R. Schwartz

发表

R. Schwartz, 2003, Annual review of immunology.

Antigen presentation by chemically modified splenocytes induces antigen- specific T cell unresponsiveness in vitro and in vivo

R. Schwartz, M. Jenkins, R H Schwartz, 1987, The Journal of experimental medicine.

Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells.

R. Schwartz, M. Jenkins, J. Ashwell, 1988, Journal of immunology.

Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy.

R. Schwartz, M. Jenkins, D. Mueller, 1989, Annual review of immunology.

TC ELL ANERGY

R. Schwartz, 2003 .

Anergy, T Cell

R. Schwartz, 1998 .

A cell culture model for T lymphocyte clonal anergy.

R. Schwartz, R H Schwartz, 1990, Science.

Models of T Cell Anergy: Is There a Common Molecular Mechanism?

R. Schwartz, Ronald H. Schwartz, 1996 .

The role of CD28 in the activation of T lymphocytes to proliferate in response to IL4.

R. Schwartz, L. Chiodetti, 1995, Research in immunology.

T-cell clonal anergy.

R. Schwartz, M. Jenkins, D. Mueller, 1997, Cold Spring Harbor symposia on quantitative biology.

A subtractive PCR-based cDNA library made from fetal thymic stromal cells.

R. Germain, R. Schwartz, M. G. Kim, 1998, Journal of immunological methods.

A Putative 12 Transmembrane Domain Cotransporter Expressed in Thymic Cortical Epithelial Cells

R. Schwartz, M. G. Kim, F. Flomerfelt, 2000, The Journal of Immunology.

Characterization of the mouse gene, human promoter and human cDNA of TSCOT reveals strong interspecies homology.

R. Schwartz, C. Kozak, M. G. Kim, 2000, Biochimica et biophysica acta.

The lymphopenic mouse in immunology: from patron to pariah.

R. Schwartz, Nevil J. Singh, 2006, Immunity.

4 – T Cell Anergy

K. Brorson, R. Schwartz, D. Mueller, 1993 .

Promoter IL-2 Changes at the Activated Causes Sequential Chromatin Structural Two-Step Binding of Transcription Factors

S. Ishihara, R. Schwartz, 2011 .

A quantitative analysis of antigen-presenting cell function: activated B cells stimulate naive CD4 T cells but are inferior to dendritic cells in providing costimulation

R. Schwartz, D. Cassell, 1994, The Journal of experimental medicine.

Immune response (Ir) genes of the murine major histocompatibility complex.

R. Schwartz, 1986, Advances in immunology.

Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists.

R. Germain, R. Schwartz, J. Madrenas, 1996, Proceedings of the National Academy of Sciences of the United States of America.

A novel population of T-cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family

J. Coligan, R. Schwartz, D. Pardoll, 1987, Nature.

Tbata modulates thymic stromal cell proliferation and thymus function

R. Schwartz, V. Kapoor, R. Gress, 2010, The Journal of experimental medicine.

Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2

R. Schwartz, T. Miyata, Y. Oh, 2015, Nature Communications.

Activated, and Anergic T Cells and IL-2 Production by Naive, Previously Distinct Requirements for C-C Chemokine

M. Horton, R. Schwartz, J. Powell, 2000 .

Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

R. Schwartz, D. Pardoll, B. Fowlkes, 1988, Nature.

Subsets of nonclonal neighboring CD4+ T cells specifically regulate the frequency of individual antigen-reactive T cells.

R. Schwartz, Jennifer K. Bando, Nevil J. Singh, 2012, Immunity.

The molecular basis of class II MHC allelic control of T cell responses.

R. Germain, L. Racioppi, R. Schwartz, 1991, Journal of immunology.

Processing of a minimal antigenic peptide alters its interaction with MHC molecules

R. Germain, R. Schwartz, F. Carbone, 1988, Nature.

Quantitative analysis of the T cell response to antigen and planar membranes containing purified Ia molecules.

R. Schwartz, H. Quill, L. Carlson, 1987, Journal of immunology.

Tenth Annual Meeting of the European Association for the Study of Diabetes

A. J. Honour, W. A. Müller, P. Blackshear, 1974, Diabetologia.

Demonstration that monocytes rather than lymphocytes are the insulin-binding cells in preparations of humah peripheral blood mononuclear leukocytes: implications for studies of insulin-resistant states in man.

C. Kahn, R. Schwartz, A. Bianco, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Formation in Adaptively Tolerant T Cells Impairment of Immunological Synapse

R. Schwartz, Seeyoung Choi, 2011 .

Activation of gamma delta T cells in the primary immune response to Mycobacterium tuberculosis.

S. Kaufmann, R. Schwartz, D. Pardoll, 1989, Science.

Diminished antigen processing by endosomal acidification mutant antigen-presenting cells.

R. Germain, R. Schwartz, F. Ronchese, 1989, Journal of immunology.

Specific gut commensal flora locally alters T cell tuning to endogenous ligands.

