R. Lazarus

发表

Instrumenting the health care enterprise for discovery research in the genomic era.

I. Kohane, H. Chueh, J. Glaser, 2009, Genome research.

Clues: an R Package for Nonparametric Clustering Based on Local Shrinking

Xiaogang Wang, Ruben H. Zamar, Weiliang Qiu, 2022 .

Galaxy: A Web‐Based Genome Analysis Tool for Experimentalists

Daniel J. Blankenberg, Mary E. Mangan, James Taylor, 2010, Current protocols in molecular biology.

Genetic adaptation of the antibacterial human innate immunity network

M. Netea, P. Awadalla, J. Bertranpetit, 2011, BMC Evolutionary Biology.

An integrative systems genetic analysis of mammalian lipid metabolism

D. James, P. Meikle, R. Lazarus, 2019, Nature.

On the replication of genetic associations: timing can be everything!

F. Kronenberg, D. Levy, U. Thorsteinsdóttir, 2008, American journal of human genetics.

the genomic era Instrumenting the health care enterprise for discovery research in

I. Kohane, H. Chueh, J. Glaser, 2009 .

A Marginal Mixture Model for Selecting Differentially Expressed Genes across Two Types of Tissue Samples

Xiaogang Wang, Wenqing He, R. Lazarus, 2008, The international journal of biostatistics.

Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes

J. Celedón, A. Litonjua, R. Lazarus, 2011, BMC Medical Genetics.

FCER2: a pharmacogenetic basis for severe exacerbations in children with asthma.

J. Xu, S. Weiss, T. Mariani, 2007, The Journal of allergy and clinical immunology.

Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma

J. Xu, S. Weiss, A. Litonjua, 2008, Pharmacogenetics and genomics.

Identification of 54 large deletions/duplications in TSC1 and TSC2 using MLPA, and genotype-phenotype correlations

R. Lazarus, D. Kwiatkowski, J. Bissler, 2007, Human Genetics.

Genetic association analysis of functional impairment in chronic obstructive pulmonary disease.

D. DeMeo, B. Make, E. Silverman, 2006, American journal of respiratory and critical care medicine.

Lung function in type 2 diabetes: the Normative Aging Study.

S. Weiss, A. Litonjua, R. Lazarus, 2005, Respiratory medicine.

Package 'geneselectmmd'

R. Lazarus, remdj, stwxq, 2013 .

IgG subclass specific antibody response to periodontopathic organisms in HIV-positive patients.

R. Lazarus, G. Seymour, C. Daly, 2002, Journal of periodontology.

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

Ingo Ruczinski, Christoph Lange, James W Baurley, 2009, American journal of human genetics.

Genomic screening in family-based association testing

N. Laird, K. Van Steen, P. Kraft, 2005, BMC Genetics.

remodelingexercise: from inflammation to adaptive of human skeletal muscle during recovery from Time course-dependent changes in the transcriptome

A. Bulmer, R. Lazarus, M. Peake, 2015 .

Time course-dependent changes in the transcriptome of human skeletal muscle during recovery from endurance exercise: from inflammation to adaptive remodeling.

A. Bulmer, R. Lazarus, D. Cameron-Smith, 2014, Journal of applied physiology.

damagecytokines, neutrophil dynamics, and muscle Endurance exercise causes interaction among stress

M. Martorell, A. Sureda, R. Lazarus, 2015 .

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update

Christopher B. Barnett, Daniel J. Blankenberg, Ralf J. M. Weber, 2022, Nucleic Acids Res..

Genetic determinants of functional impairment in chronic obstructive pulmonary disease.

D. DeMeo, E. Silverman, J. Celedón, 2006, Proceedings of the American Thoracic Society.

moderate- and high-intensity exercise degranulation, and respiratory burst activity after Changes in neutrophil surface receptor expression,

R. Lazarus, Katsuhiko Suzuki, Oliver Neubauer, 2015 .

Late-breaking abstract: Genome-wide association of GLCCI1 with asthma steroid treatment response

Yusuke Nakamura, A. Litonjua, W. Qiu, 2011 .

Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.

Yusuke Nakamura, A. Litonjua, W. Qiu, 2011, The New England journal of medicine.

Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program.

N. Laird, E. Silverman, J. Drazen, 2003, The Journal of allergy and clinical immunology.

Association of vitamin D receptor gene polymorphisms with childhood and adult asthma.

E. Silverman, C. Lange, R. Lazarus, 2004, American journal of respiratory and critical care medicine.

Association of Common CRP Gene Variants with CRP Levels and Cardiovascular Events

N. Cook, P. Ridker, D. Chasman, 2005, Annals of human genetics.

Is smoking an indirect risk factor for the development of ulcerative colitis? An age‐ and sex‐matched case–control study

R. Lazarus, W. Selby, M. Solomon, 2003, Journal of gastroenterology and hepatology.

Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids.

