I. Vetter

发表

A Bayesian model predicts the response of axons to molecular gradients

P. Dayan, K. Burrage, G. Goodhill, 2009, Proceedings of the National Academy of Sciences.

G. Goodhill, D. Mortimer, Z. Pujic, 2010, Proceedings of the National Academy of Sciences.

Convergent evolution of pain-inducing defensive venom components in spitting cobras

P. Dorrestein, J. Calvete, I. Vetter, 2020, Science.

Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target

I. Vetter, R. Lewis, Kathleen Yin, 2016, Molecular pain.

Analgesic treatment of ciguatoxin-induced cold allodynia

I. Vetter, R. Lewis, B. Namer, 2013, PAIN®.

Rapid Extraction and Identification of Maitotoxin and Ciguatoxin-Like Toxins from Caribbean and Pacific Gambierdiscus Using a New Functional Bioassay

I. Vetter, R. Lewis, R. Litaker, 2016, PloS one.

Ciguatoxin and Ciguatera

I. Vetter, R. Lewis, 2016 .

Ciguatoxin Detection Methods and High‐Throughput Assays

I. Vetter, R. Lewis, Alun Jones, 2017 .

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

K. Schroder, D. Kastner, I. Vetter, 2015, Nature Medicine.

The pharmacology of voltage-gated sodium channel activators

Irina Vetter, I. Vetter, J. Deuis, 2017, Neuropharmacology.

Voltage‐Gated Sodium Channels as Therapeutic Targets

I. Vetter, R. Lewis, Joshua S. Wingerd, 2012 .

Differential Evolution and Neofunctionalization of Snake Venom Metalloprotease Domains*

I. Vetter, A. Antunes, R. Lewis, 2012, Molecular & Cellular Proteomics.

Comparative evolution of Psammophis and Echis snake venom metalloproteases (svmp)

I. Vetter, A. Antunes, R. Lewis, 2012 .

High-Throughput Fluorescence Assays for Ion Channels and GPCRs.

I. Vetter, S. Robinson, D. Carter, 2020, Advances in experimental medicine and biology.

Toxicology of ciguatoxins

I. Vetter, R. Lewis, 2014 .

Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider

Stewart Heitmann, I. Vetter, David John Adams, 2022, Proceedings of the National Academy of Sciences.

The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes

I. Vetter, K. Mardon, S. Kuruppu, 2017, Current Biology.

NaV1.1 and NaV1.6 selective compounds reduce the behavior phenotype in a novel zebrafish model for Dravet Syndrome

I. Vetter, B. Koeleman, K. Braun, 2019, bioRxiv.

Characterisation of Na(v) types endogenously expressed in human SH-SY5Y neuroblastoma cells.

I. Vetter, T. Durek, R. Lewis, 2012, Biochemical pharmacology.

Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1

I. Vetter, R. Lewis, A. Keramidas, 2017, Scientific Reports.

Characterisation of a Novel A-Superfamily Conotoxin

I. Vetter, A. Nicke, N. Daly, 2020, Biomedicines.

Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy

I. Vetter, H. Starobova, Hana Starobova, 2017, Front. Mol. Neurosci..

An Integrated Proteomic and Transcriptomic Analysis Reveals the Venom Complexity of the Bullet Ant Paraponera clavata

Mrinalini, Regan J. Hayward, G. Myers, 2020, Toxins.

The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site

R. Papke, J. Meiler, I. Vetter, 2021, Toxins.

Vps26B‐retromer negatively regulates plasma membrane resensitization of PAR‐2

R. Teasdale, I. Vetter, B. Collins, 2015, Cell biology international.

Role of complement anaphylatoxin receptors in a mouse model of acute burn‐induced pain

I. Vetter, T. Woodruff, R. Lewis, 2018, Molecular immunology.

Optimization and In Vivo Profiling of a Refined Rat Model of Walker 256 Breast Cancer Cell-Induced Bone Pain Using Behavioral, Radiological, Histological, Immunohistochemical and Pharmacological Methods

I. Vetter, Maree T. Smith, A. Kuo, 2017, Front. Pharmacol..

Transcriptomics in pain research: insights from new and old technologies.

