A. Rufer

发表

Structure and Function of Purified Monoclonal Antibody Dimers Induced by Different Stress Conditions

R. Paul, A. Graff-Meyer, H. Stahlberg, 2012, Pharmaceutical Research.

Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones.

D. Banner, A. Kuglstatter, J. Steyaert, 2013, Acta crystallographica. Section D, Biological crystallography.

Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain

M. Rudolph, A. Rufer, S. Huber, 2020, The Journal of Biological Chemistry.

Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose

Armin Ruf, Jörg Benz, A. Rufer, 2011, Proceedings of the National Academy of Sciences.

A Novel Selective Inverse Agonist of the CB2 Receptor as a Radiolabeled Tool Compound for Kinetic Binding Studies

A. IJzerman, L. Heitman, T. Hartung, 2017, Molecular Pharmacology.

Structural insight into function and regulation of carnitine palmitoyltransferase

A. Rufer, M. Hennig, R. Thoma, 2009, Cellular and Molecular Life Sciences.

Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.

W. Guba, E. Carreira, A. Rufer, 2020, Journal of the American Chemical Society.

Cathepsin S inhibition combines control of systemic and peripheral pathomechanisms of autoimmune tissue injury

W. Haap, A. Rufer, H. Anders, 2017, Scientific Reports.

Structural Properties of AMP-activated Protein Kinase

A. Rufer, D. Svergun, S. Müller, 2008, Journal of Biological Chemistry.

Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP.

G. Dernick, A. Graff-Meyer, H. Stahlberg, 2016, Journal of structural biology.

X-ray structure of glutathione S-transferase from Schistosoma japonicum in a new crystal form reveals flexibility of the substrate-binding site.

A. Rufer, M. Hennig, H. Klein, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain

D. Banner, A. Rufer, M. Hennig, 2012, mAbs.

Biophysical Assessment of Target Protein Quality in Structure‐Based Drug Discovery

A. Rufer, M. Hennig, 2020 .

Carnitine palmitoyltransferase 2: Analysis of membrane association and complex structure with a substrate analog

A. Rufer, M. Hennig, R. Thoma, 2007, FEBS letters.

A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro

Armin Ruf, Hans Peter Märki, Jörg Benz, 2006 .

Isothermal titration calorimetry with micelles: Thermodynamics of inhibitor binding to carnitine palmitoyltransferase 2 membrane protein☆

S. Ceccarelli, T. Schulz-Gasch, A. Rufer, 2013, FEBS open bio.

Insulin receptor, AMPK and CPT-2: Crystallization experiments and structural characterization of three proteins relevant to diabetes mellitus

A. Rufer, 2006 .

Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance.

A. Rufer, M. Hennig, R. Dawson, 2015, Biochimica et biophysica acta.

A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation

P. V. von Hippel, P. Prevelige, R. Fairman, 2015, PloS one.

The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment.

Jörg Benz, D. Banner, A. Rufer, 2006, Structure.

Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody

M. Rudolph, A. Rufer, B. Gsell, 2016, eLife.

Diverse chemotypes drive biased signaling by cannabinoid receptors

W. Guba, A. Rufer, D. Veprintsev, 2020, bioRxiv.

Drug discovery for enzymes.

A. Rufer, 2021, Drug discovery today.

Domain swap in the C-terminal ubiquitin-like domain of human doublecortin.

M. Rudolph, A. Rufer, A. Ruf, 2018, Acta crystallographica. Section D, Structural biology.

Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies*

M. Steinmetz, M. Rudolph, J. Steyaert, 2016, The Journal of Biological Chemistry.

Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct

R. Jagasia, A. Rufer, V. Taylor, 2023, Nature Communications.

A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.

Armin Ruf, Hans Peter Märki, Jörg Benz, 2006, Molecular endocrinology.

Dimerization-induced activation of soluble insulin/IGF-1 receptor kinases: an alternative mechanism of activation.

A. Rufer, H. Klein, H. al-Hasani, 2001, Biochemistry.

Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport

W. Guba, A. Kuglstatter, A. Rufer, 2017, EBioMedicine.

Reply to Alarcon and Borroto: Small molecule AX-024 reduces T cell proliferation independently of CD3ε-Nck1 interaction at SH3.1

M. Rudolph, A. Rufer, S. Huber, 2020, The Journal of Biological Chemistry.

Structural and Functional Characterization of Doublecortin Domains 1 Crystal Structures of the Human Doublecortin Cand N-terminal Domains in Complex with Specific Antibodies

M. Steinmetz, M. Rudolph, A. Rufer, 2016 .

Isoform-selective interaction of the adaptor protein Tks5/FISH with Sos1 and dynamins.

A. Rufer, K. Rittinger, Y. Groemping, 2009, Journal of molecular biology.

Structure and Function of Purified Monoclonal Antibody Dimers Induced by Different Stress Conditions

R. Paul, A. Graff-Meyer, H. Stahlberg, 2012, Pharmaceutical Research.

Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe

H. Spaink, W. Guba, E. Carreira, 2022, Chemical science.

Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs

A. Graff-Meyer, H. Stahlberg, M. Lauer, 2016, mAbs.

Cathepsin S inhibition combines control of systemic and peripheral pathomechanisms of autoimmune tissue injury

W. Haap, A. Rufer, S. R. Mulay, 2017, Scientific Reports.

Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors

W. Guba, A. Rufer, D. Veprintsev, 2023, Frontiers in pharmacology.

Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody

M. Rudolph, A. Rufer, B. Gsell, 2017, eLife.

Carnitine palmitoyltransferase 2: Analysis of membrane association and complex structure with a substrate analog

A. Rufer, M. Hennig, R. Thoma, 2007, FEBS letters.

A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor- (cid:1) (PPAR (cid:1) ) Recruits PPAR (cid:1) -Coactivator-1 (cid:2) , Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro

B. Kuhn, A. Rufer, B. Gsell, 2006 .