Alun Thomas

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Alternative graphical representations of genotypes in a pedigree

C. Harbron, Alun Thomas, 1994 .

Identification of regions of positive selection using Shared Genomic Segment analysis

Alun Thomas, Lisa Cannon-Albright, N. Camp, 2011, European Journal of Human Genetics.

Tests of association for rare variants: case control mutation screening

S. Tavtigian, Alun Thomas, M. Hashibe, 2011, Nature Reviews Genetics.

W 81 XWH-07-1-0483 TITLE : In Silico Genome Mismatch Scanning to Map Breast Cancer Genes in

Alun Thomas, 2009 .

In Silico Genome Mismatch Scanning to Map Breast Cancer Genes in Extended Pedigrees

Alun Thomas, 2008 .

Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing

G. Marth, D. Nix, M. Bronner, 2018, PloS one.

Characterizing allelic associations from unphased diploid data by graphical modeling

Alun Thomas, Alun Thomas, 2005, Genetic epidemiology.

Effect of linkage disequilibrium on the identification of functional variants

Jin Liu, Alun Thomas, H. Abel, 2011, Genetic epidemiology.

Gene hunting with gradients of likelihoods

Alun Thomas, 1991 .

Resolving the Functional Significance of BRCA1 RING Domain Missense Substitutions

W. Foulkes, S. Tavtigian, Jason Gertz, 2016, bioRxiv.

Increased ProstateCancer Risk

L. Cannon-Albright, N. Agarwal, J. Farnham, 2014 .

Identifying rare variants from exome scans: the GAW17 experience

R. Cantor, N. Laird, I. König, 2011, BMC proceedings.

Comprehensive evaluation and efficient classification of BRCA1 RING domain missense substitutions.

W. Foulkes, S. Tavtigian, Jason Gertz, 2022, American journal of human genetics.

Pathways analysis of differential gene expression induced by engrafting doses of total body irradiation for allogeneic bone marrow transplantation in mice

Alun Thomas, S. Tsai, J. Shizuru, 2013, Immunogenetics.

Identification of a Major Susceptibility Locus for Lethal Graft-versus-Host Disease in MHC-Matched Mice1

N. Camp, L. Lazzeroni, Alun Thomas, 2009, The Journal of Immunology.

Analysis of high-density single-nucleotide polymorphism data: three novel methods that control for linkage disequilibrium between markers in a linkage analysis

B. Horne, N. Camp, Alun Thomas, 2007, BMC proceedings.

Evidence for Linkage on Chromosome 3q25–27 in a Large Autism Extended Pedigree

W. McMahon, H. Coon, Judith S Miller, 2006, Human Heredity.

Replication of the 10q11 and Xp11 Prostate Cancer Risk Variants: Results from a Utah Pedigree-Based Study

N. Camp, L. Cannon-Albright, J. Farnham, 2009, Cancer Epidemiology Biomarkers & Prevention.

Linkage analysis of extended high-risk pedigrees replicates a cutaneous malignant melanoma predisposition locus on chromosome 9q21

L. Cannon-Albright, J. Farnham, Alun Thomas, 2012, The Journal of investigative dermatology.

Population‐based risk assessment for other cancers in relatives of hereditary prostate cancer (HPC) cases

N. Camp, Jim Farnham, Alun Thomas, 2005, The Prostate.

Pathways analysis of differential gene expression induced by engrafting doses of total body irradiation for allogeneic bone marrow transplantation in mice

Alun Thomas, S. Tsai, J. Shizuru, 2013, Immunogenetics.

A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q

N. Camp, L. Cannon-Albright, J. Farnham, 2011, Human Genetics.

Fine mapping of the Bmgr5 quantitative trait locus for allogeneic bone marrow engraftment in mice

Alun Thomas, S. Tsai, J. Shizuru, 2013, Immunogenetics.

Calibration of Multiple In Silico Tools for Predicting Pathogenicity of Mismatch Repair Gene Missense Substitutions

Predrag Radivojac, Biao Li, Alun Thomas, 2013, Human mutation.

A chromosome 16 quantitative trait locus regulates allogeneic bone marrow engraftment in nonmyeloablated mice.

Alun Thomas, S. Tsai, J. Shizuru, 2009, Blood.

MHC-Matched Mice for Lethal Graft-versus-Host Disease in Identification of a Major Susceptibility Locus

N. Camp, L. Lazzeroni, Alun Thomas, 2009 .

Shared Genomic Segment Analysis: The Power to Find Rare Disease Variants

Stacey Knight, Alun Thomas, Randall W Burt, 2012, Annals of human genetics.

