Qiaojun He

Qiaojun He, Bo Yang, Like Zhong, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The molecular mechanisms and targeting strategies of transcription factors in cholangiocarcinoma

Qiaojun He, Hong Zhu, Jiao Wang, 2022, Expert opinion on therapeutic targets.

Bortezomib sensitizes human osteosarcoma cells to adriamycin‐induced apoptosis through ROS‐dependent activation of p‐eIF2α/ATF4/CHOP axis

Ning Zhang, Qiaojun He, Bo Yang, 2017, International journal of cancer.

Small Molecule Therapeutics Tirapazamine Sensitizes Hepatocellular Carcinoma Cells to Topoisomerase I Inhibitors via Cooperative Modulation of Hypoxia-Inducible Factor-1 a

Qiaojun He, Bo Yang, Ji Cao, 2014 .

Tirapazamine Sensitizes Hepatocellular Carcinoma Cells to Topoisomerase I Inhibitors via Cooperative Modulation of Hypoxia-Inducible Factor-1α

Qiaojun He, Bo Yang, Ji Cao, 2013, Molecular Cancer Therapeutics.

GL3, a Novel 4β-Anilino-4'-O-Demethyl-4-Desoxypodophyllotoxin Analog, Traps Topoisomerase II Cleavage Complexes and Exerts Anticancer Activities.

Qiaojun He, Bo Yang, Ji Cao, 2013, Translational oncology.

Analog, Traps Topoisomerase II Cleavage Complexes and Exerts Anticancer Activities 1

Qiaojun He, Bo Yang, Ji Cao, 2013 .

Structure-activity relationship of Citrus segment membrane RG-I pectin against Galectin-3: The galactan is not the only important factor.

Qiaojun He, R. Linhardt, Shiguo Chen, 2020, Carbohydrate polymers.

JAK-STAT signaling as an ARDS therapeutic target: Status and future trends.

Qiaojun He, P. Luo, Xiaochun Yang, 2022, Biochemical pharmacology.

Homoisoflavonoids from Ophiopogon japonicus

Qiaojun He, Bo Yang, L. Gan, 2013 .

Novel hybrids from lamellarin D and combretastatin A 4 as cytotoxic agents.

Qiaojun He, Bo Yang, Yongzhou Hu, 2010, European journal of medicinal chemistry.

Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-based Design.

Qiaojun He, Bo Yang, Yongzhou Hu, 2019, Journal of medicinal chemistry.

Synthesis and evaluation of novel 5-sulfonyl-indolin-2-ones as potent cytotoxic agents

Qiaojun He, Bo Yang, Yu Luo, 2011 .

Synthesis and cytotoxicity of indolopyrrolemaleimides.

Qiaojun He, Bo Yang, Yongzhou Hu, 2007, Chemical & pharmaceutical bulletin.

Nitrogen-containing flavonoids as CDK1/Cyclin B inhibitors: design, synthesis, and biological evaluation.

Qiaojun He, Bo Yang, Yongzhou Hu, 2007, Bioorganic & medicinal chemistry letters.

Novel combretastatin A-4 derivative XN0502 induces cell cycle arrest and apoptosis in A549 cells

Qiaojun He, Bo Yang, Yongzhou Hu, 2010, Investigational New Drugs.

MZ3 induces apoptosis in human leukemia cells

Qiaojun He, Bo Yang, Yongzhou Hu, 2006, Cancer Chemotherapy and Pharmacology.

Design, synthesis, and quantitative structure-activity relationship of cytotoxic gamma-carboline derivatives.

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Bioorganic & medicinal chemistry.

Q39, a novel synthetic Quinoxaline 1,4-Di-N-oxide compound with anti-cancer activity in hypoxia.

Qiaojun He, Bo Yang, Yongzhou Hu, 2008, European journal of pharmacology.

Synthesis, hypoxia-selective cytotoxicity of new 3-amino-1,2,4-benzotriazine-1,4-dioxide derivatives.

Qiaojun He, Bo Yang, Yongzhou Hu, 2011, European journal of medicinal chemistry.

Simultaneous Quantification and Pharmacokinetic Study of Five Homologs of Dalbavancin in Rat Plasma Using UHPLC-MS/MS

Qiaojun He, Qinjie Weng, L. Ping, 2020, Molecules.

Synthesis and Antitumor Activity of Novel 4-Chloro-3-Arylmaleimide Derivatives

Qiaojun He, Bo Yang, Yongzhou Hu, 2009 .

Ougan (Citrus reticulata cv. Suavissima) flavedo extract suppresses cancer motility by interfering with epithelial-to-mesenchymal transition in SKOV3 cells

Kun-song Chen, Qiaojun He, Bo Yang, 2015, Chinese Medicine.

Keratinocytes apoptosis contributes to crizotinib induced-erythroderma.

Xueqin Chen, Qiaojun He, Bo Yang, 2019, Toxicology letters.

Potential of Compounds Originating from the Nature to Act in Hepatocellular Carcinoma Therapy by Targeting the Tumor Immunosuppressive Microenvironment: A Review

Qiaojun He, Xiaochun Yang, Yunheng Li, 2022, Molecules.

