N. Savchuk

发表

In silico approaches to prediction of aqueous and DMSO solubility of drug-like compounds: trends, problems and solutions.

I. Tetko, K. Balakin, N. Savchuk, 2006, Current medicinal chemistry.

Bioisosteric morphing in primary hit optimization

K. Balakin, N. Savchuk, Y. Ivanenkov, 2004 .

Modeling of human cytochrome p450-mediated drug metabolism using unsupervised machine learning approach.

Tatiana Nikolskaya, Yuri Nikolsky, Eugene Kirillov, 2003, Journal of medicinal chemistry.

QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES

Sean Ekins, Konstantin V. Balakin, Nikolay P. Savchuk, 2004, Drug Metabolism and Disposition.

KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4

Sean Ekins, Konstantin V. Balakin, Nikolay P. Savchuk, 2004, Drug Metabolism and Disposition.

Comprehensive computational assessment of ADME properties using mapping techniques.

Sean Ekins, Yan A Ivanenkov, Nikolay P Savchuk, 2005, Current drug discovery technologies.

A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling.

Tudor I. Oprea, T. Oprea, N. Savchuk, 2019, Cell chemical biology.

Insights for human ether-a-go-go-related gene potassium channel inhibition using recursive partitioning and Kohonen and Sammon mapping techniques.

Sean Ekins, Yan Ivanenkov, Konstantin V Balakin, 2006, Journal of medicinal chemistry.

Effect of Aprotinin and Avifavir® Combination Therapy for Moderate COVID-19 Patients

N. Savchuk, S. Poyarkov, A. Ivashchenko, 2021, Viruses.

Aprotinin is a potent multi-target drug for the combination therapy of moderate COVID-19 cases

N. Savchuk, S. Poyarkov, A. Ivashchenko, 2020 .

Rational Design of GPCR‐Specific Combinational Libraries Based on the Concept of Privileged Substructures

K. Balakin, N. Savchuk, S. Tkachenko, 2005 .

AVIFAVIR for Treatment of Patients With Moderate Coronavirus Disease 2019 (COVID-19): Interim Results of a Phase II/III Multicenter Randomized Clinical Trial

N. Savchuk, A. Ivashchenko, R. Karapetian, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Interim Results of a Phase II/III Multicenter Randomized Clinical Trial of AVIFAVIR in Hospitalized Patients with COVID-19

N. Savchuk, A. Ivashchenko, R. Karapetian, 2020, medRxiv.

Biochemical profiling of anti-HIV prodrug Elsulfavirine (Elpida®) and its active form VM1500A against a panel of twelve human carbonic anhydrase isoforms

C. Supuran, N. Savchuk, A. Nocentini, 2021, Journal of enzyme inhibition and medicinal chemistry.

Recent progress in discovery and development of antimitotic agents.

K. Balakin, N. Savchuk, S. Tkachenko, 2007, Anti-cancer agents in medicinal chemistry.

Computational mapping tools for drug discovery.

Sean Ekins, Yan A Ivanenkov, Nikolay P Savchuk, 2009, Drug discovery today.

Compound library design for target families.

K V Balakin, Y A Ivanenkov, N P Savchuk, 2009, Methods in molecular biology.

Drug Discovery Using Support Vector Machines. The Case Studies of Drug-likeness, Agrochemical-likeness, and Enzyme Inhibition Predictions

Igor V. Pletnev, Konstantin V. Balakin, Nikolay P. Savchuk, 2003, J. Chem. Inf. Comput. Sci..

In Silico Estimation of DMSO Solubility of Organic Compounds for Bioscreening

Yan A Ivanenkov, Nikolay P Savchuk, Konstantin V Balakin, 2004, Journal of biomolecular screening.

Recent progress in development of non-ATP competitive small-molecule inhibitors of protein kinases.

K. Balakin, N. Savchuk, S. Tkachenko, 2006, Mini-Reviews in Medical Chemistry.

Property-Based Design of GPCR-Targeted Library

Konstantin V. Balakin, Nikolay P. Savchuk, Stanley A. Lang, 2002, J. Chem. Inf. Comput. Sci..

Focused chemistry from annotated libraries

Konstantin V. Balakin, Nikolay P. Savchuk, Sergey E. Tkachenko, 2006 .

New Diversity Calculations Algorithms Used for Compound Selection

Sergei V. Trepalin, Nikolay P. Savchuk, Vadim A. Gerasimenko, 2002, J. Chem. Inf. Comput. Sci..

Exploring the chemogenomic knowledge space with annotated chemical libraries.

Nikolay P Savchuk, Konstantin V Balakin, K. Balakin, 2004, Current opinion in chemical biology.

Rational design approaches to chemical libraries for hit identification.

K. Balakin, N. Savchuk, A. Kiselyov, 2006, Current drug discovery technologies.