S. Girardin

发表

Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases

J. Hugot, M. Chamaillard, D. Philpott, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia

D. Philpott, S. Girardin, N. Talley, 2022, Brain, Behavior, and Immunity.

The microbial and danger signals that activate Nod-like receptors.

D. Philpott, S. Girardin, S. Benkő, 2008, Cytokine.

Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program.

Andrew Emili, Dajana Vuckovic, A. Emili, 2012, Cell host & microbe.

Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells

B. Wilson, C. Streutker, Alberto Martin, 2014, Cell.

Chronic inflammation: importance of NOD2 and NALP3 in interleukin‐1β generation

S. Girardin, P. Andersen, O. Nielsen, 2006 .

Mitophagy pathways in health and disease

D. Philpott, S. Girardin, Samuel A Killackey, 2020, The Journal of cell biology.

Translation inhibition and metabolic stress pathways in the host response to bacterial pathogens

B. Lemaître, S. Girardin, 2013, Nature Reviews Microbiology.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Regulation of obesity-related insulin resistance with gut anti-inflammatory agents.

D. Philpott, S. Girardin, E. Engleman, 2015, Cell metabolism.

Regulation of Obesity-Rela ted Insulin Resistance with Gut Anti-inflammatory Agents Graphical

D. Philpott, S. Girardin, E. Engleman, 2022 .

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1

Michael I. Wilson, S. Girardin, S. Tooze, 2014, Molecular cell.

The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates

Suneil K. Kalia, D. Philpott, S. Girardin, 2020, The Journal of biological chemistry.

The eIF2α kinase HRI in innate immunity, proteostasis, and mitochondrial stress

D. Philpott, S. Girardin, D. Arnoult, 2020, The FEBS journal.

The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates

Suneil K. Kalia, D. Philpott, S. Girardin, 2020, bioRxiv.

Canonical and noncanonical inflammasomes in intestinal epithelial cells

D. Philpott, S. Girardin, J. Bruce, 2019, Cellular microbiology.

Nod2-Dependent Th2 Polarization of Antigen-Specific Immunity1

D. Philpott, S. Girardin, J. Gommerman, 2008, The Journal of Immunology.

Antigen-Specific Immunity Nod 2-Dependent Th 2 Polarization of and

D. Philpott, S. Girardin, J. Gommerman, 2008 .

The NLR gene family: a standard nomenclature.

Lois J. Maltais, Emad S. Alnemri, Adam Godzik, 2008, Immunity.

Role of AmiA in the Morphological Transition of Helicobacter pylori and in Immune Escape

S. Guadagnini, M. Prevost, S. Girardin, 2006, PLoS pathogens.

Modeling the Regulatory Mechanisms by Which NLRX1 Modulates Innate Immune Responses to Helicobacter pylori Infection

J. Bassaganya-Riera, R. Hontecillas, S. Hoops, 2015, PloS one.

Interleukin-1 signaling induced by Streptococcus suis serotype 2 is strain-dependent and contributes to bacterial clearance and inflammation during systemic disease in a mouse model of infection

S. Girardin, M. Gottschalk, M. Segura, 2019, Veterinary Research.

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome.

A. Lau, G. Armstrong, D. Philpott, 2018, Cell reports.

Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis.

D. Philpott, S. Girardin, P. Sansonetti, 2013, Cell Host and Microbe.

Listeria phospholipases subvert host autophagic defenses by stalling pre‐autophagosomal structures

D. Philpott, S. Girardin, S. Tooze, 2013, The EMBO journal.

Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation

T. Mak, D. Philpott, S. Girardin, 2011, Proceedings of the National Academy of Sciences.

NLRX1 is a mitochondrial NOD‐like receptor that amplifies NF‐κB and JNK pathways by inducing reactive oxygen species production

D. Philpott, S. Girardin, L. Carneiro, 2008, EMBO reports.

The LIM homeobox protein mLIM3/Lhx3 induces expression of the prolactin gene by a Pit‐1/GHF‐1‐independent pathway in corticotroph AtT20 cells

N. Seidah, S. Girardin, S. Benjannet, 1998, FEBS letters.

Triggering receptor expressed on myeloid cells‐1 (TREM‐1) amplifies the signals induced by the NACHT‐LRR (NLR) pattern recognition receptors

M. Netea, S. Girardin, C. Dinarello, 2006, Journal of leukocyte biology.

Post-transcriptional Inhibition of Luciferase Reporter Assays by the Nod-like Receptor Proteins NLRX1 and NLRC3*

D. Philpott, S. Girardin, L. Carneiro, 2012, The Journal of Biological Chemistry.

Emerging themes in bacterial autophagy.