All-Trans Retinoic Acid Prevents Osteosarcoma Metastasis by Inhibiting M2 Polarization of Tumor-Associated Macrophages

Qiaojun He, Bo Yang, Ji Cao, 2017, Cancer Immunology Research.

2‐Bromopalmitate sensitizes osteosarcoma cells to adriamycin‐induced apoptosis via the modulation of CHOP

Ning Zhang, Qiaojun He, Bo Yang, 2019, European journal of pharmacology.

Design, synthesis and AChE inhibitory activity of indanone and aurone derivatives.

Bo Yang, Jing Zhang, Yongzhou Hu, 2009, European journal of medicinal chemistry.

Synthesis and In‐Vitro Antitumor Activities of Some Mannich Bases of 9‐Alkyl‐1,2,3,4‐tetrahydrocarbazole‐1‐ones

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Archiv der Pharmazie.

Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism

Qiaojun He, Bo Yang, Xiaowu Dong, 2019, Front. Physiol..

Progress and perspective of organoid technology in cancer-related translational medicine.

Li Jiang, Qiaojun He, Ji Cao, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Ubiquitin–proteasome system-targeted therapy for uveal melanoma: what is the evidence?

Qiaojun He, Bo Yang, Ke Wang, 2020, Acta Pharmacologica Sinica.

The participation of non-canonical autophagic proteins in the autophagy process and their potential as therapeutic targets

Qiaojun He, P. Luo, Xiaochun Yang, 2023, Expert opinion on therapeutic targets.

s-HBEGF/SIRT1 circuit-dictated crosstalk between vascular endothelial cells and keratinocytes mediates sorafenib-induced hand–foot skin reaction that can be reversed by nicotinamide

Xueqin Chen, Qiaojun He, Ji Cao, 2020, Cell Research.

Epigenetic strategies synergize with PD-L1/PD-1 targeted cancer immunotherapies to enhance antitumor responses

Qiaojun He, Bo Yang, L. Ding, 2019, Acta pharmaceutica Sinica. B.

Macrophage Polarization: Anti‐Cancer Strategies to Target Tumor‐Associated Macrophage in Breast Cancer

Qiaojun He, Bo Yang, L. Ding, 2017, Journal of cellular biochemistry.

Butein suppresses PD-L1 expression via downregulating STAT1 in non-small cell lung cancer.

Qiaojun He, Qinjie Weng, Ling Ding, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Novel quinoline-derived mTOR inhibitors with remarkable enzymatic and cellular activities: design, synthesis and biological evaluation

Qiaojun He, Bo Yang, Yongzhou Hu, 2016 .

GDC-0941 sensitizes breast cancer to ABT-737 in vitro and in vivo through promoting the degradation of Mcl-1.

Qiaojun He, Bo Yang, N. Lin, 2011, Cancer letters.

XN05, a novel synthesized microtubule inhibitor, exhibits potent activity against human carcinoma cells in vitro.

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Cancer letters.

MZ3 can induce G2/M-phase arrest and apoptosis in human leukemia cells

Qiaojun He, Bo Yang, Yongzhou Hu, 2008, Journal of Cancer Research and Clinical Oncology.

Synthesis and biological evaluation of 3,4-diaryl-5-aminoisoxazole derivatives.

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Bioorganic & medicinal chemistry.

Potent antitumor activity of 10-methoxy-9-nitrocamptothecin

W. Lu, Qiaojun He, Bo Yang, 2006, Molecular Cancer Therapeutics.

Antiangiogenesis response of endothelial cells to the antitumour drug 10-methoxy-9-nitrocamptothecin.

Qiaojun He, Bo Yang, P. Luo, 2006, Pharmacological research.

Targeting Microglia and Macrophages: A Potential Treatment Strategy for Multiple Sclerosis

Qiaojun He, Bo Yang, Jincheng Wang, 2019, Front. Pharmacol..

Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization

Qiaojun He, L. Fang, Jiajia Wang, 2018, Cell Death & Disease.

Human osteosarcoma CD49f−CD133+ cells: impaired in osteogenic fate while gain of tumorigenicity

Qiaojun He, W. May, Lingtao Wu, 2012, Oncogene.

New Insights of CCR7 Signaling in Dendritic Cell Migration and Inflammatory Diseases

Qiaojun He, Jiajia Wang, Qinjie Weng, 2022, Frontiers in Pharmacology.

Abrogation of Akt signaling by Isobavachalcone contributes to its anti-proliferative effects towards human cancer cells.

Qiaojun He, Bo Yang, Ji Cao, 2010, Cancer letters.

Ubiquitin-dependent degradation of CDK2 drives the therapeutic differentiation of AML by targeting PRDX2.

Qiaojun He, Bo Yang, Ji Cao, 2018, Blood.

Emerging views of OPTN (optineurin) function in the autophagic process associated with disease

Qiaojun He, Jincheng Wang, Jiajia Wang, 2021, Autophagy.

The role of autophagy in targeted therapy for acute myeloid leukemia

Qiaojun He, Bo Yang, Ji Cao, 2020, Autophagy.

