C. Mcintosh

发表

H. Mclennan, J. R. Ledsome, C. Mcintosh, 1987, Springer US.

Glucose-dependent Insulinotropic Polypeptide (GIP) Stimulation of Pancreatic β-Cell Survival Is Dependent upon Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (PKB) Signaling, Inactivation of the Forkhead Transcription Factor Foxo1, and Down-regulation of bax Expression*

C. Mcintosh, Su-jin Kim, Kyle Winter, 2005, Journal of Biological Chemistry.

Inhibition of Dipeptidyl Peptidase IV With Sitagliptin (MK0431) Prolongs Islet Graft Survival in Streptozotocin-Induced Diabetic Mice

D. Doudet, C. Mcintosh, Su-jin Kim, 2008, Diabetes.

Dipeptidyl Peptidase IV Inhibitors for Treatment of Diabetes

R. Pederson, C. Mcintosh, Su-jin Kim, 2011 .

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV.

R. Pederson, C. Mcintosh, T. Kieffer, 1995, Endocrinology.

Dipeptidyl peptidase IV inhibition in animal models of diabetes.

R. Pederson, C. Mcintosh, H. Demuth, 2003, Advances in experimental medicine and biology.

Dipeptidyl peptidase IV inhibitor treatment stimulates β-cell survival and islet neogenesis in streptozotocin-induced diabetic rats

R. Pederson, C. Mcintosh, H. Demuth, 2003 .

Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.

R. Pederson, C. Mcintosh, H. Demuth, 2003, Diabetes.

Type 2 diabetes--therapy with dipeptidyl peptidase IV inhibitors.

R. Pederson, C. Mcintosh, H. Demuth, 2005, Biochimica et biophysica acta.

Applications of dipeptidyl peptidase IV inhibitors in diabetes mellitus.

R. Pederson, C. Mcintosh, Su-jin Kim, 2006, The international journal of biochemistry & cell biology.

Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival

S. Gambhir, D. Doudet, C. Mcintosh, 2006, Nature Medicine.

Seeing is believing: in vivo functional real-time imaging of transplanted islets using positron emission tomography (PET)

S. Gambhir, D. Doudet, C. Mcintosh, 2006 .

Glucose-Dependent Insulinotropic Polypeptide-Mediated Up-Regulation of β-Cell Antiapoptotic Bcl-2 Gene Expression Is Coordinated by Cyclic AMP (cAMP) Response Element Binding Protein (CREB) and cAMP-Responsive CREB Coactivator 2

C. Mcintosh, Su-jin Kim, C. Nian, 2007, Molecular and Cellular Biology.

Incretin-stimulated interaction between β-cell Kv1.5 and Kvβ2 channel proteins involves acetylation/deacetylation by CBP/SirT1.

C. Mcintosh, G. Warnock, Su-jin Kim, 2013, The Biochemical journal.

Improved Glucose Tolerance in Zucker Fatty Rats by Oral Administration of the Dipeptidyl Peptidase IV Inhibitor Isoleucine Thiazolidide

R. Pederson, C. Mcintosh, H. Demuth, 1998, Diabetes.

Improved glucose tolerance in rats treated with the dipeptidyl peptidase IV (CD26) inhibitor Ile-thiazolidide.

R. Pederson, C. Mcintosh, H. Demuth, 1999, Metabolism: clinical and experimental.

Rebuttal to Deacon and Holst: "Metformin effects on dipeptidyl peptidase IV degradation of glucagon-like peptide-1" versus "Dipeptidyl peptidase inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective".

R. Pederson, C. Mcintosh, H. Demuth, 2002, Biochemical and biophysical research communications.

On combination therapy of diabetes with metformin and dipeptidyl peptidase IV inhibitors.

R. Pederson, C. Mcintosh, T. Hoffmann, 2002, Diabetes care.

Gastrointestinal somatostatin: distribution, secretion and physiological significance.

C. Mcintosh, 1985, Life sciences.

Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats.

R. Pederson, C. Mcintosh, T. Kieffer, 2001, Diabetes.

A novel pathway for regulation of glucose‐dependent insulinotropic polypeptide receptor expression in β‐cells

R. Pederson, C. Mcintosh, J. Pospisilik, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation

C. Mcintosh, Su-jin Kim, C. Nian, 2011, Journal of Lipid Research.

GIP increases human adipocyte LPL expression through CREB and TORC2-mediated trans-activation of the LPL gene

C. Mcintosh, Su-jin Kim, C. Nian, 2010, Journal of Lipid Research.

Incretin-based Therapies for Type 2 Diabetes.

