C. Stevenson

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Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation.

Christopher S. Stevenson, D. Richardson, C. Stevenson, 2007, American journal of physiology. Lung cellular and molecular physiology.

BET Bromodomain Proteins Mediate Downstream Signaling Events following Growth Factor Stimulation in Human Lung Fibroblasts and Are Involved in Bleomycin-Induced Pulmonary Fibrosis

Carla M. T. Bauer, Christopher S. Stevenson, C. Stevenson, 2013, Molecular Pharmacology.

Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis.

C. Stevenson, C. Hogaboam, Xiaoyan Tang, 2013, The American journal of pathology.

Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue.

Christopher S. Stevenson, J. Hogg, A. Phillion, 2017, Journal of applied physiology.

Bleomycin induced lung fibrosis increases work of breathing in the mouse.

C. Stevenson, R. Peng, J. Phillips, 2012, Pulmonary pharmacology & therapeutics.

Targeting the SYK-BTK axis for the treatment of immunological and hematological disorders: recent progress and therapeutic perspectives.

Christopher S. Stevenson, Seng-Lai Tan, C. Stevenson, 2013, Pharmacology & therapeutics.

Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions

Joshua D. Campbell, Christopher S. Stevenson, C. Stevenson, 2018, Nature Communications.

Effect of adenosine A2A receptor activation in murine models of respiratory disorders.

Christopher S. Stevenson, C. Stevenson, S. Ferretti, 2006, American journal of physiology. Lung cellular and molecular physiology.

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression

Matthew S. Walters, R. Crystal, C. Stevenson, 2013, Epigenetics & Chromatin.

IL-17A and the Promotion of Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Carla M. T. Bauer, Christopher S. Stevenson, C. Stevenson, 2015, American journal of respiratory and critical care medicine.

Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs.

Irfan Rahman, Christopher S. Stevenson, W. MacNee, 2004, American journal of respiratory cell and molecular biology.

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice.

Christopher S. Stevenson, I. Adcock, C. Stevenson, 2009, American journal of respiratory and critical care medicine.

Preclinical animal models of asthma and chronic obstructive pulmonary disease

Christopher S. Stevenson, C. Stevenson, M. Belvisi, 2008, Expert review of respiratory medicine.

In vivo modeling systems for chronic obstructive pulmonary disease

Christopher S. Stevenson, C. Stevenson, D. Underwood, 2006 .

Predicting drug efficacy using integrative models for chronic respiratory diseases.

C. Stevenson, S. Sridhar, J. Phillips, 2013, Inflammation & allergy drug targets.

In Vivo Models of Inflammation

Christopher S. Stevenson, C. Stevenson, L. Marshall, 1999, Progress in Inflammation Research.

Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice

Carla M. T. Bauer, Christopher S. Stevenson, C. Stevenson, 2016, Infection and Immunity.

Correction: Cigarette Smoke Induced Airway Inflammation Is Independent of NF-κB Signalling

Christopher S. Stevenson, I. Adcock, T. Lawrence, 2013, PLoS ONE.

Resolving the spatial and cellular architecture of lung adenocarcinoma by multiregion single-cell sequencing.

Christopher S. Stevenson, L. Tran, P. Scheet, 2021, Cancer discovery.

Scytonemin-a marine natural product inhibitor of kinases key in hyperproliferative inflammatory diseases

Christopher S. Stevenson, C. Stevenson, W. Gerwick, 2002, Inflammation Research.

Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect.

Helinor J Johnston, Christopher S. Stevenson, C. Stevenson, 2005, American Journal of Physiology - Lung cellular and Molecular Physiology.

Current smoking status is associated with reduced sputum immunoglobulin M and G expression in COPD

Rongchang Chen, C. Stevenson, Yuqiong Yang, 2020, European Respiratory Journal.

Pharmacologic targeting of the ATX/LPA axis attenuates bleomycin-induced pulmonary fibrosis.

Christopher S. Stevenson, V. Aidinis, C. Stevenson, 2018, Pulmonary pharmacology & therapeutics.

Discovery of highly selective and orally active lysophosphatidic acid receptor-1 antagonists with potent activity on human lung fibroblasts.

Christopher S. Stevenson, C. Stevenson, A. Narayanan, 2012, Journal of medicinal chemistry.

Inhaled Dose Translation from Rodent to Human: A Retrospective Analysis of Mometasone Furoate

C. Stevenson, J. Phillips, H. Roché, 2012 .

Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs

Christopher S. Stevenson, W. MacNee, C. Stevenson, 2010, Journal of Inflammation.

P2X7 Receptor and Caspase 1 Activation Are Central to Airway Inflammation Observed after Exposure to Tobacco Smoke

Christopher S. Stevenson, C. Stevenson, M. Belvisi, 2011, PloS one.

House dust mite models: will they translate clinically as a superior model of asthma?

C. Stevenson, R. Peng, C. Bauer, 2013, The Journal of allergy and clinical immunology.

Discovery of novel non-carboxylic acid 5-amino-4-cyanopyrazole derivatives as potent and highly selective LPA1R antagonists.

C. Stevenson, V. Roongta, A. Sidduri, 2014, Bioorganic & medicinal chemistry letters.

The Identification and Characterization of the Marine Natural Product Scytonemin as a Novel Antiproliferative Pharmacophore

William H Gerwick, Christopher S. Stevenson, Robert S Jacobs, 2002, Journal of Pharmacology and Experimental Therapeutics.