S. Girardin, Matthew T. Sorbara, 2015, Current opinion in microbiology.

NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin

S. Girardin, S. Florquin, J. Roelofs, 2019, PloS one.

Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease

S. Girardin, S. Rubino, S. Florquin, 2012, Biology Open.

Peptidoglycan-Modifying Enzyme Pgp1 Is Required for Helical Cell Shape and Pathogenicity Traits in Campylobacter jejuni

S. Girardin, V. DiRita, W. Vollmer, 2012, PLoS pathogens.

The Impact of the Gut Microbiome on Colorectal Cancer

Alberto Martin, D. Philpott, S. Girardin, 2018 .

Nutrient sensing and metabolic stress pathways in innate immunity

D. Philpott, S. Girardin, Jessica Tsalikis, 2013, Cellular microbiology.

Engagement of NOD2 has a dual effect on proIL‐1β mRNA transcription and secretion of bioactive IL‐1β

L. Joosten, M. Netea, S. Girardin, 2008, European journal of immunology.

IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.

M. Netea, S. Girardin, E. Abraham, 2005, Proceedings of the National Academy of Sciences of the United States of America.

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling

D. Philpott, S. Girardin, L. Carneiro, 2019, Science.

Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells

C. Whitchurch, D. Philpott, S. Girardin, 2010, Cellular microbiology.

Isoginkgetin, a Natural Biflavonoid Proteasome Inhibitor, Sensitizes Cancer Cells to Apoptosis via Disruption of Lysosomal Homeostasis and Impaired Protein Clearance

D. Philpott, S. Girardin, Matthew T. Sorbara, 2019, Molecular and Cellular Biology.

The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner.

D. Philpott, S. Girardin, L. Travassos, 2013, Immunity.

Hypothesis-free analysis of ATG16L1 demonstrates gene-wide extent of association with Crohn's disease susceptibility

M. Silverberg, A. Griffiths, D. Philpott, 2012, Gut.

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

M. Oosting, L. Joosten, M. Netea, 2011, Gut.

Bacterial Invariant NKT Cell Activation during Nod1 and Nod2 Enhance TLR-Mediated

D. Philpott, S. Girardin, T. Mallevaey, 2013 .

Identification of a synthetic muramyl peptide derivative with enhanced Nod2 stimulatory capacity

D. Philpott, S. Girardin, G. Bahr, 2013, Innate immunity.

Nod1 and Nod2 Enhance TLR-Mediated Invariant NKT Cell Activation during Bacterial Infection

D. Philpott, S. Girardin, T. Mallevaey, 2013, The Journal of Immunology.

ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction

J. Rho, D. Philpott, S. Girardin, 2018, The Journal of Biological Chemistry.

Crohn's disease-associated Nod2 mutants reduce IL10 transcription

D. Philpott, S. Girardin, 2009, Nature Immunology.

Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity

D. Philpott, S. Girardin, A. Klip, 2020, bioRxiv.

Toll‐like receptor 2‐dependent bacterial sensing does not occur via peptidoglycan recognition

D. Philpott, S. Girardin, L. Travassos, 2004, EMBO reports.

The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis

C. Streutker, Alberto Martin, D. Philpott, 2014, The Journal of Biological Chemistry.

Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance.

M. Glogauer, D. Philpott, S. Girardin, 2017, Cell reports.

Male Mice Lacking NLRX1 Are Partially Protected From High-Fat Diet–Induced Hyperglycemia

D. Philpott, S. Girardin, A. Klip, 2018, Journal of the Endocrine Society.

Gut microbes extend reach to systemic innate immunity

D. Philpott, S. Girardin, 2010, Nature Medicine.

Palmitoylation of NOD1 and NOD2 is required for bacterial sensing

N. Warner, S. Girardin, B. Raught, 2019, Science.

Cyclosporine A Impairs Nucleotide Binding Oligomerization Domain (Nod1)-Mediated Innate Antibacterial Renal Defenses in Mice and Human Transplant Recipients

Christophe Pellefigues, D. Philpott, S. Girardin, 2013, PLoS pathogens.

Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands

D. Philpott, S. Girardin, S. Rubino, 2011, European journal of immunology.

pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling*

D. Philpott, S. Girardin, S. Vavricka, 2009, The Journal of Biological Chemistry.

NOD2: a potential target for regulating liver injury

J. Hugot, M. Chamaillard, D. Philpott, 2008, Laboratory Investigation.

Nucleotide Oligomerization Domains 1 and 2: Regulation of Expression and Function in Preadipocytes1

S. Girardin, M. Zeitz, M. Heimesaat, 2008, The Journal of Immunology.

Nod1 and Nod2 induce CCL5/RANTES through the NF‐κB pathway

D. Philpott, S. Girardin, Xiaojing Ma, 2007 .

Nod1 and Nod2 in innate immunity and human inflammatory disorders.

S. Girardin, S. Benkő, L. Le Bourhis, 2007, Biochemical Society transactions.

Nucleotide Oligomerization Domain 2 (Nod2) Is Not Involved in the Pattern Recognition of Candida albicans

B. Franke, M. Netea, S. Girardin, 2006, Clinical and Vaccine Immunology.

hPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides.

S. Girardin, S. Vavricka, M. Fried, 2006, Canadian journal of physiology and pharmacology.

NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype.

M. Netea, S. Girardin, D. D. de Jong, 2005, The Netherlands journal of medicine.

Identification of the Critical Residues Involved in Peptidoglycan Detection by Nod1*

D. Philpott, S. Girardin, P. Sansonetti, 2005, Journal of Biological Chemistry.

for the Induction of Cytokine Release Domain-2 Modulates Specific TLR Pathways Nucleotide-Binding Oligomerization

L. Jacobs, M. Netea, S. Girardin, 2005 .

Nucleotide-Binding Oligomerization Domain-2 Modulates Specific TLR Pathways for the Induction of Cytokine Release 1

L. Jacobs, M. Netea, S. Girardin, 2005, Journal of Immunology.

T Cell Intrinsic NOD2 Is Dispensable for CD8 T Cell Immunity

D. Philpott, S. Girardin, T. Watts, 2013, PLoS ONE.

NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart

S. Girardin, R. Kibbey, S. Houten, 2020, Frontiers in Immunology.

What is new with Nods?

D. Philpott, S. Girardin, Matthew T. Sorbara, 2011, Current opinion in immunology.

Title : Bacterial membrane vesicles deliver peptidoglycan to NOD 1 in epithelial cells

C. Whitchurch, S. Girardin, L. Turnbull, 2014 .

Mitochondrial ROS fuel the inflammasome

S. Girardin, Matthew T. Sorbara, 2011, Cell Research.

T Cell + Independent of Their Role in CD4 T Cell Responses to Virus Infection + CD8Tec Kinases Itk and Rlk Are Required for

S. Girardin, P. Sansonetti, R. Bourdet-Sicard, 2006 .

The emerging role of mTOR signalling in antibacterial immunity

S. Girardin, M. Abdel-Nour, Jessica Tsalikis, 2014, Immunology and cell biology.

Bacterial Infection Invariant NKT Cell Activation during Nod1 and Nod2 Enhance TLR-Mediated

D. Philpott, S. Girardin, T. Mallevaey, 2013 .

Nod‐like receptors in intestinal homeostasis, inflammation, and cancer

D. Philpott, S. Girardin, C. Werts, 2011, Journal of leukocyte biology.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

No difference in renal injury and fibrosis between wild-type and NOD1/NOD2 double knockout mice with chronic kidney disease induced by ureteral obstruction

S. Girardin, M. Dessing, S. Florquin, 2018, BMC Nephrology.

An Endogenous Nanomineral Chaperones Luminal Antigen and Peptidoglycan to Intestinal Immune Cells

P. Midgley, R. Lechler, S. Girardin, 2015, Nature nanotechnology.

Innate Immune Defense Through RNA Interference

D. Philpott, S. Girardin, J. Fritz, 2006, Science's STKE.

A single cell survey of the microbial impacts on the mouse small intestinal epithelium

