D. Philpott

发表

Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases

J. Hugot, M. Chamaillard, D. Philpott, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia

D. Philpott, S. Girardin, N. Talley, 2022, Brain, Behavior, and Immunity.

The microbial and danger signals that activate Nod-like receptors.

D. Philpott, S. Girardin, S. Benkő, 2008, Cytokine.

Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program.

Andrew Emili, Dajana Vuckovic, A. Emili, 2012, Cell host & microbe.

Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells

B. Wilson, C. Streutker, Alberto Martin, 2014, Cell.

Mitophagy pathways in health and disease

D. Philpott, S. Girardin, Samuel A Killackey, 2020, The Journal of cell biology.

Impaired Resolution of Inflammation in the Endoglin Heterozygous Mouse Model of Chronic Colitis

M. Glogauer, D. Philpott, S. Robertson, 2014, Mediators of inflammation.

The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals.

D. Philpott, C. Werts, Bettina L. Lee, 2008, Immunity.

Nod1 signaling to extracellular mucosal bacteria in epithelial cells

D. Philpott, R. Ferrero, 2005 .

Role for Erbin in Bacterial Activation of Nod2

E. Kremmer, D. Philpott, D. Banks, 2006, Infection and Immunity.

Nod‐like receptors are critical for gut–brain axis signalling in mice

D. Philpott, C. Lebrilla, K. Barrett, 2019, The Journal of physiology.

Nod-like receptors are critical for gut-brain axis signaling

D. Philpott, C. Lebrilla, K. Barrett, 2019, bioRxiv.

Regulation of obesity-related insulin resistance with gut anti-inflammatory agents.

D. Philpott, S. Girardin, E. Engleman, 2015, Cell metabolism.

Regulation of Obesity-Rela ted Insulin Resistance with Gut Anti-inflammatory Agents Graphical

D. Philpott, S. Girardin, E. Engleman, 2022 .

Innate Immune Nod1/RIP2 Signaling Is Essential for Cardiac Hypertrophy but Requires Mitochondrial Antiviral Signaling Protein for Signal Transductions and Energy Balance

D. Philpott, Kyoung-Han Kim, Liyong Zhang, 2020, Circulation.

The innate immune molecule, NOD1, regulates direct killing of Helicobacter pylori by antimicrobial peptides

D. Philpott, I. Boneca, E. Hartland, 2010, Cellular microbiology.

NF-κB Activation during Acute Helicobacter pylori Infection in Mice

D. Philpott, S. Mémet, P. Avé, 2007, Infection and Immunity.

NF-kappaB activation during acute Helicobacter pylori infection in mice.

D. Philpott, S. Mémet, P. Avé, 2008, Infection and immunity.

Recognition of Staphylococcus aureus by the Innate Immune System

D. Philpott, B. Fournier, 2005, Clinical Microbiology Reviews.

NOD1 Activators Link Innate Immunity to Insulin Resistance

D. Philpott, A. Klip, P. Bilan, 2011, Diabetes.

A TNF-α–CCL20–CCR6 Axis Regulates Nod1-Induced B Cell Responses

D. Philpott, J. Gommerman, L. Ward, 2014, The Journal of Immunology.

This information is current as Nod 1-Induced B Cell Responses CCR 6 Axis Regulates − CCL 20 − α A TNF-Gommerman

D. Philpott, Barbara C. Mindt, C. Duerr, 2014 .

The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates

Suneil K. Kalia, D. Philpott, S. Girardin, 2020, The Journal of biological chemistry.

The eIF2α kinase HRI in innate immunity, proteostasis, and mitochondrial stress

D. Philpott, S. Girardin, D. Arnoult, 2020, The FEBS journal.

The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates

Suneil K. Kalia, D. Philpott, S. Girardin, 2020, bioRxiv.

Canonical and noncanonical inflammasomes in intestinal epithelial cells

D. Philpott, S. Girardin, J. Bruce, 2019, Cellular microbiology.

Nod2-Dependent Th2 Polarization of Antigen-Specific Immunity1

D. Philpott, S. Girardin, J. Gommerman, 2008, The Journal of Immunology.

Antigen-Specific Immunity Nod 2-Dependent Th 2 Polarization of and

D. Philpott, S. Girardin, J. Gommerman, 2008 .

The NLR gene family: a standard nomenclature.

Lois J. Maltais, Emad S. Alnemri, Adam Godzik, 2008, Immunity.

Nod2 influences microbial resilience and susceptibility to colitis following antibiotic exposure

C. Streutker, D. Philpott, W. Turpin, 2019, Mucosal Immunology.

Infection of T84 cells with enteropathogenic Escherichia coli alters barrier and transport functions.

D. Philpott, D. McKay, P. Sherman, 1996, The American journal of physiology.

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome.

A. Lau, G. Armstrong, D. Philpott, 2018, Cell reports.

Adenoviral vectors stimulate innate immune responses in macrophages through cross-talk with epithelial cells.

S. Grinstein, D. Philpott, Benjamin H. Lee, 2010, Immunology letters.

Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis.

D. Philpott, S. Girardin, P. Sansonetti, 2013, Cell Host and Microbe.

Mice, Models, Microbiota: How Can We More Accurately Reflect Human Disease?

D. Philpott, Rahman Ladak, 2021, Journal of Undergraduate Life Sciences.

Murine Plasmodium chabaudi Malaria Increases Mucosal Immune Activation and the Expression of Putative HIV Susceptibility Markers in the Gut and Genital Mucosae

R. Kaul, K. Kain, D. Philpott, 2014, Journal of acquired immune deficiency syndromes.

Listeria phospholipases subvert host autophagic defenses by stalling pre‐autophagosomal structures

D. Philpott, S. Girardin, S. Tooze, 2013, The EMBO journal.

Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation

T. Mak, D. Philpott, S. Girardin, 2011, Proceedings of the National Academy of Sciences.

The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling.