S. Gabriel, D. Altshuler, E. Lander, 2004, Human molecular genetics.

ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts.

E. Bleecker, A. Litonjua, C. Lange, 2008, American journal of respiratory and critical care medicine.

TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples.

E. Silverman, C. Lange, R. Lazarus, 2004, American journal of respiratory and critical care medicine.

T-bet polymorphisms are associated with asthma and airway hyperresponsiveness.

J. Rioux, E. Silverman, K. Van Steen, 2006, American journal of respiratory and critical care medicine.

Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes.

Mousheng Xu, G. Diette, T. Pastinen, 2010, Human molecular genetics.

GGtools: analysis of genetics of gene expression in bioconductor

Robert Gentleman, Ross Lazarus, Vincent J. Carey, 2007, Bioinform..

Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies.

E. Silverman, L. Palmer, R. Lazarus, 2003, Genomics.

Single-nucleotide polymorphisms in the interleukin-10 gene: differences in frequencies, linkage disequilibrium patterns, and haplotypes in three United States ethnic groups.

E. Silverman, L. Palmer, R. Lazarus, 2002, Genomics.

Chromosome 17: association of a large inversion polymorphism with corticosteroid response in asthma

Ross Lazarus, Scott T Weiss, Barbara Klanderman, 2008, Pharmacogenetics and genomics.

Eotaxin polymorphisms and serum total IgE levels in children with asthma.

E. Silverman, J. Celedón, R. Lazarus, 2006, The Journal of allergy and clinical immunology.

Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes.

T. Hudson, E. Silverman, C. Greenwood, 2002, American journal of respiratory and critical care medicine.

Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease

E. Silverman, L. Palmer, M. Ramoni, 2002, Immunological reviews.

A genome-wide association study of bronchodilator response in asthmatics

J. Celedón, A. Litonjua, W. Qiu, 2013, The Pharmacogenomics Journal.

A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma.

T. Mariani, J. Celedón, D. Warburton, 2010, American journal of respiratory and critical care medicine.

Lack of Association Between Genetic Variation in 9 Innate Immunity Genes and Baseline CRP Levels

N. Cook, P. Ridker, D. Chasman, 2006, Annals of human genetics.

Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma

Ross Lazarus, Scott T Weiss, Stephen Lake, 2005, Respiratory research.

Toll-like receptor 10 ( TLR 10 ) genetic variation is associated with asthma in two independent samples

E. Silverman, C. Lange, R. Lazarus, 2004 .

A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9.

R. Lazarus, G. Genovese, G. Appel, 2010, Kidney international.

Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer.

D. Hunter, P. Kraft, E. Giovannucci, 2005, Cancer research.

strength among older adults: the Rancho Bernardo Study Sex differences in the association of fasting and postchallenge glucose levels with grip

L. Ferrucci, S. Kong, B. Nan, 2015 .

DDH149 1353..1359

S. Gabriel, D. Altshuler, E. Lander, 2004 .

Overview of the pharmacogenetics of asthma treatment

E. Bleecker, A. Litonjua, C. Lange, 2006, The Pharmacogenomics Journal.

IL1B polymorphisms modulate cystic fibrosis lung disease

M. Drumm, J. Celedón, F. Zou, 2009, Pediatric pulmonology.

Polymorphisms in the interleukin 17F gene (IL17F) and asthma

J. Celedón, C. Camargo, R. Lazarus, 2005, Genes and Immunity.

Asthma-susceptibility variants identified using probands in case-control and family-based analyses

E. Silverman, G. O'Connor, J. Celedón, 2010, BMC Medical Genetics.

Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.

Christoph Lange, Edwin K Silverman, Ross Lazarus, 2009, American journal of respiratory and critical care medicine.

Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes.

E. Silverman, A. Randolph, C. Lange, 2005, American journal of respiratory and critical care medicine.

Association of defensin β-1 gene polymorphisms with asthma

E. Silverman, R. Lazarus, D. Kwiatkowski, 2005 .

The IL12B gene is associated with asthma.

E. Silverman, A. Randolph, C. Lange, 2004, American journal of human genetics.

ADAM33 polymorphisms and phenotype associations in childhood asthma.

E. Silverman, C. Lange, R. Lazarus, 2004, The Journal of allergy and clinical immunology.

IL10 gene polymorphisms are associated with asthma phenotypes in children

N. Laird, E. Silverman, A. Randolph, 2004, Genetic epidemiology.

Chromosome 12q harbors multiple genetic loci related to asthma and asthma-related phenotypes.