J. Wrana, D. Philpott, S. Girardin, 2022, Gut microbes.

Nod1 Participates in the Innate Immune Response to Pseudomonas aeruginosa*

J. Bertin, M. Plotkowski, D. Philpott, 2005, Journal of Biological Chemistry.

NLRP1B and NLRP3 Control the Host Response following Colonization with the Commensal Protist Tritrichomonas musculis

C. Streutker, S. Girardin, A. Mortha, 2021, The Journal of Immunology.

Role of Nod1 in Mucosal Dendritic Cells during Salmonella Pathogenicity Island 1-Independent Salmonella enterica Serovar Typhimurium Infection

D. Philpott, S. Girardin, K. Tedin, 2009, Infection and Immunity.

Role of Nod1 in Mucosal Dendritic Cells during Salmonella Pathogenicity Island 1-Independent Salmonella enterica Serovar Typhimurium Infection

D. Philpott, S. Girardin, K. Tedin, 2009, Infection and Immunity.

Nod‐like receptors in innate immunity and inflammatory diseases

S. Girardin, L. Carneiro, L. Travassos, 2007, Annals of medicine.

NLRP3 Inflammasome the by Leptospiral Glycolipoprotein Activates Downregulation of the Na/K-ATPase Pump

D. Philpott, S. Girardin, A. Vandewalle, 2017 .

Downregulation of the Na/K-ATPase Pump by Leptospiral Glycolipoprotein Activates the NLRP3 Inflammasome

D. Philpott, S. Girardin, C. Werts, 2012, The Journal of Immunology.

Intracellular bacteriolysis triggers a massive apoptotic cell death in Shigella-infected epithelial cells.

G. Rossi, D. Philpott, S. Girardin, 2008, Microbes and infection.

NLRC5 deficiency has a moderate impact on immunodominant CD8+ T‐cell responses during rotavirus infection of adult mice

D. Philpott, S. Girardin, J. Gommerman, 2019, Immunology and cell biology.

Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha.

T. Mak, D. Philpott, S. Girardin, 2011, Microbiology.

Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha

T. Mak, D. Philpott, S. Girardin, 2011 .

Cellular Aspects of Shigella Pathogenesis: Focus on the Manipulation of Host Cell Processes

S. Girardin, Matthew T. Sorbara, Samuel A. Killackey, 2016, Front. Cell. Infect. Microbiol..

Innate immunity: the connection with inflammation and disease.

D. Philpott, S. Girardin, 2009, Seminars in immunology.

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut

D. Philpott, S. Girardin, S. Hapfelmeier, 2011, Nature.

NLRX1 is not involved in the host defense against Escherichia coli induced pyelonephritis

S. Girardin, S. Florquin, J. Leemans, 2018, F1000Research.

Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing

S. Girardin, Houhui Song, N. Yuan, 2019, Nature Immunology.

An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix

D. Philpott, S. Girardin, I. Tattoli, 2009, Journal of Cell Science.

Enhancement of Reactive Oxygen Species Production and Chlamydial Infection by the Mitochondrial Nod-like Family Member NLRX1

P. Rosenstiel, S. Girardin, D. Ojcius, 2010, The Journal of Biological Chemistry.

Invading Bacterial Pathogens Activate Transcription Factor EB in Epithelial Cells through the Amino Acid Starvation Pathway of mTORC1 Inhibition

D. Philpott, S. Girardin, Jessica Tsalikis, 2022, Molecular and cellular biology.

To the Editor

M. Netea, S. Girardin, G. Ferwerda, 2006 .

Normal responses to specific NOD1 ligands.

M. Netea, S. Girardin, J. V. D. van der Meer, 2006, European journal of immunology.

The common mouse protozoa Tritrichomonas muris alters mucosal T cell homeostasis and colitis susceptibility

C. Streutker, D. Philpott, S. Girardin, 2016, The Journal of experimental medicine.

The Intestinal Microbiota: from health to disease, and back.

D. Philpott, S. Girardin, Nayanan Nathan, 2021, Microbes and infection.

Mammalian PGRPs also mind the fort.

S. Girardin, S. Rubino, Jooeun Lee, 2010, Cell host & microbe.

Trace levels of peptidoglycan in serum underlie the NOD-dependent cytokine response to endoplasmic reticulum stress

D. Philpott, S. Girardin, R. Flick, 2019, The Journal of Biological Chemistry.

Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria.