C. Mcintosh, 2008, Canadian journal of diabetes.

Dipeptidyl peptidase IV inhibitors and diabetes therapy.

C. Mcintosh, 2008, Frontiers in bioscience : a journal and virtual library.

Sitagliptin (MK0431) inhibition of dipeptidyl peptidase IV (DPP-IV) decreases NOD mouse CD4

C. Mcintosh, Su-jin Kim, C. Nian, 2010 .

Inhibition of Dipeptidyl Peptidase IV (DPP-IV) with Sitagliptin (MK0431) Prolongs Islet Graft Survival in Streptozotocin (STZ)-induced Diabetic Mice

D. Doudet, C. Mcintosh, Su-jin Kim, 2008 .

[Ser 2 ]- and [Ser(P) 2 ]Incretin Analogs COMPARISON OF DIPEPTIDYL PEPTIDASE IV RESISTANCE AND BIOLOGICAL ACTIVITIES IN VITRO AND IN VIVO *

R. Pederson, C. Mcintosh, C. Nian, 2004 .

Effect of glucagon-like peptide 1 (7-36 amide) on insulin-mediated glucose uptake in patients with type 1 diabetes.

R. Pederson, C. Mcintosh, J. Egan, 2003, Diabetes care.

Long-term treatment with dipeptidyl peptidase IV inhibitor improves hepatic and peripheral insulin sensitivity in the VDF Zucker rat: a euglycemic-hyperinsulinemic clamp study.

R. Pederson, C. Mcintosh, H. Demuth, 2002, Diabetes.

GIP (Gastric Inhibitory Polypeptide)

R. Pederson, C. Mcintosh, 2004 .

Activation of Lipoprotein Lipase by Glucose-dependent Insulinotropic Polypeptide in Adipocytes

C. Mcintosh, Su-jin Kim, C. Nian, 2007, Journal of Biological Chemistry.

Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and beta-cell glucose responsiveness in VDF (fa/fa) Zucker rats.

R. Pederson, C. Mcintosh, D. Finegood, 2002, Diabetes.

Cysteamine-induced reduction in gastrointestinal somatostatin: evidence for a region-specific loss in immunoreactivity

C. Mcintosh, John C. Brown, Y. Kwok, 1988, Regulatory Peptides.

Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass.

J. Holst, R. Pederson, C. Mcintosh, 2009, American journal of physiology. Endocrinology and metabolism.

Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass.

J. Holst, R. Pederson, C. Mcintosh, 2009, American journal of physiology. Endocrinology and metabolism.

Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties.

J. Brown, R. Pederson, C. Mcintosh, 1995, Endocrinology.

Effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-I-(7-36) on insulin secretion.

J. Brown, R. Pederson, C. Mcintosh, 1995, The American journal of physiology.

Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis.

R. Pederson, C. Mcintosh, Yuichiro Yamada, 2003, American journal of physiology. Endocrinology and metabolism.

Dipeptidyl peptidase IV inhibitors: how do they work as new antidiabetic agents?

R. Pederson, C. Mcintosh, H. Demuth, 2005, Regulatory Peptides.

A New Pathway for Glucose-dependent Insulinotropic Polypeptide (GIP) Receptor Signaling

R. Pederson, C. Mcintosh, J. Ehses, 2001, The Journal of Biological Chemistry.

[Ser2]- and [Ser(P)2]Incretin Analogs

R. Pederson, C. Mcintosh, C. Nian, 2004, Journal of Biological Chemistry.

Dipeptidyl peptidase IV-resistant [D-Ala(2)]glucose-dependent insulinotropic polypeptide (GIP) improves glucose tolerance in normal and obese diabetic rats.

