J. Vadolas

发表

Integration of functional bacterial artificial chromosomes into human cord blood-derived multipotent stem cells

F. Zaibak, J. Kozlovski, J. Vadolas, 2009, Gene Therapy.

Gene therapy for inherited lung disorders: an insight into pulmonary defence.

J. Vadolas, R. Williamson, P. Ioannou, 2002, Pulmonary pharmacology & therapeutics.

DNA vaccines for bacterial infections

J. Vadolas, S. Dunstan, D. Drew, 1997, Immunology and cell biology.

Cellular genomic reporter assays for screening and evaluation of inducers of fetal hemoglobin.

J. Vadolas, R. Williamson, P. Ioannou, 2003, Human molecular genetics.

GFP to BFP Conversion: A Versatile Assay for the Quantification of CRISPR/Cas9-mediated Genome Editing

J. Vadolas, A. Glaser, B. McColl, 2016, Molecular therapy. Nucleic acids.

Corrigendum to GFP to BFP Conversion: A Versatile Assay for the Quantification of CRISPR/Cas9-mediated Genome Editing.

J. Vadolas, A. Glaser, B. McColl, 2016, Molecular Therapy: Nucleic Acids.

GFP to BFP Conversion: A Versatile Assay for the Quantification of CRISPR/Cas9-mediated Genome Editing.

J. Vadolas, A. Glaser, B. McColl, 2016, Molecular therapy. Nucleic acids.

Neutralization epitopes of human rhinovirus type 2.

J. Vadolas, B. Clarke, G. Appleyard, 1990, The Journal of general virology.

An in vivo model for analysis of developmental erythropoiesis and globin gene regulation

Linden J. Gearing, J. Vadolas, S. Fucharoen, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Heart rate variability in -thalassemic mice

J. Vadolas, N. Chattipakorn, S. Chattipakorn, 2007 .

Reduced PU.1 expression underlies aberrant neutrophil maturation and function in β-thalassemia mice and patients.

J. Vadolas, S. Fucharoen, P. Sutton, 2017, Blood.

Site-specific integration of bacterial artificial chromosomes into human cells.

J. Vadolas, S. Howden, B. McColl, 2015, Methods in molecular biology.

Development of a novel bacterial artificial chromosome cloning system for functional studies.

F. Zaibak, J. Vadolas, P. Ioannou, 2003, Plasmid.

Generation of a genomic reporter assay system for analysis of (cid:1) - and (cid:2) -globin gene regulation

S. Orkin, J. Vadolas, Jian Xu, 2020 .

The therapeutic potential of genome editing for β-thalassemia

J. Vadolas, A. Glaser, B. McColl, 2015, F1000Research.

SLN124, a GalNac‐siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron‐overload in a mouse model of β‐thalassaemia

J. Vadolas, P. Crouch, S. Dames, 2021, British journal of haematology.

Human Gene Therapy: Risks and Safety Considerations

J. Vadolas, P. Ioannou, 2006 .

Controlling α-globin: a review of α-globin expression and its impact on β-thalassemia

J. Vadolas, H. P. Voon, 2008, Haematologica.

Hepcidin and 1,25(OH)2D3 effectively restore Ca2+ transport in β-thalassemic mice: reciprocal phenomenon of Fe2+ and Ca2+ absorption.

J. Vadolas, S. Fucharoen, Sarawut Lapmanee, 2016, American journal of physiology. Endocrinology and metabolism.

The role of macrophages in the induction and regulation of immunity elicited by exogenous antigens

J. Vadolas, N. Van Rooijen, R. Strugnell, 1998, European journal of immunology.

Accumulation of lipid peroxidation‐derived DNA lesions in iron‐overloaded thalassemic mouse livers: Comparison with levels in the lymphocytes of thalassemia patients

H. Bartsch, J. Vadolas, S. Srichairatanakool, 2009, International journal of cancer.

Elevated levels of circulating monocytic myeloid derived suppressor cells in splenectomised β‐thalassaemia/HbE patients

J. Vadolas, S. Fucharoen, K. Pattanapanyasat, 2020, British journal of haematology.

ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level.