Targeting PI3K/AKT signaling for treatment of idiopathic pulmonary fibrosis

Qiaojun He, Jincheng Wang, Jiajia Wang, 2021, Acta pharmaceutica Sinica. B.

cGAS and cancer therapy: a double-edged sword

Qiaojun He, Bo Yang, Hong Zhu, 2022, Acta Pharmacologica Sinica.

AKT inhibitor Hu7691 induces differentiation of neuroblastoma cells

Qiaojun He, Ji Cao, Xiaowu Dong, 2023, Acta pharmaceutica Sinica. B.

Intrinsic and acquired resistance to CDK4/6 inhibitors and potential overcoming strategies

Qiaojun He, Bo Yang, L. Ding, 2020, Acta Pharmacologica Sinica.

Dasatinib synergises with irinotecan to suppress hepatocellular carcinoma via inhibiting the protein synthesis of PLK1

Qiaojun He, Bo Yang, P. Luo, 2017, British Journal of Cancer.

Research Status and Outlook of PD-1/PD-L1 Inhibitors for Cancer Therapy

Qiaojun He, P. Luo, Leilei Ai, 2020, Drug design, development and therapy.

Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis.

Xinran Dong, P. Blackshear, B. Aronow, 2019, Cell stem cell.

Regulation of p53 stability as a therapeutic strategy for cancer.

Qiaojun He, P. Luo, Hao Yan, 2021, Biochemical pharmacology.

PARP1 Suppresses the Transcription of PD-L1 by Poly(ADP-Ribosyl)ating STAT3

Qiaojun He, Bo Yang, L. Ding, 2018, Cancer Immunology Research.

Aldo–Keto Reductase AKR1C1–AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy

Qiaojun He, Bo Yang, Ji Cao, 2017, Front. Pharmacol..

Cellular Senescence and Anti-Cancer Therapy.

Qiaojun He, Bo Yang, Ji Cao, 2019, Current drug targets.

The Proteasome Inhibitor Bortezomib Enhances ATRA-Induced Differentiation of Neuroblastoma Cells via the JNK Mitogen-Activated Protein Kinase Pathway

Qiaojun He, Bo Yang, P. Luo, 2011, PloS one.

WSB1 regulates c-Myc expression through β-catenin signaling and forms a feedforward circuit

Qiaojun He, Bo Yang, Ji Cao, 2021, Acta pharmaceutica Sinica. B.

Targeting Myc Interacting Proteins as a Winding Path in Cancer Therapy

Qiaojun He, Ji Cao, Bo Yang, 2021, Frontiers in Pharmacology.

WSB1 Regulates c-Myc Expression Through β-catenin Signaling and Forms a Feedforward Circuit Promoting the Development of Cancer

Qiaojun He, Bo Yang, Ji Cao, 2020, bioRxiv.

Post-translational modification of KRAS: potential targets for cancer therapy

Jin-jian Lu, Qiaojun He, Bo Yang, 2020, Acta Pharmacologica Sinica.

Kelch-like proteins: physiological functions and relationships with diseases.

Qiaojun He, Bo Yang, Ji Cao, 2019, Pharmacological research.

The regulatory and modulatory roles of TRP family channels in malignant tumors and relevant therapeutic strategies

Qiaojun He, Ling Ding, Bo Yang, 2021, Acta pharmaceutica Sinica. B.

Post-translational modification of retinoic acid receptor alpha and its roles in tumor cell differentiation.

Qiaojun He, Bo Yang, Ji Cao, 2019, Biochemical pharmacology.

A mechanism-based fluorescent probe for labeling O6-methylguanine-DNA methyltransferase in live cells.

Qiaojun He, Bo Yang, Yongzhou Hu, 2012, Organic & biomolecular chemistry.

Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy

Qiaojun He, Bo Yang, Yongbo Liu, 2021, Nature Chemical Biology.

MSFTZ, a Flavanone Derivative, Induces Human Hepatoma Cell Apoptosis via a Reactive Oxygen Species- and Caspase-Dependent Mitochondrial Pathway

Qiaojun He, Bo Yang, Yongzhou Hu, 2008, Journal of Pharmacology and Experimental Therapeutics.

DJ-1 suppresses ferroptosis through preserving the activity of S-adenosyl homocysteine hydrolase

Li Jiang, Qiaojun He, Bo Yang, 2020, Nature Communications.

PROTAC-DB 2.0: an updated database of PROTACs

Qiaojun He, Dan Li, Tingjun Hou, 2022, Nucleic Acids Res..

CPT21, a novel compound with anti-proliferative effect against gastric cancer cell SGC7901

Qiaojun He, Bo Yang, Wei Lu, 2008, Investigational New Drugs.

Hyperglycemia decreases anti-cancer efficiency of Adriamycin via AMPK pathway.

Yunxi Liu, Qiaojun He, Bo Yang, 2018, Endocrine-related cancer.

Antiproliferation in human EA.hy926 endothelial cells and inhibition of VEGF expression in PC-3 cells by topotecan.

Qiaojun He, Bo Yang, Meidan Ying, 2007, Die Pharmazie.

DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide.

Qiaojun He, Bo Yang, Jincheng Wang, 2019, European journal of pharmacology.

