B. J. Barratt

发表

Genome-wide association studies: theoretical and practical concerns

D. Clayton, J. Todd, William Y S Wang, 2005, Nature Reviews Genetics.

Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design.

D. Clayton, J. Todd, S. Nutland, 2002, Annals of human genetics.

IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity

E. Bonifacio, J. Todd, B. J. Barratt, 2003, Diabetologia.

Haplotype tagging for the identification of common disease genes

Frank Dudbridge, John A. Todd, Heather J. Cordell, 2001, Nature Genetics.

SNP allele frequency estimation in DNA pools and variance components analysis.

Panos Deloukas, Pelin Akan, Kate Downes, 2004, BioTechniques.

Tacrine-induced liver damage: an analysis of 19 candidate genes

M. Pirmohamed, B. J. Barratt, D. Carr, 2007, Pharmacogenetics and genomics.

Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, gene‐gene and gene‐environment interactions, and parent‐of‐origin effects

Heather J Cordell, D. Clayton, H. Cordell, 2004, Genetic epidemiology.

Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation.

J. Todd, S. Nutland, H. Stevens, 2000, Genome research.

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.

Adrian Vella, Cristian Guja, Susan M Ring, 2004, Diabetes.

Remapping the insulin gene/IDDM2 locus in type 1 diabetes.

Mark I McCarthy, Heather J Cordell, Jaakko Tuomilehto, 2004, Diabetes.

Maternal-fetal interactions and birth order influence insulin variable number of tandem repeats allele class associations with head size at birth and childhood weight gain.

J. Todd, S. Ring, M. Pembrey, 2004, Diabetes.

Haplotype tag single nucleotide polymorphism analysis of the human orthologues of the rat type 1 diabetes genes Ian4 (Lyp/Iddm1) and Cblb.

J. Todd, S. Nutland, N. Walker, 2004, Diabetes.

Comparison of population‐ and family‐based methods for genetic association analysis in the presence of interacting loci

J. Todd, H. Cordell, J. Howson, 2005, Genetic epidemiology.

Lack of Association of the Ala45Thr Polymorphism and Other Common Variants of the NeuroD Gene With Type 1 Diabetes

J. Todd, S. Nutland, J. Tuomilehto, 2004 .

Genetic Determinants of Statin-Induced Low-Density Lipoprotein Cholesterol Reduction: The Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) Trial

P. Ridker, D. Chasman, B. J. Barratt, 2012, Circulation. Cardiovascular genetics.

Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster

M. Pirmohamed, D. Chadwick, B. J. Barratt, 2006, Pharmacogenetics and genomics.

Brief Genetics Report Lack of Association of the Ala 45 Thr Polymorphism and Other Common Variants of the NeuroD Gene With Type 1 Diabetes

J. Todd, S. Nutland, J. Tuomilehto, 2004 .

Lack of association of the Ala(45)Thr polymorphism and other common variants of the NeuroD gene with type 1 diabetes.

J. Todd, S. Nutland, J. Tuomilehto, 2004, Diabetes.

Analysis of the type 2 diabetes-associated single nucleotide polymorphisms in the genes IRS1, KCNJ11, and PPARG2 in type 1 diabetes.

J. Todd, N. Walker, J. Tuomilehto, 2004, Diabetes.

NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes: Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO)

E. Hagström, N. Eriksson, A. Syvänen, 2015, Circulation. Cardiovascular genetics.

Are There Any Causal Relations Between Growth Differentiation Factor 15 and Outcomes in Patients With Acute Coronary Syndrome? : - A Report From the Plato Gwas Study

E. Hagström, N. Eriksson, A. Syvänen, 2013 .

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

Joshua C Denny, Wei-Qi Wei, Fredrik Nyberg, 2016, Journal of Medical Genetics.

Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis

A Jawaid, E M Brown, L R Cardon, 2008, The Pharmacogenomics Journal.