D. Philpott, S. Girardin, I. Tattoli, 2018, Cell host & microbe.

Synthesis and Biological Evaluation of Biotinyl Hydrazone Derivatives of Muramyl Peptides

S. Girardin, D. Blanot, Jooeun Lee, 2012, Chemical biology & drug design.

Anti-Inflammatory Effect of Lactobacillus casei on Shigella-Infected Human Intestinal Epithelial Cells1

J. Coppee, S. Girardin, P. Sansonetti, 2006, The Journal of Immunology.

Nod-like receptors in intestinal host defense: controlling pathogens, the microbiota, or both?

S. Girardin, S. Robertson, 2013, Current opinion in gastroenterology.

Nod-like proteins in immunity, inflammation and disease

D. Philpott, S. Girardin, J. Fritz, 2006, Nature Immunology.

The multifaceted role of the intestinal microbiota in colon cancer.

Alberto Martin, D. Philpott, S. Girardin, 2014, Molecular cell.

Sending Signals - The microbiota's contribution to intestinal epithelial homeostasis.

S. Girardin, C. Maisonneuve, S. Goyal, 2020, Microbes and infection.

Nod-like receptors: sentinels at host membranes.

D. Philpott, S. Girardin, Dana J Philpott, 2010, Current opinion in immunology.

TIR, CARD and PYRIN: three domains for an antimicrobial triad

D. Philpott, S. Girardin, C. Werts, 2006, Cell Death and Differentiation.

Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan

J. Bertin, P. Distefano, D. Philpott, 2003, Science.

Intracellular vs extracellular recognition of pathogens--common concepts in mammals and flies.

D. Philpott, S. Girardin, P. Sansonetti, 2002, Trends in microbiology.

Oncolytic targeting of renal cell carcinoma via encephalomyocarditis virus

B. Wilson, S. Girardin, L. Ailles, 2010, EMBO molecular medicine.

NOD proteins: regulators of inflammation in health and disease

D. Philpott, S. Girardin, Matthew T. Sorbara, 2013, Nature Reviews Immunology.

NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity

S. Girardin, M. Dessing, S. Florquin, 2017, The Journal of experimental medicine.

Caspase-1 Activation of Lipid Metabolic Pathways in Response to Bacterial Pore-Forming Toxins Promotes Cell Survival

J. Tschopp, S. Girardin, L. Gurcel, 2006, Cell.

How autophagy controls the intestinal epithelial barrier

D. Philpott, S. Girardin, Tapas Mukherjee, 2021, Autophagy.

Unleashing the therapeutic potential of NOD-like receptors

S. Girardin, Kaoru Geddes, J. Magalhaes, 2009, Nature Reviews Drug Discovery.

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

D. Philpott, S. Girardin, G. Núñez, 2010, Nature Immunology.

Peptidoglycan Molecular Requirements Allowing Detection by Nod1 and Nod2*

D. Philpott, S. Girardin, P. Sansonetti, 2003, Journal of Biological Chemistry.

The intestinal epithelial barrier: how to distinguish between the microbial flora and pathogens.

S. Girardin, I. Tattoli, J. Magalhaes, 2007, Seminars in immunology.

Peptidoglycan ld-Carboxypeptidase Pgp2 Influences Campylobacter jejuni Helical Cell Shape and Pathogenic Properties and Provides the Substrate for the dl-Carboxypeptidase Pgp1*

Michael E. Taveirne, S. Girardin, V. DiRita, 2014, The Journal of Biological Chemistry.

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

John Bertin, J. Bertin, P. Distefano, 2004, Nature Immunology.

Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection*

M. Chamaillard, D. Philpott, S. Girardin, 2003, The Journal of Biological Chemistry.

CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri

J. Bertin, P. Distefano, G. Stark, 2001 .

Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.

D. Philpott, S. Girardin, H. Fsihi, 2007, Immunity.

Mini‐review: The role of peptidoglycan recognition in innate immunity

D. Philpott, S. Girardin, 2004, European journal of immunology.

Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells.

C. Streutker, Alberto Martin, D. Philpott, 2021, Cell reports.

ATG16L1 protects from IFN-γ-induced cell death in the small intestinal crypt.

