L. de las Fuentes

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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

Nicholette D. Palmer, Christine A. Williams, P. Elliott, 2018, PloS one.

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.

Fernando Pires Hartwig, Claude Bouchard, Christian Gieger, 2018, American journal of human genetics.

Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy.

P. Herrero, R. Gropler, L. de las Fuentes, 2002, Journal of the American College of Cardiology.

Nitrate’s Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction Trial: Rationale and Design

Gabriel A. Koepp, K. Anstrom, J. Levine, 2015, Circulation. Heart failure.

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Sebastian M. Armasu, Christine A. Williams, Audrey Y. Chu, 2019, American journal of human genetics.

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Jennifer G. Robinson, Nicholette D. Palmer, Blair H. Smith, 2019, Human molecular genetics.

A Review of the Genetics of Hypertension with a Focus on Gene-Environment Interactions

D. Rao, L. de las Fuentes, R. Waken, 2017, Current Hypertension Reports.

Heart Failure in the Era of Precision Medicine: A Scientific Statement From the American Heart Association.

Carolyn M. Reilly, Ferhaan Ahmad, L. de las Fuentes, 2019, Circulation. Genomic and precision medicine.

Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures.

Sarah M. Hartz, L. Bierut, D. Chasman, 2020, Genetic epidemiology.

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

Nicholette D. Palmer, P. Elliott, M. Fornage, 2019, bioRxiv.

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

Nicholette D. Palmer, Sina A. Gharib, P. Elliott, 2019, Nature Communications.

Relation of left ventricular lead placement in cardiac resynchronization therapy to left ventricular reverse remodeling and to diastolic dyssynchrony.

L. de las Fuentes, M. Faddis, A. Waggoner, 2007, The American journal of cardiology.

Determinants of Diuretic Responsiveness and Associated Outcomes During Acute Heart Failure Hospitalization: An Analysis From the NHLBI Heart Failure Network Clinical Trials.

K. Anstrom, J. Butler, S. Stevens, 2018, Journal of cardiac failure.

Intensification of Medication Therapy for Cardiorenal Syndrome in Acute Decompensated Heart Failure.

K. Anstrom, G. Felker, J. Butler, 2016, Journal of cardiac failure.

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Jennifer G. Robinson, Nicholette D. Palmer, Christine A. Williams, 2019 .

Blunted fat oxidation upon submaximal exercise is partially compensated by enhanced glucose metabolism in children, adolescents, and young adults with Barth syndrome

B. Byrne, R. Wanders, L. de las Fuentes, 2019, Journal of inherited metabolic disease.

Reduced Muscle Strength in Barth Syndrome May Be Improved by Resistance Exercise Training: A Pilot Study.

B. Byrne, L. de las Fuentes, D. Reeds, 2018, JIMD reports.

Clinical outcomes after cardiac resynchronization therapy: importance of left ventricular diastolic function and origin of heart failure.

L. de las Fuentes, M. Faddis, A. Waggoner, 2006, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Role of serotoninergic pathways in drug-induced valvular heart disease and diagnostic features by echocardiography.

L. de las Fuentes, A. Waggoner, V. Dávila-Román, 2009, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Recent Innovations, Modifications, and Evolution of ACC/AHA Clinical Practice Guidelines: An Update for Our Constituencies: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

J. Cigarroa, L. Fleisher, J. Beckman, 2019, Journal of the American College of Cardiology.

J. Cigarroa, L. Fleisher, J. Beckman, 2019, Circulation.

Relation of serum fetuin-A levels to coronary artery calcium in African-American patients on chronic hemodialysis.

A. Bierhals, L. de las Fuentes, J. Delmez, 2009, The American journal of cardiology.

Are normative values for LV geometry and mass based on fundamental imaging valid with use of harmonic imaging?

L. de las Fuentes, A. Waggoner, V. Dávila-Román, 2010, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Alterations in left ventricular structure and function in type-1 diabetics: a focus on left atrial contribution to function.

J. McGill, R. Gropler, K. Schechtman, 2006, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Myocardial Fatty Acid Metabolism: Independent Predictor of Left Ventricular Mass in Hypertensive Heart Disease

P. Herrero, R. Gropler, L. de las Fuentes, 2003, Hypertension.

Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness

J. McGill, K. Yarasheski, K. Schechtman, 2019, Diabetology & Metabolic Syndrome.

Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth.

L. Giudice, L. de las Fuentes, F. de Zegher, 1995, The Journal of clinical endocrinology and metabolism.

Osteopontin promoter polymorphism is associated with increased carotid intima-media thickness.