Pairwise shared genomic segment analysis in high-risk pedigrees: application to Genetic Analysis Workshop 17 exome-sequencing SNP data

N. Camp, Alun Thomas, Zheng Cai, 2011, BMC proceedings.

A candidate prostate cancer susceptibility gene at chromosome 17p

Siavash Ghaffari, Alun Thomas, Nicola J. Camp, 2001, Nature Genetics.

Random allelic expression in the adult human body

A. Quinlan, M. Love, Alun Thomas, 2023, Cell reports.

Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study

J. Hopper, E. John, M. Southey, 2011, Breast Cancer Research.

Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer.

Alun Thomas, Sue Healey, John L Hopper, 2009, American journal of human genetics.

Classification of rare missense substitutions, using risk surfaces, with genetic‐ and molecular‐epidemiology applications

Alun Thomas, Sean V Tavtigian, S. Tavtigian, 2008, Human mutation.

An Analysis of Unclassified Missense Substitutions in Human BRCA1

S. Tavtigian, Alun Thomas, P. Samollow, 2005, Familial Cancer.

Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21

D. Schaid, R. Eeles, Z. Kote-Jarai, 2016, Human Genetics.

Cancer Risk in Families Fulfilling the Amsterdam Criteria for Lynch Syndrome

Ken R. Smith, L. Cannon-Albright, Alun Thomas, 2017, JAMA oncology.

Familial Associations between Cancer Sites

Alun Thomas, Aruna Bansal, Lisa Cannon-Albright, 1999, Comput. Biomed. Res..

A Nonsynonymous Variant in the GOLM1 Gene in Cutaneous Malignant Melanoma

L. Cannon-Albright, J. Farnham, Alun Thomas, 2018, Journal of the National Cancer Institute.

Towards Linkage Analysis with Markers in Linkage Disequilibrium by Graphical Modelling

Alun Thomas, Alun Thomas, 2007, Human Heredity.

A parallel genetic algorithm to discover patterns in genetic markers that indicate predisposition to multifactorial disease

Julio C. Facelli, Alun Thomas, Nicola J. Camp, 2008, Comput. Biol. Medicine.

Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk

H. Coon, N. Camp, C. Vachon, 2017, bioRxiv.

A New Nonparametric Linkage Statistic for Mapping Both Qualitative and Quantitative Trait Loci

N. Camp, L. Cannon-Albright, A. Gutin, 2001, Genetic epidemiology.

Graphical modeling of the joint distribution of alleles at associated loci.

N. Camp, Alun Thomas, 2004, American journal of human genetics.

Characterization of linkage disequilibrium structure, mutation history, and tagging SNPs, and their use in association analyses: ELAC2 and familial early‐onset prostate cancer

B. Horne, N. Camp, L. Cannon-Albright, 2005, Genetic epidemiology.

Extracting disease risk profiles from expression data for linkage analysis: application to prostate cancer

N. Camp, L. Cannon-Albright, Alun Thomas, 2007, BMC proceedings.

Evaluation of record linkage between a large healthcare provider and the Utah Population Database

Scott L. DuVall, Alun Thomas, Kerry Rowe, 2012, J. Am. Medical Informatics Assoc..

Identification of specific Y chromosomes associated with increased prostate cancer risk

L. Cannon-Albright, N. Agarwal, J. Farnham, 2014, The Prostate.

Pairwise shared genomic segment analysis in three Utah high-risk breast cancer pedigrees

N. Camp, L. Cannon-Albright, J. Farnham, 2012, BMC Genomics.

Efficient parameter estimation for models of healthcare-associated pathogen transmission in discrete and continuous time.

Andrew Redd, Alun Thomas, Matthew Samore, 2015, Mathematical medicine and biology : a journal of the IMA.

Population genealogy resource shows evidence of familial clustering for Alzheimer disease

Sue M. Dintelman, L. Cannon-Albright, J. Kauwe, 2018, Neurology: Genetics.

Detection of circulating tumor DNA without a tumor-informed search using next-generation sequencing is a prognostic biomarker in pancreatic ductal adenocarcinoma

D. Nix, M. Bronner, Alun Thomas, 2021, Neoplasia.

An Application of the Latent p Value Method to Assess Linkage in Asthma Pedigrees

Alun Thomas, C. Teerlink, 2010, Human Heredity.