C. Streutker, D. Philpott, S. Girardin, 2023, Mucosal immunology.

NOD1 and NOD2 in inflammation, immunity and disease.

D. Philpott, S. Girardin, Tapas Mukherjee, 2019, Archives of biochemistry and biophysics.

Nod1 and Nod2 Regulation of Inflammation in the Salmonella Colitis Model

C. Streutker, D. Philpott, S. Girardin, 2010, Infection and Immunity.

The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition.

C. Streutker, D. Philpott, S. Girardin, 2017, Cell reports.

Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans.

M. Silverberg, C. Streutker, D. Philpott, 2012, Gastroenterology.

Nod-like receptors in the control of intestinal inflammation.

D. Philpott, S. Girardin, S. Rubino, 2012, Current opinion in immunology.

Constitutive induction of intestinal Tc17 cells in the absence of hematopoietic cell‐specific MHC class II expression

C. Streutker, D. Philpott, S. Girardin, 2013, European journal of immunology.

The transcriptional and splicing landscape of intestinal organoids undergoing nutrient starvation or endoplasmic reticulum stress

B. Blencowe, Q. Pan, D. Philpott, 2016, BMC Genomics.

Nods, Nalps and Naip: intracellular regulators of bacterial‐induced inflammation

M. Chamaillard, D. Philpott, S. Girardin, 2003, Cellular microbiology.

Listeria monocytogenes and Shigella flexneri Activate the NLRP1B Inflammasome

S. Girardin, J. Mogridge, M. Abdel-Nour, 2017, Infection and Immunity.

Stalling autophagy: a new function for Listeria phospholipases

D. Philpott, S. Girardin, I. Tattoli, 2014, Microbial cell.

Mitochondria in innate immunity

S. Girardin, I. Tattoli, F. Soares, 2011, EMBO reports.

Comparison of Co-housing and Littermate Methods for Microbiota Standardization in Mouse Models.

D. Philpott, S. Girardin, D. Guttman, 2019, Cell reports.

Innate Immune Influences on the Gut Microbiome: Lessons from Mouse Models.

D. Philpott, S. Girardin, S. Robertson, 2018, Trends in immunology.

Innate IL-17 and IL-22 responses to enteric bacterial pathogens.

S. Girardin, S. Rubino, Kaoru Geddes, 2012, Trends in immunology.

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

R. Kaul, C. Streutker, D. Philpott, 2011, Nature Medicine.

Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

David S. Park, R. Padmore, D. Philpott, 2011, Journal of Neural Transmission.

THE ROLE OF RELA ( p 65 ) IN REGULATION OF NF-κB HOMEOSTASIS : IMPLICATIONS FOR ATHEROSCLEROSIS

M. Cybulsky, S. Girardin, M. Letarte, 2011 .

Nod proteins link bacterial sensing and autophagy

D. Philpott, S. Girardin, L. Carneiro, 2010, Autophagy.

NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation.

C. Streutker, D. Philpott, S. Girardin, 2016, Cell reports.

Modeling-Enabled Characterization of Novel NLRX1 Ligands

Raquel Hontecillas, Josep Bassaganya-Riera, Vida Abedi, 2015, PloS one.

NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein

S. Girardin, J. McCullers, F. Tzelepis, 2014, Proceedings of the National Academy of Sciences.

NOD proteins: regulators of inflammation in health and disease

D. Philpott, S. Girardin, Matthew T. Sorbara, 2013, Nature Reviews Immunology.

The Frameshift Mutation in Nod2 Results in Unresponsiveness Not Only to Nod2- but Also Nod1-activating Peptidoglycan Agonists*

M. Netea, D. Philpott, S. Girardin, 2005, Journal of Biological Chemistry.

Synergistic stimulation of human monocytes and dendritic cells by Toll‐like receptor 4 and NOD1‐ and NOD2‐activating agonists

D. Philpott, S. Girardin, J. Cavaillon, 2005, European journal of immunology.

Knocking in the NLRP3 inflammasome.

S. Girardin, 2009, Immunity.

A direct interaction between JNK1 and CrkII is critical for Rac1‐induced JNK activation

S. Girardin, M. Yaniv, Moshe Yaniv, 2001, The EMBO journal.

Tissue-selective alternate promoters guide NLRP6 expression

Paul M. K. Gordon, A. Lau, S. Girardin, 2020, Life Science Alliance.