I. Vetter, H. Starobova, R. Lewis, 2018, Molecular omics.

The zebrafish grime mutant uncovers an evolutionarily conserved role for Tmem161b in the control of cardiac rhythm

S. Petrou, I. Vetter, C. Simons, 2021, Proceedings of the National Academy of Sciences.

A new selective pharmacological enhancer of the Orai1 Ca2+ channel reveals roles for Orai1 in smooth and skeletal muscle functions.

W. Denny, I. Vetter, I. Azimi, 2020, ACS pharmacology & translational science.

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors.

I. Vetter, M. Cooper, David John Adams, 2015, Journal of the American Chemical Society.

Subcutaneous ω-Conotoxins Alleviate Mechanical Pain in Rodent Models of Acute Peripheral Neuropathy

I. Vetter, R. Lewis, A. Mueller, 2021, Marine drugs.

Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox

D. Craik, I. Vetter, P. Harvey, 2022, The Journal of biological chemistry.

Polygodial, a drimane sesquiterpenoid dialdehyde purified from Drimys winteri, inhibits voltage-gated sodium channels.

I. Vetter, J. Deuis, Cristian Paz, 2022, Natural product research.

Therapeutic potential of cone snail venom peptides (conopeptides).

I. Vetter, R. Lewis, 2012, Current topics in medicinal chemistry.

Novel Neurotoxic Activity in Calliophis intestinalis Venom

I. Vetter, B. Fry, A. Nouwens, 2021, Neurotoxicity Research.

A small molecule inhibitior of the NLRP 3 inflammasome is a potential therapeutic for inflammatory diseases

K. Schroder, D. Kastner, I. Vetter, 2015 .

Modulation of TRPV1-mediated capsaicin responses potentiated through PKC and camp-dependent PKA pathways by the Mu opioid receptor agonist morphine

I. Vetter, P. Cabot, G. Monteith, 2006 .

Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system

Yuehua Wu, D. Craik, I. Vetter, 2022, Nature communications.

Synthesis of Multivalent [Lys8]-Oxytocin Dendrimers that Inhibit Visceral Nociceptive Responses

M. Nilsson, I. Vetter, M. Cooper, 2017 .

Differential Evolution and Neofunctionalization of Snake Venom Metalloprotease Domains

I. Vetter, A. Antunes, R. Lewis, 2012, Molecular & Cellular Proteomics.

Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels.

I. Vetter, David John Adams, R. Lewis, 2012, Biochemical pharmacology.

It Takes Two: Dimerization Is Essential for the Broad-Spectrum Predatory and Defensive Activities of the Venom Peptide Mp1a from the Jack Jumper Ant Myrmecia pilosula

I. Vetter, Shaodong Guo, G. King, 2020, Biomedicines.

Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a

Glenn F. King, Paul F. Alewood, Sulayman D. Dib-Hajj, 2017, Scientific Reports.

The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation

I. Vetter, G. King, S. Robinson, 2022, Frontiers in Pharmacology.

Characterization of Synthetic Tf2 as a NaV1.3 Selective Pharmacological Probe

D. Craik, I. Vetter, T. Durek, 2020, Biomedicines.

Addition of K22 Converts Spider Venom Peptide Pme2a from an Activator to an Inhibitor of NaV1.7

I. Vetter, G. King, P. Alewood, 2020, Biomedicines.

The thermal probe test: A novel behavioral assay to quantify thermal paw withdrawal thresholds in mice

I. Vetter, J. Deuis, 2016, Temperature.

Activation of κ Opioid Receptors in Cutaneous Nerve Endings by Conorphin-1, a Novel Subtype-Selective Conopeptide, Does Not Mediate Peripheral Analgesia.

I. Vetter, R. Lewis, P. Cabot, 2015, ACS chemical neuroscience.

Characterization of endogenous calcium responses in neuronal cell lines.

I. Vetter, R. Lewis, 2010, Biochemical pharmacology.

Pharmacology and Therapeutic Potential of Venom Peptides.

I. Vetter, S. Robinson, 2020, Biochemical pharmacology.

MrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptors.

I. Vetter, R. Lewis, P. Alewood, 2014, Biochemistry.

Australian funnel-web spiders evolved human-lethal δ-hexatoxins for defense against vertebrate predators

I. Vetter, R. Lewis, G. King, 2020, Proceedings of the National Academy of Sciences.

Venomics: a new paradigm for natural products-based drug discovery

Mehdi Mobli, Glenn F. King, Paul F. Alewood, 2010, Amino Acids.

Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels.

I. Vetter, R. Lewis, P. Alewood, 2019, Biochemical pharmacology.

Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target NaV1.7.

I. Vetter, R. Lewis, G. King, 2020, Biochemical pharmacology.

Modulatory features of the novel spider toxin μ-TRTX-Df 1 a isolated from the venom of the spider Davus fasciatus . Running title : Modulation of voltage-gated channels by the spider toxin Df 1 a

I. Vetter, Jennifer J. Smith, R. Lewis, 2017 .

Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a

D. A. Armstrong, S. Dib-Hajj, S. Waxman, 2017, Scientific Reports.

Role of the NLRP3 inflammasome in a model of acute burn-induced pain.

K. Schroder, I. Vetter, M. Cooper, 2017, Burns : journal of the International Society for Burn Injuries.

Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling

I. Vetter, A. Hess, R. Lewis, 2012, The EMBO journal.

Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation.

I. Vetter, T. Durek, D. Carter, 2022, European journal of pharmacology.

µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype NaV1.7

D. Craik, I. Vetter, C. Schroeder, 2022, Toxins.

The voltage-gated sodium channel NaV1.7 underlies endometriosis-associated chronic pelvic pain

I. Vetter, G. King, S. Brierley, 2022, bioRxiv.

Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target Na V 1.8

D. Craik, I. Vetter, S. Henriques, 2016 .

Chemotherapy-induced peripheral neuropathy in children and adolescent cancer patients

I. Vetter, R. Endersby, E. Laakso, 2022, Frontiers in Molecular Biosciences.

Structural and functional insights into the inhibition of human voltage-gated sodium channels by μ -conotoxin KIIIA disul ﬁ de isomers

I. Vetter, C. Schroeder, J. Deuis, 2022 .

Development of a high-throughput fluorescent no-wash sodium influx assay

I. Vetter, J. Deuis, F. Davis, 2019, PloS one.

Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release

K. Schroder, I. Vetter, J. Lévesque, 2021, The Journal of experimental medicine.

Venom-derived pain-causing toxins: insights into sensory neuron function and pain mechanisms.

I. Vetter, Vanessa Schendel, S. Robinson, 2022, Pain.

2-nitroveratryl as a photocleavable thiol-protecting group for directed disulfide bond formation in the chemical synthesis of insulin.

I. Vetter, J. Wade, R. Lewis, 2014, Chemistry.

Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities.

I. Vetter, M. Aguilar, M. Cooper, 2017, Angewandte Chemie.

Development of a (cid:2) O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel Na V 1.8 *

D. Craik, I. Vetter, C. Schroeder, 2020 .

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling

D. Hume, B. McColl, I. Vetter, 2022, Development.

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant-negative impact on CSF1R signaling

D. Hume, B. McColl, I. Vetter, 2021, bioRxiv.

Pharmacological characterization of α-elapitoxin-Al2a from the venom of the Australian pygmy copperhead (Austrelaps labialis): an atypical long-chain α-neurotoxin with only weak affinity for α7 nicotinic receptors.

I. Vetter, R. Lewis, F. Marcon, 2012, Biochemical pharmacology.

Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus.

I. Vetter, R. Lewis, P. Alewood, 2015, Journal of proteome research.

Design, Synthesis and Biological Evaluation of Two Opioid Agonist and Cav2.2 Blocker Multitarget Ligands

E. Novellino, A. Mollica, I. Vetter, 2015, Chemical biology & drug design.

Anti-seizure mechanisms of midazolam and valproate at the β2(L51M) variant of the GABAA receptor

I. Vetter, A. Keramidas, E. Palmer, 2022, Neuropharmacology.

Intra-colony venom diversity contributes to maintaining eusociality in a cooperatively breeding ant

I. Vetter, C. Schroeder, Vanessa Schendel, 2023, BMC Biology.

Venom composition and pain-causing toxins of the Australian great carpenter bee Xylocopa aruana

I. Vetter, C. Schroeder, S. Robinson, 2022, Scientific reports.

Endogenous opioid analgesia in peripheral tissues and the clinical implications for pain control

I. Vetter, P. Cabot, Daniel Kapitzke, 2005, Therapeutics and clinical risk management.

Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain

Paul F. Alewood, Irina Vetter, Katharina Zimmermann, 2016, Toxins.

