R. Center

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Complexity of the Inoculum Determines the Rate of Reversion of SIV Gag CD8 T Cell Mutant Virus and Outcome of Infection

L. Loh, J. Reece, C. Fernandez, 2009, PLoS pathogens.

Crystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins.

R. Center, B. Kemp, B. Kobe, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Track A Basic Science

S. Sugden, D. Hazuda, F. Pereyra, 2012, Journal of the International AIDS Society.

Identification of brain isoforms of the rat calcitonin receptor.

P. Sexton, R. Center, P. Darcy, 1993, Molecular endocrinology.

Trimeric gp120-specific bovine monoclonal antibodies require cysteine and aromatic residues in CDRH3 for high affinity binding to HIV Env

R. Center, D. Purcell, G. Khoury, 2016, mAbs.

Inhibition of Two Temporal Phases of HIV-1 Transfer from Primary Langerhans Cells to T Cells: The Role of Langerin

R. Center, P. Gorry, N. Nasr, 2014, The Journal of Immunology.

Enhancing the antigenicity and immunogenicity of monomeric forms of hepatitis C virus E2 for use as a preventive vaccine

R. Center, H. Drummer, P. Poumbourios, 2020, The Journal of Biological Chemistry.

Hyperimmune Bovine Colostrum as a Low-Cost, Large-Scale Source of Antibodies with Broad Neutralizing Activity for HIV-1 Envelope with Potential Use in Microbicides

R. Center, D. Purcell, A. Wheatley, 2012, Antimicrobial Agents and Chemotherapy.

Immunogenicity of HIV-1-Based Virus-Like Particles with Increased Incorporation and Stability of Membrane-Bound Env

R. Center, D. Purcell, C. Gonelli, 2021, Vaccines.

Disulfide Bond That Constrains the HIV-1 gp120 V3 Domain Is Cleaved by Thioredoxin*

J. W. Wong, R. Center, I. Azimi, 2010, The Journal of Biological Chemistry.

Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites

G. McFadden, R. Center, J. Kazura, 2021, Nature Communications.

The core domain of hepatitis C virus glycoprotein E2 generates potent cross‐neutralizing antibodies in guinea pigs

R. Center, L. Fabri, M. Hardy, 2017, Hepatology.

HIV-1 Env- and Vpu-Specific Antibody-Dependent Cellular Cytotoxicity Responses Associated with Elite Control of HIV

R. Center, S. Kent, A. Kelleher, 2017, Journal of Virology.

Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to ‘protective’ human leukocyte antigen-B alleles in HIV controllers

R. Center, S. Kent, A. Kelleher, 2013, AIDS.

Balancing Reversion of Cytotoxic T-Lymphocyte and Neutralizing Antibody Escape Mutations within Human Immunodeficiency Virus Type 1 Env upon Transmission

C. Fernandez, S. Alcântara, R. Center, 2009, Journal of Virology.

Rapid Degranulation of NK Cells following Activation by HIV-Specific Antibodies1

R. Center, S. Kent, E. Rollman, 2009, The Journal of Immunology.

Induction of HIV-1 subtype B and AE-specific neutralizing antibodies in mice and macaques with DNA prime and recombinant gp140 protein boost regimens.

S. Alcântara, R. Center, D. Purcell, 2009, Vaccine.

Sindbis virus vectors elicit hemagglutinin-specific humoral and cellular immune responses and offer a dose-sparing strategy for vaccination.

R. Center, J. Howard, D. Purcell, 2008, Vaccine.

Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection

D. Montefiori, J. Lifson, R. Center, 2017, Science Translational Medicine.

Role of education and differentiation in determining the potential of natural killer cells to respond to antibody-dependent stimulation

L. Loh, R. Center, S. Kent, 2014, AIDS.

A pan‐genotype hepatitis C virus viral vector vaccine generates T cells and neutralizing antibodies in mice

P. Klenerman, R. Center, E. Barnes, 2022, Hepatology.

Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core

R. Center, S. Turville, H. Drummer, 2022, bioRxiv.

Antibody-dependent effector functions against HIV decline in subjects receiving antiretroviral therapy.

J. Ananworanich, D. Cooper, R. Center, 2015, The Journal of infectious diseases.

HIV-1-Based Virus-like Particles that Morphologically Resemble Mature, Infectious HIV-1 Virions

R. Center, D. Purcell, G. Khoury, 2019, Viruses.

Co-Expression of miRNA Targeting the Expression of PERK, but Not PKR, Enhances Cellular Immunity from an HIV-1 Env DNA Vaccine

R. Center, D. Purcell, A. Wheatley, 2011, PloS one.

Efficient transcription through an intron requires the binding of an Sm-type U1 snRNP with intact stem loop II to the splice donor

R. Center, D. Purcell, A. Wheatley, 2010, Nucleic acids research.

Differentiating founder and chronic HIV envelope sequences

R. Center, D. Purcell, A. Kelleher, 2017, PloS one.

Human immunodeficiency virus type 1 envelope glycoprotein oligomerization requires the gp41 amphipathic alpha-helical/leucine zipper-like sequence

R. Center, B. Kemp, P. Poumbourios, 1997, Journal of virology.

Application of a case–control study design to investigate genotypic signatures of HIV-1 transmission