J. Bertin, C. Sasakawa, D. Philpott, 2014, Cell host & microbe.

Signal Transduction Pathways Involved in Enterohemorrhagic Escherichia coli-Induced Alterations in T84 Epithelial Permeability

D. Philpott, D. McKay, M. Perdue, 1998, Infection and Immunity.

NLRX1 is a mitochondrial NOD‐like receptor that amplifies NF‐κB and JNK pathways by inducing reactive oxygen species production

D. Philpott, S. Girardin, L. Carneiro, 2008, EMBO reports.

Phosphatidylethanolamine recognition promotes enteropathogenic E. coli and enterohemorrhagic E. coli host cell attachment.

D. Philpott, C. Lingwood, P. Sherman, 1999, Microbial pathogenesis.

Distinct binding properties of eaeA-negative verocytotoxin-producing Escherichia coli of serotype O113:H21

D. Philpott, P. Sherman, J. Brunton, 1994, Infection and immunity.

Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection

J. Hampe, S. Schreiber, P. Rosenstiel, 2006, Cellular microbiology.

Post-transcriptional Inhibition of Luciferase Reporter Assays by the Nod-like Receptor Proteins NLRX1 and NLRC3*

D. Philpott, S. Girardin, L. Carneiro, 2012, The Journal of Biological Chemistry.

Conversion of PtdIns(4,5)P2 into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

M. Sheetz, D. Philpott, P. Sansonetti, 2002, The EMBO journal.

The Impact of the Gut Microbiome on Colorectal Cancer

Alberto Martin, D. Philpott, S. Girardin, 2018 .

Nutrient sensing and metabolic stress pathways in innate immunity

D. Philpott, S. Girardin, Jessica Tsalikis, 2013, Cellular microbiology.

Innate immune responses of epithelial cells following infection with bacterial pathogens.

D. Philpott, S. Girardin, P. Sansonetti, 2001, Current opinion in immunology.

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling

D. Philpott, S. Girardin, L. Carneiro, 2019, Science.

NOD1 mediates non-canonical inflammasome processing of interleukin-18 in epithelial cells to Helicobacter pylori infection

D. Philpott, K. Elgass, S. Masters, 2019, bioRxiv.

Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells

C. Whitchurch, D. Philpott, S. Girardin, 2010, Cellular microbiology.

Isoginkgetin, a Natural Biflavonoid Proteasome Inhibitor, Sensitizes Cancer Cells to Apoptosis via Disruption of Lysosomal Homeostasis and Impaired Protein Clearance

D. Philpott, S. Girardin, Matthew T. Sorbara, 2019, Molecular and Cellular Biology.

Microbial Disruption of Autophagy Alters Expression of the RISC Component AGO2, a Critical Regulator of the miRNA Silencing Pathway

M. Silverberg, D. Philpott, N. Jones, 2015, Inflammatory bowel diseases.

The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner.

D. Philpott, S. Girardin, L. Travassos, 2013, Immunity.

Hypothesis-free analysis of ATG16L1 demonstrates gene-wide extent of association with Crohn's disease susceptibility

M. Silverberg, A. Griffiths, D. Philpott, 2012, Gut.

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

M. Oosting, L. Joosten, M. Netea, 2011, Gut.

'Nodophagy': New crossroads in Crohn disease pathogenesis.

D. Philpott, L. Travassos, Mahendrasingh Ramjeet, 2010, Gut microbes.

Bacterial Invariant NKT Cell Activation during Nod1 and Nod2 Enhance TLR-Mediated

D. Philpott, S. Girardin, T. Mallevaey, 2013 .

Identification of a synthetic muramyl peptide derivative with enhanced Nod2 stimulatory capacity

D. Philpott, S. Girardin, G. Bahr, 2013, Innate immunity.

Nod1 and Nod2 Enhance TLR-Mediated Invariant NKT Cell Activation during Bacterial Infection

D. Philpott, S. Girardin, T. Mallevaey, 2013, The Journal of Immunology.

ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction

J. Rho, D. Philpott, S. Girardin, 2018, The Journal of Biological Chemistry.

Peptidoglycan: a critical activator of the mammalian immune system during infection and homeostasis

D. Philpott, Matthew T. Sorbara, M. Sorbara, 2011, Immunological reviews.

Crohn's disease-associated Nod2 mutants reduce IL10 transcription

D. Philpott, S. Girardin, 2009, Nature Immunology.

Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity

D. Philpott, S. Girardin, A. Klip, 2020, bioRxiv.

Toll‐like receptor 2‐dependent bacterial sensing does not occur via peptidoglycan recognition

D. Philpott, S. Girardin, L. Travassos, 2004, EMBO reports.

The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis

C. Streutker, Alberto Martin, D. Philpott, 2014, The Journal of Biological Chemistry.

Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance.

M. Glogauer, D. Philpott, S. Girardin, 2017, Cell reports.

Male Mice Lacking NLRX1 Are Partially Protected From High-Fat Diet–Induced Hyperglycemia

D. Philpott, S. Girardin, A. Klip, 2018, Journal of the Endocrine Society.

Reduced activation of inflammatory responses in host cells by mouse‐adapted Helicobacter pylori isolates

D. Philpott, A. Labigne, J. Thiberge, 2002, Cellular microbiology.

Gut microbes extend reach to systemic innate immunity

D. Philpott, S. Girardin, 2010, Nature Medicine.

Cyclosporine A Impairs Nucleotide Binding Oligomerization Domain (Nod1)-Mediated Innate Antibacterial Renal Defenses in Mice and Human Transplant Recipients

Christophe Pellefigues, D. Philpott, S. Girardin, 2013, PLoS pathogens.

