A. Howlett

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Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

M. Bissell, O. Petersen, L. Rønnov-Jessen, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The influence of tissue microenvironment (stroma and extracellular matrix) on the development and function of mammary epithelium.

M. Bissell, A. Howlett, Anthony R. Howlett, 1993, Epithelial cell biology.

Improved effect of an antiangiogenic tyrosine kinase inhibitor (SU5416) by combinations with fractionated radiotherapy or low molecular weight heparin.

A. Howlett, P. Kristjansen, G. Mcmahon, 2003, Neoplasia.

pp60v-src tyrosine kinase is expressed and active in sarcoma-free avian embryos microinjected with Rous sarcoma virus.

M. Bissell, A. Howlett, G. Martin, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Recent developments in drug resistance and apoptosis research.

A. Howlett, M. Clynes, L. Connolly, 1998, Critical reviews in oncology/hematology.

Free light chain synthesis by neoplastic cells in chronic lymphocytic leukaemia and non-Hodgkin's lymphoma.

A. Howlett, J. Smith, J. Gordon, 1978, Immunology.

Regulation of mammary epithelial cell function: a role for stromal and basement membrane matrices

M. Bissell, A. Howlett, 1990, Protoplasma.

The tyrosine phosphorylation substrate p36 is developmentally regulated in embryonic avian limb and is induced in cell culture

M. Bissell, A. Howlett, G. Martin, 1986, The Journal of cell biology.

Epithelial-stromal interactions in the adult bladder: urothelial growth, differentiation, and maturation on culture facsimiles of bladder stroma.

A. Howlett, C. Rowlatt, G. Hodges, 1986, Developmental biology.

Lactoferrin expression in mammary epithelial cells is mediated by changes in cell shape and actin cytoskeleton.

A. Howlett, P. Yaswen, M. Stampfer, 1997, Journal of cell science.

An ultrastructural analysis of the physical organization of collagenous (type I) matrices: one determinant of urothelium maintenance in vitro.

A. Howlett, L. Trejdosiewicz, C. Rowlatt, 1985, Scanning electron microscopy.

Voreloxin, a first-in-class anticancer quinolone derivative, acts synergistically with cytarabine in vitro and induces bone marrow aplasia in vivo

A. Howlett, C. Scatena, R. Hawtin, 2010, Cancer Chemotherapy and Pharmacology.

Use of ribozymes and antisense oligodeoxynucleotides to investigate mechanisms of drug resistance

A. Howlett, M. Clynes, C. Daly, 1998, Cytotechnology.

The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

D. Khatry, G. Manning, D. Whyte, 2003, Molecular and Cellular Biology.

The development of a functionally relevant cell culture model of progressive human breast cancer.

M J Bissell, V. Weaver, M. Bissell, 1995, Seminars in cancer biology.

Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase

K. Furge, A. Howlett, G. Woude, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A Novel Function for the nm23-Hl Gene: Overexpression in Human Breast Carcinoma Cells Leads to the Formation of Basement Membrane and Growth Arrest

M J Bissell, M. Bissell, O. Petersen, 2010 .

Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion.

A. Howlett, G. Mcmahon, C. Liang, 2003, Molecular cancer therapeutics.

SU5416 and SU6668 attenuate the angiogenic effects of radiation-induced tumor cell growth factor production and amplify the direct anti-endothelial action of radiation in vitro.

J. Debus, P. Hahnfeldt, L. Hlatky, 2003, Cancer research.

The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants

L. Schmidt, A. Howlett, D. Candinas, 2004, Oncogene.

Cellular growth and survival are mediated by beta 1 integrins in normal human breast epithelium but not in breast carcinoma.

M J Bissell, M. Bissell, O. Petersen, 1995, Journal of cell science.

Negative Cooperativity between α3β1and α2β1Integrins in Human Mammary Carcinoma MDA MB 231 Cells

Martin R. Schneider, A. Howlett, R. Lichtner, 1998 .

Cell differentiation by extracellular matrix components.

M. Bissell, O. Petersen, A. Howlett, 1994, Methods in enzymology.

Adventitial microvessel formation after coronary stenting and the effects of SU11218, a tyrosine kinase inhibitor.

Michael J. Cole, R. Virmani, F. Kolodgie, 2006, Journal of the American College of Cardiology.

SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization

A. Howlett, G. Mcmahon, O. Hammarsten, 2004, Oncogene.

SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo

R. Fucini, A. Howlett, Brian J. Belmont, 2010, Cancer Chemotherapy and Pharmacology.

A Selective and Oral Small Molecule Inhibitor of Vascular Epithelial Growth Factor Receptor (VEGFR)-2 and VEGFR-1 Inhibits Neovascularization and Vascular Permeability

A. Howlett, G. Mcmahon, Qingling Zhang, 2003, Journal of Pharmacology and Experimental Therapeutics.

Negative cooperativity between alpha 3 beta 1 and alpha 2 beta 1 integrins in human mammary carcinoma MDA MB 231 cells.

A. Howlett, R. Lichtner, M. Schneider, 1998, Experimental Cell Research.

Tissue tropism and temporal expression of Rous sarcoma virus in embryonic avian limb in ovo.

M. Bissell, A. Howlett, B. Cullen, 1987, Oncogene research.

SNS-032 has potent antitumor activity in vivo against human leukemia and multiple myeloma xenografts

Jeffrey A Jones, A. Howlett, P. Taverna, 2007 .

A Cell-Based Adhesion Assay for the Characterization of Integrin α v β 3 Antagonists

A. Howlett, R. Feldman, M. Rosser, 1999 .