D. Chin

发表

Noncovalent Synthesis: Using Physical-Organic Chemistry To Make Aggregates

G. Whitesides, J. Mathias, C. Seto, 1995 .

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Thomas M. Smith, D. Curtis, B. Tseng, 2015, Nature chemical biology.

The Evaluation of Multi-Body Dynamics for Studying Ligand—Protein Interactions: Using MBO(N)D to Probe the Unbinding Pathways of Cbz-Val-Phe-Phe-Val-Cbz from the Active Site of HIV-1 Protease

Hon M. Chun, Carlos E. Padilla, H. M. Chun, 1999 .

Studying how different terminal groups change the motion of H2NSO2C6H4CONH(EG)3R when bound to the active site of human carbonic anhydrase II.

G. Whitesides, D. Chin, A. Lau, 1998, The Journal of organic chemistry.

Molecular Dynamics Simulations of H2NSO2C6H4CONH(Gly)3OBn Bound to the Active Site of Human Carbonic Anhydrase II

G. Whitesides, D. Chin, 1995 .

Engineering the Solid State with 2-Benzimidazolones

G. Whitesides, D. Chin, J. MacDonald, 1996 .

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Thomas M. Smith, John A. Tallarico, D. Curtis, 2015, Nature chemical biology.

Design and synthesis of a series of meta aniline-based LFA-1 ICAM inhibitors.

K. Guckian, D. Chin, L. Silvian, 2008, Bioorganic & medicinal chemistry letters.

Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA).

D. Curtis, M. Hild, Yiping Shen, 2018, Journal of medicinal chemistry.

Design and synthesis of hydrogen-bonded aggregates. Theory and computation applied to three systems based on the cyanuric acid-melamine lattice

George M. Whitesides, Eric E. Simanek, Donovan N. Chin, 1995 .

Structure-activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors.

H. V. van Vlijmen, K. Guckian, D. Chin, 2008, Bioorganic & medicinal chemistry letters.

Self-Assembling Systems on Scales from Nanometers to Millimeters: Design and Discovery

G. Whitesides, Younan Xia, N. Bowden, 2007 .

Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G‐quadruplex in K+ Buffer

D. Chin, Steven T. G. Street, M. Berry, 2017, Chemistry.

Hydrogen-Bonded Tapes Based on Symmetrically Substituted Diketopiperazines: A Robust Structural Motif for the Engineering of Molecular Solids

G. Whitesides, E. Simanek, D. Chin, 1997 .

A Kinase‐focused Compound Collection: Compilation and Screening Strategy

Jessica Friedman, Patrick Cullen, Jason Donnelly, 2006, Chemical biology & drug design.

MBO(N)D: A multibody method for long‐time molecular dynamics simulations

Carlos E. Padilla, Valeri I. Karlov, Barry L. Farmer, 2000 .

PEARL-seq: A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions.

Jenifer B. Kaplan, D. Chin, Lee E. Vandivier, 2020, ACS chemical biology.

Use of Intramolecular 1,5-Sulfur-Oxygen and 1,5-Sulfur-Halogen Interactions in the Design of N-Methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators.

D. Chin, L. Hamann, K. Briner, 2021, Journal of medicinal chemistry.

Identification of NVP-TNKS656: the use of structure-efficiency relationships to generate a highly potent, selective, and orally active tankyrase inhibitor.

D. Chin, B. Lagu, B. Firestone, 2013, Journal of medicinal chemistry.

Synthesis of ciprofloxacin dimers for evaluation of bacterial permeability in atypical chemical space.

D. Chin, J. Leeds, M. LaMarche, 2015, Bioorganic & medicinal chemistry letters.

STUDIES IN THE ORGANIC SOLID STATE

G. Whitesides, D. Chin, J. MacDonald, 1993 .

[1,2,4]triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: antagonists of the Wnt pathway that inhibit tankyrases 1 and 2 via novel adenosine pocket binding.

D. Chin, W. Shao, Yun Feng, 2012, Journal of medicinal chemistry.

Integration of virtual screening into the drug discovery process.

D N Chin, C E Chuaqui, J Singh, 2004, Mini reviews in medicinal chemistry.

Structure-efficiency relationship of [1,2,4]triazol-3-ylamines as novel nicotinamide isosteres that inhibit tankyrases.

D. Chin, W. Shao, Yun Feng, 2013, Journal of medicinal chemistry.

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Thomas M. Smith, John A. Tallarico, D. Curtis, 2015, Nature chemical biology.

Computational Simulations of Supramolecular Hydrogen-Bonded Aggregates: HubM3, FlexM3, and Adamantane-Based Hubs in Chloroform

G. Whitesides, D. Chin, D. M. Gordon, 1994 .

Synthesis and Evaluation of Thioether-Based Tris-Melamines as Components of Self-Assembled Aggregates Based on the CA.M Lattice.

G. Whitesides, D. Chin, Xinhua Li, 1996, The Journal of organic chemistry.

FOCUS - Development of a Global Communication and Modeling Platform for Applied and Computational Medicinal Chemists

Peter Gedeck, Ruben Abagyan, Maxim Totrov, 2015, J. Chem. Inf. Model..

A Simple Solvation Model Along with A Multibody Dynamics Strategy (MBO(N)D) Produces Stable DNA Simulations that are Faster than Traditional Atomistic Methods

H. M. Chun, T. Schlick, F. Sussman, 2000 .