R. Pederson, C. Mcintosh, C. Nian, 2002, Diabetes.

Metabolism of glucagon by dipeptidyl peptidase IV (CD26)

R. Pederson, C. Mcintosh, T. Hoffmann, 2001, Regulatory Peptides.

Effects of dipeptidyl peptidase IV on the satiety actions of peptide YY

C. Mcintosh, S. Unniappan, H. Demuth, 2006, Diabetologia.

Resistin Is a Key Mediator of Glucose-dependent Insulinotropic Polypeptide (GIP) Stimulation of Lipoprotein Lipase (LPL) Activity in Adipocytes*

C. Mcintosh, Su-jin Kim, C. Nian, 2007, Journal of Biological Chemistry.

Localization of the domains involved in ligand binding and activation of the glucose-dependent insulinotropic polypeptide receptor.

R. Pederson, C. Mcintosh, C. Nian, 1997, Endocrinology.

Role of glucose in chronic desensitization of isolated rat islets and mouse insulinoma (betaTC-3) cells to glucose-dependent insulinotropic polypeptide.

R. Pederson, C. Mcintosh, H. Demuth, 2000, The Journal of endocrinology.

GIP-Overexpressing Mice Demonstrate Reduced Diet-Induced Obesity and Steatosis, and Improved Glucose Homeostasis

C. Mcintosh, Su-jin Kim, C. Nian, 2012, PloS one.

Reversal of islet GIP receptor down-regulation and resistance to GIP by reducing hyperglycemia in the Zucker rat.

R. Pederson, C. Mcintosh, Su-jin Kim, 2007, Biochemical and biophysical research communications.

Regulation of GIP and GLP1 Receptor Cell Surface Expression by N-Glycosylation and Receptor Heteromerization

C. Mcintosh, E. Accili, F. Lynn, 2012, PloS one.

Structure-Activity Relationships of Glucose-Dependent Insulinotropic Polypeptide (GIP)

R. Pederson, C. Mcintosh, D. Coy, 2003, Biological chemistry.

Glucagon-like peptide-1 (7-37) augments insulin release in elderly patients with diabetes.

R. Pederson, C. Mcintosh, J. Egan, 2001, Diabetes care.

Altered Glucose Dependence of Glucagon-Like Peptide I(7–36)–Induced Insulin Secretion from the Zucker (fa/fa) Rat Pancreas

R. Pederson, C. Mcintosh, R. Elliott, 1995, Diabetes.

Gastric inhibitory polypeptide and glucagon-like peptide-1(7-36) amide exert similar effects on somatostatin secretion but opposite effects on gastrin secretion from the rat stomach.

J. Brown, R. Pederson, C. Mcintosh, 1994, Canadian journal of physiology and pharmacology.

Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice.

R. Pederson, D. Drucker, C. Mcintosh, 1998, Diabetes.

Somatostatin and insulin release from isolated rat pancreatic islets stimulated by glucose

C. Mcintosh, W. Creutzfeldt, H. Frerichs, 1976, FEBS letters.

Relative contribution of incretins to the glucose lowering effect of DP IV inhibitors in type 2 diabetes mellitus (T2DM).

R. Pederson, C. Mcintosh, S. Hinke, 2006, Advances in experimental medicine and biology.

Gastrointestinal somatostatin: extraction and radioimmunoassay in different species.

C. Mcintosh, W. Creutzfeldt, J. Köbberling, 1978, Gut.

Gastrointestinal somatostatin in man and dog.

C. Mcintosh, W. Creutzfeldt, R. Arnold, 1978, Metabolism: clinical and experimental.

3 – Purification and Chemical Structure of Porcine and Canine Motilins and Evidence for the Existence of Motilin in Other Species

J. Brown, C. Mcintosh, 1990 .

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function.

C. Mcintosh, K. Maedler, J. Kerr-Conte, 2015, Human molecular genetics.

Effect of Fasting on the Release of Insulin and Somatostatin from Perifused Islets of Langerhans

C. Mcintosh, H. Frerichs, P. Schauder, 1979, Diabetes.

Dynamics of somatostatin release from isolated rat pancreatic islets

C. Mcintosh, W. Creutzfeldt, H. Frerichs, 1977, FEBS letters.

Somatostatin and insulin release from isolated rat pancreatic islets in response to D-glucose, l-leucine, alpha-ketoisocaproic acid or D-glyceraldehyde: evidence for a regulatory role of adenosine-3' ,5'-cyclic monophosphate.