Nod2 Activates NF-kB in CD4+ T Cells but Its Expression Is Dispensable for T Cell-Induced Colitis

D. Philpott, K. Croitoru, Kaoru Geddes, 2013, PloS one.

Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands

D. Philpott, S. Girardin, S. Rubino, 2011, European journal of immunology.

pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling*

D. Philpott, S. Girardin, S. Vavricka, 2009, The Journal of Biological Chemistry.

NOD2: a potential target for regulating liver injury

J. Hugot, M. Chamaillard, D. Philpott, 2008, Laboratory Investigation.

Nod1 and Nod2 induce CCL5/RANTES through the NF‐κB pathway

D. Philpott, S. Girardin, Xiaojing Ma, 2007 .

Contribution of Phagocytosis and Intracellular Sensing for Cytokine Production by Staphylococcus aureus-Activated Macrophages

D. Philpott, J. Cavaillon, R. Kapetanovic, 2006, Infection and Immunity.

Identification of the Critical Residues Involved in Peptidoglycan Detection by Nod1*

D. Philpott, S. Girardin, P. Sansonetti, 2005, Journal of Biological Chemistry.

Nods and 'intracellular' innate immunity.

D. Philpott, P. Sansonetti, J. Viala, 2004, Comptes rendus biologies.

Invariant natural killer T cells minimally influence gut microbiota composition in mice

D. Philpott, D. Guttman, J. Copeland, 2022, Gut microbes.

Innate Immune Molecule NLRC5 Protects Mice From Helicobacter-induced Formation of Gastric Lymphoid Tissue.

D. Philpott, M. D’Elios, B. Jenkins, 2020, Gastroenterology.

T Cell Intrinsic NOD2 Is Dispensable for CD8 T Cell Immunity

D. Philpott, S. Girardin, T. Watts, 2013, PLoS ONE.

Inositol-Triphosphate 3-Kinase C Mediates Inflammasome Activation and Treatment Response in Kawasaki Disease

B. McCrindle, S. Schurmans, D. Philpott, 2016, The Journal of Immunology.

The NOD-Like Receptors

D. Philpott, M. A. Rahman, J. Zhou, 2016 .

What is new with Nods?

D. Philpott, S. Girardin, Matthew T. Sorbara, 2011, Current opinion in immunology.

Circadian GLP-1 Secretion in Mice Is Dependent on the Intestinal Microbiome for Maintenance of Diurnal Metabolic Homeostasis

Alison S. Waller, B. Cox, D. Philpott, 2020, Diabetes.

Bacterial Infection Invariant NKT Cell Activation during Nod1 and Nod2 Enhance TLR-Mediated

D. Philpott, S. Girardin, T. Mallevaey, 2013 .

Nod‐like receptors in intestinal homeostasis, inflammation, and cancer

D. Philpott, S. Girardin, C. Werts, 2011, Journal of leukocyte biology.

Irreversible splenic atrophy following chronic LCMV infection is associated with compromised immunity in mice

D. Philpott, T. Watts, Kaoru Geddes, 2017, European journal of immunology.

Innate Immune Defense Through RNA Interference

D. Philpott, S. Girardin, J. Fritz, 2006, Science's STKE.

A single cell survey of the microbial impacts on the mouse small intestinal epithelium

J. Wrana, D. Philpott, S. Girardin, 2022, Gut microbes.

Cellular microbiology of STEC infections. An overview.

D. Philpott, F. Ebel, 2003, Methods in molecular medicine.

Disruption of Nod-like receptors alters inflammatory response to infection but does not confer protection in experimental cerebral malaria.

K. Kain, D. Philpott, L. Lebourhis, 2009, The American journal of tropical medicine and hygiene.

Report : Disruption of Nod-like Receptors Alters Inflammatory Response to Infection but Does Not Confer Protection in Experimental Cerebral Malaria

K. Kain, D. Philpott, L. Lebourhis, 2009 .

Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation.

T. Mak, S. Ziegler, D. Philpott, 2011, Immunity.

Nod1 Participates in the Innate Immune Response to Pseudomonas aeruginosa*

J. Bertin, M. Plotkowski, D. Philpott, 2005, Journal of Biological Chemistry.

Innate signals from Nod2 block respiratory tolerance and program T(H)2-driven allergic inflammation.

S. Ziegler, D. Philpott, M. Croft, 2010, The Journal of allergy and clinical immunology.

Role of Nod1 in Mucosal Dendritic Cells during Salmonella Pathogenicity Island 1-Independent Salmonella enterica Serovar Typhimurium Infection

D. Philpott, S. Girardin, K. Tedin, 2009, Infection and Immunity.

Role of Nod1 in Mucosal Dendritic Cells during Salmonella Pathogenicity Island 1-Independent Salmonella enterica Serovar Typhimurium Infection

D. Philpott, S. Girardin, K. Tedin, 2009, Infection and Immunity.

NLRP3 Inflammasome the by Leptospiral Glycolipoprotein Activates Downregulation of the Na/K-ATPase Pump

D. Philpott, S. Girardin, A. Vandewalle, 2017 .

Downregulation of the Na/K-ATPase Pump by Leptospiral Glycolipoprotein Activates the NLRP3 Inflammasome

D. Philpott, S. Girardin, C. Werts, 2012, The Journal of Immunology.

Intracellular bacteriolysis triggers a massive apoptotic cell death in Shigella-infected epithelial cells.

G. Rossi, D. Philpott, S. Girardin, 2008, Microbes and infection.

The pattern‐recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction

E. Kremmer, D. Philpott, P. Sansonetti, 2007, Cellular microbiology.

Muramylpeptide shedding modulates cell sensing of Shigella flexneri

G. Rossi, D. Philpott, M. Bernardini, 2008, Cellular microbiology.

NLRC5 deficiency has a moderate impact on immunodominant CD8+ T‐cell responses during rotavirus infection of adult mice

D. Philpott, S. Girardin, J. Gommerman, 2019, Immunology and cell biology.

Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha.