R. Schwartz, N. Bouladoux, S. Naik, 2013, Immunity.

Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains

R. Schwartz, C. Kozak, M. Lyu, 1999, Immunogenetics.

A N T I G E N P R E S E N T A T I O N BY RESTING B CELLS Radiosensitivity of the Antigen-Presentation Function and Two Distinct Pathways of T Cell Activation

W. Paul, R. Schwartz, 2003 .

Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation

W. Paul, R. Schwartz, J. Ashwell, 1984, The Journal of experimental medicine.

Analysis of T-cell receptor gamma chain expression in the thymus.

J. Coligan, J. Bluestone, R. Schwartz, 1987, Advances in experimental medicine and biology.

The unfolding story of T cell receptor γ

J. Coligan, R. Schwartz, B. Fowlkes, 1987, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Effects of cyclosporine A on T cell development and clonal deletion.

R. Schwartz, D. Pardoll, M. Jenkins, 1988, Science.

Low-Dose Radiation Plus Rapamycin Promotes Long-Term Bone Marrow Chimerism

R. Schwartz, J. Powell, J. Tisdale, 2005, Transplantation.

Immunology: It takes more than two to tango

R. Schwartz, 2001, Nature.

Antigen-induced suppression of the proliferative response of T cell clones.

R. Schwartz, G. Suzuki, S. Koyasu, 1988, Journal of immunology.

Thymus-dependent and thymus-independent developmental pathways for peripheral T cell receptor-gamma delta-bearing lymphocytes.

J. Coligan, J. Bluestone, R. Schwartz, 1988, Journal of immunology.

Activation properties of T cell receptor-gamma delta hybridomas expressing diversity in both gamma- and delta-chains.

J. Coligan, R. Germain, R. Schwartz, 1988, Journal of immunology.

Inhibition of antigen-induced proliferation of T cells from radiation-induced bone marrow chimeras by a monoclonal antibody directed against an Ia determinant on the antigen-presenting cell.

D. Longo, R. Schwartz, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of dual Ir gene-controlled T-lymphocyte proliferative response to poly (Glu56Lys35Phe9)n with anti-Ia antisera directed against products of either I-A or I-C subregion.

W. Paul, R. Schwartz, B. Benacerraf, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Cell Reactivity in Adaptive Tolerance Production but Is Not Required for Tuning T T Cell Proliferation and Cytokine +CTLA-4 Engagement Acts as a Brake on CD4

R. Schwartz, M. Inobe, 2004 .

The destabilization of IL-2 mRNA by a premature stop codon and its differential stabilization by trans-acting inhibitors of protein synthesis do not support a role for active translation in mRNA stability.

R. Schwartz, J. Ragheb, M. Deen, 1999, Journal of immunology.

Active Translation in mRNA Stability Protein Synthesis Do Not Support a Role for-Acting Inhibitors of Trans Stabilization by Premature Stop Codon and Its Differential The Destabilization of IL-2 mRNA by a

R. Schwartz, J. Ragheb, M. Deen, 1999 .

T cell clonal anergy.

R. Schwartz, 1997, Current opinion in immunology.

Distinct Biochemical States Adaptive Tolerance and Clonal Anergy Are

R. Schwartz, D. Barber, Seeyoung Choi, 2006 .

Adaptive Tolerance of CD4+ T Cells In Vivo: Multiple Thresholds in Response to a Constant Level of Antigen Presentation

R. Schwartz, D. Barber, L. Chiodetti, 2001, The Journal of Immunology.

An acid protease secreted by transformed cells interferes with antigen processing

M. Gottesman, R. Schwartz, K. McCoy, 1988, The Journal of cell biology.

The B10.A mouse B cell response to pigeon cytochrome c is directed against the same area of the protein that is recognized by B10.A T cells in association with the Ek beta:Ek alpha Ia molecule.

E. Margoliash, R. Schwartz, L. Matis, 1985, Journal of immunology.

The value of synthetic peptides as vaccines for eliciting T-cell immunity.

R. Schwartz, 1986, Current topics in microbiology and immunology.

The Role of Intracellular Acidification in Antigen Processing

R. Schwartz, K. McCoy, 1988, Immunological reviews.

Functionally distinct subsites on a class II major histocompatibility complex molecule

R. Germain, R. Schwartz, F. Ronchese, 1987, Nature.

Fugue in T-lymphocyte recognition

R. Schwartz, 1987, Nature.

Functional analysis of the antigenic structure of a minor T cell determinant from pigeon cytochrome C. Evidence against an alpha-helical conformation.

R. Schwartz, W. Maloy, K. Ogasawara, 1989, Journal of immunology.

T-cell recognition of antigen and the Ia molecule as a ternary complex

R. Schwartz, J. Ashwell, 1986, Nature.

The molecular basis of the requirement for antigen processing of pigeon cytochrome c prior to T cell activation.

R. Schwartz, Z. Kovač, 1985, Journal of immunology.

Correlation between the conformation of cytochrome c peptides and their stimulatory activity in a T-lymphocyte proliferation assay.

M. Pincus, H. Scheraga, R. Schwartz, 1983, Proceedings of the National Academy of Sciences of the United States of America.

An intracellular calcium increase and protein kinase C activation fail to initiate T cell proliferation in the absence of a costimulatory signal.