L. de las Fuentes, A. Waggoner, D. Towler, 2008, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Vitamin D Suppression of Endoplasmic Reticulum Stress Promotes an Antiatherogenic Monocyte/Macrophage Phenotype in Type 2 Diabetic Patients*

K. Schechtman, L. de las Fuentes, L. Bernal-Mizrachi, 2012, The Journal of Biological Chemistry.

Exploring contextual factors influencing the implementation of evidence-based care for hypertension in Rwanda: a cross-sectional study using the COACH questionnaire

K. Schechtman, L. de las Fuentes, D. Reeds, 2021, BMJ Open.

Benefits of the First Pritikin Outpatient Intensive Cardiac Rehabilitation Program

M. Rich, L. de las Fuentes, E. Deych, 2022, Journal of cardiopulmonary rehabilitation and prevention.

Insulin resistance predicts endothelial dysfunction and cardiovascular risk in HIV-infected persons on long-term highly active antiretroviral therapy

K. Yarasheski, L. de las Fuentes, A. Waggoner, 2008, AIDS.

The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions

D. Rao, Y. Sung, K. Schwander, 2019, Human Heredity.

Adiposity and Cardiometabolic Risk in Children With and Without Antipsychotic Drug Treatment.

J. Miller, J. Newcomer, C. Hennekens, 2015, The Journal of clinical endocrinology and metabolism.

Abnormalities in cardiac structure and function in adults with sickle cell disease are not associated with pulmonary hypertension.

L. de las Fuentes, R. Hoffmann, A. Waggoner, 2011, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

The use of bluetooth low energy Beacon systems to estimate indirect personal exposure to household air pollution

K. Balakrishnan, A. Nizam, T. Clasen, 2019, Journal of Exposure Science & Environmental Epidemiology.

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

Dave L Dixon, M. Link, B. Gorenek, 2022, Journal of cardiac failure.

Evaluation of wastewater toxicity: comparative study between Microtox and activated sludge oxygen uptake inhibition.

L. de las Fuentes, J. Etxebarria, M. Gutierrez, 2002, Water research.

A randomized feasibility trial of the Midlife Black Women's Stress and Wellness intervention (B-SWELL); a community participatory intervention to increase adoption of Life's Simple 7 healthy lifestyle behaviors.

T. Bakas, L. de las Fuentes, H. Jones, 2022, Translational behavioral medicine.

A prospective cohort study of the impact of outpatient Intensive Cardiac Rehabilitation on depression and cardiac self-efficacy

M. Rich, L. de las Fuentes, E. Deych, 2022, American heart journal plus : cardiology research and practice.

Metabolic syndrome is associated with abnormal left ventricular diastolic function independent of left ventricular mass.

R. Gropler, L. de las Fuentes, P. Soto, 2006, European heart journal.

Insulin-like growth factor binding proteins in sera of pregnant nonhuman primates.

L. Giudice, L. de las Fuentes, R. Stouffer, 1993, Endocrinology.

Characterization of left ventricular diastolic function in hypertension by use of Doppler tissue imaging and color M-mode techniques.

L. de las Fuentes, A. Waggoner, Nada B. Memon, 2006, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Association and interaction of PPAR-complex gene variants with latent traits of left ventricular diastolic function

C. Gu, L. de las Fuentes, A. Waggoner, 2010, BMC Medical Genetics.

High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study

K. Schechtman, L. de las Fuentes, D. Reeds, 2021, BMC Cardiovascular Disorders.

Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies

Andrew D. Johnson, May E. Montasser, Nicholette D. Palmer, 2022, Nature Genetics.

Baseline associations between household air pollution exposure and blood pressure among pregnant women in the Household Air Pollution Intervention Network (HAPIN) multi-country randomized controlled trial

K. Balakrishnan, T. Clasen, A. Papageorghiou, 2023, medRxiv.

Obesity-insulin targeted genes in the 3p26-25 region in human studies and LG/J and SM/J mice.

J. Cheverud, I. Borecki, A. Kraja, 2012, Metabolism: clinical and experimental.

Effects of Sodium Thiosulfate on Vascular Calcification in End-Stage Renal Disease: A Pilot Study of Feasibility, Safety and Efficacy

A. Bierhals, L. de las Fuentes, J. Delmez, 2011, American Journal of Nephrology.

Single nucleotide polymorphism-single nucleotide polymorphism interactions among inflammation genes in the genetic architecture of blood pressure in the Framingham Heart Study.

L. de las Fuentes, Jacob J Basson, D. Rao, 2015, American journal of hypertension.

Gene-education interactions identify novel blood pressure loci in the Framingham Heart Study.

Yun Ju Sung, Karen Schwander, D. Rao, 2014, American journal of hypertension.

Population sequencing data reveal a compendium of mutational processes in human germline

Ryan D. Hernandez, Nicholette D. Palmer, S. Redline, 2020, bioRxiv.

