I. Bigio

J. Mourant, A. Hielscher, I. Bigio, 1997, Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136).

Elastic Scattering Spectroscopy as a Diagnostic Tool for Apoptosis in Cell Cultures

I. Bigio, C. Mulvey, A. Curtis, 2007, IEEE Journal of Selected Topics in Quantum Electronics.

Spectroscopy for the Assessment of Melanomas

I. Bigio, O. A’amar, 2006 .

Measuring absorption coefficients in small volumes of highly scattering media: source-detector separations for which path lengths do not depend on scattering properties.

I J Bigio, J. Mourant, I. Bigio, 1997, Applied optics.

Wavelength-dependent backscattering measurements for quantitative monitoring of apoptosis, part 1: early and late spectral changes are indicative of the presence of apoptosis in cell cultures.

I. Bigio, D. Waxman, C. Mulvey, 2011, Journal of biomedical optics.

Anatomy of the Human Osseous Spiral Lamina and Cochlear Partition Bridge: Relevance for Cochlear Partition Motion

J. Nadol, J. Guinan, I. Bigio, 2020, Journal of the Association for Research in Otolaryngology.

Elucidating the temporal dynamics of optical birefringence changes in crustacean nerves.

Kurt J. Schoener, I. Bigio, A. Badreddine, 2015, Biomedical optics express.

Speckle Holography: a Noninvasive Technique for Imaging Nerve Activity

Kurt J. Schoener, T. Netoff, I. Bigio, 2006 .

Integrated Device for in Vivo Fine Needle Aspiration Biopsy and Elastic Scattering Spectroscopy in Preoperative Thyroid Nodules

Stephanie L. Lee, A. Sauer-Budge, I. Bigio, 2014 .

Noninvasive identification of bladder cancer with subsurface backscattered light

Irving J. Bigio, Judith R. Mourant, Richard L. Conn, 1994, Photonics West - Lasers and Applications in Science and Engineering.

DETERMINATION OF THE CERVICAL SCATTERING SPECTROSCOPY TRANSFORMATION ZONE USING ELASTIC -

J. Mourant, I. Bigio, T. Johnson, 2008 .

Monte Carlo investigations of elastic scattering spectroscopy applied to latex spheres used as tissue phantoms

Irving J. Bigio, Judith R. Mourant, James D. Boyer, 1995, Photonics West.

INTEGRATED OPTICAL TOOLS FOR MINIMALLY INVASIVE DIAGNOSIS AND TREATMENT AT GASTROINTESTINAL ENDOSCOPY.

Satish K. Singh, I. Bigio, E. Rodriguez-Diaz, 2011, Robotics and computer-integrated manufacturing.

Elastic light scattering spectroscopy for the detection of pre-cancer: an overview

I. Bigio, 2009 .

Elastic scattering spectroscopy scanning of sentinel lymph nodes for intraoperative diagnosis of breast cancer metastases

C. Mosse, I. Bigio, M. Falzon, 2008 .

Elastic Light-Scattering Spectroscopy for Discrimination of Benign from Malignant Disease in Thyroid Nodules

Stephanie L. Lee, I. Bigio, E. Rodriguez-Diaz, 2011, Annals of Surgical Oncology.

Diagnosis of tissue pathology with elastic scattering spectroscopy

J. Mourant, I. Bigio, J. Boyer, 1994, Proceedings of LEOS'94.

In vivo applications of diffuse optical spectroscopy and imaging

I. Bigio, S. Fantini, 2016 .

On the Validity of Assumptions to Incorporate Absorption in Monte Carlo Simulations

Katherine W. Calabro, I. Bigio, 2012 .

Polar Nephelometer Based On a Rotational Confocal Imaging Setup for Scattering Measurements from Cells

I. Bigio, J. Castagner, 2006 .

Non-invasive measurement of chemotherapy drug concentrations in tissue: preliminary demonstrations of in vivo measurements.

I J Bigio, J. Mourant, I. Bigio, 1999, Physics in medicine and biology.