Reparameterization of PAM50 Expression Identifies Novel Breast Tumor Dimensions and Leads to Discovery of a Genome-Wide Significant Breast Cancer Locus at 12q15

N. Camp, I. Stijleman, P. Bernard, 2018, Cancer Epidemiology, Biomarkers & Prevention.

Reparameterization of PAM50 expression identifies novel breast tumor dimensions and leads to discovery of a breast cancer susceptibility locus at 12q15

N. Camp, P. Bernard, Alun Thomas, 2017, bioRxiv.

Reparameterization of PAM50 expression identifies novel breast tumor dimensions and leads to discovery of a breast cancer susceptibility locus at 12q15

N. Camp, P. Bernard, Alun Thomas, 2017, bioRxiv.

Identification of Novel Breast Tumor Expression Dimensions within the PAM50 and Discovery of a Breast Cancer Susceptibility Locus at 12q15

N. Camp, P. Bernard, Alun Thomas, 2017 .

Reparameterization of PAM 50 expression identifies novel breast tumor dimensions and leads to discovery of a breast cancer susceptibility locus at 12 q 15

N. Camp, P. Bernard, Alun Thomas, 2017 .

Creation of a national resource with linked genealogy and phenotypic data: the Veterans Genealogy Project

Sue M. Dintelman, L. Cannon-Albright, Alun Thomas, 2013, Genetics in Medicine.

Detecting Pleiotropy and Epistasis Using Variance Components Linkage Analysis in jPAP

Alun Thomas, Sandy Hasstedt, 2011, Human Heredity.

Extending the Fellegi-Sunter probabilistic record linkage method for approximate field comparators

Scott L. DuVall, Alun Thomas, Richard A. Kerber, 2010, J. Biomed. Informatics.

A method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci, and their application to gene drop simulation

Alun Thomas, Alun Thomas, 2009, Bioinform..

Statistical Applications in Genetics and Molecular Biology Accuracy and Computational Efficiency of a Graphical Modeling Approach to Linkage Disequilibrium Estimation

Haley J. Abel, Alun Thomas, Alun Thomas, 2011 .

A note on the four-colourability of pedigrees and its consequences for probability calculations

Alun Thomas, Alun Thomas, 1993 .

Comprehensive statistical study of 452 BRCA1 missense substitutions with classification of eight recurrent substitutions as neutral

A. Zharkikh, S. Tavtigian, Alun Thomas, 2005, Journal of Medical Genetics.

Comparison of an exact and a simulation method for calculating gene extinction probabilities in pedigrees

Alun Thomas, 1990 .

Novel pedigree analysis implicates DNA repair and chromatin 1 remodeling in Multiple Myeloma risk 2

H. Coon, N. Camp, C. Vachon, 2017 .

Employing MCMC under the PPL framework to analyze sequence data in large pedigrees

Yungui Huang, Veronica J. Vieland, Alun Thomas, 2013, Front. Genet..

Maximum likelihood estimates of allele frequencies and error rates from samples of related individuals by gene counting

Alun Thomas, Nicola J. Camp, N. Camp, 2006, Bioinform..

A Laboratory Information Management System (LIMS) for a high throughput genetic platform aimed at candidate gene mutation screening

Alun Thomas, Catherine Voegele, Sean V. Tavtigian, 2007, Bioinform..

A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q

N. Camp, L. Cannon-Albright, J. Farnham, 2011, Human Genetics.

Accelerated Gene Counting for Haplotype Frequency Estimation

Alun Thomas, Alun Thomas, 2003, Annals of human genetics.

GCHap: fast MLEs for haplotype frequencies by gene counting

Alun Thomas, Alun Thomas, 2003, Bioinform..

GMCheck: Bayesian error checking for pedigreegenotypes and phenotypes

Alun Thomas, Alun Thomas, 2005, Bioinform..

Extracting disease risk profiles from expression data for linkage analysis: application to prostate cancer

V. Vieland, N. Camp, L. Almasy, 2007, BMC proceedings.

Reframing Breast Cancer Molecular Subtypes: Modeling Expression Patterns with Orthogonal Dimensions

P. Bernard, Alun Thomas, M. Salama, 2017 .

Calibration of Multiple In Silico Tools for Predicting Pathogenicity of Mismatch Repair Gene Missense Substitutions

P. Radivojac, S. Mooney, S. Sunyaev, 2013, Human mutation.

Haplotype association analyses in resources of mixed structure using Monte Carlo testing

Ryan Abo, Alun Thomas, Nicola J. Camp, 2010, BMC Bioinformatics.