T. Mak, D. Philpott, S. Girardin, 2011, Microbiology.

Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha

T. Mak, D. Philpott, S. Girardin, 2011 .

Review article: In vitro models in inflammatory bowel disease research—a critical review

D. Philpott, D. McKay, M. Perdue, 1997, Alimentary pharmacology & therapeutics.

Alpha-actinin accumulation in epithelial cells infected with attaching and effacing gastrointestinal pathogens.

D. Philpott, P. Sherman, S. Ratnam, 1995, The Journal of infectious diseases.

Signal transduction responses following adhesion of verocytotoxin-producing Escherichia coli

D. Philpott, P. Sherman, P. Sherman, 1995, Infection and immunity.

Increased adherence of Escherichia coli RDEC-1 to human tissue culture cells results in the activation of host signaling pathways.

D. Philpott, P. Sherman, J. Cantey, 1995, The Journal of infectious diseases.

Invasive Shigella flexneri Activates NF-κB Through a Lipopolysaccharide-Dependent Innate Intracellular Response and Leads to IL-8 Expression in Epithelial Cells1

A. Israël, D. Philpott, P. Sansonetti, 2000, The Journal of Immunology.

The pathogenesis of Shigella flexneri infection: lessons from in vitro and in vivo studies.

D. Philpott, P. Sansonetti, J. Edgeworth, 2000, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Invasive Shigella flexneriActivates NF-kB Through a Lipopolysaccharide-Dependent Innate Intracellular Response and Leads to IL-8 Expression in Epithelial Cells

A. Israël, D. Philpott, S. Yamaoka, 2000 .

Enterohemorrhagic Escherichia coli O157:H7 infection and colitis in children.

D. Philpott, P. Sherman, A. Ismaili, 1997, Journal of pediatric gastroenterology and nutrition.

Correction: Malaria Parasite Infection Compromises Control of Concurrent Systemic Non-typhoidal Salmonella Infection via IL-10-Mediated Alteration of Myeloid Cell Function

D. Philpott, S. Luckhart, Kristen L Lokken, 2014, PLoS Pathogens.

Innate immunity: the connection with inflammation and disease.

D. Philpott, S. Girardin, 2009, Seminars in immunology.

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut

D. Philpott, S. Girardin, S. Hapfelmeier, 2011, Nature.

An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix

D. Philpott, S. Girardin, I. Tattoli, 2009, Journal of Cell Science.

Salmonella enterica serovar Typhimurium ΔmsbB Triggers Exacerbated Inflammation in Nod2 Deficient Mice

P. Rosenstiel, D. Philpott, H. Heine, 2014, PloS one.

A new role for intestinal alkaline phosphatase in gut barrier maintenance.

D. Philpott, Kaoru Geddes, 2008, Gastroenterology.

Evidence for correlation between the intensities of adjuvant effects and NOD2 activation by monomeric, dimeric and lipophylic derivatives of N-acetylglucosaminyl-N-acetylmuramyl peptides.

D. Philpott, E. Meshcheryakova, E. Makarov, 2007, Vaccine.

Invading Bacterial Pathogens Activate Transcription Factor EB in Epithelial Cells through the Amino Acid Starvation Pathway of mTORC1 Inhibition

D. Philpott, S. Girardin, Jessica Tsalikis, 2022, Molecular and cellular biology.

The common mouse protozoa Tritrichomonas muris alters mucosal T cell homeostasis and colitis susceptibility

C. Streutker, D. Philpott, S. Girardin, 2016, The Journal of experimental medicine.

Intestinal Batf3-dependent dendritic cells are required for optimal antiviral T-cell responses in adult and neonatal mice

D. Philpott, J. Gommerman, L. Ward, 2016, Mucosal Immunology.

The Intestinal Microbiota: from health to disease, and back.

D. Philpott, S. Girardin, Nayanan Nathan, 2021, Microbes and infection.

Bacterial c-di-GMP Is an Immunostimulatory Molecule1

J. Schroeder, D. Philpott, E. Muraille, 2007, The Journal of Immunology.

The pathogenesis of Shigella (cid:143) exneri infection: lessons from in vitro and in vivo studies

D. Philpott, P. Sansonetti, J. Edgeworth, 2003 .

NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice

D. Philpott, K. Elgass, S. Masters, 2020, Nature communications.

Aspergillus fumigatus Induces Innate Immune Responses in Alveolar Macrophages through the MAPK Pathway Independently of TLR2 and TLR41

J. Latgé, D. Philpott, M. Chignard, 2006, The Journal of Immunology.

Interaction of Aspergillus fumigatus with the alveolar macrophage.

J. Latgé, D. Philpott, M. Chignard, 2006, Medical mycology.

and the MAPK Pathway Independently of TLR2 Responses in Alveolar Macrophages through Induces Innate Immune Aspergillus fumigatus

J. Latgé, D. Philpott, M. Chignard, 2006 .

Trace levels of peptidoglycan in serum underlie the NOD-dependent cytokine response to endoplasmic reticulum stress

D. Philpott, S. Girardin, R. Flick, 2019, The Journal of Biological Chemistry.

Effect of faecal microbial transplant via colonoscopy in patients with severe obesity and insulin resistance: A randomized double‐blind, placebo‐controlled Phase 2 trial

Hyejung Jung, D. Philpott, E. Comelli, 2022, Diabetes, obesity & metabolism.

A Universal Strategy to Promote Secretion of G+/G- Bacterial Extracellular Vesicles and Its Application in Host Innate Immune Responses.

R. Mahadevan, D. Philpott, Jinjin Chen, 2023, ACS synthetic biology.

Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria.

D. Philpott, S. Girardin, I. Tattoli, 2018, Cell host & microbe.

An epithelial armamentarium to sense the microbiota.