Exploration of the Use of Natural Compounds in Combination with Chemotherapy Drugs for Tumor Treatment

Qiaojun He, Xiaochun Yang, Yunheng Li, 2023, Molecules.

PROTAC-DB: an online database of PROTACs

Dong-Sheng Cao, Dan Li, Tingjun Hou, 2020, Nucleic Acids Res..

Hepatotoxicity of FDA-approved small molecule kinase inhibitors

Qiaojun He, Bo Yang, Ying Jin, 2020, Expert opinion on drug safety.

The posttranslational modifications of Hippo-YAP pathway in cancer.

Qiaojun He, Bo Yang, Hong Zhu, 2019, Biochimica et biophysica acta. General subjects.

Synergistic antitumor effect of TRAIL in combination with sunitinib in vitro and in vivo.

W. Lu, Qiaojun He, Bo Yang, 2010, Cancer letters.

Nutlin-3 inhibits epithelial-mesenchymal transition by interfering with canonical transforming growth factor-β1-Smad-Snail/Slug axis.

Qiaojun He, Bo Yang, Yeping Wu, 2014, Cancer letters.

Inhibition of KLF4 by Statins Reverses Adriamycin-Induced Metastasis and Cancer Stemness in Osteosarcoma Cells

Qiaojun He, Meidan Ying, Bo Yang, 2017, Stem cell reports.

Cardiovascular toxicity induced by anti-VEGF/VEGFR agents: a special focus on definitions, diagnoses, mechanisms and management

Qiaojun He, P. Luo, L. Ping, 2020, Expert opinion on drug metabolism & toxicology.

Tumor hypoxia enhances non-small cell lung cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling

Qiaojun He, Bo Yang, Ji Cao, 2014, Oncotarget.

Inhibition of all‐Trans‐retinoic acid‐induced proteasome activation potentiates the differentiating effect of retinoid in acute myeloid leukemia cells

Qiaojun He, Bo Yang, Yan-fen Fang, 2011, Molecular carcinogenesis.

A Comprehensive Review of Clinical Cardiotoxicity Incidence of FDA-Approved Small-Molecule Kinase Inhibitors

Qiaojun He, Ying Jin, P. Luo, 2020, Frontiers in Pharmacology.

Vascular endothelial growth factor (VEGF) antibody significantly increases the risk of hand–foot skin reaction to multikinase inhibitors (MKIs): A systematic literature review and meta‐analysis

Qiaojun He, P. Luo, Yi Zhu, 2018, Clinical and experimental pharmacology & physiology.

Cyclin-dependent kinases-based synthetic lethality: Evidence, concept, and strategy

Qian Wu, Qiaojun He, Bo Yang, 2021, Acta pharmaceutica Sinica. B.

LncRNA-MM2P Identified as a Modulator of Macrophage M2 Polarization

Li Jiang, Qiaojun He, Bo Yang, 2018, Cancer Immunology Research.

Oxidative stress is involved in Dasatinib-induced apoptosis in rat primary hepatocytes.

Qiaojun He, Bo Yang, P. Luo, 2012, Toxicology and applied pharmacology.

One therapeutic approach for triple-negative breast cancer: Checkpoint kinase 1 inhibitor AZD7762 combination with neoadjuvant carboplatin.

Qiaojun He, Bo Yang, Ji Cao, 2021, European journal of pharmacology.

Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L.

W. Lu, Qiaojun He, Bo Yang, 2010, Cancer letters.

Stress granule: A promising target for cancer treatment

Li Jiang, Qiaojun He, Bo Yang, 2019, British journal of pharmacology.

Efficient activation of p53 pathway in A549 cells exposed to L2, a novel compound targeting p53–MDM2 interaction

Qiaojun He, Bo Yang, Ji Cao, 2009, Anti-cancer drugs.

High-mobility group box 1 protein-mediated necroptosis contributes to dasatinib-induced cardiotoxicity.

Qiaojun He, Bo Yang, Q. Shi, 2018, Toxicology letters.

Neohesperidin Prevents Colorectal Tumorigenesis by Altering the Gut Microbiota.

Li Jiang, Qiaojun He, Bo Yang, 2019, Pharmacological research.

The involvement of M2 macrophage polarization inhibition in fenretinide-mediated chemopreventive effects on colon cancer.

Qiaojun He, Bo Yang, Ji Cao, 2017, Cancer letters.

All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damage

Qiaojun He, Bo Yang, P. Luo, 2016, BMC Cancer.

Intrinsic Retinoic Acid Receptor α‐Cyclin‐Dependent Kinase‐Activating Kinase Signaling Involves Coordination of the Restricted Proliferation and Granulocytic Differentiation of Human Hematopoietic Stem Cells

T. Triche, Qiaojun He, Lingtao Wu, 2007, Stem cells.

Development and safety of PI3K inhibitors in cancer

Qiaojun He, P. Luo, Xiaochun Yang, 2023, Archives of Toxicology.

ROS-dependent DNA damage contributes to crizotinib-induced hepatotoxicity via the apoptotic pathway.

Xueqin Chen, Qiaojun He, Bo Yang, 2019, Toxicology and applied pharmacology.

