C. Carman

发表

Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion

C. Jun, M. Shimaoka, C. Carman, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Ultrastructure and Function of Dimeric, Soluble Intercellular Adhesion Molecule-1 (ICAM-1)*

C. Jun, M. Shimaoka, C. Carman, 2001, The Journal of Biological Chemistry.

Intravital Imaging of Mesenchymal Stem Cell Trafficking and Association With Platelets and Neutrophils

Charles P. Lin, J. Karp, C. Carman, 2015, Stem cells.

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

Etienne Gagnon, Charles D. Schwieters, Christopher V. Carman, 2008, Cell.

Structural basis of integrin regulation and signaling.

C. Carman, T. Springer, B. Luo, 2007, Annual review of immunology.

Binding and Phosphorylation of Tubulin by G Protein-coupled Receptor Kinases*

C. Carman, J. Benovic, T. Som, 1998, The Journal of Biological Chemistry.

Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates alpha(4) integrins.

D. Peer, M. Shimaoka, C. Carman, 2008, Blood.

Requirement of α and β subunit transmembrane helix separation for integrin outside-in signaling

M. Shimaoka, C. Carman, T. Springer, 2007 .

Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling.

M. Shimaoka, C. Carman, T. Springer, 2007, Blood.

Unexpected enhancement of FVIII immunogenicity by endothelial expression in lentivirus-transduced and transgenic mice.

C. Carman, Yingyu Chen, P. Sage, 2020, Blood advances.

Memory/Effector T Cells Invadosome-like Protrusions Formed by Antigen Recognition Is Facilitated by

C. Carman, T. Springer, A. Sharpe, 2012 .

An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics.

C. Carman, R. Martinelli, 2015, Journal of visualized experiments : JoVE.

Edible Mushrooms Reduce Atherosclerosis in Ldlr-/- Mice Fed a High-Fat Diet.

C. Carman, Dayong Wu, M. Meydani, 2019, The Journal of nutrition.

Regulation of G Protein-coupled Receptor Kinases by Caveolin*

C. Carman, M. Lisanti, J. Benovic, 1999, The Journal of Biological Chemistry.

Differential interaction of GRK2 with members of the Gαqfamily

C. Carman, J. Benovic, P. Wedegaertner, 2003 .

Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2.

M. Caron, C. Carman, J. Benovic, 2000, The Journal of biological chemistry.

Tumor-Derived Extracellular Vesicles Breach the Intact Blood Brain Barrier via Transcytosis.

L. Zon, D. Ingber, Elliott J. Hagedorn, 2019, ACS nano.

Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking

F. Luscinskas, R. Geha, M. Massaad, 2010, Proceedings of the National Academy of Sciences.

Novel Role of CD47 in Rat Microvascular EndotheliumSignificance

G. Newton, F. Luscinskas, C. Carman, 2013 .

Novel Role of CD47 in Rat Microvascular Endothelium: Signaling and Regulation of T-Cell Transendothelial Migration

G. Newton, F. Luscinskas, C. Carman, 2013, Arteriosclerosis, thrombosis, and vascular biology.

T Lymphocyte–Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific Immunity

C. Carman, R. Martinelli, 2015, Front. Immunol..

Lei Yuan, P. Oettgen, W. Aird, 2012, The Journal of Biological Chemistry.

Activation-induced Conformational Changes in the I Domain Region of Lymphocyte Function-associated Antigen 1*

M. Shimaoka, C. Carman, T. Springer, 2002, The Journal of Biological Chemistry.

Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium

C. Carman, T. Michel, M. Tao, 2014, Proceedings of the National Academy of Sciences.

Antiinflammatory Effects of the ETS Factor ERG in Endothelial Cells Are Mediated Through Transcriptional Repression of the Interleukin-8 Gene

M. Bhasin, Lei Yuan, P. Oettgen, 2009, Circulation research.

Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target

D. Peer, M. Shimaoka, C. Carman, 2008, Science.

Immunobiology: Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates α4 integrins

C. Carman, A. Peixoto, U. V. Andrian, 2012 .

A small molecule agonist of an integrin, alphaLbeta2.

M. Shimaoka, C. Carman, T. Springer, 2006, Journal of Biological Chemistry.

Teasing out monocyte trafficking mechanisms.

C. Carman, 2008, Blood.

Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut.

M. Shimaoka, C. Carman, J. Mora, 2007, The Journal of clinical investigation.

Integrin avidity regulation: are changes in affinity and conformation underemphasized?