Nod1 and Nod2 signaling does not alter the composition of intestinal bacterial communities at homeostasis

D. Philpott, S. Girardin, S. Robertson, 2013, Gut microbes.

Intracellular Bacterial Pathogens Trigger the Formation of U Small Nuclear RNA Bodies (U Bodies) through Metabolic Stress Induction*

D. Philpott, S. Girardin, I. Tattoli, 2015, The Journal of Biological Chemistry.

Epithelial Cells -Infected Human Intestinal Shigella on casei Lactobacillus Anti-Inflammatory Effect of

J. Coppee, S. Girardin, P. Sansonetti, 2005 .

The role of Toll-like receptors and Nod proteins in bacterial infection.

D. Philpott, S. Girardin, Dana J Philpott, 2004, Molecular immunology.

The role of mitochondria in cellular defense against microbial infection.

S. Girardin, L. Carneiro, I. Tattoli, 2009, Seminars in immunology.

NLRC5 Limits the Activation of Inflammatory Pathways

D. Philpott, S. Girardin, S. Benkő, 2010, Journal of Immunology.

Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway.

C. Arrieumerlou, S. Girardin, S. Gray-Owen, 2017, Cell reports.

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system

M. Prevost, J. Bertin, J. Hugot, 2007, Proceedings of the National Academy of Sciences.

NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis

M. Netea, S. Girardin, D. D. de Jong, 2005, PLoS pathogens.

Title Nod 1 and Nod 2 regulation of inflammation in the Salmonella colitis model

C. Streutker, D. Philpott, S. Girardin, 2010 .

Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells.

M. Plotkowski, D. Philpott, S. Girardin, 2009, Cell host & microbe.

Neutrophil migration during liver injury is under nucleotide-binding oligomerization domain 1 control.

D. Philpott, S. Girardin, P. Sansonetti, 2010, Gastroenterology.

Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin

J. Bertin, J. Hugot, D. Philpott, 2005, EMBO reports.

NLRX 1 is a mitochondrial NOD-like receptor that amplifies NFk B and JNK pathways by inducing reactive oxygen species production

D. Philpott, S. Girardin, L. Carneiro, 2008 .

Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome.

S. Girardin, G. Schmitz, R. Houtkooper, 2018, Biochimica et biophysica acta. Molecular basis of disease.

NOD2 modulates immune tolerance via the GM-CSF–dependent generation of CD103+ dendritic cells

D. Philpott, S. Girardin, S. Rubino, 2020, Proceedings of the National Academy of Sciences.

Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway.

D. Philpott, S. Girardin, Xiaojing Ma, 2007, European journal of immunology.

Cyclic‐di‐GMP and cyclic‐di‐AMP activate the NLRP3 inflammasome

S. Girardin, Lei Jin, C. Schindler, 2013, EMBO reports.

The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1

D. Philpott, S. Girardin, F. Soares, 2018, Molecular and Cellular Biochemistry.

Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

D. Philpott, S. Girardin, D. Arnoult, 2023, bioRxiv.

Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis

L. Joosten, M. Netea, D. Philpott, 2008, Proceedings of the National Academy of Sciences.

Mycobacterium paratuberculosis is recognized by Toll‐like receptors and NOD2

M. Netea, S. Girardin, T. Ottenhoff, 2007, Journal of leukocyte biology.

NLRC5 Limits the Activation of Inflammatory Pathways

D. Philpott, S. Girardin, S. Benkő, 2010, The Journal of Immunology.

Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing.

J. Hugot, S. Girardin, P. Sansonetti, 2003, Trends in immunology.

How Toll-like receptors and Nod-like receptors contribute to innate immunity in mammals

S. Girardin, J. Fritz, Jörg H. Fritz, 2005, Journal of endotoxin research.

The Campylobacter jejuni helical to coccoid transition involves changes to peptidoglycan and the ability to elicit an immune response

S. Girardin, W. Vollmer, S. Huynh, 2019, Molecular microbiology.

Correction: Peptidoglycan-Modifying Enzyme Pgp1 Is Required for Helical Cell Shape and Pathogenicity Traits in Campylobacter jejuni

S. Girardin, V. DiRita, W. Vollmer, 2012, PLoS Pathogens.

The Nodosome: Nod1 and Nod2 control bacterial infections and inflammation

S. Girardin, L. Carneiro, L. Travassos, 2007, Seminars in Immunopathology.

NLRX1 does not inhibit MAVS-dependent antiviral signalling

D. Philpott, S. Girardin, I. Tattoli, 2013, Innate immunity.

Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1.