C. Mcintosh, W. Creutzfeldt, H. Frerichs, 1977, Biochemical and biophysical research communications.

Control of Gastric Acid Secretion and the Endocrine Pancreas by Gastrointestinal Regulatory Peptides

C. Mcintosh, 1995 .

Dynamics of somatostatin and insulin release from isolated rat pancreatic islets: evidence for intraislet interactions between B cells and D cells.

C. Mcintosh, W. Creutzfeldt, H. Frerichs, 1978, Metabolism: clinical and experimental.

Glucose-Dependent Insulinotropic Polypeptide-Mediated Up-Regulation of (cid:2) -Cell Antiapoptotic Bcl-2 Gene Expression Is Coordinated by Cyclic AMP (cAMP) Response Element Binding Protein (CREB) and cAMP-Responsive CREB Coactivator 2 (cid:1)

C. Mcintosh, Su-jin Kim, C. Nian, 2008 .

An immunocytochemical investigation with monoclonal antibodies to somatostatin

J. Brown, C. Mcintosh, J. Levy, 2004, Histochemistry.

Gastric inhibitory polypeptide stimulated secretion of somatostatinlike immunoreactivity from the stomach: inhibition by acetylcholine or vagal stimulation.

J. Brown, R. Pederson, C. Mcintosh, 1981, Canadian journal of physiology and pharmacology.

Glucose-Dependent Insulinotropic Polypeptide Stimulation of Lipolysis in Differentiated 3T3-L1 Cells: Wortmannin-Sensitive Inhibition by Insulin* * This work was supported by grants from Zymogenetics Inc. (Seattle, WA), the Medical Research Council of Canada (5-90007-RAP/CHSM) and the Canadian Diabe

R. Pederson, C. Mcintosh, G. McKnight, 1999, Endocrinology.

Glucose-dependent insulinotropic polypeptide stimulation of lipolysis in differentiated 3T3-L1 cells: wortmannin-sensitive inhibition by insulin.

R. Pederson, C. Mcintosh, G. McKnight, 1999, Endocrinology.

Effect of a purified somatostatin monoclonal antibody and its Fab fragments on gastrin release.

J. Brown, C. Mcintosh, A. Malcolm, 1991, The American journal of physiology.

Adrenergic control of rat gastric somatostatin and gastrin release.

R. Pederson, C. Mcintosh, W. Creutzfeldt, 1983, Scandinavian journal of gastroenterology.

Increased somatostatin secretion from pancreatic islets of streptozotocin-diabetic rats in response to glucose

C. Mcintosh, W. Creutzfeldt, H. Frerichs, 1980, Molecular and Cellular Endocrinology.

Immuno-Electron Microscopic Study of Differential Localization of Motilin and Serotonin in the Rabbit Duodenal Epithelium

M. Fujimiya, C. Mcintosh, S. St.-Pierre, 1998, Peptides.

Somatostatin immunoreactivity in the cat adrenal medulla

J. Brown, P. Reiner, S. Vincent, 1987, Histochemistry.

Adrenergic modulation of gastric somatostatin release in rats

R. Pederson, C. Mcintosh, W. Creutzfeldt, 1980, FEBS letters.

GIP6–30amide contains the high affinity binding region of GIP and is a potent inhibitor of GIP1–42action in vitro

R. Pederson, C. Mcintosh, M. Wheeler, 1997, Regulatory Peptides.

The insulinotropic region of gastric inhibitory polypeptide; fragment analysis suggests the bioactive site lies between residues 19 and 30.

J. Brown, R. Pederson, C. Mcintosh, 1996, Canadian journal of physiology and pharmacology.

Beta-funaltrexamine blockade of opioid-induced inhibition of somatostatin secretion from rat stomach.

C. Mcintosh, V. Yago, Y. Kwok, 1994, European journal of pharmacology.

Cholinergic stimulation of neuropeptide Y secretion from the isolated perfused rat stomach

C. Mcintosh, Y. Kwok, A. Dadgar, 1992, Regulatory Peptides.

The effects of substance P, histamine and histamine antagonists on somatostatin and gastrin release from the isolated perfused rat stomach

C. Mcintosh, John C. Brown, Y. Kwok, 1987, Regulatory Peptides.

Release of [Leu5]enkephalin immunoreactivity from the isolated perfused rat stomach.

C. Mcintosh, E. Nishimura, 1986, European journal of pharmacology.

Autonomic nervous control of gastric somatostatin secretion from the perfused rat stomach.

