M. D. de Jager

发表

Prediction of whole-body metabolic clearance of drugs through the combined use of slices from rat liver, lung, kidney, small intestine and colon

R. de Kanter, M. Monshouwer, A. L. Draaisma, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

The Consequence of Drug–Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2016, Drug Metabolism and Disposition.

Caffeine-based gold(I) N-heterocyclic carbenes as possible anticancer agents: synthesis and biological properties.

Benoît Bertrand, Ewen Bodio, A. Casini, 2014, Inorganic chemistry.

Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices

P. Olinga, R. de Kanter, A. L. Draaisma, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Reduced Ischemia-Reoxygenation Injury in Rat Intestine After Luminal Preservation With a Tailored Solution

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2010, Transplantation.

The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo.

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2017, Toxicology in vitro : an international journal published in association with BIBRA.

Organ slices as an in vitro test system for drug metabolism in human liver, lung and kidney.

P. Olinga, R. de Kanter, M. D. de Jager, 1999, Toxicology in vitro : an international journal published in association with BIBRA.

Adipose Stromal Cell-Secretome Counteracts Profibrotic Signals From IPF Lung Matrices

M. D. de Jager, M. Harmsen, E. White, 2021, Frontiers in Pharmacology.

The applicability of rat and human liver slices to the study of mechanisms of hepatic drug uptake.

P. Olinga, M. D. de Jager, G. Groothuis, 2001, Journal of pharmacological and toxicological methods.

Induction of Phase I and II Drug Metabolism in Rat Small Intestine and Colon in Vitro

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2007, Drug Metabolism and Disposition.

A new technique for preparing precision-cut slices from small intestine and colon for drug biotransformation studies.

R. de Kanter, A. L. Draaisma, M. D. de Jager, 2005, Journal of pharmacological and toxicological methods.

CHARACTERIZATION OF RAT SMALL INTESTINAL AND COLON PRECISION-CUT SLICES AS AN IN VITRO SYSTEM FOR DRUG METABOLISM AND INDUCTION STUDIES

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2005, Drug Metabolism and Disposition.

Innovative Methods to Study Human Intestinal Drug Metabolism in Vitro: Precision-Cut Slices Compared with Ussing Chamber Preparations

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2006, Drug Metabolism and Disposition.

Nanoparticle Formulation of a Poorly Soluble Cannabinoid Receptor 1 Antagonist Improves Absorption by Rat and Human Intestine

W. Hinrichs, H. Frijlink, M. D. de Jager, 2013, Drug Metabolism and Disposition.

Rat liver slices as a tool to study LPS-induced inflammatory response in the liver.

P. Olinga, M. D. de Jager, G. Groothuis, 2001, Journal of hepatology.

A rapid and simple method for cryopreservation of human liver slices.

P. Olinga, R. de Kanter, M. D. de Jager, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Effect of cold and warm ischaemia on drug metabolism in isolated hepatocytes and slices from human and monkey liver.

P. Olinga, M. D. de Jager, D. Meijer, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

EMPIRICAL VALIDATION OF A RAT IN VITRO ORGAN SLICE MODEL AS A TOOL FOR IN VIVO CLEARANCE PREDICTION

R. de Kanter, M. D. de Jager, I. A. D. de Graaf, 2006, Drug Metabolism and Disposition.

Regional Differences in Human Intestinal Drug Metabolism

P. Olinga, M. D. de Jager, R. Iswandana, 2018, Drug Metabolism and Disposition.

Human and rat precision‐cut intestinal slices as ex vivo models to study bile acid uptake by the apical sodium‐dependent bile acid transporter

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

P‐gp activity and inhibition in the different regions of human intestine ex vivo

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2017, Biopharmaceutics & drug disposition.

CHARACTERIZATION OF RAT SMALL INTESTINAL AND COLON PRECISION-CUT SLICES AS AN IN VITRO SYSTEM FOR DRUG METABOLISM AND INDUCTION STUDIES

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2005, Drug Metabolism and Disposition.

Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo.

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2015, Toxicology in vitro : an international journal published in association with BIBRA.