically ill patients: Comparing current criteriaGando S, for the Japanese Association for Acute Medicine Disseminated Intravascular Coagulation (JAAM DIC) Study Group (Hokkaido Univ, Sapporo, J

Aseem Kumar, R. Zarychanski, 2007 .

Bioinformatic Comparison of Bacterial Secretomes

Mazen Saleh, Catharine Song, Aseem Kumar, 2009, Genom. Proteom. Bioinform..

Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase.

G. Feng, Aseem Kumar, A. Kumar, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The role of PKR in dsRNA and interferon signal transduction

Aseem Kumar, B. Williams, 1995 .

A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection

Stephen J. Huang, K. Schughart, R. Geffers, 2017, European Respiratory Journal.

The impact of time on the systemic inflammatory response in pneumococcal pneumonia

Aseem Kumar, S. Kethireddy, 2010 .