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Andrew D. Johnson, Benjamin D. Heavner, Ryan D. Hernandez, 2022, Nature Genetics.

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

Jennifer G. Robinson, Nicholette D. Palmer, P. Elliott, 2019, Nature Communications.

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Jennifer G. Robinson, M. P. Concas, Nicholette D. Palmer, 2019, Nature Genetics.

Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed

Ivana V. Yang, Benjamin D. Heavner, Nicholette D. Palmer, 2022, Cell genomics.

Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential

Nicholette D. Palmer, J. Danesh, M. Fornage, 2022, Science advances.

Feitosa, M. F., InterAct Consortium, & Levy, D. (2018). Novel genetic associations for blood pressure identified via gene-alcohol interaction in up

Bamidele, áková, Christine A. Williams, 2018 .

Aggregate blood pressure responses to serial dietary sodium and potassium intervention: defining responses using independent component analysis

T. Rice, D. Gu, D. Rao, 2015, BMC Genetics.

2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Matthew W. Martinez, Michael A. Burke, Dave L Dixon, 2021, The Journal of thoracic and cardiovascular surgery.

2020 ACC/AHA guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Dave L Dixon, B. Gorenek, D. Mark, 2021, The Journal of thoracic and cardiovascular surgery.

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

D. Rao, Y. Sung, K. Schwander, 2015, American journal of hypertension.

Effect of moderate diet-induced weight loss and weight regain on cardiovascular structure and function.

H. Wyatt, L. de las Fuentes, B. S. Mohammed, 2009, Journal of the American College of Cardiology.

LPG stove and fuel intervention among pregnant women reduce fine particle air pollution exposures in three countries: Pilot results from the HAPIN trial

K. Balakrishnan, A. Nizam, T. Clasen, 2021, Environmental pollution.

Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity.

L. de las Fuentes, S. Klein, F. Magkos, 2016, Cell metabolism.

Molecular determinants of the cardiometabolic phenotype.

G. de Simone, D. Arnett, L. de las Fuentes, 2010, Endocrine, metabolic & immune disorders drug targets.

Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium.

Benjamin D. Heavner, Kelsey E. Grinde, A. Reiner, 2021, EBioMedicine.

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

Nicholette D. Palmer, P. Elliott, M. Fornage, 2020, Molecular Psychiatry.

Timing of cardiac transplantation in patients with heart failure receiving beta-adrenergic blockers.

G. Ewald, K. Schechtman, L. de las Fuentes, 2003, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

An overview of the genomics of metabolic syndrome.

A. Kraja, L. de las Fuentes, A. Cashion, 2013, Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing.

Genome-Wide Meta-analysis of Variant-by-Diuretic Interactions as Modulators of Lipid Traits in Persons of European and African Ancestry

A. Reiner, S. Cummings, K. Taylor, 2019, The Pharmacogenomics Journal.

The St. Louis African American health-heart study: methodology for the study of cardiovascular disease and depression in young-old African Americans

R. Carney, P. Stein, T. Burroughs, 2013, BMC Cardiovascular Disorders.

Timing and Causes of Readmission After Acute Heart Failure Hospitalization-Insights From the Heart Failure Network Trials.

L. de las Fuentes, S. Dunlay, A. Lala, 2016, Journal of cardiac failure.

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Jennifer G. Robinson, Nicholette D. Palmer, Christine A. Williams, 2019, Nature Genetics.

Effects of Phosphate Binder Therapy on Vascular Stiffness in Early-Stage Chronic Kidney Disease

A. Bierhals, L. de las Fuentes, K. Hruska, 2013, American Journal of Nephrology.

Dissemination and Implementation Program in Hypertension in Rwanda: Report on Initial Training and Evaluation.

K. Yarasheski, L. de las Fuentes, D. Reeds, 2019, Global heart.

Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions

E. Boerwinkle, L. Cupples, D. Rao, 2021, European Journal of Human Genetics.

Lifestyle Risk Score for aggregating multiple lifestyle factors: Handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions

E. Boerwinkle, L. Cupples, D. Rao, 2020, bioRxiv.

Relationships among HIV infection, metabolic risk factors, and left ventricular structure and function.

K. Yarasheski, L. de las Fuentes, M. Krauss, 2013, AIDS research and human retroviruses.

N-terminal pro B-type natriuretic peptide levels: correlation with echocardiographically determined left ventricular diastolic function in an ambulatory cohort.

G. Ewald, S. Dong, L. de las Fuentes, 2006, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Lung Ultrasound Protocol and Quality Control of Image Interpretation Using an Adjudication Panel in the Household Air Pollution Intervention Network (HAPIN) Trial.