R. Pederson, C. Mcintosh, J. Brown, 1981, Life sciences.

Characterization of acetylcholine-induced increases in cytosolic free calcium concentration in individual rat pancreatic beta-cells.

J. Brown, C. Mcintosh, C. Verchere, 1994, Cell adhesion and communication.

Pancreatic β-cell prosurvival effects of the incretin hormones involve post-translational modification of Kv2.1 delayed rectifier channels

C. Mcintosh, G. Warnock, C. Nian, 2011, Cell Death and Differentiation.

Somatostatin and gastrin release from canine stomach.

C. Mcintosh, W. Creutzfeldt, H. Koop, 1980, Scandinavian journal of gastroenterology.

The release of somatostatin-14 from human submucosal ganglia in tissue culture.

C. Mcintosh, E. Accili, A. Buchan, 1993, Canadian journal of physiology and pharmacology.

Identification of a bioactive domain in the amino-terminus of glucose-dependent insulinotropic polypeptide (GIP).

R. Pederson, C. Mcintosh, H. Demuth, 2001, Biochimica et biophysica acta.

A comparison of the inhibitory effects of somatostatin-14, -25, and -28 on motility of the guinea pig ileum.

J. Brown, C. Mcintosh, Y. Kwok, 1986, Canadian journal of physiology and pharmacology.

GIP(6-30amide) contains the high affinity binding region of GIP and is a potent inhibitor of GIP1-42 action in vitro.

R. Pederson, C. Mcintosh, M. Wheeler, 1997, Regulatory peptides.

Glucose-dependent insulinotropic polypeptide (GIP): development of DP IV-resistant analogues with therapeutic potential.

R. Pederson, C. Mcintosh, H. Demuth, 2003, Advances in experimental medicine and biology.

From the Department of Cellular & Physiological Sciences and the Diabetes Research Group, Life Sciences Institute, University

D. Doudet, C. Mcintosh, Su-jin Kim, 2008 .

Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase.

R. Pederson, C. Mcintosh, Kyle Winter, 2003, Endocrinology.

GIP receptors and signal-transduction mechanisms.

J. Brown, R. Pederson, C. Mcintosh, 1996, Acta physiologica Scandinavica.

Resistin Knockout Mice Exhibit Impaired Adipocyte Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR) Expression

C. Mcintosh, Su-jin Kim, C. Nian, 2013, Diabetes.

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function.

C. Mcintosh, K. Maedler, J. Kerr-Conte, 2009, Human molecular genetics.

Autoradiographic Localization of μ- and δ-Type Opioid Receptors in the Gastrointestinal Tract of the Rat and Guinea Pig

C. Mcintosh, E. Nishimura, A. Buchan, 1986 .

Vagal release of IR-VIP and IR-gastrin from the isolated perfused rat stomach

R. Pederson, C. Mcintosh, John Brown, 1981, Molecular and Cellular Endocrinology.

Glucose-dependent insulinotropic polypeptide (Gastric Inhibitory Polypeptide; GIP).

C. Mcintosh, Su-jin Kim, S. Widenmaier, 2009, Vitamins and hormones.

Structure-function analysis of a series of novel GIP analogues containing different helical length linkers.

R. Pederson, C. Mcintosh, H. Demuth, 2003, Biochemistry.

Characterization of the opioid receptor type mediating inhibition of rat gastric somatostatin secretion.

C. Mcintosh, X. Jia, Y. N. Kowk, 1990, The American journal of physiology.

Enkephalinergic control of somatostatin secretion from the perfused rat stomach.

R. Pederson, C. Mcintosh, E. Nishimura, 1983 .

The isolation and characterization of rabbit motilin precursor cDNA.

C. Mcintosh, R. MacGillivray, D. Banfield, 1992 .

Central somatostatin systems revealed with monoclonal antibodies

J. Brown, S. Vincent, C. Mcintosh, 1985, The Journal of comparative neurology.

Comparison of α-ketoisocaproic acid and glucose in rats: Effects on insulin and somatostatin release and on islet camp content

C. Mcintosh, H. Frerichs, U. Panten, 1978, Molecular and Cellular Endocrinology.

Autoradiographic localization of mu- and delta-type opioid receptors in the gastrointestinal tract of the rat and guinea pig.

