J. K. Oeser

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Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels

P. Elliott, M. Jarvelin, C. Dina, 2010, Diabetes.

Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult Mouse Islets In Vivo

B. P. Flemming, J. K. Oeser, R. O’Brien, 2008, Diabetes.

Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion.

Richard K P Benninger, David W Piston, David R Powell, 2009, The Biochemical journal.

The Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 is a Pseudogene in Guinea Pigs Potentially Contributing to Low Guinea Pig Islet Zinc Content

J. K. Oeser, R. O’Brien, M. Shiota, 2018, Journal of Molecular Evolution.

Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion.

J. K. Oeser, R. O’Brien, A. Ustione, 2016, Endocrinology.

Accessory Elements, Flanking DNA Sequence, and Promoter Context Play Key Roles in Determining the Efficacy of Insulin and Phorbol Ester Signaling through the Malic Enzyme and Collagenase-1 AP-1 Motifs*

J. K. Oeser, R. O’Brien, J. Ayala, 2002, The Journal of Biological Chemistry.

Selective stimulation of G-6-Pase catalytic subunit but not G-6-P transporter gene expression by glucagon in vivo and cAMP in situ.

J. K. Oeser, R. O’Brien, C. Svitek, 2004, American journal of physiology. Endocrinology and metabolism.

Deletion of the G6pc2 Gene Encoding the Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Does Not Affect the Progression or Incidence of Type 1 Diabetes in NOD/ShiLtJ Mice

J. K. Oeser, R. O’Brien, J. Hutton, 2011, Diabetes.

Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6-P transporter, gene expression by insulin in vivo.

J. K. Oeser, R. O’Brien, J. Ayala, 2001, American journal of physiology. Endocrinology and metabolism.

Hepatocyte nuclear factor-4 a mediates the stimulatory effect of peroxisome proliferator-activated receptor c co-activator-1 a (PGC-1 a ) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells

J. K. Oeser, R. O’Brien, C. Svitek, 2022 .

Protein Kinase A Phosphorylates Hepatocyte Nuclear Factor-6 and Stimulates Glucose-6-phosphatase Catalytic Subunit Gene Transcription*

J. K. Oeser, R. O’Brien, R. Streeper, 2001, The Journal of Biological Chemistry.

Deletion of the Gene Encoding the Ubiquitously Expressed Glucose-6-phosphatase Catalytic Subunit-related Protein (UGRP)/Glucose-6-phosphatase Catalytic Subunit-β Results in Lowered Plasma Cholesterol and Elevated Glucagon*

J. K. Oeser, R. O’Brien, O. McGuinness, 2006, Journal of Biological Chemistry.

Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels

B. Balkau, P. Froguel, N. Bouatia-Naji, 2013, Diabetologia.

Insulin-mediated activation of activator protein-1 through the mitogen-activated protein kinase pathway stimulates collagenase-1 gene transcription in the MES 13 mesangial cell line.

J. K. Oeser, R. O’Brien, J. Ayala, 2004, Journal of molecular endocrinology.

Insulin and epidermal growth factor suppress basal glucose-6-phosphatase catalytic subunit gene transcription through overlapping but distinct mechanisms.

B. P. Flemming, J. K. Oeser, R. O’Brien, 2009, The Biochemical journal.

Effects of G6pc2 deletion on body weight and cholesterol in mice.

J. Denny, J. K. Oeser, R. O’Brien, 2017, Journal of molecular endocrinology.

Upstream stimulatory factor (USF) and neurogenic differentiation/beta-cell E box transactivator 2 (NeuroD/BETA2) contribute to islet-specific glucose-6-phosphatase catalytic-subunit-related protein (IGRP) gene expression.

R. Stein, J. K. Oeser, R. O’Brien, 2003, The Biochemical journal.

Cloning and Characterization of the Human and Rat Islet-specific Glucose-6-phosphatase Catalytic Subunit-related Protein (IGRP) Genes*

P. Froguel, J. K. Oeser, R. O’Brien, 2001, The Journal of Biological Chemistry.

Differential Regulation of Islet-specific Glucose-6-phosphatase Catalytic Subunit-related Protein Gene Transcription by Pax-6 and Pdx-1*

J. K. Oeser, R. O’Brien, Cyrus C. Martin, 2004, Journal of Biological Chemistry.

Sequence variation between the mouse and human glucose-6-phosphatase catalytic subunit gene promoters results in differential activation by peroxisome proliferator activated receptor gamma coactivator-1α

B. P. Flemming, J. K. Oeser, R. O’Brien, 2008, Diabetologia.

Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells

Jamey D. Young, Deveena R. Banerjee, J. K. Oeser, 2022, The Journal of biological chemistry.

