I. Fidler

I. Fidler, A. Schroit, S. Ratner, 1986, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Design of liposomes to improve delivery of macrophage-augmenting agents to alveolar macrophages.

I. Fidler, G. Poste, A. Raz, 1980, Cancer research.

Critical determinants of neoplastic angiogenesis.

L. Ellis, R. Kumar, I. Fidler, 2000, Cancer journal.

Characterization of human colon carcinoma variant cells selected for sialyl Lex carbohydrate antigen: liver colonization and adhesion to vascular endothelial cells.

T. Irimura, I. Fidler, C. Smith, 1995, Experimental cell research.

Targeting receptor tyrosine kinase on lymphatic endothelial cells for the therapy of colon cancer lymph node metastasis.

I. Fidler, J. Gershenwald, R. Langley, 2006, Neoplasia.

Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into different sites in nude mice.

I. Fidler, J. Jessup, K. Cleary, 1986, Cancer research.

Stimulation of the RES and Control of Cancer Metastasis

I. Fidler, V. Pollack, 1983 .

Cancer Growth, Progression and Metastasis

I. Fidler, J. Killion, 2005 .

Characterization of the invasive and metastatic phenotype in human renal cell carcinoma

I. Fidler, S. Naito, J. Price, 1991, Clinical & Experimental Metastasis.

Growth in an organ microenvironment as a selective process in metastasis

I. Fidler, S. Naito, J. Price, 2005, Clinical & Experimental Metastasis.

In situ activation of tumoricidal properties in rat alveolar macrophages and rejection of experimental lung metastases by intravenous injections of Nocardia rubra cell wall skeleton

I. Fidler, S. Sone, 1982, Cancer Immunology, Immunotherapy.

Systemic activation of macrophages by liposome-entrapped muramyl tripeptide in mice pretreated with the chemotherapeutic agent adriamycin

I. Fidler, G. Hisano, 1982, Cancer Immunology, Immunotherapy.

Direct activation of tumoricidal properties in rat alveolar macrophages by Nocardia rubra cell wall skeleton

I. Fidler, S. Sone, V. Pollack, 2004, Cancer Immunology, Immunotherapy.

The Biology of Melanoma Brain Metastasis

I. Fidler, G. Schackert, R. Radinsky, 2004, Cancer and Metastasis Reviews.

Macrophage-mediated destruction of malignant tumor cells and new strategies for the therapy of metastatic disease

I. Fidler, G. Poste, 1982, Springer Seminars in Immunopathology.

Therapy of cancer metastasis by tumoricidal activation of tissue macrophages using liposome-encapsulated immunomodulators.

I. Fidler, J. Killion, 1998, Pharmacology & therapeutics.

Isolation and characterization of metastatic variants from human transitional cell carcinoma passaged by orthotopic implantation in athymic nude mice.

C. Bucana, C. Dinney, I. Fidler, 1995, The Journal of urology.

Regulation of Gelatinase Production in Metastatic Renal Cell Carcinoma by Organ‐specific Fibroblasts

C. Bucana, T. Tsuruo, I. Fidler, 1994, Japanese journal of cancer research : Gann.

Therapy of disseminated melanoma by liposome-activated macrophages

I. Fidler, 1992, World journal of surgery.

Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice.

C. Bucana, I. Fidler, M. Nakajima, 1992, Differentiation; research in biological diversity.

Renal Cell Carcinoma: Experimental Metastases

I. Fidler, J. Killion, 1991 .

Liposomal delivery of biological response modifiers to macrophages

I. Fidler, C. Pak, Isaiah J. Fidler, 1991, Biotherapy.

Predominance of the metastatic phenotype in somatic cell hybrids of the K-1735 murine melanoma.

I. Fidler, S. Tucker, S. Pathak, 1991, Cancer research.

Specific chromosomal defects associated with metastatic potential in K-1735 melanoma clones. Involvement of chromosomes 4 and 14.

I. Fidler, S. Pathak, A. Staroselsky, 1991, Cancer genetics and cytogenetics.

Genetic control of cancer metastasis.

I. Fidler, R. Radinsky, 1990, Journal of the National Cancer Institute.

Regional growth of different human melanomas as metastases in the brain of nude mice.

C. Bucana, I. Fidler, G. Schackert, 1990, The American journal of pathology.

Metastatic potential of human colorectal carcinomas implanted into nude mice: prediction of clinical outcome in patients operated upon for cure.

I. Fidler, E. Atkinson, J. Jessup, 1989, Cancer research.

Metastatic potential of cloned murine melanoma cells transfected with activated c-Ha-ras.

I. Fidler, G. Schackert, H. Ananthaswamy, 1989, Cancer research.

Circumvention of Neoplastic Heterogeneity by Systemically Activated Macrophages

I. Fidler, J. Jessup, A. Mazumder, 1986 .

The Use of Activated Macrophages for the Destruction of Heterogeneous Metastasis

I. Fidler, A. Schroit, 1986 .

The Recognition and Destruction of Metastatic Cells by Tumoricidal Macrophages

I. Fidler, 1986 .

Activation of tumoricidal properties in peripheral blood monocytes of patients with colorectal carcinoma.

I. Fidler, J. Jessup, A. Mazumder, 1986, Cancer research.

Development of BiologicalDiversityand Susceptibility to Chemotherapy in MurineCancerMÃ©tastases

I. Fidler, J. Talmadge, J. Madsen, 1984 .

Role of Macrophages in Host Resistance Against Tumors

I. Fidler, W. Fogler, 1983 .

Comparative studies on the quantitative analysis of experimental metastatic capacity.

I. Fidler, J. Talmadge, I. Hart, 1983, Cancer research.

Systemic Activation of Macrophages and Treatment of Cancer Metastases by Liposomes containing Hydrophilic or Lipophilic Muramyl Dipeptide

I. Fidler, A. Schroit, W. Fogler, 1983 .

Eradication of metastases by tumoricidal macrophages: therapeutic implications

I. Fidler, 1982 .

Stimulation of Host Response Against Metastatic Tumors by Liposome-Encapsulated Immunomodulators

C. Bucana, I. Fidler, G. Poste, 1982 .

The biologic diversity of cancer metastases.

I. Fidler, G. Poste, 1982, Hospital practice.

Macrophages and cancer metastasis.

I. Fidler, G. Poste, 1982, Advances in experimental medicine and biology.

In vitro activation of tumoricidal properties in rat alveolar macrophages by synthetic muramyl dipeptide encapsulated in liposomes.

I. Fidler, S. Sone, 1981, Cellular immunology.

Differences in drug sensitivity among tumor cells from parental tumors, selected variants, and spontaneous metastases.

T. Tsuruo, I. Fidler, 1981, Cancer research.

Distribution of membrane anionic sites on B16 melanoma variants with differing lung colonising potential

C. Bucana, I. Fidler, A. Raz, 1980, Nature.

In situ activation of murine macrophages by liposomes containing lymphokines.

I. Fidler, A. Raz, W. Fogler, 1980, Cellular immunology.

Cancer Invasion and Metastasis

I. Fidler, I. Hart, 1980, The Quarterly Review of Biology.

Characterization in vivo and in vitro of tumor cells selected for resistance to syngeneic lymphocyte-mediated cytotoxicity.

I. Fidler, D. Gersten, M. B. Budmen, 1976, Cancer research.

Activation of tumoricidal properties in mouse macrophages by lymphokines encapsulated in liposomes.

I. Fidler, G. Poste, W. Fogler, 1979, Cancer research.

The cellular heterogeneity of malignant neoplasms: implications for adjuvant chemotherapy.

I. Fidler, G. Poste, 1985, Seminars in oncology.

Recent concepts of cancer metastasis and their implications for therapy.

I. Fidler, 1984, Cancer treatment reports.

Blockade of epidermal growth factor receptor signaling leads to inhibition of renal cell carcinoma growth in the bone of nude mice.

I. Fidler, K. Weber, S. J. Kim, 2003, Cancer research.

Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinoma.

L. Ellis, C. Bucana, I. Fidler, 1996, The American journal of pathology.

Tumor Cell and Endothelial Cell Therapy of Oral Cancer by Dual Tyrosine Kinase Receptor Blockade

C. Bucana, I. Fidler, J. Myers, 2004, Cancer Research.

Plasma protein profiling for diagnosis of pancreatic cancer reveals the presence of host response proteins.

Kevin R Coombes, John M Koomen, K. Coombes, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Systemic activation of tumoricidal properties in mouse macrophages and inhibition of melanoma metastases by the oral administration of MTP-PE, a lipophilic muramyl dipeptide.

I. Fidler, W. Fogler, G. Schumann, 1987, Journal of immunology.

Tumoricidal activity of human monocytes activated in vitro by free and liposome-encapsulated human lymphokines.

I. Fidler, A. Schroit, W. Fogler, 1983, The Journal of clinical investigation.

Macrophage content of metastatic and nonmetastatic rodent neoplasms.

I. Fidler, J. Talmadge, M. Key, 1981, Journal of immunology.

Macrophages and metastasis--a biological approach to cancer therapy.

I. Fidler, 1985, Cancer research.

Destruction of tumor cells by monokines released from activated human blood monocytes: evidence for parallel and additive effects of IL-1 and TNF

J. Y. Tsao, Y. Ichinose, I. Fidler, 1988, Cancer Immunology, Immunotherapy.

Effects of tertiary amine local anesthetics on the blood-borne implantation and cell surface properties of metastatic mouse melanoma cells.

G. Nicolson, I. Fidler, G. Poste, 1986, Journal of the National Cancer Institute.

Critical determinants of melanoma metastasis.

I. Fidler, 1996, The journal of investigative dermatology. Symposium proceedings.

Mechanisms of Cancer Invasion and Metastasis

I. Fidler, 1975 .

Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53.

C. Bucana, I. Fidler, M. Bar‐eli, 1994, Oncogene.

Epidermal hyperplasia overlying human melanoma correlates with tumour depth and angiogenesis

C. Bucana, I. Fidler, J. Gershenwald, 2003, Melanoma research.

Unique histological changes in lung metastases of osteosarcoma patients following therapy with liposomal muramyl tripeptide (CGP 19835A lipid)

C. Bucana, E. Kleinerman, N. Jaffe, 1992, Cancer Immunology, Immunotherapy.

Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis

T. McDonnell, J. Reed, John Calvin Reed, 1996, Cancer Immunology, Immunotherapy.

Thein vitro invasiveness and interactions with laminin of K-1735 melanoma cells. Evidence for different laminin-binding affinities in high and low metastatic variants

I. Fidler, D. Noonan, A. Albini, 1989, Clinical & Experimental Metastasis.

Enhancement of murine tumor cell sensitivity to adriamycin by presentation of the drug in phosphatidylcholine-phosphatidylserine liposomes.

C. Bucana, I. Fidler, L. Zwelling, 1990, Cancer research.

Use of retroviral vectors encoding murine inducible nitric oxide synthase gene to suppress tumorigenicity and cancer metastasis of murine melanoma.

I. Fidler, K. Xie, J. Yoneda, 1997, Cancer biotherapy & radiopharmaceuticals.

Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophages.

I. Fidler, K. Xie, X. Qi, 1993, Journal of immunology.

Expression of lnterleukin-8 Correlates with Vascularity in Human Gastric Carcinomas

I. Fidler, K. Haruma, H. Yokozaki, 2007 .

Inhibition of Growth and Metastasis of Orthotopic Human Prostate Cancer in Athymic Mice by Combination Therapy with Pegylated Interferon-- 2 b and Docetaxel

C. Bucana, C. Dinney, I. Fidler, 2002 .

Blockade of the epidermal growth factor receptor signaling inhibits angiogenesis leading to regression of human renal cell carcinoma growing orthotopically in nude mice.

C. Dinney, I. Fidler, C. Baker, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Inhibition of growth and metastasis of orthotopic human prostate cancer in athymic mice by combination therapy with pegylated interferon-alpha-2b and docetaxel.

C. Bucana, C. Dinney, I. Fidler, 2002, Cancer research.

Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha.

L. Ellis, C. Bucana, I. Fidler, 2001, Neoplasia.

Nuclear Factor- k B Activity Correlates with Growth, Angiogenesis, and Metastasis of Human Melanoma Cells in Nude Mice 1

C. Bucana, I. Fidler, Suyun Huang, 2000 .

Cell density-dependent regulation of basic fibroblast growth factor expression in human renal cell carcinoma cells.