Canagliflozin primes antitumor immunity by triggering PD-L1 degradation in endocytic recycling

Qiaojun He, Ji Cao, Jianguo Feng, 2023, The Journal of clinical investigation.

Recent advance of peptide-based molecules and nonpeptidic small-molecules modulating PD-1/PD-L1 protein-protein interaction or targeting PD-L1 protein degradation.

Qiaojun He, Xiaowu Dong, Yang Lu, 2021, European journal of medicinal chemistry.

Sequential treatment with aurora B inhibitors enhances cisplatin-mediated apoptosis via c-Myc

Qiaojun He, Meidan Ying, Siyue Lou, 2015, Journal of Molecular Medicine.

HIF-1α-dependent autophagy protects HeLa cells from fenretinide (4-HPR)-induced apoptosis in hypoxia.

Qiaojun He, Bo Yang, Ji Cao, 2010, Pharmacological research.

Crosstalk between alveolar macrophages and alveolar epithelial cells/fibroblasts contributes to the pulmonary toxicity of gefitinib.

Qiaojun He, P. Luo, Ziye Zhou, 2020, Toxicology letters.

Diosmetin protects against retinal injury via reduction of DNA damage and oxidative stress

Qiaojun He, Bo Yang, P. Luo, 2015, Toxicology reports.

DNA-PKcs, a novel functional target of acriflavine, mediates acriflavine's p53-dependent synergistic anti-tumor efficiency with melphalan.

Qiaojun He, Bo Yang, Ji Cao, 2016, Cancer letters.

IL-2K35C-moFA, a Long-Acting Engineered Cytokine with Decreased Interleukin 2 Receptor α Binding, Improved the Cellular Selectivity Profile and Antitumor Efficacy in a Mouse Tumor Model

Qiaojun He, L. Nie, Hai-bin Wang, 2022, Cancers.

Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells.

Ning Zhang, Bo Yang, Rong Dong, 2015, Cancer research.

Targeting Cul3-scaffold E3 ligase complex via KLHL substrate adaptors for cancer therapy.

Qiaojun He, Bo Yang, Ji Cao, 2021, Pharmacological research.

Antileukemia activity of MSFTZ–a novel flavanone analog

Qiaojun He, Bo Yang, Yongzhou Hu, 2006, Anti-cancer drugs.

TSNAD v2.0: A one-stop software solution for tumor-specific neoantigen detection

Qiaojun He, Shuqing Chen, Jingcheng Wu, 2021, Computational and structural biotechnology journal.

Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein Sip1 Is Required for Myelination in the Central Nervous System

Elliott H. Sherr, Polina Bukshpun, Qiaojun He, 2012, Neuron.

Dietary pectic substances enhance gut health by its polycomponent: A review.

Qiaojun He, R. Linhardt, Tian Ding, 2021, Comprehensive reviews in food science and food safety.

Synthesis and hypoxic-cytotoxic activity of some 3-amino-1,2,4-benzotriazine-1,4-dioxide derivatives.

Qiaojun He, Bo Yang, Yongzhou Hu, 2006, Bioorganic & medicinal chemistry letters.

Synthesis, Structure and Hypoxic Cytotoxicity of 3‐Amino‐1,2,4‐benzotriazine‐1,4‐dioxide Derivatives

Qiaojun He, Bo Yang, Yongzhou Hu, 2007, Archiv der Pharmazie.

Protective effects and possible mechanisms of Centella asiatica (L.) urban extract against acute and chronic liver injury: Evidence from in vivo and in vitro studies

Qiaojun He, Yue-ting Wu, Renhua Gai, 2021, Phytotherapy research : PTR.

Synthesis and biological evaluation of novel 2-arylamino-3-(arylsulfonyl)quinoxalines as PI3Kα inhibitors.

Qiaojun He, Bo Yang, Yongzhou Hu, 2011, European journal of medicinal chemistry.

Deneddylation of PML/RARα reconstructs functional PML nuclear bodies via orchestrating phase separation to eradicate APL

Qiaojun He, Ji Cao, Meidan Ying, 2022, Cell Death & Differentiation.

Role of DJ-1 in Immune and Inflammatory Diseases

Qiaojun He, Bo Yang, Jincheng Wang, 2020, Frontiers in Immunology.

VEGF and Bcl-2 Interact Via MAPKs Signaling Pathway in the Response to Hypoxia in Neuroblastoma

Qiaojun He, Bo Yang, Duo-duo Wang, 2009, Cellular and Molecular Neurobiology.

MDM2 promotes epithelial–mesenchymal transition and metastasis of ovarian cancer SKOV3 cells

Qiaojun He, Bo Yang, Dan-dan Wang, 2017, British Journal of Cancer.

Phosphorylation regulates cullin-based ubiquitination in tumorigenesis

Qiaojun He, Bo Yang, Ji Cao, 2020, Acta pharmaceutica Sinica. B.

Autophagy blockade sensitizes the anticancer activity of CA-4 via JNK-Bcl-2 pathway.

Qiaojun He, Bo Yang, P. Luo, 2014, Toxicology and applied pharmacology.