D. Philpott, Jooeun Lee, D. Prescott, 2013, Seminars in immunology.

Examining host-microbial interactions through the lens of NOD: From plants to mammals.

D. Philpott, S. Robertson, S. Rubino, 2012, Seminars in immunology.

Bacterial infection causes stress-induced memory dysfunction in mice

G. MacQueen, D. Philpott, M. Gareau, 2010, Gut.

Innate immunity via Toll-like receptors and Nod proteins.

D. Philpott, R. Athman, 2004, Current opinion in microbiology.

Overview of the Bacterial Pathogens

W. Goebel, D. Philpott, P. Sansonetti, 2002 .

Nod-like proteins in immunity, inflammation and disease

D. Philpott, S. Girardin, J. Fritz, 2006, Nature Immunology.

Modulating immunity as a therapy for bacterial infections

Robert E. W. Hancock, Anastasia Nijnik, R. Hancock, 2012, Nature Reviews Microbiology.

The multifaceted role of the intestinal microbiota in colon cancer.

Alberto Martin, D. Philpott, S. Girardin, 2014, Molecular cell.

Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants

S. Bertholet, D. Philpott, E. De Gregorio, 2014, Proceedings of the National Academy of Sciences.

Nod-like receptors: sentinels at host membranes.

D. Philpott, S. Girardin, Dana J Philpott, 2010, Current opinion in immunology.

TIR, CARD and PYRIN: three domains for an antimicrobial triad

D. Philpott, S. Girardin, C. Werts, 2006, Cell Death and Differentiation.

Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan

J. Bertin, P. Distefano, D. Philpott, 2003, Science.

VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1

D. Philpott, R. Peek, M. Helmrath, 2019, Nature Microbiology.

Intracellular vs extracellular recognition of pathogens--common concepts in mammals and flies.

D. Philpott, S. Girardin, P. Sansonetti, 2002, Trends in microbiology.

NOD proteins: regulators of inflammation in health and disease

D. Philpott, S. Girardin, Matthew T. Sorbara, 2013, Nature Reviews Immunology.

The impact of dextran sodium sulphate and probiotic pre-treatment in a murine model of Parkinson’s disease

D. Philpott, K. Storey, Hongyu Sun, 2021, Journal of Neuroinflammation.

LRRK2 and Nod2 promote lysozyme sorting in Paneth cells

D. Philpott, M. Schlossmacher, J. Rocha, 2015, Nature Immunology.

How autophagy controls the intestinal epithelial barrier

D. Philpott, S. Girardin, Tapas Mukherjee, 2021, Autophagy.

Primed PMNs in healthy mouse and human circulation are first responders during acute inflammation.

J. W. Chadwick, M. Glogauer, D. Philpott, 2019, Blood advances.

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

D. Philpott, S. Girardin, G. Núñez, 2010, Nature Immunology.

Peptidoglycan Molecular Requirements Allowing Detection by Nod1 and Nod2*

D. Philpott, S. Girardin, P. Sansonetti, 2003, Journal of Biological Chemistry.

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

John Bertin, J. Bertin, P. Distefano, 2004, Nature Immunology.

Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection*

M. Chamaillard, D. Philpott, S. Girardin, 2003, The Journal of Biological Chemistry.

CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri

J. Bertin, P. Distefano, G. Stark, 2001 .

Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.

D. Philpott, S. Girardin, H. Fsihi, 2007, Immunity.

Mini‐review: The role of peptidoglycan recognition in innate immunity

D. Philpott, S. Girardin, 2004, European journal of immunology.

Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells.

C. Streutker, Alberto Martin, D. Philpott, 2021, Cell reports.

ATG16L1 protects from IFN-γ-induced cell death in the small intestinal crypt.

C. Streutker, D. Philpott, S. Girardin, 2023, Mucosal immunology.

NOD1 and NOD2 in inflammation, immunity and disease.

D. Philpott, S. Girardin, Tapas Mukherjee, 2019, Archives of biochemistry and biophysics.

The interplay between microbes and the immune response in inflammatory bowel disease

D. Philpott, K. Croitoru, A. Goethel, 2018, The Journal of physiology.

'Nodophagy': New cross-roads in Crohn's disease pathogenesis

D. Philpott, L. Travassos, Mahendrasingh Ramjeet, 2010 .

Resilience of the intestinal microbiota following pathogenic bacterial infection is independent of innate immunity mediated by NOD1 or NOD2.

C. Streutker, D. Philpott, S. Robertson, 2016, Microbes and infection.

Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin

P. Rosenstiel, M. Chamaillard, D. Philpott, 2016, Nature Medicine.

Nod1 and Nod2 Regulation of Inflammation in the Salmonella Colitis Model

C. Streutker, D. Philpott, S. Girardin, 2010, Infection and Immunity.

The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition.

C. Streutker, D. Philpott, S. Girardin, 2017, Cell reports.

The Cytosolic Microbial Receptor Nod2 Regulates Small Intestinal Crypt Damage and Epithelial Regeneration following T Cell–Induced Enteropathy

C. Streutker, D. Philpott, K. Croitoru, 2016, The Journal of Immunology.

Disruption of autophagy by increased 5-HT alters gut microbiota and enhances susceptibility to experimental colitis and Crohn’s disease

Yun Han Kwon, M. Surette, D. Philpott, 2021, Science advances.

Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans.

M. Silverberg, C. Streutker, D. Philpott, 2012, Gastroenterology.

Nod-like receptors in the control of intestinal inflammation.

D. Philpott, S. Girardin, S. Rubino, 2012, Current opinion in immunology.

NOD-like receptors: versatile cytosolic sentinels.

