Isobel S Okoye

发表

Comprehensive in vitro characterization of PD-L1 small molecule inhibitors

Lai Xu, A. Ganesan, Marawan Ahmed, 2019, Scientific Reports.

Sex Matters: Physiological Abundance of Immuno-Regulatory CD71+ Erythroid Cells Impair Immunity in Females

Isobel S Okoye, S. Elahi, P. Koleva, 2021, Frontiers in Immunology.

Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminths

Isobel S Okoye, F. Brombacher, Stephanie Czieso, 2017, The Journal of experimental medicine.

Epithelial cell alarmin cytokines: Frontline mediators of the asthma inflammatory response

Isobel S Okoye, Paige Lacy, M. Duchesne, 2022, Frontiers in Immunology.

CD4+ T helper 2 cells – microbial triggers, differentiation requirements and effector functions

Isobel S Okoye, Mark S. Wilson, M. Wilson, 2011, Immunology.

E2 ubiquitin-conjugating enzymes in cancer: Implications for immunotherapeutic interventions.

Isobel S Okoye, J. Mohamadnejad, G. Azizi, 2019, Clinica chimica acta; international journal of clinical chemistry.

Tackling Immune Targets for Breast Cancer: Beyond PD-1/PD-L1 Axis

Isobel S Okoye, Y. Tabana, A. Siraki, 2021, Frontiers in Oncology.

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

Isobel S Okoye, T. Tolmachova, Stephanie Czieso, 2014, Immunity.

Targeting B7‐1 in immunotherapy

A. Ganesan, Isobel S Okoye, E. Arutyunova, 2020, Medicinal research reviews.

Expanded antigen-experienced CD160+CD8+effector T cells exhibit impaired effector functions in chronic lymphocytic leukemia

Lai Xu, Isobel S Okoye, S. Elahi, 2021, Journal for ImmunoTherapy of Cancer.

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

Isobel S Okoye, T. Tolmachova, Stephanie Czieso, 2014, Immunity.

Plasma Extracellular Vesicles Enhance HIV-1 Infection of Activated CD4+ T Cells and Promote the Activation of Latently Infected J-Lat10.6 Cells via miR-139-5p Transfer

Lai Xu, Isobel S Okoye, S. Elahi, 2021, Frontiers in Immunology.

Hypoxia inducible factors in the tumor microenvironment as therapeutic targets of cancer stem cells.

Isobel S Okoye, G. Azizi, Ghasem Ghalamfarsa, 2019, Life sciences.

IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells

Isobel S Okoye, J. Langhorne, Stephanie Czieso, 2015, PLoS pathogens.

Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer

Isobel S Okoye, S. Elahi, M. Houghton, 2017, Front. Immunol..

Elevated ATP via enhanced miRNA-30b, 30c, and 30e downregulates the expression of CD73 in CD8+ T cells of HIV-infected individuals

Isobel S Okoye, S. Elahi, G. Blevins, 2022, PLoS pathogens.

Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity

D. Baltimore, Isobel S Okoye, J. Langhorne, 2014, Proceedings of the National Academy of Sciences.

Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells

Isobel S Okoye, S. Ley, Stephanie Czieso, 2017, The Journal of allergy and clinical immunology.

miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Schistosome and Leishmania-associated Inflammation

P. Sethupathy, Y. Belkaid, Isobel S Okoye, 2013, PLoS pathogens.

T-cell–intrinsic Tif1α/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy

Isobel S Okoye, Stephanie Czieso, I. Davidson, 2016, Proceedings of the National Academy of Sciences.

The protein LEM promotes CD8+ T cell immunity through effects on mitochondrial respiration

A. Oxenius, Isobel S Okoye, R. Abdi, 2015, Science.

Atorvastatin downregulates co-inhibitory receptor expression by targeting Ras-activated mTOR signalling

Lai Xu, Isobel S Okoye, S. Elahi, 2017, Oncotarget.

Galectin-9 expression defines exhausted T cells and impaired cytotoxic NK cells in patients with virus-associated solid tumors

Lai Xu, Isobel S Okoye, John W Walker, 2020, Journal for ImmunoTherapy of Cancer.

The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade

Lai Xu, Isobel S Okoye, John W Walker, 2020, Cancer Immunology, Immunotherapy.

CD71+ erythroid cells suppress T-cell effector functions and predict immunotherapy outcomes in patients with virus-associated solid tumors

Isobel S Okoye, S. Elahi, P. Koleva, 2023, Journal for ImmunoTherapy of Cancer.