R. Schwartz, M. Jenkins, D. Mueller, 1990, Journal of immunology.

Functionally distinct agretopic and epitopic sites. Analysis of the dominant T cell determinant of moth and pigeon cytochromes c with the use of synthetic peptide antigens.

R. Schwartz, B. Singh, C. French, 1987, Journal of immunology.

T cell clone-specific alloantisera that inhibit or stimulate antigen-induced T cell activation.

R. Schwartz, L. Samelson, 1983, Journal of immunology.

The fine specificity of antigen and la determinant recognition by T cell hybridoma clones specific for pigeon cytochrome c

D. Longo, R. Schwartz, L. Matis, 1982, Cell.

Thymic skewing of the CD4/CD8 ratio maps with the T-cell receptor α-chain locus

R. Schwartz, D. Lo, N. Gascoigne, 1998, Current Biology.

At low precursor frequencies, the T‐cell response to chronic self‐antigen results in anergy without deletion

R. Schwartz, Elizabeth M. Steinert, Nevil J. Singh, 2012, European journal of immunology.

Faculty Opinions recommendation of Antigen-specific modulation of an immune response by in vivo administration of soluble MHC class I tetramers.

R. Schwartz, 2001 .

Faculty Opinions recommendation of Antagonistic roles for CTLA-4 and the mammalian target of rapamycin in the regulation of clonal anergy: enhanced cell cycle progression promotes recall antigen responsiveness.

R. Schwartz, 2001 .

Two-signal Models of Lymphocyte Activation

R. Schwartz, 1995 .

Immunology: Induction of tolerance to self in T lymphocytes

R. Schwartz, 1984, Nature.

A Clonal Deletion Model for Ir Gene Control of the Immune Response

R. Schwartz, 1978, Scandinavian journal of immunology.

T -LYMPHOCYTE RECOGNITION OF ANTIGEN IN

R. Schwartz, 1985 .

Characterization of the Antigen‐Specific T Cell Receptor from a Pigeon Cytochrome c‐Specific T Cell Hybrid

R. Schwartz, L. Samelson, 1984, Immunological reviews.

Interaction Between Antigen‐Presenting Cells and Primed T Lymphocytes

W. Paul, R. Schwartz, A. Yano, 1978, Immunological reviews.

Antigen‐Specific, Proliferating T Lymphocyte Clones. Methodology, Specificity, MHC Restriction and Alloreactivity

R. Schwartz, B. Sredni, 1981, Immunological reviews.

Gene complementation in the T lymphocyte proliferative response to poly(Glu56Lys35Phe9)nFunctional evidence for a restriction element coded for by both the I‐A and I‐E subregions

W. Paul, R. Schwartz, C. Chen, 1980, European journal of immunology.

T lymphocyte-enriched murine peritoneal exudate cells. III. Inhibition of antigen-induced T lymphocyte Proliferation with anti-Ia antisera.

W. Paul, R. Schwartz, D. Sachs, 1976, Journal of immunology.

Cloning of antigen-specific mhc-restricted proliferating t lymphocytes. Abstr.

R. Schwartz, H. Tse, B. Sredni, 1980 .

31 – Alloreactivity of Antigen-Specific T Cell Clones

R. Schwartz, B. Sredni, 1982 .

Alloreactivity of an antigen-specific T-cell clone

R. Schwartz, B. Sredni, 1980, Nature.

Studies of Ia Antigens on Murine Peritoneal Macrophages

R. Schwartz, D. Sachs, B. Schwartz, 1976, Scandinavian journal of immunology.

T-lymphocyte-enriched murine peritoneal exudate cells. II. Genetic control of antigen-induced T-lymphocyte proliferation

W. Paul, R. Schwartz, 1976, The Journal of experimental medicine.

CELLS II. Genetic Control of Antigen-Induced T-Lymphocyte Proliferation

W. Paul, R. Schwartz, 1976 .

THE ROLE OF Ia ANTIGENS IN MLC STIMULATION

R. Schwartz, D. Sachs, C. Fathman, 1976 .

T Cell Depending on the Differentiation State of the Dual Effects of Sprouty1 on TCR Signaling

R. Schwartz, Kyungho Choi, Heonsik Choi, 2006 .

24 – T Cell Recognition of Antigen and Ia Molecules Involves a Trimolecular Complex

R. Schwartz, J. Ashwell, B. Fox, 1988 .

The Use of Antisera and Monoclonal Antibodies to Identify the Antigen‐specific T Cell Receptor from Pigeon Cytochrome c‐Specific T Cell Hybrids

R. Schwartz, L. Samelson, 1983, Immunological reviews.

The cloning of T lymphocytes.

R. Schwartz, Ronald H. Schwartz, 1982, Immunology today.

The requirement for two complementing Ir-GLphi immune response genes in the T-lymphocyte proliferative response to poly-(Glu53Lys36Phe11)

W. Paul, R. Schwartz, B. Benacerraf, 1976, The Journal of experimental medicine.

Gene complementation. Neither Ir-GLphi gene need be present in the proliferative T cell to generate an immune response to Poly(Glu55Lys36Phe9)n

D. Longo, R. Schwartz, 1980, The Journal of experimental medicine.

Multifactor cis-dominant negative regulation of IL-2 gene expression in anergized T cells.