C. Carman, T. Springer, Timothy A Springer, 2003, Current opinion in cell biology.

Soluble adhesion molecules as markers for sepsis and the potential pathophysiological discrepancy in neonates, children and adults

N. Shapiro, C. Carman, T. Kuijpers, 2014, Critical Care.

Selective Regulation of Gαq/11 by an RGS Domain in the G Protein-coupled Receptor Kinase, GRK2*

C. Carman, A. Gilman, J. Benovic, 1999, The Journal of Biological Chemistry.

Bidirectional Transmembrane Signaling by Cytoplasmic Domain Separation in Integrins

Minsoo Kim, Timothy A. Springer, Christopher V. Carman, 2003, Science.

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway

D. Irvine, Sudha Kumari, Michael Loran Dustin, 2015, eLife.

Transcellular diapedesis is initiated by invasive podosomes.

R. Geha, H. Ochs, H. Dvorak, 2007, Immunity.

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

S. Orkin, R. Bronson, C. Carman, 2003, Nature.

Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology

D. Ingber, J. Scannell, C. Carman, 2022, Communications Medicine.

Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications

D. Ingber, J. Scannell, C. Carman, 2021, bioRxiv.

Aberrant activation of integrin α4β7 suppresses lymphocyte migration to the gut

M. Shimaoka, C. Carman, J. Mora, 2007 .

The primacy of affinity over clustering in regulation of adhesiveness of the integrin αLβ2

Wei Yang, Minsoo Kim, Timothy A. Springer, 2004, The Journal of cell biology.

Transition From Rolling to Firm Adhesion Is Regulated by the Conformation of the I Domain of the Integrin Lymphocyte Function-associated Antigen-1*

M. Shimaoka, C. Carman, T. Springer, 2002, The Journal of Biological Chemistry.

Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin αxβ2

Timothy A. Springer, Motomu Shimaoka, Christopher V. Carman, 2005 .

Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment.

J. Clohessy, P. Pandolfi, E. Palescandolo, 2014, Journal of the National Cancer Institute.

RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion.

G. Freeman, C. Carman, T. Springer, 2004, Developmental cell.

Mechanisms for transcellular diapedesis: probing and pathfinding by `invadosome-like protrusions'

C. Carman, 2009, Journal of Cell Science.

Settings and mechanisms for trans-cellular diapedesis.

C. Carman, P. Sage, 2009, Frontiers in bioscience.

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

Junichi Takagi, C. Carman, J. Takagi, 2005, Proceedings of the National Academy of Sciences of the United States of America.

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood

Loise M. Francisco, C. Carman, A. Sharpe, 2012, Nature Immunology.

Endothelial Cells Proactively Form Microvilli-Like Membrane Projections upon Intercellular Adhesion Molecule 1 Engagement of Leukocyte LFA-1 1

C. Jun, C. Carman, T. Springer, 2003, The Journal of Immunology.

Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds

T. Kirchhausen, C. Carman, T. Springer, 2013, The Journal of cell biology.

Trans-cellular migration: cell-cell contacts get intimate.

C. Carman, T. Springer, 2008, Current opinion in cell biology.

A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them

C. Carman, T. Springer, 2004, The Journal of cell biology.

Regulation of outside-in signaling and affinity by the β2 I domain of integrin αLβ2

C. Carman, T. Springer, Wei Yang, 2006, Proceedings of the National Academy of Sciences.

Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2.

C. Carman, T. Springer, Wei Yang, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Glassy dynamics, cell mechanics, and endothelial permeability.

J. Fredberg, J. Butler, C. Carman, 2013, The journal of physical chemistry. B.

Distinct roles for LFA-1 affinity regulation during T-cell adhesion, diapedesis, and interstitial migration in lymph nodes.

M. Shimaoka, C. Carman, U. V. von Andrian, 2010, Blood.

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces.

J. Fredberg, J. Butler, C. Carman, 2011, American Journal of Physiology - Cell Physiology.

Lymphocyte–Endothelial Interactions

C. Carman, R. Martinelli, 2016 .

G-protein-coupled receptors: turn-ons and turn-offs

C. Carman, J. Benovic, 1998, Current Opinion in Neurobiology.

Active Rap1, a small GTPase that induces malignant transformation of hematopoietic progenitors, localizes in the nucleus and regulates protein expression

Y. Iwamoto, C. Carman, V. Boussiotis, 2007, Leukemia & lymphoma.

Mutational Analysis of Gβγ and Phospholipid Interaction with G Protein-coupled Receptor Kinase 2*

M. Caron, C. Carman, J. Benovic, 2000, The Journal of Biological Chemistry.

Antigen Recognition Is Facilitated by Invadosome-like Protrusions Formed by Memory/Effector T Cells

C. Carman, T. Springer, A. Sharpe, 2012, The Journal of Immunology.

A Small Molecule Agonist of an Integrin, αLβ2*

M. Shimaoka, C. Carman, T. Springer, 2006, Journal of Biological Chemistry.

Cellular and extracellular programming of cell fate through engineered intracrine-, paracrine-, and endocrine-like mechanisms.