Bleomycin Induces Molecular Changes Directly Relevant to Idiopathic Pulmonary Fibrosis: A Model for “Active” Disease

Carla M. T. Bauer, Christopher S. Stevenson, C. Stevenson, 2013, PloS one.

Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients

P. Scheet, J. Minna, I. Wistuba, 2021, Cancers.

Role of the Inflammasome-Caspase1/11-IL-1/18 Axis in Cigarette Smoke Driven Airway Inflammation: An Insight into the Pathogenesis of COPD

Christopher S. Stevenson, C. Stevenson, M. Belvisi, 2014, PloS one.

Edinburgh Research Explorer Cigarette Smoke Exposure Alters mSin3a and Mi-2alpha/beta Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function

Christopher S. Stevenson, I. Adcock, K. Chung, 2010 .

Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function

Christopher S. Stevenson, I. Adcock, K. Chung, 2010, Journal of Inflammation.

Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition.

Christopher S. Stevenson, W. MacNee, C. Stevenson, 2006, American journal of physiology. Lung cellular and molecular physiology.

Single-cell analysis of human lung epithelia reveals concomitant expression of the SARS-CoV-2 receptor ACE2 with multiple virus receptors and scavengers in alveolar type II cells

P. Scheet, J. Minna, I. Wistuba, 2020, bioRxiv.

Btk Inhibitor RN983 Delivered by Dry Powder Nose-only Aerosol Inhalation Inhibits Bronchoconstriction and Pulmonary Inflammation in the Ovalbumin Allergic Mouse Model of Asthma.

Christopher S. Stevenson, C. Stevenson, R. Peng, 2016, Journal of aerosol medicine and pulmonary drug delivery.

Intraflagellar Transport Gene Expression Associated with Short Cilia in Smoking and COPD

Christopher S. Stevenson, R. Crystal, C. Stevenson, 2014, PloS one.

Comprehensive Stereological assessment of the human lung using multi-resolution computed tomography.

Christopher S. Stevenson, G. Verleden, J. Hogg, 2020, Journal of applied physiology.

Is intrinsic aerobic exercise capacity a determinant of COPD susceptibility?

Christopher S. Stevenson, C. Stevenson, Liang Yew-Booth, 2013, Pulmonary pharmacology & therapeutics.

Persistence of circulating endothelial microparticles in COPD despite smoking cessation

Christopher S. Stevenson, J. Mezey, R. Crystal, 2016, Thorax.

Pharmacological characterisation of anti-inflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation

Christopher S. Stevenson, C. Stevenson, D. Wyss, 2010, Respiratory research.

Distinguishing smoking related lung disease phenotypes via imaging and molecular features.

Christopher S. Stevenson, E. Regan, R. Bowler, 2020, Chest.

Moving towards a new generation of animal models for asthma and COPD with improved clinical relevance.

Christopher S. Stevenson, C. Stevenson, M. Birrell, 2011, Pharmacology & therapeutics.

Aerobic capacity, oxidant stress, and chronic obstructive pulmonary disease--a new take on an old hypothesis.

Christopher S. Stevenson, C. Stevenson, L. Koch, 2006, Pharmacology & therapeutics.

Pathological Comparisons of Paraseptal and Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease

J. Hogg, H. Coxson, C. Stevenson, 2020 .

Antigen-induced mast cell expansion and bronchoconstriction in a mouse model of asthma.

Christopher S. Stevenson, C. Stevenson, J. Phillips, 2014, American journal of physiology. Lung cellular and molecular physiology.

Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD

Donavan T. Cheng, Carla M. T. Bauer, Christopher S. Stevenson, 2012, Mucosal Immunology.

Persistence of Smoking-Induced Dysregulation of MiRNA Expression in the Small Airway Epithelium Despite Smoking Cessation

Hans Bitter, Jason G. Mezey, Ronald G. Crystal, 2015, PloS one.

Respiratory Infections Cause the Release of Extracellular Vesicles: Implications in Exacerbation of Asthma/COPD

Christopher S. Stevenson, C. Stevenson, M. Belvisi, 2014, PloS one.

The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in COPD

Christopher S. Stevenson, D. Sin, H. Coxson, 2021, European Respiratory Journal.

Increased Monocyte-Derived CD11b+ Macrophage Subpopulations Following Cigarette Smoke Exposure Are Associated With Impaired Bleomycin-Induced Tissue Remodelling

Christopher S. Stevenson, C. Stevenson, M. Stämpfli, 2021, Frontiers in Immunology.

Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions

C. Stevenson, Gang Liu, M. Lenburg, 2018, bioRxiv.

Chronic obstructive pulmonary disease susceptibility: Is it due to poor oxygen metabolism?

Christopher S. Stevenson, C. Stevenson, 2009 .

Comparison of Cigarette Smoke-Induced Acute Inflammation in Multiple Strains of Mice and the Effect of a Matrix Metalloproteinase Inhibitor on These Responses

Christopher S. Stevenson, C. Stevenson, D. Wyss, 2008, Journal of Pharmacology and Experimental Therapeutics.

Cigarette Smoke Exposure as a Model of Inflammation Associated with COPD

Christopher S. Stevenson, C. Stevenson, M. Birrell, 2013, Current protocols in pharmacology.

Cigarette Smoke Induced Airway Inflammation Is Independent of NF-κB Signalling

Christopher S. Stevenson, I. Adcock, T. Lawrence, 2013, PloS one.