STAT3 dictates β-cell apoptosis by modulating PTEN in streptozocin-induced hyperglycemia

Qiaojun He, Bo Yang, Meidan Ying, 2019, Cell Death & Differentiation.

Discovery of novel 2-piperidinol-3-(arylsulfonyl)quinoxalines as phosphoinositide 3-kinase α (PI3Kα) inhibitors.

Qiaojun He, Bo Yang, Yongzhou Hu, 2012, Bioorganic & medicinal chemistry.

Function of retinoid acid receptor α and p21 in all-trans-retinoic acid-induced acute T-lymphoblastic leukemia apoptosis

Qiaojun He, Meihua Lin, P. Luo, 2009, Leukemia & lymphoma.

Noncovalent CDK12/13 dual inhibitors-based PROTACs degrade CDK12-Cyclin K complex and induce synthetic lethality with PARP inhibitor

Li Jiang, Qiaojun He, Ji Cao, 2021, European Journal of Medicinal Chemistry.

Genetic dominance of transforming growth factor-β1 polymorphisms in chronic liver disease

Qiaojun He, Jiajia Wang, Qinjie Weng, 2022, Frontiers in Immunology.

Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression

Qiaojun He, Bo Yang, Xiaowu Dong, 2021, Acta pharmaceutica Sinica. B.

A novel indole derivative compound GY3 improves glucose and lipid metabolism via activation of AMP-activated protein kinase pathway.

Qiaojun He, Youyou Yan, Honghai Wu, 2013, European journal of pharmacology.

Design, Synthesis and Evaluation of Indene Derivatives as Retinoic Acid Receptor α Agonists

Qiaojun He, Yongzhou Hu, Huazhou Ying, 2016, Molecules.

Dihydromyricetin prevents cardiotoxicity and enhances anticancer activity induced by adriamycin

Qiaojun He, Bo Yang, P. Luo, 2014, Oncotarget.

Multi-constraint molecular generation based on conditional transformer, knowledge distillation and reinforcement learning

Tingjun Hou, Benben Liao, Jike Wang, 2021, Nature Machine Intelligence.

Determination of lansoprazole in human plasma by rapid resolution liquid chromatography-electrospray tandem mass spectrometry: application to a bioequivalence study on Chinese volunteers.

Qiaojun He, Bo Yang, Hui-li Zhou, 2008, Journal of pharmaceutical and biomedical analysis.

ASFP (Artificial Intelligence based Scoring Function Platform): a web server for the development of customized scoring functions

Gaoang Wang, Tingjun Hou, Gaoqi Weng, 2021, Journal of Cheminformatics.

Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling

Qiaojun He, Bo Yang, Ji Cao, 2021, Nature Communications.

Design, synthesis, and biological evaluation of quinazoline derivatives with covalent reversible warheads as potential FGFR4 inhibitors.

Qiaojun He, Xiaowu Dong, Yang Lu, 2022, Bioorganic chemistry.

SDHA/B reduction promotes hepatocellular carcinoma by facilitating the deNEDDylation of cullin1 and stabilizing YAP/TAZ

Qiaojun He, Xin Dong, Hong Zhu, 2022, Hepatology.

TCF7L2 activation is required for myelin regeneration in 5-FU-induced demyelinating mice

Qiaojun He, Bo Yang, X. Yang, 2015 .

5-Fluorouracil causes severe CNS demyelination by disruption of TCF7L2/HDAC1/HDAC2 complex in adolescent mice.

Qiaojun He, Bo Yang, Hui Zhou, 2014, Toxicology.

Gefitinib Synergizes with Irinotecan to Suppress Hepatocellular Carcinoma via Antagonizing Rad51-Mediated DNA-Repair

Qiaojun He, Bo Yang, P. Luo, 2016, PloS one.

HMGB1 contributes to adriamycin-induced cardiotoxicity via up-regulating autophagy.

Qiaojun He, Bo Yang, P. Luo, 2018, Toxicology letters.

CDK2 suppression synergizes with all-trans-retinoic acid to overcome the myeloid differentiation blockade of AML cells.

Qiaojun He, Bo Yang, Ji Cao, 2019, Pharmacological research.

Toxicological Risk Assessments of Iron Oxide Nanocluster- and Gadolinium-Based T1MRI Contrast Agents in Renal Failure Rats.

Qiaojun He, Bo Yang, T. Hyeon, 2019, ACS nano.

Q6, a novel hypoxia-targeted drug, regulates hypoxia-inducible factor signaling via an autophagy-dependent mechanism in hepatocellular carcinoma

Qiaojun He, Bo Yang, Ji Cao, 2013, Autophagy.

Upregulation of histone acetylation reverses organic anion transporter 2 repression and enhances 5-fluorouracil sensitivity in hepatocellular carcinoma.

Qiaojun He, Bo Yang, S. Zeng, 2021, Biochemical pharmacology.

COVID-19 epidemic: a special focus on diagnosis, complications, and management

Qiaojun He, P. Luo, Leilei Ai, 2020, Expert review of clinical pharmacology.

Mevalonate improves anti-PD-1/PD-L1 efficacy by stabilizing CD274 mRNA

Qiaojun He, Xi Chen, Ling Ding, 2023, Acta pharmaceutica Sinica. B.

