M. Foroozesh

发表

Insights on Cytochrome P450 Enzymes and Inhibitors Obtained Through QSAR Studies

J. Sridhar, Jiawang Liu, M. Foroozesh, 2012, Molecules.

Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignancies

Jungang Chen, M. Foroozesh, Z. Qin, 2019, Oncogenesis.

7-Ethynylcoumarins: selective inhibitors of human cytochrome P450s 1A1 and 1A2.

J. Sridhar, Jiawang Liu, M. Foroozesh, 2012, Chemical research in toxicology.

Identification of CYP 2A6 inhibitors in an effort to mitigate the harmful effects of the phytochemical nicotine

J. Sridhar, M. Foroozesh, M. Bratton, 2021, Journal of cancer metastasis and treatment.

Metabolism-based polycyclic aromatic acetylene inhibition of CYP1B1 in 10T1/2 cells potentiates aryl hydrocarbon receptor activity.

M. Foroozesh, C. Jefcoate, D. L. Alexander, 1999, Toxicology and applied pharmacology.

Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date

J. Sridhar, Jiawang Liu, M. Foroozesh, 2017, Molecules.

Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.

H. Yamazaki, M. Foroozesh, T. Shimada, 2013, Chemical research in toxicology.

The sphingosine kinase 2 inhibitor ABC294640 displays anti‐non‐small cell lung cancer activities in vitro and in vivo

M. Foroozesh, Z. Qin, Charles D Smith, 2018, International journal of cancer.

Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl Ether

M. Foroozesh, P. Hollenberg, Alecia M. Mccall, 2008, Drug Metabolism and Disposition.

Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.

H. Yamazaki, M. Foroozesh, T. Shimada, 2010, Chemical research in toxicology.

Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic activity.

H. Yamazaki, M. Foroozesh, T. Shimada, 2008, Chemical research in toxicology.

A review of ceramide analogs as potential anticancer agents.

Jiawang Liu, M. Foroozesh, B. Beckman, 2013, Future medicinal chemistry.

Anticancer targets in the ceramide signaling pathway

Jiawang Liu, M. Foroozesh, B. Beckman, 2010 .

Metabolic fate of the Ah receptor ligand 6-formylindolo[3,2-b]carbazole.

M. Foroozesh, A. Rannug, U. Rannug, 2004, Chemico-biological interactions.

Cytochrome P450 Family 1 Inhibitors and Structure-Activity Relationships

J. Sridhar, Jiawang Liu, M. Foroozesh, 2013, Molecules.

DESIGN AND SYNTHESIS OF DIBENZYLFURAN BASED ETHER AND ESTER DERIVATIVES AS POTENTIAL P450 INHIBITORS.

J. Sridhar, M. Foroozesh, Navneet Goyal, 2018, Journal of undergraduate chemistry research.

INACTIVATION OF CYTOCHROME P 450 S 2 B 1 , 2 B 4 , 2 B 6 , AND 2 B 11 BY ARYLALKYNES

M. Foroozesh, J. Halpert, P. Hollenberg, 1997 .

Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1)

J. Sridhar, Jiawang Liu, M. Foroozesh, 2016, Expert opinion on therapeutic patents.

Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme.

Kevin E. Riley, J. Sridhar, Jiawang Liu, 2017, Drug metabolism letters.

In silico studies of polyaromatic hydrocarbon inhibitors of cytochrome P450 enzymes 1A1, 1A2, 2A6, and 2B1.

J. Sridhar, Jiawang Liu, M. Foroozesh, 2010, Chemical research in toxicology.

Release of iron from ferritin by aqueous extracts of cigarette smoke.

W. Pryor, M. Foroozesh, J. J. Moreno, 1992, Chemical research in toxicology.

Novel anti-viability ceramide analogs: design, synthesis, and structure-activity relationship studies of substituted (S)-2-(benzylideneamino)-3-hydroxy-N-tetradecylpropanamides.

Jiawang Liu, M. Foroozesh, B. Beckman, 2010, Bioorganic & medicinal chemistry.

Aryl acetylene inhibitors for cytochrome P450-based monooxygenase isozymes

J. Mague, M. Foroozesh, N. Hopkins, 1997 .

Developing new ceramide analogs and identifying novel sphingolipid controlled genes against a virus-associated lymphoma.

Jungang Chen, Jiawang Liu, M. Foroozesh, 2020, Blood.

Inhibition of Cytochrome P450 6D1 by Alkynylarenes, Methylenedioxyarenes, and Other Substituted Aromatics

M. Foroozesh, T. Alefantis, N. Hopkins, 2000 .

Antimycobacterial activities of dehydrocostus lactone and its oxidation products.

N. H. Fischer, M. Foroozesh, S. Franzblau, 1998, Journal of natural products.

Coumarins and P450s, Studies Reported to-Date

J. Sridhar, Jiawang Liu, M. Foroozesh, 2019, Molecules.

Inactivation of cytochrome P450s 2B1, 2B4, 2B6, and 2B11 by arylalkynes.

M. Foroozesh, J. Halpert, P. Hollenberg, 1997, Drug metabolism and disposition: the biological fate of chemicals.

A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2.

Ming Zhao, Jiawang Liu, M. Foroozesh, 2015, Journal of medicinal chemistry.

