P. Orlean

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Identification of pathogenic fungi with an optoelectronic nose.

Jon R. Askim, K. Suslick, Yinan Zhang, 2014, The Analyst.

Mitotic exit kinase Dbf2 directly phosphorylates chitin synthase Chs2 to regulate cytokinesis in budding yeast

Kuang-Jung Chang, P. Orlean, E. Bi, 2012, Molecular biology of the cell.

A carbon-13 nuclear magnetic resonance spectroscopic study of inter-proton pair order parameters: a new approach to study order and dynamics in phospholipid membrane systems.

E. Oldfield, P. Orlean, J. Urbina, 1998, Biophysical journal.

Glycoprotein biosynthesis in yeast

P. Orlean, A. Herscovics, P Orlean, 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Analysis of glycoproteins from Saccharomyces cerevisiae.

P. Orlean, C. Albright, M. Kuranda, 1991, Methods in enzymology.

Two chitin synthases in Saccharomyces cerevisiae.

P. Orlean, 1987, The Journal of biological chemistry.

Deficiencies in the endoplasmic reticulum (ER)-membrane protein Gab1p perturb transfer of glycosylphosphatidylinositol to proteins and cause perinuclear ER-associated actin bar formation.

P. Orlean, E. Bi, A. Farewell, 2004, Molecular biology of the cell.

Chapter 6 phosphoethanolamine addition to glycosylphosphatidylinositols

P. Orlean, 2009 .

In vivo characterization of the GPI assembly defect in yeast mcd4-174 mutants and bypass of the Mcd4p-dependent step in mcd4Delta cells.

P. Orlean, C. Taron, Barbara W Taron, 2007, FEMS yeast research.

Priming and elongation of chitin chains: Implications for chitin synthase mechanism

P. Orlean, Danielle Funai, 2018, Cell surface.

Inositol acylation of a potential glycosyl phosphoinositol anchor precursor from yeast requires acyl coenzyme A.

P. Orlean, L. C. Costello, 1992, The Journal of biological chemistry.

Temperature-sensitive Yeast GPI Anchoring Mutants gpi2 and gpi3 Are Defective in the Synthesis of N-Acetylglucosaminyl Phosphatidylinositol.

J. Fassler, P. Orlean, W. Gray, 1995, The Journal of Biological Chemistry.

Comparative importance in vivo of conserved glutamate residues in the EX7E motif retaining glycosyltransferase Gpi3p, the UDP-GlcNAc-binding subunit of the first enzyme in glycosylphosphatidylinositol assembly.

P. Orlean, A. Menon, S. Vainauskas, 2003, European journal of biochemistry.

Saccharomyces cerevisiae sec59 cells are deficient in dolichol kinase activity.

P. Orlean, L. Heller, W. Adair, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Human Smp3p Adds a Fourth Mannose to Yeast and Human Glycosylphosphatidylinositol Precursors in Vivo*

P. Orlean, C. Taron, P. Colussi, 2004, Journal of Biological Chemistry.

Ynl038wp (Gpi15p) is the Saccharomyces cerevisiae homologue of human Pig‐Hp and participates in the first step in glycosylphosphatidylinositol assembly

P. Orlean, B. C. Yan, B. Westfall, 2001, Yeast.

3 Biogenesis of Yeast Wall and Surface Components

P. Orlean, 1997 .

Synthesis of an O-glycosylated cell surface protein induced in yeast by α factor

P. Orlean, M. Watzele, W. Tanner, 1986 .

The Saccharomyces cerevisiae DPM1 gene encoding dolichol-phosphate-mannose synthase is able to complement a glycosylation-defective mammalian cell line

J. Sambrook, M. Gething, P. Orlean, 1990, Molecular and cellular biology.

Enzymes that recognize dolichols participate in three glycosylation pathways and are required for protein secretion.