C. Bucana, I. Fidler, R. Singh, 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells.

C. Bucana, Mike Wilson, I. Fidler, 1994, The American journal of pathology.

Suppression of tumorigenicity and metastasis in murine UV-2237 fibrosarcoma cells by infection with a retroviral vector harboring the interferon-beta gene

C. Bucana, I. Fidler, Rakesh Kumar, 1998, Cancer Immunology, Immunotherapy.

Quantitative fluorescent microassay for identification of antiproliferative compounds.

J. Y. Tsao, C. Bucana, I. Fidler, 1986, Journal of the National Cancer Institute.

Formation of solid tumors by a single multinucleated cancer cell

I. Fidler, Z. Weihua, D. Fan, 2011, Cancer.

Tumor cell and host properties affecting the implantation and survival of blood-borne metastatic variants of B16 melanoma.

G. Nicolson, I. Fidler, 1978, Israel journal of medical sciences.

Activation or suppression of the tumoricidal properties of monocytes from cancer patients following treatment with human recombinant gamma-interferon.

E. Kleinerman, I. Fidler, R. Kurzrock, 1986, Cancer research.

Cell density-dependent regulation of mdr-1 gene expression in murine colon cancer cells.

C. Bucana, Y. Wang, I. Fidler, 1996, International journal of oncology.

Evidence for metastatic heterogeneity of human renal cell carcinoma.

I. Fidler, A. V. von Eschenbach, S. Naito, 1988, Anticancer research.

Use of young nude mice for selection of subpopulations of cells with increased metastatic potential from nonsyngeneic neoplasms.

I. Fidler, V. Pollack, 1982, Journal of the National Cancer Institute.

In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice

I. Fidler, S. Naito, S. Walker, 1989, Clinical & Experimental Metastasis.

Experimental nude mouse model of human colorectal cancer liver metastases.

I. Fidler, J. Jessup, R. Giavazzi, 1986, Journal of the National Cancer Institute.

Malignant: Role of natural killer cells in the destruction of circulating tumor emboli

I. Fidler, H. Bingham, N. Hanna, 1981 .

In vivo isolation of a metastatic tumor cell variant involving selective and nonadaptive processes.

I. Fidler, A. Raz, N. Hanna, 1981, Journal of the National Cancer Institute.

The Ernst W. Bertner Memorial Award lecture: the evolution of biological heterogeneity in metastatic neoplasms.

I. Fidler, 1983, Symposium on Fundamental Cancer Research.

Growth and metastatic behavior of human tumor cells implanted into nude and beige nude mice

I. Fidler, S. Naito, R. Giavazzi, 1987, Clinical & Experimental Metastasis.

Enhanced metastatic potential of tumor cells harvested from spontaneous metastases of heterogeneous murine tumors.

I. Fidler, J. Talmadge, 1982, Journal of the National Cancer Institute.

Different growth pattern and biologic behavior of human renal cell carcinoma implanted into different organs of nude mice.

I. Fidler, A. V. von Eschenbach, S. Naito, 1987, Journal of the National Cancer Institute.

Relationship Between Metastatic Potential and Resistance to Natural Killer Cellmediated Cytotoxicity in Three Murine Tumor Systems

I. Fidler, N. Hanna, 1981 .

Development of an animal model to study the biology of recurrent colorectal cancer originating from mesenteric lymph system metastases

I. Fidler, H. Schackert, 1989, International journal of cancer.

Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products

I. Fidler, X. Qi, Z. Dong, 1993, The Journal of experimental medicine.

Regulation of carcinoembryonic antigen expression in human colon carcinoma cells by the organ microenvironment.

C. Bucana, I. Fidler, R. Radinsky, 1996, The American journal of pathology.

Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase gene.

I. Fidler, K. Xie, Z. Dong, 1997, Journal of the National Cancer Institute.

Human recombinant interferons‐beta and ‐gamma decrease gelatinase production and invasion by human KG‐2 renal‐carcinoma cells

T. Tsuruo, I. Fidler, A. V. von Eschenbach, 1994, International journal of cancer.

Interferon-β prevents the upregulation of interleukin-8 expression in human melanoma cells

I. Fidler, Rakesh K. Singh, M. Gutman, 1996 .

Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells.

I. Fidler, C. Dinarello, L. Lachman, 1986, Journal of immunology.

Prevention of intestinal toxic effects and intensification of irinotecan's therapeutic efficacy against murine colon cancer liver metastases by oral administration of the lipopeptide JBT 3002.

R. Kumar, I. Fidler, H. Kuniyasu, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide.

I. Fidler, S. Sone, W. Fogler, 1981, Proceedings of the National Academy of Sciences of the United States of America.

In vivo modulation of macrophage tumoricidal activity by oral administration of the liposome-encapsulated macrophage activator CGP 19835A.

C. Bucana, I. Fidler, A. V. von Eschenbach, 1994, Cancer research.

Sequential therapy with chemotherapeutic drugs and liposome-encapsulated muramyl tripeptide: determination of potential interactions between these agents.

I. Fidler, M. Wilson, J. Killion, 1992, Oncology research.

Regulation of tumor cell growth at organ-specific metastases.

I. Fidler, R. Radinsky, 1992, In vivo.

Expression of theJE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells

C. Bucana, I. Fidler, M. Bar‐eli, 1994, Cancer Immunology, Immunotherapy.

The in situ activation of cytotoxic properties in murine Kupffer cells by the systemic administration of whole Mycobacterium bovis organisms or muramyl tripeptide

I. Fidler, Zuliang Xu, 1984, Cancer Immunology, Immunotherapy.

Tumor cytotoxicity of rat alveolar macrophages activated in vitro by endotoxin.

I. Fidler, S. Sone, 1980, Journal of the Reticuloendothelial Society.

Rat alveolar macrophages are susceptible to activation by free and liposome-encapsulated lymphokines.

I. Fidler, G. Poste, S. Sone, 1980, Journal of immunology.

Recognition and destruction of target cells by tumoricidal macrophages.

I. Fidler, 1978, Israel journal of medical sciences.

The effects of experimental conditions on the expression of in vitro-mediated tumor cytotoxicity mediated by murine macrophages

I. Fidler, A. Raz, W. Fogler, 2004, Cancer Immunology, Immunotherapy.

Activation in vitro of mouse macrophages by syngeneic, allogeneic, or xenogeneic lymphocyte supernatants.

I. Fidler, 1975, Journal of the National Cancer Institute.

Activation of rat alveolar macrophages to the tumoricidal state in the presence of progressively growing pulmonary metastases.

I. Fidler, S. Sone, 1981, Cancer research.

Therapy of human pancreatic carcinoma implants by irinotecan and the oral immunomodulator JBT 3002 is associated with enhanced expression of inducible nitric oxide synthase in tumor-infiltrating macrophages.

I. Fidler, D. McConkey, D. Davis, 2000, Cancer research.

Advances in Brief Therapy of Human Pancreatic Carcinoma Implants by Irinotecan and the Oral Immunomodulator JBT 3002 Is Associated with Enhanced Expression of Inducible Nitric Oxide Synthase in Tumor-infiltrating Macrophages 1

I. Fidler, D. McConkey, D. Davis, 2000 .

Systemic macrophage activation with liposome-entrapped immunomodulators for therapy of cancer metastasis.

I. Fidler, 1992, Research in immunology.

Unique patterns of brain metastasis produced by different human carcinomas in athymic nude mice

C. Bucana, I. Fidler, G. Schackert, 1989, International journal of cancer.

Synergism between human recombinant gamma-interferon and muramyl dipeptide encapsulated in liposomes for activation of antitumor properties in human blood monocytes.

I. Fidler, S. Sone, G. Lopez-Berestein, 1985, Cancer research.

Epidermoid Carcinoma Cells

C. Bucana, I. Fidler, B. Xie, 2007 .

In situ mRNA hybridization technique for analysis of metastasis-related genes in human colon carcinoma cells.

L. Ellis, C. Bucana, I. Fidler, 1995, The American journal of pathology.

Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis.

Kazuhiro Yoshida, I. Fidler, T. Sasahira, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Differential regulation of type IV collagenases and metalloelastase in murine macrophages by the synthetic bacterial lipopeptide JBT 3002.

R. Kumar, I. Fidler, K. Xie, 2000, International journal of immunopharmacology.

EXPOSURE OF MICE TO UV‐B RADIATION SUPPRESSES DELAYED HYPERSENSITIVITY TO Candida albicans

I. Fidler, M. Kripke, Y. Denkins, 1989, Photochemistry and photobiology.

Colony-Stimulating Factor in Human Colon Expression of Granulocyte-Macrophage Macrophage Cytotoxicity by Engineered Enhancement of Contact-Dependent Induction of Chemokine Secretion and

C. Bucana, I. Fidler, S. Yano, 2013 .

Induction of Chemokine Secretion and Enhancement of Contact-Dependent Macrophage Cytotoxicity by Engineered Expression of Granulocyte-Macrophage Colony-Stimulating Factor in Human Colon Cancer Cells1

C. Bucana, I. Fidler, S. Yano, 2000, The Journal of Immunology.

Evidence for the causal role of endogenous interferon-alpha/beta in the regulation of angiogenesis, tumorigenicity, and metastasis of cutaneous neoplasms.

C. Bucana, I. Fidler, C. Donawho, 2002, Clinical & experimental metastasis.

Inhibition by tertiary amine local anesthetics of phagocytosis in cultured mouse peritoneal macrophages.

I. Fidler, W. Fogler, D. Gersten, 1978, Biochemical pharmacology.

Quantitative analysis of macrophage phagocytosis by uptake of particulate 192iridium.

I. Fidler, W. Fogler, D. Gersten, 1977, Journal of immunological methods.

The influence of host health and environment on natural cytotoxicity of mouse macrophages

I. Fidler, T. Davis, A. Raz, 1981, Cancer Immunology, Immunotherapy.

Intracellular Activation of Human and Rodent Macrophages by Human Lymphokines Encapsulated in Liposomes

I. Fidler, W. Fogler, E. Kleinerman, 1985, Journal of leukocyte biology.

Reversal of multidrug resistance in murine fibrosarcoma cells by thioxanthene flupentixol

I. Fidler, G. Poste, C. Seid, 1994, Investigational New Drugs.

Progress in Anti-Cancer Chemotherapy

G. Hortobagyi, I. Fidler, D. Khayat, 2000, Progress in Anti-Cancer Chemotherapy.

Inhibition of PDGFR phosphorylation and Src and Akt activity by GN963 leads to therapy of human pancreatic cancer growing orthotopically in nude mice.

I. Fidler, J. Trevino, G. Gallick, 2006, International journal of oncology.

Treatment of nude mice with 4‐amidinoindan‐1‐one2′‐amidinohydrazone, a new S‐adenosylmethionine decarboxylase inhibitor, delays growth and inhibits metastasis of human melanoma cells

I. Fidler, M. Wilson, D. Fan, 1995, Melanoma research.

Progressive upregulation of metastasis-related genes in human colon cancer cells implanted into the cecum of nude mice.

L. Ellis, C. Bucana, I. Fidler, 1996, Oncology research.

Activation of inducible nitric oxide synthase gene in murine macrophages requires protein phosphatases 1 and 2A activities

I. Fidler, K. Xie, Xiulan Yang, 1995, Journal of leukocyte biology.

Comparative efficacy of liposomes containing synthetic bacterial cell wall analogues for tumoricidal activation of monocytes and macrophages

I. Fidler, Y. Denkins, C. Pak, 1991, Cancer Immunology, Immunotherapy.

The development of biological diversity and metastatic potential in malignant neoplasms.

I. Fidler, I. Hart, 1982, Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine.

GM‐CSF‐transduced B16 melanoma cells are highly susceptible to lysis by normal murine macrophages and poorly tumorigenic in immune‐compromised mice

R. Kumar, I. Fidler, Z. Dong, 1999, Journal of leukocyte biology.

Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells.

C. Bucana, I. Fidler, M. Bar‐eli, 1994, Cancer immunology, immunotherapy : CII.

Immunotherapy of murine renal adenocarcinoma by systemic administration of liposomes containing the synthetic macrophage activator CGP 31362 or CGP 19835A in combination with interleukin 2 or gamma-interferon.