J. Karp, C. Carman, J. Ankrum, 2011, Biomaterials.

Mesenchymal Stem Cells Transmigrate Between and Directly Through Tumor Necrosis Factor‐α‐Activated Endothelial Cells Via Both Leukocyte‐Like and Novel Mechanisms

Jeffrey M Karp, James A Ankrum, J. Karp, 2012, Stem cells.

New observations on the trafficking and diapedesis of monocytes

C. Carman, M. Kamei, 2010, Current opinion in hematology.

Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance

Adam S. Zeiger, Matt J. Whitfield, K. V. Van Vliet, 2014, Journal of Cell Science.

Specific and covalent labeling of a membrane protein with organic fluorochromes and quantum dots

Enoch Kim, C. Carman, T. Springer, 2007, Proceedings of the National Academy of Sciences.

High-resolution fluorescence microscopy to study transendothelial migration.

C. Carman, 2012, Methods in molecular biology.

Chapter 10 Transmigratory Cups and Invadosome-Like Protrusions: New Aspects of Diapedesis

C. Carman, 2009 .

Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization

Timothy A. Springer, Christopher V. Carman, Gang Song, 2007, Proceedings of the National Academy of Sciences.

Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.

Motomu Shimaoka, Gang Song, Yong-Sung Kim, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1

J. Lieberman, Pengcheng Zhu, D. Peer, 2007, Proceedings of the National Academy of Sciences.

Overview: imaging in the study of integrins.

C. Carman, 2012, Methods in molecular biology.

The tumor suppressor p53 can promote collective cellular migration

J. Fredberg, J. Butler, C. Carman, 2019, PloS one.

The tumor suppressor p53 promotes carcinoma invasion and collective cellular migration

J. Fredberg, J. Butler, Sam W. Lee, 2018, bioRxiv.

Structure-Function Analysis of G Protein-coupled Receptor Kinase-5

C. Carman, J. Benovic, A. Pronin, 1998, The Journal of Biological Chemistry.

ERG is required for the differentiation of embryonic stem cells along the endothelial lineage

M. Bhasin, Lei Yuan, P. Oettgen, 2009, BMC Developmental Biology.

Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin alphaXbeta2.

M. Shimaoka, C. Carman, T. Springer, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Differential interaction of GRK2 with members of the G alpha q family.

C. Carman, J. Benovic, P. Wedegaertner, 2003, Biochemistry.

Membrane curvature and PS localize coagulation proteins to filopodia and retraction fibers of endothelial cells

W. Lam, C. Carman, V. Novakovic, 2022, Blood advances.

T Lymphocyte–Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific Immunity

C. Carman, R. Martinelli, 2015, Front. Immunol..

Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance

Adam S. Zeiger, Matt J. Whitfield, K. V. Van Vliet, 2014, Journal of Cell Science.

Antiinflammatory Effects of the ETS Factor ERG in Endothelial Cells Are Mediated Through Transcriptional Repression of the Interleukin-8 Gene

M. Bhasin, Lei Yuan, P. Oettgen, 2009, Circulation research.

Cellular and extracellular programming of cell fate through engineered intracrine-, paracrine-, and endocrine-like mechanisms.

J. Karp, C. Carman, J. Ankrum, 2011, Biomaterials.

Antigen Recognition Is Facilitated by Invadosome-like Protrusions Formed by Memory/Effector T Cells

C. Carman, T. Springer, A. Sharpe, 2012, The Journal of Immunology.

Overview: imaging in the study of integrins.

C. Carman, 2012, Methods in molecular biology.

Engagement of Leukocyte LFA-1 Intercellular Adhesion Molecule 1 Microvilli-Like Membrane Projections upon Endothelial Cells Proactively Form

C. Jun, C. Carman, T. Springer, 2003 .

Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology

D. Ingber, J. Scannell, C. Carman, 2023, Communications Medicine.