D. Philpott, F. Soares, T. Sun, 2015, Physiological reviews.

Constitutive induction of intestinal Tc17 cells in the absence of hematopoietic cell‐specific MHC class II expression

C. Streutker, D. Philpott, S. Girardin, 2013, European journal of immunology.

NKT Cell–Deficient Mice Harbor an Altered Microbiota That Fuels Intestinal Inflammation during Chemically Induced Colitis

C. Streutker, D. Philpott, D. Guttman, 2016, The Journal of Immunology.

The transcriptional and splicing landscape of intestinal organoids undergoing nutrient starvation or endoplasmic reticulum stress

B. Blencowe, Q. Pan, D. Philpott, 2016, BMC Genomics.

Nods, Nalps and Naip: intracellular regulators of bacterial‐induced inflammation

M. Chamaillard, D. Philpott, S. Girardin, 2003, Cellular microbiology.

Stalling autophagy: a new function for Listeria phospholipases

D. Philpott, S. Girardin, I. Tattoli, 2014, Microbial cell.

Shigella flexneri infection is dependent on villin in the mouse intestine and in primary cultures of intestinal epithelial cells

D. Philpott, P. Sansonetti, P. Gounon, 2005, Cellular microbiology.

IκBε-Deficient Mice: Reduction of One T Cell Precursor Subspecies and Enhanced Ig Isotype Switching and Cytokine Synthesis

A. Israël, D. Philpott, P. Sansonetti, 1999, The Journal of Immunology.

Isotype Switching and Cytokine Synthesis Precursor Subspecies and Enhanced Ig -Deficient Mice: Reduction of One T Cell e B k I

A. Israël, D. Philpott, P. Sansonetti, 1999 .

The dialogue between unconventional T cells and the microbiota

D. Philpott, T. Mallevaey, Meggie Kuypers, 2020, Mucosal Immunology.

INVASIVE BACTERIAL INFECTION INDUCES CELLULAR STRESS THAT ALTERS THE CYTOPLASMIC DYNAMICS OF THE SMN COMPLEX

D. Philpott, A. Ling, Chloe Yang, 2011 .

Gut symbionts dial up RA to prime host defense.

D. Philpott, Jitender Yadav, Nayanan Nathan, 2021, Cell host & microbe.

Comparison of Co-housing and Littermate Methods for Microbiota Standardization in Mouse Models.

D. Philpott, S. Girardin, D. Guttman, 2019, Cell reports.

Innate Immune Influences on the Gut Microbiome: Lessons from Mouse Models.

D. Philpott, S. Girardin, S. Robertson, 2018, Trends in immunology.

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

R. Kaul, C. Streutker, D. Philpott, 2011, Nature Medicine.

Epithelial ion transport and barrier abnormalities evoked by superantigen-activated immune cells are inhibited by interleukin-10 but not interleukin-4.

D. Philpott, P. Yang, J. Lu, 1998, The Journal of pharmacology and experimental therapeutics.

Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

David S. Park, R. Padmore, D. Philpott, 2011, Journal of Neural Transmission.

Innate Immune Sensing of Microbes by Nod Proteins

D. Philpott, D. Banks, T. Kufer, 2006, Annals of the New York Academy of Sciences.

CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.

J. Bertin, P. Distefano, G. Stark, 2001, EMBO reports.

Commensal and Probiotic Bacteria Influence Intestinal Barrier Function and Susceptibility to Colitis in Nod1−/−;Nod2−/− Mice

D. Philpott, K. McCoy, Y. Sanz, 2012, Inflammatory bowel diseases.

Nod proteins link bacterial sensing and autophagy

D. Philpott, S. Girardin, L. Carneiro, 2010, Autophagy.

Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum

K. Kelly, D. Philpott, T. Darville, 2006, Cellular microbiology.

SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling

S. Grinstein, Jane Y. Wu, M. Glogauer, 2020, Nature Communications.

Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development.

M. Surette, Bo Li, Guoji Guo, 2022, Immunity.

Innate immune recognition at the epithelial barrier drives adaptive immunity: APCs take the back seat.

D. Philpott, J. Fritz, Dana J Philpott, 2008, Trends in immunology.

NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation.

C. Streutker, D. Philpott, S. Girardin, 2016, Cell reports.

Lrrk2 alleles modulate inflammation during microbial infection of mice in a sex-dependent manner

David S. Park, J. Rioux, D. Philpott, 2019, Science Translational Medicine.

Inhibition of Helicobacter pylori and Helicobacter mustelae binding to lipid receptors by bovine colostrum.

D. Philpott, H. Karch, C. Lingwood, 1998, The Journal of infectious diseases.

NOD proteins: regulators of inflammation in health and disease

D. Philpott, S. Girardin, Matthew T. Sorbara, 2013, Nature Reviews Immunology.

Towards an understanding of the role of NOD2/CARD15 in the pathogenesis of Crohn's disease.

D. Philpott, J. Viala, 2004, Best practice & research. Clinical gastroenterology.

The Frameshift Mutation in Nod2 Results in Unresponsiveness Not Only to Nod2- but Also Nod1-activating Peptidoglycan Agonists*

M. Netea, D. Philpott, S. Girardin, 2005, Journal of Biological Chemistry.

Synergistic stimulation of human monocytes and dendritic cells by Toll‐like receptor 4 and NOD1‐ and NOD2‐activating agonists

D. Philpott, S. Girardin, J. Cavaillon, 2005, European journal of immunology.

Nod1 and Nod2 signaling does not alter the composition of intestinal bacterial communities at homeostasis

D. Philpott, S. Girardin, S. Robertson, 2013, Gut microbes.

Intracellular Bacterial Pathogens Trigger the Formation of U Small Nuclear RNA Bodies (U Bodies) through Metabolic Stress Induction*

D. Philpott, S. Girardin, I. Tattoli, 2015, The Journal of Biological Chemistry.

The role of Toll-like receptors and Nod proteins in bacterial infection.