C. Dinney, I. Fidler, A. V. von Eschenbach, 1992, Cancer research.

Potent in situ activation of murine lung macrophages and therapy of melanoma metastases by systemic administration of liposomes containing muramyltripeptide phosphatidylethanolamine and interferon gamma.

Y. Ichinose, I. Fidler, D. Fan, 1989, Invasion & metastasis.

Synergistic activation by recombinant mouse interferon-gamma and muramyl dipeptide of tumoricidal properties in mouse macrophages.

I. Fidler, I. Saiki, 1985, Journal of immunology.

Angiogenesis and cancer metastasis.

I. Fidler, 2000, Cancer journal.

Different patterns of macrophage infiltration into allogeneic-murine and xenogeneic-human neoplasms growing in nude mice.

C. Bucana, I. Fidler, R. Sanchez, 1992, The American journal of pathology.

Plasma membrane-associated tumor necrosis factor. A non-integral membrane protein possibly bound to its own receptor.

Y. Ichinose, I. Fidler, L. Lachman, 1988, Journal of immunology.

Heterogeneous response of human colon cancer cells to the cytostatic and cytotoxic effects of recombinant human cytokines: interferon-alpha, interferon-gamma, tumor necrosis factor, and interleukin-1.

I. Fidler, K. Morikawa, 1989, Journal of biological response modifiers.

The recognition of red blood cells by macrophages: role of phosphatidylserine and possible implications of membrane phospholipid asymmetry

I. Fidler, A. Schroit, Y. Tanaka, 1984, Biology of the cell.

Organ-site dependence for the production of urokinase-type plasminogen activator and metastasis by human renal cell carcinoma cells.

C. Bucana, C. Dinney, I. Fidler, 1997, The American journal of pathology.

Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells.

C. Bucana, I. Fidler, M. Nakajima, 1990, Journal of the National Cancer Institute.

Antigenicity of UV radiation-induced murine tumors correlates positively with the level of adenosine deaminase activity

I. Fidler, S. L. Aukerman, 1987, Cancer Immunology, Immunotherapy.

Nuclear factor-kappaB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice.

C. Bucana, I. Fidler, S. Huang, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

High-Risk Breast Cancer

I. Fidler, 1991, Springer Berlin Heidelberg.

Neutralization of endogenous interferon-beta increases the efficiency of adenoviral vector-mediated gene transduction.

I. Fidler, Z. Dong, X. Yang, 1997, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Expression of inflammatory cytokines by murine macrophages activated with a new synthetic lipopeptide JT3002.

R. Kumar, I. Fidler, Z. Dong, 1997, Cancer biotherapy & radiopharmaceuticals.

Arrest and retention of multilamellar liposomes in the brain of normal mice or mice bearing experimental brain metastases.

I. Fidler, G. Schackert, R. Nayar, 1989, Selective cancer therapeutics.

Lack of comparability between binding of monoclonal antibodies to melanoma cells in vitro and localization in vivo.

J. Murray, I. Fidler, C. Balch, 1989, Journal of the National Cancer Institute.

Glucan: attempts to demonstrate therapeutic activity against five syngeneic tumors in guinea pigs and mice.

M. Hanna, B. Zbar, I. Fidler, 1978, Journal of the National Cancer Institute.

Correlation between the in vitro interaction of tumor cells with an organ environment and metastatic behavior in vivo.

I. Fidler, S. Naito, R. Giavazzi, 1987, Invasion & metastasis.

Metastatic behavior of a murine reticulum cell sarcoma exhibiting organ-specific growth.

I. Fidler, J. Talmadge, I. Hart, 1981, Cancer research.

Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells.

I. Fidler, K. Xie, X. Qi, 1994, Cancer research.

Metastatic Potential Cell Surface Properties of B 16 Melanoma Variants with Differing Updated

C. Bucana, I. Fidler, A. Raz, 2006 .

The effect of human recombinant macrophage colony-stimulating factor (CSF-1) on the murine mononuclear phagocyte system in vivo.

D. Hume, I. Fidler, P. Pavli, 1988, Journal of immunology.

Ultraviolet-B-irradiated mouse epidermis releases mediators that stimulate melanoma cells.

I. Fidler, M. Kripke, C. Wang, 1990, Photodermatology, photoimmunology & photomedicine.

Cell surface receptors for lymphokines. I. The possible role of glycolipids as receptors for macrophage migration inhibitory factor (MIF) and macrophage activation factor (MAF).

I. Fidler, G. Poste, R. Kirsh, 1979, Cellular immunology.

Activation of cytokine production, tumoricidal properties, and tyrosine phosphorylation of MAPKs in human monocytes by a new synthetic lipopeptide, JBT3002

I. Fidler, Rakesh Kumar, Xiulan Yang, 1998, Journal of leukocyte biology.

Activation of tumoricidal properties in monocytes from cancer patients following intravenous administration of liposomes containing muramyl tripeptide phosphatidylethanolamine.

E. Kleinerman, J. Murray, I. Fidler, 1989, Cancer research.

Molecular mechanisms for activated macrophage recognition of tumor cells.

I. Fidler, C. Pak, 1991, Seminars in cancer biology.

Activated macrophages distinguish undifferentiated-tumorigenic from differentiated-nontumorigenic murine erythroleukemia cells.

I. Fidler, C. Pak, 1989, Differentiation; research in biological diversity.

Induction of ductal and stromal hyperplasia by basic fibroblast growth factor produced by human pancreatic carcinoma.

I. Fidler, J. Abbruzzese, K. Cleary, 2001, International journal of oncology.

Workgroup 2: Human xenograft models of prostate cancer

I. Fidler, D. Agus, M. Kinch, 1998, The Prostate.

Potentiation of direct antitumor cytotoxicity and production of tumor cytolytic factors in human blood monocytes by human recombinant interferon-gamma and muramyl dipeptide derivatives

I. Fidler, S. Sone, G. Lopez-Berestein, 1986, Cancer Immunology, Immunotherapy.

Human lymphokine preparations which generate tumoricidal properties of human monocytes in vitro may be distinct from gamma interferon

I. Fidler, R. Wiltrout, E. Kleinerman, 1985, Cancer Immunology, Immunotherapy.

Efficient activation of human blood monocytes to a tumoricidal state by liposomes containing human recombinant gamma interferon

I. Fidler, W. Koff, J. Gutterman, 1985, Cancer Immunology, Immunotherapy.

Mechanisms of combined effects of gamma-interferon and 5-fluorouracil on human colon cancers implanted into nude mice.

B. Levin, I. Fidler, J. Gutterman, 1989, Cancer research.

Augmentation of antiproliferative activity of interferon alfa against human bladder tumor cell lines by encapsulation of interferon alfa within liposomes.

C. Bucana, I. Fidler, J. Price, 1989, Journal of the National Cancer Institute.

Cytokine-induced apoptosis in transformed murine fibroblasts involves synthesis of endogenous nitric-oxide.

I. Fidler, K. Xie, Z. Dong, 1993, International journal of oncology.

Involvement of macrophages in the eradication of established metastases following intravenous injection of liposomes containing macrophage activators.

I. Fidler, G. Poste, P. Bugelski, 1982, Cancer research.

Eradication of primary murine fibrosarcomas and induction of systemic immunity by adenovirus-mediated interferon beta gene therapy.

I. Fidler, Z. Dong, W. Lu, 1999, Cancer research.

Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2

I. Fidler, D. McConkey, Suyun Huang, 1997, Oncogene.

Different deficiencies in the prevention of tumorigenic-low-metastatic murine K-1735b melanoma cells from producing metastases.

I. Fidler, J. Price, S. L. Aukerman, 1986, Journal of the National Cancer Institute.

Role of Natural Killer Cells in the Destruction of Circulating Tumor Emboli

I. Fidler, N. Hanna, 1980 .

Mechanism of tumor cell resistance to lysis by syngeneic lymphocytes.

C. Bucana, I. Fidler, 1977, Cancer research.

Lack of correlation between the progressive growth of spontaneous metastases and their content of infiltrating macrophages.

I. Fidler, J. Talmadge, M. Key, 1982, Journal of the Reticuloendothelial Society.

Properties of metastatic and nonmetastatic cloned subpopulations of an ultraviolet-light-induced murine fibrosarcoma of recent origin.

I. Fidler, M. Cifone, 1979, The American journal of pathology.

The biology of cancer metastasis.

I. Fidler, 2011, Seminars in cancer biology.

The importance of orthotopic implantation to the isolation and biological characterization of a metastatic human clear cell renal-carcinoma in nude-mice.

C. Dinney, I. Fidler, S. Pathak, 1993, International journal of oncology.

Expression of interferon-beta is associated with growth arrest of murine and human epidermal cells.

L. Ellis, C. Bucana, J. Arbeit, 1999, The Journal of investigative dermatology.

In vitro tumor cell destruction by syngeneic mouse macrophoages: methods for assaying cytotoxicity.

I. Fidler, K. Norbury, Isaiah J. Fidler, 1975, Journal of immunological methods.

Orthotopic implantation is essential for the selection, growth and metastasis of human renal cell cancer in nude mice [corrected].

I. Fidler, S. Pathak, S. Naito, 1990, Cancer metastasis reviews.

Advances in Brief Expression Level of the nm 23 Gene in Clonal Populations of Metastatic Murine and Human Neoplasms 1

I. Fidler, R. Radinsky, A. Staroselsky, 2006 .

Expression level of the nm23 gene in clonal populations of metastatic murine and human neoplasms.

I. Fidler, R. Radinsky, A. Staroselsky, 1992, Cancer research.

Therapy of cancer metastasis by systemic activation of macrophages: from the bench to the clinic.

I. Fidler, E. Kleinerman, 1993, Research in immunology.

Specific immunotherapy against occult cancer metastases

I. Fidler, C. Donawho, Z. Dong, 2002, International journal of cancer.

Environmental and genetic factors determine the level of NK activity of nude mice and affect their suitability as models for experimental metastasis

I. Fidler, T. Davis, N. Hanna, 1982, International journal of cancer.

Leukocyte-induced angiogenesis and subcutaneous growth of B16 melanoma.

C. Bucana, I. Fidler, K. Xie, 1994, Cancer biotherapy.

Commentary on "Tumor Heterogeneity and the Biology of Cancer Invasion and Metastasis".

I. Fidler, 2016, Cancer research.

A comparison of in vitro cell-mediated reactivity against syngeneic tumor cells by various lymphoid cell populations from Bacillus Calmette-Guérin-tumor-cured, tumor-sensitized, tumor-bearing, and normal inbred guinea pigs.

M. Hanna, I. Fidler, T. Kataoka, 1976, Cancer research.

Direct correlation between MUC18 expression and metastatic potential of human melanoma cells.

C. Bucana, I. Fidler, J. Johnson, 1993, Melanoma research.

Tumoricidal properties of mouse macrophages activated with mediators from rat lymphocytes stimulated with concanavalin A.

I. Fidler, M. B. Budmen, J. Darnell, 1976, Cancer research.

Characterization of liposomes containing the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) and their interaction with mouse macrophages.

I. Fidler, R. Nayar, K. Morikawa, 1987, Cancer drug delivery.

Direct in vitro lysis of metastatic tumor cells by cytokine-activated murine vascular endothelial cells.

G. Nicolson, I. Fidler, L. Li, 1991, Cancer research.

Macrophage-Derived Metalloelastase Is Responsible for the Generation of Angiostatin in Lewis Lung Carcinoma

I. Fidler, Rakesh Kumar, Xiulan Yang, 1997, Cell.

The biology of cancer invasion and metastasis.

D M Gersten, I. Fidler, I. Hart, 1978, Advances in cancer research.

The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis.

I. Fidler, 1973, European journal of cancer.

Cancer metastasis.

I. Fidler, I J Fidler, I. J. Fidler, 1991, British medical bulletin.

Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery.

C. Bucana, I. Fidler, G. Poste, 1982, Cancer research.

Metastatic behavior of human tumor cell lines grown in the nude mouse.

I. Fidler, M. Kaighn, I. Hart, 1984, Cancer research.

Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice.

C. Bucana, I. Fidler, J. Price, 1992, The American journal of pathology.

The potential use of liposome-mediated antiviral therapy

I. Fidler, W. Koff, Isaiah J. Fidler, 1985, Antiviral Research.

Human monocytes activated by immunomodulators in liposomes lyse herpesvirus-infected but not normal cells.

