Shaoman Yin

发表

On-column purification and refolding of recombinant bovine prion protein: using its octarepeat sequences as a natural affinity tag.

Shaoman Yin, Yi Zheng, P. Tien, 2003, Protein expression and purification.

Identification of a Novel Small Molecule HIF-1α Translation Inhibitor

Erwin G. Van Meir, C. Moreno, Shaoman Yin, 2009, Clinical Cancer Research.

Design and in vitro activities of N -alkyl- N -[(8- R -2,2-dimethyl- 2H -chromen-6-yl)methyl]heteroarylsulfonamides, novel small molecule Hypoxia Inducible Factor-1 (HIF-1) pathway inhibitors and anti-cancer agents

J. Snyder, Erwin G. Van Meir, Shaoman Yin, 2013 .

Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents.

J. Snyder, Erwin G. Van Meir, Shaoman Yin, 2012, Journal of medicinal chemistry.

Cancer Therapy : Preclinical Arylsulfonamide KCN 1 Inhibits In Vivo Glioma Growth and Interfereswith HIF Signaling byDisrupting HIF-1 a Interaction with Cofactors p 300 / CBP

Erwin G. Van Meir, J. Olson, Shaoman Yin, 2012 .

Arylsulfonamide KCN1 Inhibits In Vivo Glioma Growth and Interferes with HIF Signaling by Disrupting HIF-1α Interaction with Cofactors p300/CBP

Erwin G. Van Meir, J. Olson, Shaoman Yin, 2012, Clinical Cancer Research.

Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor.

J. Snyder, Erwin G. Van Meir, Shaoman Yin, 2012, ACS medicinal chemistry letters.

Normal cellular prion protein is a ligand of selectins: binding requires Le(X) but is inhibited by sLe(X).

Shaoman Yin, M. Sy, Binggong Chang, 2007, The Biochemical journal.

Interaction of Doppel with the full-length laminin receptor precursor protein.

Shaoman Yin, P. Tien, M. Sy, 2004, Archives of biochemistry and biophysics.

p53 Pathway Alterations in Brain Tumors

Erwin G. Van Meir, Shaoman Yin, 2009 .

Binding of pro-prion to filamin A disrupts cytoskeleton and correlates with poor prognosis in pancreatic cancer.

Shaoman Yin, F. Nakamura, Derek W. Abbott, 2009, The Journal of clinical investigation.

Pro-prion Binds Filamin A, Facilitating Its Interaction with Integrin β1, and Contributes to Melanomagenesis*

Shaoman Yin, F. Nakamura, W. Xin, 2010, The Journal of Biological Chemistry.

An Aggregation-Specific Enzyme-Linked Immunosorbent Assay: Detection of Conformational Differences between Recombinant PrP Protein Dimers and PrPSc Aggregates

T. Wisniewski, Shaoman Yin, David R. Brown, 2005, Journal of Virology.

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans

Shaoman Yin, P. Tien, D. Harris, 2007, Proceedings of the National Academy of Sciences.

Normal cellular prion protein with a methionine at position 129 has a more exposed helix 1 and is more prone to aggregate.

Shaoman Yin, M. Sy, P. Wong, 2008, Biochemical and biophysical research communications.

Prion Proteins with Insertion Mutations Have Altered N-terminal Conformation and Increased Ligand Binding Activity and Are More Susceptible to Oxidative Attack*

Shaoman Yin, P. Tien, Gengfu Xiao, 2006, Journal of Biological Chemistry.

Ligand binding promotes prion protein aggregation – role of the octapeptide repeats

Shaoman Yin, M. Sy, R. Petersen, 2008, The FEBS journal.

Aggregation of prion protein with insertion mutations is proportional to the number of inserts.

Shaoman Yin, P. Tien, Gengfu Xiao, 2007, The Biochemical journal.

Binding of Recombinant but Not Endogenous Prion Protein to DNA Causes DNA Internalization and Expression in Mammalian Cells*

Shaoman Yin, M. Sy, Chaoyang Li, 2008, Journal of Biological Chemistry.

Test for Detection of Disease-Associated Prion Aggregate in the Blood of Infected but Asymptomatic Animals

T. Wisniewski, Shaoman Yin, Hongtao Zhang, 2006, Clinical and Vaccine Immunology.

Role of the highly conserved middle region of prion protein (PrP) in PrP-lipid interaction.

Fei Wang, Shaoman Yin, M. Sy, 2010, Biochemistry.

Ligand binding promotes prion protein aggregation – role of the octapeptide repeats

Shaoman Yin, M. Sy, R. Petersen, 2008, The FEBS journal.

Identification of a Novel Small Molecule HIF-1α Translation Inhibitor

Erwin G. Van Meir, C. Moreno, Shaoman Yin, 2009, Clinical Cancer Research.

A multistage pathway for human prion protein aggregation in vitro: from multimeric seeds to β-oligomers and nonfibrillar structures.

Yu Huang, Shaoman Yin, M. Plomp, 2011, Journal of the American Chemical Society.