R. Schwartz, S. Kitagawa-Sakakida, 1996, Journal of immunology.

A 20-kDa protein associated with the murine T-cell antigen receptor is phosphorylated in response to activation by antigen or concanavalin A.

R. Klausner, R. Schwartz, L. Samelson, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Separation of murine lymphoid cells using nylon wool columns. Recovery of the B cell-enriched population.

R. Schwartz, B. Handwerger, Handwerger Bs, 1974, Transplantation.

Polyclonal stimulation of resting B lymphocytes by antigen-specific T lymphocytes

W. Paul, R. Schwartz, J. Ashwell, 1984, The Journal of experimental medicine.

Long-term growth and cloning of non-transformed lymphocytes

W. Paul, R. Schwartz, B. Sredni, 1981, Nature.

Development and Tolerization of Hyperacute Rejection in a Transgenic Mouse Graft Versus Host Model

R. Schwartz, Nevil J. Singh, Soyoung A Oh, 2012, Transplantation.

Histocompatibility Molecules as Immune Response Gene Products

R. Schwartz, L. Matis, Z. Kovač, 1985 .

N-terminal Processing Is Essential for Release of Epithin, a Mouse Type II Membrane Serine Protease*

R. Schwartz, I. Seong, Seung-Ryul Kim, 2001, The Journal of Biological Chemistry.

37 – Human T Cell Clones Reactive with Soluble Antigens: Methodology, Specificity, and MHC Restriction

A. Fauci, R. Schwartz, B. Sredni, 1982 .

I region-restricted antigen presentation by B cell–B lymphoma hybridomas

W. Paul, R. Schwartz, L. Glimcher, 1982, Nature.

Antigen-specific human T-cell clones: development of clones requiring HLA-DR-compatible presenting cells for stimulation in presence of antigen.

A. Fauci, R. Schwartz, B. Sredni, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Gene complementation in the T-lymphocyte proliferative response to poly (Glu55Lys36Phe9)n. A demonstration that both immune response gene products must be expressed in the same antigen-presenting cell

W. Paul, R. Schwartz, A. Yano, 1979, The Journal of experimental medicine.

The Effect of Nominal Antigen and Ia Molecule Concentrations on the Magnitude of the Proliferative Response of T Cell Clones

D. Longo, R. Schwartz, L. Glimcher, 1983 .

Inhibition of stimulation in murine mixed lymphocyte cultures with an alloantiserum directed against a shared Ia determinant.

R. Schwartz, D. Sachs, C. Fathman, 1976, Journal of immunology.

Regulation of interleukin 2 gene expression by CD28 costimulation in mouse T-cell clones: both nuclear and cytoplasmic RNAs are regulated with complex kinetics

R. Schwartz, O. Lantz, B. Beverly, 1995, Molecular and cellular biology.

Induction and maintenance of anergy in mature T cells.

R. Schwartz, M. Jenkins, D. Mueller, 1991, Advances in experimental medicine and biology.

Functional analysis of the interaction of the antigen-specific T cell receptor with its ligands.

R. Schwartz, J. Ashwell, B. Fox, 1986, Journal of immunology.

Clonal analysis of the major histocompatibility complex restriction and the fine specificity of antigen recognition in the T cell proliferative response to cytochrome C.

E. Margoliash, D. Longo, R. Schwartz, 1983, Journal of immunology.

Th0 Cells in the Thymus: The Question of T‐Helper Lineages

R. Schwartz, A. Bendelac, 1991, Immunological reviews.

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

R. Schwartz, 1992, Cell.

IS A UNIQUE T CELL REPERTOIRE GENERATED IN THE THYMUS

R. Schwartz, 1980 .

T-lymphocyte-enriched murine peritoneal exudate cells. IV. Genetic control of cross-stimulation at the T-cell level

W. Paul, R. Schwartz, C. L. Horton, 1977, Journal of Experimental Medicine.

T-LYMPHOCYTE-ENR ICHED MURINE PERITONEAL

W. Paul, R. Schwartz, Exudate Cells, 1977 .

Monoclonal antibodies against the antigen receptor on a cloned

R. Germain, R. Schwartz, L. Samelson, 1999 .

Molecular immunology: Associations in T-cell activation

R. Schwartz, 1985, Nature.

Direct cloning and extended culture of antigen-specific MHC-restricted, proliferating T lymphocytes

R. Schwartz, H. Tse, B. Sredni, 1980, Nature.

ANTIGEN-PRESENTING LYMPHOID TUMORS IN THE MURINE T LYMPHOCYTE PROLIFERATIVE RESPONSE TO DNP-OVALBUMIN AND POLY (GLU55LYS36PHE9)

W. Paul, R. Schwartz, R. Asofsky, 1980 .

Optimization of antigen presentation to T cell hybridomas by purified Ia molecules in planar membranes. Ia molecule polymorphism determines the antigenic fine specificity of the response to cytochrome c peptides.

J. Weinstein, R. Schwartz, H. Quill, 1987, Journal of immunological methods.

Development and characterization of trinitrophenyl-specific L3T4+ T-cell clones.