Flow arrest intra-arterial delivery of small TAT-decorated and neutral micelles to gliomas

Shaolie S. Hossain, J. Bruce, I. Bigio, 2017, Journal of Neuro-Oncology.

Cerebral hypoperfusion-assisted intra-arterial deposition of liposomes in normal and glioma-bearing rats.

Rajinder P. Singh-Moon, J. Bruce, I. Bigio, 2015, Neurosurgery.

The feasibility of real-time in vivo optical detection of blood–brain barrier disruption with indocyanine green

J. Bruce, I. Bigio, R. Fine, 2012, Journal of Neuro-Oncology.

Optical monitoring of tumor angiogenesis

K. L. Andken, I. Bigio, C. Sheng, 2009, 2009 IEEE 35th Annual Northeast Bioengineering Conference.

An Optical Method for Assessing Angiogenesis: Preliminary Results

I. Bigio, R. Mattrey, Kerry Anderson, 2006 .

Optical pharmacokinetics to assess the permeability of angiogenic neovasculature

J. Mourant, I. Bigio, R. Mattrey, 2002 .

Ultraviolet and visible spectroscopies for tissue diagnostics: fluorescence spectroscopy and elastic-scattering spectroscopy.

J. Mourant, I. Bigio, 1997, Physics in medicine and biology.

Optical Biopsies and Microscopic Techniques II

Herbert Schneckenburger, Warren S. Grundfest, Irving J. Bigio, 1996 .

A Partially Supervised Bayesian Image Classification Model with Applications in Diagnosis of Sentinel Lymph Node Metastases in Breast Cancer

T. Fearn, C. Mosse, I. Bigio, 2017, 1712.09853.

Fast and reliable determination of Escherichia coli susceptibility to antibiotics: Infrared microscopy in tandem with machine learning algorithms

I. Bigio, A. Salman, U. Sharaha, 2019, Journal of biophotonics.

Real-time imaging of action potentials in nerves using changes in birefringence

I. Bigio, A. Badreddine, Tomas Jordan, 2016, Biomedical optics express.

Non-invasive measurement of chemotherapy drug concentrations in tissue: preliminary demonstrations of in vivo measurements.

J. Mourant, I. Bigio, T. Johnson, 1999, Physics in medicine and biology.

Real-time hemodynamic response and mitochondrial function changes with intracarotid mannitol injection

Rajinder P. Singh-Moon, J. Bruce, I. Bigio, 2014, Brain Research.

Molecular second- and third-order polarizabilities from measurements of second-harmonic generation in gases

I. Bigio, J. Ward, 1975 .

Detection of antibiotic resistant Escherichia Coli bacteria using infrared microscopy and advanced multivariate analysis.

I. Bigio, A. Salman, U. Sharaha, 2017, The Analyst.

Low-frequency (20–400 cm−1) vibrational spectra of N-methylacetamide in the liquid state

I. Bigio, O. Nielsen, J. Berquier, 1986 .

Experimental and computational study of N-methylacetamide

I. Bigio, P. Christiansen, O. Skovgaard, 1986 .

Temporal Variations of Skin Pigmentation in C57Bl/6 Mice Affect Optical Bioluminescence Quantitation

Katherine W. Calabro, I. Bigio, T. Krucker, 2010, Molecular Imaging and Biology.

Raman Spectroscopy of Bacillus megaterium Using an Optical Multi-channel Analyzer

I. Bigio, S. Layne, 1986 .

Safety, feasibility, and optimization of intra-arterial mitoxantrone delivery to gliomas

Rajinder P. Singh-Moon, J. Bruce, I. Bigio, 2016, Journal of Neuro-Oncology.

Intra-arterial Mitoxantrone Delivery in Rabbits: An Optical Pharmacokinetic Study

Shailendra Joshi, Roberto Reif, Robert L Fine, 2011, Neurosurgery.

The future of medical diagnostics: review paper

Hugh Barr, Andreas Leunig, Nicholas Stone, 2011, Head & neck oncology.

Attainment of the theoretical minimum input power for injection locking of an unstable-resonator KrF laser.