D. Philpott, S. Girardin, Dana J Philpott, 2004, Molecular immunology.

NLRC5 Limits the Activation of Inflammatory Pathways

D. Philpott, S. Girardin, S. Benkő, 2010, Journal of Immunology.

Diurnal changes in the murine small intestine are disrupted by obesogenic Western Diet feeding and microbial dysbiosis

D. Philpott, A. Martchenko, P. Brubaker, 2021, Scientific Reports.

Microbial induction of CARD15 expression in intestinal epithelial cells via toll‐like receptor 5 triggers an antibacterial response loop

M. Chamaillard, D. Philpott, O. Goulet, 2006, Journal of cellular physiology.

Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity.

Trevor J Pugh, T. Pugh, A. McGuigan, 2022, Immunity.

Intra- and inter-species interactions drive early phases of invasion in mice gut microbiota

Adrian W. R. Serohijos, D. Philpott, C. Hui, 2022, bioRxiv.

Nod1 and Nod2 and the Immune Response to Bacteria

D. Philpott, M. Kaparakis-Liaskos, 2013 .

Genetic profiling in inflammatory bowel disease: from association to bedside.

A. Griffiths, D. Philpott, J. V. van Limbergen, 2011, Gastroenterology.

NLRs: Nucleotide-Binding Domain and Leucine-Rich-Repeat-Containing Proteins.

D. Philpott, L. Carneiro, L. Travassos, 2009, EcoSal Plus.

A function for AAMP in Nod2-mediated NF-kappaB activation.

D. Philpott, P. Sansonetti, T. Kufer, 2009, Molecular immunology.

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system

M. Prevost, J. Bertin, J. Hugot, 2007, Proceedings of the National Academy of Sciences.

Innate immune recognition of microbes through Nod1 and Nod2: implications for disease.

D. Philpott, L. Carneiro, L. Travassos, 2004, Microbes and infection.

Title Nod 1 and Nod 2 regulation of inflammation in the Salmonella colitis model

C. Streutker, D. Philpott, S. Girardin, 2010 .

Mammalian NLR proteins; discriminating foe from friend

D. Philpott, R. Ferrero, Maria Kaparakis, 2007, Immunology and cell biology.

Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells.

M. Plotkowski, D. Philpott, S. Girardin, 2009, Cell host & microbe.

Neutrophil migration during liver injury is under nucleotide-binding oligomerization domain 1 control.

D. Philpott, S. Girardin, P. Sansonetti, 2010, Gastroenterology.

Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin

J. Bertin, J. Hugot, D. Philpott, 2005, EMBO reports.

NOD-Like Receptors: Guardians of Intestinal Mucosal Barriers.

D. Philpott, A. Claes, J. Zhou, 2015, Physiology.

Defined mouse microbiota: An "evolving" tool.

D. Philpott, G. Bayer, 2021, Cell host & microbe.

NLRX 1 is a mitochondrial NOD-like receptor that amplifies NFk B and JNK pathways by inducing reactive oxygen species production

D. Philpott, S. Girardin, L. Carneiro, 2008 .

NOD2 activation induces muscle cell-autonomous innate immune responses and insulin resistance.

D. Philpott, A. Klip, K. Foley, 2010, Endocrinology.

NOD2 modulates immune tolerance via the GM-CSF–dependent generation of CD103+ dendritic cells

D. Philpott, S. Girardin, S. Rubino, 2020, Proceedings of the National Academy of Sciences.

Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway.

D. Philpott, S. Girardin, Xiaojing Ma, 2007, European journal of immunology.

The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1

D. Philpott, S. Girardin, F. Soares, 2018, Molecular and Cellular Biochemistry.

Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

D. Philpott, S. Girardin, D. Arnoult, 2023, bioRxiv.

NACHT-LRR proteins (NLRs) in bacterial infection and immunity.

D. Philpott, J. Fritz, T. Kufer, 2005, Trends in microbiology.

Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis

L. Joosten, M. Netea, D. Philpott, 2008, Proceedings of the National Academy of Sciences.

Activation of P2X7 Receptor by ATP Plays an Important Role in Regulating Inflammatory Responses during Acute Viral Infection

S. Grinstein, D. Philpott, D. Hwang, 2012, PloS one.

NLRC5 Limits the Activation of Inflammatory Pathways

D. Philpott, S. Girardin, S. Benkő, 2010, The Journal of Immunology.

Are the PE‐PGRS proteins of Mycobacterium tuberculosis variable surface antigens?

Sayera Banu, M. Prevost, S. Cole, 2002, Molecular microbiology.

Defined gut microbial communities: promising tools to understand and combat disease.

D. Philpott, E. Allen-Vercoe, C. Ganobis, 2021, Microbes and infection.

O0105 CROHN???S DISEASE AS AN INNATE IMMUNE DEFECT ???THE CRITICAL ROLE OF CARD15 IN INTESTINAL ANTIBACTERIAL DEFENSE

D. Philpott, M. Giovannini, J. Beaulieu, 2004 .

Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and 'involved' IBD patient intestinal tissues.

A. Griffiths, D. Philpott, T. Walters, 2021, American journal of physiology. Gastrointestinal and liver physiology.

New Role of Nod Proteins in Regulation of Intestinal Goblet Cell Response in the Context of Innate Host Defense in an Enteric Parasite Infection

D. Philpott, W. Khan, R. Grencis, 2015, Infection and Immunity.

Paneth cell marker CD24 in NOD2 knockout organoids and in inflammatory bowel disease (IBD)

H. Drummond, J. Satsangi, A. Griffiths, 2013, Gut.

Anti‐CD40L therapy prevents the formation of precursor lesions to gastric B‐cell MALT lymphoma in a mouse model

C. Ong, D. Philpott, Ping Xu, 2023, The Journal of pathology.

Regulation of intestinal glucose transport.