D. Philpott, S. Girardin, A. Abdul-Sater, 2022, Molecular cell.

An optimized procedure for quantitative analysis of mitophagy with the mtKeima system using flow cytometry.

D. Philpott, S. Girardin, Nathaniel J Winsor, 2020, BioTechniques.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

PTU-092 Crohn's disease associated NOD2 variants show differential activation of NF-κb in response to auto-signalling and muramyl dipeptide

A. Griffiths, D. Philpott, S. Girardin, 2012, Gut.

The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole

D. Philpott, S. Girardin, I. Tattoli, 2012, Biology Open.

Role of Mouse Peptidoglycan Recognition Protein PGLYRP2 in the Innate Immune Response to Salmonella enterica Serovar Typhimurium Infection In Vivo

C. Streutker, D. Philpott, S. Girardin, 2012, Infection and Immunity.

Depletion of microbiota protects the kidney against ischemia/reperfusion injury by reducing granulocyte influx

S. Girardin, S. Rubino, S. Florquin, 2011 .

PGRP-LB minds the fort.

D. Philpott, S. Girardin, 2006, Immunity.

Sensing microbes by diverse hosts

B. Lemaître, D. Philpott, S. Girardin, 2003, EMBO reports.

Cyclic-diGMP and cyclic-diAMP activate the NLRP 3 Inflammasome

S. Girardin, Lei Jin, C. Schindler, 2013 .

The role of mitochondria in cellular defense against microbial infection.

S. Girardin, L. Carneiro, I. Tattoli, 2009, Seminars in immunology.

The microbial and danger signals that activate Nod-like receptors.

D. Philpott, S. Girardin, Szilvia Benkő, 2008, Cytokine.

The NLR gene family: a standard nomenclature.

A. Godzik, J. Bertin, E. Alnemri, 2008, Immunity.

Mitochondria in innate immunity

S. Girardin, I. Tattoli, F. Soares, 2011, EMBO reports.

Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans.

M. Silverberg, C. Streutker, D. Philpott, 2012, Gastroenterology.

Bacterial autophagy

D. Philpott, S. Girardin, I. Tattoli, 2012, Autophagy.

Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing

S. Girardin, Houhui Song, N. Yuan, 2019, Nature Immunology.

Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance.

M. Glogauer, D. Philpott, S. Girardin, 2017, Cell reports.

Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells.

J. Coppee, S. Girardin, P. Sansonetti, 2006, The Journal of Immunology.

IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.

M. Netea, S. Girardin, E. Abraham, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

R. Kaul, C. Streutker, D. Philpott, 2011, Nature Medicine.

Innate immune responses of epithelial cells following infection with bacterial pathogens.

D. Philpott, S. Girardin, P. Sansonetti, 2001, Current opinion in immunology.

Role of Mouse Peptidoglycan Recognition Protein PGLYRP2 in the Innate Immune Response to Salmonella enterica Serovar Typhimurium Infection In Vivo

C. Streutker, D. Philpott, S. Girardin, 2012, Infection and Immunity.

Regulation of obesity-related insulin resistance with gut anti-inflammatory agents.

D. Philpott, S. Girardin, E. Engleman, 2015, Cell metabolism.

Emerging themes in bacterial autophagy.

S. Girardin, Matthew T. Sorbara, 2015, Current opinion in microbiology.

Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells

B. Wilson, C. Streutker, Alberto Martin, 2014, Cell.

NLRX1: Versatile functions of a mitochondrial NLR protein that controls mitophagy

S. Girardin, Samuel A. Killackey, Linus Schweizer, 2023, Biomedical journal.

Mitochondria-ER cooperation: NLRX1 detects mitochondrial protein import stress and promotes mitophagy through the ER protein RRBP1

D. Philpott, S. Girardin, D. Arnoult, 2022, Autophagy.

NLRC5 Limits the Activation of Inflammatory Pathways

D. Philpott, S. Girardin, J. Magalhaes, 2010, The Journal of Immunology.