α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure.

D. Craik, I. Vetter, R. Lewis, 2011, Journal of the American Chemical Society.

Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay.

W. Denny, I. Vetter, I. Azimi, 2017, Bioorganic & medicinal chemistry.

Inhibition of N-Type Calcium Channels by Fluorophenoxyanilide Derivatives

I. Vetter, R. Lewis, K. Tuck, 2015, Marine drugs.

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

I. Vetter, R. Lewis, G. King, 2014, Nature Communications.

Development and optimization of FLIPR high throughput calcium assays for ion channels and GPCRs.

I. Vetter, 2012, Advances in experimental medicine and biology.

Mechanisms involved in potentiation of transient receptor potential vanilloid 1 responses by ethanol

I. Vetter, P. Cabot, G. Monteith, 2008, European journal of pain.

Toxins in Neurobiology: New tools from old molecules

I. Vetter, 2017, Neuroscience Letters.

The Snake with the Scorpion’s Sting: Novel Three-Finger Toxin Sodium Channel Activators from the Venom of the Long-Glanded Blue Coral Snake (Calliophis bivirgatus)

I. Vetter, T. Bruxner, B. Fry, 2016, Toxins.

(-)-Pentylsedinine, a New Alkaloid from the Leaves of Lobelia Tupa with Agonist Activity at Nicotinic Acetylcholine Receptor

I. Vetter, M. Heydenreich, J. Becerra, 2015, Natural product communications.

Missiles of Mass Disruption: Composition and Glandular Origin of Venom Used as a Projectile Defensive Weapon by the Assassin Bug Platymeris rhadamanthus

I. Vetter, G. King, S. Robinson, 2019, Toxins.

Inflammatory and neuropathic gene expression signatures of chemotherapy-induced neuropathy induced by vincristine, cisplatin and oxaliplatin in C57BL/6J mice.

I. Vetter, D. Carter, J. Deuis, 2019, The journal of pain : official journal of the American Pain Society.

Natural product ligands of TRP channels.

I. Vetter, R. Lewis, 2011, Advances in experimental medicine and biology.

The NLRP3 Inflammasome: Role and Therapeutic Potential in Pain Treatment

I. Vetter, H. Starobova, E. Nadar, 2020, Frontiers in Physiology.

Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans

I. Vetter, C. Schroeder, D. Merritt, 2021, Proceedings of the National Academy of Sciences.

Rapid, Opioid-sensitive Mechanisms Involved in Transient Receptor Potential Vanilloid 1 Sensitization*

I. Vetter, Jie Zheng, P. Cabot, 2008, Journal of Biological Chemistry.

The μ opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway

I. Vetter, P. Cabot, G. Monteith, 2006, Molecular pain.

Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7

D. Craik, I. Vetter, C. Schroeder, 2020, The Journal of Biological Chemistry.

Sodium Channels and Venom Peptide Pharmacology.

I. Vetter, J. Deuis, Mathilde R. Israel, 2017, Advances in pharmacology.

Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell‐induced bone pain

I. Vetter, G. Leparc, T. Hildebrandt, 2019, Clinical and experimental pharmacology & physiology.

The Walker 256 Breast Cancer Cell- Induced Bone Pain Model in Rats

I. Vetter, Maree T. Smith, A. Kuo, 2016, Front. Pharmacol..

Methods Used to Evaluate Pain Behaviors in Rodents

Irina Vetter, I. Vetter, L. Dvorakova, 2017, Front. Mol. Neurosci..

Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails

I. Vetter, A. Antunes, R. Lewis, 2014, Nature Communications.

The Somatostatin Receptor-4 Agonist J-2156 Alleviates Mechanical Hypersensitivity in a Rat Model of Breast Cancer Induced Bone Pain

I. Vetter, Maree T. Smith, L. Corradini, 2018, Front. Pharmacol..

Burn Pain: A Systematic and Critical Review of Epidemiology, Pathophysiology, and Treatment

I. Vetter, R. Lewis, P. Cabot, 2018, Pain medicine.

NaV1.7 as a pain target - From gene to pharmacology.

I. Vetter, M. Mobli, J. Deuis, 2017, Pharmacology & therapeutics.

Ciguatera fish poisoning: a first epidemic in Germany highlights an increasing risk for European countries.