I. Bigio, M. Slatkine, 1981, Optics letters.

Workshop on imaging science development for cancer prevention and preemption.

G. McLennan, C. Tempany, S. Lam, 2006, Cancer biomarkers : section A of Disease markers.

Wavelength-dependent backscattering measurements for quantitative monitoring of apoptosis, part 2: early spectral changes during apoptosis are linked to apoptotic volume decrease.

Irving J Bigio, Kexiong Zhang, I. Bigio, 2011, Journal of biomedical optics.

Wavelength-dependent backscattering measurements for quantitative real-time monitoring of apoptosis in living cells.

Irving J Bigio, I. Bigio, Carly A Sherwood, 2009, Journal of biomedical optics.

Transient cerebral hypoperfusion assisted intraarterial cationic liposome delivery to brain tissue

Irving J. Bigio, Shailendra Joshi, Jeffrey N. Bruce, 2014, Journal of Neuro-Oncology.

Optical Spectroscopy as a Method for Skin Cancer Risk Assessment

I. Bigio, D. Leffell, E. Rodriguez-Diaz, 2019, Photochemistry and photobiology.

Analysis of changes in reflectance measurements on biological tissues subjected to different probe pressures.

Katherine W. Calabro, Roberto Reif, Irving J Bigio, 2008, Journal of biomedical optics.

Elastic scattering spectroscopy for early detection of breast cancer: partially supervised Bayesian image classification of scanned sentinel lymph nodes

Tom Fearn, Ying Zhu, Stephen G Bown, 2018, Journal of biomedical optics.

Subnanosecond multi-gigawatt CO/sub 2/ laser

Irving J. Bigio, Tsutomu Shimada, Igor Pogorelsky, 1995 .

High‐power visible laser action in neutral atomic fluorine

Irving J. Bigio, I. Bigio, R. F. Begley, 1976 .

Optimizing the probe geometry of elastic scattering spectroscopy for the diagnosis of prostate cancer

I. Bigio, M. Hirsch, O. A’amar, 2004 .

Elastic scattering spectroscopy for detection of prostate cancer: preliminary feasibility study

Irving J. Bigio, Michelle S. Hirsch, I. Bigio, 2003, European Conference on Biomedical Optics.

Efficient phase conjugation of an ultraviolet XeF laser beam by stimulated Brillouin scattering.

I. Bigio, R. Fisher, B. Feldman, 1982, Optics letters.

Multimodal assessment of spatial distribution of drug-tracer uptake by brain tissue after intra-arterial injections

Irving J. Bigio, Mei Wang, Rajinder Singh-Moon, 2014, Photonics West - Biomedical Optics.

Microwave absorption spectroscopy of DNA

T. R. Gosnell, J. Saffer, I. Bigio, 1993, Biopolymers.

Biomedical applications of laser technology at Los Alamos

Irving J. Bigio, Thomas R. Loree, I. Bigio, 1991, Other Conferences.

Optical Biopsy

Irving J. Bigio, Judith R. Mourant, J. Mourant, 2020, Definitions.

Towards minimally-invasive, quantitative assessment of chronic kidney disease using optical spectroscopy

Mostafa E. Belghasem, I. Bigio, D. Salant, 2019, Scientific Reports.

Elastic scattering spectroscopy in the diagnosis of pigmented lesions: comparison with clinical and histopathological diagnosis

Irving J. Bigio, Stephen G. Bown, Marco Novelli, 2003, European Conference on Biomedical Optics.

Confocal light absorption and scattering spectroscopic microscopy.

Irving Itzkan, Steven D Freedman, Edward Vitkin, 2007, Applied optics.

Optical method for real-time monitoring of drug concentrations facilitates the development of novel methods for drug delivery to brain tissue.

Shailendra Joshi, Roberto Reif, Irving J Bigio, 2007, Journal of biomedical optics.

Elastic Scattering Spectroscopy as an Optical Marker of Inflammatory Bowel Disease Activity and Subtypes

Irving J. Bigio, Eladio Rodriguez-Diaz, Satish K. Singh, 2014, Inflammatory bowel diseases.