D. Philpott, J. Meddings, J. Butzner, 1992, Canadian journal of physiology and pharmacology.

A gut bacterial strain rescues stunted growth

D. Philpott, Jitender Yadav, 2023, Science.

NLRX1 does not inhibit MAVS-dependent antiviral signalling

D. Philpott, S. Girardin, I. Tattoli, 2013, Innate immunity.

Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1.

D. Philpott, S. Girardin, A. Abdul-Sater, 2022, Molecular cell.

An optimized procedure for quantitative analysis of mitophagy with the mtKeima system using flow cytometry.

D. Philpott, S. Girardin, Nathaniel J Winsor, 2020, BioTechniques.

Escape of intracellular Shigella from autophagy requires binding to cholesterol through the type III effector, IcsB.

D. Philpott, C. A. Kayath, S. Hussey, 2010, Microbes and infection.

Comparison of Helicobacter mustelae and Helicobacter pylori adhesion to eukaryotic cells in vitro.

D. Philpott, S. Czinn, C. Lingwood, 1995, Gastroenterology.

PTU-092 Crohn's disease associated NOD2 variants show differential activation of NF-κb in response to auto-signalling and muramyl dipeptide

A. Griffiths, D. Philpott, S. Girardin, 2012, Gut.

gp130 blockade to NOD off Crohn's disease.

D. Philpott, Tapas Mukherjee, 2021, Trends in immunology.

The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole

D. Philpott, S. Girardin, I. Tattoli, 2012, Biology Open.

Role of Mouse Peptidoglycan Recognition Protein PGLYRP2 in the Innate Immune Response to Salmonella enterica Serovar Typhimurium Infection In Vivo

C. Streutker, D. Philpott, S. Girardin, 2012, Infection and Immunity.

The role of mouse peptidoglycan recognition protein PGLYRP2 in the innate 1

C. Streutker, D. Philpott, Kaoru Geddes, 2012 .

PGRP-LB minds the fort.

D. Philpott, S. Girardin, 2006, Immunity.

Translocation of verotoxin-1 across T84 monolayers: mechanism of bacterial toxin penetration of epithelium.

C. Ackerley, D. Philpott, P. Sherman, 1997, American journal of physiology. Gastrointestinal and liver physiology.

Translocation of verotoxin-1 across T84 monolayers: mechanism of bacterial toxin penetration of epithelium.

C. Ackerley, D. Philpott, P. Sherman, 1997, The American journal of physiology.

Sensing microbes by diverse hosts

B. Lemaître, D. Philpott, S. Girardin, 2003, EMBO reports.

Gut microbiome modified by bariatric surgery improves insulin sensitivity and correlates with increased brown fat activity and energy expenditure

D. Philpott, D. Winer, S. Poutanen, 2023, Cell reports. Medicine.

A Commensal Helicobacter sp. of the Rodent Intestinal Flora Activates TLR2 and NOD1 Responses in Epithelial Cells

D. Philpott, A. Moran, I. Boneca, 2009, PloS one.

Hematopoietic LTβR deficiency results in skewed T cell cytokine profiles during a mucosal viral infection

D. Philpott, J. Gommerman, Conglei Li, 2016, Journal of leukocyte biology.

NLRs: Nucleotide-Binding Domain and Leucine-Rich-Repeat-Containing Proteins.

D. Philpott, L. Carneiro, L. Travassos, 2009, EcoSal Plus.

Nod2 influences microbial resilience and susceptibility to colitis following antibiotic exposure

C. Streutker, D. Philpott, W. Turpin, 2019, Mucosal Immunology.

The effects of Nod-like receptors on adaptive immune responses.

D. Philpott, A. Luchak, B. Tsankov, 2023, Biomedical journal.

The microbial and danger signals that activate Nod-like receptors.

D. Philpott, S. Girardin, Szilvia Benkő, 2008, Cytokine.

Nod‐like proteins in inflammation and disease

D. Philpott, L. Carneiro, L. Travassos, 2008, The Journal of pathology.

The NLR gene family: a standard nomenclature.

A. Godzik, J. Bertin, E. Alnemri, 2008, Immunity.

Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans.

M. Silverberg, C. Streutker, D. Philpott, 2012, Gastroenterology.

Bacterial autophagy

D. Philpott, S. Girardin, I. Tattoli, 2012, Autophagy.

Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance.

M. Glogauer, D. Philpott, S. Girardin, 2017, Cell reports.

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

R. Kaul, C. Streutker, D. Philpott, 2011, Nature Medicine.

Role of Mouse Peptidoglycan Recognition Protein PGLYRP2 in the Innate Immune Response to Salmonella enterica Serovar Typhimurium Infection In Vivo

C. Streutker, D. Philpott, S. Girardin, 2012, Infection and Immunity.

Regulation of obesity-related insulin resistance with gut anti-inflammatory agents.

D. Philpott, S. Girardin, E. Engleman, 2015, Cell metabolism.

Genetic profiling in inflammatory bowel disease: from association to bedside.

A. Griffiths, D. Philpott, J. V. van Limbergen, 2011, Gastroenterology.

IkappaBepsilon-deficient mice: reduction of one T cell precursor subspecies and enhanced Ig isotype switching and cytokine synthesis.

A. Israël, D. Philpott, P. Sansonetti, 1999, Journal of immunology.

VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1

D. Philpott, M. Helmrath, M. Capurro, 2019, Nature Microbiology.

Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells

B. Wilson, C. Streutker, Alberto Martin, 2014, Cell.

Mitochondria-ER cooperation: NLRX1 detects mitochondrial protein import stress and promotes mitophagy through the ER protein RRBP1

D. Philpott, S. Girardin, D. Arnoult, 2022, Autophagy.

3 Cell Biology: an Overview

D. Philpott, P. Boquet, 2004 .

NLRC5 Limits the Activation of Inflammatory Pathways

D. Philpott, S. Girardin, J. Magalhaes, 2010, The Journal of Immunology.