J. McCaw, R. Center, D. Purcell, 2012, Retrovirology.

Virus-Like Particles Containing the E2 Core Domain of Hepatitis C Virus Generate Broadly Neutralizing Antibodies in Guinea Pigs

R. Center, M. Piontek, M. Suckow, 2022, Journal of virology.

Influence of Cytokines on HIV-Specific Antibody-Dependent Cellular Cytotoxicity Activation Profile of Natural Killer Cells

R. Center, S. Kent, A. Kelleher, 2012, PloS one.

The maturation of antibody technology for the HIV epidemic

R. Center, S. Kent, M. Parsons, 2014, Immunology and cell biology.

Short communication: antibody responses to human immunodeficiency virus envelope from infections with multiple subtypes utilize the 1F7-idiotypic repertoire.

M. Wainberg, C. Tremblay, R. Center, 2013, AIDS research and human retroviruses.

Immune escape from HIV-specific antibody-dependent cellular cytotoxicity (ADCC) pressure

R. Center, S. Kent, M. Navis, 2011, Proceedings of the National Academy of Sciences.

NK cell function and antibodies mediating ADCC in HIV-1-infected viremic and controller patients.

R. Center, S. Kent, B. Wahrén, 2011, Viral immunology.

Functional advantage of educated KIR2DL1+ natural killer cells for anti‐HIV‐1 antibody‐dependent activation

R. Center, S. Kent, M. Parsons, 2016, Clinical and experimental immunology.

Anti-HIV Antibody–Dependent Activation of NK Cells Impairs NKp46 Expression

R. Center, S. Kent, M. Parsons, 2014, The Journal of Immunology.

Brief Report: Seminal Plasma Anti-HIV Antibodies Trigger Antibody-dependent Cellular Cytotoxicity Implications for HIV Transmission

K. Ruxrungtham, R. Center, S. Kent, 2016, Journal of acquired immune deficiency syndromes.

Breadth of HIV-1 Env-specific antibody-dependent cellular cytotoxicity: relevance to global HIV vaccine design

R. Center, S. Kent, C. Gonelli, 2014, AIDS.

Role of monocytes in mediating HIV-specific antibody-dependent cellular cytotoxicity.

R. Center, S. Kent, A. Kelleher, 2012, Journal of immunological methods.

Anti‐HIV‐1 antibody‐dependent cellular cytotoxicity mediated by hyperimmune bovine colostrum IgG

R. Center, D. Purcell, S. Kent, 2012, European journal of immunology.

Identification of Native and Posttranslationally Modified HLA‐B*57:01‐Restricted HIV Envelope Derived Epitopes Using Immunoproteomics

Sri H. Ramarathinam, S. Alcântara, R. Center, 2018, Proteomics.

A point-of-care lateral flow assay for neutralising antibodies against SARS-CoV-2

R. Center, D. Purcell, K. Subbarao, 2021, EBioMedicine.

Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles

R. Center, D. Purcell, F. Pedersen, 2011, Virology Journal.

Crystallization of a trimeric human T cell leukemia virus type 1 gp21 ectodomain fragment as a chimera with maltose‐binding protein

R. Center, B. Kemp, B. Kobe, 1998, Protein science : a publication of the Protein Society.

Human immunodeficiency virus type 1 and 2 envelope glycoproteins oligomerize through conserved sequences

R. Center, B. Kemp, P. Poumbourios, 1997, Journal of virology.

HIV‐specific antibody‐dependent phagocytosis matures during HIV infection

Jerome H. Kim, R. Center, S. Kent, 2014, Immunology and cell biology.

Conjugation of an scFab domain to the oligomeric HIV envelope protein for use in immune targeting

R. Center, D. Purcell, C. Gonelli, 2019, PloS one.

Functional Implications of the Human T-Lymphotropic Virus Type 1 Transmembrane Glycoprotein Helical Hairpin Structure

R. Center, B. Kemp, B. Kobe, 2000, Journal of Virology.

Utility of the Sindbis replicon system as an Env-targeted HIV vaccine.

R. Center, D. Purcell, A. Wheatley, 2013, Vaccine.

Oligomeric Structure of the Human Immunodeficiency Virus Type 1 Envelope Protein on the Virion Surface

Richard D. Leapman, P. Earl, B. Moss, 2002, Journal of Virology.

Oligomeric structure of virion-associated and soluble forms of the simian immunodeficiency virus envelope protein in the prefusion activated conformation

P. Earl, B. Moss, R. Leapman, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Promoting Trimerization of Soluble Human Immunodeficiency Virus Type 1 (HIV-1) Env through the Use of HIV-1/Simian Immunodeficiency Virus Chimeras

B. Moss, R. Leapman, R. Center, 2004, Journal of Virology.

The Human Immunodeficiency Virus Type 1 gp120 V2 Domain Mediates gp41-Independent Intersubunit Contacts

P. Earl, B. Moss, R. Center, 2000, Journal of Virology.

Repeated Vaccination of Cows with HIV Env gp140 during Subsequent Pregnancies Elicits and Sustains an Enduring Strong Env-Binding and Neutralising Antibody Response

R. Center, D. Purcell, G. Khoury, 2016, PloS one.