C. Mcintosh, E. Nishimura, A. Buchan, 1986, Gastroenterology.

Dipeptidyl Peptidase IV Inhibition With MK0431 Improves Islet Graft Survival in Diabetic NOD Mice Partially via T-Cell Modulation

D. Doudet, C. Mcintosh, Su-jin Kim, 2009, Diabetes.

Suppression of p38 MAPK and JNK via Akt-mediated Inhibition of Apoptosis Signal-regulating Kinase 1 Constitutes a Core Component of the β-Cell Pro-survival Effects of Glucose-dependent Insulinotropic Polypeptide*

C. Mcintosh, G. Warnock, Su-jin Kim, 2009, The Journal of Biological Chemistry.

Contractile effects of cysteamine on the guinea‐pig ileum

C. Mcintosh, E. Nishimura, J. Brown, 1984, British journal of pharmacology.

Release of substance P-like immunoreactivity from the vascularly perfused rat stomach.

C. Mcintosh, Y. Kwok, 1990, European journal of pharmacology.

Isolation from porcine intestinal extracts of a cholecystokinin-like peptide and a peptide with homology to cytochrome oxidase polypeptide VII and chymodenin.

N. Spruston, J. Brown, V. Mutt, 1988, Canadian journal of physiology and pharmacology.

The effect of muscarinic and beta-adrenergic blockade on cysteamine-induced gastrin secretion by the isolated perfused rat stomach.

J. Brown, C. Mcintosh, Y. Kwok, 1987, Life sciences.

Effect of substance P on somatostatin release from the isolated perfused rat stomach.

J. Brown, R. Pederson, C. Mcintosh, 1985, Gastroenterology.

Glucose-dependent Insulinotropic Polypeptide Activates the Raf-Mek1/2-ERK1/2 Module via a Cyclic AMP/cAMP-dependent Protein Kinase/Rap1-mediated Pathway*

R. Pederson, C. Mcintosh, S. Pelech, 2002, The Journal of Biological Chemistry.

Expression of recombinant human glucose-dependent insulinotropic polypeptide in Escherichia coli by sequence-specific proteolysis of a protein A fusion protein

R. Pederson, C. Mcintosh, R. MacGillivray, 1990, Peptides.

Amino acid sequence and heterogeneity of gastric inhibitory polypeptide (GIP)

V. Mutt, H. Jörnvall, C. Mcintosh, 1981, FEBS letters.

Glucose‐dependent insulinotropic polypeptide signaling in pancreatic β‐cells and adipocytes

C. Mcintosh, Su-jin Kim, S. Widenmaier, 2012, Journal of diabetes investigation.

A GIP Receptor Agonist Exhibits β-Cell Anti-Apoptotic Actions in Rat Models of Diabetes Resulting in Improved β-Cell Function and Glycemic Control

C. Mcintosh, Su-jin Kim, C. Nian, 2010, PloS one.

Pleiotropic actions of the incretin hormones.

C. Mcintosh, Su-jin Kim, S. Widenmaier, 2010, Vitamins and hormones.

Investigation of Glucose-dependent Insulinotropic Polypeptide(1-42) and Glucagon-like Peptide-1-(7-36) Degradation in Vitro by Dipeptidyl Peptidase IV Using Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry

R. Pederson, C. Mcintosh, M. Wermann, 1996, The Journal of Biological Chemistry.

Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes.

R. Pederson, C. Mcintosh, D. Finegood, 2001, Diabetes care.

Glucagon-like peptide-1 (7-37) augments insulin-mediated glucose uptake in elderly patients with diabetes.

R. Pederson, C. Mcintosh, J. Egan, 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.

Inhibition of bombesin-stimulated gastrin release from isolated canine G cells by bombesin antagonists.

R. Pederson, C. Mcintosh, D. Coy, 1989, Canadian journal of physiology and pharmacology.

Inhibitory actions of tachykinins and neurokinins on release of somatostatin-like immunoreactivity from the isolated perfused rat stomach.

J. Brown, C. Mcintosh, Y. Kwok, 1988, The Journal of pharmacology and experimental therapeutics.

VIP-innervation of rat intestine: A developmental study with monoclonal antibodies

J. Brown, C. Mcintosh, J. Levy, 1984, Peptides.

Effect of carbachol on luminal release of somatostatin from isolated perfused rat duodenum

M. Fujimiya, H. Kimura, C. Mcintosh, 1992, Neuroscience Letters.

Effect of cysteamine on secretion of gastrin and somatostatin from the rat stomach.