R. Schwartz, S. Shimada, S. Katz, 1986, The Journal of investigative dermatology.

Basic Features of Cellular Interactions in the Immune System a

R. Schwartz, 1987, Annals of the New York Academy of Sciences.

Failure to find holes in the T-cell repertoire

R. Schwartz, W. Maloy, K. Ogasawara, 1987, Nature.

Cotransporter Expressed in Thymic Cortical A Putative 12 Transmembrane Domain

R. Schwartz, F. Flomerfelt, M. Kim, 2013 .

The Effect of Antigen and Ia Molecule Interaction on Immune Response Gene Control

R. Schwartz, E. Heber-Katz, 1983 .

The nature of immune response gene defects

R. Schwartz, 1982, Nature.

The use of hydrophobic, alpha-helix-defined peptides in delineating the T cell determinant for pigeon cytochrome c.

R. Schwartz, F. Carbone, Y. Paterson, 1987, Journal of immunology.

Antigen presentation in the murine T lymphocyte proliferative response. II. Ir‐GAT‐controlled T lymphocyte responses require antigen‐presenting cells from a high responder donor

W. Paul, R. Schwartz, A. Yano, 1978, European journal of immunology.

ANTIGEN PRESENTATION IN THE T-LYMPHOCYTE PROLIFERATION ASSAY: REQUIREMENT FOR GENETIC IDENTITY AT THE MAJOR HISTOCOMPATIBILITY COMPLEX

W. Paul, R. Schwartz, A. Yano, 1978 .

Activation events during thymic selection

W. Paul, R. Schwartz, P. Matzinger, 1992, The Journal of experimental medicine.

Host Resistance and Immune Deviation in Pigeon Cytochromec T-Cell Receptor Transgenic Mice Infected withToxoplasma gondii

A. Sher, R. Schwartz, G. Yap, 2000, Infection and Immunity.

Primer: mechanisms of immunologic tolerance

R. Schwartz, Nevil J. Singh, 2006, Nature Clinical Practice Rheumatology.

Non-parametric, hypothesis-based analysis of microarrays for comparison of several phenotypes

Jeanne Kowalski, Jonathan Powell, Charles G. Drake, 2004, Bioinform..

Acquisition of immunologic self-tolerance

R. Schwartz, 1989, Cell.

Antigen-specific clones of proliferating T lymphocytes. I. Methodology, specificity, and MHC restriction.

R. Schwartz, H. Tse, B. Sredni, 1981, Journal of immunology.

T-cell specificity for H–2 and Ir gene phenotype correlates with the phenotype of thymic antigen-presenting cells

D. Longo, R. Schwartz, 1980, Nature.

Cell-cell interactions in the T cell proliferative response. I. Analysis of the cell types involved and evidence for nonspecific T cell recruitment.

W. Paul, R. Schwartz, H. Tse, 1980, Journal of immunology.

Natural regulatory T cells and self-tolerance

R. Schwartz, Ronald H Schwartz, 2005, Nature Immunology.

T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex.

R. Schwartz, 1985, Annual review of immunology.

Themis is a member of a new metazoan gene family and is required for completion of thymocyte positive selection

L. Aravind, R. Schwartz, C. Goodnow, 2009, Nature Immunology.

Genetic control of the immune response to staphylococcal nuclease in mice.

A. Schechter, J. Berzofsky, D. Pisetsky, 1978, Advances in experimental medicine and biology.

Morphological‐Biochemical Correlations in Rabbit Red Cell Precursors Synchronized by Actinomycin Administration

R. Schwartz, C. Hershko, G. Izak, 1969, British journal of haematology.

Two-Step Binding of Transcription Factors Causes Sequential Chromatin Structural Changes at the Activated IL-2 Promoter

S. Ishihara, R. Schwartz, 2011, The Journal of Immunology.

Egr-2 and Egr-3 are negative regulators of T cell activation

Jeanne Kowalski, Amanda Blackford, M. Horton, 2005, Nature Immunology.

Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process

Ronald H. Schwartz, R. Schwartz, D. Bruniquel, 2003, Nature Immunology.

A Distinct Region of the Murine IFN-γ Promoter Is Hypomethylated from Early T Cell Development through Mature Naive and Th1 Cell Differentiation, but Is Hypermethylated in Th2 Cells

R. Schwartz, D. Bruniquel, Benjamin R. Winders, 2004, The Journal of Immunology.

Expression of genes of the T-cell antigen receptor complex in precursor thymocytes

Mark M. Davis, R. Germain, R. Schwartz, 1985, Nature.

Differential expression of two distinct T-cell receptors during thymocyte development

J. Coligan, J. Bluestone, R. Schwartz, 1987, Nature.

Impairment of Immunological Synapse Formation in Adaptively Tolerant T Cells

R. Schwartz, Seeyoung Choi, 2011, The Journal of Immunology.

The -180 site of the IL-2 promoter is the target of CREB/CREM binding in T cell anergy.

R. Schwartz, J. Powell, R H Schwartz, 1999, Journal of immunology.

T lymphocyte-enriched murine peritoneal exudate cells. I. A reliable assay for antigen-induced T lymphocyte proliferation.