J. Vadolas, S. Jane, D. Curtis, 2013, Blood cells, molecules & diseases.

Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection

J. Vadolas, N. Van Rooijen, R. Strugnell, 1997, Journal of virology.

Increased autophagy leads to decreased apoptosis during β-thalassaemic mouse and patient erythropoiesis

J. Vadolas, S. Fucharoen, Duncan R. Smith, 2022, Scientific Reports.

Nucleic acid vaccination of sheep: Use in combination with a conventional adjuvanted vaccine against Taenia ovis

J. Vadolas, J. Waterkeyn, R. Strugnell, 1997, Immunology and Cell Biology.

Impaired neutrophil extracellular trap formation in β-thalassaemia/HbE

J. Vadolas, S. Fucharoen, K. Pattanapanyasat, 2022, Scientific Reports.

Mapping of neutralization epitopes of human rhinovirus type 2 with monoclonal antibodies

J. Vadolas, B. Clarke, G. Appleyard, 1989 .

A humanized BAC transgenic/knockout mouse model for HbE/β-thalassemia

F. Zaibak, J. Vadolas, R. Williamson, 2006 .

A humanized mouse model for a common β0-thalassemia mutation

F. Zaibak, J. Vadolas, R. Williamson, 2005 .

Trienone analogs of curcuminoids induce fetal hemoglobin synthesis via demethylation at Gγ-globin gene promoter

J. Vadolas, A. Suksamrarn, S. Svasti, 2021, Scientific Reports.

A humanized BAC transgenic/knockout mouse model for HbE/beta-thalassemia.

F. Zaibak, J. Vadolas, R. Williamson, 2006, Genomics.

Site-specific, Rep-mediated integration of the intact β-globin locus in the human erythroleukaemic cell line K562

J. Vadolas, R. Williamson, S. Howden, 2008, Gene Therapy.

A 191-kb genomic fragment containing the human α-globin locus can rescue α-thalassemic mice

J. Vadolas, R. Williamson, L. Voullaire, 2005, Mammalian Genome.

Heart rate variability in beta-thalassemic mice.

J. Vadolas, N. Chattipakorn, S. Chattipakorn, 2007, International journal of cardiology.

Labdane diterpenes from the aerial parts of Curcuma comosa enhance fetal hemoglobin production in an erythroid cell line.

J. Vadolas, S. Fucharoen, A. Suksamrarn, 2010, Journal of natural products.

Epigenetic interplay at the β-globin locus.

J. Vadolas, J. Maksimovic, B. McColl, 2017, Biochimica et biophysica acta. Gene regulatory mechanisms.

Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β‐like globin genes

Linden J Gearing, Jim Vadolas, Linden J. Gearing, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia

J. Vadolas, S. Fucharoen, G. Grigoriadis, 2021, Molecular therapy : the journal of the American Society of Gene Therapy.

Generation of a genomic reporter assay system for analysis of γ‐ and β‐globin gene regulation

S. Orkin, J. Vadolas, Jian Xu, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Development of sensitive fluorescent assays for embryonic and fetal hemoglobin inducers using the human beta -globin locus in erythropoietic cells.

F. Zaibak, J. Vadolas, R. Williamson, 2002, Blood.

Imbalanced globin chain synthesis determines erythroid cell pathology in thalassemic mice

J. Vadolas, S. Fucharoen, S. Svasti, 2009, Haematologica.

Transgene copy number-dependent rescue of murine β-globin knockout mice carrying a 183 kb human β-globin BAC genomic fragment

F. Zaibak, J. Vadolas, R. Williamson, 2005 .

A 191-kb genomic fragment containing the human alpha-globin locus can rescue alpha-thalassemic mice.

J. Vadolas, R. Williamson, L. Voullaire, 2005, Mammalian genome : official journal of the International Mammalian Genome Society.

Transgene copy number-dependent rescue of murine beta-globin knockout mice carrying a 183 kb human beta-globin BAC genomic fragment.

F. Zaibak, J. Vadolas, R. Williamson, 2005, Biochimica et biophysica acta.

The transient expression of mRNA coding for Rep protein from AAV facilitates targeted plasmid integration

J. Vadolas, S. Howden, L. Voullaire, 2008, The journal of gene medicine.

Humanized β-Thalassemia Mouse Model Containing the Common IVSI-110 Splicing Mutation*

M. Nefedov, J. Vadolas, R. Williamson, 2006, Journal of Biological Chemistry.

Chromatin-binding regions of EBNA1 protein facilitate the enhanced transfection of Epstein-Barr virus-based vectors.