Design, synthesis and evaluation of flavonoid derivatives as potent AChE inhibitors.

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Bioorganic & medicinal chemistry.

Evaluation of Artificial Intelligence in Participating Structure-Based Virtual Screening for Identifying Novel Interleukin-1 Receptor Associated Kinase-1 Inhibitors

Qiaojun He, Bo Yang, Xiaowu Dong, 2020, Frontiers in Oncology.

Advances in differentiation therapy for osteosarcoma.

Qiaojun He, Bo Yang, Ji Cao, 2020, Drug discovery today.

Synthesis and evaluation of water-soluble docetaxel prodrugs-docetaxel esters of malic acid.

Qiaojun He, Bo Yang, Yongzhou Hu, 2007, Bioorganic & medicinal chemistry.

Correction: Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells

Qiaojun He, Bo Yang, Ji Cao, 2020, Cancer Research.

YQ36: A Novel Bisindolylmaleimide Analogue Induces KB/VCR Cell Death

Qiaojun He, Bo Yang, Ji Cao, 2010, Journal of biomedicine & biotechnology.

DeepAtomicCharge: a new graph convolutional network-based architecture for accurate prediction of atomic charges

Lei Xu, Dongsheng Cao, Bo Yang, 2020, Briefings Bioinform..

Multikinase Inhibitor CT-707 Targets Liver Cancer by Interrupting the Hypoxia-Activated IGF-1R-YAP Axis.

Qiaojun He, Bo Yang, Ji Cao, 2018, Cancer research.

Synergistic antitumor activity of regorafenib and rosuvastatin in colorectal cancer

Qiaojun He, Hong Zhu, Wen-Cheng Kong, 2023, Frontiers in Pharmacology.

DJ-1 suppresses ferroptosis through preserving the activity of S-adenosyl homocysteine hydrolase

Li Jiang, Qiaojun He, Bo Yang, 2020, Nature Communications.

An update on Alectinib: a first line treatment for ALK-positive advanced lung cancer

Qiaojun He, P. Luo, Yiming Yin, 2023, Expert opinion on pharmacotherapy.

The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer

Qiaojun He, Bo Yang, Ji Cao, 2020, Theranostics.

Autophagy plays an important role in sunitinib-mediated cell death in H9c2 cardiac muscle cells.

Qiaojun He, Bo Yang, Hong Zhu, 2010, Toxicology and applied pharmacology.

Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity

Qiaojun He, Jiajia Wang, Q. Lu, 2017, Scientific Reports.

Norcantharidin analogues — Synthesis and evaluation of growth inhibition in a panel of selected tumor-cell lines

Qiaojun He, Bo Yang, Yongzhou Hu, 2007 .

Deubiquitination complex platform: A plausible mechanism for regulating the substrate specificity of deubiquitinating enzymes

Li Jiang, Qiaojun He, Ji Cao, 2023, Acta pharmaceutica Sinica. B.

N-myristoylation: from cell biology to translational medicine

Qiaojun He, Bo Yang, Ji Cao, 2020, Acta Pharmacologica Sinica.

Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein Sip1 Is Required for Myelination in the Central Nervous System

Qiaojun He, D. Huylebroeck, W. Shou, 2012, Neuron.

SSizer: Determining the Sample Sufficiency for Comparative Biological Study.

Yang Zhang, Ying Zhou, Feng Zhu, 2020, Journal of molecular biology.

A practical "preTACs-cytoblot" platform accelerates the streamlined development of PROTAC-based protein degraders.

Li Jiang, Qiaojun He, Xiaowu Dong, 2023, European journal of medicinal chemistry.

PTX3 from vascular endothelial cells contributes to trastuzumab-induced cardiac complications

Xueqin Chen, Qiaojun He, P. Luo, 2023, Cardiovascular research.

Synthesis and biological evaluation of novel flavonoid derivatives as dual binding acetylcholinesterase inhibitors.

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Journal of enzyme inhibition and medicinal chemistry.

Design, synthesis and biological evaluation of quinazoline derivatives as potent and selective FGFR4 inhibitors.

Qiaojun He, Xiaowu Dong, Yang Lu, 2021, European journal of medicinal chemistry.

Hypoxia promotes etoposide (VP-16) resistance in neuroblastoma CHP126 cells.

Qiaojun He, Bo Yang, Duo-duo Wang, 2010, Die Pharmazie.

Synthesis and biological evaluation of novel flavonoid derivatives as dual binding acetylcholinesterase inhibitors

Qiaojun He, Bo Yang, Yongzhou Hu, 2009 .

Design, synthesis and evaluation of galanthamine derivatives as acetylcholinesterase inhibitors.

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, European journal of medicinal chemistry.

Cytotoxic Diterpenoids from the Stem Bark of Annona squamosa L.

Qiaojun He, Bo Yang, Hong Zhu, 2013 .

Regorafenib inhibits EphA2 phosphorylation and leads to liver damage via the ERK/MDM2/p53 axis

Xueqin Chen, Qiaojun He, P. Luo, 2023, Nature communications.

KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells

Qiaojun He, Bo Yang, L. Fang, 2018, Acta Pharmacologica Sinica.

Bisdemethoxycurcumin attenuates cisplatin-induced renal injury through anti-apoptosis, anti-oxidant and anti-inflammatory.

Xueqin Chen, Qiaojun He, Bo Yang, 2020, European journal of pharmacology.

Discovery of Novel Indazoles as Potent and Selective PI3Kδ Inhibitors with High Efficacy for Treatment of Hepatocellular Carcinoma.

Qiaojun He, Hong Zhu, Sunliang Cui, 2022, Journal of medicinal chemistry.

ASFP (AI-based Scoring Function Platform): a web server for the development of customized scoring functions

Qiaojun He, Tingjun Hou, Zhe Wang, 2020 .

Nutlin-1 strengthened anti-proliferation and differentiation-inducing activity of ATRA in ATRA-treated p-glycoprotein deregulated human myelocytic leukemia cells

Qiaojun He, Bo Yang, Weisi Wang, 2012, Investigational New Drugs.

Crizotinib induces pulmonary toxicity by blocking autophagy flux in alveolar epithelial cells.

Qiaojun He, P. Luo, Xiaochun Yang, 2023, Biochemical Pharmacology.

Deubiquitinating enzymes: promising targets for drug resistance.

Qiaojun He, Hong Zhu, Yulian Wu, 2022, Drug discovery today.

4,5-Diaryl-3-aminopyrazole Derivatives as Analogues of Combretastatin A-4: Synthesis and Biological Evaluation.

J. Chen, Qiaojun He, Bo Yang, 2011 .

Retinoid-suppressed phosphorylation of RARα mediates the differentiation pathway of osteosarcoma cells

Ximing J. Yang, T. Triche, Qiaojun He, 2010, Oncogene.

Dasatinib Causes Keratinocyte Apoptosis Via Inhibiting High Mobility Group Box 1-mediated Mitophagy.

Qiaojun He, P. Luo, F. Jiang, 2022, Toxicology letters.

Macrophage Polarization: Anti‐Cancer Strategies to Target Tumor‐Associated Macrophage in Breast Cancer

Qiaojun He, Ling Ding, Gui-kai Liang, 2017, Journal of cellular biochemistry.

Cancer-associated fibroblasts drive early pancreatic cancer cell invasion via the SOX4/MMP11 signalling axis.

Qiaojun He, Hong Zhu, Hongyu Zhang, 2023, Biochimica et biophysica acta. Molecular basis of disease.

Strategies to Synergize PD-1/PD-L1 Targeted Cancer Immunotherapies to Enhance Antitumor Responses in Ovarian Cancer.

Qiaojun He, Ling Ding, Honghai Wu, 2023, Biochemical pharmacology.

Autophagy contributes to dasatinib-induced myeloid differentiation of human acute myeloid leukemia cells.

Qiaojun He, Bo Yang, Ji Cao, 2014, Biochemical pharmacology.

STAT3 dictates β-cell apoptosis by modulating PTEN in streptozocin-induced hyperglycemia

Qiaojun He, Bo Yang, Meidan Ying, 2019, Cell Death & Differentiation.

Deubiquitinating enzyme JOSD2 affects susceptibility of NSCLC cells to anti-cancer drugs through DNA damage repair.

Qiaojun He, Hong Zhu, T. Yuan, 2023, Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences.

MSFTZ, a Flavanone Derivative, Induces Human Hepatoma Cell Apoptosis via a Reactive Oxygen Species- and Caspase-Dependent Mitochondrial Pathway

Qiaojun He, Bo Yang, Yongzhou Hu, 2008, Journal of Pharmacology and Experimental Therapeutics.

Chloroquine Intervenes Nephrotoxicity of Nilotinib through Deubiquitinase USP13‐Mediated Stabilization of Bcl‐XL

Qiaojun He, P. Luo, Xiaochun Yang, 2023, Advanced science.

KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells

Qiaojun He, Bo Yang, Qiao-jun He, 2018, Acta Pharmacologica Sinica.

DNA-PKcs, a novel functional target of acriflavine, mediates acriflavine's p53-dependent synergistic anti-tumor efficiency with melphalan.

Qiaojun He, Bo Yang, Ji Cao, 2016, Cancer letters.

TEMPORARY REMOVAL: Crizotinib induces pulmonary toxicity by blocking autophagy flux in alveolar epithelial cells

Qiaojun He, P. Luo, Xiaochun Yang, 2023, Biochemical Pharmacology.

A novel indole derivative compound GY3 improves glucose and lipid metabolism via activation of AMP-activated protein kinase pathway.

Qiaojun He, Youyou Yan, Honghai Wu, 2013, European journal of pharmacology.

Hyperglycemia decreases anti-cancer efficiency of Adriamycin via AMPK pathway.

Yunxi Liu, Qiaojun He, Bo Yang, 2018, Endocrine-related cancer.

Inhibition of PRKAA/AMPK (Ser485/491) phosphorylation by crizotinib induces cardiotoxicity via perturbing autophagosome-lysosome fusion

Qiaojun He, P. Luo, Xiaochun Yang, 2023, Autophagy.