W. Paul, R. Schwartz, L. Jackson, 1975, Journal of immunology.

Dual Effects of Sprouty1 on TCR Signaling Depending on the Differentiation State of the T Cell1

R. Schwartz, Kyungho Choi, Heonsik Choi, 2006, The Journal of Immunology.

T cell anergy.

R. Schwartz, 1993, Scientific American.

Antigen-RNA interactions

R. Schwartz, A. A. Gottlieb, 1972 .

Early genetic events in T cell development analyzed by in situ hybridization

R. Germain, R. Lechler, R. Schwartz, 1987, The Journal of experimental medicine.

Adaptive Tolerance and Clonal Anergy Are Distinct Biochemical States1

R. Schwartz, D. Barber, Seeyoung Choi, 2006, The Journal of Immunology.

T‐Cell Unresponsiveness in vivo and in vitro: Fine Specificity of Induction and Molecular Characterization of the Unresponsive State

R. Schwartz, J. Mizuguchi, H. Quill, 1987, Immunological reviews.

Parallel cross-reactivity patterns of 2 sets of antigenically distinct cytochrome c peptides: possible evidence for a presentational model of Ir gene function.

E. Margoliash, E. Appella, R. Schwartz, 1981, Journal of immunology.

Immune response gene control of determinant selection. II. Genetic control of the murine T lymphocyte proliferative response to insulin.

R. Schwartz, M. Barcinski, L. Rosenwasser, 1979, Journal of immunology.

A subset of CD4+ thymocytes selected by MHC class I molecules.

R. Schwartz, D. Littman, N. Killeen, 1994, Science.

The specificity of the syngeneic mixed leukocyte response, a primary anti-I region T cell proliferative response, is determined intrathymically.

D. Longo, R. Schwartz, A. Singer, 1982, Journal of immunology.

IL-2 Secretion by CD4+ T Cells In Vivo Is Rapid, Transient, and Influenced by TCR-Specific Competition

Ronald H. Schwartz, R. Schwartz, D. Bruniquel, 2004, The Journal of Immunology.

The Ia molecule of the antigen-presenting cell plays a critical role in immune response gene regulation of T cell activation.

R. Schwartz, E. Heber-Katz, E Heber-Katz, 1983, The Journal of molecular and cellular immunology : JMCI.

Gene complementation in the T lymphocyte proliferative response to poly (Glu57Lys38Tyr5): evidence for effects of polymer handling and gene dosage.

R. Schwartz, P. Maurer, C. Merryman, 1979, Journal of immunology.

T and B cells that recognize the same antigen do not transcribe similar heavy chain variable region gene segments

L. Hood, R. Schwartz, L. Samelson, 1983, The Journal of experimental medicine.

The immune response to staphylococcal nuclease: a probe of cellular and humoral antigen-specific receptors.

A. Schechter, J. Berzofsky, D. Pisetsky, 1977, Cold Spring Harbor symposia on quantitative biology.

Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody.

R. Schwartz, M. Jenkins, D. Mueller, 1990, Journal of immunology.

Constitutive production of colony-stimulating factor by mouse lymphoma cell lines is correlated with granulocytosis in vivo.

R. Schwartz, D. Monner, 1986, Experimental hematology.

Thymic skewing of the CD4/CD8 ratio maps with the T-cell receptor alpha-chain locus.

R. Schwartz, D. Lo, N. Gascoigne, 1998, Current biology : CB.

A new fractionation assay, based on the size of formaldehyde-crosslinked, mildly sheared chromatin, delineates the chromatin structure at promoter regions

S. Ishihara, R. Schwartz, R. Varma, 2010, Nucleic acids research.

AUGMENTED ANTIBODY‐DEPENDENT CELL‐MEDIATED CYTOTOXICITY FOLLOWING SENSITIZATION OR NONSPECIFIC STIMULATION OF HUMAN EFFECTOR CELLS

R. Schwartz, J. Wunderlich, J. Connolly, 1975, Transplantation.

CD28-Mediated regulation of mRNA stability requires sequences within the coding region of the IL-2 mRNA.

R. Schwartz, J. Ragheb, M. Deen, 1999, Journal of immunology.

Coding Region of the IL-2 mRNA Stability Requires Sequences Within the CD28-Mediated Regulation of mRNA

R. Schwartz, J. Ragheb, M. Deen, 1999 .

Molecular regulation of interleukin‐2 expression by CD28 co‐stimulation and anergy

R. Schwartz, J. Powell, J. Ragheb, 1998, Immunological reviews.

Effect of gamma radiation on resting B lymphocytes. II. Functional characterization of the antigen-presentation defect.

R. Schwartz, M. Jenkins, J. Ashwell, 1988, Journal of immunology.

Anergy and Cytokine-Mediated Suppression as Distinct Superantigen-Induced Tolerance Mechanisms in Vivo

R. Schwartz, J. Ragheb, Carla K. Miller, 1999, The Journal of experimental medicine.

Distinct Effects of TGF-β1 on CD4+ and CD8+ T Cell Survival, Division, and IL-2 Production: A Role for T Cell Intrinsic Smad3

R. Schwartz, S. McKarns, 2005, Journal of Immunology.

Smad3 Is Essential for TGF-β1 to Suppress IL-2 Production and TCR-Induced Proliferation, but Not IL-2-Induced Proliferation1

R. Schwartz, N. Kaminski, S. McKarns, 2004, The Journal of Immunology.

Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferative nonresponsiveness.