I. Fidler, W. Koff, S. Showalter, 1984, Science.

Recognition and destruction of neoplastic cells by activated macrophages: discrimination of altered self.

I. Fidler, A. Schroit, 1988, Biochimica et biophysica acta.

In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties.

I. Fidler, G. Poste, I. Hart, 1980, Cancer research.

Enhanced experimental metastasis of ultraviolet light-induced fibrosarcomas in ultraviolet light-irradiated syngeneic mice.

I. Fidler, M. Kripke, 1980, Cancer research.

Selection of successive tumour lines for metastasis.

I. Fidler, I J Fidler, 1973, Nature: New biology.

A necropsy study of canine malignant mammary neoplasms.

I. Fidler, R. Brodey, 1967, Journal of the American Veterinary Medical Association.

Direct antiproliferative effects of recombinant human interferon-alpha B/D hybrids on human tumor cell lines.

I. Fidler, I. Saiki, M. Grutter, 1987, Cancer research.

Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors.

M. Andreeff, I. Fidler, F. Marini, 2002, Cancer research.

Angiogenesis and breast cancer metastasis

L. Ellis, I. Fidler, LeeM Ellis, 1995, The Lancet.

The biology of cancer metastasis and implications for therapy.

I. Fidler, C. Balch, 1987, Current problems in surgery.

Influence of organ microenvironment on pigmentation of a metastatic murine melanoma.

I. Fidler, D. Tarin, J. Price, 1988, Cancer research.

The biology of brain metastasis.

I. Fidler, R. Langley, 2013, Clinical chemistry.

Transcriptional induction of the melanocyte-stimulating hormone receptor in brain metastases of murine K-1735 melanoma.

R. Cone, I. Fidler, R. Radinsky, 1995, Cancer research.

Biological and experimental consequences of the zonal composition of solid tumors.

I. Fidler, I. Hart, 1981, Cancer research.

Host immunity in experimental metastasis

I. Fidler, I. Hart, 1978 .

Relationship of host immune status to tumor cell arrest, distribution, and survival in experimental metastasis

I. Fidler, C. Riggs, D. Gersten, 1977, Cancer.

Expression of metastatic potential of allogenic and xenogeneic neoplasms in young nude mice.

I. Fidler, N. Hanna, 1981, Cancer research.

Design of models for testing cancer therapeutic agents

I. Fidler, Isaiah J. Fidler, Richard J. White, 1982 .

Demonstration of multiple phenotypic diversity in a murine melanoma of recent origin.

C. Bucana, I. Fidler, E. Gruys, 1981, Journal of the National Cancer Institute.

Cell surface properties of B16 melanoma variants with differing metastatic potential.

C. Bucana, I. Fidler, A. Raz, 1980, Cancer research.

Biological diversity in metastatic neoplasms: origins and implications.

I. Fidler, I. Hart, I J Fidler, 1982, Science.

Influence of immune status on the metastasis of three murine fibrosarcomas of different immunogenicities.

I. Fidler, M. Kripke, D. Gersten, 1979, Cancer research.

Tumor cell antigenicity, host immunity, and cancer metastasis

I. Fidler, M. Kripke, 2004, Cancer Immunology, Immunotherapy.

The Biological Diversity of Malignant Neoplasms

I. Fidler, M. Berendt, 1982 .

Organ selectivity for implantation survival and growth of B16 melanoma variant tumor lines.

G. Nicolson, I. Fidler, 1976, Journal of the National Cancer Institute.

Survival of hematogenously disseminated allogeneic tumor cells in athymic nude mice.

I. Fidler, S. Caines, Z. Dolan, 1976, Transplantation.

Role of the regional lymph node in neoplasia: cellular mediated reactivity in vitro by autologous regional or distant lymph nodes or peripheral blood lymphocytes of dogs with spontaneous neoplasms.

I. Fidler, S. Bech-Nielsen, M. B. Budmen, 1975, Immunological communications.

Inhibition of pulmonary metastasis by intravenous injection of specifically activated macrophages.

I. Fidler, 1974, Cancer research.

Immune stimulation-inhibition of experimental cancer metastasis.

I. Fidler, I J Fidler, 1974, Cancer research.

In vitro immune stimulation-inhibition to spontaneous canine tumors of various histologic types.

I. Fidler, R. Brodey, S. Bech-Nielsen, 1974, Journal of immunology.

In vitro studies of cellular-mediated immunostimulation of tumor growth.

I. Fidler, 1973, Journal of the National Cancer Institute.

Enhancement of experimental metastasis by x-ray: a possible mechanism.

I. Fidler, I. Zeidman, 1972, Journal of medicine.

Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes.

C. Bucana, I. Fidler, A. Schroit, 1991, Cancer research.

Effect of cytoskeleton-disrupting agents on the metastatic behavior of melanoma cells.

I. Fidler, A. Raz, I. Hart, 1980, Journal of the National Cancer Institute.

Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice.

C. Bucana, I. Fidler, R. Radinsky, 1994, Cancer research.

Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis

I. Fidler, 2004, Cancer and Metastasis Reviews.

13 – Tumorigenic and Metastatic Properties of Human Colorectal Carcinomas Transplanted into Nude Mouse

I. Fidler, J. Jessup, S. Pathak, 1990 .

The heterogeneous nature of metastatic neoplasms: implications for the treatment of cancer.

I. Fidler, J. Kozlowski, 1984, Urology.

The Use of Young Nude Mice to Study Metastasis of Human Neoplasms

I. Fidler, N. Hanna, V. Pollack, 1983 .

Correlation of growth capacity of cells in hard agarose with successful transfection by the activated c-Ha-ras oncogene and in vivo proliferative capacity at metastatic sites.

I. Fidler, H. Ananthaswamy, R. Radinsky, 1991, Anticancer research.

Biological behavior of malignant melanoma cells correlated to their survival in vivo.

I. Fidler, 1975, Cancer research.

Zonal heterogeneity for gene expression in human pancreatic carcinoma.

K. Coombes, I. Fidler, Toru Nakamura, 2007, Cancer research.

Molecular regulation of UVB-induced cutaneous angiogenesis.

C. Bucana, I. Fidler, M. Kripke, 1998, The Journal of investigative dermatology.

Biological Variability within Murine Neoplasms1

I. Fidler, M. Kripke, 1980 .

L-asparaginase and lymphocyte blastogenesis.

I. Fidler, P. Montgomery, E. Ferguson, 1971, Lancet.

The pathogenesis of cancer metastasis: Relevance to therapy

I. Fidler, Toru Nakamura, R. Langley, 2009 .

Regulation of tumor angiogenesis by organ-specific cytokines.

I. Fidler, R. Singh, 1996, Current topics in microbiology and immunology.

Metastasis as a Determinant of Risk in Breast Cancer

I. Fidler, J. Price, 1991 .

Phenotypic Heterogeneity and Metastasis

I. Fidler, J. Talmadge, 1989 .

Genetic Mechanisms in Tumor Progression, Heterogeneity, and Metastasis

I. Fidler, 1985 .

Specificity of arrest, survival, and growth of selected metastatic variant cell lines.

G. Nicolson, I. Fidler, K. Brunson, 1978, Cancer research.

TUMOR CELL SURFACES: SOME CHARACTERISTICS OF NEOPLASTIC CELLS THAT DETERMINE STATES OF TRANSFORMATION AND MALIGNANCY

G. Nicolson, I. Fidler, K. Brunson, 1977 .

The implications of tumor heterogeneity for studies on the biology and therapy of cancer metastasis

I. Fidler, I. Hart, 1981 .

Metastatic heterogeneity of cells from an ultraviolet light-induced murine fibrosarcoma of recent origin.

I. Fidler, M. Kripke, E. Gruys, 1978, Cancer research.

Immune Stimulation-Inhibition of Experimental Cancer Metastasis1

I. Fidler, 2006 .

Characterization of in vitro reactivity by BCG-treated guinea pigs to syngeneic line-10 hepatocarcinoma

M. Hanna, I. Fidler, M. B. Budmen, 2004, Cancer Immunology, Immunotherapy.

MACROPHAGE DEFICIENCY IN TUMOR BEARING ANIMALS: CONTROL OF EXPERIMENTAL METASTASIS WITH MACROPHAGES ACTIVATED IN VITRO 1

I. Fidler, 1976 .

Immunologic factors in experimental metastases formation.

I. Fidler, 1975, International journal of radiation oncology, biology, physics.

Mechanismof Tumor Cell Resistanceto Lysis by Syngeneic Lymphocytes1

C. Bucana, I. Fidler, 1977 .

Role of organ selectivity in the determination of metastatic patterns of B16 melanoma.

I. Fidler, I. Hart, I J Fidler, 1980, Cancer research.

Immunostimulation-inhibition of tumor cell growth in vitro utilizing tumor target cells labeled with 125I-iodo-deoxyuridine.

I. Fidler, 1973, Immunological communications.

The Biology of Brain Metastasis: Challenges for Therapy

I. Fidler, 2015, Cancer journal.

Biology of human colon cancer metastasis

I. Fidler, M. Gutman, 1995, World Journal of Surgery.

Critical Determinants of Human Colon Cancer Metastasis

I. Fidler, 1997 .

Treatment of the patient with lung metastases.

J. Roth, I. Fidler, R. Benjamin, 1996, Current problems in surgery.

Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor.

I. Fidler, N. Esumi, D. Fan, 1991, Cancer research.

Cancer metastasis is selective or random depending on the parent tumour population

I. Fidler, J. Talmadge, 1982, Nature.

Specifically Activated Macrophages Inhibition of Pulmonary Metastasis by Intravenous Injection of Updated

I. Fidler, 2006 .

Production of specific macrophage activating factor by lymphocytes from tumor-bearing mice.

I. Fidler, M. Kripke, M. B. Budmen, 1977, Cellular immunology.

In vitro tumor growth inhibition by syngeneic lymphocytes and/or macrophages.

I. Fidler, D. E. Peterson, 1976, Advances in experimental medicine and biology.

Macrophages and cancer

E. Kleinerman, I. Fidler, C. Pak, 1990, Cancer and Metastasis Reviews.

Effects of levamisole on in vivo and in vitro murine host response to syngeneic transplantable tumor.

I. Fidler, L. Spitler, 1975, Journal of the National Cancer Institute.

Clowes Memorial Award Lecture Critical Factors in the Biology of Human Cancer Metastasis : Updated

I. Fidler, 2006 .

Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis

I. Fidler, 1991, Cancer and Metastasis Reviews.

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture.

I. Fidler, I J Fidler, 1990, Cancer research.

Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice.

Mike Wilson, I. Fidler, S. Pathak, 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice.

I. Fidler, J. Jessup, S. Pathak, 1988, Cancer research.

Simultaneous Blockade of Platelet-Derived Growth Factor-Receptor and Epidermal Growth Factor-Receptor Signaling and Systemic Administration of Paclitaxel as Therapy for Human Prostate Cancer Metastasis in Bone of Nude Mice

I. Fidler, R. Langley, S. J. Kim, 2004, Cancer Research.

In vitro activation of murine Kupffer cells by lymphokines or endotoxins to lyse syngeneic tumor cells.

C. Bucana, I. Fidler, Z. L. Xu, 1984, The American journal of pathology.

Binding of liposomes to human bladder tumor epithelial cell lines: implications for an intravesical drug delivery system for the treatment of bladder cancer.

I. Fidler, A. V. von Eschenbach, R. Nayar, 1989, Selective cancer therapeutics.

Modification of surface topography of lymphocytes by L-asparaginase.

I. Fidler, J. Cesarini, P. C. Montgomery, 1973, Cancer research.

Constitutive production and release of a lymphokine with macrophage-activating factor activity distinct from gamma-interferon by a human T-cell leukemia virus-positive cell line.

I. Fidler, R. Gallo, P. Sarin, 1984, Cancer research.

Consistent interactions between tumor cell IL-6 and macrophage TNF-α enhance the growth of human prostate cancer cells in the bone of nude mouse.

I. Fidler, R. Langley, J. Papadopoulos, 2011, International immunopharmacology.

Critical factors in the biology of human cancer metastasis.

I. Fidler, I J Fidler, Isaiah J. Fidler, 1995, The American surgeon.

Synergistic therapy of human ovarian carcinoma implanted orthotopically in nude mice by optimal biological dose of pegylated interferon alpha combined with paclitaxel.