J. Vadolas, R. Williamson, S. Howden, 2006, Human gene therapy.

Targeted gene correction in the mdx mouse using short DNA fragments: towards application with bone marrow-derived cells for autologous remodeling of dystrophic muscle

J. Vadolas, R. Kapsa, A. Quigley, 2002, Gene Therapy.

Reversal of cardiac iron loading and dysfunction in thalassemic mice by curcuminoids.

J. Vadolas, N. Chattipakorn, S. Srichairatanakool, 2011, Medicinal chemistry (Shariqah (United Arab Emirates)).

Animal models of β-hemoglobinopathies: utility and limitations

J. Vadolas, B. McColl, 2016, Journal of blood medicine.

Complementation of α-thalassaemia in α-globin Knockout Mice with a 191 kb Transgene Containing the Human α-Globin Locus

J. Vadolas, R. Williamson, L. Voullaire, 2004, Transgenic Research.

Intranasal immunization with yeast‐expressed 19 kD carboxyl‐terminal fragment of Plasmodium yoelii merozoite surface protein‐1 (yMSP119) induces protective immunity to blood stage malaria infection in mice

J. Vadolas, D. Kaslow, M. Good, 1998, Parasite immunology.

Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin

Laura J. Norton, J. Vadolas, K. Quinlan, 2015, Nature Communications.

A comprehensive study of immune function and immunophenotyping of white blood cells from β‐thalassaemia/HbE patients on hydroxyurea supports the safety of the drug

J. Vadolas, S. Fucharoen, K. Pattanapanyasat, 2022, British journal of haematology.

Increased ferritin levels in non‐transfusion‐dependent β°‐thalassaemia/HbE are associated with reduced CXCR2 expression and neutrophil migration

J. Vadolas, S. Fucharoen, K. Pattanapanyasat, 2019, British journal of haematology.

siRNA-mediated reduction of α-globin results in phenotypic improvements in β-thalassemic cells

J. Vadolas, H. Wardan, H. P. Voon, 2008, Haematologica.

Generation of BAC reporter cell lines for drug discovery.

J. Vadolas, B. McColl, B. Kao, 2015, Methods in molecular biology.

Intranasal immunization with liposomes induces strong mucosal immune responses in mice

J. Vadolas, R. Strugnell, J. Davies, 1995, European journal of immunology.

Gene induction for the treatment of methylmalonic aciduria

J. Vadolas, J. Sarsero, M. Khaniani, 2009, The journal of gene medicine.

ErythRED, a hESC line enabling identification of erythroid cells

E. Stanley, J. Vadolas, A. Elefanty, 2009, Nature Methods.

The Potential of Bone Marrow Stem Cells to Correct Liver Dysfunction in a Mouse Model of Wilson's Disease

J. Vadolas, P. Ioannou, K. Allen, 2004, Cell Transplantation.

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

E. Stanley, S. Petrou, J. Vadolas, 2016, Stem cell reports.

A reduced curcuminoid analog as a novel inducer of fetal hemoglobin

J. Vadolas, S. Fucharoen, A. Suksamrarn, 2013, Annals of Hematology.

Lipofection of Non-integrative CRISPR/Cas9 Ribonucleoproteins in Male Germline Stem Cells: A Simple and Effective Knockout Tool for Germline Genome Engineering

J. Vadolas, S. Verhulst, E. Goossens, 2022, Frontiers in Cell and Developmental Biology.

Engineering EGFP reporter constructs into a 200 kb human beta-globin BAC clone using GET Recombination.

M. Nefedov, F. Zaibak, J. Vadolas, 2000, Nucleic acids research.

Corrigendum to GFP to BFP Conversion: A Versatile Assay for the Quantification of CRISPR/Cas9-mediated Genome Editing

J. Vadolas, A. Glaser, B. McColl, 2016, Molecular therapy. Nucleic acids.

A humanized mouse model for a common beta0-thalassemia mutation.

F. Zaibak, J. Vadolas, R. Williamson, 2005, Genomics.

Animal models of β-hemoglobinopathies: utility and limitations

J. Vadolas, B. McColl, 2016, Journal of blood medicine.

An in vivo model for analysis of developmental erythropoiesis and globin gene regulation

Linden J. Gearing, J. Vadolas, S. Fucharoen, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.