J. Marwick

发表

Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation.

Christopher S. Stevenson, D. Richardson, C. Stevenson, 2007, American journal of physiology. Lung cellular and molecular physiology.

Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression.

I. Rahman, J. Marwick, P. Kirkham, 2004, Biochemical pharmacology.

Biomarkers in Lung Diseases: from Pathogenesis to Prediction to New Therapies Glycogen synthase kinase-3 modulation of glucocorticoid responsiveness in COPD

R. Hoffmann, M. Lindsay, I. Adcock, 2016 .

Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway

J. Marwick, C. Haslett, R. Duffin, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis

F. Goñi, J. Marwick, M. Egeblad, 2020, Nature Communications.

A role for phosphoinositol 3-kinase delta in the impairment of glucocorticoid responsiveness in patients with chronic obstructive pulmonary disease.

I. Adcock, K. Chung, J. Marwick, 2010, The Journal of allergy and clinical immunology.

Fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease: 5-year follow-up.

L. Fabbri, J. Marwick, M. Contoli, 2010, The Journal of allergy and clinical immunology.

The oncogene Gankyrin is expressed in testicular cancer and contributes to cisplatin sensitivity in embryonal carcinoma cells

N. Carragher, J. Marwick, L. Looijenga, 2019, BMC Cancer.

A role for PI 3 Kδ in the impairment of glucocorticoid responsiveness in COPD 1 2

I. Adcock, K. Chung, J. Marwick, 2015 .

Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF‐κB activation and proinflammatory cytokine release in alveolar epithelial cells

I. Rahman, J. Marwick, I. Kilty, 2004 .

Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation

J. Marwick, I. Dransfield, N. Hirani, 2018, Cell Death & Disease.

Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs.

Irfan Rahman, Christopher S. Stevenson, W. MacNee, 2004, American journal of respiratory cell and molecular biology.

Oxidants Induce a Corticosteroid-Insensitive Phosphorylation of Histone 3 at Serine 10 in Monocytes

K. Chung, J. Marwick, P. Bhavsar, 2015, PloS one.

Molecular mechanisms of oxidative stress in airways and lungs with reference to asthma and chronic obstructive pulmonary disease

J. Marwick, K. Chung, 2010, Annals of the New York Academy of Sciences.

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice.

Christopher S. Stevenson, I. Adcock, C. Stevenson, 2009, American journal of respiratory and critical care medicine.

Cigarette Smoke‐Induced Oxidative Stress and TGF‐β1 Increase p21waf1/cip1 Expression in Alveolar Epithelial Cells

W. MacNee, I. Rahman, J. Marwick, 2002 .

Cigarette smoke-induced oxidative stress and TGF-beta1 increase p21waf1/cip1 expression in alveolar epithelial cells.

W. MacNee, I. Rahman, J. Marwick, 2002, Annals of the New York Academy of Sciences.

Corticosteroids: use and insensitivity in severe asthma

I. Adcock, K. Chung, J. Marwick, 2011 .

Mechanisms of corticosteroid resistance in severe asthma and chronic obstructive pulmonary disease (COPD).

I. Adcock, K. Chung, J. Marwick, 2010, Current pharmaceutical design.

Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments

J. Marwick, C. Haslett, C. Ward, 2013, Journal of leukocyte biology.

Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis

J. Marwick, I. Dransfield, N. Barth, 2018, The Journal of Immunology.

Edinburgh Research Explorer A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis

Eld, F. Goñi, J. Marwick, 2020 .

Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs

Christopher S. Stevenson, W. MacNee, C. Stevenson, 2010, Journal of Inflammation.

Overcoming Reduced Glucocorticoid Sensitivity in Airway Disease

I. Adcock, K. Chung, J. Marwick, 2010, Drugs.

Functional characterisation of human pulmonary monocyte-like cells in lipopolysaccharide-mediated acute lung inflammation

J. Marwick, K. Dhaliwal, M. Brittan, 2014, Journal of Inflammation.

Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2.

P. Chakravarty, I. Rahman, J. Marwick, 2008, American journal of respiratory cell and molecular biology.

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung

J. Marwick, C. Haslett, R. Duffin, 2013, Mucosal Immunology.

Technical Advance: Autofluorescence-based sorting: rapid and nonperturbing isolation of ultrapure neutrophils to determine cytokine production

Christopher Haslett, Kevin Dhaliwal, Adriano G. Rossi, 2013, Journal of leukocyte biology.

Application of a High-Content Screening Assay Utilizing Primary Human Lung Fibroblasts to Identify Antifibrotic Drugs for Rapid Repurposing in COVID-19 Patients

John C. Dawson, N. Carragher, J. Marwick, 2021, SLAS Discovery.

Phosphatidylinositol 3-kinase isoforms as targets in respiratory disease

I. Adcock, K. Chung, J. Marwick, 2010, Therapeutic advances in respiratory disease.

The impact of cigarette smoke on cell survival and inflammation in rat lungs : the role of oxidative stress and VEGF/KDR signalling and its implications in COPD

J. Marwick, John A. Marwick, 2005 .

The “Phagocytic Synapse” and Clearance of Apoptotic Cells

Marc Vendrell, Adriano G. Rossi, Ian Dransfield, 2017, Front. Immunol..

Glucocorticoid insensitivity as a future target of therapy for chronic obstructive pulmonary disease.

K. Chung, J. Marwick, 2010, International journal of chronic obstructive pulmonary disease.

Edinburgh Research Explorer Cigarette Smoke Exposure Alters mSin3a and Mi-2alpha/beta Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function

Christopher S. Stevenson, I. Adcock, K. Chung, 2010 .

Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function

Christopher S. Stevenson, I. Adcock, K. Chung, 2010, Journal of Inflammation.

Glucocorticoid insensitivity as a future target of therapy for chronic obstructive pulmonary disease

K. Chung, J. Marwick, John A. Marwick, 2010, International journal of chronic obstructive pulmonary disease.

Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-kappaB activation and proinflammatory cytokine release in alveolar epithelial cells.

I. Rahman, J. Marwick, I. Kilty, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition.

Christopher S. Stevenson, W. MacNee, C. Stevenson, 2006, American journal of physiology. Lung cellular and molecular physiology.

Cyclin-dependent kinases 7 and 9 specifically regulate neutrophil transcription and their inhibition drives apoptosis to promote resolution of inflammation

J. Marwick, C. Haslett, R. Duffin, 2012, Cell Death and Differentiation.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES: Molecular mechanisms of oxidative stress in airways and lungs with reference to asthma and chronic obstructive pulmonary disease: Oxidative stress in asthma and COPD

K. Chung, J. Marwick, 2010 .

Oxidative stress modulates theophylline effects on steroid responsiveness.

Bernhard Kuster, Probir Chakravarty, Kazuhiro Ito, 2008, Biochemical and biophysical research communications.

Oxidative stress and steroid resistance in asthma and COPD: pharmacological manipulation of HDAC-2 as a therapeutic strategy

I. Adcock, J. Marwick, P. Kirkham, 2007, Expert opinion on therapeutic targets.

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

F. Tacke, C. Weston, J. Marwick, 2019, Nature.

Acute caffeine intake influences central more than peripheral blood pressure in young adults.

D. Webb, J. Marwick, S. Maxwell, 2003, American journal of hypertension.

Resolving the fibrotic niche of human liver cirrhosis at single cell level

C. Ponting, S. Teichmann, J. Marioni, 2019, Nature.