Suyun Huang, I. Fidler, Suyun Huang, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Metastasis and drug resistance

I. Fidler, S. J. Kim, D. Fan, 2009 .

Chromosome 14 alteration is associated with increased collagenase expression and the metastatic potential of murine melanomas.

B. Dave, I. Fidler, S. Pathak, 1996, Cancer genetics and cytogenetics.

Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis.

I. Fidler, J. Price, I J Fidler, 1991, Invasion & metastasis.

Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique.

C. Bucana, I. Fidler, A. V. von Eschenbach, 1997, The American journal of pathology.

Regulation of neoplastic angiogenesis.

I. Fidler, Isaiah J. Fidler, I. J. Fidler, 2000, Journal of the National Cancer Institute. Monographs.

Regulation of Angiogenesis by the Organ Microenvironment

I. Fidler, D. Bielenberg, 1999 .

Constitutive expression of interferon beta in differentiated epithelial cells exposed to environmental stimuli.

C. Bucana, I. Fidler, D. Bielenberg, 1998, Cancer biotherapy & radiopharmaceuticals.

Growth rate and chromosome number of tumor cell lines with different metastatic potential.

I. Fidler, M. Kripke, M. Cifone, 1979, Journal of supramolecular structure.

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells.

C. Bucana, I. Fidler, R. Radinsky, 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.

The development of liposomes containing interferon alpha for the intravesical therapy of human superficial bladder cancer.

I. Fidler, A. V. von Eschenbach, D. Fan, 1990, The Journal of urology.

The biological behavior of canine mammary neoplasms.

I. Fidler, R. Brodey, 1967, Journal of the American Veterinary Medical Association.

Synergistic activation by lymphokines and muramyl dipeptide of tumoricidal properties in rat alveolar macrophages.

I. Fidler, S. Sone, 1980, Journal of immunology.

In vitro activation of mouse macrophages by rat lymphocyte mediators.

I. Fidler, M. B. Budmen, J. Darnell, 1976, Journal of immunology.

B / D Hybrids on Human Tumor Cell Lines α Interferon-Direct Antiproliferative Effects of Recombinant Human Updated Version

I. Fidler, I. Saiki, M. Grutter, 2006 .

Mice 5-Fluorouracil on Human Colon Cancers Implanted into Nude-Interferon and γ Mechanisms of Combined Effects of Updated Version

Kiyoshi, B. Levin, I. Fidler, 2006 .

encapsulated Human Lymphokines

I. Fidler, A. Schroit, W. Fogler, 1983 .

Liposomes in the therapy of infectious diseases and cancer

I. Fidler, G. Lopez-Berestein, Geigy Pharmaceuticals, 1989 .

Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.

I. Fidler, P. Traxler, E. Buchdunger, 2000, Cancer research.

Hypo Adenosine-to-Inosine miR-455-5p Editing Promotes Melanoma Growth and Metastasis

Steven J. M. Jones, I. Birol, A. G. Robertson, 2015, Nature Cell Biology.

General concepts of tumor metastasis in the dog and cat

I. Fidler, 1976 .

Preclinical Evaluation of Individual Biological Response Modifiers

I. Fidler, J. Talmadge, R. Oldham, 1985 .

Orthotopic Models are Necessary to Predict Therapy of Transplantable Tumors in Mice

I. Fidler, R. Radinsky, J. Killion, 1998, Cancer and Metastasis Reviews.

In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice.

I. Fidler, H. Kuniyasu, C. Bruns, 1999, Neoplasia.

Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice

K. Aldape, W. Yung, I. Fidler, 2015, Clinical Cancer Research.

The "seed and soil" hypothesis revisited.

George Poste, I. Fidler, G. Poste, 2008, The Lancet. Oncology.

Tumorigenicity and metastatic behavior in nude mice of two human squamous cell carcinoma lines that differ in production of the cytokine ETAF/IL-1.

I. Fidler, J. Price, D. Sauder, 1988, The Journal of investigative dermatology.

Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model.

Kenji Yokoi, Takamitsu Sasaki, C. Bucana, 2005, Cancer research.

The molecular biology of lung cancer brain metastasis: an overview of current comprehensions and future perspectives.

I. Fidler, Y. Nishioka, M. Hanibuchi, 2014, The journal of medical investigation : JMI.

Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma.

I. Fidler, J. Gershenwald, R. Langley, 2010, Neoplasia.

Survival of cancer cells is maintained by EGFR independent of its kinase activity.

M. Hung, C. Chiu, I. Fidler, 2008, Cancer cell.

The activation of tumoricidal properties in macrophages of endotoxin responder and nonresponder mice by liposome-encapsulated immunomodulators.

I. Fidler, J. Talmadge, W. Fogler, 1983, Journal of the Reticuloendothelial Society.

The seed and soil hypothesis: vascularisation and brain metastases.

C. Bucana, I. Fidler, S. Yano, 2002, The Lancet. Oncology.

Eradication of cancer metastasis by tumoricidal macrophages.

I. Fidler, 1988, Advances in experimental medicine and biology.

Circumvention of Biologic Diversity of Cancer Metastasis

I. Fidler, 1987 .

Intracellular activation of tumoricidal properties in mouse macrophages and human monocytes by recombinant mouse or human gamma interferon encapsulated in liposomes.

I. Fidler, 1986, Annales de l'Institut Pasteur. Immunologie.

Activation of tumoricidal properties in human blood monocytes by liposomes containing lipophilic muramyl tripeptide.

I. Fidler, K. Erickson, A. Schroit, 1983, Cancer research.

The in situ induction of tumoricidal activity in alveolar macrophages by liposomes containing muramyl dipeptide is a thymus-independent process.

I. Fidler, 1981, Journal of immunology.

Therapy of autochthonous skin cancers in mice with intravenously injected liposomes containing muramyltripeptide.

I. Fidler, J. Talmadge, B. Lenz, 1986, Cancer research.

Protection of mice against fatal herpes simplex type 2 infection by liposomes containing muramyl tripeptide.

I. Fidler, W. Koff, S. Showalter, 1985, Science.

Metastatic model for human prostate cancer using orthotopic implantation in nude mice.

C. Dinney, I. Fidler, N. Ordóñez, 1992, Journal of the National Cancer Institute.

The relative mRNA expression levels of matrix metalloproteinase to E-cadherin in prostate biopsy specimens distinguishes organ-confined from advanced prostate cancer at radical prostatectomy.

D. Johnston, P. Troncoso, I. Fidler, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor/vascular permeability factor in prostatectomy specimens distinguishes organ-confined from pathologically advanced prostate cancers.

C. Bucana, D. Johnston, P. Troncoso, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Critical determinants of cancer metastasis: rationale for therapy

I. Fidler, Isaiah J. Fidler, 1999, Cancer Chemotherapy and Pharmacology.

Modulation of the cancer cell transcriptome by culture media formulations and cell density

I. Fidler, R. Langley, Sun-jin Kim, 2015, International journal of oncology.

Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice

I. Fidler, K. Haruma, K. Naka, 1999, British Journal of Cancer.

Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine.

I. Fidler, R. Langley, M. Nilsson, 2005, Cancer research.

Synchronous Overexpression of Epidermal Growth Factor Receptor and HER2-neu Protein Is a Predictor of Poor Outcome in Patients with Stage I Non-Small Cell Lung Cancer

Roy S Herbst, Waun K Hong, Arlene M Correa, 2004, Clinical Cancer Research.

Active specific immunotherapy against occult brain metastasis.

C. Bucana, I. Fidler, C. Donawho, 2003, Cancer research.

Active Specific Immunotherapy against Occult Brain Metastasis 1

C. Bucana, I. Fidler, C. Donawho, 2003 .

Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma.

I. Fidler, M A Cifone, I J Fidler, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Murine models to evaluate novel and conventional therapeutic strategies for cancer.

I. Fidler, J. Talmadge, A. Raz, 2007, The American journal of pathology.

Hematogenous metastasis of ovarian cancer: rethinking mode of spread.

Prahlad T. Ram, P. Ram, Ju-Seog Lee, 2014, Cancer cell.

Expression of interleukin-8 in human metastatic endometrial carcinoma cells and its regulation by inflammatory cytokines

C. Bucana, B. Dave, I. Fidler, 2000, International Journal of Gynecologic Cancer.

Specific keynote: molecular determinants of angiogenesis in ovarian cancer.

J. Wood, I. Fidler, Lei Xu, 2003, Gynecologic oncology.

Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer.

I. Fidler, C. Solórzano, C. Baker, 2002, Cancer research.

Metastatic Human Pancreatic Cancer Epidermal Growth Factor Receptor Signaling for Therapy of Blockade of Vascular Endothelial Growth Factor Receptor and Updated

I. Fidler, C. Solórzano, C. Baker, 2002 .

Optimization for the blockade of epidermal growth factor receptor signaling for therapy of human pancreatic carcinoma.

I. Fidler, P. Traxler, E. Buchdunger, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Expression of interleukin-8 correlates with angiogenesis, tumorigenicity, and metastasis of human prostate cancer cells implanted orthotopically in nude mice.

I. Fidler, T. Karashima, H. Uehara, 2001, Neoplasia.

Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells.

I. Fidler, I J Fidler, L Xu, 2000, Cancer research.

Regulation of disease-progression genes in human gastric carcinoma cells by interleukin 8.

I. Fidler, K. Haruma, N. Mukaida, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Differential expression of E-cadherin and type IV collagenase genes predicts outcome in patients with stage I non-small cell lung carcinoma.

C. Bucana, F. Khuri, W. Hong, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Human Ovarian Carcinoma Cells Acidic pH-induced Elevation in Interleukin 8 Expression by Updated Version

I. Fidler, Lei Xu, 2000 .

Hypoxia-induced elevation in interleukin-8 expression by human ovarian carcinoma cells.

I. Fidler, K. Matsushima, N. Mukaida, 1999, Cancer research.

Human Ovarian Carcinoma Cells Hypoxia-induced Elevation in Interleukin-8 Expression by Updated Version

I. Fidler, K. Matsushima, N. Mukaida, 1999 .

Orthotopic implantation of stomach cancer

I. Fidler, M. Mai, Yutaka Takahashi, 1997 .

Blockade of NF-κB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

C. Bucana, I. Fidler, Suyun Huang, 2001, Oncogene.

Stromal metalloproteinase-9 is essential to angiogenesis and progressive growth of orthotopic human pancreatic cancer in parabiont nude mice.

I. Fidler, Toru Nakamura, D. Fan, 2007, Neoplasia.

The role of the organ microenvironment in the biology and therapy of cancer metastasis

I. Fidler, R. Langley, Sun-jin Kim, 2007, Journal of cellular biochemistry.

The organ microenvironment and cancer metastasis.

I. Fidler, Isaiah J Fidler, 2002, Differentiation; research in biological diversity.

Contributions of stromal metalloproteinase-9 to angiogenesis and growth of human ovarian carcinoma in mice.

I. Fidler, R. Langley, Suyun Huang, 2002, Journal of the National Cancer Institute.

Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8.

C. Bucana, I. Fidler, Suyun Huang, 2000, Cancer research.

Nuclear Factor-κB Activity Correlates with Growth, Angiogenesis, and Metastasis of Human Melanoma Cells in Nude Mice

C. Bucana, I. Fidler, Suyun Huang, 2000 .

Growth Factor and Interleukin 8 Cells by Suppressing Expression of Vascular Endothelial Angiogenesis and Tumorigenicity of Human Ovarian Cancer B Signaling Inhibits κ Blockade of Nuclear Factor-Updated

C. Bucana, I. Fidler, A. Deguzman, 2000 .

Highly metastatic human prostate cancer growing within the prostate of athymic mice overexpresses vascular endothelial growth factor.

C. Dinney, I. Fidler, K. Inoue, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice.

C. Bucana, I. Fidler, H. Kuniyasu, 1998, Journal of the National Cancer Institute.

Induction of angiogenesis by hyperplastic colonic mucosa adjacent to colon cancer.

L. Ellis, C. Bucana, Mike Wilson, 2000, The American journal of pathology.

A microassay for the rapid and selective binding of cells from solid tumors to mouse macrophages

C. Bucana, I. Fidler, I. Saiki, 1986, Cancer Immunology and Immunotherapy.

Effects of L-asparaginase on lymphocyte surface and blastogenesis.