I. Vetter, B. Krock, K. Zimmermann, 2014, Toxicon : official journal of the International Society on Toxinology.

Release of neuropeptides from a neuro-cutaneous co-culture model: A novel in vitro model for studying sensory effects of ciguatoxins.

I. Vetter, L. Misery, R. Lewis, 2016, Toxicon : official journal of the International Society on Toxinology.

Poisoning by Tropical Fish: Ciguatera-Epidemic in Germany

I. Vetter, K. Zimmermann, H. Desel, 2015 .

Therapeutic opportunities for targeting cold pain pathways.

I. Vetter, R. Lewis, Kathleen Yin, 2015, Biochemical pharmacology.

A ray of venom: Combined proteomic and transcriptomic investigation of fish venom composition using barb tissue from the blue-spotted stingray (Neotrygon kuhlii).

I. Vetter, S. A. Ali, N. Casewell, 2014, Journal of proteomics.

A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa, reveals a hyperdiverse hymenopteran toxin gene family

I. Vetter, R. Payne, G. King, 2018, Science Advances.

Animal toxins — Nature’s evolutionary-refined toolkit for basic research and drug discovery

I. Vetter, G. King, V. Herzig, 2020, Biochemical Pharmacology.

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways

A. A. Romanovsky, I. Vetter, R. Lewis, 2013, PAIN®.

The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states

J. Mattick, L. Lipovich, G. Franco, 2017, Scientific Reports.

Pharmacological screening technologies for venom peptide discovery

Irina Vetter, I. Vetter, Jutty Rajan Prashanth, 2017, Neuropharmacology.

A pain-causing and paralytic ant venom glycopeptide

I. Vetter, R. Payne, A. Keramidas, 2021, iScience.

Small cyclic sodium channel inhibitors.

D. Craik, I. Vetter, J. Tytgat, 2020, Biochemical pharmacology.

Buzz Kill: Function and Proteomic Composition of Venom from the Giant Assassin Fly Dolopus genitalis (Diptera: Asilidae)

I. Vetter, G. King, S. Robinson, 2018, Toxins.

Enzymatic ligation of a pore blocker toxin and gating modifier toxin; creating double-knotted peptides with improved sodium channel NaV1.7 inhibition.

I. Vetter, C. Schroeder, J. Deuis, 2019, Bioconjugate chemistry.

Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7*

A. Mark, D. Craik, I. Vetter, 2016, The Journal of Biological Chemistry.

Engineering of a Spider Peptide via Conserved Structure-Function Traits Optimizes Sodium Channel Inhibition In Vitro and Anti-Nociception In Vivo

I. Vetter, J. Deuis, F. C. Cardoso, 2021, Frontiers in Molecular Biosciences.

NaV1.6 regulates excitability of mechanosensitive sensory neurons

S. Dib-Hajj, S. Waxman, D. Craik, 2019, The Journal of physiology.

Structural and functional insights into the inhibition of human voltage-gated sodium channels by μ-conotoxin KIIIA disulfide isomers

I. Vetter, C. Schroeder, J. Deuis, 2022, The Journal of biological chemistry.

Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible NaV Channel Inhibitor

I. Vetter, C. Schroeder, R. Lewis, 2020, Biomedicines.

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species

Terry J. Smith, S. Wray, I. Vetter, 2017, Science Signaling.

Conus Venom Peptide Pharmacology

I. Vetter, R. Lewis, S. Dutertre, 2012, Pharmacological Reviews.

A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins.

D. Craik, I. Vetter, J. Tytgat, 2019, Structure.

Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracica

I. Vetter, G. King, V. Herzig, 2016, PloS one.

Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain.

R. Vandenberg, I. Vetter, T. Rawling, 2019, Journal of medicinal chemistry.

The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site

R. Papke, J. Meiler, I. Vetter, 2021, bioRxiv.

Development of a O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8

D. Craik, I. Vetter, C. Schroeder, 2016 .

δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails

I. Vetter, Jennifer J. Smith, R. Lewis, 2015, Proceedings of the Royal Society B: Biological Sciences.

Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors.

D. Craik, I. Vetter, David John Adams, 2013, Biochemical pharmacology.

α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors.

I. Vetter, R. Lewis, N. Daly, 2015, Biochemical pharmacology.

Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin.

Irina Vetter, I. Vetter, R. Lewis, 2014, Neuro-oncology.