J. Brown, R. Pederson, C. Mcintosh, 1984, Gastroenterology.

Gastric inhibitory polypeptide release from a tumor-derived cell line.

J. Brown, R. Pederson, C. Mcintosh, 1995, The American journal of physiology.

Sitagliptin (MK0431) Inhibition of Dipeptidyl Peptidase IV Decreases Nonobese Diabetic Mouse CD4+ T-Cell Migration Through Incretin-Dependent and -Independent Pathways

C. Mcintosh, Su-jin Kim, C. Nian, 2010, Diabetes.

R. Pederson, C. Mcintosh, Kyle Winter, 2003, Endocrinology.

Chronic naltrexone treatment of rats: effects on gastrointestinal opioid peptide content.

C. Mcintosh, V. Bakich, S. Law, 1992, European journal of pharmacology.

Somatostatin and gastrin release into the gastric lumen in rats.

C. Mcintosh, W. Creutzfeldt, H. Koop, 1981, Canadian journal of physiology and pharmacology.

A Novel Mechanism for the Suppression of a Voltage-gated Potassium Channel by Glucose-dependent Insulinotropic Polypeptide

C. Mcintosh, G. Warnock, Su-jin Kim, 2005, Journal of Biological Chemistry.

Decreased TCF 7 L 2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP-and GLP-1 receptors and impaired beta-cell function

C. Mcintosh, K. Maedler, J. Kerr-Conte, 2009 .

Dipeptidyl Peptidase IV (DPIV/CD26) Degradation of Glucagon

R A Pederson, R. Pederson, C. Mcintosh, 2000, The Journal of Biological Chemistry.

Adrenergic and cholinergic interactions in rat gastric somatostatin and gastrin release.

R. Pederson, C. Mcintosh, W. Creutzfeldt, 1982, Digestion.

Discovery of gastric inhibitory polypeptide and its subsequent fate: Personal reflections

R. Pederson, C. Mcintosh, 2016, Journal of diabetes investigation.

Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1.

Hans-Ulrich Demuth, Torsten Hoffmann, R. Pederson, 2002, Biochemical and biophysical research communications.

Gastric Inhibitory Polypeptide (GIP)

R. Pederson, C. Mcintosh, John C. Brown, 1988 .

Glucose-dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 Modulate β-Cell Chromatin Structure*

C. Mcintosh, Su-jin Kim, C. Nian, 2009, Journal of Biological Chemistry.

Autoradiographic localization of binding sites for atrial natriuretic factor.

J. R. Ledsome, C. Mcintosh, H. V. von Schroeder, 1985, Canadian Journal of Physiology and Pharmacology.

Effect of ageing and diabetes on glucose‐dependent insulinotropic polypeptide and dipeptidyl peptidase IV responses to oral glucose

R. Pederson, C. Mcintosh, H. Demuth, 2000, Diabetic medicine : a journal of the British Diabetic Association.

Characterization of the Carboxyl-terminal Domain of the Rat Glucose-dependent Insulinotropic Polypeptide (GIP) Receptor

R. Pederson, C. Mcintosh, M. Wheeler, 1999, The Journal of Biological Chemistry.

Effect of aging and diabetes on the enteroinsular axis.

R. Pederson, C. Mcintosh, J. Egan, 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.

Effect of galanin on endocrine secretions from the isolated perfused rat stomach and pancreas.

J. Brown, C. Mcintosh, C. Verchere, 1988, European journal of pharmacology.

Noncanonical Activation of Akt/Protein Kinase B in β-Cells by the Incretin Hormone Glucose-dependent Insulinotropic Polypeptide*

C. Mcintosh, T. Underhill, S. Widenmaier, 2009, Journal of Biological Chemistry.

The enteroinsular axis in dipeptidyl peptidase IV-negative rats.

R. Pederson, C. Mcintosh, T. Kieffer, 1996, Metabolism: clinical and experimental.

Glucose-dependent insulinotropic polypeptide (Gastric Inhibitory Polypeptide; GIP).

C. Mcintosh, Su-jin Kim, Scott B. Widenmaier, 2009, Vitamins and hormones.