P. Orlean, 1992, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Uptake of radiolabeled GlcNAc into Saccharomyces cerevisiae via native hexose transporters and its in vivo incorporation into GPI precursors in cells expressing heterologous GlcNAc kinase

E. Boles, P. Orlean, John J Scarcelli, 2012, FEMS yeast research.

The Saccharomyces cerevisiae DPM 1 Gene Encoding Dolichol-Phosphate-Mannose Synthase Is Able To Complement a Glycosylation-Defective Mammalian Cell Line

M. Gething, P. Orlean, P. Beck, 2022 .

Congenital disorders of glycosylation caused by defects in mannose addition during N-linked oligosaccharide assembly.

P. Orlean, 2000, The Journal of clinical investigation.

Saccharomyces cerevisiae mating pheromones specifically inhibit the synthesis of proteins destined to be N-glycosylated.

P. Orlean, W. Tanner, A. Haselbeck, 1984, European journal of biochemistry.

2-Acylamido Analogues of N-Acetylglucosamine Prime Formation of Chitin Oligosaccharides by Yeast Chitin Synthase 2

P. Orlean, E. Bi, Y. Oh, 2014, The Journal of Biological Chemistry.

Gpi1, a Saccharomyces cerevisiae Protein That Participates in the First Step in Glycosylphosphatidylinositol Anchor Synthesis*

P. Orlean, S. Leidich, 1996, The Journal of Biological Chemistry.

Dolichol phosphate mannose synthase is required in vivo for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and N glycosylation of protein in Saccharomyces cerevisiae

P. Orlean, 1990, Molecular and cellular biology.

Architecture and Biosynthesis of the Saccharomyces cerevisiae Cell Wall

P. Orlean, 2012, Genetics.

A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis.

P. Orlean, S. Leidich, D. Drapp, 1994, The Journal of biological chemistry.

Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose.

P. Orlean, C. Taron, S. Grimme, 2000, Molecular biology of the cell.

Biosynthesis of Glycosylphosphatidylinositols in Mammals and Unicellular Microbes

P. Orlean, R. Schmidt, A. Tiede, 1999, Biological chemistry.

The action of 2-deoxy-D-glucose on the incorporation of glucose into (1----3)-beta-glucan in stationary phase cultures of Candida albicans.

P. Orlean, E. F. Gale, F. Wayman, 1984, Journal of general microbiology.

(1,3)-beta-D-Glucan synthase from budding and filamentous cultures of the dimorphic fungus Candida albicans.

P. Orlean, 1982, European journal of biochemistry.

The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG‐A, PIG‐H, PIG‐C and GPI1

P. Orlean, R. Watanabe, C. Taron, 1998, The EMBO journal.

Thematic review series: Lipid Posttranslational Modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids Published, JLR Papers in Press, March 14, 2007.

Anant K. Menon, P. Orlean, A. Menon, 2007, Journal of Lipid Research.

Deficiencies in the essential Smp3 mannosyltransferase block glycosylphosphatidylinositol assembly and lead to defects in growth and cell wall biogenesis in Candida albicans.

P. Orlean, C. Taron, P. Colussi, 2004, Microbiology.

The Essential Schizosaccharomyces pombe gpi1+ Gene Complements a Bakers' Yeast GPI Anchoring Mutant and is Required for Efficient Cell Separation

P. Orlean, P. Colussi, 1997, Yeast.

Isolation and characterization of yeast glycosylphosphatidylinositol anchoring mutants.

P. Orlean, S. Leidich, D. Drapp, 1995, Methods in enzymology.

Correction of a defect in mammalian GPI anchor biosynthesis by a transfected yeast gene.

J. Sambrook, P. Orlean, E. Yeh, 1990, Science.

Cloning and sequencing of the yeast gene for dolichol phosphate mannose synthase, an essential protein.

P. Orlean, P. Robbins, C. Albright, 1988, The Journal of biological chemistry.

Topography of glycosylation in yeast: characterization of GDPmannose transport and lumenal guanosine diphosphatase activities in Golgi-like vesicles.

P. Orlean, P. Robbins, C. Abeijon, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Human and Saccharomyces cerevisiae dolichol phosphate mannose synthases represent two classes of the enzyme, but both function in Schizosaccharomyces pombe.