I. Fidler, P. C. Montgomery, 1972, Cancer Research.

Amplification of telomeric DNA directly correlates with metastatic potential of human and murine cancers of various histological origin.

S. Sen, I. Fidler, F. Ali-Osman, 1999, International journal of oncology.

Suppression of angiogenesis, tumorigenicity, and metastasis by human prostate cancer cells engineered to produce interferon-beta.

C. Bucana, C. Dinney, I. Fidler, 1999, Cancer research.

Review: Biologic heterogeneity of cancer metastases

I. Fidler, 1987, Breast Cancer Research and Treatment.

The seed and soil hypothesis revisited—The role of tumor‐stroma interactions in metastasis to different organs

I. Fidler, R. Langley, Isaiah J Fidler, 2011, International journal of cancer.

Critical determinants of metastasis.

I. Fidler, Isaiah J Fidler, 2002, Seminars in cancer biology.

Expression of epidermal growth factor (EGF)/transforming growth factor-α by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice

R. Herbst, I. Fidler, R. Langley, 2007, Molecular Cancer Therapeutics.

Lymphokine-activated human blood monocytes destroy tumor cells but not normal cells under cocultivation conditions.

I. Fidler, E. Kleinerman, 1984, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Spatial and temporal expression of angiogenic molecules during tumor growth and progression.

C. Bucana, R. Kumar, I. Fidler, 1998, Oncology research.

A simple quantitative assay for studying the invasive potential of high and low human metastatic variants.

M. Hendrix, I. Fidler, E. Seftor, 1987, Cancer letters.

Gene expression profile of metastatic human pancreatic cancer cells depends on the organ microenvironment.

Kevin R Coombes, K. Coombes, I. Fidler, 2007, Cancer research.

The use of molecular genetic markers to demonstrate the effect of organ environment on clonal dominance in a human renal‐cell carcinoma grown in nude mice

I. Fidler, S. Pathak, P. Frost, 1992, International journal of cancer.

Inhibition of basic fibroblast growth factor expression, angiogenesis, and growth of human bladder carcinoma in mice by systemic interferon-alpha administration.

C. Bucana, C. Dinney, I. Fidler, 1998, Cancer research.

Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas.

C. Bucana, I. Fidler, R. Singh, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Efficacy of liposomes containing a lipophilic muramyl dipeptide derivative for activating the tumoricidal properties of alveolar macrophages in vivo

I. Fidler, S. Sone, A. Schroit, 1982 .

Distribution and fate of free and liposome-encapsulated [3H]nor-muramyl dipeptide and [3H]muramyl tripeptide phosphatidylethanolamine in mice.

I. Fidler, W. Fogler, D. Brundish, 1985, Journal of immunology.

In situ activation of mouse macrophages and therapy of spontaneous renal cell cancer metastasis by liposomes containing the lipopeptide CGP 31362

C. Dinney, I. Fidler, J. Killion, 1991, Cancer Immunology, Immunotherapy.

Nonselective destruction of murine neoplastic cells by syngeneic tumoricidal macrophages.

I. Fidler, W. Fogler, 1985, Cancer research.

Isolation of tumoricidal macrophages from lung melanoma metastases of mice treated systemically with liposomes containing a lipophilic derivative of muramyl dipeptide.

C. Bucana, I. Fidler, J. Talmadge, 1982, Journal of the National Cancer Institute.

The Use of Orthotopic Models to Validate Antivascular Therapies for Cancer

I. Fidler, R. Langley, S. J. Kim, 2008 .

Cell density-dependent modulation of basic fibroblast growth factor expression by human interferon-β

C. Bucana, I. Fidler, Rakesh K. Singh, 1996 .

Interferon-beta prevents the upregulation of interleukin-8 expression in human melanoma cells.

I. Fidler, R. Singh, M. Gutman, 1996, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5‐fluorouracil

C. Bucana, I. Fidler, D. Fan, 1992, International journal of cancer.

Expression of interferon-β is associated with growth arrest of murine and human epidermal cells

L. Ellis, C. Bucana, J. Arbeit, 1999 .

Progressive growth of infantile cutaneous hemangiomas is directly correlated with hyperplasia and angiogenesis of adjacent epidermis and inversely correlated with expression of the endogenous angiogenesis inhibitor, IFN-beta.

C. Bucana, J. Mulliken, J. Folkman, 1999, International journal of oncology.

Angiogenesis and metastasis.

L. Ellis, I. Fidler, 1996, European journal of cancer.

Constitutive Expression of the α 4 Integrin Correlates with Tumorigenicity and Lymph Node Metastasis of the B16

I. Fidler, J. Gershenwald, R. Langley, 2010 .

Antivascular Therapy for Orthotopic Human Ovarian Carcinoma through Blockade of the Vascular Endothelial Growth Factor and Epidermal Growth Factor Receptors

A. Sood, I. Fidler, P. Thaker, 2005, Clinical Cancer Research.

Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells.

I. Fidler, R. Langley, Qiuyu Wu, 2014, Neuro-oncology.

Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular phase I trial in androgen-independent prostate cancer.

Peter F Thall, Paul Mathew, Christopher Logothetis, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Changes in clonal composition during in vivo growth of mixed subpopulations derived from the murine K-1735 melanoma.

I. Fidler, S. Pathak, A. Staroselsky, 1990, Anticancer research.

Development and progression of karyotypic variability in melanoma K1735 following X-irradiation.

I. Fidler, J. Talmadge, L. McMorrow, 1985, Cancer research.

Development of biological diversity and susceptibility to chemotherapy in murine cancer metastases.

I. Fidler, J. Talmadge, J. Madsen, 1984, Cancer Research.

Blastogenesis Effects of l-Asparaginase on Lymphocyte Surface and Updated Version

I. Fidler, P. C. Montgomery, 2006 .

Duration of in vivo Effects of L-Asparaginase on Experimental Metastasis

I. Fidler, 1971, Nature.

L-asparaginase and metastasis.

I. Fidler, 1970, Lancet.

Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis.

I. Fidler, R. Langley, Chenyu Zhang, 2009, International journal of oncology.

Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome in patients with resectable pancreatic carcinoma.

L. Ellis, C. Bucana, I. Fidler, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers.

M. Ferrari, I. Fidler, B. Godin, 2013, Cancer letters.

Practical considerations for the establishment of a screening procedure for the assessment of biological response modifiers.

I. Fidler, J. Talmadge, R. Oldham, 1984, Journal of biological response modifiers.

In reply [15]

C. Bucana, I. Fidler, P. Mathew, 2005 .

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis.

C. Bucana, I. Fidler, C. Pettaway, 2001, Oncogene.

A rapid colorimetric in situ mRNA hybridization technique using hyperbiotinylated oligonucleotide probes for analysis of mdr1 in mouse colon carcinoma cells.

C. Bucana, I. Fidler, R. Radinsky, 1993, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Finding the tumor copycat: Therapy fails, patients don't

L. Ellis, I. Fidler, 2010, Nature Medicine.

Cell interactions in the metastatic process: some cell surface properties associated with successful blood-borne tumor spread.

J. C. Robbins, G. Nicolson, I. Fidler, 1977, Society of General Physiologists series.

The origin of metastatic heterogeneity in tumors.

I. Fidler, I. Hart, 1981, European journal of cancer.

Production of experimental malignant pleural effusions is dependent on invasion of the pleura and expression of vascular endothelial growth factor/vascular permeability factor by human lung cancer cells.

L. Ellis, C. Bucana, R. Herbst, 2000, The American journal of pathology.

Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice.

D. Nam, I. Fidler, D. Lev, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Phase I and Pharmacologic Study of PKI166, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients with Advanced Solid Malignancies

C. Bucana, J. Verweij, I. Fidler, 2005, Clinical Cancer Research.

Targeting VEGF in Pancreatic Cancer

I. Fidler, C. Solórzano, C. Baker, 2004 .

Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases.

L. Ellis, J. Wood, I. Fidler, 2001, Cancer biotherapy & radiopharmaceuticals.

Reactive astrocytes protect melanoma cells from chemotherapy by sequestering intracellular calcium through gap junction communication channels.

K. Aldape, I. Fidler, M. Bar‐eli, 2010, Neoplasia.

Multiparametric in situ mRNA Hybridization Analysis of Gastric Biopsies Predicts Lymph Node Metastasis in Patients with Gastric Carcinoma

L. Ellis, C. Bucana, I. Fidler, 2002, Japanese journal of cancer research : Gann.

792: Therapy of Multidrug Resistant Prostate Cancer by Targeting the Epidermal Growth Factor Receptor and Vascular Endothelial Growth Factor Receptor On Tumor-Associated Endothelial Cells

I. Fidler, D. Fan, M. Yazıcı, 2006 .

Targeted therapy of orthotopic human lung cancer by combined vascular endothelial growth factor and epidermal growth factor receptor signaling blockade

R. Herbst, R. Komaki, I. Fidler, 2007, Molecular Cancer Therapeutics.

Overcoming murine tumor cell resistance to vinblastine by presentation of the drug in multilamellar liposomes consisting of phosphatidylcholine and phosphatidylserine.

I. Fidler, C. Seid, D. Fan, 1991, Selective cancer therapeutics.

The Effects of the Organ Microenvironment on Metastatic Cell Gene Signatures

J. Weinstein, Jing Wang, I. Fidler, 2017 .

Host–Tumor Interactions in Brain Cancer Metastasis Leading to Drug Resistance

I. Fidler, R. Langley, 2016 .

Neoadjuvant platelet derived growth factor receptor inhibitor therapy combined with docetaxel and androgen ablation for high risk localized prostate cancer.

P. Thall, C. Wood, I. Fidler, 2009, The Journal of urology.

Dynamic change in phosphorylated platelet-derived growth factor receptor in peripheral blood leukocytes following docetaxel therapy predicts progression-free and overall survival in prostate cancer

P. Thall, C. Bucana, M. Morris, 2008, British Journal of Cancer.

Platelet-Derived Growth Factor Receptor Inhibition and Chemotherapy for Castration-Resistant Prostate Cancer with Bone Metastases

P. Thall, C. Bucana, M. Morris, 2007, Clinical Cancer Research.

Platelet-Derived Growth Factor Receptor Inhibition and Chemotherapy for Castration-Resistant Prostate Cancer with BoneMetastases

P. Thall, C. Bucana, M. Morris, 2007 .

Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.

L. Ellis, C. Bucana, R. Herbst, 2000, Cancer research.

The brain microenvironment and cancer metastasis

I. Fidler, K. Balasubramanian, Sun-jin Kim, 2010, Molecules and cells.

Synergism between human monocyte chemotactic and activating factor and bacterial products for activation of tumoricidal properties in murine macrophages.

K. Yasumoto, I. Fidler, K. Matsushima, 1993, Journal of immunology.

Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells

C. Bucana, I. Fidler, Suyun Huang, 2002, Oncogene.

Expression of vascular endothelial growth factor by human renal cancer cells enhances angiogenesis of primary tumors and production of ascites but not metastasis to the lungs in nude mice

L. Ellis, I. Fidler, S. J. Kim, 2004, Clinical & Experimental Metastasis.

Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model.

Do-Hyun Nam, Kenji Yokoi, Stanley R Hamilton, 2005, Cancer research.

Clinical Applications of Angiogenesis Inhibitors

I. Fidler, D. Bielenberg, 1999 .

Lymphocytes are not only immunocytes.

I. Fidler, 1980, Biomedicine / [publiee pour l'A.A.I.C.I.G.].

Kinetics and ultrastructural studies of the induction of rat alveolar macrophage fusion by mediators released from mitogen-stimulated lymphocytes.

C. Bucana, I. Fidler, S. Sone, 1981, The American journal of pathology.

Species variability for toxicity of free and liposome-encapsulated muramyl peptides administered intravenously.

I. Fidler, I. Hart, N. O. Brown, 1985, Journal of biological response modifiers.

Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist.

I. Fidler, F. Lehembre, D. Fan, 2012, Translational oncology.

Targeting the tumor microenvironment (Stroma) for treatment of metastasis

I. Fidler, Toru Nakamura, R. Langley, 2008 .

Targeting platelet-derived growth factor receptor on endothelial cells of multidrug-resistant prostate cancer.