R. Schwartz, H. Quill, 1987, Journal of immunology.

High frequency and nonrandom distribution of alloreactivity in T cell clones selected for recognition of foreign antigen in association with self class II molecules.

R. Schwartz, J. Ashwell, C. Chen, 1986, Journal of immunology.

Induction of T cell anergy: integration of environmental cues and infectious tolerance.

R. Schwartz, P. Chappert, Pascal Chappert, 2010, Current opinion in immunology.

Historical overview of immunological tolerance.

R. Schwartz, 2012, Cold Spring Harbor perspectives in biology.

The T lymphocyte response to cytochrome c. V. Determination of the minimal peptide size required for stimulation of T cell clones and assessment of the contribution of each residue beyond this size to antigenic potency.

R. Schwartz, R H Schwartz, C Chen, 1985, Journal of immunology.

Not IL-2-Induced IL-2 Production and TCR-Induced 1 to Suppress β Smad 3 Is Essential for TGF-Kaminski

R. Schwartz, N. Kaminski, S. McKarns, 2004 .

Disease The Immunogenetic Architecture of Autoimmune An Goris and Adrian Liston Self-Control ? Natural Killer Cell Tolerance : Control by Self or

Baptiste N. Jaeger, C. Benoist, R. Locksley, 2012 .

Transactivation by AP-1 Is a Molecular Target of T Cell Clonal Anergy

K. Brorson, R. Schwartz, Sang-Mo Kang, 1992, Science.

Induction of competence to respond to IL-4 by CD4+ T helper type 1 cells requires costimulation.

R. Schwartz, L. Chiodetti, 1992, Journal of immunology.

Costimulatory Interactions Determine Proliferation Versus Induction of Clonal Anergy During Type I CD4 + T-Cell Stimulation

R. Schwartz, M. Jenkins, D. Mueller, 1989 .

Characterization of T cell receptor gamma chain expression in a subset of murine thymocytes.

J. Coligan, R. Germain, J. Bluestone, 1986, Science.

Hypermethylated in Th 2 Cells Th 1 Cell Differentiation , but Is Cell Development through Mature Naive and Promoter Is Hypomethylated from Early T γ A Distinct Region of the Murine IFN-Bruniquel

R. Schwartz, Benjamin R. Winders, 2004 .

The Impact of T Cell Intrinsic Antigen Adaptation on Peripheral Immune Tolerance

R. Schwartz, Nevil J Singh, Chuan Chen, 2006, PLoS biology.

Biallelic expression of the IL‐2 locus under optimal stimulation conditions

R. Schwartz, D. Barber, L. Chiodetti, 2000 .

TCR engagement in the absence of cell cycle progression leads to T cell anergy independent of p27Kip1

R. Schwartz, J. Powell, D. Bruniquel, 2001, European journal of immunology.

Biphasic Regulation of Il2 Transcription in CD4+ T Cells: Roles for TNF-α Receptor Signaling and Chromatin Structure1

R. Schwartz, S. McKarns, 2008, The Journal of Immunology.

Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation.

R. Schwartz, J. Powell, Cara G. Lerner, 1999, Journal of immunology.

Reversal of in vitro T cell clonal anergy by IL-2 stimulation.

R. Schwartz, M. Lenardo, S. Kang, 1992, International immunology.

The pigeon cytochrome c-specific T cell response of low responder mice. I. Identification of antigenic determinants on fragment 1 to 65.

R. Schwartz, G. Suzuki, 1986, Journal of immunology.

TLR Ligands Differentially Modulate T Cell Responses to Acute and Chronic Antigen Presentation1

R. Schwartz, Nevil J. Singh, M. Cox, 2007, The Journal of Immunology.

TLR Ligands Differentially Modulate T Cell

R. Schwartz, Nevil J. Singh, M. Cox, 2007 .

Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid.

R. Germain, R. Schwartz, L. Samelson, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Corrigendum: Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

L. Aravind, R. Schwartz, C. Goodnow, 2010, Nature Immunology.

Molecular mechanisms for adaptive tolerance and other T cell anergy models.

R. Schwartz, Seeyoung Choi, 2007, Seminars in immunology.

Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones.

R. Schwartz, D. Pardoll, M. Jenkins, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Distinct Requirements for C-C Chemokine and IL-2 Production by Naive, Previously Activated, and Anergic T Cells

M. Horton, R. Schwartz, J. Powell, 2000, The Journal of Immunology.

IR GENE COMPLEMENTATION IN THE MURINE T-LYMPHOCYTE PROLIFERATIVE RESPONSE

E. Margoliash, W. Paul, R. Schwartz, 1979 .

Clonal anergy blocks the response to IL-4, as well as the production of IL-2, in dual-producing T helper cell clones.