Noninvasive, in-situ measurement of drug concentrations in tissue using optical spectroscopy.

J. Mourant, I. Bigio, G. Los, 1999, Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology.

Noninvasive in vivo optical assessment of blood brain barrier permeability and brain tissue drug deposition in rabbits.

I. Bigio, S. Joshi, Mei Wang, 2012, Journal of biomedical optics.

Inconsistent blood brain barrier disruption by intraarterial mannitol in rabbits: implications for chemotherapy

Irving J. Bigio, Shailendra Joshi, Roberto Reif, 2011, Journal of Neuro-Oncology.

High-efficiency pulsed 10.6-Mu m phase-conjugate reflection via degenerate four-wave mixing.

R A Fisher, I J Bigio, I. Bigio, 1978, Optics letters.

Quantitative birefringence microscopy for imaging the structural integrity of CNS myelin following circumscribed cortical injury in the rhesus monkey

Douglas L. Rosene, Irving J. Bigio, Veronica Go, 2021, Neurophotonics.

Birefringence Microscopy for Label-Free Imaging of Myelin Degeneration in Brain Sections

I. Bigio, Nathan Blanke, 2021, Biophotonics Congress 2021.

Spatial mapping of drug delivery to brain tissue using hyperspectral spatial frequency-domain imaging

Shailendra Joshi, Rajinder P Singh-Moon, Darren M Roblyer, 2014, Journal of biomedical optics.

Injection-locking unstable resonator excimer lasers

Irving J. Bigio, I. Bigio, M. Slatkine, 1983 .

Narrow band tuning with small long pulse excimer lasers

D. E. Watkins, I. Bigio, N. Kurnit, 1985 .

Artificial Intelligence-Based Assessment of Colorectal Polyp Histology by Elastic-Scattering Spectroscopy

Satish K. Singh, I. Bigio, L. Jepeal, 2021, Digestive Diseases and Sciences.

Confocal light absorption and scattering spectroscopic microscopy monitors organelles in live cells with no exogenous labels

Irving Itzkan, Steven D Freedman, Edward Vitkin, 2007, Proceedings of the National Academy of Sciences.

Polar nephelometer based on a rotational confocal imaging setup.

Irving J Bigio, I. Bigio, Jean-Luc Castagner, 2006, Applied optics.

Elastic and quasi-elastic scattering from cells and small structures

I. Bigio, S. Fantini, 2016 .

Detection of Extended-Spectrum β-Lactamase-Producing Escherichia coli Using Infrared Microscopy and Machine-Learning Algorithms.

I. Lapidot, I. Bigio, A. Salman, 2019, Analytical chemistry.

Generation of high brightness 1,06-µm pulses by compression of a chirped seed in a Nd:YAG regenerative amplifier

R. F. Harrison, I. Bigio, N. Kurnit, 1989 .

Proposal for a study of laser acceleration of electrons using micrograting structures at ATF (Phase 1)

R. Palmer, I. Bigio, K. McDonald, 1989 .

Ultrafast optical property map generation using lookup tables.

Sylvain Gioux, Joseph Angelo, Irving J Bigio, 2016, Journal of biomedical optics.

Spectroscopy of the amide-I modes of acetanilide

A. Scott, I. Bigio, C. Johnston, 1990 .

In-vivo detection of pre-cancerous changes in Barrett's esophagus using elastic scattering spectroscopy (ESS)

Stephen G. Bown, Irving J. Bigio, Kristie Johnson, 2005, European Conference on Biomedical Optics.

mTHPC pharmacokinetics following topical administration

Stefan Andersson-Engels, Katarina Svanberg, Eleni Alexandratou, 2006, SPIE BiOS.

Scanning elastic scattering spectroscopy detects metastatic breast cancer in sentinel lymph nodes.

Katherine W. Calabro, Tom Fearn, Gabrijela Kocjan, 2010, Journal of biomedical optics.

Elastic-scattering spectroscopy for quantitative measurement of chemotherapy and PDT drug concentrations in vivo

Irving J. Bigio, Judith R. Mourant, Gerrit Los, 1999, European Conference on Biomedical Optics.