The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer.

R. Stein, R. Printz, J. K. Oeser, 2011, The Biochemical journal.

Identification and characterization of a human cDNA and gene encoding a ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein.

J. K. Oeser, R. O’Brien, C. Svitek, 2002, Journal of molecular endocrinology.

The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements.

J. K. Oeser, R. O’Brien, W. Chazin, 2005, Molecular endocrinology.

Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose

L. Davis, J. K. Oeser, R. O’Brien, 2021, The Journal of biological chemistry.

The proximal islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen promoter is sufficient to initiate but not maintain transgene expression in mouse islets in vivo.

J. K. Oeser, R. O’Brien, M. Gannon, 2004, Diabetes.

Characterization of the mouse islet-specific glucose-6-phosphatase catalytic subunit-related protein gene promoter by in situ footprinting: correlation with fusion gene expression in the islet-derived betaTC-3 and hamster insulinoma tumor cell lines.

J. K. Oeser, R. O’Brien, C. Svitek, 2001, Diabetes.

Identification and characterization of a cDNA and the gene encoding the mouse ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein.

J. K. Oeser, R. O’Brien, C. Svitek, 2004, Journal of molecular endocrinology.

Potential positive and negative consequences of ZnT8 inhibition.

Eric P. Skaar, L. Davis, J. K. Oeser, 2020, The Journal of endocrinology.

Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1

J. K. Oeser, R. O’Brien, H. Mchaourab, 2021, The Journal of biological chemistry.

Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype

J. K. Oeser, R. O’Brien, O. McGuinness, 2007, Diabetologia.

Correlation between FOXO1a (FKHR) and FOXO3a (FKHRL1) binding and the inhibition of basal glucose-6-phosphatase catalytic subunit gene transcription by insulin.

J. K. Oeser, R. O’Brien, H. Onuma, 2006, Molecular endocrinology.

The Three Insulin Response Sequences in the Glucose-6-phosphatase Catalytic Subunit Gene Promoter Are Functionally Distinct*

J. K. Oeser, R. O’Brien, D. Powell, 2003, The Journal of Biological Chemistry.

G6PC2 confers protection against hypoglycemia upon ketogenic diet feeding and prolonged fasting

Jamey D. Young, J. K. Oeser, R. O’Brien, 2020, Molecular metabolism.

Pancreatic Islet Beta Cell-Specific Deletion of G6pc2 Reduces Fasting Blood Glucose.

Jamey D. Young, A. Means, L. Davis, 2020, Journal of molecular endocrinology.

Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression

J. K. Oeser, R. O’Brien, Yingda Wang, 2016, PloS one.

G6PC2: A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion

Chandler J. Faulman, J. K. Oeser, R. O’Brien, 2013, Diabetes.

G 6 PC 2 A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion

Brien, Chandler J. Faulman, J. K. Oeser, 2012 .

Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells.

J. K. Oeser, R. O’Brien, C. Svitek, 2003, The Biochemical journal.

Gluconeogenesis: Re-evaluating the FOXO1–PGC-1α connection

B. P. Flemming, J. K. Oeser, R. O’Brien, 2006, Nature.

Characterization of the human SLC30A8 promoter and intronic enhancer.

P. Froguel, J. K. Oeser, R. O’Brien, 2011, Journal of molecular endocrinology.

Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression.

B. P. Flemming, J. K. Oeser, R. O’Brien, 2008, Journal of molecular endocrinology.

Foxa 2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression

B. P. Flemming, J. K. Oeser, R. O’Brien, 2008 .

J. K. Oeser, R. O’Brien, Yingda Wang, 2016, PloS one.

G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance.

J. K. Oeser, R. O’Brien, O. McGuinness, 2016, Endocrinology.

G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.

J. K. Oeser, R. O’Brien, O. McGuinness, 2016, Endocrinology.

G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.

J. K. Oeser, R. O’Brien, O. McGuinness, 2016, Endocrinology.

Evidence that Evolution of the Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 Drives Variations in Pancreatic Islet Zinc Content in Multiple Species

J. Lee, J. K. Oeser, R. O’Brien, 2019, Journal of Molecular Evolution.

Identification of structural motifs critical for human G6PC2 function informed by sequence analysis and an AlphaFold2-predicted model

J. K. Oeser, Emily M Hawes, D. P. Claxton, 2023, Bioscience reports.

Biochemical and metabolic characterization of a G6PC2 inhibitor.

J. K. Oeser, Mohsin Rahim, Zeinab Haratipour, 2024, Biochimie.

Identiﬁcation and characterization of a human cDNA and gene encoding a ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein

J. K. Oeser, C. C. Martin, S. Hunter, 2022 .