NaV1.1 and NaV1.6 selective compounds reduce the behavior phenotype and epileptiform activity in a novel zebrafish model for Dravet Syndrome

I. Vetter, B. Koeleman, K. Braun, 2020, PloS one.

A bivalent remipede toxin promotes calcium release via ryanodine receptor activation

I. Vetter, Jennifer J. Smith, M. Mobli, 2023, Nature Communications.

The response of dorsal root ganglion axons to nerve growth factor gradients depends on spinal level.

G. Goodhill, Z. Pujic, I. Vetter, 2010, Journal of neurotrauma.

A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals

I. Vetter, R. Norton, G. King, 2022, Proceedings of the National Academy of Sciences.

Venom Peptides as a Rich Source of Cav2.2 Channel Blockers

I. Vetter, R. Lewis, S. R. Sousa, 2013, Toxins.

Chemical Synthesis and Structure of the Prokineticin Bv8

D. Craik, I. Vetter, T. Durek, 2010, Chembiochem : a European journal of chemical biology.

Golgi Calcium Pump Secretory Pathway Calcium ATPase 1 (SPCA1) Is a Key Regulator of Insulin-like Growth Factor Receptor (IGF1R) Processing in the Basal-like Breast Cancer Cell Line MDA-MB-231*

I. Vetter, P. Kenny, Desma M. Grice, 2010, The Journal of Biological Chemistry.

Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides

I. Vetter, David John Adams, R. Lewis, 2018, Scientific Reports.

Neuronal cell lines as model dorsal root ganglion neurons

I. Vetter, G. Baillie, Kathleen Yin, 2016, Molecular pain.

Isolation and structural and pharmacological characterization of α-elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venom.

I. Vetter, T. Durek, R. Lewis, 2014, Biochemistry.

Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides.

D. Craik, I. Vetter, C. Schroeder, 2021, Bioconjugate chemistry.

No gain, no pain: NaV1.7 as an analgesic target.

Irina Vetter, I. Vetter, G. King, 2014, ACS chemical neuroscience.

Pharmacological activity and NMR solution structure of the leech peptide HSTX-I.

S. Dib-Hajj, S. Waxman, I. Vetter, 2020, Biochemical pharmacology.

The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant

I. Vetter, R. Lewis, G. King, 2017, PloS one.

The effects of pH on beta-endorphin and morphine inhibition of calcium transients in dorsal root ganglion neurons.

I. Vetter, P. Cabot, G. Monteith, 2006, The journal of pain : official journal of the American Pain Society.

Multipurpose peptides: the venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities.

I. Vetter, C. Schroeder, G. King, 2021, Biochemical pharmacology.

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

Samantha J. Stehbens, S. Dib-Hajj, S. Waxman, 2023, Nature communications.

Lethal effects of an insecticidal spider venom peptide involve positive allosteric modulation of insect nicotinic acetylcholine receptors

I. Vetter, R. Lewis, M. Windley, 2017, Neuropharmacology.

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

I. Vetter, C. Bladen, R. Lewis, 2017, PloS one.

Modulatory features of the novel spider toxin μ‐TRTX‐Df1a isolated from the venom of the spider Davus fasciatus

I. Vetter, Jennifer J. Smith, R. Lewis, 2017, British journal of pharmacology.

Seven novel modulators of the analgesic target NaV1.7 uncovered using a high‐throughput venom‐based discovery approach

I. Vetter, Jennifer J. Smith, G. King, 2015, British journal of pharmacology.

Recombinant production, bioconjugation and membrane binding studies ofPn3a, a selective NaV1.7 inhibitor.

I. Vetter, M. Mobli, J. Deuis, 2020, Biochemical pharmacology.

Neurotoxic peptides from the venom of the giant Australian stinging tree

D. Craik, D. Andersson, I. Vetter, 2020, Science Advances.

Assessment of the TRPM8 inhibitor AMTB in breast cancer cells and its identification as an inhibitor of voltage gated sodium channels

I. Vetter, P. Kenny, A. A. Peters, 2018, Life sciences.

An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a convenient Fluorescence Imaging Plate Reader assay.

W. Denny, I. Vetter, I. Azimi, 2018, Bioorganic & medicinal chemistry.

Changes in Potency and Subtype Selectivity of Bivalent NaV Toxins are Knot-Specific.