Large-volume high-pressure CO 2 laser for ultrashort pulse amplification

R. F. Harrison, I. Bigio, N. Kurnit, 1988 .

Preoperative Discrimination of Benign from Malignant Disease in Thyroid Nodules With Indeterminate Cytology Using Elastic Light-Scattering Spectroscopy

Jennifer E. Rosen, Hyunsuk Suh, Nicholas J. Giordano, 2014, IEEE Transactions on Biomedical Engineering.

Comparison between ultraviolet-visible and near-infrared elastic scattering spectroscopy of chemically induced melanomas in an animal model.

Irving J Bigio, I. Bigio, O. A’amar, 2004, Journal of biomedical optics.

Correction of fluorescence spectra using data from elastic scattering spectroscopy and a modified Beer's law

I. Bigio, O. A’amar, 2002 .

Elastic scattering spectroscopy for detection of cancer risk in Barrett's esophagus: experimental and clinical validation of error removal by orthogonal subtraction for increasing accuracy.

Tom Fearn, Stephen G Bown, Irving J Bigio, 2009, Journal of biomedical optics.

Elastic scattering spectroscopy for the diagnosis of colonic lesions: initial results of a novel optical biopsy technique.

Stephen G Bown, Irving J Bigio, Laurence B Lovat, 2006, Gastrointestinal Endoscopy.

Endoscopic histological assessment of colonic polyps by using elastic scattering spectroscopy.

Satish K. Singh, I. Bigio, M. O'brien, 2015, Gastrointestinal endoscopy.

Optical scattering as an early marker of apoptosis during chemotherapy and antiangiogenic therapy in murine models of prostate and breast cancer

I. Bigio, D. Roblyer, D. Waxman, 2021, European Conference on Biomedical Optics.

Towards minimally-invasive, quantitative assessment of chronic kidney disease using optical spectroscopy

Mostafa E. Belghasem, I. Bigio, D. Salant, 2019, Scientific Reports.

Spectral classifier design with ensemble classifiers and misclassification-rejection: application to elastic-scattering spectroscopy for detection of colonic neoplasia.

Irving J Bigio, Eladio Rodriguez-Diaz, David A Castanon, 2011, Journal of biomedical optics.

Optical biopsy using elastic scattering spectroscopy can detect high grade dysplasia and cancer in Barrett's esophagus

Irving J. Bigio, Stephen G. Bown, Novelli, 2004 .

Elastic scattering spectroscopy as a diagnostic for tissue pathologies

Irving J. Bigio, Judith R. Mourant, Tamara M. Johnson, 1994 .

Gender variations in the optical properties of skin in murine animal models.

Katherine W. Calabro, Thomas Krucker, Irving J Bigio, 2011, Journal of biomedical optics.

A NOVEL OPTICAL BIOPSY TECHNIQUE USING ELASTIC SCATTERING SPECTROSCOPY FOR DYSPLASIA AND CANCER IN BARRETT'S ESOPHAGUS.

I. Bigio, L. Lovat, M. Novelli, 2000 .

Phase conjugation

H. Haus, E. Ippen, J. Whinnery, 1982 .

Measurement of the hyperpolarizability ratio X_{y y y y}(-2ω;0,ω,ω)/X_{y y x x}(-2ω;0,ω,ω) for the inert gases

I. Bigio, J. Ward, 1974 .

Electric-field induced harmonic generation as a probe of the focal region of a laser beam.

I. Bigio, J. Ward, R. Finn, 1975, Applied optics.

Variations in the optical scattering properties of skin in murine animal models

Katherine W. Calabro, Irving J. Bigio, Thomas Krucker, 2011, BiOS.

Studying cells in vivo with confocal light absorption and scattering spectroscopy (CLASS)

Hui Fang, Steven D. Freedman, Irving J. Bigio, 2007, SPIE BiOS.

Particle sizing with a fast polar nephelometer.

