Lars Ruddigkeit

发表

Chemical space as a source for new drugs

Lorenz C. Blum, J. Reymond, R. V. Deursen, 2010 .

Considerations on the Drug-Like Chemical Space

J. Reymond, Lars Ruddigkeit, M. Awale, 2014 .

The Chemical Space of Flavours

J. Reymond, Lars Ruddigkeit, 2014 .

Identifying Lysophosphatidic Acid Acyltransferase β (LPAAT‐β) as the Target of a Nanomolar Angiogenesis Inhibitor from a Phenotypic Screen Using the Polypharmacology Browser PPB2

J. Reymond, Lars Ruddigkeit, J. Lorens, 2018, ChemMedChem.

Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation.

A. Stocker, K. Pallauf, G. Rimbach, 2014, Free radical biology & medicine.

Expanding the fragrance chemical space for virtual screening

Jean-Louis Reymond, Mahendra Awale, Lars Ruddigkeit, 2014, Journal of Cheminformatics.

Chemogenomic profiling provides insights into the limited activity of irreversible EGFR Inhibitors in tumor cells expressing the T790M EGFR resistance mutation.

Martin Peifer, Daniel Rauh, Lars Ruddigkeit, 2010, Cancer research.

Enumeration of 166 Billion Organic Small Molecules in the Chemical Universe Database GDB-17

Jean-Louis Reymond, Ruud van Deursen, Lars Ruddigkeit, 2012, J. Chem. Inf. Model..

The enumeration of chemical space

Lars Ruddigkeit, Lorenz C. Blum, Jean‐Louis Reymond, 2012 .

Visualization and Virtual Screening of the Chemical Universe Database GDB-17

Jean-Louis Reymond, Lars Ruddigkeit, Lorenz C. Blum, 2013, J. Chem. Inf. Model..