E. Silverman, C. Lange, R. Lazarus, 2003, Human molecular genetics.

Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis

Weiliang Qiu, Eric E Schadt, Blanca E Himes, 2014, BMC Medical Genomics.

immune response to physiological stress exercise reveals novel signaling mechanisms in the Transcriptome analysis of neutrophils after endurance

A. Bulmer, R. Lazarus, D. Cameron-Smith, 2014 .

Transcriptome analysis of neutrophils after endurance exercise reveals novel signaling mechanisms in the immune response to physiological stress.

A. Bulmer, R. Lazarus, D. Cameron-Smith, 2013, Journal of applied physiology.

Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.

S. Chanock, D. Hunter, P. Kraft, 2009, Human molecular genetics.

Balancing Selection Is the Main Force Shaping the Evolution of Innate Immunity Genes1

T. Marquès-Bonet, J. Bertranpetit, A. Navarro, 2008, The Journal of Immunology.

Minimal haplotype tagging

Paola Sebastiani, Ross Lazarus, Isaac S Kohane, 2003, Proceedings of the National Academy of Sciences of the United States of America.

This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon.

Jaume Bertranpetit, Hafid Laayouni, Ludovica Montanucci, 2011 .

Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.

H. Coon, B. Make, E. Silverman, 2010, American journal of respiratory and critical care medicine.

Quantifying differential gene connectivity between disease states for objective identification of disease-relevant genes

Ross Lazarus, Vincent J. Carey, Jen-hwa Chu, 2011, BMC Systems Biology.

Association between Toll-Like Receptor Gene Cluster (TLR6, TLR1, and TLR10) and Prostate Cancer

D. Hunter, P. Kraft, E. Giovannucci, 2007, Cancer Epidemiology Biomarkers & Prevention.

Platform dependence of inference on gene-wise and gene-set involvement in human lung development

J. Steven Leeder, Scott T. Weiss, Ross Lazarus, 2009, BMC Bioinformatics.

Association of defensin beta-1 gene polymorphisms with asthma.

E. Silverman, R. Lazarus, D. Kwiatkowski, 2005, The Journal of allergy and clinical immunology.

Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma

E. Silverman, L. Palmer, R. Lazarus, 2004, Genes and Immunity.

Genetic determinants of emphysema distribution in the national emphysema treatment trial.

B. Make, E. Silverman, E. Hoffman, 2007, American journal of respiratory and critical care medicine.

Stronger evidence for replication of NPPA using genome-wide genotyping data.

E. Silverman, J. Celedón, C. Lange, 2010, American Journal of Respiratory and Critical Care Medicine.

Genome-wide linkage analysis of pulmonary function in families of children with asthma in Costa Rica

N. Freimer, T. Hudson, E. Silverman, 2006, Thorax.

The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids.

E. Bleecker, R. Lazarus, S. Peters, 2009, The Journal of allergy and clinical immunology.

A new multimarker test for family‐based association studies

Xin Xu, Ross Lazarus, Deborah Blacker, 2007, Genetic epidemiology.

Extracting principal diagnosis, co-morbidity and smoking status for asthma research: evaluation of a natural language processing system

Scott T. Weiss, Qing Zeng-Treitler, Margarita Sordo, 2006, BMC Medical Informatics Decis. Mak..

Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis

T. Beaty, E. Burchard, Bin Zhang, 2014, BMC Medical Genomics.

Polymorphisms in the IL-1 Gene Family and Lung Disease Severity in Patients with Cystic Fibrosis

M. Drumm, J. Celedón, F. Zou, 2012 .

Handgrip strength and insulin levels: cross-sectional and prospective associations in the Normative Aging Study.

R. Lazarus, D. Sparrow, R. Lazarus, 1997, Metabolism: clinical and experimental.

Baseline ventilatory function predicts the development of higher levels of fasting insulin and fasting insulin resistance index: the Normative Aging Study.

S. Weiss, R. Lazarus, D. Sparrow, 1998, The European respiratory journal.

Impaired ventilatory function and elevated insulin levels in nondiabetic males: the Normative Aging Study.

R. Lazarus, D. Sparrow, S. Weiss, 1998, The European respiratory journal.

Alcohol intake and insulin levels. The Normative Aging Study.

R. Lazarus, D. Sparrow, R. Lazarus, 1997, American journal of epidemiology.

Introduction to Integrated Bioinformatic Resources for Cytokine Genetics Research

R. Lazarus, 2006 .

Costa Rica function in families of children with asthma in Genome-wide linkage analysis of pulmonary Freimer

N. Freimer, T. Hudson, E. Silverman, 2007 .

Effects of obesity and fat distribution on ventilatory function: the normative aging study.

R. Lazarus, D. Sparrow, R. Lazarus, 1997, Chest.