P. Orlean, J. Mack, C. Taron, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Dolichol phosphate mannose synthase from the filamentous fungus Trichoderma reesei belongs to the human and Schizosaccharomyces pombe class of the enzyme.

M. Penttilä, P. Orlean, M. Saloheimo, 2000, Glycobiology.

Chemical and numerical taxonomy of strains received as Gordona aurantiaca

M. Collins, D. Minnikin, P. Orlean, 1978 .

Yeast Ras Regulates the Complex that Catalyzes the First Step in GPI-Anchor Biosynthesis at the ER

D. E. Levin, P. Orlean, H. Riezman, 2004, Cell.

Analysis of a cellulose synthase catalytic subunit from the oomycete pathogen of crops Phytophthora capsici

P. Orlean, V. Srivastava, V. Bulone, 2020, Cellulose.

The GPI1 homologue from Plasmodium falciparum complements a Saccharomyces cerevisiae GPI1 anchoring mutant.

R. Schwarz, P. Orlean, T. Kinoshita, 2002, Molecular and biochemical parasitology.

MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast.

S. Reed, S. Emr, P. Orlean, 1999, Molecular biology of the cell.

Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants.

P. Orlean, R. Schmidt, C. Taron, 1998, The Biochemical journal.

Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

Hong Sun, Stewart T. Cole, Douglas A. Mitchell, 2014, Journal of medicinal chemistry.

Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'-triphosphate identifies gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis.

P. Orlean, A. Menon, D. Rancour, 2000, The Biochemical journal.

Structure of the yeast endoplasmic reticulum: Localization of ER proteins using immunofluorescence and immunoelectron microscopy

D Botstein, D. Botstein, J. Mulholland, 1991, Yeast.

Saccharomyces cerevisiae Ybr004c and its human homologue are required for addition of the second mannose during glycosylphosphatidylinositol precursor assembly

P. Orlean, C. Taron, A. Fabre, 2005, The FEBS journal.

Isolation of temperature-sensitive yeast GPI-anchoring mutants.

P. Orlean, P. Colussi, S. Leidich, 1994, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Apparent inhibition of glycoprotein synthesis by S.cerevisiae mating pheromones

P. Orlean, W. Tanner, Elisabeth Arnold, 1985, FEBS letters.

Saccharomyces cerevisiae α‐factor prevents formation of glycoproteins in a cells

P. Orlean, W. Tanner, G. Seebacher, 1983 .

A 13-amino acid peptide in three yeast glycosyltransferases may be involved in dolichol recognition.

P. Orlean, P. Robbins, C. Albright, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Gpi19, the Saccharomyces cerevisiae Homologue of Mammalian PIG-P, Is a Subunit of the Initial Enzyme for Glycosylphosphatidylinositol Anchor Biosynthesis

D. E. Levin, P. Orlean, Martin J. Romeo, 2005, Eukaryotic Cell.

The Essential Schizosaccharomyces pombe gpi1+ Gene Complements a Bakers' Yeast GPI Anchoring Mutant and is Required for Efficient Cell Separation

P. Orlean, P. Colussi, 1997, Yeast.

Saccharomyces cerevisiae alpha-factor prevents formation of glycoproteins in a cells.

P. Orlean, W. Tanner, G. Seebacher, 1983, FEBS Letters.

Isoniazid Susceptibility as a Criterion for the Differentiation of Mycobacterial Species from Other Mycolic Acid-Containing Taxa

D. Minnikin, P. Orlean, M. Goodfellow, 1978 .

The Essential Smp3 Protein Is Required for Addition of the Side-branching Fourth Mannose during Assembly of Yeast Glycosylphosphatidylinositols*

P. Orlean, C. Taron, P Orlean, 2001, The Journal of Biological Chemistry.

Glycogen synthesis by cell-free extracts from the dimorphic yeast Candida albicans

P. Orlean, 2004, Antonie van Leeuwenhoek.