K. Do, I. Fidler, C. Logothetis, 2006, Journal of the National Cancer Institute.

The efficacy of BCG-induced tumor immunity in guinea pigs with regional and systemic malignancy

M. Hanna, I. Fidler, L. Peters, 1976, Cancer Immunology, Immunotherapy.

MORPHOLOGIC ASPECTS OF TUMOR CELL CYTOTOXICITY BY EFFECTOR CELLS OF THE MACROPHAGE-HISTIOCYTE COMPARTMENT: IN VITRO AND IN VIVO STUDIES IN BCG-MEDIATED TUMOR REGRESSION 1

M. Hanna, C. Bucana, I. Fidler, 1976 .

Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements.

I. Fidler, J. Price, S. L. Aukerman, 1986, Cancer research.

Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases.

I. Fidler, C. Logothetis, T. Karashima, 2003, Journal of the National Cancer Institute.

Role of nitric oxide in lysis of tumor cells by cytokine-activated endothelial cells.

I. Fidler, J. Adams, L. Li, 1991, Cancer research.

Search for genes that suppress cancer metastasis.

I. Fidler, R. Radinsky, 1996, Journal of the National Cancer Institute.

Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain.

L. Cantley, I. Fidler, Yan Wang, 2015, Cancer research.

Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar.

Ju-Seog Lee, I. Fidler, R. Langley, 2011, The American journal of pathology.

Circulating monocytes expressing CD31: implications for acute and chronic angiogenesis.

I. Fidler, R. Langley, J. Papadopoulos, 2009, The American journal of pathology.

Chemotherapeutic drugs—more really is not better

L. Ellis, I. Fidler, Lee M. Ellis, 2000, Nature Medicine.

Interferon-alpha-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule.

C. Dinney, I. Fidler, K. Inoue, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Angiogenic heterogeneity: regulation of neoplastic angiogenesis by the organ microenvironment.

I. Fidler, I J Fidler, 2001, Journal of the National Cancer Institute.

Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis

H. Woo, G. Mills, Ju-Seog Lee, 2011, Proceedings of the National Academy of Sciences.

Mekk3 is essential for early embryonic cardiovascular development

Melynda Boerm, Bing Su, C. Bucana, 2000, Nature Genetics.

Activation of nitric oxide synthase gene for inhibition of cancer metastasis

I. Fidler, K. Xie, Z. Dong, 1996, Journal of leukocyte biology.

The challenge of targeting metastasis

I. Fidler, M. Kripke, 2015, Cancer and Metastasis Reviews.

Oxide Synthase in Tumor-infiltrating Macrophages Associated with Enhanced Expression of Inducible Nitric Irinotecan and the Oral Immunomodulator JBT 3002 Is Therapy of Human Pancreatic Carcinoma Implants by Updated

I. Fidler, D. McConkey, D. Davis, 2000 .

Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy.

G. Mills, Ju-Seog Lee, M. Hung, 2010, Neoplasia.

Evidence for the causal role of endogenous interferon-α/β in the regulation of angiogenesis, tumorigenicity, and metastasis of cutaneous neoplasms

C. Bucana, I. Fidler, C. Donawho, 2004, Clinical & Experimental Metastasis.

Seed and soil revisited: contribution of the organ microenvironment to cancer metastasis.

I. Fidler, I J Fidler, 2001, Surgical oncology clinics of North America.

Mice by Systemic Interferon-Angiogenesis , and Growth of Human Bladder Carcinoma in Inhibition of Basic Fibroblast Growth Factor Expression

C. Dinney, I. Fidler, P. Perrotte, 2006 .

The relationship of estrous irregularity, pseudopregnancy, and pregnancy to the development of canine mammary neoplasms.

I. Fidler, A. Howson, R. Brodey, 1966, Journal of the American Veterinary Medical Association.

Relationship of estrous irregularity, pseudopregnancy, and pregnancy to canine pyometra.

I. Fidler, A. Howson, R. Brodey, 1966, Journal of the American Veterinary Medical Association.

Modulation of the organ microenvironment for treatment of cancer metastasis.

I. Fidler, I J Fidler, 1995, Journal of the National Cancer Institute.

From here to there; a life based on migration. An interview with Isaiah J. Fidler.

I. Fidler, 2004, The International journal of developmental biology.

Density-dependent induction of 92-kd type IV collagenase activity in cultures of A431 human epidermoid carcinoma cells.

C. Bucana, I. Fidler, B. Xie, 1994, American Journal of Pathology.

Angiostatin-mediated Suppression of Cancer Metastases by Primary Neoplasms Engineered to Produce Granulocyte/Macrophage Colony–stimulating Factor

I. Fidler, Rakesh Kumar, Z. Dong, 1998, The Journal of experimental medicine.

Targeting Lymphatic Metastasis

Jeffrey E Gershenwald, I. Fidler, J. Gershenwald, 2002, Science.

Tumor necrosis factor and IL-1 associated with plasma membranes of activated human monocytes lyse monokine-sensitive but not monokine-resistant tumor cells whereas viable activated monocytes lyse both.

J. Y. Tsao, Y. Ichinose, I. Fidler, 1988, Journal of immunology.

Therapy of cancer metastasis by activation of the inducible nitric oxide synthase

I. Fidler, K. Xie, 1998, Cancer and Metastasis Reviews.

Activated human blood monocytes trigger the antitumor activity of blood polymorphonuclear cells.

J. Y. Tsao, I. Fidler, S. Davis, 1989, Lymphokine research.

Cytostatic and cytolytic effects of human recombinant tumor necrosis factor on human renal cell carcinoma cell lines derived from a single surgical specimen.

Y. Ichinose, I. Fidler, S. Naito, 1987, Journal of immunology.

Biological heterogeneity of cancer

I. Fidler, Isaiah J Fidler, 2012, Human vaccines & immunotherapeutics.

Syngeneic humoral immune responses to tumor-associated antigens expressed by K-1735 UV-induced melanoma and its metastases

J. Roth, I. Fidler, D. Davidson, 1983, Cancer Immunology, Immunotherapy.

A Rapid Colorimetrie in Situ Messenger RNA Hybridization Technique for Analysis of Epidermal Growth Factor Receptor in Paraffin-embedded Surgical Specimens of Human Colon Carcinomas1

Robert, L. Ellis, I. Fidler, 2006 .

Synergism between human recombinant monocyte chemotactic and activating factor and lipopolysaccharide for activation of antitumor properties in human blood monocytes.

I. Fidler, R. Singh, 1993, Lymphokine and cytokine research.

NONSELECTIVE LYSIS OF TUMOR CELLS BY MACROPHAGES Cell Cultures

I. Fidler, W. Fogler, 2006 .

NonselectiveDestructionof MurineNeoplastiaCells by SyngeneicTumoricidal Macrophages 1

I. Fidler, W. Fogler, 2006 .

Targeting of immunomodulators to mononuclear phagocytes for therapy of cancer

I. Fidler, Isaiah J. Fidler, 1988 .

Atherosclerosis and Endothelium Biology Circulating Monocytes Expressing CD 31 Implications for Acute and Chronic Angiogenesis

I. Fidler, S. W. Kim, R. Langley, 2010 .

Optimization and limitations of systemic treatment of murine melanoma metastases with liposomes containing muramyl tripeptide phosphatidylethanolamine

I. Fidler, 1986, Cancer Immunology, Immunotherapy.

Systemic Activation of Macrophages by Liposomes Containing Muramyltripeptide Phosphatidylethanolamine for therapy of Cancer Metastasis

I. Fidler, 1990 .

Comparative interaction of free and liposome-encapsulated nor-muramyl dipeptide or muramyl tripeptide phosphatidylethanolamine (3H-labelled) with human blood monocytes.

I. Fidler, W. Fogler, 1987, International journal of immunopharmacology.

Effects of liposome structure and lipid composition on the activation of the tumoricidal properties of macrophages by liposomes containing muramyl dipeptide.

I. Fidler, A. Schroit, 1982, Cancer research.

CHAPTER 2.3 – Systemic activation of macrophages by liposomes containing synthetic immunomodulators for treatment of metastatic disease

I. Fidler, L. Worth, E. Kleinerman, 1998 .

Ultrastructural studies of the interaction between liposome-activated human blood monocytes and allogeneic tumor cells in vitro.

C. Bucana, E. Kleinerman, I. Fidler, 1983, The American journal of pathology.

Multiparametric in situ messenger RNA hybridization analysis to detect metastasis-related genes in surgical specimens of human colon carcinomas.

L. Ellis, C. Bucana, I. Fidler, 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.

Molecular Diagnosis to Predict the Metastatic Potential of Human Prostate Cancer

P. Troncoso, I. Fidler, H. Kuniyasu, 2000 .

Expression of metastasis-related genes in surgical specimens of human gastric cancer can predict disease recurrence

C. Bucana, I. Fidler, Y. Kitadai, 1998 .

Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.

C. Bucana, I. Fidler, Y. Kitadai, 1996, Differentiation; research in biological diversity.

Induction of Nitric Oxide Production and Tumoricidal Properties in Murine Macrophages by a New Synthetic Lipopeptide JBT3002 Encapsulated in Liposomes

I. Fidler, Rakesh Kumar, Z. Dong, 1998, Journal of immunotherapy.

Site-specific expression of transferrin receptor by human colon cancer cells directly correlates with eradication by antitransferrin recombinant immunotoxin.

I. Pastan, I. Fidler, S. Yano, 2000, International journal of oncology.

Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel.

Junqin He, Urs Regenass, I. Fidler, 2016, Neuro-oncology.

Regulation of distinct steps of angiogenesis by different angiogenic molecules.

C. Bucana, R. Kumar, I. Fidler, 1998, International journal of oncology.

Nitric oxide-mediated tumoricidal activity of murine microglial cells.

I. Fidler, R. Langley, E. Kruzel, 2010, Translational oncology.

Nitric Oxide-Mediated Tumoricidal Activity of

I. Fidler, S. W. Kim, R. Langley, 2010 .

Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer.

I. Fidler, F. Lehembre, Emily C. Brantley, 2011, Neoplasia.

Clonal stimulation or inhibition of human colon carcinomas and human renal carcinomas mediated by transforming growth factor-beta 1.

I. Fidler, H. Schackert, C. Seid, 1989, Cancer communications.

Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice.

I. Fidler, T. Karashima, H. Uehara, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice.

D. Nam, I. Fidler, J. Abbruzzese, 2005, Neoplasia.

Antivascular therapy of human follicular thyroid cancer experimental bone metastasis by blockade of epidermal growth factor receptor and vascular growth factor receptor phosphorylation.

C. Bucana, M. Mandal, I. Fidler, 2005, Cancer research.

Accelerated growth of human colon cancer cells in nude mice undergoing liver regeneration.

I. Fidler, J. Price, D. Fan, 1994, Invasion & metastasis.

Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells.

C. Bucana, I. Fidler, R. Radinsky, 1994, Journal of the National Cancer Institute.

Modulation of Doxorubicin sensitivity and level of p-glycoprotein expression in human colon-carcinoma cells by ectopic and orthotopic environments in nude-mice.

C. Bucana, I. Fidler, R. Radinsky, 1993, International journal of oncology.

The Nude Mouse Model for Studies of Human Cancer Metastasis

I. Fidler, 1989 .

The biology of melanoma metastasis.

I. Fidler, 1988, The Journal of dermatologic surgery and oncology.

Procedures for Preclinical Screening of Biological Response Modifying Agents

I. Fidler, J. Talmadge, R. Oldham, 1985 .

I. Fidler, J. Talmadge, J. Madsen, 2006 .

Molecular determinants of angiogenesis in cancer metastasis.

L. Ellis, R. Kumar, I. Fidler, 1998, The cancer journal from Scientific American.

Cancer Invasion and Metastasis

I. Fidler, I. Hart, 1980, The Quarterly review of biology.

The collection, purification and characterization of canine peripheral blood monocytes.

I. Fidler, I. Hart, 1979, Journal of the Reticuloendothelial Society.

Frozen-thawed human blood monocytes respond reproducibly to activation stimuli: Implications for screening of BRMs

I. Fidler, T. Utsugi, A. Nii, 1992, Biotherapy.

Treatment of experimental lung metastasis with local thoracic irradiation followed by systemic macrophage activation with liposomes containing muramyl tripeptide.

I. Fidler, L. Milas, N. Hunter, 1986, Cancer research.

Biochemical, morphological, and ultrastructural studies on the uptake of liposomes by murine macrophages.