I. Bigio, J. Castagner, 2007, Applied optics.

Determination of the minimum x‐ray flux for effective preionization of an XeCl laser

I. Bigio, C. Tallman, 1983 .

Preionization of pulsed gas lasers by radioactive source

I. Bigio, 1978 .

Gastrointestinal Cancer Surveillance by Optical Sensing

Satish K. Singh, I. Bigio, 2007, Clinical Cancer Research.

Quenching of backward stimulated Raman scattering by broadband forward Raman radiation.

I. Bigio, M. Slatkine, 1984, Optics letters.

Diagnosis of breast cancer using elastic-scattering spectroscopy: preliminary clinical results.

S. Lakhani, I. Bigio, S. Bown, 2000, Journal of biomedical optics.

Elastic scattering spectroscopy accurately detects high grade dysplasia and cancer in Barrett’s oesophagus

T Fearn, T. Fearn, S. Davies, 2005, Gut.

Noninvasive in vivo optical assessment of blood brain barrier permeability and brain tissue drug deposition in rabbits.

I. Bigio, S. Joshi, Mei Wang, 2012, Journal of Biomedical Optics.

Diffuse polarization spectroscopy on tissue phantoms and biological cell suspensions

Irving J. Bigio, Judith R. Mourant, Andreas H. Hielscher, 1996, European Conference on Biomedical Optics.

Injection-Locked, Unstable Resonator Dye Laser

I. Bigio, 1978 .

Effective saturable absorber for KrF lasers

I. Bigio, S. Thomas, 1986 .

The Vibrational Soliton: an Experimental Overview

I. Bigio, 1987 .

Experiments for the Detection of Solitons in Biopolymers

I. Bigio, C. Johnston, S. Layne, 1985 .

Transient fluorescence in synchronously dividing Escherichia coli.

P. Lomdahl, I. Bigio, S. Layne, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Endoscopic histological assessment of colonic polyps by using elastic scattering spectroscopy.

Satish K. Singh, I. Bigio, M. O'brien, 2015, Gastrointestinal endoscopy.

Elastic scattering spectroscopy for intraoperative determination of sentinel lymph node status in the breast.

Stephen G Bown, Irving J Bigio, Mary Falzon, 2004, Journal of biomedical optics.

Liposome size and charge optimization for intraarterial delivery to gliomas

Shaolie S. Hossain, Rajinder P. Singh-Moon, J. Bruce, 2016, Drug Delivery and Translational Research.

Elastic Scattering Spectroscopy as an Optical Marker of Inflammatory Bowel Disease Activity and Subtypes

Satish K. Singh, I. Bigio, M. O'brien, 2014, Inflammatory bowel diseases.

Optical scanning for rapid intraoperative diagnosis of sentinel node metastases in breast cancer

C. Mosse, I. Bigio, Martin R. Austwick, 2010, The British journal of surgery.

Can Scattering Spectroscopy Detect Disease Earlier than Histopathology

I. Bigio, 2010 .

A Fiber Optic Probe Design to Measure Depth- Limited Optical Properties In-vivo with Low- Coherence Enhanced Backscattering (lebs) Spectroscopy References and Links

Vadim Backman, Vladimir Turzhitsky, Nikhil N. Mutyal, 2022 .

Optical biopsy using elastic scattering spectroscopy can detect dysplasia and cancer in Barrett's oesophagus

Novelli, I. Bigio, L. Lovat, 2005 .

Diagnosis of dysplasia in Barrett's oesophagus with in-situ elastic-scattering spectroscopy

Irving J. Bigio, Stephen G. Bown, David Christopher O. Pickard, 2000, European Conference on Biomedical Optics.

Optical Biopsy and Tissue Optics

R. Steiner, I. Bigio, G. Mueller, 2000 .

Detection of gastrointestinal cancer by elastic scattering and absorption spectroscopies with the Los Alamos Optical Biopsy System

Judith R. Mourant, Irving J. Bigio, Tamara M. Johnson, 1995, Photonics West.

Influence of the phase function in generalized diffuse reflectance models: review of current formalisms and novel observations

Katherine W. Calabro, Irving J. Bigio, I. Bigio, 2014, Journal of biomedical optics.