K. Balakrishnan, T. Clasen, A. Papageorghiou, 2023, Ultrasound in medicine & biology.

The role of SNP-loop diuretic interactions in hypertension across ethnic groups in HyperGEN

D. Rao, S. Hunt, D. Arnett, 2013, Front. Genet..

Cardiovascular phenotype in HFpEF patients with or without diabetes: a RELAX trial ancillary study.

L. de las Fuentes, Adrian F. Hernandez, D. Mann, 2014, Journal of the American College of Cardiology.

Williams Syndrome Predisposes to Vascular Stiffness Modified by Antihypertensive Use and Copy Number Changes in NCF1

L. de las Fuentes, R. Knutsen, B. Pober, 2014, Hypertension.

Resistance exercise training with protein supplementation improves skeletal muscle strength and improves quality of life in late adolescents and young adults with Barth syndrome: A pilot study

B. Byrne, L. de las Fuentes, D. Reeds, 2021, JIMD reports.

Impaired cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with Barth syndrome

B. Byrne, L. de las Fuentes, D. Reeds, 2017, Physiological reports.

Clonal haematopoiesis and risk of chronic liver disease

Andrew D. Johnson, Benjamin D. Heavner, May E. Montasser, 2023, Nature.

Role of Nitrate Therapy in HF

Gabriel A. Koepp, K. Anstrom, J. Levine, 2015 .

Genome-Wide Meta-analysis of Variant-by-Diuretic Interactions as Modulators of Lipid Traits in Persons of European and African Ancestry

A. Uitterlinden, A. Reiner, S. Cummings, 2019, The Pharmacogenomics Journal.

Plasma triglyceride level is an independent predictor of altered left ventricular relaxation.

L. de las Fuentes, A. Waggoner, V. Dávila-Román, 2005, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Three Approaches to Modeling Gene‐Environment Interactions in Longitudinal Family Data: Gene‐Smoking Interactions in Blood Pressure

A. Vazquez, Y. Sung, K. Schwander, 2016, Genetic epidemiology.

Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify MYRIP, TRAPPC11, and SLC27A6 of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population

D. Nickerson, Joshua D. Smith, D. Rao, 2021, Frontiers in Genetics.

Left Ventricular Mass Progression despite Stable Blood Pressure and Kidney Function in Stage 3 Chronic Kidney Disease

L. de las Fuentes, K. Hruska, D. Dietzen, 2014, American Journal of Nephrology.

Central aortic pressure is independently associated with diastolic function.

L. de las Fuentes, A. Waggoner, V. Dávila-Román, 2010, American heart journal.

2022 ACC/AHA guideline for the diagnosis and management of aortic disease: A report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.

Dave L Dixon, P. Tsao, B. Gorenek, 2023, The Journal of thoracic and cardiovascular surgery.

Enhanced detection of genetic association of hypertensive heart disease by analysis of latent phenotypes

L. de las Fuentes, V. Dávila-Román, C. Charles Gu, 2008, Genetic epidemiology.

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

Jennifer G. Robinson, Nicholette D. Palmer, P. Elliott, 2019, Nature Communications.

Cardiac resynchronization therapy acutely improves diastolic function.

L. de las Fuentes, A. Waggoner, M. Gleva, 2005, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Research Education and Mentoring Program in Cardiovascular Diseases for Under-Represented Junior Faculty From NHLBI SIPID/PRIDE.

T. Rice, D. Jeffe, J. Jobe, 2019, Journal of the American College of Cardiology.

Interatrial conduction time and left atrial function in patients with left ventricular systolic dysfunction: effects of cardiac resynchronization therapy.

L. de las Fuentes, A. Waggoner, V. Dávila-Román, 2009, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Doppler Echocardiographic Methods for Optimization of the Atrioventricular Delay during Cardiac Resynchronization Therapy

L. de las Fuentes, A. Waggoner, V. Dávila-Román, 2008, Echocardiography.

Genetic association analysis of coronary heart disease by profiling gene-environment interaction based on latent components in longitudinal endophenotypes

A. Kraja, C. Gu, L. de las Fuentes, 2009, BMC proceedings.

Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma

Andrew D. Johnson, Benjamin D. Heavner, May E. Montasser, 2023, EBioMedicine.

Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium

Andrew D. Johnson, Benjamin D. Heavner, May E. Montasser, 2020, Genome Medicine.

A Novel Method Combining Linkage Disequilibrium Information and Imputed Functional Knowledge for tagSNP Selection

G. Stormo, G. Stormo, L. de las Fuentes, 2007, Human Heredity.

Population sequencing data reveal a compendium of mutational processes in human germline

Nicholette D. Palmer, S. Redline, E. Boerwinkle, 2021, Science.