Biosynthetic studies of bithiophenes in hairy root cultures of tagetes patula using 13C-labeled acetates

N. H. Fischer, M. Foroozesh, N. Fischer, 1991 .

Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1.

Ming Zhao, J. Sridhar, Jiawang Liu, 2013, Journal of medicinal chemistry.

Suicide inhibitors of cytochrome P450 1A1 and P450 2B1.

M. Foroozesh, N. Hopkins, W. Alworth, 1992, Biochemical pharmacology.

3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells.

Ming Zhao, Jiawang Liu, M. Foroozesh, 2014, Bioorganic & medicinal chemistry.

Acute toxicity evaluation of a novel ceramide analog for the treatment of breast cancer

M. Foroozesh, Muralidharan Anbalagan, R. Hooks, 2021, Toxicology reports.

Inhibition of breast tumor growth in mice after treatment with ceramide analog 315

Jiawang Liu, M. Foroozesh, Muralidharan Anbalagan, 2018, Anti-cancer drugs.

Novel d-erythro N-octanoyl sphingosine analogs as chemo- and endocrine-resistant breast cancer therapeutics

Jiawang Liu, M. Foroozesh, B. Beckman, 2010, Cancer Chemotherapy and Pharmacology.

Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.

Jiawang Liu, M. Foroozesh, M. Burow, 2009, Journal of medicinal chemistry.

Cytochrome P450 Family 1 Inhibitors and Structure-Activity Relationships

J. Sridhar, Jiawang Liu, M. Foroozesh, 2013, Molecules.

Development of flavone propargyl ethers as potent and selective inhibitors of cytochrome P450 enzymes 1A1 and 1A2.

J. Sridhar, Jiawang Liu, M. Foroozesh, 2013, Drug metabolism letters.

Identification of selective mechanism-based inactivators of cytochromes P-450 2B4 and 2B5, and determination of the molecular basis for differential susceptibility.

M. Foroozesh, J. Halpert, G. Szklarz, 1999, The Journal of pharmacology and experimental therapeutics.

Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.

M. Foroozesh, F. Guengerich, Z. Guo, 1997, Chemical research in toxicology.

Potent mechanism-based inactivation of cytochrome P450 2B4 by 9-ethynylphenanthrene: implications for allosteric modulation of cytochrome P450 catalysis.

Jiawang Liu, M. Foroozesh, J. Halpert, 2013, Biochemistry.

Inhibition of cytochrome p450 enzymes by quinones and anthraquinones.

J. Sridhar, Jiawang Liu, M. Foroozesh, 2012, Chemical research in toxicology.

Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study.

Hiroshi Yamazaki, F Peter Guengerich, Tsutomu Shimada, 2009, Chemical research in toxicology.

Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.

H. Yamazaki, M. Foroozesh, T. Shimada, 1998, Chemical research in toxicology.

Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and Their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6.

H. Yamazaki, M. Foroozesh, T. Shimada, 2016, Chemical research in toxicology.

Structure − Function Studies of Naphthalene , Phenanthrene , Biphenyl , and Their Derivatives in Interaction with and Oxidation by Cytochromes P 450 2 A 13 and 2 A 6

H. Yamazaki, M. Foroozesh, T. Shimada, 2016 .

Methoxyflavone Inhibitors of Cytochrome P450

M. Foroozesh, N. Zhu, C. Stevens, 2008 .

Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13

H. Yamazaki, Jiawang Liu, M. Foroozesh, 2016, Xenobiotica; the fate of foreign compounds in biological systems.

Student Grade Evaluation, Survey Feedback, and Lessons Learned during the COVID-19 Pandemic: A Comparative Study of Virtual vs. In-Person Offering of a Freshman-Level General Chemistry II Course in Summer at Xavier University of Louisiana

M. Foroozesh, T. Coston, Asem Abdulahad, 2022, Education Sciences.

Building integrated pathways to independence for diverse biomedical researchers: Project Pathways, the BUILD program at Xavier University of Louisiana

M. Foroozesh, T. Coston, K. Morgan, 2017, BMC Proceedings.

Baseline Characteristics of the 2015-2019 First Year Student Cohorts of the NIH Building Infrastructure Leading to Diversity (BUILD) Program.

Christina A. Christie, Laura E Ott, C. Pfund, 2020, Ethnicity & disease.

QSAR models of cytochrome P450 enzyme 1A2 inhibitors using CoMFA, CoMSIA and HQSAR

J. Sridhar, M. Foroozesh, J Sridhar, 2011, SAR and QSAR in environmental research.

Naphthoflavone propargyl ether inhibitors of cytochrome P450

M. Foroozesh, Cheryl L. Klein Stevens, A. Chaudhary, 2006 .

Polyacetylenes from Chrysoma pauciflosculosa: Effects on florida sandhill species

G. B. Williamson, M. Foroozesh, F. Fronczek, 1992 .

Ethynyl and Propynylpyrene Inhibitors of Cytochrome P450

Jiawang Liu, M. Foroozesh, E. Stevens, 2010, Journal of chemical crystallography.

Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.

H. Yamazaki, M. Foroozesh, T. Shimada, 2013, Chemical research in toxicology.

Ethynylflavones, Highly Potent, and Selective Inhibitors of Cytochrome P450 1A1

Ming Zhao, J. Sridhar, Jiawang Liu, 2014, Chemical research in toxicology.