Optimizing the Power of Genome-Wide Association Studies by Using Publicly Available Reference Samples to Expand the Control Group

Fredrik Nyberg, Andrew P Morris, Ansar Jawaid, 2010, Genetic epidemiology.

Sequencing and association analysis of the type 1 diabetes – linked region on chromosome 10p12-q11

J. Rogers, J. Todd, S. Nutland, 2007, BMC Genetics.

Association analysis of the lymphocyte-specific protein tyrosine kinase (LCK) gene in type 1 diabetes.

J. Todd, J. Tuomilehto, J. Howson, 2004, Diabetes.

Cost-effective analysis of candidate genes using htSNPs: a staged approach

J Tuomilehto, D G Clayton, D. Clayton, 2004, Genes and Immunity.

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

Matti Pirinen, David M. Herrington, Alex Doney, 2014, Nature Communications.

Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial

B. J. Barratt, L. Wallentin, R. Becker, 2010, The Lancet.

Molecular and genetic association of interleukin-6 in tacrine-induced hepatotoxicity

M. Pirmohamed, B. J. Barratt, B. Kevin Park, 2007, Pharmacogenetics and genomics.

Optimising the power of genome-wide association studies by using publicly available reference samples to expand the controls group

Lon R. Cardon, Krina T. Zondervan, Andrew P. Morris, 2009 .

Development of an integrated genome informatics, data management and workflow infrastructure: A toolbox for the study of complex disease genetics

Helen Schuilenburg, Vincent H. Everett, Neil M Walker, 2004, Human Genomics.

Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans

J. Todd, S. Ring, M. Pembrey, 2005, BMC Genetics.

Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.

D. Voora, E. Hagström, N. Eriksson, 2015, European heart journal.

Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome.

N. Eriksson, A. Syvänen, B. J. Barratt, 2016, Human molecular genetics.

Differential Genetic Effects on Statin-Induced Changes Across Low-Density Lipoprotein–Related Measures

Audrey Y. Chu, P. Ridker, D. Chasman, 2015, Circulation. Cardiovascular genetics.

Lack of association between SLCO1B1 polymorphisms and clinical myalgia following rosuvastatin therapy.

P. Ridker, D. Chasman, B. J. Barratt, 2013, American heart journal.

Genome-Wide Association Study Evaluating Lipoprotein-Associated Phospholipase A2 Mass and Activity at Baseline and After Rosuvastatin Therapy

Fredrik Nyberg, Josée Dupuis, Harald Grallert, 2012, Circulation. Cardiovascular genetics.

Pharmacogenetic Determinants of Statin-Induced Reductions in C-Reactive Protein

Audrey Y. Chu, P. Ridker, D. Chasman, 2012, Circulation. Cardiovascular genetics.

Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.

Yusuke Nakamura, H. Kato, S. Kudoh, 2011, Pharmacogenomics.

Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study.

N. Eriksson, A. Budaj, B. J. Barratt, 2014, American Heart Journal.

BMC Biotechnology BioMed Central Methodology article A gene expression system offering multiple levels of regulation: the Dual Drug Control (DDC) system

J. Todd, S. Nutland, N. Walker, 2004 .

TICAGRELOR PLASMA LEVELS BUT NOT CLINICAL OUTCOMES ARE ASSOCIATED WITH TRANSPORTER AND METABOLISM ENZYME GENETIC POLYMORPHISMS

D. Voora, E. Hagström, N. Eriksson, 2014 .

Gene mapping strategies for complex disease and drug response.

B. J. Barratt, R. March, A. Jawaid, 2006, Drug discovery today. Technologies.

Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome.

N. Eriksson, A. Syvänen, B. J. Barratt, 2016, Human molecular genetics.

Investigating the utility of combining Φ29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray™ genotyping

S. Nutland, N. Walker, D. Smyth, 2004, BMC biotechnology.

Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design

D. Clayton, J. Todd, S. Nutland, 2002 .

Investigating the utility of combining Φ29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray™ genotyping

S. Nutland, N. Walker, D. Smyth, 2004, BMC Biotechnology.