C. Bucana, I. Fidler, G. Poste, 1981, Cancer research.

Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer.

Kevin R Coombes, John Koomen, David Hawke, 2005, International journal of oncology.

P53 mutations are infrequent and do not correlate with the metastatic potential of human-melanoma cells.

I. Fidler, R. Lenzi, M. Gutman, 1993, International journal of oncology.

The role of the organ microenvironment in brain metastasis.

I. Fidler, 2011, Seminars in cancer biology.

The activation of tumoricidal properties in human blood monocytes by muramyl dipeptide requires specific intracellular interaction.

I. Fidler, W. Fogler, 1986, Journal of immunology.

Kinetics and function of tumor cytotoxic factor(s) produced by human blood monocytes activated to the tumoricidal state.

I. Fidler, S. Sone, G. Lopez-Berestein, 1985, Journal of the National Cancer Institute.

Selective delivery of drugs encapsulated in liposomes: natural targeting to macrophages involved in various disease states.

I. Fidler, A. Schroit, I. Hart, 1983, Journal of biological response modifiers.

Pulmonary localization of intravenously injected liposomes.

I. Fidler, G. Poste, A. Raz, 1980, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

The generation of stable human T-cell hybridomas which constitutively produce interleukin-2 and chemotactic factor.

I. Fidler, K. Foon, S. Wahl, 1985, Hybridoma.

Regulatory mechanisms for the expression of type IV collagenases/gelatinases in murine macrophages.

I. Fidler, Z. Dong, I J Fidler, 1994, Journal of immunology.

Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation.

C. Bucana, I. Fidler, A. Schroit, 1989, Proceedings of the National Academy of Sciences of the United States of America.

The implications of tumor heterogeneity for studies on the biology of cancer metastasis.

I. Fidler, I. Hart, 1981, Biochimica et biophysica acta.

Systemic targeting of liposome-encapsulated immunomodulators to macrophages for treatment of cancer metastasis.

I. Fidler, J. Killion, 1994, ImmunoMethods.

Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors.

I. Fidler, R. Kerbel, Toru Nakamura, 2008, Neoplasia.

Expression of metastasis-related genes in human epithelial ovarian tumors.

K. Hess, C. Bucana, I. Fidler, 2002, International journal of oncology.

Preliminary results of a randomized placebo-controlled double-blind trial of weekly docetaxel combined with imatinib in men with metastatic androgen-independent prostate cancer (AIPC) and bone metastases (BM).

P. Thall, C. Bucana, M. Morris, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Exogenous expression of human SGLT1 exhibits aggregations in sodium dodecyl sulfate polyacrylamide gel electrophoresis.

M. Hung, I. Fidler, Yun-Ju Chen, 2013, American journal of translational research.

P-484 Synchronous overexpression of epidermal growth factor receptor and HER2-NEU is a predictor of poor outcome in patients with stage I non-small cell lung cancer

C. Bucana, W. Hong, R. Herbst, 2003 .

Circumvention of multidrug-resistance in murine fibrosarcoma and colon-carcinoma cells by treatment with the alpha-adrenoceptor antagonist furobenzazepine.

I. Fidler, G. Poste, C. Seid, 1994, International journal of oncology.

Activation of the Platelet-Derived Growth Factor-Receptor Enhances Survival of Murine Bone Endothelial Cells 1

I. Fidler, R. Langley, D. Fan, 2004, Cancer Research.

Tissue-specific microvascular endothelial cell lines from H-2K(b)-tsA58 mice for studies of angiogenesis and metastasis.

I. Fidler, R. Langley, M. Nilsson, 2003, Cancer research.

Results from Preexisting Variant Cells Within a Malignant Tumor Author ( s ) :

I. Fidler, M. Kripke, 2008 .

Critical factors regulating site-specific brain metastasis of murine melanomas.

C. Bucana, I. Fidler, K. Gohji, 1993, International journal of oncology.

Murine T-cell hybridomas that produce lymphokine with macrophage-activating factor activity as a constitutive product.

I. Fidler, K. Erickson, E. Gruys, 1982, Cellular immunology.

Modification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer model.

I. Fidler, Toru Nakamura, R. Langley, 2008, The American journal of pathology.

Effect of neuraminidase on the rat one-way mixed lymphocyte interaction.

I. Fidler, J. Kahn, P. C. Montgomery, 1973, Immunological communications.

Growth potential of human colorectal carcinomas in nude mice: association with the preoperative serum concentration of carcinoembryonic antigen in patients.

I. Fidler, J. Jessup, K. Cleary, 1988, Cancer research.

In vivo evaluation of safety of nanoporous silicon carriers following single and multiple dose intravenous administrations in mice.

M. Ferrari, I. Fidler, R. Nieves-Alicea, 2010, International journal of pharmaceutics.

Original Article Exogenous expression of human SGLT1 exhibits aggregations in sodium dodecyl sulfate polyacrylamide gel electrophoresis

M. Hung, I. Fidler, Wei Chien Huang, 2013 .

Interferons ca and 8 down-regulate the expression of basic fibroblast growth factor in human carcinomas

I. Fidler, K. Rakesh, Sánchez, 2005 .

Genomic analysis of primary tumors does not address the prevalence of metastatic cells in the population

I. Fidler, M. Kripke, 2003, Nature Genetics.

Understanding bone metastases: the key to the effective treatment of prostate cancer.

I. Fidler, 2003, Clinical advances in hematology & oncology : H&O.

Identification and validation of SRC and phospho-SRC family proteins in circulating mononuclear cells as novel biomarkers for pancreatic cancer.

Jin‐Young Jang, I. Fidler, D. Hawke, 2011, Translational oncology.

Activation of tumoricidal properties in macrophages by lymphokines encapsulated in liposomes.

I. Fidler, W. Fogler, 1982, Lymphokine research.

Prostaglandin E2 does not inhibit tumoricidal activity of mouse macrophages against adherent tumor cells.

I. Fidler, T. Utsugi, 1991, Journal of immunology.

Neoplastic angiogenesis--not all blood vessels are created equal.

Lee M Ellis, L. Ellis, I. Fidler, 2004, The New England journal of medicine.

Differential release of TNF-alpha, IL 1, and PGE2 by human blood monocytes subsequent to interaction with different bacterial derived agents.

I. Fidler, T. Utsugi, O. Bakouche, 1990, Lymphokine research.

Mechanisms of cancer metastasis.

I. Fidler, J. Killion, 1989, Arzneimittel-Forschung.

The role of plasma membrane receptors and the kinetics of macrophage activation by lymphokines encapsulated in liposomes.

I. Fidler, G. Poste, A. Raz, 1981, Cancer research.

Preface to the ‘UKCCCR guidelines for the Welfare of animals in experimental neoplasia’

I. Fidler, 2004, Cancer and Metastasis Reviews.

Level of protein kinase C activity correlates directly with resistance to adriamycin in murine fibrosarcoma cells

I. Fidler, C. Seid, D. Fan, 1989, FEBS letters.

The pathogenesis of cancer metastasis. (review).

I. Fidler, G. Poste, 1980 .

Depression of macrophages in mice drinking hyperchlorinated water

I. Fidler, ISAIAH J. FIDLER, 1977, Nature.

Abstract 601: Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer

I. Fidler, F. Lehembre, S. J. Kim, 2011 .

Dual inhibition of the epidermal growth factor and vascular endothelial growth factor phosphorylation for antivascular therapy of human prostate cancer in the prostate of nude mice

I. Fidler, P. Thaker, D. Fan, 2005, The Prostate.

Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice.

D. Nam, I. Fidler, D. Lev, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Integrated Systems and Technologies Cancer Research Integrated Profiling Reveals a Global Correlation between Epigenetic and Genetic Alterations in Mesothelioma

R. M. Simpson, B. Christensen, C. Marsit, 2010 .

Discussion: Metastasis and Angiogenesis in Epithelial Ovarian Cancer

G. Mills, D. Fishman, E. Kohn, 2003 .

UICC study group in basic and clinical cancer research: Cancer metastasis

I. Fidler, M. Burger, 1984, International journal of cancer.

Cancer biology is the foundation for therapy

I. Fidler, 2005, Cancer biology & therapy.

Activation of tumoricidal properties in macrophages by lipopolysaccharide requires protein‐tyrosine kinase activity

I. Fidler, Z. Dong, C. O'Brian, 1993, Journal of leukocyte biology.

Intratumoral heterogeneity for and epigenetic modulation of mdr-1 expression in murine melanoma

C. Bucana, I. Fidler, Y. Wang, 1997, Melanoma research.

Angiogenesis and cancer metastasis: antiangiogenic therapy of human pancreatic adenocarcinoma

I. Fidler, C. Solórzano, C. Baker, 2001, International Journal of Clinical Oncology.

Breast Cancer Research and Treatment 2001 Reviewers

D. Berry, L. Holmberg, D. Alberts, 2004, Breast Cancer Research and Treatment.

Liposomes containing muramyl tripeptide phosphatidylethanolamine (MTP‐PE) are excellent adjuvants for induction of an immune response to protein and tumor antigens

I. Fidler, S. Ullrich, Isaiah J. Fidler, 1992, Journal of leukocyte biology.

Angiogenesis and growth of murine colon carcinoma are dependent on infiltrating leukocytes.

C. Bucana, I. Fidler, J. Yoneda, 1999, Cancer biotherapy & radiopharmaceuticals.

The therapeutic effect of human recombinant macrophage colony stimulating factor (CSF-1) in experimental murine metastatic melanoma.

D. Hume, I. Fidler, R. Donahue, 1989, Lymphokine research.

The effects of intravenous administration of Methanol Extraction Residue (MER) of tubercle bacilli in the dog

M. Hanna, I. Fidler, J. Gutterman, 2004, Cancer Immunology, Immunotherapy.

AACR centennial series: the biology of cancer metastasis: historical perspective.

I. Fidler, J. Talmadge, 2010, Cancer research.

ARD1 Stabilization of TSC2 Suppresses Tumorigenesis Through the mTOR Signaling Pathway

M. Hung, S. Tsai, I. Fidler, 2010, Science Signaling.

Neoadjuvant platelet derived growth factor receptor inhibitor therapy combined with docetaxel and androgen ablation for high risk localized prostate cancer.

P. Thall, C. Wood, I. Fidler, 2009, The Journal of urology.

Tissue-specific microvascular endothelial cell lines from H-2K(b)-tsA58 mice for studies of angiogenesis and metastasis.

I. Fidler, R. Langley, M. Nilsson, 2003, Cancer research.

Cancer Invasion and Metastasis

I. Fidler, I. Hart, 1980, The Quarterly Review of Biology.

MACROPHAGE DEFICIENCY IN TUMOR BEARING ANIMALS: CONTROL OF EXPERIMENTAL METASTASIS WITH MACROPHAGES ACTIVATED IN VITRO11Research sponsored by the National Cancer Institute under Contract No. N01-C0–25423 with Litton Bionetics, Incorporated.

I. Fidler, 1976 .

Vascular Biology, Atherosclerosis and Endothelium Biology Circulating Monocytes Expressing CD31 Implications for Acute and Chronic Angiogenesis

I. Fidler, R. Langley, J. Papadopoulos, 2022 .

Interferon‐alpha prevents selection of doxorubicin‐resistant undifferentiated‐androgen‐insensitive metastatic human prostate cancer cells

I. Fidler, H. Kuniyasu, N. Oue, 2001, The Prostate.

In situ activation of mouse lung macrophages by coadministration of liposomes containing the lipopeptide CGP 31362 and interleukin 2 involves interaction with T lymphocytes and natural killer cells.

C. Dinney, I. Fidler, J. Killion, 1991, Lymphokine and cytokine research.

Superior antiproliferative effects mediated by interferon-alpha entrapped in liposomes against a newly established human lung cancer cell line.

C. Bucana, I. Fidler, D. Shin, 1990, Journal of biological response modifiers.

Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells.

I. Fidler, R. Langley, Qiuyu Wu, 2014, Neuro-oncology.

Advances in Brief Elevated Expression of Phosphatidylserine in the Outer Membrane Leaflet of Human Tumor Cells and Recognition by Activated Human Blood Monocytes 1

I. Fidler, A. Schroit, T. Utsugi, 2006 .

Abstract 3428: Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy

G. Mills, I. Fidler, R. Langley, 2010 .