R. Schwartz, D. Mueller, P. Bacon, 1991, Journal of immunology.

CTLA-4 Engagement Acts as a Brake on CD4+ T Cell Proliferation and Cytokine Production but Is Not Required for Tuning T Cell Reactivity in Adaptive Tolerance

R. Schwartz, M. Inobe, 2004, The Journal of Immunology.

T Lymphocyte-Enriched Murine Peritoneal Exudate Cells

W. Paul, R. Schwartz, D. Sachs, 1975, The Journal of Immunology.

Density dependent re-tuning of autoreactive T cells alleviates their pathogenicity in a lymphopenic environment.

R. Schwartz, Nevil J. Singh, M. Jung, 2017, Immunology letters.

Genetic control of the T lymphocyte proliferative response to staphylococcal nuclease: evidence for multiple MHC-linked Ir gene control.

A. Schechter, J. Berzofsky, R. Schwartz, 1978, Journal of immunology.

CD4+ and CD8+ T cells acquire specific lymphokine secretion potentials during thymic maturation

R. Schwartz, A. Bendelac, 1991, Nature.

Molecular Regulation of the IL‐2 Gene: Rheostatic Control of the Immune System

K. Brorson, R. Schwartz, Sang-mo Kang, 1993, Immunological reviews.

An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness.

R. Schwartz, M. Jenkins, D. Mueller, 1989, Journal of immunology.

The major B and T cell determinant on pigeon cytochrome c in B10.a mice.

E. Margoliash, R. Schwartz, L. Matis, 1982, Advances in experimental medicine and biology.

Epithelial Cell-Specific Laminin 5 Is Required for Survival of Early Thymocytes1

R. Schwartz, J. Yim, Suk-Keun Lee, 2000, The Journal of Immunology.

Erratum: Egr-2 and Egr-3 are negative regulators of T cell activation

M. Horton, C. Drake, R. Schwartz, 2005, Nature Immunology.

The T cell response to allelic determinants on Igh-1-encoded IgG2a antibodies: dual recognition examined by using antigenic antibodies with binding affinity for Ia molecules.

R. Schwartz, S. Hedrick, 1983, Journal of immunology.

EXPRESSION OF Ia ANTIGENS ON T CELL LEUKEMIAS AND THYMOCYTES

R. Schwartz, S. Cullen, K. Okuda, 1978 .

A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family.

J. Coligan, R. Schwartz, D. Pardoll, 1987, Nature.

The Strength of Persistent Antigenic Stimulation Modulates Adaptive Tolerance in Peripheral CD4+ T Cells

R. Schwartz, Nevil J. Singh, 2003, The Journal of experimental medicine.

Analysis of responder cell-cell interactions in the syngeneic mixed leukocyte response.

R. Schwartz, L. Glimcher, 1985, Cellular immunology.

The T lymphocyte response to cytochrome c. IV. Distinguishable sites on a peptide antigen which affect antigenic strength and memory.

E. Appella, R. Schwartz, T Fairwell, 1983, Journal of immunology.

W. Paul, R. Schwartz, G. Cudkowicz, 1979, The Journal of experimental medicine.

THE NATURE OF ANTIGEN‐RIBONUCLEOPROTEIN COMPLEXES

R. Schwartz, S. Waldman, A. A. Gottlieb, 1973, Annals of the New York Academy of Sciences.

Effect of gamma radiation on resting B lymphocytes. I. Oxygen-dependent damage to the plasma membrane results in increased permeability and cell enlargement.

R. Schwartz, J. Ashwell, J. Mitchell, 1986, Journal of immunology.

Ek beta mutant antigen-presenting cell lines expressing altered Ak alpha molecules.

R. Schwartz, L. Glimcher, H. Quill, 1986, Journal of immunology.

BY CHEMICALLY MODIFIED SPLENOCYTES INDUCES ANTIGEN-SPECIFIC T CELL UNRESPONSIVENESS IN VITRO AND IN VIVO

R. Schwartz, M. Jenkins, 2003 .

Associations in T-cell activation.

R. Schwartz, 1985, Nature.

A recovery method for airborne gunshot residue retained in human nasal mucus.

R. Schwartz, C. Zona, 1995, Journal of forensic sciences.

Transcriptional regulation of cytokine genes in nontransformed T cells. Apparent constitutive signals in run-on assays can be caused by repeat sequences.

K. Brorson, R. Schwartz, M. Lenardo, 1991, Journal of immunology.

The effect of antigen presentation on the fine specificity of anti-cytochrome c T cell hybridomas.

R. Schwartz, E. Heber-Katz, D. Hansburg, 1982, Current Topics in Microbiology and Immunology.

Models of T cell anergy: is there a common molecular mechanism?

R. Schwartz, 1996, The Journal of experimental medicine.

GENE COMPLEMENTATION IN THE T-LYMPHOCYTE PROLIFERATION ASSAY: AN ANALYSIS OF THE SITES OF EXPRESSION OF THE TWO GENE PRODUCTS

W. Paul, R. Schwartz, G. Cudkowicz, 1978 .

Antigen presentation by chemically modified splenocytes induces antigen- specific T cell unresponsiveness in vitro and in vivo

R. Schwartz, M. Jenkins, 1987, The Journal of experimental medicine.