I. Vetter, C. Schroeder, R. Payne, 2023, Bioconjugate chemistry.

Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia

I. Vetter, R. Lewis, P. Reeh, 2016, Pain.

Expression and Pharmacology of Endogenous Cav Channels in SH-SY5Y Human Neuroblastoma Cells

I. Vetter, R. Lewis, L. Ragnarsson, 2013, PloS one.

Two Novel Mosquitocidal Peptides Isolated from the Venom of the Bahia Scarlet Tarantula (Lasiodora klugi)

I. Vetter, V. Herzig, M. Shuaibu, 2023, Toxins.

Conotoxin Φ-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity.

A. Loukas, I. Vetter, R. Lewis, 2017, Angewandte Chemie.

Structural Conformation and Activity of Spider-Derived Inhibitory Cystine Knot Peptide Pn3a Are Modulated by pH

I. Vetter, C. Schroeder, M. Mobli, 2023, ACS omega.

Anti-allodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute post-surgical pain: evidence for analgesic synergy with opioids and baclofen.

I. Vetter, O. Cheneval, C. Schroeder, 2019, Pain.

Pain-Causing Venom Peptides: Insights into Sensory Neuron Pharmacology

I. Vetter, S. Brierley, S. Jami, 2017, Toxins.

Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1.

I. Vetter, David John Adams, T. Durek, 2013, ACS chemical biology.

New Insight in Cold Pain: Role of Ion Channels, Modulation, and Clinical Perspectives

D. Andersson, I. Vetter, E. Leipold, 2016, The Journal of Neuroscience.

Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions.

I. Vetter, Q. Kaas, C. Schroeder, 2020, ACS pharmacology & translational science.

Transcriptome and proteome of Conus planorbis identify the nicotinic receptors as primary target for the defensive venom

I. Vetter, P. Alewood, S. Dutertre, 2015, Proteomics.

Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom

D. Craik, I. Vetter, J. T. Goulart, 2023, Scientific reports.

CHAPTER 1:Seeing the Woods for the Trees: Understanding Venom Evolution as a Guide for Biodiscovery

I. Vetter, K. Sunagar, Yves Terrat, 2015 .

Amplified Cold Transduction in Native Nociceptors by M-Channel Inhibition

C. Alzheimer, C. Belmonte, I. Vetter, 2013, The Journal of Neuroscience.

Venom chemistry underlying the painful stings of velvet ants (Hymenoptera: Mutillidae)

I. Vetter, G. King, S. Robinson, 2021, Cellular and Molecular Life Sciences.

Improving the Gastrointestinal Stability of Linaclotide

I. Vetter, P. Dawson, F. Albericio, 2021, Journal of medicinal chemistry.

Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens

I. Vetter, K. Rosengren, P. Alewood, 2015, Molecular Pharmacology.

Multiple actions of φ-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins

I. Vetter, Jennifer J. Smith, J. Tytgat, 2013, Proceedings of the National Academy of Sciences of the United States of America.

Comparative evolution of Psammophis and Echis snake venom metalloproteases (svmp)

I. Vetter, A. Antunes, R. Lewis, 2012 .

Chemotactic responses of growing neurites to precisely controlled gradients of nerve growth factor

Geoffrey J. Goodhill, Zac Pujic, Irina Vetter, 2018, Scientific Data.

Evaluation of Peptide Ligation Strategies for the Synthesis of the Bivalent Acid-Sensing Ion Channel Inhibitor Hi1a.

I. Vetter, C. Schroeder, R. Payne, 2023, Organic letters.

WITHDRAWN: Toxins in Neurobiology: new tools from old molecules.

I. Vetter, 2017, Neuroscience letters.

Golgi Calcium Pump Secretory Pathway Calcium ATPase 1 (SPCA1) Is a Key Regulator of Insulin-like Growth Factor Receptor (IGF1R) Processing in the Basal-like Breast Cancer Cell Line MDA-MB-231*

I. Vetter, P. Kenny, Desma M. Grice, 2010, The Journal of Biological Chemistry.

Ant venoms contain vertebrate-selective pain-causing sodium channel toxins

I. Vetter, Nina Brinkwirth, C. Schroeder, 2023, Nature communications.

Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNaV1.7 and hCaV3 voltage‐gated channels

I. Vetter, C. Schroeder, N. Daly, 2023, The FEBS journal.